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Genta Robert M RM *Miraca Research Institute, Miraca Life Sciences, Irving †Departments of Pathology and Medicine, Veterans Affairs North Texas Health Care System ‡The University of Texas Southwestern Medical Center, Dallas, - - 2014
External influences, referred to as suprahistologic elements, may modulate pathologists' interpretation of morphologic findings. These elements can be divided into those that are loosely evidence based and exert a desirable influence on the diagnosis and those that arise from emotional, sometimes irrational perceptions not rooted in objective evidence. The latter, ...
Akin Cem C Harvard Medical School, Director, Mastocytosis Center, Brigham and Women's Hospital, Harvard Medical School, 1 Jimmy Fund Way, Room 626B, Boston, MA 02115, USA. Electronic address: - - 2014
Mastocytosis is characterized by accumulation of pathologic mast cells in tissues. Most patients with mastocytosis experience mast cell activation symptoms in response to various triggers. The diagnosis of mastocytosis should be made from objective pathologic findings. Modern diagnostic criteria and classification of mastocytosis were proposed in 2000 by an international ...
Ring Hans Christian HC Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Copenhagen, - - 2014
Self harm is a great diagnostic and treatment challenge. In addition, psychocutaneous conditions are rare in the pediatric population and may therefore be misdiagnosed. Dermatitis artefacta is a psychocutaneous syndrome, which is a subgroup of the general spectrum of self-inflicted skin lesions. Dermatitis artefacta encompasses an array of different clinical ...
Lee Hee Young HY Department of Radiology, Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
In case of mucinous adenocarcinoma (MA), cytologic atypia is usually mild to moderate, or may be absent in some cases, incurring a diagnostic pitfall in recognising MA in small tissue biopsy and cytology specimens. The purpose of this study was to evaluate the diagnostic accuracy of transthoracic fine needle aspiration ...
Brat Daniel J DJ Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA, - - 2014
1. What are the most important diagnostic considerations in reporting progressive glioblastoma? These recommendations apply to adults with progressive glioblastoma RECOMMENDATIONS : LEVEL III: For patients who undergo biopsy or neurosurgical resection at the time of radiologic or clinical progression, it is recommended that the pathologist report the presence and ...
Cimen Dilay D University of Kirikkale, Faculty of Medicine, Department of Pulmonary - - 2014
Round Pneumonia is a rare subtype of lobar pneumonia which arises due to a developmental defect in connective tissues (pores of Köhn and channels of Lambert). The pathogenesis of round pneumonia is unknown. As a result of this developmental defect, dissemination of infection is limited and remained in a limited ...
Matushita Hamilton H Department of Neurosurgery, Division of Pediatric Neurosurgery, University of São Paulo, São Paulo, Brazil, - - 2014
The clinical diagnosis of most common single-suture craniosynostosis is easily set, based on the stereotype of deformities and knowledge of the mechanisms of cranial deformations. However, synostosis of unilateral lambdoid suture, probably due to its lower incidence and similarity with other non-synostotic deformities affecting the posterior portion of the skull, ...
Yanamadala Vijay V Department of Neurosurgery, Massachusetts General Hospital, 55 Fruit Street, White Building Room 502, Boston, MA 02114, USA; Harvard Medical School, Boston, MA, - - 2014
Epidermoid cysts are rare lesions in the pediatric population. The natural history of epidermoids is usually that of slow growth, although rupture and cases of malignant transformation have been reported. Spontaneous regression of an intracranial epidermoid cyst has not previously been described to our knowledge. We present a 3-year-old boy ...
Piccolo Domenico D Department of Dermatology, University of L'Aquila, Via Vetoio-Coppito 2, 67100 L'Aquila, - - 2014
Background Dermoscopy is a very useful and non-invasive technique for in vivo observation and preoperative diagnosis of pigmented skin lesions (PSLs) inasmuch as it enables analysis of surface and subsurface structures that are not discernible to the naked eye. Methods The authors used the ABCD rule of dermoscopy to test ...
Fan Jun J Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of - - 2014
Rathke's cleft cysts (RCCs) are benign cysts typically located in the sellar or suprasellar region; ectopic isolated lesions are extremely rare. The authors describe the case of a 25-year-old man with a giant symptomatic RCC arising primarily at the cerebellopontine angle (CPA), only the second case reported thus far. The ...
Pandey Srikant S Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226 014, - - 2014
Lower gastrointestinal bleeding (LGIB) in infants and children is a difficult diagnostic problem largely due to limitations of small-bowel evaluation. Duplication cysts are rare congenital malformations with variable clinical presentation. This report describes seven children (five boys, two girls and median age 10 [1.5-124] months) with ileal duplication cysts who ...
