Chondrosarcoma of the jaws arises from vestigial rests and is considered a rare entity, although it is more common than its benign counterpart. Occasionally it may be extremely difficult under the microscope to decide whether a case is benign or malignant. The treatment of choice is surgical with wide margins. ...

A single case of symptomatic metastatic melanoma to the gallbladder, with roentgenographic findings of gallbladder disease, is presented. Review of the 12 previously reported cases of symptomatic metastatic biliary melanoma and of those reports of "primary" melanoma of the gallbladder reveals marked similarity between the two groups, with regard to ...

Mucinous tumors of the ovary are incidentally associated with ovarian sarcoma. Several cases of sarcoma-like mural nodules in ovarian mucinous tumors have been described previously, but only two well-documented cases of true sarcoma were reported. The purpose of this article is to report a case of sarcoma occurring in ovarian ...

Histopathologic peer review of specimens from 216 consecutive patients with soft-tissue or bone sarcomas on Southeastern Cancer Study Group protocols was performed by a panel of three pathologists. Subtype of sarcoma, degree of confidence in diagnosis, and grade were compared with agreement or disagreement in pathologic opinion from the primary ...

We report the case of a 74-year-old woman who was admitted to hospital with progressive dysphagia. Further examinations revealed a tumor in the esophagus in which the macroscopic aspect and the histological work-up showed a primary malignant melanoma. The histogenesis of primary malignant melanoma in the esophagus is discussed, and ...

The case is presented of a 54-year-old black man with a mass apparently involving only the soft tissue retromolar trigone on panoramic and mandibular series radiographs. A granulocytic sarcoma involving the mandible was diagnosed on biopsy with the aid of histochemical stains, immunologic cell surface markers, and electron microscopy. The ...

A case of late metastasis of a primary malignant melanoma of the sole of the foot after a disease-free interval of 13 years in a premenopausal woman is presented. The clinicopathologic findings are described, and the literature concerning late metastases (beyond 10 years) of melanoma is reviewed. Only seventeen documented ...

Computed tomography was performed in four patients with osteogenic sarcoma of the nasal cavity and paranasal sinuses. In all cases CT demonstrated an abnormal soft tissue mass with associated aggressive bony destruction. In only one case were areas of calcification and new bone formation identified, allowing a preoperative diagnosis. The ...

Primary laryngeal melanomas (LM) are rare. In a review of all mucosal melanomas of the head and neck (MMHN) at Memorial Hospital from 1949 to 1983 we identified only three such cases. Review of the literature shows that LM usually involve the supraglottic larynx of elderly males. Although survival is ...

The authors report the case of a patient with malignant thymoma unresponsive to combination chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisone [CHOP] and cisplatin/VP-16) who subsequently achieved clinical response to continuous daily prednisone. A review of the literature indicates that prednisone and cisplatin are the most active agents in the treatment ...

Forty-five cases of cardiac angiosarcomas were reviewed, and the data were compared with those of a 1968 review of 41 other cases which revealed these tumors to be typically located within the right atrium as large symptomatic masses and to be rapidly fatal, with the diagnoses usually determined only at ...

Rhabdomyosarcoma is the most common childhood sarcoma, whereas, primary pararectal rhabdomyosarcoma is very rare. To date, four pediatric and eight adult cases have been reported. In children, the tumor presents as a perianal polypoid mass, often initially misdiagnosed. Formerly a very lethal sarcoma, rhabdomyosarcoma is now treated with combined surgery, ...

We report 2 cases of angiosarcoma of the prostate gland. The patients were 42 and 60 years old, which is in sharp contrast to the presentation of rhabdomyosarcoma, which occurs primarily in children. Immunoperoxidase staining for factor VIII associated antigen was positive in both cases, and was particularly useful in ...

The first reported case of an extraosseous osteogenic carcinoma of the parotid gland is presented. The head and neck region is an unusual site for these unusual neoplasms, with approximately 5 per cent of all extraosseous osteogenic sarcomas originating in the soft tissues of the face and neck. The neoplasms ...

Retinoblastoma survivors following successful treatment have a predilection to develop other malignant neoplasms. This report describes a patient with bilateral retinoblastomas diagnosed and treated early in life, who developed cutaneous malignant melanoma 20 years later. In our review of the literature only 5 cases with this association have been reported. ...

A case of malignant mixed mesodermal tumor (MMT) of the uterus in a 4-year-old girl is reported. The patient had a polypoid lesion protruding from the vagina which was initially thought to be a sarcoma botryoides. This is one of the youngest cases of MMT on record. A review of ...

The development of sarcoma within a glioblastoma is a well recognised complication: in the majority of cases it is a fibro-sarcoma originating in the tissues of the proliferating hyperplastic blood vessels. In the case described here the tumour is a rhabdomyosarcoma, apparently derived from abnormal prolific vascular mesenchyme. Only one ...

