Search Results
Results 1 - 50 of 645
1 2 3 4 5 6 7 8 9 10 >
Ballester Sánchez R R Servicio de Dermatología, Hospital Universitario y Politécnico La Fe, Valencia, España. Electronic address: - - 2014
Mucosal melanoma is a rare melanoma subtype that differs from the cutaneous form of the tumor in its biology, clinical manifestations, and management. Diagnosis is usually late due to a lack of early or specific signs and the location of lesions in areas that are difficult to access on physical ...
Razmpoosh Maryam M From the Department of - - 2014
To study and compare the effectiveness of p16(INK4a) staining and specific human papillomavirus (HPV) subtypes as a prognostic marker in cervical intraepithelial neoplasia grade 1 (CIN1; low-grade squamous intraepithelial lesions). Sixty-four cervical samples diagnosed as CIN1 and stained with p16(INK4a), with HPV status assessed by polymerase chain reaction-direct sequencing. Of ...
Hikawa Renato Shintani RS Universidade Federal de São Paulo, São Paulo, SP, - - 2014
Melanoma is a malignant melanocytic neoplasm with high mortality rate, and steadily and universally increasing incidence rates. Polypoid melanoma is considered an exophytic variant of the nodular subtype. The incidence of polypoid melanoma is extremely variable, most likely because of the different criteria used for its characterization. We presented a ...
Calisir Cuneyt C Department of Radiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey, - - 2014
Fibro-osseous pseudotumor (FOPT) is a rare and benign ossifying lesion. Described as the superficial variant of myositis ossificans (MO), this rare entity mostly occurs in the subcutaneous tissues of the digits. The FOPT clinicopathological features may mimic a variety of benign and malignant soft tissue lesions, and the diagnosis can ...
Roda Dominic J DJ a Roger Williams Medical Center, - - 2014
Abstract Merkel Cell Carcinoma is a rare, often fatal, neuroendocrine cutaneous malignancy with a highly variable clinical presentation. Due to the rapid progression of the disease, early detection and treatment is vital in survival rates. Here, we report on the case of a 45 year old female whose podiatrist noticed ...
Alvarez-Larrán Alberto A Department of Haematology, Hospital del Mar, IMIM, Universitat Autònoma de Barcelona, Barcelona, - - 2014
Bone marrow histology is included in the diagnostic criteria of myeloproliferative neoplasms (MPNs). However, some concerns have emerged about its reproducibility. To evaluate the diagnostic accuracy of histology and to assess its correlation with presence of mutations and clinical outcomes, two pathologists reviewed the bone marrow biopsies corresponding to 211 ...
Torres Diogo D University of Louisville, Louisville, KY, USA - - 2014
Extrauterine adenomyomas are extremely rare benign tumors of smooth muscles, endometrial glands, and endometrial stroma. Ectopic endometrial glands can undergo malignant change. The ovary is the most common site of malignant change in endometriosis. Cancer arising in extraovarian endometriosis is a rare event with limited cases in the literature. To ...
Lacruz Goretti G Melanoma Unit, Dermatology Department, Hospital Clínic of Barcelona, IDIBAPS, Barcelona, - - 2014
Background: Acral melanoma (AM) is still one of the most poorly studied melanomas. It generally presents beyond the fifth decade of life and usually is a BRAF wild-type melanoma. Objective: To report the first cases of multiple primary AM in Caucasians. Methods: Clinical, dermoscopic, pathological and molecular profiles. Results: A ...
Pleyer C C Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, - - 2014
There is symptom overlap between gastro-esophageal reflux disease (GERD) and functional dyspepsia (FD). We aimed to test the hypothesis that FD cases are now more likely mislabeled as GERD. In subjects from Olmsted County, MN seen at Mayo Clinic: (i) Investigation of GERD and FD diagnosis rates between 1985 and ...
Floriano Isabela I Department of Pediatric Dentistry, School of Dentistry, Universidade de São Paulo, São Paulo, - - 2014
We assessed association between active caries lesions assessed by two different criteria and clinical features of these caries lesions. Three examiners examined forty-nine 3-12-year-old children: one examiner used the Nyvad criteria, another examiner used the International Caries Detection and Assessment Criteria with an additional criteria - Lesion Activity Assessment (ICDAS+LAA) ...