Litière Saskia S European Organisation for Research and Treatment of Cancer (EORTC), Brussels, Belgium. Electronic address: - - 2014
Progressive disease (PD) per Response Evaluation Criteria in Solid Tumours (RECIST) 1.1 is defined as growth of measurable target lesions, presence of new lesions or unequivocal progression of non-target disease. In this manuscript we explored whether a more refined categorisation of tumour response and/or these components of progression, varying over ...
Zavras Nick - - 2014
An epidermoid cyst in an intrapancreatic accessory spleen is a rare lesion. Despite advances in radiologic techniques, in most cases it has been diagnosed preoperatively as a possible pancreatic neoplasm. Herein, we present a 63-year-old Caucasian woman, diagnosed preoperatively with enhanced-contrast abdominal computed tomography, as having a potential cystic tumor ...
Scarpa Filippo F Department of Veterinary Medical Sciences, University of Bologna, Ozzano Dell'Emilia, - - 2014
A cytological grading for mast cell tumours (MCTs) would be highly desirable, allowing to select the most appropriate therapeutic intervention prior to surgery. This study evaluates the applicability on fine-needle aspirations (FNAs) of the novel Kiupel grading system, based on number of mitoses, multinucleated cells, bizarre nuclei and presence of ...
Lacarbonara Mariano - - 2014
We analyzed the etiopathogenetic, clinical, radiographic, and histopathologic aspects of keratocystic odontogenic tumors, particularly in association with dental anomalies of number, with the aim of providing useful information for their correct diagnosis, treatment, and prognosis within a multidisciplinary approach. A 14-year-old Caucasian girl presented for observation of bilateral agenesis of ...
Miwa Haruo H Gastroenterological Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, Kanagawa, 232-0024, - - 2014
To investigate the usefulness of contrast-enhanced three-dimensional ultrasonography (CE 3D US) for differential diagnosis of solid pancreatic lesions. Eighty-five patients with solid pancreatic lesions who underwent CE 3D US were retrospectively analyzed. Sixty-four patients had pancreatic ductal adenocarcinoma (PDAC), 10 had mass-forming pancreatitis (MFP), and 11 had neuroendocrine tumor (NET). ...
Fukuhara Takahiro T Department of Otolaryngology-Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago 683-8504, - - 2014
Shear wave elastography (SWE) using acoustic radiation force impulse (ARFI) is a novel ultrasonography technique. The aim of this study was to investigate the clinical usefulness of quantitative SWE for differentiating thyroid nodules. For phantom study, we measured the shear wave velocities (SWVs) of the four spheres of 2- and ...
Schroeder Gregory D GD ∞Department of Orthopaedic Surgery, Northwestern University **Department of Orthopaedic Surgery, Cleveland Clinic +Department of Orthopaedic Surgery, NorthShore - - 2014
Study Design. Cohort StudyObjective. To determine the effect of cervical spine pathology on athletes entering the NFL.Background. The association of symptomatic cervical spine pathology with American football athletes has been described, however, it is unknown how pre-existing cervical spine pathology affects career performance of a NFL player.Methods. The medical evaluations ...
de Miguel R R Servicio de Dermatología, Trincay Polyclinic, Cayman Islands. Electronic address: - - 2014
Many dermatologists are largely unfamiliar with arteriovenous malformations (AVMs). This is partly due to the low prevalence of these lesions and to the fact that they are generally managed by other specialists, in particular, interventional radiologists and pediatric, maxillofacial, and plastic surgeons. In this article, we review the recommended nomenclature ...
Raya José M JM Department of Hematopathology, Hospital Universitario de Canarias, Tenerife, - - 2014
The diagnosis of primary myelofibrosis (PMF) strongly relies on the bone marrow biopsy findings, but a report model has not been standardised. Our aim was to establish general recommendations for bone marrow evaluation and standardised reporting in a case suspicious of PMF. The Delphi method was employed to obtain expert ...
Jia Cong-Wei CW Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Primary gastric B-cell non-Hodgkin's lymphoma (B-NHL) has a similar morphocytological presentation to severe chronic gastritis, which complicates the pathological diagnosis of this disease. To investigate the practicality and utility of the BIOMED-2 standardized primer system for the diagnosis of primary gastric B-NHL from endoscopic biopsy specimens, we selected 65 cases ...
