Search Results
Results 251 - 300 of 947
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Lundh Andreas - - 2009
BACKGROUND: To ensure evidence-based decision making in pediatric oncology systematic reviews are necessary. The objective of our study was to evaluate the methodological quality of all currently existing systematic reviews in pediatric oncology. METHODS: We identified eligible systematic reviews through a systematic search of the literature. Data on clinical and ...
Zaina F - - 2009
AIM: Since 2007 we have been focusing our attention to EJPRM as the best available clinical evidence as offered by the Cochrane Collaboration. Due to the absence of a specific Rehabilitation Group (only a Field does exist), some reviews in the field of PRM are not easy to find. Consequently, ...
Neely J Gail - - 2010
A systematic review is a transparent and unbiased review of available information. The published systematic review must report the details of the conduct of the review as one might report the details of a primary research project. A meta-analysis is a powerful and rigorous statistical approach to synthesize data from ...
Roffey Darren M - - 2010
Low back pain (LBP) is a prevalent and costly musculoskeletal disorder that often occurs in the working-age population. Although numerous physical activities have been implicated in its complex etiology, determining causation remains challenging and requires a methodologically rigorous approach. To conduct a systematic review of the scientific literature focused on ...
Lu Zhengwu - - 2010
To identify key challenges and propose technical considerations in designing electronic case report form (eCRF) for post-marketing studies, the author undertakes a comprehensive literature review of peer reviewed and grey literature to assess the key aspects, processes, standards, recommendations, and best practices in designing eCRFs based on industry experience in ...
Bell Margaret C - - 2009
Even though adverse event (AE) collection and official accounting are mandatory for clinical trials, there are limited detailed guidelines specifying how to summarize the event for reporting in a timely and expeditious manner. This article details the AE and serious adverse event (SAE) reporting summary developed for a large multi-center ...
Visser K - - 2009
OBJECTIVES: To systematically review the literature on liver toxicity in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients treated with methotrexate (MTX), as an evidence base for generating clinical practice recommendations for the management of MTX and the indication for a liver biopsy (LB) in case of elevated liver enzymes ...
Cleary Michelle - - 2009
Access to the most relevant articles with recent evidence is essential for writing peer-reviewed articles and informing clinical decision making. A clear method is needed to undertake a mental health literature review to ensure the topic is covered adequately. Choosing the right key words and search strategies and using appropriate ...
Fleischhacker W Wolfgang - - 2009
BACKGROUND: Second-generation antipsychotics (SGAs) represent an advance in the long-term management of schizophrenia. AIMS: To review the available evidence concerning SGA long-acting injections (LAIs). METHOD: A systematic review of the literature was conducted using PubMed. RESULTS: Risperidone long-acting injection was the first licensed SGA-LAI compound and is effective in the ...
Macedo Cristiane Rufino - - 2009
CONTEXT AND OBJECTIVE: Guidelines are suggestions for clinical practice based on the best available scientific evidence. Nevertheless, in drafting such guidelines, existing systematic reviews are often ignored and are replaced by general consensuses. This ends up compromising the quality of the instructions through bias. Our objective was to investigate whether ...
Patelarou Evridiki - - 2009
We aimed to provide a summary of the existing published knowledge on the association between adverse birth outcomes and the development of wheezing during the first two years of life. We carried out a systematic review of epidemiological studies within the MEDLINE database. Epidemiological studies on human subjects, published in ...
Pitrou Isabelle - - 2009
BACKGROUND: Reports of clinical trials usually emphasize efficacy results, especially when results are statistically significant. Poor safety reporting can lead to misinterpretation and inadequate conclusions about the interventions assessed. Our aim was to describe the reporting of harm-related results from randomized controlled trials (RCTs). METHODS: We searched the MEDLINE database ...
