Search Results
Results 301 - 350 of 795
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Rogozinski Amelia - - 2012
We made a prospective study evaluating the prevalence of thyroid nodular disease in acromegalic patients. Thyroid ultrasound and ultrasound-guided fine needle aspiration biopsy were performed when nodules were detected. Nodules were characterized by cytology and histopathology. We found high prevalence of nodular thyroid disorder, 23/34 (67%) in acromegalic patients. High ...
Rastogi Ashu - - 2012
Thyroid nodules are very common in the general population, but only 5% are malignant. We report the case of a man presenting with nodular goiter, and multiple swellings over the scalp and arm, with pathological fractures. On evaluation by fine needle aspiration, these swellings were found to be metastases from ...
Olson Matthew T - - 2012
Recent increases in the number of thyroid fine-needle aspiration (FNAs) biopsies and the popularity of on-site evaluation for adequacy (OSEA) have led many practices, including ours, to rely on cytotechnologists for performing OSEA. We retrospectively analyzed the accuracy of a cytotechnologist against that of a cytopathologist in performing OSEA and ...
Duick Daniel S - - 2012
Objective: To provide information on molecular biomarkers that can help assess cytologically indeterminate thyroid nodules.Methods: Published studies on immunohistologic, somatic mutation, gene expression classifier, microRNA, and thyrotropin receptor messenger RNA biomarkers are reviewed, and commercially available molecular test panels are described.Results: Thyroid nodules are common, and clinical guidelines delineate an ...
Alexander Erik K - - 2012
Approximately 15 to 30% of thyroid nodules evaluated by means of fine-needle aspiration are not clearly benign or malignant. Patients with cytologically indeterminate nodules are often referred for diagnostic surgery, though most of these nodules prove to be benign. A novel diagnostic test that measures the expression of 167 genes ...
Dilli Alper - - 2012
To evaluate the efficacy of apparent diffusion coefficient (ADC) calculation in differentiation between malignant and benign thyroid nodules. A prospective study was conducted in 52 patients. Diffusion-weighted echoplanar imaging was performed and b factors were taken as 0 and 400 s/mm(2). The mean ADC value for malignant thyroid nodules was ...
Rastogi Ashu - - 2012
Thyroid nodules are uncommon in childhood and recurrent thyroid nodules even rarer. Spindle epithelial tumor with thymus-like differentiation (SETTLE), a rare and distinctive low-grade neoplasm is amongst the differential diagnosis of solitary thyroid nodule in children. We describe a boy who underwent completion thyroidectomy for SETTLE in the thyroid remnant ...
Yang G C H - - 2012
G. C. H. Yang, A. M. Schreiner and W. Sun Can abundant colloid exclude oncocytic (Hürthle cell) carcinoma in thyroid fine needle aspiration? Cytohistological correlation of 127 oncocytic (Hürthle cell) lesions Objective:  The objective of the present study was to find out whether the presence or absence of certain cytological ...
Richmond Bryan K - - 2012
Published data suggest that the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) is valuable in directing therapy of thyroid nodules. Literature examining the effect of the BSRTC on management when compared with pre BSRTC is lacking, however. This study evaluates the impact of applying the BSRTC retrospectively to a series ...
Chalhoub Michel - - 2012
Sampling of solitary thyroid nodules (STNs) is a common procedure performed for cytological diagnosis. The easiest and safest method is ultrasound guided fine needle aspiration biopsy (US-FNAB). This technique is usually performed under local anaesthesia in an office setting. In contrast, sampling a substernal STN could prove to be more ...
Gutenberg Angelika - - 2012
We report a young woman with sudden and severe retroorbital headache, neck pain, and a large sellar mass extending to the suprasellar cistern. A presumptive diagnosis of non-secreting pituitary macroadenoma undergoing apoplexy was made and transphenoidal surgery performed. Histopathology revealed mononuclear infiltration and marked non-hemorrhagic necrosis of the anterior pituitary ...
Tan Bryan Y BY Department of Orthopaedic Surgery, Tan Tock Seng Hospital, - - 2012
We present a case of left suprascapular nerve palsy in a 39- year-old female secondary to compression from a large ganglion cyst. She presented with a two month history of left posterior shoulder pain which affected her work and disturbed her sleep. Clinical examination revealed a positive O'Brien's test. Supraspinatus ...