Ghigna Maria-Rosa MR Department of Pathology, Marie Lannelongue Surgical Centre, 92350, Le Plessis Robinson, France; INSERM UMR 999, LabEx LERMIT, Marie Lannelongue Surgical Centre, Univ Paris-Sud, School of medicine, Kremlin-Bicêtre, - - 2014
Angiomatoid fibrous histiocytoma (AFH) is a rare neoplastic disease usually occurring in dermis or subcutis of the extremities of young adults or children. Though sporadic cases in deep soft tissue and visceral organs have been reported, this is the first description of AFH developing in a large artery. Paraffin sections ...
Borel Nicole N Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Switzerland. Electronic address: - - 2014
Abortion in ruminants is a major cause of economic loss worldwide, and the management and control of outbreaks is important in limiting their spread, and in preventing zoonotic infections. Given that rapid and accurate laboratory diagnosis is central to controlling abortion outbreaks, the submission of tissue samples to laboratories offering ...
Ustun Berrin B Department of Pathology, Yale University School of Medicine, 310 Cedar Street, CB 510A, New Haven, CT, 06510, - - 2014
Follicular variant of papillary thyroid carcinoma (FVPTC) creates a continuous diagnostic dilemma among pathologists because of the paucity of nuclear changes of papillary carcinoma and overlapping features with benign and other neoplastic follicular lesions. Current guidelines for the management of thyroid nodules recommend surgery for confirmed PTC, suspicious for PTC, ...
Nathan Cherie-Ann O CA Department of Otolaryngology-Head & Neck Surgery, Louisiana State University Health Shreveport, Shreveport, Louisiana, - - 2014
This study aimed to determine the feasibility of using probe-based confocal laser endomicroscopy (pCLE) in the diagnostic differentiation of non-neoplastic lesions from precancerous and cancerous lesions of head and neck patients. Diagnostic test evaluation. Louisiana State University Health Shreveport. Intravenous injection of fluorescein was given to patients with precancerous and ...
Jeyabalan Abiramy A North Bristol Lung Centre, North Bristol NHS Trust, Southmead Hospital, Bristol, - - 2014
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive mediastinal node sampling technique used for lung cancer staging and diagnosis of mediastinal lesions. The four published studies assessing sampling with 21-G or 22-G needles conflict. The study objective is to evaluate the diagnostic utility of 21-G versus 22-G EBUS-TBNA ...
Jamilloux Yvan Y Department of Internal Medicine, Hopital de la Croix-Rousse, Université Claude Bernard Lyon I, Lyon, - - 2014
Uveitis is a frequent (20-50%) and early feature of sarcoidosis. Typical sarcoid uveitis presents with mutton-fat keratic precipitates, iris nodules, and anterior and posterior synechiae. Posterior involvement includes vitreitis, vasculitis, and choroidal lesions. Cystoid macular edema is the most important and sight-threatening consequence. Histologic proof from a biopsy is the ...
Ciudad-Blanco C C Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: - - 2014
Dermoscopy is a complementary technique that has led to major advances in the diagnosis of pigmented skin lesions. The aim of this study was to describe the dermoscopic features of a series of melanomas and analyze the differences between melanomas in situ and invasive melanomas. We retrospectively recorded epidemiological, clinical, ...
Gwak Jng Won JW Department of Radiology, Ansan Hospital, Korea University College of Medicine, 516 Gojan-dong Danwon-gu, Ansan-si, Gyeonggi-do, 425-707, Korea, - - 2014
We present a case of isolated calyx that was mistaken for a large cyst. A 47-year-old woman was referred for sclerotherapy of a large cystic lesion on her left kidney. Computed tomography (CT) and ultrasound showed that the cystic lesion was a large cyst. We noticed that the cystic lesion ...
Sawaya Jennifer L JL University of Nevada School of Medicine, Las Vegas, NV, - - 2014
Poroma is a benign adnexal neoplasm of the terminal sweat gland duct. Although poromas have traditionally been thought to originate from the eccrine sweat gland, there have been cases of apocrine etiology as well. Eccrine and apocrine poromas typically present as erythematous or flesh-colored nodules on the palms and soles. ...
Xavier Samuel Porfirio SP From the *Department of Oral and Maxillofacial Surgery and Periodontics, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo; †Department of Craniomaxillofacial Surgery, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo; and ‡Department of Surgery and Integrated Clinic, Araçatuba Dental School, Universidade Estadual Paulista Júlio de Mesquita Filho-UNESP, Araçatuba, São Paulo, - - 2014
Ameloblastoma is a relatively uncommon benign odontogenic tumor, which is locally aggressive and has a high tendency to recur, despite its benign histopathologic features. This pathology can be classified into 4 groups: unicystic, solid or multicystic, peripheral, and malignant. There are 3 variants of unicystic ameloblastoma, as luminal, intraluminal, and ...
