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Results 701 - 750 of 795
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O'Malley F P - - 1990
There are a number of benign, small-acinar lesions in the prostate gland that may be difficult to differentiate from small-acinar adenocarcinoma. An important diagnostic criterion in this differentiation is the loss of the basal layer in small-acinar adenocarcinoma and its preservation in benign conditions. A monoclonal antibody to high-molecular-weight cytokeratins ...
Maksem J A - - 1990
The preparation and use of an alternate collection device for aspiration biopsy of the prostate is presented. The device is inexpensive and can be constructed from readily available office materials. Its use in conjunction with a liquid-phase collection of cellular products of aspiration biopsy by a backwash technique is described. ...
Gold M H - - 1989
We describe a father and two daughters with hereditary benign telangiectasia. Both girls had numerous telangiectases distributed over the upper limbs, trunk, face, and vermilion border of the lips. The father displayed less extensive lesions and had been unaware of their presence. All three patients were in good health; the ...
Som P M - - 1989
Most sinonasal lesions that extend into the anterior cranial fossa are malignant tumors. However, benign inflammatory polypoid disease can also rarely be manifested in this manner. Fourteen surgically proved cases of such benign and malignant disease were studied with magnetic resonance (MR) imaging. The appearances of the benign and the ...
Kransdorf M J - - 1989
This study reports 42 cases of histologically proven and radiographically correlated primary patellar tumors. Despite diverse histologic diagnoses, the radiographic appearances of benign as opposed to malignant patellar neoplasms are essentially indistinguishable. Although the literature suggests that giant cell tumor is the most frequent benign tumor of the patella, the ...
Rubenstein M - - 1989
The development of antisera with reactivities against intermediate filaments, differentiation antigens, and secretory products has aided in identification and characterization of tissue specimens. Such evaluations may assist pathologists in distinguishing between benign (BPH) and malignant (CAP) tissue of prostatic origin. However, attempts to employ this technique are thwarted by 1) ...
Bostwick D G - - 1988
Two putative premalignant lesions of the prostate have been identified. Prostatic intraepithelial neoplasia (PIN) is characterized by proliferation and anaplasia of cells lining ducts and acini. Atypical adenomatous hyperplasia (AAH) consists of a localized proliferation of small round glands without cytologic atypia. PIN and AAH may be confused with well-differentiated ...
Gracey D R DR Division of Thoracic Diseases and Internal Medicine, Mayo Clinic, Rochester, MN - - 1988
Of three patients with lung-biopsy-proven benign lymphocytic angiitis and granulomatosis, two experienced complete resolution of their disease from therapy with chlorambucil and one underwent spontaneous remission with no drug therapy after lung biopsy and removal of a benign spindle cell thymoma. Clinically, it is difficult to determine whether benign lymphocytic ...
Ostrzega N - - 1988
The efficacy of utilizing immunocytochemical staining of prostatic basal cells in separating benign from malignant prostatic epithelium was tested by staining fine-needle aspiration smears of prostatic lesions with the monoclonal antibody EAB-903. This antibody has been shown to stain keratin subtypes present in the prostate only in basal cells. The ...
Rhyne T R - - 1988
Benign migratory stomatitis is a relatively rare entity, but because of its benign nature and clinical characteristics, it should be easily recognized by the general practitioner. Biopsy is usually not indicated and treatment consists of reassuring the patient that the lesions are benign even though they may disappear, reappear, and ...
Ayala F - - 1988
A case of benign cephalic histiocytosis in a 18-month-old male child is reported. Characteristic distribution of the maculo-papular lesions on the cheeks, forehead and earlobes, in addition to light and electron microscopical findings permitted the diagnosis of this rare disorder. Ultrastructurally, worm-like and comma-shaped bodies were seen in the cytoplasm ...
Koga A - - 1988
In 411 patients undergoing cholecystectomy, benign polyps were present in 32 gallbladders and malignant polyps were present in eight. Histologically, cholesterol polyps accounted for most of the benign lesions, and all the malignant lesions were adenocarcinomas. Gallstones coexisted in 50% of the malignant lesions and endoscopic retrograde cholangiography revealed anomalous ...