Ton Nu Tuyet Nhung TN Department of Pathology, McGill University Health Center and McGill University, Montreal, Quebec, - - 2014
The terminology used in reporting urine cytology lacks uniformity and the significance of the "atypical" and "suspicious" categories is still not well established. This results in variable clinical follow-up and management of those cases. The authors sought to investigate the prognostic value of a diagnosis of "suspicious for high-grade urothelial ...
Cabay Robert J RJ From the Department of Pathology, College of Medicine, and the Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois Hospital & Health Sciences System, Chicago, - - 2014
Context.- Some dental abnormalities have environmental causes. Other odontogenic alterations are idiopathic and may have hereditary etiologies. Investigations of these conditions are ongoing. Objective.- -To provide a discussion of developmental odontogenic abnormalities and benign odontogenic overgrowths and neoplasms for which genetic alterations have been well demonstrated and well documented. Data ...
Wang Yen Tun YT *Division of Dermatology, Ronald Reagan UCLA Medical Center, Los Angeles, CA; and †Department of Pathology and Laboratory Medicine, Ronald Reagan UCLA Medical Center, Los Angeles, - - 2014
: Although approximately 876,000 individuals in the United States currently have a diagnosis of melanoma, the Touton-like giant cell variant has been described only twice in the literature to date. In our case, a 70-year-old man with a history of sclerosing carcinoma on the scalp presented for evaluation of a ...
Smith Lauren A - - 2014
Rosacea fulminans, previously known as pyoderma faciale, is a rare disease occurring almost exclusively in young women characterized by the sudden eruption of coalescing papules and pustules, and large cystic nodules limited to the face. Patients generally respond well to standard therapy consisting of systemic isotretinoin in combination with topical ...
Alves João Vítor Pina JV Hospital Garcia de Orta, Almada, - - 2014
Several variants of dermatofibroma have been described. They are essentially distinguished by their clinical and histopathological features. To review the mainfeaturesof these variants, a retrospective study of skin biopsies and tissue excisions of dermatofibromasperformed in the dermatology and venereology service at the Hospital Garcia de Orta between May 2007 and ...
Shah Azhar Ali AA Department of Surgery, Ghulam Muhammad Mahar Medical College, - - 2014
Endometriosis is the condition where endometrium gets implanted and flourishes outside the uterine cavity, most commonly in ovary and on the peritoneum which lines the abdominal cavity and viscera. Endometrial cells in areas outside the uterus are influenced by hormonal changes and respond in a way similar to the endometrium ...
Ariyawardana Anura A School of Medicine and Dentistry, James Cook University, McGregor Road, Smithfield, QLD 4878, Australia, Tel: +647-4232-1248; e-mail: - - 2014
Oral mucosal lesions are a common occurrence and very often dentists are called upon to see such patients. Among many causes trauma is one of the leading for oral mucosal diseases. Oral traumatic lesions are diverse in which some present as acute lesions while the majority are chronic lesions. Clinical ...
Frank Paul N PN Section of Endocrine Surgery, Department of Surgery, David Geffen School of Medicine, University of California, Los - - 2014
IMPORTANCE Benign granulomatous disease may mimic malignant disease in the evaluation of mediastinal or pulmonary lesions. However, histoplasmosis as a cause of cervical lymphadenopathy is relatively rare. We report the first case of Histoplasma infection mimicking malignant adenopathy discovered during diagnostic thyroid lobectomy. OBSERVATIONS A 2.5-cm, calcified, right paratracheal lymph ...
Romanoff Anya M AM Department of Surgery, Dubin Breast Center, Mount Sinai Medical Center, New York, NY, USA, - - 2014
Breast pathology is a challenging field, and previous work has shown discrepancies in diagnoses, even among experts. We set out to determine whether mandatory pathology review changes the diagnosis or surgical management of breast disease. Cases were referred for pathology review after patients presented for surgical opinion to the Dubin ...
Le Mercier Marie M Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), Brussels, - - 2014
The assessment of thyroid nodules is a common clinical challenge. Fine-needle aspiration (FNA) is the standard preoperative tool for thyroid nodule diagnosis. However, up to 30% of the samples are classified as indeterminate. This often leads to unnecessary surgeries. In this study, we evaluated the added value of next-generation sequencing ...
