In a 60-year-old man, a swelling anteromedially just below the knee led to the discovery of an intraosseous leiomyosarcoma. It is the 13th documented case of primary leiomyosarcoma of bone outside the facial skeleton. Clinical and pathologic findings, modes of treatment and therapeutic results are reviewed, and theories of histogenesis ...

An 85-year-old man with unexplained hemorrhagic pseudoascites of four years' duration was discovered to have a primary omental leiomyosarcoma. Neoplasms arising in the greater omentum are rare. To date, only three primary omental leiomyosarcomas have been described. Clinical and pathologic findings of this case are presented and the topic of ...

Duodenal leiomyomas are a very rare cause of upper gastrointestinal bleeding and the disorder is not always diagnosed. The author describes such a case in a 71-year-old woman. It illustrates the problems in diagnosis and describes the appropriate treatment. The pathologist may find it difficult to distinguish between a malignant ...

Sixty-five cases of pulmonary leiomyomas previously have been reported. A new case is reported of a 23-year-old man. Electron microscopy showed typical ultrastructural smooth muscle differentiation. In a series of 66 cases from the world literature, the ratio of females to males was of 1.5:1. There is a slight preponderance ...

A case of multiple pulmonary leiomyomas is presented. In a review of the literature, a confusing array of rare diseases all pertaining to multiple leiomyomas was found. These were reduced to three entities: leiomyomatosis in women, metastatic leiomyoma in men and children, and multiple pulmonary fibroleiomyomatous hamartoma occurring in anyone. ...

Pure rhabdomyosarcomas are extremely rare and lethal primary neoplasms of the ovary. The available literature revealed 14 such cases. This report describes the light and electron microscopic findings of another case. At the electron microscopic level, rhabdomyogenesis recapitulates skeletal muscle differentiation during early fetal life. Rhabdomyoblasts in the ovary may ...

Leiomyoma, a benign neoplasm of smooth muscle cell origin, has been documented infrequently in the oral cavity. It may arise wherever unstriated muscle is present including the arterial wall (Cherrick et al., 1973). The most common site is the uterus, followed by the wall of the alimentary canal and in ...

A case of leiomyosarcoma arising in a preexisting leiomyoma of the broad ligament is presented with ultrastructural and Feulgen microspectrophotometric confirmation. This is the fourth reported case of leiomyosarcoma of the broad ligament and the second reported case to show evidence of a preexisting leiomyoma. Three of these patients died ...

Two benign ovarian cystic teratomas, each containing a partial human body-like structure (homunculus), are described. One was found in a 30-year-old woman, and the second occurred in a prepubertal 10-year-old girl. Each of the 2 homunculi resembled the lower half of a miniature human body with buttocks, a pair of ...

Anterior sacral meningoceles and presacral teratomas are rare congenital malformations associated with a sacrococcygeal bony defect. The inheritance of anterior sacral meningoceles has been proposed to be X-linked dominant, whereas presacral teratomas have been reported to be autosomal dominantly inherited. Anterior meningoceles and teratomas may occur independently or in combination. ...

A case is described of a neuroblastoma which appeared to arise in a mature cystic teratoma of the ovary. The literature concerning neural tumours of the ovary is briefly reviewed and the grounds for believing that the development of such neoplasms is an indication of the presence of immature neuroepithelial ...

A case of thrombosis of superior vena cava in a child with thymoma is reported and the necessity of an exact definition of vascular lesions in thymopathies underlined. The innominate veins and the superior vena cava should be visualized preoperatively to program an appropriate radical surgical treatment particularly when these ...

Gliomatosis peritonei, a rare complication of solid ovarian teratomas, is a miliary, mature glial implantation on the peritoneum or omentum. Two new cases are reported and 30 previously reported cases are reviewed. Gliomatosis peritonei is thought to be benign in almost all cases and thus deserves no treatment except for ...

The clinical presentations, findings of neuroradiological examinations, laboratory findings, pathological diagnoses, methods of treatment, and results of follow-up of 43 cases of pineal tumor collected at the Nagoya University Hospital from 1958 to 1979 are reviewed. The definitions of calcification of the pineal body and of pineal tumor are given. ...

The authors report a case of a male 53 years old with a leiomyoma and a leiomyoblastoma in his stomach. The signs of clinical presentation were given by the leiomyoma. The leiomyoblastoma was a surgical finding. The rarity of the association of these two lesions and the malignant potentiality of ...

Leiomyosarcoma, a highly malignant tumor of the inferior vena cava, is rare. Only 55 cases have been reported in the world literature, and of these only 18 were evaluated with a special vascular procedure, either arteriography or inferior vena cavography. In two cases of leiomyosarcoma of the inferior vena cava, ...

Nongestational, pure ovarian choriocarcinoma is decidedly rare; the unequivocal diagnosis is rarely established in women of childbearing age. Differentiation of nongestational from gestational trophoblastic neoplasia is crucial, the prognosis and therapy being distinct in each type. We report a case of primary ovarian, nongestational, pure choriocarcinoma in a 27-year-old woman ...

Two rare cases of carcinosarcoma of the esophagus are presented. In the first case the decision to operate was based on an initial diagnosis of leiomyosarcoma made by endoscopic biopsy. In the second, a diagnosis of carcinosarcoma was also obtained by endoscopic biopsy. The pathology is commented on. The authors ...

A patient who, eight years prior, had a Heller operation for achalasia developed hypertrophic osteoarthropathy possibly secondary to a leiomyoma of the esophagus with sarcomatous changes. No local invasion or metastases were found. Total esophagectomy completely cured the esophageal symptoms and relieved the swelling and pain of her knees and ...