Terrill R Q - - 1987
Two cases of benign chondroid syringoma of the hand are described. Both patients did not have this tumor in the differential diagnosis at the time of operation. The importance of this tumor lies in its recognition. Eighty-two percent of the malignant chondroid syringomas occur in the extremities, and the differences ...
Khansur T - - 1987
The clinical records of all patients with granular cell tumor seen at our institution over a 20-year period were reviewed. Three patients with malignant, and 37 with benign tumor, were identified. Eleven patients had multiple benign lesions. Three had a history of familial occurrence. Clinical and pathologic features and the ...
Schmidt S S - - 1987
We describe a patient undergoing exploration for an epididymectomy in whom a unique apparently multicystic lesion of the testis resulted in orchiectomy. On microscopic examination the lesion was proved to be a benign, previously unreported condition wherein the tunica albuginea was split by an invasion of testicular tubules. We postulate ...
Deutch S J - - 1987
A review of 2,100 consecutive computed tomographic (CT) examinations yielded 160 cases of abdominal lymphadenopathy, of which nine (6%) were secondary to benign diseases. Contrary to previous reports, size, location, contour, density, relationship to the aorta, and presence of mass effect were not helpful in distinguishing benign from malignant lymphadenopathy. ...
Shenaq S M - - 1987
Tumors of the hand are relatively rare when compared to other body regions; the majority are benign in nature. Skin and soft-tissue benign tumors can be classified according to their tissue or origin. Proper diagnosis and differentiation of benign from premalignant or malignant lesions are the most important steps in ...
Zarem H A - - 1987
Benign tumors of the epidermal appendages frequently frustrate patient and doctor because of the uncertainty of the nature of the lesion and the choice that the benign lesion presents. Recognition and definitive management is usually straightforward with appropriate attention to the history and to the lesion. Knowledge of these benign ...
Lange T A - - 1987
Fifty patients who had a palpable soft-tissue mass and an apparently normal radiograph were studied with ultrasound imaging before excision or biopsy of the lesion was done. As shown by the sonograms, thirty-five lesions had a discrete echo pattern (usually reduced echoes and a clearly defined lesional margin) and fifteen ...
Corkill M - - 1987
A case of inverted papilloma of the ureter in a 62-year-old man is presented along with a literature review of 14 cases. This rare benign tumor should enter the differential diagnosis of a ureteral filling defect especially when it has a smooth configuration. Preoperative consideration of this diagnosis may lead ...
Fernandez-Britto J E JE Higher Institute of Medical Science, Habana, - - 1987
To study the atherosclerotic lesion (a.l.) in the two aorta segments (thoracic and abdominal) in a given set of autopsies (total 2043) performed during five years (1981-85) in one of the principal general hospitals in the city of Havana, a set of five variables was used as part of a ...
Haas G P - - 1986
Of 2,800 testicular procedures performed at our institution between 1965 and 1985, 233 inguinal explorations were done for suspicion of cancer. Malignancy was present in 161 patients but in 72 cases (31 per cent) benign lesions were found. Despite the benign nature of the lesion 51 of these patients (70 ...
Keller S M - - 1986
Benign symmetrical lipomatosis is an unusual disorder of fat metabolism that results in a characteristic accumulation of adipose tissue around the head and neck. Surgical extirpation is the only known effective therapy. Physical examination does not provide a comprehensive delineation of tumor extent. We present the first reported use of ...
Siegelman S S - - 1986
Computed tomography (CT) was used to examine 634 solitary pulmonary nodules (SPNs). Each lesion was assessed as benign or indeterminate on the basis of CT criteria. Benign nodules made up 44% of all SPNs and 58% of the 431 that were 2 cm or less in diameter. All malignant SPNs ...
Ohtsuka H - - 1986
Horizontal excision and closure is not usually recommended for lesions of the eyelids. We have used the technique for 35 benign lesions in 33 patients over the last 3 years with satisfactory results. This method is a simple one that can provide excellent cosmetic results in properly selected patients. Six ...
