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Jamjoom Lamia L Department of Radiology, King Abdul Aziz University Hospital, Jeddah, Saudi - - 2014
This pictorial essay illustrates, describes, and correlates computed tomographic findings of tracheal neoplasms with fiberoptic bronchoscopy findings. Corresponding computed tomography (CT) and bronchoscopy findings of common primary tracheal neoplasms; squamous cell papilloma, papillomatosis, squamous cell carcinoma, adenoid cystic adenoma, non-Hodgkin׳s lymphoma, and a secondary malignant neoplasm of the trachea; and ...
Maniar Kruti P KP Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Squamous cell carcinomas of the lower anogenital tract that are related to human papillomavirus (HPV) infection represent a significant disease burden worldwide. The diagnosis and management of their noninvasive precursors has been the subject of extensive study and debate over several decades, accompanied by an evolving understanding of HPV biology. ...
Xu Jun-Mei JM Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Tenth People's Hospital of Tongji University, Shanghai, - - 2014
The aim of the study described here was to evaluate the diagnostic performance of acoustic radiation force impulse (ARFI) elastography in the differential diagnosis between benign and malignant solid hypo-echoic thyroid nodules (SHTNs) on ultrasound. In this retrospective study, 183 histologically proven SHTNs in 159 patients were enrolled. Conventional US, ...
van Hoeij F B FB Department of Gastroenterology, St Antonius ziekenhuis, Nieuwegein, The Netherlands, - - 2014
In patients undergoing (18)F-FDG PET/CT, incidental colonic focal lesions can be indicative of inflammatory, premalignant or malignant lesions. The maximum standardized uptake value (SUVmax) of these lesions, representing the FDG uptake intensity, might be helpful in differentiating malignant from benign lesions, and thereby be helpful in determining the urgency of ...
Werner Rudolf A RA Department of Nuclear Medicine, Universitätsklinikum Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, - - 2014
Abundant expression of somatostatin receptors (SSTR) is frequently identified in differentiated neuroendocrine tumors and may serve as potential target for diagnostic imaging and treatment. This article discusses the "theranostic approach" of SSTR-targeting compounds including an overview of its role for diagnosis, staging and restaging, discussing its way to being established ...
Part Martina M Faculty of Medicine, Department of Dermatology and Venerology, Comenius University in Bratislava, Bratislava, - - 2014
Seborrheic keratoses are very common benign epidermal tumors. Despite the high frequency, the pathogenesis is still unknown. They are extremely rare in the genital area. The participation of human papilloma viruses (HPVs) in pathogenesis of seborrheic keratoses is being discussed. The aims of this case report are to inform about ...
Hatter Alyn D AD Department of Dermatology, Case Western Reserve University, Cleveland, - - 2014
: Langerhans cell histiocytosis (LCH) carries a prognosis, which ranges from benign to potentially fatal. There is currently little framework to decipher metrics, which predict the benign versus aggressive nature of LCH. We wanted to determine whether molluscum contagiosum virus (MCV) DNA could be isolated from a cutaneous lesion, demonstrating ...
Cohen Philip R PR Division of Dermatology, University of California San Diego, San Diego, - - 2014
: Granuloma annulare, a benign dermatosis of undetermined etiology, typically presents in a localized or generalized form. It has 3 distinctive histologic patterns: an infiltrative (interstitial) pattern, a palisading granuloma pattern, and an epithelioid nodule (sarcoidal granuloma) pattern. A man whose granuloma annulare skin lesions mimicked sarcoidosis is described. His ...
Shao Jun J Department of Ultrasound Diagnosis, Kunshan Hospital Affiliated to Jiangsu University, Suzhou, 215300, - - 2014
The aim of this study was to evaluate the value of ultrasound scores obtained by conventional ultrasonography and ultrasound elastography in the differentiation of benign and malignant thyroid nodules in Chinese patients. This study included 297 patients who were referred for surgery for compressive symptoms or suspicion of malignancy. Five ...
Juskevcius Darius D Institute of Pathology, University Hospital, Basel, - - 2014
Primary effusion lymphoma (PEL) is a rare form of aggressive B-cell lymphoma, which typically manifests as malignant effusion in the body cavities. However, extracavitary solid variants are also described. The aim of this study was to investigate copy number aberrations in two cases of solid PEL at their first occurrences ...
