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Ağaçkiran Yetkin Y Department of Pathology, Atatürk Chest Diseases and Thoracic Surgery Education and Research Hospital, ANKARA, - - 2014
Benign metastasizing leiomyoma is typically seen in young premenopausal women after a mean period of 15 years following uterine leiomyoma or hysterectomy surgery. They are usually incidentally seen on chest x-rays and are nodular lesions that appear as bilateral nodules with a benign appearance and consist of smooth muscle proliferation. ...
Cormio Luigi - - 2014
Bladder metastases from lung adenocarcinoma are extremely rare; in the seven previously reported cases, the finding of an intact epithelium overlying the bladder tumour was considered suggestive of a secondary lesion. We describe the first case of bladder metastasis from lung adenocarcinoma whereby endoscopic appearance was strongly consistent with primary ...
Zhou Jianqiao J Department of Ultrasound, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200025, - - 2014
To evaluate the stiffness of the surrounding tissue of breast lesions using the strain ratio assessment method by ultrasound (US) elastography. This was an institutional ethics committee approved prospective study. A total of 127 breast lesions in 118 women (mean age 48.23 ± 14.32, range 20-90) were examined with conventional and elastographic ...
Zheng Minjuan M Ultrasound Department, Xijing Hospital, Fourth Military Medical University, Xi'an, China, - - 2014
To evaluate the feasibility and accuracy of high-frequency sonography (US) in diagnosing traumatic brachial plexus (BP) lesions and neoplasms in the adult. Eleven patients with suspected BP closed trauma, 6 patients with BP neoplasm, and 12 healthy volunteers were scanned. The US findings were compared with surgical findings. The interscalene ...
Su Lowell L 1Surgical Resident, Department of General Surgery, Marshfield Clinic, Marshfield, Wisconsin, - - 2014
Solitary metastatic pancreatic lesions comprise 0.5 - 3% of all pancreas neoplasms, most commonly arising from primary tumors of the kidney, lung, or colon. Synchronous metastatic pancreatic lesions are exceptionally rare. Only 25 cases of isolated colorectal pancreatic metastasis amenable to resection have been reported, 11 of those in the ...
Thomas Eric J EJ Resident, Division of Foot and Ankle, Department of Orthopedic Surgery and Rehabilitation, University of Florida Health at Jacksonville, Jacksonville, FL. Electronic address: - - 2014
Carcinoma cuniculatum is a rarely occurring, low-grade variant of squamous cell carcinoma most commonly found in the forefoot. It should be suspected in the differential diagnosis for chronic nonhealing verrucous wounds. The initial diagnosis of carcinoma cuniculatum is difficult and often delayed and can require repeated histopathologic evaluation by an ...
Marković Vinko V From the *Department of Nuclear Medicine, and †Clinical Institute of Radiology, University Hospital Split, University of Split Medical Faculty, Split, - - 2014
Dual ectopic lingual and sublingual thyroid gland is an extraordinarily rare condition. We present 1 patient with subclinical hypothyroidism. The clinical examination revealed that the thyroid gland was not palpable in its usual cervical location, whereas ultrasonography confirmed an empty thyroid bed without any ectopic thyroid tissue in the rest ...
Geisinger Kim R KR Piedmont Pathology Associates, Hickory, NC, USA, - - 2014
A 50-year-old woman underwent a fine-needle aspiration biopsy for progressive enlargement of the left thyroid lobe which was cystic and solid on ultrasound exam. The smears contained innumerable eosinophilic leukocytes along with lymphocytes, Hurthle cells, cells from a papillary thyroid carcinoma (PTC), and atypical glandular and squamous cells. The cytologic ...
Ryan S S Departments of Otolaryngology, Royal Victoria Eye and Ear Hospital, Dublin 2, Ireland, - - 2014
Treatment for primary hyperparathyroidism necessitates complete excision of involved parathyroid tissue. Simultaneous thyroidectomy may also be required in order to optimise operative access and/or where suspicion of synchronous abnormal thyroid pathology exists. We sought to determine how often simultaneous removal of thyroid tissue was required during parathyroidectomy and the nature ...
