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Nasit Jitendra G JG From the Department of Pathology, Pandit Deendayal Upadhyay Government Medical College and Hospital, Gujarat, India. - - 2014
Well-differentiated papillary mesothelioma of the peritoneum (WDPMP) is an uncommon subtype of epithelioid mesothelioma. Usually, WDPMP has a benign course, while a few patients have multiple recurrence and malignant transformation on long-term follow-up. The histology of WDPMP has been well studied compared with the cytology. Although accurate diagnosis is based ...
Chen Xin X Department of Radiology, Wuhan Asia Heart Hospital, Wuhan, Hubei 430022, P.R. - - 2014
The aim of this study was to evaluate the clincal value of multi-slice spiral computed tomography (MSCT) in the diagnosis of double aortic arch (DAA) and analyze the associated angiography and 3D reconstruction imaging to increase the accuracy of DAA diagnosis. Clinical and imaging data from 15 patients diagnosed with ...
Sousa Michele Cardoso MC Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP, Univ. Estadual Paulista, São José dos Campos, São Paulo 12245-000, - - 2014
The present study aimed to investigate the efficiency of exfoliative cytology by correlating the clinical lesions of oral squamous cell carcinoma (OSCC) with exfoliative cytology and histopathological findings. Cases of OSCC diagnosed between 1984 and 2010 were analyzed. The inclusion criteria for the present study were the availability of detailed ...
Steward David L DL Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0528, USA; Division of Endocrinology, Department of Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0528, - - 2014
Thyroid fine-needle aspiration biopsies are cytologically indeterminate in 15% to 30% of cases. When cytologically indeterminate thyroid nodules undergo diagnostic surgery, approximately three-quarters prove to be histologically benign. A negative predictive value of more than or equal to 94% for the Afirma Gene Expression Classifier (GEC) is achieved for indeterminate ...
Tsao Gabriel J GJ Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, 2380 Sutter Street, 2nd Floor, San Francisco, CA 94115, - - 2014
Fine needle aspiration biopsy (FNA) is the key step in selecting most patients with thyroid nodules for or against surgery. Accurate acquisition of cytologic samples from suspicious lesions is achieved by adding ultrasound guidance to optimize targeting as well as to enable sampling from nonpalpable lesions. This article discusses the ...
Tuluc Madalina M Department of Pathology, Jefferson University Hospital, 132S 10th Street, Main Building, Philadelphia, PA 19107, USA. Electronic address: - - 2014
This article covers, in a comprehensive way, thyroid cytopathology. The Bethesda System for Reporting Thyroid Cytology is reviewed, with emphasis on the atypical and indeterminate diagnostic categories. Immunohistochemistry stains and molecular tests panels applicable to cytology specimens are described.
Reserva Jeave L JL *Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL; †Department of Pathology, University of California at San Diego, San Diego, CA; ‡Department of Pathology and Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR; §DermLogic, PLLC, PA, North Little Rock, AR; and ‖Department of Pathology, Orlando Health, Orlando, - - 2014
: Cutaneous ciliated cysts (CCC) are rare benign cysts known to occur in the lower extremities of females of reproductive age. Currently, there are 2 theories that attempt to explain the histogenesis of this rare entity. The theory of Mullerian heterotopia provides a plausible histogenetic explanation for the vast majority ...
Rago Teresa T Department of Clinical and Experimental Medicine, Section of Endocrinology, University of Pisa, - - 2014
Among several ultrasound patterns, thyroid nodule hypoechogenicity, spot microcalcifications, and an absent halo sign are used for predicting increased risk of thyroid malignancy. The predictive value of ultrasound, however, increases at the expense of its sensitivity, and malignancy is predicted with high specificity only when multiple ultrasound features are simultaneously ...
Machan Salma S Departments of *Dermatology, and †Pathology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain; and ‡Departments of Dermatology and Pathology, and the UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, - - 2014
: Giant congenital melanocytic nevi (GCMNs) represent a distress to patients for 2 reasons: one is disfigurement, and the other is the increased risk of developing secondary melanocytic tumors, such as benign proliferative nodules (BPNs) and malignant melanoma (MM). BPN present as a rapid growth nodule arising within a congenital ...
Rooper Lisa M LM Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, - - 2014
No consensus exists regarding minimum fluid volume for adequacy of benign pleural effusion specimens. Although any volume is acceptable if cytologic findings are malignant, the distinction between the absence of disease and false-negativity is not straightforward in low-volume specimens. Recent literature has offered conflicting results regarding what minimum volume is ...