Hamdi M F MF Department of Trauma and Orthopaedic Surgery, F. Bourguiba University Hospital, 5000, Monastir, Tunisia, - - 2014
Osteoid osteoma (OO) is a slowly progressing benign osteoblastic tumour. In the hand, this tumour is rare. We propose a review of seventeen cases of OO of the phalanx and metacarpal bone. During the period, between 1998 and 2011, a total of seventeen OO in the hand were confirmed by ...
Moon Hee Jung HJ From the Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, 50 Yonse-ro, Seodaemun-gu, 120-752 Seoul, - - 2014
Purpose To evaluate the malignancy risks of thyroid nodules with nondiagnostic results at ultrasonography (US)-guided fine-needle aspiration biopsy (FNAB) and the criteria for selecting those for repeat US-guided FNAB according to the thyroid imaging reporting and data system (TIRADS). Materials and Methods This retrospective study was approved by the institutional ...
Trimboli Pierpaolo P Section of Endocrinology and Diabetology, Ospedale Israelitico, Via Fulda 14, 00148, Rome, Italy, - - 2014
Recently, the microhistologic evaluation by core needle biopsy (CNB) has been reported as high accurate to diagnose thyroid nodules with previous indeterminate or not adequate fine-needle aspiration cytology. In addition, sparse data have been reported regarding the use of CNB in other conditions. Aim of this review was to furnish ...
Randell Rebecca R School of Healthcare, University of Leeds, Leeds, LS2 9UT, UK, - - 2014
Performing diagnoses using virtual slides can take pathologists significantly longer than with glass slides, presenting a significant barrier to the use of virtual slides in routine practice. Given the benefits in pathology workflow efficiency and safety that virtual slides promise, it is important to understand reasons for this difference and ...
Killen Stacy A S SA Department of Pediatrics, Division of Pediatric Cardiology, Vanderbilt University, Nashville, Tennessee, - - 2014
Fetal cardiology is a rapidly evolving field. Imaging technology continues to advance as do approaches to in-utero interventions and care of the critically ill neonate, with even greater demand for improvement in prenatal diagnosis of congenital heart disease (CHD) and arrhythmias. Reviewing the advances in prenatal diagnosis of CHD in ...
Cotter José J José Cotter, Joana Magalhães, Francisca Dias de Castro, Mara Barbosa, Pedro Boal Carvalho, Sílvia Leite, Maria João Moreira, Bruno Rosa, Gastroenterology Department, Centro Hospitalar do Alto Ave, 4835-044 Guimarães, - - 2014
To evaluate whether virtual chromoendoscopy can improve the delineation of small bowel lesions previously detected by conventional white light small bowel capsule endoscopy (SBCE). Retrospective single center study. One hundred lesions selected from forty-nine consecutive conventional white light SBCE (SBCE-WL) examinations were included. Lesions were reviewed at three Flexible Spectral ...
Kocięcki Jarosław J Department of Ophthalmology, Karol Marcinkowski University of Medical Sciences, Poznań, Długa 1/2, Poland, - - 2014
Pathomechanism of lesions in the course of trichinellosis was discussed, representing a sum of immunopathologicaI, pathomorphological and biochemical phenomena. Particular attention was devoted to clinical pathology of the visual organ, which prevails at the acute stage of trichinellosis. In evaluation of clinical signs/symptoms manifested in the visual organ traits of ...
Mariscotti Giovanna G Dipartimento di Diagnostica per Immagini e Radioterapia, S.C. Radiologia Universitaria--Università di Torino, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Via Genova 3, 10126, Turin, Italy, - - 2014
The authors sought to compare the diagnostic performance of the Mammotome(®) and EnCor(®) vacuum-assisted breast biopsy (VABB) systems in the assessment of suspicious mammographic microcalcifications. Between January 2011 and July 2012, a total of 169 VABB were performed by stereotactic guidance on a prone table. The Mammotome(®) 11G (S1) or ...
Shimizu Kohei - - 2014
This paper proposes a new computer-aided method for skin lesion classification applicable to both melanocytic skin lesions (MSLs) and non-melanocytic skin lesions (NoMSLs). Computer-aided skin lesion classification has drawn attention as an aid for detection of skin cancers. Several researchers have developed methods to distinguish between melanoma and nevus, which ...