Lee Chung Hun CH Department of Pathology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, South - - 2014
Preoperative cytologic diagnosis of solitary extramedullary plasmacytoma (SEP) presents a challenge to cytopathologists because this tumor rarely occurs as a primary thyroid malignant neoplasm. In this report, we provide the first description of liquid-based cytomorphologic findings of SEP observed on fine-needle aspiration biopsy (FNAB) of the thyroid. A 56-year-old woman ...
van Hagen P P Department of Surgery, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The - - 2014
Human epidermal growth factor receptor 2 (HER2) is overexpressed in a subset of esophageal adenocarcinomas. Frequently, biopsy material is used for evaluation of HER2 status. The aim of the study was to determine if HER2 expression in preoperative endoscopic biopsies is representative for the entire tumor. Preoperative endoscopic biopsies and ...
Ashraf Mohammad Javad MJ Department of Pathology, Shiraz Medical School, Shiraz, - - 2014
Oncocytic lipoadenoma is a rare benign neoplastic lesion of salivary gland. To the best of our knowledge, the detailed cytomorphological findings were described only in two cases. We are reporting a 56-year-old woman who presented with 1-year history of right parotid gland mass. Cytologic examination revealed tight clusters of bland ...
Asgari Seyed Alaeddin SA Urology Research Center, School of Medical, Guilan University of Medical Sciences, Razi Hospital, Rasht, - - 2014
Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT lymphomas) are mostly seen in the gastrointestinal tract. MALT lymphomas involving kidney are extremely rare. We report on a case of MALT lymphomas of the kidney. A 74-year-old woman presented with an episode of gross hematuria and right flank pain. In ...
Faizan Mahwish M Department of Paediatric Haematology and Oncology, The Children's Hospital and ICH, - - 2014
Ewing's sarcoma, a primitive neuroectodermal tumour is a rare entity belonging to a family of neoplasms of neuroectodermal origin. These highly aggressive neoplasms primarily affect older children and young adults. They primarily involve the bones or soft tissues. A quarter of Ewing's sarcomas occur principally in the soft tissues with ...
Meng Zhaowei Z From the Departments of *Nuclear Medicine, Tianjin Medical University General Hospital; †Department of Surgery, Tianjin Stomatological Hospital; and ‡Department of Pediatrics, Tianjin Medical University General Hospital, Tianjin, People's Republic of - - 2014
A 1-year-old Chinese boy presented with a mass at the base of his tongue with dysphagia. The distal end of the lesion could be put out of his mouth, making a "double tongue" appearance. Before surgery, serum test showed euthyroidism. Thyroid scintigraphy showed good function of the orthotopic thyroid, yet ...
Walavalkar Vighnesh V Division of Cytopathology, Department of Pathology, University of Massachusetts Medical School, Worcester, Mass., - - 2014
Background: Metastases to the thyroid gland, although rare, are important entities to consider when evaluating malignant cells on a thyroid fine-needle aspiration (TFNA) specimen. Cellular TFNA specimens with small round blue cells should prompt a broad differential: florid lymphocytic thyroiditis, lymphoma, metastases, as well as primary thyroid malignancies with similar ...
Betts Guy G Department of Histopathology, The Christie NHS Foundation Trust, 550 Wilmslow Road, M20 4BX, Manchester, United - - 2014
Transcription factors have proved highly specific immunohistochemical markers e.g. TTF-1 (thyroid/lung) and CDX-2 (Gastro-intestinal). GATA3 is a transcription factor which is functionally involved with the development of breast, urothelial, epidermal, T lymphocyte and parathyroid tissue. Recent studies of GATA3 immunoprofile, including that by Miettinen et al. across 2040 epithelial malignancies and ...
Watanabe Yoshiyuki Y Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, - - 2014
Only bipolar clamps create reliable transmural lesions on the beating heart. This study evaluated the performance of a new radiofrequency (RF) device on the beating heart in an acute porcine model. Six domestic pigs were ablated with a novel bipolar RF linear device on the beating heart (ablation time of ...
Yun Ju Sik JS Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, - - 2014
Mixed squamous cell and glandular papilloma of the lung is an extremely rare benign epithelial tumor showing a mixture of squamous and glandular epithelium. Here, we report a case of mixed squamous cell and glandular papilloma that presented as a solitary nodule in the left lower lobe of a 64-year-old ...
