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Nayak Satheesha B SB Department of Anatomy, Melaka Manipal Medical College, Manipal University, Manipal, Karnataka, - - 2014
Double gallbladder is one of the rare congenital anomalies of the gallbladder. Failure to detect an accessory gallbladder hampers diagnosis and treatment of cholecystitis, which might result in recurrent attacks of cholecystitis. In addition, presence of peritoneal folds extending from the stomach and duodenum to the gallbladder is very rare. ...
Minuto Michele N MN Department of Surgical Sciences (DISC), University of Genoa, Genoa, - - 2014
We review the progress and state-of-the-art applications of studies in Magnetic Resonance Spectroscopy (MRS) and Imaging as an aid for diagnosis of thyroid lesions of different nature, especially focusing our attention to those lesions that are cytologically undetermined. It appears that the high-resolution of High-Resolution Magic-Angle-Spinning (HRMAS) MRS improves the ...
Leyva Alejandro Molina AM University Hospital, Granada, - - 2014
Granular cell tumour is a rare tumour of neural origin usually located on the face and the neck. The biological behaviour is usually benign. However, certain clinical and histopathological features should alert physicians to a malignant behaviour. This case report describes the occurrence of a granular cell tumour in the ...
Rokito Steven E SE *Division of Sports Medicine, NSLIJ, New Hyde Park, NY †The Ryu Hurvitz Orthopedic Clinic, Santa Barbara, - - 2014
The diagnosis and management of SLAP lesions in the overhead athlete remains a challenge for the sports medicine specialist due to variable anatomy, changes with aging, concomitant pathology, lack of dependable physical findings on examination, and lack of sensitivity and specificity with imaging studies. This article presents a comprehensive review ...
Lemal Richard R CHU Clermont-Ferrand, service d'hématologie clinique adulte et de thérapie cellulaire, 63003 Clermont-Ferrand, France ; Clermont Université, Université d'Auvergne, EA7283, CIC501, BP 10448, 63000 Clermont-Ferrand, - - 2014
Haematological malignancies comprise a wide spectrum of well-defined entities, and require a risk-adapted treatment. Beside the classical diagnostic tools, haematologists have routinely access to more and more biological markers, which provide different informations about diagnosis, prognosis and targetable status of each individual disease and permit to define a personalized risk-adapted ...
Mazzaglia Peter J PJ Department of General Surgery, The Warren Alpert School of Medicine, Brown University, 593 Eddy Street, APC 4, Providence, RI 02905, USA. Electronic address: - - 2014
Incidental adrenal neoplasms are usually nonfunctioning benign adenomas. Once hormonal production has been assessed, the nonsecreting lesions must be evaluated for the possibility of malignancy. This evaluation relies primarily on the radiographic characteristics. This article focuses on the current state of radiologic technology available to accurately assess nonfunctioning adrenal incidentalomas. ...
Kamińska-Winciorek Grażyna G The Center for Diagnostics and Treatment of Skin Diseases, Katowice, Poland. Head of Center: Grażyna Kamińska-Winciorek MD, - - 2014
Halo nevus (HN) is a rare dermatologic entity characterized by a typical whitish rim encircling the existing melanocytic nevus resembling a halo. The clinical picture is suggesting its diagnosis, but so far only several dermoscopic descriptions of halo nevus have existed in the PubMed database. To present the clinical and ...
Kayaçetin Serra S Department of Pathology, Ankara Numune Education and Training Hospital, Ankara, Turkey. - - 2014
Stomach endoscopic biopsies are made to determine the diagnosis of the illness, its stage, and follow-up after the treatment. It is very significant to collaborate with the clinician while evaluating endoscopic biopsies. Besides the clinical and laboratory information of the patient, the endoscopic appearance of the lesion should be known. ...
Khalil Danny N DN Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, - - 2014
Historically the approach to treating noncutaneous melanoma was largely guided by the experience with cutaneous melanoma, particularly in the metastatic setting. However, as genetic tools have allowed clinicians to better characterize these malignancies, their unique biology has become apparent. The ability to accurately distinguish the subtypes of melanoma and the ...
Zhu Jian-Wei - - 2014
Lymphangioma is a benign proliferation of the lymphatic vessels that accounts for approximately 4% of vascular malformations and 26% of benign vascular tumors. Compared to those arising in nongenital areas, lymphangiomas of the vulva and genital areas are more hyperplastic, possibly due to the loose connective tissue, which can cause ...