Tarantino Ilaria I Gastroenterology Department, ISMETT/UPMC (Mediterranean Institute for Transplantation and Advanced Specialized Therapies/University of Pittsburgh Medical Center in Italy), Palermo, Italy. Electronic address: - - 2014
Endoscopic ultrasound fine needle aspiration has a central role in the diagnostic algorithm of solid pancreatic masses. Data comparing the fine needle aspiration performed with different aspiration volume and without aspiration are lacking. We compared endoscopic ultrasound fine needle aspiration performed with the 22 gauge needle with different aspiration volumes ...
Hijioka Susumu S From the Departments of *Gastroenterology, and †Gastrointestinal Surgery, Aichi Cancer Center Hospital, Nagoya, Japan; ‡Department of Tropical Medicine and Gastroenterology, Assiut University Hospital, Assiut, Egypt; §Department of Medical Hepatology, Institute of Liver and Biliary Sciences, Delhi, India; and ∥Department of Endoscopy, Aichi Cancer Center Hospital, Nagoya, - - 2014
This study investigated whether a risk assessment nomogram can predict the malignant potential of intraductal papillary mucinous neoplasms (IPMNs) and provide valuable information for the follow-up and counseling strategies of such patients. We studied 126 of 589 patients with IPMN who were followed up for at least 36 months with ...
Wright Gerald Paul GP From the *Grand Rapids Medical Education Partners/Michigan State University General Surgery Residency Program; †Michigan State University College of Human Medicine; ‡Grand River Gastroenterology; §Mercy Health Saint Mary's Hospital; and ∥Spectrum Health Medical Group, Grand Rapids, - - 2014
Reports on the use of endoscopic ultrasound (EUS) in differentiating benign, premalignant, and malignant pancreatic lesions have been widely variable, particularly with cystic neoplasms. We evaluated the use of EUS for cystic pancreatic lesions in a community hospital setting. All patients who underwent EUS for cystic pancreatic neoplasms from 2007 ...
Layfield Lester J LJ Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, - - 2014
The Papanicolaou Society of Cytopathology has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound-guided fine-needle aspiration, terminology and nomenclature of pancreatobiliary disease, ancillary testing, and post-biopsy management. All documents are based on the expertise of the authors, a review of the literature, discussions of the ...
Kurtycz Daniel D Department of Pathology, University of Wisconsin, Wisconsin State Laboratory of Hygiene, Madison, - - 2014
The papanicolaou society of cytopathology (PSC) has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) biopsy, techniques of EUS-FNA, terminology and nomenclature for pancreatobiliary cytology, ancillary testing, and postprocedure management. All documents are based on the expertise of the authors, ...
Crum Todd T MS, Department of Emergency Medicine, University of Arizona Medical Center, PO Box 245057, Tucson, AZ 85724 USA. - - 2014
Objectives- The purpose of this study was to compare sonographically guided vascular access using standard and echo-enhanced needles in a variety of tissue-simulating vascular phantoms. Methods- We conducted a prospective single-blinded observational study at an academic medical center. All participants performed real-time sonographically guided vascular access using both a standard ...
Lu Rong R Department of Ultrasonography, Xiangya Hospital, Central South University, 87 Xiangya Rd, 410008 Changsha, Hunan, China. - - 2014
Objectives- This study aimed to evaluate the clinical value of ultrasound elastography in the differential diagnosis of benign and malignant cervical lesions and to compare the accuracy of the elasticity score and strain ratio in differentiating cervical lesions. Methods- B-mode sonography and ultrasound elastography were performed on 84 cervical lesions ...
Park Sung Hee SH Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjakgu, Seoul 156-755, Korea. - - 2014
Primary thyroid hemangiomas are extremely rare, and only a few cases have been previously reported. Primary hemangiomas are developmental anomalies resulting from the inability of the angioblastic mesenchyme to form canals. Thyroid hemangiomas are generally considered difficult to diagnose preoperatively because of their low incidence and nonspecific imaging findings. Here ...
Zhang Yi-Feng YF Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Tenth People's Hospital of Tongji University, 301 Yanchangzhong Rd, 200072 Shanghai, China. - - 2014
Objectives- Acoustic radiation force impulse elastography is a newly developed ultrasound elasticity imaging technique that included both Virtual Touch tissue quantification and Virtual Touch tissue imaging (VTI; Siemens Medical Solutions, Mountain View, CA). This study aimed to evaluate the usefulness of VTI in differentiating malignant from benign thyroid nodules. Methods- ...