Pieczarka Emily M EM Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, - - 2014
An 11-year-old male castrated mixed-breed dog was presented for exercise intolerance, tetraparesis, and persistent hypoglycemia. Abdominal ultrasound examination revealed 2 nodules within the right limb of the pancreas. Cytology from one nodule was consistent with a carcinoma of neuroendocrine origin, with a primary differential diagnosis of insulinoma. Histologic evaluation and ...
Park Jae Young JY Jae Young Park, Medical course, Jeju National University School of Medicine, Jeju 690-767, South - - 2014
Intestinal duplications are rare congenital anomalies that can occur anywhere in the gastrointestinal tract. They are most commonly located in the ileum and are usually detected in infancy or early childhood. Duplicated segments are usually firmly attached to and sometimes communicate with the normal gastrointestinal tract. Rarely, intestinal duplications are ...
Dalley Andrew J AJ UQ Centre for Clinical Research, The University of Queensland, Herston, Qld, 4029, Australia; School of Dentistry, The University of Queensland, Brisbane, Qld, 4000, - - 2014
Early diagnosis is vital for effective treatment of oral squamous cell carcinoma (OSCC). The optimal time for clinical intervention is prior to malignancy when patients present with oral potentially malignant lesions such as leukoplakia or erythroplakia. Transformation rates for oral dysplasia vary greatly and more rigorous methods are needed to ...
Li Gerald G Integrative Oncology Department, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada. Electronic address: - - 2014
Formalin-fixed tissue has been a mainstay of clinical pathology laboratories, but formalin alters many biomolecules, including nucleic acids and proteins. Meanwhile, frozen tissues contain better-preserved biomolecules, but tissue morphology is affected, limiting their diagnostic utility. Molecular fixatives promise to bridge this gap by simultaneously preserving morphology and biomolecules, enabling clinical ...
Tsukamoto Ayato A Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, - - 2014
Mucosa-associated lymphoid tissue (MALT) lymphoma usually arises from chronic inflammation. We herein report a case of small intestinal MALT lymphoma with protein-losing enteropathy (PLE). A 73-year-old woman presented with lower leg edema and severe hypoalbuminemia. She had a medical history of pylorus-preserving pancreaticoduodenectomy with Billroth II reconstruction. Oral and anal ...
Zander David A DA From the Department of Radiology, University of Iowa Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA - - 2014
When a child or young adult presents with a mass in the anterior portion of the neck, diagnostic considerations include a thyroglossal duct cyst and ectopic thyroid tissue. These entities are often suspected clinically, and imaging provides an opportunity to evaluate the extent, confirm the diagnosis, and evaluate for complications. ...
Kumar K V S Hari KV Department of Endocrinology, Medwin Hospitals, Nampally, Hyderabad, A.P., - - 2014
Von Hippel-Lindau (VHL) disease, which is an autosomal dominant inherited disease, is characterized by highly vascularized tumors in different organs. We report a 42-year-old male who presented to our hospital with diarrhea and weight loss of six months' duration. Ultrasonography of the abdomen revealed bilateral polycystic kidneys with multiple cystic ...
Gebauer Florian F Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany. - - 2014
Glomangiomas are rare soft tissue tumors originating from the perivascular tissue. The most common localization is in the dermis of the extremities, with a few reports of respiratory tract involvement. We present the case of a 48-year-old Caucasian female patient with a glomangioma in her left lung. It was diagnosed ...
Delitala Alessandro P AP Department of Biomedical Science, University of Sassari, Sassari, Viale San Pietro 8, 07100 Sassari, Italy. - - 2014
Thyroid metastases are clinically rare, and usually occur in patients with a history of prior malignancy and when there are metastases elsewhere. Metastases of pancreatic carcinoma to the thyroid are extremely rare, with only three cases reported in the literature. We report a patient who had a pancreatic carcinoma with ...
Roh Young Hoon YH Gastrointestinal Cancer Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Korea. ; Department of Internal Medicine, Dongnam Institute of Radiological & Medical Sciences, Busan, - - 2014
Extramedullary plasmacytoma involves organs outside the bone marrow; however, involvement of the pancreas is rare. We recently experienced a case of extramedullary plasmacytoma of the pancreas that was diagnosed by endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA). EUS-FNA, which has a high diagnostic accuracy and an excellent safety profile, is the ...