Traeger-Synodinos Joanne J Department of Medical Genetics, Choremeio Research Laboratory, University of Athens, St Sophia's Children's Hospital, Athens, - - 2014
Haemoglobinopathies constitute the commonest recessive monogenic disorders worldwide, and the treatment of affected individuals presents a substantial global disease burden. Carrier identification and prenatal diagnosis represent valuable procedures that identify couples at risk for having affected children, so that they can be offered options to have healthy offspring. Molecular diagnosis ...
Uppal Vishal V Department of Anesthesiology and Perioperative Medicine, London Health Sciences Centre, University of Western Ontario, 339 Windermere Road, London, ON, N6A 5A5, Canada, - - 2014
During peripheral nerve block procedures, needle visibility decreases as the angle of needle insertion relative to skin increases due to loss of reflective signals. The primary aim of our study was to compare the effect of beam steering on the visibility of echogenic and non-echogenic block needles. PAJUNK(®) non-echogenic and ...
Pushker Neelam N Oculoplasty and Paediatric Ophthalmology Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, - - 2014
The aim of the study was to study the clinical, radiological and histopathological characteristics of orbital schwannomas. It is a retrospective study conducted at a tertiary eye care hospital. A review of histopathological records of the orbital tumors operated between 1993 and 2011 was done. The clinical, imaging and histopathological ...
Yang Jiansheng J Department of Radiology, Zhejiang Provincial People's Hospital, No. 158, Shangtang Road, Hangzhou, Zhejiang, China, - - 2014
Objectives: This meta-analysis is to determine the overall diagnostic yield of CT-guided TNB of GGO lesions. Methods: A MEDLINE search was performed using "ground-glass opacity" crossed with "core biopsy" and "needle biopsy." Test performance characteristics with the use of forest plots, summary receiver operating characteristic (SROC) curves, and bivariate random ...
Izumo Takehiro T Department of Endoscopy, Respiratory Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan - - 2014
Endobronchial ultrasound-guided transbronchial needle aspiration is widely used for mediastinal and hilar lesions. Histologic specimens from this procedure are important for specific diagnosis and targeted therapy. Studies on the traditional endobronchial ultrasound-guided transbronchial needle aspiration needles reported yields of only 50-60% for diagnostic histologic specimens. Recently, a new needle has ...
Luo Yanji Y Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong, China, 510080, - - 2014
We aimed to evaluate the multi-slice computed tomography (MSCT) features of pancreatic neuroendocrine neoplasms (P-NENs) and analyse the correlation between the MSCT features and pathological classification of P-NENs. Forty-one patients, preoperatively investigated by MSCT and subsequently operated on with a histological diagnosis of P-NENs, were included. Various MSCT features of ...
Sun Jian-Jun JJ Department of Neurosurgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China, - - 2014
This prospective study analyzes clinical characteristics and outcomes of sacral extradural spinal meningeal cysts (SESMC) without spinal nerve root fibers (SNRF) undergoing neck transfixion. Using the relationship between the cysts and SNRF, SESMCs were divided into two types: cysts with SNRF known as Tarlov cysts and cysts without. If the ...
Oikonomou Anastasia A Cardiothoracic Imaging Division, Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, - - 2014
This review aims to provide a literature update focused on the role of imaging in the diagnosis, prognosis and quantification of interstitial lung diseases (ILDs). Special emphasis is given in the management of atypical cases and in the multidisciplinary team approach in reaching the diagnosis of the various ILDs. Accumulated ...
La Rosa Stefano S Department of Pathology, Ospedale di Circolo, Varese, - - 2014
Gastric neuroendocrine neoplasms (NENs) are a heterogeneous group of tumours showing different clinicopathological features and behaviour, implying a wide spectrum of therapeutic options. They are currently classified using the 2010 WHO classification of digestive neuroendocrine neoplasms into G1-neuroendocrine tumours (NETs), G2-NETs, neuroendocrine carcinomas (NECs) and mixed adenoneuroendocrine carcinomas (MANECs). However, ...
Trimboli P P Section of Endocrinology and Diabetology, Ospedale Israelitico, Rome, Italy; Department of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, - - 2014
The early detection of medullary thyroid carcinoma (MTC) can improve patient prognosis, because histologic stage and patient age at diagnosis are highly relevant prognostic factors. As a consequence, delay in the diagnosis and/or incomplete surgical treatment should correlate with a poorer prognosis for patients. Few papers have evaluated the specific ...
Conway Gerard S GS G Conway, University College London Hospitals, Department of Endocrinology, London, NW1 2PQ, United - - 2014
Background: There is evidence for differences between endocrinologists and other specialists in their approach to diagnosis and management of the polycystic ovary syndrome (PCOS). Objective: A mailed survey consisting of a simple questionnaire aiming to understand current practice for diagnosis and management of the PCOS by specialists across Europe. Methods: ...
