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Schmitt Fernando C FC 1Ipatimup and Medical Faculty of Porto University 2Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto 3Laboratoire National de Sante - - 2014
Currently, the use of molecular techniques is widely accepted on cytology as adjuvant of morphology for diagnosis and prognosis. Moreover, the study of markers of therapeutic response has been helpful in some types of neoplasms. There are many advantages in the use of cytological material to perform molecular studies: ease ...
Lakhani Sunil R SR University of Queensland, School of Medicine and UQ Centre for Clinical Research, The Royal Brisbane & Women's Hospital, - - 2014
The 4 edition of the WHO classification of Tumours of the Breast was published in 2012, as a separate volume from the gynae book. The editors and the international panel of breast pathologists have attempted to produce a consensus document that will help to standardize classification worldwide. In addition to ...
Swerdlow Steven H SH University of Pittsburgh School of Medicine, - - 2014
The field of hematopathology is ever-changing with important new discoveries of biologic and clinical importance. We continue to learn more about the clinical, morphologic, immunophenotypic and molecular/genetic features of the seemingly innumerable types of malignant lymphomas and their benign mimics. These discoveries have very pragmatic implications affecting our daily practice ...
Law Chun-Yiu CY Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, - - 2014
Beta-ketothiolase deficiency is a rare inborn errors of metabolism (IEM) affecting the catabolism of isoleucine, characterized by severe ketoacidosis in children of 6 to 24months old. A prompt diagnosis is of paramount importance as the metabolic decompensation can be effectively reverted by glucose infusion and health outcomes are improved on ...
Lior-Hoffmann Lee L Department of Biology and ‡Department of Chemistry, New York University , 100 Washington Square East, New York, New York 10003, United - - 2014
DNA lesion bypass polymerases process different lesions with varying fidelities, but the structural, dynamic, and mechanistic origins of this phenomenon remain poorly understood. Human DNA polymerase κ (Polκ), a member of the Y family of lesion bypass polymerases, is specialized to bypass bulky DNA minor groove lesions in a predominantly ...
Nagaishi Masaya M Department of Neurosurgery, Koshigaya Hospital, Dokkyo University School of Medicine, 2-1-50 Minami-Koshigaya, Koshigaya-shi, Saitama 343-8555, Japan. Electronic address: - - 2014
Malignant gliomas of the optic pathway are rare, and their genetic alterations are poorly understood. We describe a 64-year-old woman with anaplastic astrocytoma originating from the optic pathway, together with the molecular features. She presented with progressive visual field loss, and a biopsy sample was obtained from the lesion in ...
Bhalla G G Himachal Institute of Dental Sciences , Paontasahib, HP , - - 2014
Collagenase-3 (matrix metalloproteinase-13) is a metalloproteinase (MMP) that is associated with bone lesions and exhibits variable expression patterns in odontogenic cysts; it may play a role in regulating focal proliferation and maturation of jaw cyst epithelium. We studied the localization, staining intensity and distribution of collagenase-3 in 13 periapical granulomas ...
Hakim Mumin Mushtaq Ahmed MM Department of Obstetrics and Gyneacology, Yenepoya Medical College, Mangalore, Karnataka, - - 2014
A 19-year-old unmarried woman with regular menstrual cycles presented with symptoms of vague abdominal pain of 1 month duration. General condition fair. Per abdomen-a firm, non-tender mass corresponding to 26 weeks of gestation with smooth surface, upper and lateral borders well defined, lower border not palpable was observed. Ultrasonography: left ovarian tumour ...
Thway Khin K Sarcoma Unit, Department of Histopathology, The Royal Marsden NHS Foundation Trust, 203 Fulham Road, London SW3 6JJ, - - 2014
Introduction. Soft tissue tumour pathology is a highly specialised area of surgical pathology, but soft tissue neoplasms can occur at virtually all sites and are therefore encountered by a wide population of surgical pathologists. Potential sarcomas require referral to specialist centres for review by pathologists who see a large number ...
Sanaei-Zadeh Hossein - - 2014
It is occasionally difficult to distinguish between a self-inflicted bruise and true bruise. The important point of diagnosis is a good, thorough history taking and detailed examination of the affected area. Keywords: artificial bruise - assault - heparin.
Luengo Olga O Allergy Section, Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain ; Allergy Research Group, Institut de Recerca Vall d'Hebron, Barcelona, - - 2014
The knowledge on molecular allergy diagnosis is continuously evolving. It is now time for the clinician to integrate this knowledge and use it when needed to improve the accuracy of diagnosis and thus provide more precise therapeutic and avoidance measures. This review does not intend to comprehensively analyze all the ...