Spyropoulou G A GA Department of Plastic and Reconstructive Surgery, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, - - 2014
Benign lesions of the breast in total are much more frequent than malignant ones. However, there are no epidemiologic data on the prevalence of benign or malignant tumours of the nipple, and the bibliography on benign nipple tumours in general is limited. To present some rare cases of benign nipple ...
Yap Natalie N N Yap, Endocrinology, Royal North Shore Hospital, St Leonards, Australia - - 2014
The sensitivity of local recurrence detection in differentiated thyroid cancer is increased by measuring thyroglobulin in needle washouts (FNA-Tg) from lymph node fine-needle aspiration biopsies. Recent studies have proposed minimum diagnostic threshold values for FNA-Tg, and have reported interference from thyroglobulin antibodies, leading to low or false negative results. The ...
Chen Hong-Tan HT Hong-Tan Chen, Guo-Qiang Xu, Yi-Peng Chen, Li-Hua Chen, You-Ming Li, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, - - 2014
To investigate the diagnostic accuracy of endoscopic ultrasonography (EUS) for rectal neuroendocrine neoplasms (NENs) and the differential diagnosis of rectal NENs from other subepithelial lesions (SELs). The study group consisted of 36 consecutive patients with rectal NENs histopathologically diagnosed using biopsy and/or resected specimens. The control group consisted of 31 ...
Montgomery Marissa M MM Marissa M Montgomery, I Michael Leitman, Department of Surgery, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY 10003, United - - 2014
The evaluation of ascites in patients with known or suspected malignancy is a critical aspect of preoperative staging. Endoscopic evaluation by ultrasound of low volume ascites and sampling of the ascitic fluid by endoscopic ultrasound guided paracentesis (EUS-P) is both a sensitive and specific modality for the determination of peritoneal ...
Nagaoka T T Waseda Research Institute for Science and Engineering, Waseda University, Shinjuku, Tokyo, - - 2014
The morphology of pigmented skin lesions (PSLs) is predominantly a result of varying concentrations and distributions of pigmented molecules such as melanin and hemoglobin. Based on these differences and the fact that their information is contained in cutaneous spectra, a hyperspectral imager (HSI) for pigmented melanoma and a single discrimination ...
Björnsdóttir Sigríður - - 2014
BackgroundOral lesions related to the use of the bit and bridle are reported to be common findings in horses worldwide and represent an important animal welfare issue. In order to provide an overview of bit-related lesions in Icelandic competition horses, a field examination of the rostral part of the oral ...
Izumo Takehiro T Department of Endoscopy, Respiratory Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan - - 2014
Endobronchial ultrasound elastography is a new technique for describing the stiffness of tissue during endobronchial ultrasound-guided transbronchial needle aspiration. The aims of this study were to evaluate the utility of endobronchial ultrasound elastography for mediastinal and hilar lymph nodes, and to compare the elastographic patterns of lymph nodes with results ...
Kanno Atsushi A Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, - - 2014
Autoimmune pancreatitis (AIP) is characterized by diffuse pancreatic enlargement and irregular narrowing of the main pancreatic duct (MPD). IgG4-related sclerosing cholangitis (IgG4-SC) associated with AIP frequently appears as a bile duct stricture. Therefore, it is important to differentiate AIP and IgG4-SC from pancreatic cancer and cholangiocarcinoma or primary sclerosing cholangitis, ...
Moscarella E E Dermatology and Skin Cancer Unit, Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia, - - 2014
Spitz nevi may present a wide spectrum of morphologies. Histopathologically, many variants, including desmoplastic, angiomatoid, verrucous/polypoid, plexiform, pagetoid, halo, myxoid, granulomatous, and tubular Spitz nevi, have been described. Clinical and dermoscopic features of these unusual variants of Spitz nevi have been rarely reported. The aim of this study is to ...
Chen Haijun H College of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China; Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United - - 2014
Despite tremendous advances in the targeted therapy for various types of hematological malignancies with successful improvements in the survival rates, emerging resistance issues are startlingly high and novel therapeutic strategies are urgently needed. In addition, chemoprevention is currently becoming an elusive goal. Plant-derived natural products have garnered considerable attention in ...
Lin Peiliang P Department of Vascular and Thyroid Surgery, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, Guangdong, 510080, - - 2014
This meta-analysis aimed to assess the performance of shear wave elastography (SWE) in the identification of malignant thyroid nodules. Web of Science, Scopus, PubMed, and the references of narrative reviews were searched for relevant studies with a publication date through October 2013. The methodological quality was assessed using QUADAS tools. ...