Feng Lei L *MD †MM ‡PhD Departments of Ophthalmology (LF, TG, BL, YY) and Pathology (BL), the Second Hospital Affiliated to Zhejiang University, Hangzhou, Zhejiang, China; and Department of Ultrasound in Medicine, Sir Run Run Shaw Hospital Affiliated to Zhejiang University, Hangzhou, Zhejiang, China - - 2014
To describe a case of uveal melanoma in the peripheral choroid masquerading as chronic uveitis and to raise awareness about malignant masquerade syndromes. A 36-year-old Chinese woman presented from an outside ophthalmologist with a 6-month history of unilateral chronic uveitis unresponsive to medical therapy in the left eye. She was ...
Gerscovich Eugenio O EO Department of Radiology, University of California, Davis Health System, 4860 Y Street, Suite 3100, Sacramento, CA, - - 2014
Splenic dermoids are rare, with few published case reports and no ultrasound images in the English literature. We report the case of a 57-year-old woman with that diagnosis and illustrate it with ultrasound, CT, and pathology images. We discuss the differential diagnosis of solid splenic lesions. © 2014 Wiley Periodicals, ...
de Bazelaire C C Inserm U 728, Department of Diagnostic and interventional radiology, Saint-Louis Hospital, Paris VII University, 1, avenue Claude-Vellefaux, 75475 Paris cedex 10, France. Electronic address: - - 2014
Imaging-guided percutaneous biopsies in patients in oncology provide an accurate diagnosis of malignant tumors. Percutaneous biopsy results are improved by correct use of sampling procedures. The risks of percutaneous biopsy are low and its complications are generally moderate. These risks can be reduced using aids such as blund tip introducers, ...
Serrani M M Department of Medical and Surgical Sciences, University of Bologna/Hospital of Imola, Italy - - - 2014
Endoscopic ultrasound is a very accurate imaging technique with a relevant clinical impact in the diagnosis and staging of various conditions such as pancreaticobiliary lesions, esophageal cancer, lung cancer, submucosal lesions and lymph nodes. Despite its increasing importance in everyday clinical routine, endoscopic ultrasound outcomes are still highly operator dependent ...
Lee Kwang Hyuck KH From the *Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine; †Yonsei University College of Medicine; ‡Seoul National University College of Medicine, Seoul; §National Cancer Center, Ilsan; ∥School of Medicine, Catholic University of Daegu, Daegu; ¶College of Medicine, Wonkwang University, Iksan; #College of Medicine, Soonchunhyang University, Bucheon; and **College of Medicine, The Catholic University of Korea, Seoul, South - - 2014
We evaluated the accuracy of a new endoscopic ultrasonography (EUS) scoring system to predict malignancy in branch duct-type intraductal papillary mucinous neoplasms (BD-IPMNs). We performed a retrospective multicenter study of patients who underwent EUS within 3 months before surgery and were diagnosed as having BD-IPMNs by postoperative pathologies at 8 ...
Rossi Esther Diana ED Division of Anatomic Pathology and Histology, Agostino Gemelli School of Medicine, Catholic University of Sacred Heart, Rome, - - 2014
Objective: Thyroid nodules are a common finding in the general population, including both nonneoplastic and neoplastic entities. Fine-needle aspiration cytology (FNAC) is the first tool for evaluating thyroid nodules. In spite of its high diagnostic accuracy, 25% of nodules result in the category of follicular neoplasms (FN), with varying risk ...
Wright Nicholas A NA Centre for Tumour Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK, EC1 - - 2014
In the 100 years since the publication of Boveri's manuscript, 'Concerning the origin of human tumours', we have seen many advances in our understanding of how tumours originate, develop and progress. However: reading this article now, it is possible to find conclusions, or more often predictions, of what we now ...
Shieh Frederick K FK Frederick K Shieh, Harshit S Khara, Matthew J Shellenberger, Amitpal S Johal, David L Diehl, Department of Gastroenterology and Nutrition, Geisinger Medical Center, Danville, PA 17822, United - - 2014
To determine if a new brush design could improve the diagnostic yield of biliary stricture brushings. Retrospective chart review was performed of all endoscopic retrograde cholangiopancreatography procedures with malignant biliary stricture brushing between January 2008 and October 2012. A standard wire-guided cytology brush was used prior to protocol implementation in ...