Gaeti João Guilherme L N JG Laboratory of Veterinary Pathology, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa 2367, Cuiabá, Mato Grosso, CEP 78069-900, - - 2014
Ureaplasma diversum has been associated with various reproductive problems in cattle that include granular vulvovaginitis, weak calves, and abortion. This study was conducted in a beef herd situated in the Middle-West region of Brazil, and the objectives were to verify the presence of U. diversum and to elucidate its possible ...
Beaudenon-Huibregtse Sylvie S Asuragen Inc., Austin, Texas, United States ; - - 2014
<b><i>Background:</b></i> Molecular testing for oncogenic gene mutations and chromosomal rearrangements plays a growing role in the optimal management of thyroid nodules, yet lacks standardized testing modalities and systematic validation data. Our objective was to assess the performance of molecular cytology on preoperative thyroid nodule fine needle aspirates (FNAs) across a ...
Kono Yoshiyasu Y Yoshiyasu Kono, Yasushi Yamasaki, Kazuhide Yamamoto, Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, - - 2014
To investigate the usefulness of chromoendoscopy, using an acetic acid indigocarmine mixture (AIM), for gastric adenoma diagnosed by forceps biopsy. A total of 54 lesions in 45 patients diagnosed as gastric adenoma by forceps biopsy were prospectively enrolled in this study and treated by endoscopic submucosal dissection (ESD) between January ...
Burciu Roxana Gabriela RG Department of Neurology, University Clinic Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany, - - 2014
Studies of cerebellar patients employing modern lesion-symptom mapping techniques have provided valuable insights into the contribution of the cerebellum to motor adaptation. In patients with chronic focal lesions of the cerebellum, the process of adapting reaching movements to force field (FF) and visuomotor rotation (VM) perturbations relies on different anatomical ...
Mooi Wolter J WJ Department of Pathology, VU University Medical Center Amsterdam, Amsterdam, The - - 2014
On the basis of a critical review of published literature, it is concluded that there is as yet insufficient evidence to conclude that the melanocytic lesion, which is currently known as "lentiginous melanoma," is a full-fledged melanoma, with the capacity to metastasize to distant sites and to cause the demise ...
Argenziano Giuseppe G Skin Cancer Unit, Arcispedale Santa Maria Nuova IRCCS, Reggio, Emilia, - - 2014
The development of new primary melanomas in patients treated with vemurafenib has been reported recently in a study by Perier-Muzet et al. The primary outcome of the study was to describe the dermoscopic changes that prompted excision of those melanomas. However, the crucial point raised by the study is the ...
Slade Austen D AD aDepartment of Pediatric Surgery, The University of Texas Medical School at Houston bDepartment of Pediatrics, Children's Cancer Hospital, The University of Texas M.D. Anderson Cancer Center cDepartment of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, - - 2014
To inform pediatricians of the challenges of detection of melanoma in children and adolescents as well as to instruct on proper biopsy technique of suspicious lesions. The incidence of melanoma in children and adolescents is on the rise with an average increase of 2% per year. Rates of change are ...
Bhushan Nvv Satya NS Professor, Department of Oral and Maxillofacial Surgery, GITAM Dental College and Hospital , Vishakhapatnam, India - - 2014
We are reporting a case of an ameloblastoma which arose in the wall of a dentigerous cyst. The clinical, radiographic and histological characteristics were similar to those of dentigerous cysts, as were seen on doing an incisional biopsy. Enucleation was done intraorally under local anaesthesia. Post-operative excisional biopsy revealed strands ...
Dewitt John M JM Division of Gastroenterology and Hepatology, Indiana University Medical Center, Indianapolis, Indiana, - - 2014
Background and study aims: Endoscopic ultrasound (EUS)-guided ethanol lavage with paclitaxel injection has been shown to be effective for the treatment of pancreatic cystic neoplasms; however, the evidence for effectiveness is based primarily on cyst resolution on imaging. The aim of this study was to evaluate changes in pancreatic cyst ...
Niebling Maarten G MG Melanoma Institute Australia, Sydney, NSW, - - 2014
Pathologists sometimes disagree on the diagnosis of melanoma or its histopathologic staging, which may have implications for treatment and follow-up. For this reason, melanoma patients referred to Melanoma Institute Australia (MIA) for further treatment routinely have their pathology slides reviewed by MIA pathologists. This study sought to determine whether diagnosis, ...
