Search Results
Results 351 - 400 of 797
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Moon Won-Jin - - 2012
The objective of our study was to evaluate the relationships between BRAF mutation status, sonography findings, and fine-needle aspiration cytology features in patients with papillary thyroid carcinoma (PTC) and to evaluate the diagnostic merits of BRAF mutation status and sonography findings as adjuncts to cytologic diagnoses. From March 2006 through ...
Popoveniuc Geanina - - 2012
Thyroid nodules are common entities, clinically important primarily because of their malignant potential. Serum thyrotropin and thyroid ultrasonography are pivotal in evaluating thyroid nodules. Fine-needle aspiration biopsy is the most accurate tool for diagnosing malignancy and selecting candidates for surgery. An approach to the initial evaluation and management of single ...
Lebecque O - - 2012
An apparently healthy 31-year-old man presented with dysphonia. Laryngoscopy revealed a mass at the right side of epiglottis. He underwent a CT examination after intravenous injection of a iodinated contrast agent and this showed the presence of a paralaryngeal mass with rim enhancement. The diagnosis of laryngopyocele was made. Treatment ...
Dar Rayees Ahmad - - 2012
Hashimoto's thyroiditis (HT), an autoimmune disorder, is the most prevalent cause of subclinical or overt hypothyroidism in areas with sufficient iodine intake. The gland is often diffusely enlarged, and the parenchyma is coarsened, hypoechoic, and often hypervascular on ultrasonograpy. Histopathologic appearance of HT includes lymphocyte aggregates with germinal centers, small ...
Barresi Valeria - - 2012
Neutrophil gelatinase-associated lipocalin (NGAL) is a protein which participates in iron trafficking and which is involved in cancerogenesis and cancer progression. Since its over-expression has been documented in thyroid malignancies in comparison to thyroid normal gland, in the present study, we aimed to determine whether the evaluation of NGAL immunoexpression ...
Mahajan A - - 2012
A. Mahajan, X. Lin and R. Nayar Thyroid Bethesda reporting category, 'suspicious for papillary thyroid carcinoma', pitfalls and clues to optimize the use of this category Objective:  The Bethesda System of Reporting Thyroid Cytopathology classifies the indeterminate categories based on their differing risks of malignancy, as atypia of undetermined significance ...
Cantisani Vito - - 2012
PURPOSE: To assess the clinical value of quantitative elastosonography compared with multiparametric ultrasound in differentiating the nature of thyroid nodules. METHODS AND MATERIALS: Ninety-seven consecutive patients (32 males, 65 females, mean age, 54 years, range 20-81 years) with thyroid nodules previously detected at color-Doppler ultrasound (CDUS), were prospectively examined with ...
Johnson Rebecca L - - 2012
We present an interesting case report from a patient with a history of desmoplastic malignant melanoma (MM), who presented with a thyroid nodule. The patient's clinical diagnosis included a benign thyroid nodule versus a primary thyroid malignancy or metastatic MM. Fine-needle aspiration biopsy showed highly atypical spindle cells suspicious for ...
Kim Dae-Weung - - 2012
In evaluating cervical lymph node (LN) metastasis from papillary thyroid cancer (PTC), ultrasonography (US)-guided fine-needle aspiration biopsy (FNAB) is very important tool. There were limited number of studies about the diagnostic value of thyroglubion measurement in FNAB (FNAB-Tg) in non-thyroidectomized patients. Therefore, in this study, the authors evaluated the role ...
Klubo-Gwiezdzinska Joanna - - 2012
This review presents current knowledge about the thyroid emergencies known as myxedema coma and thyrotoxic storm. Understanding the pathogenesis of these conditions, appropriate recognition of the clinical signs and symptoms, and their prompt and accurate diagnosis and treatment are crucial in optimizing survival.
Nagarajah James - - 2012
Background: FNAB is a simple technique for the investigation of suspicious thyroid nodules. However, low success rates are reported in the literature. The aim of this prospective study was to compare the clinical performance and impact of an automatic aspirator to those of the manual technique for the fine-needle aspiration ...
Hryhorczuk Anastasia L - - 2012
The objective of this study was to determine the rate of malignancy in thyroid nodules with an initial nondiagnostic fine needle aspiration. From October 2001 to April 2007, biopsies were performed on 1344 thyroid nodules in our practice. Biopsies were performed on nodules using 25-27 gauge needles, ultrasound guidance and ...