Eyre R C - - 1986
We report a case of a unique granulomatous lesion of the prostate and recurrent bladder neck obstruction. The lesion was histologically identical to a rheumatoid nodule and it has only been seen in patients who have undergone prior prostatic surgery. There appears to be no clinical correlation with connective tissue ...
Jurgeleit H C - - 1986
A case of a huge, self-contained cyst of pseudomyxoma peritonei arising from the rupture of a benign cystadenoma of the appendix is reported. Curative surgical removal involved both small bowel and right colon resection. The pathologic spectrum of the appendiceal mucoceles, from mucosal hyperplasia to benign cystadenoma and malignant cystadenocarcinoma, ...
Burks D D - - 1986
Using linear-array transrectal prostate sonography, malignant lesions in 43 patients and benign lesions in 74 patients were evaluated. Prostate sonography was sensitive to textural changes produced by both benign and malignant diseases. However, there was considerable overlap in the sonographic appearances of benign and malignant lesions, and there were no ...
Matthews J I - - 1986
A malignancy must be considered whenever a mass lesion is encountered on a chest roentgenogram. Unless an unequivocal diagnosis of a benign lesion is made, thoracotomy is usually indicated. Rounded atelectasis, while only having been recently described, is being encountered with increasing frequency. As illustrated by our three cases, radiologic ...
Ritchie M - - 1986
We present a 68-year-old patient who, over a two-year period, was observed to have persistent benign pneumoperitoneum. The free air was present in the abdominal cavity without gastrointestinal perforation or pneumatosis cystoides intestinalis. The persistent pneumoperitoneum was a benign process and was not associated with peritonitis or other ill effects. ...
Higginbotham L H - - 1986
Erosive adenomatosis of the nipple is a benign lesion that clinically mimics Paget's disease of the nipple but has the histologic features of syringocystadenoma papilliferum. Some cases have been mistaken for intraductal papilloma or well-differentiated adenocarcinoma, and unnecessary mastectomies have been performed. Recognition of this lesion is important because it ...
Tytgat G N - - 1986
Some reflections and critical comments are given with respect to the application of Nd:YAG laser photocoagulation in benign conditions such as benign (anastomotic) strictures and especially benign polypoid adenomatous lesions of the gastrointestinal tract. Many questions still need to be answered before the full impact of laser in benign lesions ...
Upton J D - - 1986
We analyzed the surgical and pathological records of 90 patients who underwent surgical exploration of solid scrotal masses during a 5-year period. Sixteen patients had benign lesions, including 10 adenomatoid tumors, 3 fibrous pseudotumors, 2 fibromas and 1 dermoid cyst. Twelve patients with benign lesions were treated by local excision ...
Shatz A - - 1986
A rare case of benign osteoblastoma of the mandible, with clinical, radiologic, and histologic findings, is reported. The difference between benign osteoblastoma and osteoid osteoma is discussed, since these lesions share similar features that are seen in the case presented. It is suggested that both lesions should be diagnosed as ...
Manivel C - - 1986
Two new cases of pilomatrix carcinoma are reported. They were studied immunohistochemically for the presence of high and low-molecular weight cytokeratins, beta-2-microglobulin, S-100 protein, carcinoembryonic antigen, epithelial membrane antigen, blood group isoantigens, and peanut agglutinin binding. Results of these studies were compared with those obtained in immunohistologic analysis of 13 ...
Rifkin M D - - 1986
Transrectal endosonography is one of the most sensitive techniques to evaluate prostatic disease and is far more accurate than conventional sonography. A retrospective review of sonographic characteristics of the prostate was made in an attempt to define the ability of the technique to distinguish benign from malignant disease. Analysis included ...
Ferguson C M - - 1985
Three cases of benign duodenocolic fistula are presented, and the diagnosis and treatment reviewed. Patients with benign duodenocolic fistulas usually complain of diarrhea, and occasionally nausea and feculent vomiting. Physical examinations are nonspecific, revealing wasting from the chronic diarrhea. Barium enemas are usually diagnostic. Therapy consists of excision of the ...