Bhatia Kunwar S S - - 2012
To evaluate real-time shear wave ultrasound elastography (SWE) for characterizing focal thyroid lesions in routine clinical practice. Seventy-four patients with 81 focal thyroid lesions undergoing conventional US with needle cytology also underwent SWE. Absolute and relative SWE stiffness measurements on colour-coded elastograms were correlated with cytology and their discriminatory performances ...
Vivanco Maritza - - 2012
BACKGROUND: The risk of radiation-induced benign and malignant thyroid nodules is well known. OBJECTIVE: The aim of this study was to determine the occurrence of thyroid nodules and carcinomas after fractionated total body irradiation (TBI) preceding hematopoietic stem cell transplantation (HSCT) for malignant hematologic disease during childhood. METHODS: We conducted ...
Fu Xianshui - - 2012
PURPOSE: To evaluate color-Doppler features predictive of focal Hashimoto's thyroiditis. MATERIALS AND METHODS: A total of 521 patients with 561 thyroid nodules that underwent surgeries or gun biopsies were included in this study. These nodules were divided into three groups: focal Hashimoto's thyroiditis (104 nodules in 101 patients), benignity other ...
Moraitis Sotirios - - 2012
A 70-year-old woman was admitted to our department for investigation and treatment of a progressively enlarging multinodular goiter and a fast growing mass infiltrating the sternum. The patient was euthyroid, but computed tomography (CT) and ultrasonography showed a mass in the anterior mediastinum infiltrating the sternum, with a dominant nodule ...
Cheng Vicky - - 2012
Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, whereas mucosa-associated lymphoid tissue (MALT) lymphoma of the thyroid gland is uncommon. Simultaneous occurrence of both disease entities is very rare. Patient findings: A 59-year-old man with known hypothyroidism from Hashimoto's thyroiditis (HT) was seen for thyroid ...
Li Yaqiong - - 2012
A form of Hashimoto's thyroiditis with lymphoplasmacytic sclerosing changes and increased numbers of IgG4-positive plasma cells has recently been reported in the literature. These histopathological features suggest that this subtype of Hashimoto's thyroiditis may be closely related to IgG4-related disease. Therefore, this unique form of IgG4-related Hashimoto's thyroiditis, which is ...
Bose Shikha - - 2012
The Bethesda system for reporting thyroid cytopathology formulated in 2007 has standardized reporting of thyroid cytology specimens and streamlined management algorithms. Although 3 of the categories (benign, malignant, and nondiagnostic) are standardized and improved, the remaining 3 (follicular lesion of undetermined significance, follicular neoplasm, and suspicious for malignancy) remain fraught ...
Chang M H - - 2012
First reported by Nager in 1927, unilateral vocal cord paralysis associated with thyroid disease suggests the malignant and irreversible nature of the thyroid lesion. This condition is rarely seen in benign thyroid diseases, and the function of the vocal cord does not usually return. We present a 54-year-old woman with ...
Gu Jiying - - 2012
Objectives- This study aimed to evaluate the diagnostic value of acoustic radiation force impulse (ARFI) elasticity imaging for differentiating between benign and malignant thyroid lesions. Methods- Hospitalized patients needing thyroid surgery were evaluated. After routine thyroid sonography, the patients underwent ARFI elasticity imaging. Virtual Touch tissue imaging (VTI) and Virtual ...
Enriquez Miriam L - - 2012
The columnar cell variant of papillary thyroid carcinoma (CCV-PTC) is a rare subtype of PTC that exhibits morphologic features often described as reminiscent of secretory endometrium or colonic adenomas/adenocarcinomas. CDX2, a nuclear transcription factor, is important for intestinal development. It is normally expressed in intestinal epithelium and is also detected ...
Nacamulli Davide - - 2012
OBJECTIVE: diagnosing thyroid nodules preoperatively using traditional diagnostic tools -ultrasonography (US) and cytology - still carries a considerable degree of uncertainty and surgery is recommended for a far from negligible number of patients simply for diagnostic purposes. Thyroid elastosonography (USE) and BRAF analysis have recently proved useful in detecting thyroid ...
Soelberg Kerstin Kathrine - - 2012
Background: The expanding use of 18F-fluoro-deoxy-glucose positron emission tomography (18F-FDG PET) has led to the identification of increasing numbers of patients with an incidentaloma in the thyroid gland. We aimed to review the proportion of incidental thyroid cancers found by 18F-FDG PET or PET/CT imaging. Methods: Studies evaluating thyroid carcinomas ...