Gummalla Krishna Mohan KM Department of Diagnostic and Interventional Radiology, Tan Tock Seng Hospital, Jalan Tan Tock, Singapore. - - 2014
Morel-Lavallee syndrome (MLS) is a significant post-traumatic soft tissue injury in which the subcutaneous tissue is torn away from the underlying fascia (closed degloving), creating a cavity filled with hematoma and liquefied fat. It commonly occurs over the greater trochanter, but may also occur in the flank, buttocks and lumbodorsal ...
Chen En-Dong ED Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, People's Republic of - - 2014
Langerhans cell histiocytosis (LCH) is a rare disease, especially when it involves the thyroid gland. Awareness of ultrasonic features will be helpful for a clinician who should consider this disease in the differential diagnosis from other more common thyroid disorders, especially prior to surgery. Here, we report two patients who ...
Pramanick Angsumita A Department of Obstetrics and Gynecology, KK Women's and Children's Hospital, - - 2014
Placental site nodule (PSN) is a rare benign lesion of the intermediate trophoblast which is thought to represent incomplete involution of the placental implantation site. PSN usually presents as menorrhagia, intermenstrual bleeding or an abnormal Pap smear. PSN is benign, but it is important to distinguish it from the other ...
Lynch Michael C - - 2014
A teenage girl presented with multiple warty skin lesions and had a diagnosis of epidermodysplasia verruciformis made several years later. Later in life she presented with an extensive SCC in situ in her gluteal crease that was surgically resected with wide margins. Despite this treatment, the lesion recurred with extension ...
Nangia Rajat R Department of Oral and Maxillofacial Pathology, Himachal Institute of Dental Sciences, Rampur Ghat Road, Paonta Sahib, District Sirmour, Himachal Pradesh 173025, - - 2014
Epithelioid hemangioma is a rare benign vascular lesion that presents as a nodular lesion in the skin of head and neck region. It is a superficial vascular entity which can either be due to tumor or reactive lesion, but the exact etiology is still unknown. We hereby present a rare ...
Chan Wing P WP Wing P Chan, Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei 116, - - 2013
Diagnosis of extremity soft-tissue tumors can be challenging. Characteristics of tumor margins can help precisely identify locally aggressive or non-aggressive behavior for surgical planning, but cannot differentiate benign from malignant lesions. Most malignant tumors can have inhomogeneous signals on T2-weighted images. Although a uniform signal on T2-weighted images can be ...
Chiu Alexander S AS Department of Surgery, Biological Sciences Division, The University of Chicago, 5841 S Maryland Ave MC 5029, Chicago, IL, 60637, - - 2013
Pancreas-associated enteric duplication cysts are rare developmental anomalies that communicate with the main pancreatic duct and may be associated with recurrent acute and chronic abdominal pain in children. In adults, these lesions may masquerade as pancreatic pseudocysts or pancreatic cystic neoplasms. An adult patient with a pancreas-associated enteric duplication is ...
Ko Ji-Seung - - 2013
Primary lymphomas of the canine female genital tract are uncommon tumours. A 9-year-old intact female Lhasa Apso dog presenting with a closed pyometra underwent an ovariohysterectomy (OHE), and the hyperplastic uterine horn along with multiple follicular cysts on the right ovary was examined by histological analysis. Severe infiltration of medium-sized ...
Zhu Li - - 2013
S100P is a member of the S100 family. Increased levels of S100P have been documented in various malignancies. Binding of extracellular S100P to receptor for advanced glycation end products (RAGE) or coupling of intracellular S100P with a cytoskeletal protein, ezrin, play a crucial role in tumor growth, invasion and metastasis. ...
Takimoto N N Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, - - 2013
A subcutaneous tumour was identified in the malar region of a 14-year-old neutered female mixed breed dog. The dog was humanely destroyed and necropsy examination was performed. The tumour did not invade neighbouring tissues and no metastasis was found. Microscopically, the tumour showed a range of features including the presence ...
Thunnissen Erik - - 2013
Context.-Surgical removal and pathologic handling of lung tissue has a compressive effect upon its architecture. The effect of surgical atelectasis on morphology has not been examined in depth, especially with respect to lung adenocarcinomas. Objective.-To examine the influence of surgical atelectasis on morphologic lepidic growth pattern, mimicking papillary adenocarcinoma pattern. ...