Wu Howard H - - 2013
To identify the subtypes of atypia of undetermined significance (AUS) that confers a different magnitude for the risk of malignancy (RM), thyroid fine-needle aspiration (FNA) cases carrying a diagnosis of "atypical follicular cells" or "follicular lesion" with surgical pathology followup were included in this study. The direct smears of the ...
Thomas Emily K - - 2013
To characterize the incidence, etiology, presenting complaint, clinical course, and outcome of cats with pneumomediastinum. Retrospective study from the period of January 1st, 2000 to December 31st, 2010. University teaching hospital. Forty-five cats with a radiographic diagnosis of pneumomediastinum. None. Medical and radiographic records were reviewed to identify cats with ...
Terada Tadashi - - 2013
The author investigated histopathology of 1,438 consecutive rectal specimens in the last 10 years of our pathology laboratory in Japan. A computer review of pathologic reports was done. Observations of pathologic slides were performed, when appropriate. The rectal specimens were composed of 1,022 benign lesions and 416 malignant lesions. The ...
Terada Tadashi - - 2013
The author reviewed 910 cases of consecutive esophageal biopsies in the last 15 year in the pathology laboratory of our hospital. There were 693 normal mucosa and benign lesions (76.2%) and 217 malignant lesions (23.8%). No significant changes were recognized in the esophagus in 50 biopsies (5.5%). In benign lesions, ...
Moslavac Sandra - - 2012
The aim of of the study was to investigate the possible changes of primary fine needle aspiration (FNA) diagnoses after subsequent check ups. We investigated 948 thyroid nodules and the main indications for repeat FNAs were inadequate/indeterminate FNA findings and growing nodules at ultrasound check up. FNA findings were subdivided ...
Singhi Aatur D AD Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, - - 2012
Pancreatic neuroendocrine tumors (PanNETs) are typically solid neoplasms but in rare instances may present as cystic lesions. This unusual presentation can make clinical diagnosis challenging. In addition, the clinical and histopathologic characteristics of cystic PanNETs are poorly defined. We identified 53 cystic PanNETs in our single-institution experience of 491 surgically ...
Tharwat Mohamed - - 2012
This study describes the transabdominal ultrasonographic findings in 54 goats with confirmed Johne's disease (JD). Compared with the control group (0.8 ± 0.4 mm thick), the test group presented with mild (2.8 ± 0.2 mm), moderate (4.2 ± 0.4 mm), and severe (6.9 ± 1.1 mm) thickening of the intestinal ...
Sandmann Gunther H - - 2012
Traumatic shoulder dislocation may be complicated by concomitant bony injury of the glenoid rim or the humeral head. In Hill-Sachs lesions, reconstruction techniques vary widely and range from open reduction to tendon transposition or humeral head derotation. These operations are extensive and have questionable outcomes. With the expertise from vertebral ...
Morvan G - - 2012
In this case series, out of 823 ultrasound-guided injections carried out over a period of one and a half years, 60% were of the lower limb (LL). In the hip (61% of LL injections), the main indications were pathologies of the gluteal tendons and bursae (80%) and pathologies of periprosthetic ...
Jain N - - 2012
Clinically equivocal abdominal wall lesions often pose diagnostic dilemmas for clinicians. It can be equally challenging to appreciate the nature of abdominal wall lesions found incidentally on abdominal ultrasound examinations. Ultrasound is a non-ionizing, cheap, and easily accessible investigation for such lesions. It is widely used and has the added ...
Raitz R - - 2012
OBJECTIVE: To analyse the visual perceptions of different experts with respect to multilocular radiolucent lesions in circumstances when the diagnosis is either known or unknown.Methods: 6 radiographs of ameloblastomas (AMELs), keratocystic odontogenic tumours (KOTs), central giant cell lesions (CGCLs) and myxomas (MIXs) were analysed by 16 dental experts [stomatologists/oral surgeons ...
Guo Bin - - 2012
The present study aims to evaluate the effect of Galla chinensis compounds on the remineralization of two artificial root lesions morphous in vitro. Sixty bovine dentine blocks were divided into two groups and individually treated with two levels of demineralization solutions to form erosive and subsurface artificial carious lesions in ...
D'Alessandro B - - 2012
Subsurface information about skin lesions, such as the blood volume beneath the lesion, is important for the analysis of lesion severity towards early detection of skin cancer such as malignant melanoma. Depth information can be obtained from diffuse reflectance based multispectral transillumination images of the skin. An inverse volume reconstruction ...