Wang Tingting - - 2014
Nasal chondromesenchymal hamartoma (NCMH) is an extremely rare benign tumor, primarily diagnosed in young infants and children and it often simulates malignant tumors on imaging. We present computerized tomography and magnetic resonance imaging findings of two nasal chondromesenchymal hamartomas in a 5-year-old boy and a 6-week-old girl. NCMH is a ...
Howitt Brooke E BE Department of Pathology, Women's and Perinatal Division, Brigham and Women's Hospital, Boston, - - 2014
Müllerian adenosarcoma (MA) is a mixed Müllerian neoplasm composed of malignant stroma and benign epithelium. Endometrial and endocervical polyps are common entities in surgical pathology practice and most can be readily distinguished from MA; however, some have overlapping features, causing diagnostic confusion. In this study, we examined uterine polyps falling ...
Gürsoy Mustafa Ozan MO Department of Cardiology, Gaziemir State Hospital, Izmir, - - 2014
Prosthetic valve thrombosis (PVT) is a potentially life-threatening complication of heart valve replacement. Early diagnosis is crucial for the prevention of significantly morbid and lethal complications. Cinefluoroscopy (CF) and echocardiography have been widely used for diagnosing PVT. In recent years, the role of CF has declined since the introduction of ...
Sousa Anastácio Q AQ School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil; Hospital São José for Infectious Diseases, Fortaleza, Ceará, Brazil; School of Medicine, Fortaleza, Ceará, Brazil; State University of Ceará School of Medicine, Fortaleza, Ceará, Brazil; University of Virginia School of Medicine, Charlottesville, Virginia - - 2014
A modified imprint method, Press-Imprint-Smear, was compared with histopathology for the diagnosis of cutaneous leishmaniasis. Amastigotes were seen in 69 (92%) of 75 individuals in one or both assays. The Press-Imprint-Smear was positive in 85.3%, and histopathology was positive in 44%. Press-Imprint-Smear is a rapid and relatively sensitive method for ...
Chik William W B WW Cardiology Department, Westmead Hospital & Sydney Medical School, University of Sydney, Sydney, Australia - - 2014
-Cardiac and respiratory movements cause catheter instability. Lateral catheter sliding over target endocardial surface can lead to poor tissue contact and unpredictable lesion formation. We describe a novel method of overcoming the effects of lateral catheter sliding movements by using an electrogram-gated pulsed power ablation. -All ablations were performed on ...
Jain D D Department of Pathology, All India Institute of Medical Sciences, New Delhi, - - 2014
The cell block (CB) is a routine procedure in cytopathology that has gained importance because of its pivotal role in diagnosis and ancillary studies. There is no precise review in the published literature that deals with the various methods of preparation of CB, its utility in diagnosis, immunocytochemistry (ICC) or ...
Spick Claudio C From the Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, - - 2014
Purpose To evaluate the diagnostic utility of second-look ultrasonography (US) in the assessment of lesions identified at breast magnetic resonance (MR) imaging. Materials and Methods A systematic review of the PubMed database for articles published up to January 6, 2013, was performed by using predefined search terms applied in a ...
Preuß Matthias M Department of Neurosurgery, Pediatric Neurosurgery, University Hospital Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany, - - 2014
We present a case of a preterm boy of 29 gestational weeks with complicated posthemorrhagic hydrocephalus who developed a retroclival cyst extending to the upper cervical spinal canal and leading to brainstem compression. At the age of 2 months, third ventriculocisternocystostomy (ETVCC) resulted in temporary relief but was followed by reclosure ...
Antoine Jean-Christophe JC Centre de Référence Maladies Neuromusculaires Rares Rhône-Alpes, CHU de Saint-Etienne, Saint-Étienne, France, - - 2014
There are no validated criteria for the diagnosis of sensory neuronopathy (SNN) yet. In a preliminary monocenter study a set of criteria relying on clinical and electrophysiological data showed good sensitivity and specificity for a diagnosis of probable SNN. The aim of this study was to test these criteria on ...