Ree H J - - 1985
Ricinus communis agglutinin (RCA) staining of malignant histiocytosis (two cases) and tissue infiltrates of monoblastic leukemia revealed two distinct macrophage-histiocyte types: one with cytoplasmic staining (RCA+), the other without (RCA-). RCA+ cells corresponded to benign-appearing histiocytes without nuclear atypia, whereas RCA-cells were cytologically malignant. In one case of malignant histiocytosis, ...
Kruger M - - 1985
In a patient presenting bilateral sensory neuropathy, sequential involvement of the two sides of the face with spontaneous recovery on the initially altered side is a peculiar feature which emphasizes the benign character of this unusual condition. Provided that repeated clinical evaluation discloses no underlying pathological process, sensory trigeminal neuropathy ...
Brownstein M H - - 1985
An important, yet neglected, problem in dermatopathology, is the evaluation of the benign acanthomas, the benign tumors of epidermal keratinocytes. The benign acanthomas may be simulated by lesions which are not benign (e.g. actinic keratosis), not tumors (e.g. normal plantar skin), or are not epidermal (e.g. dermatofibroma). In addition to ...
Griffiths H - - 1985
Solitary rib lesions are not uncommon. They are frequently asymptomatic and usually benign. Virtually all of the malignant tumors are associated with an obvious soft tissue mass which merits further investigation. However, should any of the benign appearing lesions either become symptomatic, change appearance or start growing then they too ...
Garty I - - 1985
A patient with a benign calcified pulmonary focus concentrating 99mTc-methylenediphosphonate is described. To the best of our knowledge, this is the first description of the accumulation of 99mTc-phosphate compounds in a benign calcified focus of the lung. The value of a routine correlation with X-ray study in every case of ...
Wolf B A - - 1985
Considerable confusion exists regarding the nature of benign dermal cylindroma of the external auditory canal. In the past, authors have used the term cylindroma to refer to malignant lesions such as adenoid cystic carcinoma. Benign dermal cylindroma is a specific clinical entity consisting of benign tumors arising from the epidermal ...
Fan K - - 1984
A papillary adenomatous polyp of the verumontanum was studied morphologically and immunochemically. This rare polypoid neoplasm displayed rather typical prostatic acinar epithelium, and by immunoperoxidase method differentiation products of prostatic origin could be demonstrated easily. Findings support the concept that this type of lesion is prostatic in origin and probably ...
Berger T G - - 1984
A histopathologic study of 108 lesions of lichenoid benign keratosis from 104 patients confirmed previously observed clinicopathologic features such as involvement of whites, age range of 35 to 65 years, female predominance, single keratosis, common location on the arm or presternal area, and failure of clinical recognition of the lesion. ...
Schipper H I - - 1984
Paraproteins display a characteristic pattern of limited heterogeneity on isoelectric focusing. In a group of 50 patients with various neurological disorders and paraproteinaemia this pattern could be demonstrated in serum and cerebrospinal fluid simultaneously, regardless of the form of nervous system involvement or of the function of the blood-cerebrospinal fluid ...
Newland J R - - 1984
The tongue is the site of origin of a variety of reactive, neoplastic, and developmental swellings that all share a benign pattern of growth. They are significant because they can interfere with function, they can be mistaken for malignancy, or they can represent part of a syndrome. Distinctive clinicopathologic features ...
Ali M H - - 1984
Nine benign retention (juvenile) large bowel polyps with an unusual histologic appearance, developed in a 23-year-old man at the site of anastomosis 7 years after ureterosigmoidostomy. Benign tumor occurring as a complication of this operation are very uncommon, and no previously reported case has had more than two lesions. The ...
Goldman R L - - 1984
We describe two cases of benign neural invasion by proliferated islet cells in a background of chronic pancreatitis, and cite additional examples of benign neural invasion in other locations. This phenomenon, which represents the presence of collections of benign epithelial structures in a nerve or in a perineural space, is ...
Mambo N C - - 1984
A clinicopathologic study of 18 eccrine acrospiromas with atypical nuclear changes is presented. The changes included nuclear pleomorphism, prominent nucleoli, chromatin condensation, multinucleate giant cells and increased mitotic activity. Of the 5 neoplasms that occurred, 2 recurred once and were histologically and clinically benign, and the other 2 recurrences were ...
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