Moon Hee Jung - - 2012
The aim was to compare the diagnostic performances of physicians with different levels of experience for completing preoperative staging ultrasonography (US) for thyroid malignancy. From March 2009 to December 2009, 1421 patients underwent preoperative staging US by six physicians according to the sixth edition of TNM classification. Extrathyroidal extension was ...
Nemec Ursula - - 2012
OBJECTIVES: To investigate the diagnostic accuracy, through quantitative analysis, of contrast-enhanced ultrasound (CEUS), using a microbubble contrast agent, in the differentiation of thyroid nodules. METHODS: This prospective study enrolled 46 patients with solitary, scintigraphically non-functional thyroid nodules. These patients were scheduled for surgery and underwent preoperative CEUS with pulse-inversion harmonic ...
Pagano L - - 2012
Differentiated thyroid cancer (DTC) is an important clinical entity in our population (Novara, Piedmont, Italy) which is characterized by important environmental influences, as iodine deficiency (ID) and subsequent supplementation, thyroiditis and occupational exposure. To evaluate the features of DTC in our population 20 years after the iodine-prophylaxis pondering the effects of ...
Chung Alice Y - - 2012
Although clinically evident metastases of nonthyroid malignancies (NTMs) to the thyroid gland are uncommon, it is important to suspect them in patients who present with a new thyroid mass and a history, however far back, of prior malignancy. In fact, metastases from NTMs to the thyroid gland have been reported ...
Na Dong Gyu - - 2012
Background: Thyroid nodules with fine-needle aspiration (FNA) readings of nondiagnostic or atypia of undetermined significance (AUS), also referred to as follicular lesion of undetermined significance (FLUS) are problematic for their optimal management. The usefulness of performing a core-needle biopsy (CNB) to clarify whether these nodules are benign or malignant has ...
Boeckmann Jacob - - 2012
Objectives. To determine if standardized uptake values (SUV) on positron emission tomography (PET) are predictive of thyroid pathology and the significance of serial SUV measurements of thyroid nodules over time.Study Design. Case series with chart review.Setting. Academic health center.Subjects. In total, 23,384 PET and PET/computed tomography (CT) scans were performed ...
Kim D W - - 2012
BACKGROUND AND PURPOSE:The ability of US to differentiate benign thyroid nodules from malignant ones is still a matter of debate. The aim of this study was to assess the diagnostic efficacy of a US-based classification system for solid and PCTNs through a prospectively designed study.MATERIALS AND METHODS:We studied 1289 thyroid ...
Bonabi Sharouz - - 2012
To evaluate the prevalence of thyroid FDG-PET/CT incidentalomas and the risk of malignancy in focal findings. A retrospective study of 3,062 PET scans was performed between 05/2006 and 09/2009. Prevalence of thyroid incidentalomas, risk of malignancy and correlation between standard uptake value (SUV) and cancer risk were analysed. The overall ...
Al-Shraim Mubarak M - - 2012
To determine the rates of malignancy of thyroid nodules in each standard cytologic diagnostic category of the Bethesda system. In a retrospective cohort study from October 1998 to April 2007 at the Department of Pathology, Aseer Central Hospital, Southwestern region of Saudi Arabia, all cases of thyroid nodules that underwent ...
Kang Min-Hee - - 2012
A 12-year-old intact female shih tzu dog was diagnosed with an ectopic thyroid carcinoma infiltrating the right atrium of the heart. Echocardiography and computed tomography were helpful in diagnosis; a definitive diagnosis was made based on postmortem histopathology and immunohistochemistry. The patient lived 428 days beyond diagnosis with only medical ...
Prasad Nijaguna B - - 2012
The preoperative diagnosis of thyroid nodules primarily depends upon fine needle aspiration (FNA) cytology. However, up to 25% of FNA samples have associated "suspicious or indeterminate", but not diagnostic cytologic reports, resulting in difficulty deciding appropriate clinical management for these patients. We hypothesize that the use of molecular markers as ...
Yu Xiao-Min - - 2012
BACKGROUND: The goal of this study was to determine whether sampling error was the major cause for false-negative fine needle aspiration (FNA) results for thyroid nodules. METHODS: Patients who underwent preoperative FNA between 1994 and 2008 were identified, and the results were compared with surgical pathology findings. Other related variables ...
Peppa Melpomeni - - 2012
Primary thyroid lymphoma is a rare malignancy, representing 2-8% of all thyroid malignancies and 1-2% of all extranodal lymphomas. The majority of cases concern non-Hodgkin's lymphoma of B cell origin, following by Hodgkin's disease, T cell lymphomas and rarely marginal zone B-cell mucosa-associated lymphoid tissue (MALT) lymphomas. MALT lymphomas have ...