Miyabe Katsuyuki K Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan, - - 2014
Various methods to evaluate immunohistochemical staining (IHC) for the diagnosis of type 1 autoimmune pancreatitis (AIP) have been proposed. Our goal was to determine the most useful IHC method for the diagnosis of AIP. Specimens of AIP (18 patients), chronic pancreatitis (CP, 24 patients), and pancreatic ductal adenocarcinoma (PDA, 45 ...
Cornelis F F Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA, - - 2014
We sought to evaluate the safety and the diagnostic success rate of percutaneous biopsies performed under intra-procedural (18) F-deoxyglucose (FDG) positron-emission tomography/computed tomography (PET/CT) guidance for lesions difficult to see with conventional cross-sectional imaging. From 2011 to 2013, consecutive clinically indicated percutaneous PET/CT-guided biopsies of 106 masses (mean size, 3.3 cm; range, ...
Dorrius Monique D MD University Medical Center Groningen, Center for Medical Imaging - North East Netherlands, University of Groningen, Groningen, The Netherlands, - - 2014
To evaluate the effect of the choice of b values and prior use of contrast medium on apparent diffusion coefficients (ADCs) of breast lesions derived from diffusion-weighted imaging (DWI), and on the discrimination between benign and malignant lesions. A literature search of relevant DWI studies was performed. The accuracy of ...
Hameed Meera M Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, - - 2014
Sarcomas are rare and heterogeneous neoplasms of mesenchymal tissues with diverse morphologies and clinical behavior. In the last few years, the discovery of specific genetic aberrations in these tumors has allowed better classification and understanding of mechanisms driving their pathogenesis. While the majority of sarcomas are still treated by traditional ...
Gerhard Rene R Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, and Department of Pathology, University Health Network, Toronto, Ont., - - 2014
Objective: Fine-needle aspiration (FNA) is a safe and cost-effective technique for the diagnosis of breast lesions, especially when correlated with clinical and imaging studies. However, the success of breast FNA is highly dependent on the adequate preparation of cytological conventional smears (CS). The liquid-based cytology (LBC) technique consists of an ...
Nagai Kengo - - 2014
Recent technological advances have stimulated the development of endoscopic optical biopsy technologies. This study compared the accuracy of endoscopic diagnosis using magnifying narrow-band imaging (NBI) and histologic diagnosis of esophageal squamous lesions. Patients at high risk for esophageal squamous cell carcinoma were examined with endoscopy and subsequent biopsy. The lesions ...
Liu Shu S Department of Endocrinology, the First Affiliated Hospital of Xi'an Jiaotong University Health Science Center, Xi'an 710061, PR - - 2014
Fine-needle aspiration biopsy remains the mainstay of the preoperative examination of thyroid nodules; however, it does not provide a definite diagnosis in up to 25% of nodules. Considerable studies have been done to find molecular markers to resolve this diagnostic dilemma. The aim of this study was to establish the ...
Mottolese C C Neurological and Neurosurgical Hospital « P. Wertheimer », Pediatric Neurosurgery E, 59, boulevard Pinel, 69677 Bron, France. Electronic address: - - 2014
The knowledge of the incidence of pineal tumours is important not only for diagnostic care but also for its therapeutic programme. We reviewed the incidence of pineal tumours reported in literature in an attempt to establish if a difference existed between pineal gland tumours and the pineal region tumours as ...
Mehrmohammadi Mohammad - - 2014
In clinical practice, an overwhelming majority of biopsied thyroid nodules are benign. Therefore, there is a need for a complementary and noninvasive imaging tool to provide clinically relevant diagnostic information about thyroid nodules to reduce the rate of unnecessary biopsies. The goal of this study was to evaluate the feasibility ...
Andersson Manne M Department of Clinical and Experimental Medicine, Surgery, Faculty of Health Sciences, Linköping University, Linköping, Sweden, - - 2014
The diagnosis of appendicitis is difficult and resource consuming. New inflammatory markers have been proposed for the diagnosis of appendicitis, but their utility in combination with traditional diagnostic variables has not been tested. Our objective is to explore the potential of new inflammatory markers for improving the diagnosis of appendicitis. ...
Wrobel Gabriel G Department of Anthropology, Michigan State University, - - 2014
A Maya burial of a late adolescent (Burial 98-3) found in the rockshelter entrance of Actun Uayazba Kab (AUK), Belize, displays a combination of lesions that is consistent with scurvy. Signs include large, active lesions on the posterior surfaces of maxilla; relatively mild porotic hyperostosis along the midline of the ...
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