Go Jai Hyang JH Department of Pathology, Dankook University College of Medicine, Cheonan, - - 2013
The present lesion was the first reported case of a benign intracystic phyllodes tumor in the inguinal region. We report the case of a 51-year-old female patient who presented with an inguinal mass. A clinical diagnosis of malignant lymphoma was considered in this case. The resected tumor was well-circumscribed and ...
Jang Juah J Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, - - 2013
A 73-year-old, previously healthy man presented with nausea, vomiting, diarrhea, dry mouth and febrile sensation 3 hours after eating boiled wild mushrooms. After admission, he showed progressive severe respiratory distress, pancytopenia, azotemia, hypotension, hypoxemia and consolidation of the entire left lung on chest radiography. With a preliminary diagnosis of necrotizing ...
D'Silva Shaloom S Doha, - - 2013
Background: Calretinin a 29-kDa calcium binding protein is expressed widely in normal human tissue and tumours including amelobastoma. The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts. Materials & Methods: The lining epithelium in 3 cases of ...
Pattipati Sreenivasulu S Senior Lecturer, Department of Oral Medicine & Radiology, St. Joseph Dental College & Hospital, Duggirala, Eluru , Andhra Pradesh-534004, India - - 2013
Intraoral lipomas are benign mesenchymal neoplasms that originate in mature adipose cells with differential diagnosis of other soft tissue lesions. Lipoma, rarely, occurs in the oral cavity, and it corresponds to less than 4.4%, of all benign oral soft tissue tumors. Here, we are reporting a case of lipoma that ...
Thien Ady A Department of Neurosurgery, National Neuroscience Institute, - - 2013
Soft tissue chondromas are rare, benign extra-skeletal tumours of cartilaginous origin, which may rarely occur within the spinal canal. We report a patient who presented with left lumbar radiculopathy, and a peripherally-enhancing dumbbell shaped soft tissue mass involving both the intraspinal and extraspinal compartments on MRI. This was misdiagnosed as ...
Sheik Shahila S Departments of Obstetrics & Gynecology, Sultan Qaboos University Hospital, Muscat, - - 2013
Enteric duplication cysts are rare congenital anomalies of the gastrointestinal tract. These can be suspected if cystic lesions are noted in the fetal abdomen during an antenatal ultrasonogram. The differential diagnoses of fetal intra-abdominal cystic lesions include fetal omental cysts, fetal mesenteric cysts, meconium pseudocysts and fetal ovarian cysts. We ...
Verdin V V Department of general surgery, CHR Citadelle Hospital, Lidge, Belgium. - - 2013
Pancreas ectopia / Ectopic pancreas (EP) is a rare congenital disease, most typically diagnosed in asymptomatic patients by incidental detection during surgery or at autopsy. It is defined by the presence of pancreatic tissue localized in various places drifting from the foregut or mesentery. It is subject to the same ...
Abé Tatsuya - - 2013
Keratocystic odontogenic tumor (KCOT), a developmental jaw cyst previously referred to as odontogenic keratocyst (OKC), typically arises in the jawbone. In this article, however, we report a case of KCOT located within the temporalis muscle. We compared its immunohistochemical profiles with those of authentic jaw KCOT, orthokeratinized odontogenic cyst, and ...
Nagar Sapna S Department of Surgery Beaumont Health System, 3811 West 13 Mile Road, 104-RI, Royal Oak, MI 48073, USA. Electronic address: - - 2014
Fine-needle aspiration (FNA) aids in the diagnosis of thyroid nodules. The expression of previously implicated genes was examined to potentially discriminate between benign and malignant thyroid samples. Patients included for study had cytology demonstrating follicular cells of undetermined significance, atypical cells of undetermined significance, follicular neoplasm, or suspicion of malignancy ...
Simpson R Mark - - 2013
Melanoma represents a significant malignancy in humans and dogs. Different from genetically engineered models, sporadic canine melanocytic neoplasms share several characteristics with human disease that could make dogs a more relevant pre-clinical model. Canine melanomas rarely arise in sun-exposed sites. Most occur in the oral cavity, with a subset having ...
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