Morin James G - - 2011
The luciferin of the ostracod Vargula hilgendorfii (formerly Cypridina hilgendorfii) is often termed Cypridina luciferin in the scientific literature, but, to avoid ambiguity and based on a review of the literature, is best referred to by the more inclusive term cypridinid luciferin. This situation exemplifies how new knowledge in systematics ...
Williams H C - - 2010
This review summarizes clinically important findings from systematic reviews indexed in bibliographical databases between August 2007 and August 2008 that dealt with disease prevention (six reviews) and treatment of atopic eczema (seven reviews). Regarding disease prevention, two independent systematic reviews found some clinical trial evidence that ingestion of probiotics by ...
Peters Alana - - 2010
This systematic review critically evaluates the quantification of soft tissue artifact (STA) in lower limb human motion analysis. It has a specific focus on assessing the quality of previous studies and comparing quantitative results. A specific search strategy identified 20 published articles or abstracts that fulfilled the selection criteria. The ...
Williams H C - - 2010
This review summarizes clinically important findings from nine systematic reviews indexed in bibliographical databases between August 2007 and August 2008, dealing with the definitions, causes and consequences of atopic eczema (AE). One review of diagnostic criteria found that out of 10 sets of criteria, only the UK refinement of the ...
Givens Carrie B - - 2009
OBJECTIVE: To review the literature regarding the potential interaction between tamoxifen and warfarin. DATA SOURCES: A search of MEDLINE from 1948 to August 20, 2009, was performed using the search terms tamoxifen, warfarin, drug interactions, and cytochrome P450 2C9. EMBASE was searched (1980-week 33, 2009), using the search terms tamoxifen ...
Pearson Mark - - 2010
AIM: To critically evaluate the methods utilized in the conduct of a systematic review in the field of substance misuse. DESIGN: Participant-observation in the review process, semi-structured interviews with review team members and management and structured observation of the process of guidance development. SETTING: An 'arm's-length' government body. PARTICIPANTS: Review ...
Clerici Carlo Alfredo - - 2009
Shocking news of robberies committed using hypnosis on bank cashiers, salespeople, or passers-by has sporadically been reported by the media in countries around the world. The first reported episode in Italy dates to the 1950s. Although the phenomenon has been reported in the papers more frequently in recent years, no ...
Baker W L - - 2009
BACKGROUND: Meta-regression has grown in popularity in recent years, paralleling the increasing numbers of systematic reviews and meta-analysis published in the biomedical literature. However, many clinicians and decision-makers may be unfamiliar with the underlying principles and assumptions made within meta-regression leading to incorrect interpretation of their results. AIMS: This paper ...
Callcut Rachael A - - 2009
Review papers commonly summarize the current knowledge on a selected topic. These types of papers are considered narrative reviews. Narrative reviews rarely detail the methods used to select the literature included, nor do the authors typically report the purpose of the review. Narrative reviews may be biased due to inadequate ...
Eduardo Nigro C C Department of Otolaryngology, Sao Paulo University, Taubaté, Sao Paulo, Brazil. - - 2009
The graph obtained by Acoustic Rhinometry in most studies of normal adult Caucasian individuals clearly shows two notches at the beginning of the rhinogram. However, we found different opinions in the literature regarding the anatomical correlation of the anterior notches. The aim of this study was to identify and to ...
Blackmer Allison Beck - - 2009
OBJECTIVE: To review the available literature addressing the role of fondaparinux in the management of heparin-induced thrombocytopenia (HIT). DATA SOURCES: Primary articles were identified by a MEDLINE search (2004-June 2009) of English-language literature using the MeSH headings fondaparinux, heparin, low-molecular-weight heparin, and thrombocytopenia. Relevant consensus guidelines (2006-June 2009) were also ...
Noordzij Marlies - - 2009
Systematic reviews and meta-analyses are increasingly popular study designs in clinical research. A systematic review is a summary of the medical literature that uses explicit and reproducible methods for searching the literature and critical appraisal of individual studies; in contrast, a meta-analysis is a mathematical synthesis of the results of ...