Kamisah Yusof Y Department of Pharmacology - - 2014
Abstract Context: Many scientific reports have shown the involvement of oxidative stress and inflammation as well as diminished gastroprotective substances in the pathogenesis of gastric lesions using various models. Therefore, treatment with antioxidants like tocopherol and tocotrienol may afford beneficial effects in attentuating the formation of the gastric lesions. Objective: ...
Wang Yihong - - 2014
We encountered an extremely rare case of multiple pulmonary sclerosing hemangiomas (PSH) with extensive neuroendocrine lesions, including pulmonary neuroendocrine cell (PNC) hyperplasia, multiple carcinoid tumorlets and typical carcinoid tumors within one pulmonary lobe. To the best of our knowledge, this is the first reported case in the English medical literature ...
Laganà Antonio Simone AS Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Via C. Valeria 1, 98125, Messina, Italy, - - 2014
To assess the concordance between the presumed diagnosis obtained with the 3D sonohysterography (SHG) and with the diagnostic hysteroscopy (HYS); to determine whether the 3D SHG has the accuracy needed to be considered as a diagnostic screening standard in cases of suspected endouterine pathology. We selected 224 patients who voluntarily ...
Wan Hao-Guang HG Department of Interventional Radiology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu 221002, PR - - 2014
Osteopontin (OPN) has been reported as one of the most promising markers for hepatocellular carcinoma (HCC). The goal of this meta-analysis was to evaluate the clinical value of the plasma OPN versus alpha-fetoprotein (AFP) in the diagnosis of HCC. A comprehensive literature search of PubMed, Foreign Medical Journal Service, Chinese ...
Nampoothiri Sheela S Department of Pediatric Genetics, Amrita Institute of Medical Sciences and Research Center, Cochin, Kerala, - - 2014
We report on a series of 514 consecutive diagnoses of skeletal dysplasia made over an 8-year period at a tertiary hospital in Kerala, India. The most common diagnostic groups were dysostosis multiplex group (n = 73) followed by FGFR3 (n = 49) and osteogenesis imperfecta and decreased bone density group (n = 41). Molecular confirmation was ...
Chacon A H AH Faculty, Department of Dermatology & Cutaneous Surgery, Orlando Regional Medical Center, University of Central Florida College of Medicine, Orlando - - - 2014
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon, benign condition characterized by multiple benign angiomatous nodules or plaques. Cutaneous lesions can be painful, pruritic, pulsatile, or potentially disfiguring resulting in significant morbidity. ALHE is a pathologic diagnosis featuring proliferations of capillary sized vessels with epithelioid endothelial cells surrounded by larger, ...
Del Corso Giacomo G Bellaria Hospital, University of Bologna, Bologna, Italy - - 2014
Background. Cysts of the jaws (JCs) are an important topic of oral pathology, but few epidemiological data are present in the literature, in particular about the potential of recurrence. The aim of this study was to describe a case series of JCs from a single institution, evaluating the frequency, the ...
Carter Yvette Y Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, Madison, WI, - - 2014
Thyroglossal duct remnants (TGDRs) account for more than 70% of anterior neck masses in children and 7% in adults; however, cancer is identified in only 1-2% of the cases. The diagnosis of a TGDR is based on clinical manifestation of a painless, anterior neck swelling, which elevates with swallowing. Cytological ...
Vega Rafael A RA Department of Neurosurgery, Virginia Commonwealth University, Richmond, Va., - - 2014
Background: Intradiploic dermoid cysts represent 0.04-0.7% of cranial tumors. Fewer than 20 cases of dermoid cysts occurring in the lateral frontotemporal region with a sinus tract and bony involvement are described, only 7 with intracranial extension. We present the first report of such a lesion arising within the lateral coronal ...
Shimizu Ikuo I Department of Hematology, Nagano Red Cross Hospital, Nagano-city, Nagano, Japan; Center for Medical Education, Shinshu University School of Medicine, Matsumoto, Nagano, - - 2014
Although pathological diagnosis is essential for managing malignant lymphoma, intraabdominal lesions are generally difficult to approach due to the invasiveness of abdominal surgery. Here, we report the use of percutaneous image-guided coaxial core-needle biopsy (CNB) to obtain intraabdominal specimens for diagnosing intraabdominal lymphomas, which typically requires histopathological and immunohistochemical evaluation. ...
Pabuccu E G EG Department of Obstetrics and Gynecology, Ankara University School of Medicine , Ankara , - - 2014
Atypical squamous cells 'cannot exclude high-grade squamous epithelial lesion' (ASC-H) cytology represents clear risk and has been a controversial issue in clinical practice. The objective of this study is to investigate the diagnostic performance of p16(INK4A) immunohistochemistry (IHC) among ASC-H Pap smears in predicting high-grade cervical intraepithelial lesions. Decolourisation and ...