Izumi Junichi - - 2012
We report two cases of spontaneous bladder rupture. Preoperative diagnosis was difficult and the correct diagnosis was made at surgery. Reviewing the initial abdominopelvic CT of our second patient, the bladder wall defect and blood attenuation near the bladder were observed. These findings were consistent with the operative findings, and ...
Schrey Susanne - - 2012
OBJECTIVES: To evaluate fetal thoraco-amniotic shunting for isolated large macrocystic cystic adenomatoid malformations (CCAM) of the lung. METHODS: Retrospective study of 11 fetuses with macrocystic CCAM's, who underwent thoraco-amniotic shunting. RESULTS: Shunts were inserted at 24.6 (17-32) wks. Marked mediastinal shift was present in all cases. Six were hydropic, and ...
Kumar Piyush P Katihar Medical College and - - 2012
A 20 years-old girl presented with multiple asymptomatic reddish vesicles on face for four years. It used to get worse in summer and was associated with localized hyperhidrosis. The lesions were notable for disappearance on diascopy. Histopathology from the vesicle showed mononuclear cell infiltration in the upper dermis, especially around ...
Mansor Mona - - 2012
Background. Ultrasonography is considered useful to distinguish between solid and cystic thyroid nodules and to stratify a nodule's risk of cancer as low, medium, or high. Ultrasound (US) elastography has been applied to study the hardness/elasticity of nodules to differentiate malignant from benign lesions. Elastography possibly can solve the dilemma ...
Sokouti Mohsen M Department of Cardiothoracic Surgery, Tabriz University of Medical Sciences, Tabriz, - - 2012
Pericardial cysts are rare congenital abnormalities with a reported incidence rate of 1/100,000 males. The most common locations of these cysts are middle mediastinum and right cardiophrenic angle. Pericardial cysts are usually asymptomatic unless a complication or rapid growth occurs. Diagnosis is generally made incidentally or using combined radiological X-ray, ...
Yamada Hiroya H Department of Laboratory Medicine, Osaka University Graduate School of Medicine, Suita 565-0871, - - 2012
Measurement of gene expression levels in thyroid tumor cells in aspirates was difficult because it is interfered with peripheral blood cells or infiltrating lymphocytes. In this study, we established a novel method to separate thyroid tumor cells from blood cells efficiently with mesh filtration. The expression level of trefoil factor ...
Vinayak Sudhir S Department of Radiology, Aga Khan University Hospital, Nairobi, - - 2012
The objective of this study was to describe a reliable ultrasound based index scoring system based on ultraound characteristics to identify benign thyroid nodules and avoid unnecessary fine needle aspiration cytology. Patients undergoing ultrasound-guided fine-needle aspiration cytology (FNAC) for thyroid nodules were evaluated prospectively. A total of 284 patients were ...
Kutun Suat - - 2012
Introduction: We aimed to determine whether levels of thyroglobulin measured in blood from the inferior-superior thyroid veins and the peripheral antecubital vein could predict the presence of thyroid carcinoma in patients undergoing surgery for thyroid diseases. Material and methods: Sixty-one patients were prospectively enrolled in the study. Levels of thyroglobulin ...
Archuletta Pamela Anne - - 2012
It has been reported that African-Americans (AA) have a higher prevalence of overall malignancy compared to Caucasians, in the United States, yet the incidence of thyroid malignancy is half. The aim of this study is to assess the rate of malignant versus benign thyroid disease in AA from an urban-based ...
Pasricha Sunil - - 2012
Thyroid gland is an uncommon site of tumor metastasis inspite of rich vascular supply. Most of the cases are picked up after the diagnosis or during the work up for the primary. Unexpected involvement of thyroid gland as the first presenting sign in a primary lung adenocarcinoma is an extremely ...
Barrera Jerome Rebollos JR Department of Medicine, Philippine General Hospital, Manila, Philippines. - - 2012
Malignant transformation of benign monodermal teratoma is a rare presentation of struma ovarii. A 41-year-old Filipina presented with 1-year history of recurrent lower abdominal pain, abdominal swelling and vomiting. Ultrasound of the abdomen revealed a large cystic abdomino-pelvic mass densely adherent to the intestinal and uterine wall with moderate ascitis. ...
Slapa Rafal Z - - 2012
Although elastography can enhance the differential diagnosis of thyroid nodules, its diagnostic performance is not ideal at present. Further improvements in the technique and creation of robust diagnostic criteria are necessary. The purpose of this study was to compare the usefulness of strain elastography and a new generation of elasticity ...