Ryu Hyeon Min - - 2012
Accurate evaluation of side branch (SB) ostium could be critical to the treatment of bifurcation lesions. We compared measured and calculated values of side branch ostial length (SBOL) in coronary bifurcation lesions with intravascular ultrasound (IVUS). Pre-intervention and post-intervention IVUS was performed in 113 patients who underwent stent implantation of ...
Buxbaum James L - - 2012
Rapid onsite evaluation (ROSE) has been demonstrated to correlate with final cytologic interpretations and improves the diagnostic yield of endoscopic ultrasound (EUS)-fine needle aspiration (FNA); however, its availability is variable across centers. The aim of this prospective study was to evaluate whether remote telecytology can substitute for ROSE. Consecutive patients ...
Macgregor Caitlin A - - 2012
INTRODUCTION: The method used to create a melanoma trainer using simulated back skin is presented. The trainer is intended to be used to teach medical students to identify benign and malignant cutaneous pigmented lesions. METHODS: Non-Hispanic and Hispanic white melanoma trainers were created using flexible polyurethane foam and pigmented silicone ...
Brouwer Patrick A - - 2012
In achondroplastic patients with slight complaints of medullary compression the cervical spinal cord regularly exhibits an intramedullary (CHII) lesion just below the craniocervical junction with no signs of focal compression on the cord. Currently, the prevalence of the lesion in the general achondroplastic population is studied and its origin is ...
Tsai Patrick - - 2012
The aim of this study was to determine the diagnostic accuracy of 2 cone-beam computed tomography (CBCT) machines and periapical (PA) radiography in detecting simulated apical lesions created with the smallest dental burs available. By using mandibles from human cadavers, simulated apical lesions were created and then progressively enlarged in ...
Seger M - - 2012
Cardiac cryoablation applied for treating cardiac arrhythmias has shown promising results after intervention particularly for the creation of elongated lesions. A model for simulating and assessing cryoablation interventions was developed, evaluated and validated with animal experiments. We employed two simulations of different freezing outlet settings for a loop shaped cryocatheter, ...
Tharwat Mohamed - - 2012
This study evaluated the use of ultrasonography for the diagnosis of Johne's disease in camels (Camelus dromedarius). Seventy camels with confirmed Johne's disease were examined by ultrasonography and subsequent necropsy; 15 healthy camels were included as controls. The most outstanding findings were visible enlargement of the mesenteric lymph nodes in ...
Hu Yipeng Y Centre for Medical Image Computing, University College London (UCL), London, - - 2012
What's known on the subject? and What does the study add? Transrectal ultrasonography (TRUS)-guided biopsies can miss prostate cancer and misclassify risk in a diagnostic setting; the exact extent to which it does so in a repeat biopsy strategy in men with low-intermediate risk prostate cancer is unknown. A simulation ...
Wood John W JW Department of Otolaryngology, University of Miami, Miami, Florida, USA. - - 2012
Benign lesions of the nasal cavity represent a diverse group of pathologies. Furthermore, each of these disorders may present differently in any given patient as pain and discomfort, epistaxis, headaches, vision changes, or nasal obstruction. Although these nasal masses are benign, many of them have a significant capacity for local ...
Khurana Kamal K - - 2012
We evaluated dynamic telecytopathology for on-site-evaluation of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) samples of the pancreas. Realtime images of stained cytology smears were assessed by a cytopathologist while communicating with the on-site operator by telephone. A total of 55 consecutive cases was assessed; preliminary diagnoses of benign, atypical/suspicious and ...
Santos Mariana Dutra de Cássia Ferreira - - 2012
Linear epidermal nevus is an uncommon diagnosis of benign lesions of the oral cavity. It is characterized by a congenital malformation arising from the ectoderm cells, which are arranged according to a typical linear configuration known as Blaschko's lines. We report a case of linear epidermal nevus of oral cavity ...
Akbaba Müslime - - 2012
Dermoid and epidermoid cysts are choristomas that form due to the entrapment of epithelial remnants within the bony suture lines during embryologic development, around third and fifth week of gestation. Although these rare cysts, particularly the epidermoids, are most often seen in the cranial bones, they only constitute about 1% ...
Kim Sung Kang - - 2011
In cholangiographic techniques, the close relationship between choledochal cyst and anomalous union of pancreaticobiliary duct has attracted medical attention. There have been rare cases in which the papilla of Vater was found in a position other than its normal position, and such cases have been reported sporadically. However, such cases ...