Manchikanti Laxmaiah - - 2009
Observational studies provide an important source of information when randomized controlled trials (RCTs) cannot or should not be undertaken, provided that the data are analyzed and interpreted with special attention to bias. Evidence-based medicine (EBM) stresses the examination of evidence from clinical research and describes it as a shift in ...
Batra Pete S - - 2009
OBJECTIVES/HYPOTHESIS: The evidence-based medicine (EBM) schema advocates critical appraisal of the scientific literature for treatment of diseases. The objective of this review was to analyze the role of surgery for symptomatic adult inferior turbinate hypertrophy (ITH) by focusing on the following question: In adults with nasal airway obstruction (NAO) from ...
Wilczynski Nancy L - - 2009
BACKGROUND: Systematic review articles support the advance of science and translation of research evidence into healthcare practice. Inaccurate retrieval from medline could limit access to reviews. OBJECTIVE: To determine the quality of indexing systematic reviews and meta-analyses in medline. METHODS: The Clinical Hedges Database, containing the results of a hand ...
Manheimer Eric E Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD 21207, USA. - - 2009
The Cochrane Collaboration, an international not-for-profit organization that prepares and maintains systematic reviews of randomized trials of health care therapies, has produced reviews summarizing much of the evidence on Traditional Chinese Medicine (TCM). Our objective was to review the evidence base according to Cochrane systematic reviews. In order to detect ...
Dowd Jennifer B - - 2009
The notion that chronic stress contributes to health inequalities by socio-economic status (SES) through physiological wear and tear has received widespread attention. This article reviews the literature testing associations between SES and cortisol, an important biomarker of stress, as well as the summary index of allostatic load (AL). A search ...
Furlan Andrea D - - 2009
STUDY DESIGN: Method guidelines for systematic reviews of trials of treatments for neck and back pain. OBJECTIVE: To help review authors design, conduct and report systematic reviews of trials in this field. SUMMARY OF BACKGROUND DATA: In 1997, the Cochrane Back Review Group published Method Guidelines for Systematic Reviews, which ...
Pagliaro L - - 2010
BACKGROUND: Cochrane systematic reviews are of higher quality than reviews published in scientific journals, yet are used less than other sources for clinical decision-making. AIM: To assess whether the characteristics of the Cochrane systematic reviews can account for their scant use by physicians. MATERIALS AND METHODS: We analysed the 87 ...
Nho Shane J - - 2009
PURPOSE: The purpose of this study was to compare the clinical outcome of single-row (SR) and double-row (DR) suture anchor fixation in arthroscopic rotator cuff repair with a systematic review of the published literature. METHODS: We searched all published literature from January 1966 to December 2008 using Medline, CINAHL (Cumulative ...
Micieli Jonathan A - - 2009
To examine the quality of evidence and the variability in the off-label use of bevacizumab (Avastin; Genentech Inc, South San Francisco, California, USA) in the treatment of retinopathy of prematurity (ROP) and to discuss the implications for the design of future randomized controlled trials. Systematic literature review. A systematic review ...
Barton Christian J - - 2009
Development of patellofemoral pain syndrome (PFPS) is considered to be multifactorial. The aims of this systematic review were to (i) summarise and critique the body of literature addressing kinematic gait characteristics associated with PFPS; and (ii) provide recommendations for future research addressing kinematic gait characteristics associated with PFPS. A comprehensive ...
Glore R J - - 2009
INTRODUCTION: Xerostomia is a common symptom among patients referred to ENT clinics. We present an evidence-based approach in a patient complaining of xerostomia who has not been exposed to radiotherapy. METHOD (search strategy): This review was based on a literature search last performed on 1 July 2008. MEDLINE and EMBASE ...
Berra Bruno - - 2009
In this paper, the link between high glycemic index and load will be reviewed. The data from the literature discussed relate to a short presentation of the physiopathology of acne, including the influence of hyperinsulinemia as a key factor at the beginning of acne.