A rare case of Ewing's sarcoma, originating primarily in the spinal epidural space is reported. Only five similar case reports are available in the English literature. Full recovery from a state of complete paraplegia, due to malignant compression, local recurrence without distant metastases and the longest survival of more than ...

Only two cases of malignant melanoma in childhood have previously been reported in this Journal (Olbourne and Harrison, 1974; Keall et al., 1981). The report describing 31 cases in the Manchester area (Pratt et al., 1981) indicates that this condition may be more common in this country than previously supposed. ...

Malignant melanoma of the oral cavity is rare, accounting for about 1% to 8% of all melanomas. There have been no prospective studies of melanoma in this location, and all previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The authors report ...

A review of eight cases of rhabdomyosarcoma in childhood seen at the Ahmadu Bello University Hospitals in Kaduna and Zaria (Nigeria) over five years is presented. The cases were equally divided between the head region and the urogenital system. Embryonal rhabdomyosarcoma and sarcoma botryoides were the only histologic types seen. ...

A case of rhabdomyosarcomatous adenosarcoma of the uterine cervix is described and the literature reviewed. This variant of adenosarcoma does not appear to be more malignant than other adenosarcomas. It can and should be differentiated from embryonal rhabdomyosarcoma and malignant mixed müllerian tumor because of the different prognostic implications and ...

Five cases of malignant cerebellar astrocytoma observed during a seven-year period are reported. The analysis of the cases allows us to conclude that malignant cerebellar astrocytoma represents a true tumoral entity quite distinct from cerebellar glioblastoma as well as from medulloblastoma. A perfect correspondence between the histological malignancy and the ...

Among the various localizations of primary malignant histiocytoma, the ano-rectal one is exceedingly rare. In this paper we report a case characterized by a storiform-pleomorphic pattern of the tumor and a rapid fatal course of the disease with metastasis in the lungs. The prognostic value of the histologic features is ...

Ewing's sarcoma is a rare primary osseous neoplasm of children and young adults. The use of radiotherapy and adjuvant chemotherapy has favorably influenced the outcome of patients and dramatically reduced the rate of local disease recurrence. However, distant metastasis, usually to the lung and skeletal system, continues to be a ...

Clear-cell sarcoma of tendons and aponeuroses is a rare and slowly growing soft tissue sarcoma, affecting mainly young adults. During the last 15 years, approximately 60 cases have been reported in the literature. In this report, six additional cases followed in the Sarcoma Unit at The Royal Marsden Hospital are ...

Acral lentiginous melanoma has not previously been reported in the English literature. It is a rare tumour occurring nearly always on the palmar and plantar surfaces and has only recently been recognised as a separate histological group of melanoma. Diagnosis can be difficult both clinically and histologically, and is often ...

Malignant mesothelioma is an uncommon, but increasingly important, neoplasm. The existing English-language medical literature concerning non-asbestos-related malignant mesotheliomas was reviewed for evidence of other agents associated with the induction of malignant mesothelioma. Both animal and human data were reviewed. In most reviews of malignant mesothelioma, there are a significant proportion ...

An 8-year-old Taiwanese girl presenting with generalized petechial hemorrhages, severe thrombocytopenia and lymphadenopathy was found to have primary Kaposi's sarcoma of lymph node without cutaneous involvement. This patient is a first-documented case of lymphadenopathic type of Kaposi's sarcoma in Taiwan. The associated severe thrombocytopenia resulting in generalized petechial hemorrhages as ...

The occurrence of synovial sarcoma in sites other than the extremities is rare. Twelve cases in the hypopharynx but none in the esophagus have been described. A case of polypoid synovial sarcoma arising in the upper third of the esophagus in a 25-year-old man is reported. To the authors' knowledge, ...

Hemicorporectomy , or translumbar amputation, is a dramatically drastic surgical salvage procedure for patients with uncontrolled locally extensive pelvic-perineal malignancies. Several successful cases have been reported in the world literature [3-6] and careful perioperative management has been crucial. The case presented is that of a massive recurrent chondrosarcoma of the ...

Oculodermal melanocytosis is a congenital melanoblastic hamartoma affecting ocular tissues and facial skin. It is seen more commonly in oriental and black patients. Malignant degeneration, once believed to be rare in this syndrome, occurs in 4.6% of all reported cases, and is more frequent in whites. The actual incidence of ...

A case of bilateral primary choroidal melanoma is described in a 51-year-old white male. Histological confirmation followed enucleation of the left eye and local excision in the right. A careful systemic evaluation failed to demonstrate any other primary or secondary melanomata. This case is the first bilateral primary choroidal melanoma ...