Wu Xiu-Jie - - 2011
Paleopathological assessment of the late Middle Pleistocene archaic human cranium from Maba, South China, has documented a right frontal squamous exocranially concave and ridged lesion with endocranial protrusion. Differential diagnosis indicates that it resulted from localized blunt force trauma, due to an accident or, more probably, interhuman aggression. As such ...
Nogales Francisco F - - 2011
Nogales FF, Preda O & Nicolae A (2011) Histopathology Yolk sac tumours revisited. A review of their many faces and names We review the current knowledge on human yolk sac tumours (YSTs) 50 years after their initial description. Their complex nomenclature and histogenesis stress the fact that they are not a ...
Hong Yuan - - 2011
Septum pellucidum cysts are rare clinical findings. Although their optimal treatment remains controversial, large cysts causing hydrocephalus or neural compression should be treated surgically. However, spontaneous resolution can also occur. Herein, the authors present a case of a 38-year-old woman suffering from intermittent headache associated with an expanding cyst of ...
Udall Don N - - 2011
A 22-year-old male U.S. Navy airman with new nontender subcutaneous, 4-cm mass inferior to the right anterior costal margin was sent for routine biopsy. Sudden appearance of axillary lymph nodes prompted immediate excisional biopsy of the primary mass. Pathological evaluation was initially read as Onchocerca volvulus, the filarial nematode classically ...
Zayour Maya - - 2011
This article reviews congenital melanocytic nevi (CMN), which are present at birth or appear shortly thereafter, and their main histologic features. Several histologic variants and histopathologic criteria that differentiate CMN from other nevi, such as atypical or dysplastic nevi, and from nevoid malignant melanoma, are discussed. Histologic pitfalls in the ...
Islam Mohammed Nadimul - - 2011
Folliculosebaceous cystic hamartoma is a rare cutaneous hamartoma consisting of dilated folliculosebaceous structures interspersed within mesenchymal elements. These lesions may present as 0.5- to 3.0-cm papules or exophytic nodules and are usually solitary, symmetric, asymptomatic, dome-shaped, or even umbilicated. The usual location is the midface and scalp of adults. We ...
Martinez Rios Arellano Claudia - - 2011
BACKGROUND: Testicular epidermoid cyst is a rare benign tumor in children. Although this entity is widely described in adults in literature, there are no large series describing the pathological and radiological findings in children. Knowledge of the sonographic features seen in children may alter surgical treatment. OBJECTIVE: To describe the ...
Banikas Vasileios - - 2011
PURPOSE:: Branchial cleft cysts are among the most common causes for a congenital neck mass. Branchial cleft cyst carcinoma (BCCC) is a type of cancer that arises from cells within these cysts. Despite the distinct criteria that have been reported for its diagnosis, BCCC remains a controversial entity. CLINICAL REPORT:: ...
Cakarer Sirmahan - - 2011
The dentigerous cyst is a developmental odontogenic cyst, accounting for 10% of all cysts of the jaws. The treatment options are decompression, marsupialization, or enucleation regarding the features of the lesions. In this article, a case of a 17-year-old adolescent girl having a large mandibular dentigerous cyst associated with an ...
Tobino Kazunori - - 2011
BACKGROUNDS: Since Birt-Hogg-Dubé syndrome (BHDS) and lymphangioleiomyomatosis (LAM) share some clinical manifestations (multiple pulmonary cysts with pneumothorax, renal tumors, and sometimes skin lesions), the differential diagnosis of the two diseases becomes problem especially in female patients. This study aims to quantify pulmonary cysts in computed tomography (CT) of females with ...
Dahlberg Jessica A - - 2011
Horses with cranial rib abnormalities may exhibit severe acute lameness and may have unusual gait deficits characterized by forelimb abduction during protraction at the walk. Horses with caudal rib abnormalities may resent being saddled and ridden. In a retrospective evaluation of 20 horses with a documented rib lesion, 25 sites ...
Lee Jung-Hyun - - 2011
We report a case of a meconium pseudocyst secondary to ileal atresia and midgut volvulus. Initially, a single anechoic cyst was detected on prenatal sonography. The cyst gradually increased in size during the second trimester and eventually appeared as a large mass in the lower abdomen with echogenic content and ...
Blum Alain - - 2011
Neuropathies of the shoulder are considered to be entrapment syndromes. They are relatively common, accounting for about 2% of cases of sport-related shoulder pain. Many instances involve suprascapular neuropathy, but the clinical diagnosis is often delayed because of nonspecific symptoms. Classically, EMG is the gold standard investigation but MRI currently ...
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