Ghajarzadeh Mahsa M 1 Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, - - 2014
OBJECTIVE. The aim of this systematic review was to determine the diagnostic accuracy of sonoelastography in detecting malignant thyroid nodules. MATERIALS AND METHODS. A systematic search in MEDLINE and bibliographic databases was performed for the terms "thyroid nodule" and "sonoelastography." The inclusion criteria were the report of a 4- or ...
Keplinger Kara M KM Department of Surgery, Wexner Medical Center, The Ohio State University, 395 West 12th Avenue, Room 654, Columbus, OH 43210-1267, - - 2014
Working knowledge of extrahepatic biliary anatomy is of paramount importance to the general surgeon. The embryologic development of the extrahepatic biliary tract is discussed in this article as is the highly variable anatomy of the biliary tract and its associated vasculature. The salient conditions related to the embryology and anatomy ...
Vlašín Michal M International Clinical Research Center (ICRC), St. Anne's University Hospital Brno, Pekařská 53, 656 91 Brno, Czech Republic (Vlašín, Kohout, Hronová); Department of Pharmacology, and Immunotherapy, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic (Lukáč, Kauerová, Mašek, Bartheldyová, Koudelka, Korvasová, Plocková, Turánek); Section of Small Animal Diseases, University of Veterinary and Pharmaceutical Sciences, Palackého 1-3, 612 42 Brno, Czech Republic (Vlašín, Kohout, - - 2014
Specific contrast ultrasound is widely applied in diagnostic procedures on humans but remains underused in veterinary medicine. The objective of this study was to evaluate the use of microbubble-based contrast for rapid ultrasonographic diagnosis of thrombosis in small animals, using male New Zealand white rabbits (average weight about 3.5 kg) ...
Witek Tadeusz D TD *The Commonwealth Medical College †Geisinger-Community Medical Center, Scranton, - - 2014
Benign multicystic peritoneal mesothelioma is a rare cystic tumor with approximately 140 cases reported to date. It is found mainly in women of reproductive age and is commonly attached to the serosal surface of pelvic viscera. The pathogenesis is uncertain and debate regarding its neoplastic or reactive nature exists. The ...
Virmani Jitendra J Department of Electronics and Communication Engineering, Jaypee University of Information Technology, Waknaghat, Solan, 173234 Himachal Pradesh, India, - - 2014
A neural network ensemble (NNE) based computer-aided diagnostic (CAD) system to assist radiologists in differential diagnosis between focal liver lesions (FLLs), including (1) typical and atypical cases of Cyst, hemangioma (HEM) and metastatic carcinoma (MET) lesions, (2) small and large hepatocellular carcinoma (HCC) lesions, along with (3) normal (NOR) liver ...
Kunhimangalam Reeda R National Institute of Technology, NIT Calicut (PO), Kozhikode, Kerala, India, 673601, - - 2014
The prevalence of peripheral neuropathy in general population is ever increasing. The diagnosis and classification of peripheral neuropathies is often difficult as it involves careful clinical and electro-diagnostic examination by an expert neurologist. In developing countries a large percentage of the disease remains undiagnosed due to lack of adequate number ...
Odronic Shelley I SI Robert J Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, - - 2014
Many peripheral lung lesions are beyond the reach of conventional bronchoscopes, and require percutaneous CT-guided or open surgical biopsy, which carry increased risks to the patient. Electromagnetic navigation bronchoscopy (ENB) is a relatively new technique, which uses an image guided localization system to direct steerable bronchoscopic tools to predetermined points ...
Pemmaraju Naresh N Department of Pathology, Baylor University Medical Center at - - 2014
We report a case of a triple-hit lymphoma in a 72-year-old man. This lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymphoma has different prognostic and ...
Talusan Paul G PG Department of Orthopaedics & Rehabilitation, Yale University School of Medicine, New Haven, CT 06519, - - 2014
Osteochondritis dissecans of the talus is a subset of osteochondral lesions of the talus that also includes osteochondral fractures, avascular necrosis, and degenerative arthritis. Osteochondral lesions of the talus can be associated with injury to the ankle. This article discusses the anatomy, pathoanatomy, history, physical examination, imaging, management algorithm, and ...
Jacobs John C JC Jr University of Utah School of Medicine, 30 North 1900 East, Salt Lake City, UT 84132, USA. Electronic address: - - 2014
Multiple systems for classifying osteochondritis dissecans (OCD) of the knee have been reported. These existing classification systems have some similar characteristics, such as stable lesion/intact articular cartilage and presence of a loose body. However, variations are found in the number of stages and specific lesion characteristics assessed. Currently, no system ...
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