A case of diffuse leiomyomatosis of the esophagus which was successfully resected is presented. The patient was a 44-year-old man who had an abnormal filling defect, which was incidentally discovered during esophagography, and was observed for two years. Although he remained asymptomatic, an operation was performed because of increase in ...

Leiomyosarcoma of the colon, excluding that of the rectum, is extremely rare. We report a case of leiomyosarcoma of the ascending colon with a brief review of literature. The clinical manifestations in our case were typical: abdominal pain, diarrhea, anorexia, and a palpable tumor that was firm, smooth, and mobile ...

Retroperitoneal teratomas are rare in adults; they are malignant in 25.8% of cases. The authors report two benign cases in which radiologic examination was essential in establishing the diagnosis. Irregular calcifications, which are visible in 61.5% of reported cases, cannot be considered a sign of benignity, since 12.5% of calcified ...

A case of leiomyosarcoma of the inferior vena cava (IVC) is reported. Only 48 cases have been previously reported in the world literature. Pre-operative management is discussed with reference to diagnostic consideration. The case strengthens the concept of operative intervention in asymptomatic abdominal masses with minimal pre-operative workup and delay.

Leiomyomas may originate from any anatomic location of smooth muscle in the genitourinary system but are uncommon neoplasms. Five unusual cases of leiomyomas arising from the renal pelvis, bladder, spermatic cord, and glans penis are presented. The leiomyoma arising from the glans penis in a three-year-old boy is the first ...

Leiomyoma of the urethra is a rare condition, which is more common in female than in male subjects. There are only 14 documented cases of leiomyoma of the female urethra in the literature. A careful analysis of these cases revealed the average patient age to be 34.1 years. The site ...

Fourteen uteri, removed for IUD-associated menorrhagia, were studied. Twelve of these IUD-bearing uteri showed pure diffuse myometrial hypertrophy; the other two uteri were enlarged as a result of multiple leiomyomas in one case and extensive deep adenomyosis in the other. The incidence of pure myometrial hypertrophy in the IUD group ...

Gastric teratoma is a rare benign tumor with a striking male predominance in patients under one year of age. The common presenting features are a palpable mass producing gastro-intestinal hemorrhage or respiratory distress. Approximately 50% of gastric teratomas may show calcification on plain abdominal roentgenograms. Two cases in newborns are ...

A case of primary malignant teratoma of the thyroid in a gravid 37-year-old female is reported and the literature on cervical teratomas in adults reviewed. The patient was treated by total thyroidectomy and left radical neck dissection followed by cervical and mediastinal radiotherapy and chemotherapy. She fied of recurrent tumor ...

Two cases of flow-directed, balloon-tipped catheterizations of the right heart via a persistent left superior vena cava are presented. In both cases, the monitoring catheters assumed similar, atypical configurations on plain chest roentgenograms. Recognition of the characteristic configuration of the course of transvenous catheters through the persistent left superior vena ...

Thirteen cases of leiomyosarcomas of the extremities are reported. Most of the cases were operated on without information concerning benignancy or malignancy. Plain radiographs showed amorphous calcification in two cases. Three cases had angiographic study and all revealed malignant neovascularity. In no literature that we reviewed was angiography mentioned in ...

A case of central leiomyoma of the mandible is reported, along with ultrastructural confirmation of the diagnosis. The pertinent literature is reviewed. It is probable that this lesion arose from the smooth muscle in the walls of blood vessels. To the best of our knowledge, this is only the second ...

Four cases of squamous carcinoma arising in benign cystic teratoma of the ovary are presented, with a detailed correlation of clinical, operative and pathological findings with prognosis. Confinement of tumor to the ovary, with an intact ovarian capsule, is the most important prognostic factor since patients wih extracapsular extension succumb ...

An autopsy case of a 46-year-old woman with primary leiomyosarcoma arising in the pulmonary artery is presented. This case is the first description in Japan and the 10th in the world literature as leiomyosarcoma in this part of the body. An electronmicroscopic observation of the postmortem material was useful to ...

Primary leiomyosarcomas of the lung and trachea are rare tumors. Only five cases have been reported in children (two of a lung, one of a mainstem bronchus, one of the carina, and one of the trachea). We report a new case in a 14-month-old boy and review the previous cases.

Leiomyosarcoma of the inferior vena cava is a rare and usually fatal disease. Only 45 cases have been reported in the world literature. The authors add one case and review all previous reports. The disease is one primarily of elderly women, arising from the middle third of the inferior vena ...

A case of leiomyosarcoma of the nasal cavity and paranasal sinuses is presented along with a review of the medical literature. The clinicopathological aspects of this tumor are discussed. The mode of treatment is complete surgical excision with close follow-up due to its high rate of local recurrence. The long-term ...

A 25-year-old woman presented with a giant leiomyoma in the lower third of the esophagus. She had no digestive symptoms, although there was a severe esophageal dilation. Such a megaesophagus secondary to a leiomyoma has not been described previously. Esophagogastric resection was performed, followed by an uneventful recovery period. The ...

Two cases of primary hepatic leiomyosarcoma are reported. Review of the literature reveals only seven previous reports. Cases presented predominantly with either hepatomegaly or ascites. Neither history nor physical and laboratory examination distinguished these patients with primary leiomyosarcomas from those with other hepatic tumors. Analysis of the cases reviewed suggests ...

This paper documents three cases of benign cystic ovarian teratoma in which elements of adenohypophysis was recognized as one of the tissue components. Such findings have been recorded but not unequivocally documented in any of the previous reports of benign cystic teratomas. One of the tumors in this series also ...