Faraday Martha - - 2009
The American Urological Association (AUA), as the premier urological organization in the USA, has been a pioneering force in the development of practice guidelines. Recently the AUA evaluated their guidelines development procedures and implemented several changes that resulted in more scientifically rigorous, transparent and efficient processes. These changes include narrowing ...
- - 2009
An increasing number of statistical terms appear in journal articles and it can be difficult to keep abreast of these. With this in mind, DTB is producing a series of short explanatory articles covering various terms and their uses. This, the fifth article in the series, will focus on terms ...
Liberati Alessandro A Università di Modena e Reggio Emilia, Modena, Italy. - - 2009
Systematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safety of health care interventions accurately and reliably. The clarity and transparency of these reports, however, is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, and other users. Since the development ...
Liberati Alessandro A Università di Modena e Reggio Emilia, Modena, Italy. - - 2009
Systematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safety of health care interventions accurately and reliably. The clarity and transparency of these reports, however, is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, and other users.Since the development of ...
Liberati Alessandro A Università di Modena e Reggio Emilia, Modena, Italy. - - 2009
Systematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safety of health care interventions accurately and reliably. The clarity and transparency of these reports, however, is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, and other users. Since the development ...
Lo Scalzo Alessandra - - 2009
OBJECTIVES: The aim of this study was to assess the evidence of diagnostic accuracy of the wireless capsule for endoscopy (WCE) for the diagnosis of obscure gastrointestinal bleeding (OGIB) and small bowel disease in adults and translate it to the context of the Italian National Health Service. METHODS: We performed ...
Kars H J J Cojanne - - 2009
The objective of this review is to identify and review publications describing the impact of reduced somatosensation on balance. Based on knowledge of the association between specific somatosensory loss and deterioration of balance, conclusions can be made about role of somatosensation in standing balance. A systematic literature review is presented ...
Wolfenden L - - 2010
To facilitate the translation of research evidence into practice, policy makers and practitioners require practice-relevant information such as the effectiveness of interventions delivered in specific settings, by various personnel, using various intervention modalities, and descriptions of intervention costs or adverse outcomes. The aim of this study was to review the ...
van der Molen H F - - 2009
OBJECTIVES: The objective of this paper is to describe the main steps and to conduct a systematic literature review on preventive interventions concerning work-related injuries and to illustrate the process. METHODS: Based on the Cochrane handbook, a structured framework of six steps was outlined for the development of a systematic ...
Fitzpatrick D - - 2009
To determine the extent to which post-hypoglycaemic patients with diabetes, who are prescribed oral hypoglycaemic agents (OHA) are at risk of repeat hypoglycaemic events (RHE) after being treated in the prehospital environment and whether they should be transported to hospital regardless of their post-treatment response, a systematic literature review was ...
Horkan L - - 2009
Many systematic reviews have found insufficient evidence to support claims that modern dressings promote healing, or that one particular modern dressing is more effective than another. This paper evaluates why this might be the case.
Ressing Meike - - 2009
Because of the rising number of scientific publications, it is important to have a means of jointly summarizing and assessing different studies on a single topic. Systematic literature reviews, meta-analyses of published data, and meta-analyses of individual data (pooled reanalyses) are now being published with increasing frequency. We here describe ...
Metcalfe David - - 2009
A number of non-operative interventions are used to manage Achilles tendinopathy. In particular, local glucocorticoid injections have generated controversy. Although a number of case reports indicate symptomatic relief following glucocorticoid injection, one systematic review found little evidence to support their efficacy. Furthermore, local glucocorticoid injections may be associated with rupture ...
Carlisle Daloni - - 2009
A number of initiatives proposed in Lord Darzi's next stage review are under way or are in preparation stages, including quality accounts. It is still unclear how far middle managers and clinicians have taken the quality vision on board. Sudden economic downturn has set off a new debate over whether ...
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