Wall James J aDivision of Pediatric Surgery, Lucile Packard Children's Hospital, Stanford University, Palo Alto, California bPediatric Pulmonary Division, Department of Pediatrics, Tufts University School of Medicine, Boston, Massachusetts, - - 2014
Congenital lung malformations (CLMs) vary in their clinical presentation and severity. Increases in prenatal diagnosis, observed regression of certain lesions, and prognostic uncertainty are driving an evolution in management. There has been an increase in the early diagnosis of these malformations, a change that is attributable to the routine use ...
Bouillet Laurence L National Reference Centre for Angioedema (CREAK), Internal medicine department, Grenoble University Hospital, BP 217 38043 Grenoble cedex 09 France, Unité Inserm 1036, CEA, Université de médecine Joseph-Fourier, Grenoble, - - 2014
The aetiologies of recurrent angioedema (AE) comprise the frequent histaminergic AE and the rare bradykinin-mediated AE. Diagnosis must be done carefully because they do not have the same treatment. Diagnosis strategy is clinical. The most specific symptoms for bradykinin AE are: isolated AE without wheals, long duration of the attack, ...
Xing Yanfen Y Department of Radiology, People's Hospital of LaiWu - - 2014
Recent studies have revealed a potential relationship between the presence of ground glass opacity (GGO) on regular computerized tomography(CT) and adenocarcinomas. To investigate features of pre-invasive lung adenocarcinoma lesions on thin-section computerized tomography (CT). We evaluated 59 cases of atypical adenomatous hyperplasia (AAH) and 35 cases of adenoma in situ ...
Nguyen T T Houston VA HSR&D Center of Excellence, Baylor College of Medicine, Houston, Texas, USA; Department of Medicine, Baylor College of Medicine, Houston, Texas, - - 2014
Few studies have examined the temporal trends of length in newly diagnosed Barrett's esophagus (BE) and arrived at conflicting results. The aim of this study was to identify whether there has been a change over time in the length of BE at the time of diagnosis. This is a retrospective, ...
Kim J S JS Department of Dermatology, Hanyang University Guri Hospital, Guri, - - 2014
Lipomembranous changes are distinctive histopathological findings, which include the presence of cystic cavities lined by crenulated, hyaline membranes in adipose tissue. It is likely that ischaemia is fundamental to the development of these lesions, and that lipomembranes are formed from the products of degenerating fat cell membranes by some unknown ...
Sinnya Sudipta S Dermatology Research Centre, School of Medicine, University of Queensland, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Queensland, - - 2014
We present a case of verruciform xanthoma ((VX) of the penis in an elderly man in whom an asymptomatic papule on his foreskin was noted during a routine clinical examination. VX is a rare, benign condition with a predilection for the oral cavity and clinically presents as isolated, painless mucosal ...
Franco Joanna Pimenta de Araujo JP State of Rio de Janeiro Federal University, Rio de Janeiro, RJ, - - 2014
Dermatofibrosarcoma protuberans is a fibrohistiocytic tumor of intermediate malignancy with aggressive localized growth, high recurrence rate, but low metastatic potential. It appears as a hardened plaque, with slow growth, upon which the development of nodules occurs. It predominates in the trunk and is unusual in acral locations. Histopathology reveals spindle ...
Kim Jung Eun JE Department of Dermatology, St. Paul's Hospital, School of Medicine, The Catholic University of Korea, Seoul, - - 2014
Congenital self-healing reticulohistiocytosis (CSHRH) is a rare, cutaneous, self-limited form of Langerhans cell histiocytosis. Whereas multiple lesions are common, a solitary lesion is rare. A 14-day-old neonate presented with a solitary, 5-mm, oval, reddish, and eroded papule with crust on the left thigh that had existed since birth. No systemic ...
Rastogi Sanjeev S Department of Pancha Karma, State Ayurvedic College and Hospital, Lucknow University, Lucknow, Uttar Pradesh, - - 2014
Nevus of Ota is a congenital blue-gray color nevus afflicting unilaterally, the area near the eyes. It poses a huge cosmetic concern besides being a potential threat for developing melanoma sometime in the course of the disease. The treatment options are neither many nor promising besides they are too expensive. ...
Maity Ipsita I Department of Conservative Dentistry and Endodontics, GNIDSR, Kolkata, West Bengal, - - 2014
The aim of this study was to assess the outcome of single sitting root canal treatment (RCT) of asymptomatic teeth with periapical cysts. Ten maxillary anterior teeth showing periapical lesion on the radiograph was further screened by ultrasound with color power Doppler (CPD) for confirmation of a cyst. The average ...