Pagni Fabio F Department of Surgery and Translational Medicine, Section of Pathology, University Milan Bicocca, San Gerardo Hospital, 20900, Monza, Italy, - - 2014
The recent increase in the detection of papillary thyroid carcinoma (PTC) has been influenced by the finding of incidental tumours. To this group, carcinomas measuring less than 1 cm (the so-called microcarcinomas) as well as those above 1 cm belong. Analyzing a case series from our own experience, this paper focuses on ...
Nour-Eldin Nour-Eldin A NE Institute for Diagnostic and Interventional Radiology, Johan Wolfgang Goethe - University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Diagnostic and Interventional Radiology Department, Cairo University Hospital, Cairo, Egypt. Electronic address: - - 2014
To evaluate the risk factors involved in the development of pulmonary hemorrhage complicating CT-guided biopsy of pulmonary lesions in coaxial and non-coaxial techniques. Retrospective study included CT-guided percutaneous lung biopsies in 650 consecutive patients (407 males, 243 females; mean age 54.6 years, SD: 5.2) from November 2008 to June 2013. ...
Moshrefi Shawn S From the Department of Plastic Surgery, University of California, San Diego, San Diego, - - 2014
Primary cutaneous γδ T-cell lymphoma and hemophagocytic syndrome (HPS) is a very rare disease process with only 41 cases of this type of lymphoma published to date. We report the case of a 56-year-old woman who developed high-grade fevers and multiple nonhealing bilateral lower extremity ulcers associated with a recent ...
Weigner Julie J Pathology North, Hunter, John Hunter Hospital, Newcastle, N.S.W., - - 2014
Background: Fine-needle aspiration (FNA) of difficult breast lesions often results in an atypical (C3) report. The assortment of outcomes generated by C3 reports varies widely, and this has given rise to different clinical management pathways. Objective: To identify and objectively assess microscopic features associated with atypical/C3 breast FNA cases. Materials ...
Chander Bal B Department of Pathology, HIMACHAL PRADESH, - - 2014
Objective: To present and critically examine the spectrum of chondrocutaneous branchial remnants or accessory pinna, including rare case of bilateral cervical lesions, and to explain the basis of the biological behavior. Material and Method: Five cases of pediatric chondrocutaneous branchial remnants or accessory pinna were included. The ratios of the ...
Sahin Mustafa M Endocrinology and Metabolism Department, Ankara University School of Medicine, İbni Sina Hastanesi Ek Bina M-blok Kat:1, 06100, Sıhhıye, Ankara, Turkey, - - 2014
Elastography is a method which assesses the risk of the malignancy and provides information about the degree of hardness in tissue. Hashimoto's thyroiditis, autoimmune lymphocytic infiltration and fibrosis, is considered to be a very common disease that is able to change the hardness of the tissue. The diagnostic value of ...
Cinotti Elisa E Department of Dermatology, University Hospital of St-Etienne, Saint-Etienne, France. Electronic address: - - 2014
Handheld in vivo reflectance confocal microscopy (IVCM) is a new imaging method that allows noninvasive diagnosis of cutaneous tumors but to date it has not been used in the study of eyelid tumors. We sought to evaluate the suitability of IVCM for eyelid margin tumors. We prospectively evaluated the IVCM features ...
Bretschi Maren M Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, - - 2014
Aim of the study was to compare between volumetric and unidimensional approaches for treatment response monitoring in a nude rat model of experimental bone metastases. For the volumetric approach, an automated segmentation algorithm of osteolytic lesions was introduced and compared to manual volumetry. Nude rats bearing osteolytic metastases were treated ...
Partridge Savannah C SC Department of Radiology- University of Washington, Seattle Cancer Care Alliance, 825 Eastlake Avenue East, G3-200, Seattle, WA 98109-1023. Electronic address: - - 2014
Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) scanning protocols vary widely. The purpose of this study was to determine the effects of postcontrast timing on delayed-phase lesion kinetics assessment and ability to discriminate malignant from benign lesions. Following institutional review board approval, we retrospectively reviewed all lesions assessed on magnetic ...
Tregnago Aline C AC Department of Anatomic Pathology, A.C. Camargo Cancer Center, São Paulo, - - 2014
Background: Melanocytomas are rare pigmented primary lesions of the central nervous system arising from melanocytes of leptomeninges. They occur most frequently in the posterior fossa, Meckel's cave or along the cervical and thoracic spinal cord. Orbital melanocytomas have been rarely reported. Nevus of Ota is a melanocytic lesion that can ...
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