Two cases of clear cell sarcoma of tendons and aponeuroses, one with prominent melanogenesis, are reported. One tumour arose in the left buttock of a young male and the other in the left fourth toe of a young female. Both had a rapid fatal course with local and distant metastases. ...

A case of malignant melanoma metastatic to the endometrium is presented along with a review of the literature on metastatic melanoma, showing its rarity. Malignant melanoma metastasizes to many sites, including the lung, bone, liver, skin, and pancreas. Four cases of melanoma metastatic to the endometrium have been reported. The ...

Roentgenographic review of the first 210 cases of Ewing sarcoma (ES) in the Intergroup Ewing Sarcoma Study revealed that 37.6% of cases had evidence of diffusely increased intraosseous density or diffuse sclerosis (DS). In these cases the sclerosis was usually mixed with various patterns of lysis and/or combined with a ...

2 cases of laryngeal metastases from malignant melanoma of the skin have been observed at the ENT Department of Padua University during the last 17 years (from January 1966 through December 1982). A critical review of the pertinent literature is made and the metastatic spread to the larynx is also ...

The importance of DIC in the management of gynecological malignancy, especially in advanced cases, was stressed on the basis of our experience with 8 cases. The overall incidence of DIC in our series of 366 cases of gynecological malignancies was 2.2%. However, DIC was experienced only in cases of advanced ...

A case of a 12-year-old girl with Ewing sarcoma of the third metacarpal bone is described. Following an incisional biopsy, radiation therapy and adjuvant chemotherapy were given. The girl is now 34 months postdiagnosis and 25 months off therapy in sustained complete remission and functionally normal right hand. Of the ...

Malignant melanoma can involve any organ of the body and commonly involves the gastrointestinal tract. The first case of melanoma in the world's literature involving the cystic duct and the first in the English literature involving the common bile duct is described. This case is compared with the two cases ...

Four cases of choroidal melanoma with extrascleral extension are presented. In each case, contact B-scan ultrasonography identified extrascleral extension of choroidal melanoma as an area of relative echolucency immediately behind the globe. These ultrasonographic findings are contrasted with those demonstrated by computerized tomography. The importance of B-scan ultrasonography in the ...

The racial and geographical distribution of Kaposi's sarcoma is well recognized. Therefore, a hereditary factor is suspected to play a role in it's etiology. Inspite of this, only about 15 instances of familial cases with the disease have been as yet reported in the literature. We describe here an additional ...

The authors describe the theoretical principles and the experimental and clinical investigations that form the basis for the technique of selective hyperthermic perfusion of the limbs, with or without the addition of antiblastic agents. Neoplastic cells are much more sensitive to heat than normal cells, undergoing necrosis at a temperature ...

We report the second case of a malignant fibrous histiocytoma of the large bowel. The neoplasm constituted an incidental finding during the diagnostic work-up for diverticulitis of the sigmoid colon. There was a massive abdominal recurrence of the tumor four months after colectomy, and the patient died nine months after ...

A case of pigmented purpuric lichenoid dermatitis of Gougerot-Blum is presented and the pertinent literature is reviewed. This case is unusual in that the lesions were unilateral and very limited in extent. The patient presented with a localized pigmented purpuric eruption of plaques on the dorsum of one foot which ...

A fifteen year review (1968-1982) of all cases of malignant melanomas seen in Singapore revealed nine cases in the oral region. The cases were analysed and the literature reviewed. The cases usually presented late and the hard palate is the commonest site involved. The highest incidence is around the 4th-6th ...

In order to obtain an epidemiological picture of occupational pleural malignant mesotheliomas in Japan, the author surveyed the Annual of Pathological Autopsy Cases (published by the Japanese Pathological Society) from 1974 through 1980. Two hundred and twenty-two malignant mesotheliomas (0.114% of all autopsy cases) were found in that period. One ...

From an assessment of the presence of a junctional component in 8,380 pigmented naevi, and histological review of its extent and the presence of inflammation and regression in a sample of 216 junctional and compound naevi, it was determined that naevi excised in summer were more likely to have a ...

An unusual case of angioimmunoblastic lymphadenopathy (AILD) with a rare clinical course and marked gastrointestinal involvement is reported. Two years after the onset of AILD, there was a dramatic alteration in the clinical picture which appeared to take on a malignant course. Despite the clinical course and the presence of ...

Sixteen autopsy cases of the primary sarcomas of the mouth and jaws were reviewed, which included 1 chondrosarcoma, 3 osteosarcomas, 1 leiomyosarcoma, 7 rhabdomyosarcomas and 4 histiocytic lymphoma (reticulum cell sarcoma). Although the case materials studied were too small, the pattern of the spread of the sarcomas of the mouth ...