Webber Liana Preto LP Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, - - 2014
Paracoccidioidomycosis (PCM) is a deep mycosis with primary lung manifestations that may present cutaneous and oral lesions. Oral lesions mimic other infectious diseases or even squamous cell carcinoma, clinically and microscopically. Sometimes, the dentist is the first to detect the disease, because lung lesions are asymptomatic, or even misdiagnosed. An ...
Dodd Leslie G LG Department of Pathology, University of North Carolina at Chapel Hill, North - - 2014
Pleomorphic liposarcoma represents one of the rarest variants of liposarcoma. It has a poor prognosis and unlike other variants of liposarcoma, lacks a molecular or genetic signature. Histologic studies of pleomorphic liposarcoma have defined this lesion as a high grade sarcoma, which contains a variable number of lipoblasts. We describe ...
Li Yun-Hong YH Yun-Hong Li, Xu Li, Xiao-Ping Zou, Department of Gastroenterology, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu Province, - - 2014
Primary malignant melanoma of the esophagus (PMME) is a malignant tumor which occurs in the melanin cells of esophageal mucosal epithelial basal layer. PMME is a rare disease with an extremely poor prognosis. PMME represents only 0.1% to 0.2% of all esophageal malignant tumors. Dysphagia, retrosternal or epigastric discomfort or ...
Park Hyo Jin HJ Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Gyeonggi, - - 2014
"Atypia of undetermined significance" (AUS) in the Bethesda System for Reporting Thyroid Cytopathology is a heterogeneous category for cases that cannot be easily classified into benign, suspicious, or malignant. This study evaluated whether cytomorphology-based subcategorization could better predict the malignancy risk in cases designated as AUS, and how the subcategories ...
Bohman Summer L SL Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, United - - 2014
Angiomatoid fibrous histiocytoma, a fibrohistiocytic tumour of intermediate malignancy that usually presents on extremities of young patients, has a broader clinical/histological spectrum than is widely appreciated. We summarise our experience with an emphasis on unusual features.Twenty-seven cases were analysed for clinical and histological features, including immunohistochemistry and FISH for rearrangements ...
Hobbs Hasan A HA 1 Department of Radiology, Division of Neuroradiology, Duke University Medical Center, DUMC Box 3808, Durham, NC - - 2014
OBJECTIVE. The Society of Radiologists in Ultrasound (SRU) recommendations on thyroid nodules are intended to "diagnose thyroid cancers that have reached clinical significance, while avoiding unnecessary tests and surgery in patients with benign nodules." The aim of our study was to determine the proportion of thyroid nodules undergoing ultrasound-guided fine-needle ...
Andreassi Lucio L Professor Emeritus, University of Siena, Italy. Electronic address: - - 2014
The genitalia may be the site of non-infectious inflammatory lesions that are generally manifested as balanoposthitis and vulvovaginitis. In men, these forms constitute 50% of all balanoposthitis forms, and in women, vulvovaginitis frequency is even higher. They consist of genital locations of general skin diseases, such as psoriasis, lichen planus, ...
Panwar Aru A Division of Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, - - 2014
Premalignant lesions of the oral cavity present as visibly abnormal areas of mucosa and may be a source of significant anxiety for the patient and the clinician. Suspicious lesions should be biopsied to evaluate for dysplasia. The risk of malignant transformation may relate to patient characteristics, environmental risk factors and ...
An Jingang J From the Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Peking University, Beijing, People's Republic of - - 2014
Surgical ciliated cysts are an uncommon complication of maxillary surgery. We report a case of such a cyst that developed at the right medial canthal region 10 years after the surgical treatment of a severe midfacial fracture. The cyst presented as a round cystic lesion protruding through a small bony ...
Verma Prashant P Department of Dermatology and STD, University College of Medical Sciences (University of Delhi) and Associated Guru Teg Bahadur Hospital, Delhi, - - 2014
Tumid lupus erythematosus (LE) is a rare variant of lupus erythematosus, which often follows a favorable course. A case of a young woman is illustrated, who presented with an asymptomatic erythematous, solitary plaque over her face. Histopathological and direct immunofluorescence examination established a diagnosis of tumid lupus erythematosus. She responded ...
1 2 3 4 5 6 7 8 9 10 >