Patel Manish N - - 2012
A 4 year-old girl was referred for CT of her neck for suspected submental lymphadenopathy and was found to have an incidental low-attenuation thyroid mass. Subsequent thyroid ultrasound showed a heterogeneous thyroid mass with punctate areas of increased echogenicity. Cytologic examination was consistent with ectopic intrathyroidal thymic nodule. We review ...
Rossi Martina - - 2012
Context:Ultrasound (US)-guided fine-needle aspiration biopsy (FNAB) is the most reliable nonsurgical test for distinguishing benign from malignant thyroid nodules. However, there is no consensus on which nodules should undergo FNAB.Aims:The aims of this study were to evaluate the utility of US-guided FNAB in the diagnostic assessment of nodules with or ...
Nagarajah James - - 2012
Background: Fine-needle aspiration biopsy (FNAB) is a simple technique for the investigation of suspicious thyroid nodules. However, low success rates are reported in the literature. The aim of this prospective study was to compare the clinical performance and impact of an automatic aspirator, referred to here as Aspirator 3, to ...
Lubitz Carrie Cunningham - - 2012
Abstract Background: Guidelines from the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference recommend repeat fine needle aspiration biopsy (FNAB) after three months for thyroid nodules with a non-diagnostic (ND) result. Our aims were to assess which factors influenced clinical management and to determine if the ...
Maldi Elena - - 2012
Extra-osseous Ewing sarcomas/peripheral primitive neuroectodermal tumors (EOES/pPNETs) are high-grade malignant tumors found in various organs, such as the lung, skin, intestine, kidney and female genital tract; however, to the best of our knowledge, only two cases have previously been identified in the thyroid gland. We describe a case of primary ...
Goldfarb Melanie - - 2012
Background: Thyroid nodules in pediatric patients may carry a greater risk for malignancy than in adults. Most nodules > 1cm in patients  21 years of age may require thyroidectomy for definitive diagnosis and treatment. Although clinic based ultrasound (CBUS) has been shown useful in the evaluation of thyroid nodules ...
Choi Nami - - 2012
To determine the prevalence of thyroid incidentalomas detected by time-resolved magnetic resonance angiography (TRMRA) and to evaluate their clinical significance by using an ultrasonographic (US) and cytologic correlation. We retrospectively reviewed 2010 consecutive TRMRA examinations performed at our institution between August 2006 and April 2010. The TRMRA findings of thyroid ...
Walsh Jonathan - - 2012
Objective. The purpose of this study is to determine if crawling wave elastography, a novel sonoelastography technique, can be used to provide quantitative measurements of thyroid tissue shear velocity (a measure of tissue stiffness) and distinguish between benign and malignant thyroid nodules.Study Design. Diagnostic test assessment.Setting. Academic university.Subjects and Methods. ...
Lim Dong-Jun - - 2012
The objective of this study was to evaluate interobserver agreement and intraobserver reproducibility in thyroid ultrasound elastography. Fifty-six patients (56 nodules) were enrolled for this prospective study between December 2010 and March 2011. All patients were scheduled for thyroid surgery because their nodules had been found by fine-needle aspiration biopsies ...
Kmieć Piotr - - 2012
Sarcoidosis rarely involves the thyroid gland. Pain in the thyroid gland area was only sporadically reported in patients suffering from this disease. The aim of this paper is to report and discuss the cases of two female patients with Graves' disease who presented painful, rapidly growing, recurrent goiters (after strumectomy ...
Juliano Amy Fan-Yee - - 2012
Infectious and autoimmune diseases account for the majority of benign conditions of the thyroid gland. They are usually diagnosed and followed by clinical examination and laboratory analyses, but when imaged, ultrasonography and computed tomography are the modalities of choice. In particular, fine needle aspiration under ultrasound guidance may be invaluable ...
Prado Héctor - - 2012
Ectopic thyroid is an uncommon condition defined as the presence of thyroid tissue at a site other than the pretracheal area. When the process of embryologic migration is disturbed, aberrant thyroid tissue may appear. In most cases, ectopic thyroid is located along the embryologic descent path of migration as either ...
Joseph J - - 2012
Investigation of the anterior midline neck lump has been debated over the years with little agreement on best practice. Thyroglossal duct cysts (TDCs) are the most common aetiology. A TDC may contain ectopic thyroid tissue, which may affect the decision to excise. A computerised survey was sent to a representative ...