Yokoyama Junkichi - - 2012
In the following report we discuss a very rare case of malignant T-cell lymphoma of the thyroid gland that developed in a 70-year-old woman with a past history of hypothyroidism due to chronic thyroiditis. The chief complaint was a rapidly growing neck mass. CT and ultrasonographic examination revealed a diffuse ...
Guerrissi Jorge O - - 2012
ABSTRACT: Ectopic thyroid tissue with no orthotopic gland is extremely rare; malign transformation of ectopic thyroid is also an uncommon event, and rarer is the follicular variant of papillary carcinoma. In this clinical report, a case with submandibular ectopic thyroid without orthotropic thyroid gland is presented. Treatment was a complete ...
Khan S A - - 2012
Solitary thyroid nodule (STN) is a common thyroid disorder. Clinically recognized thyroid carcinoma constitutes less than 1% of human malignant tumours. The risk of malignancy in solitary thyroid nodule is greater than other thyroid swelling. The risk of malignancy in generalized thyroid swelling is about 3% and in solitary thyroid ...
Song Ju Young - - 2012
Objective: To evaluate the effectiveness of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and to analyze the causes of unclear diagnoses following BSRTC adoption. Study Design: According to the BSRTC, we reclassified cytologic samples originally diagnosed as 'indeterminate' with sequential surgical resection. Then, we analyzed the causes of cases, ...
Vujhini Sudhir Kumar - - 2012
Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy is a rare disease involving the lymph nodes. Extranodal RDD involving the thyroid is extremely rare. So far, six cases of RDD involving thyroid have been reported in the literature; all have occurred in females with a mean age ...
Sengupta Arup - - 2012
Global prevalence of thyroid cancer has been on the rise in recent decades. To study the clinical presentations to reach an agreement for diagnosis and optimal management of incidentally revealed thyroid swellings for early diagnosis. A prospective study was carried out on 178 cases of incidentally detected thyroid swelling attending ...
Rossi Esther Diana - - 2012
Fine-needle aspiration biopsy is regarded as an important tool for diagnosing thyroid lesions because of its simplicity, safety, and cost-effectiveness. Its role in correctly characterizing the group of indeterminate lesions or follicular-patterned neoplasms (FN) might be more decisive. Liquid-based cytology (LBC) is a technique based on the use of a ...
Sanii Sanaz - - 2012
Purpose: Definite diagnosis of follicular thyroid carcinoma (FTC) is based on the presence of capsular or vascular invasion. To date, no reliable and practical method has been introduced to discriminate this malignant neoplasm from follicular thyroid adenoma (FTA) in fine needle aspiration biopsy material. Matrix metalloproteinase-2 (MMP-2), by degrading extracellular ...
Lyons Rebecca - - 2012
A multinodular goitre with cystic degeneration with haemorrhage and subsequent calcification is a common occurrence in long-standing multinodular goitres. But extensive enlargement and calcification causing obstructive symptoms including dysphagia and tracheal shift has not been commonly reported in the literature. Our patient, an 82-year-old man presented with long-standing dysphagia and ...
Stanojevic Boban - - 2012
Struma ovarii (SO) is a rare form of ovarian mature teratoma in which thyroid tissue is the predominant element. Because of its rarity, the differential diagnosis between benign and malignant SO has not been clearly defined. It is believed that malignant transformation of SO has similar molecular features with and ...
Popli Manju Bala - - 2012
The objective was to assess the utility of gray-scale USG to identify patterns of thyroid nodules and to correlate the characteristics of benign and malignant nodules with pathological diagnosis. From September 2009 to August 2010, a total of 203 patients (17 males and 186 females), with 240 nodules detected at ...
Mitsimponas Konstantinos T - - 2012
Oncocytic lipoadenoma is a rare salivary gland tumour composed of adipose tissue and oncocytic epithelial cells in varied proportions. This tumour is still not included in the current WHO classification of salivary gland neoplasms. We herein report a further case of oncocytic lipoadenoma originating in the parotid gland of a ...
Kushwaha Jitendra Kumar JK Surgery Department, CSM Medical University, Lucknow, Uttar Pradesh, India. - - 2012
Ectopic thyroid glands generally occur in the midline as a result of abnormal median migration. The presence of these ectopic glands, lateral to the midline is rare. Here, the authors present one case of papillary carcinoma of thyroid arising from an ectopic thyroid tissue in branchial cleft cyst presented as ...
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