Kouniavsky Guennadi - - 2012
Thyroid nodules are very common and fine needle aspiration (FNA) is a very sensitive means of diagnosis. However, its limitations include the fact that the cytology reports are often indeterminate or suspicious only. The quest for adjunctive measures to improve its specificity has been ongoing for decades, but significant results ...
Nam Meeyoung - - 2012
Objectives- The purpose of this study was to correlate the clinicoradiologic and pathologic features of thyroid lymphoma and to identify the most useful diagnostic method for thyroid lymphoma as the first line. Methods- Our study population included 16 patients with a diagnosis of thyroid lymphoma by fine-needle aspiration, core biopsy, ...
Bouhabel Sarah - - 2012
Traditional teaching demonstrated that solitary thyroid nodules were more likely to be malignant. Newer studies show that there is no clear answer regarding the influence of the number or the distribution of nodules on the risk of malignancy. The purpose of this study was to establish whether patients undergoing thyroid ...
Choi In Jae - - 2012
A 31-year-old man presented with acute onset of paraplegia. The patient's history was significant for thyroid carcinoma that had been treated 2 years earlier by thyroidectomy. A magnetic resonance imaging scan showed an enhancing intramedullary lesion at T7-8. Patient underwent surgical treatment and a tumor with hematoma was resected via ...
Langer Jill E - - 2012
Thyroid nodules are a common clinical problem and are noted much more commonly on imaging examinations than are apparent by palpation. Fine-needle aspiration biopsy (FNA), which yields a cytology specimen for analysis, is the standard test to determine whether surgical removal of a detected nodule is recommended. This article will ...
Yang G C H - - 2012
G. C. H. Yang, K. Fried and P. H. Levine Detection of medullary thyroid microcarcinoma using ultrasound-guided fine needle aspiration cytology Objective:  Compared with incidental papillary thyroid microcarcinoma (microPTC), incidental medullary thyroid microcarcinoma (microMTC) is clinically more significant. The objective of the present study was to summarize our experience in ...
VanderLaan Paul A - - 2012
Most malignancies identified by thyroid fine-needle aspiration (FNA) are papillary thyroid carcinoma (PTC). This study sought to determine if clinically adverse features of PTC correlate with the preceding cytologic diagnosis. Thyroid FNA diagnoses were correlated with subsequent histopathologic findings. From 6175 thyroid FNAs, histologic follow-up confirmed PTC in 52 of ...
Sung Jin Yong - - 2012
OBJECTIVES: To retrospectively compare the accuracy of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for the diagnosis of thyroid malignancy METHODS: We evaluated the results of FNA and CNB in 555 consecutive thyroid nodules with final diagnoses (malignancy 318, benign 237). All patients underwent FNA and CNB simultaneously for each ...
Cheng Vicky - - 2012
Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer whereas mucosa-associated lymphoid tissue (MALT) lymphoma of the thyroid gland is uncommon. Simultaneous occurrence of both disease entities is very rare. Patient findings: A 59-year-old male with known hypothyroidism from Hashimoto's thyroiditis (HT) was seen for thyroid ...
Hadfield Catherine A - - 2012
Over a 5-mo period, three diplodactylid geckos housed at the National Aquarium were diagnosed with proliferative thyroid lesions: a rough knob-tail gecko (Nephrurus amyae), a smooth knob-tail gecko (Nephrurus levis), and a marbled velvet gecko (Oedura marmorata). Clinical signs included an intraoral mass or ventral throat swelling (or both), oral ...
Dübüş Türkan - - 2012
Metastatic diseases of thyroid are rarely seen. For the patients who had previous malignancy in their history, metastatic lesions should not be ignored in the differential diagnosis of massive lesions in the thyroid gland, even the primary tumor was treated years ago. In this article, we present a case with ...
Htwe T T - - 2012
Endemic goitre is a major concern in many parts of the world, including Southeast Asia. Goitrous thyroid lesion is postulated as a precursor lesion to thyroid cancer (TC). This paper reviews the prevalence rates and characteristics of TC among cases of goitrous thyroid-swelling in different parts of Malaysia and Myanmar. ...
Kanzaki Ryu - - 2012
Intrathoracic goiters account for 3.1%-5.8% of all mediastinal masses. Primary intrathoracic goiters, which receive their blood supply from mediastinal vessels and disconnect at the cervical thyroid, are even rarer. This report presents two cases of surgical resection of benign and malignant primary intrathoracic goiters. Usefulness of a whole-body (18)F-fluorine-2-fluoro-D: -glucose ...
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