Bermeo-Escalona J-R JR Universidad Autónoma del Estado de México, CIEAO, Facultad de Odontología, Jesús Carranza 100, Colonia Universidad, Toluca, Estado de México, C.P. 50130, México, - - 2014
Objective: To evaluate the effectiveness of Toki's criteria in identifying the HPV L1 protein in oral lesions with the use of immunohistochemistry (IHC) and to determine which criteria optimize such identification. Study Design: Retrospective study of 277 cases diagnosed as HPV lesions at 22 years. Tests of sensitivity, specificity, positive ...
Harvey Adrian M AM Section of General Surgery and Surgical Oncology, Department of Surgery, Faculty of Medicine, Foothills Medical Center, University of Calgary, 1403 29th Street Northwest, FMC, North Tower, Calgary, Alberta T2N 2T9, Canada. Electronic address: - - 2014
Primary hyperaldosteronism is an important and commonly unrecognized secondary cause of hypertension. This article provides an overview of the current literature with respect to screening, diagnosis, and lateralization. Selection and outcomes of medical and surgical treatment are discussed.
Cortés-Ramírez D-A DA Unidad de Medicina Bucal y de Patología Oral y Maxilofacial, Dpto. de Estomatología II, Universidad del País Vasco /EHU, Leioa 48940. Bizkaia. España (Spain), - - 2014
The oral lichenoid disease (OLD) includes different chronic inflammatory processes such as oral lichen planus (OLP) and oral lichenoid lesions (OLL), both entities with controversial diagnosis and malignant potential. Epidermal growth factor receptor (EFGR) is an important oral carcinogenesis biomarker and overexpressed in several oral potentially malignant disorders. Objectives: To ...
Streicher Jenna L JL Department of Dermatology, Indiana University School of Medicine, 550 N University Blvd, Ste 3240, Indianapolis, IN 46202, USA. - - 2014
Patients with α₁-antitrypsin (AAT) deficiency may develop cutaneous manifestations of the disorder that histologically appear as panniculitis. Algorithms consistently emphasize measuring AAT levels when both clinical and histological features of deficiency are present; however, the patient's medical history and a physical examination alone can be extremely helpful in guiding the ...
Gordon H H Gastroenterology, Hampshire Hospitals Foundation Trust, Winchester, - - 2014
Endoscopic ultrasound (EUS) guided sampling of advanced malignant pancreatic lesions is increasingly being performed in order to confirm malignancy prior to chemotherapy and or treatment. Meta-analysis of 33 studies examining solid lesion EUS FNA tissue acquisition in 4984 patients showed a pooled sensitivity of 85%, increasing to 91% if suspicious ...
Tse Lap Ah Shelly LA JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, - - 2014
To evaluate whether the presence of pleural abnormalities was a reasonable marker to predict mesothelioma among workers with asbestosis in Hong Kong. This is a historical cohort study comprised of 99 male asbestosis workers registered in the Pneumoconiosis Clinic under Hospital Authority of the Hong Kong Government during 1981-2008 who ...
Sehgal V V Gastroenterology, University College London Hospital (UCLH), London, - - 2014
Barrett's oesophagus (BE) is the pre-cursor for oesophageal adenocarcinoma. Endoscopic surveillance is performed to detect dysplasia in BE as it is likely to be amenable to curative treatment. Current surveillance relies on white-light endoscopy to obtain 4-quadrant biopsies through every 2cm of the BE segment. This samples less than 5% ...
Lamoth Frédéric F Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Box 102359, Durham, NC 27710, USA; Clinical Microbiology Laboratory, Department of Pathology, Duke University Medical Center, 108 Carl building, Durham, NC 27710, USA; Infectious Diseases Service and Institute of Microbiology, Lausanne University Hospital, Rue du Bugnon 46, 1011 Lausanne, Switzerland. Electronic address: - - 2014
Diagnosis of invasive fungal pneumonias by conventional culture methods is difficult to assess and often delayed. Nonmolecular fungal markers have emerged as an important adjunctive tool to support their diagnosis in combination with other clinical, radiologic, and microbiological criteria of invasive fungal diseases. Concerns about the sensitivity and specificity of ...
Cottin Vincent V Hospices Civils de Lyon, Hôpital Louis Pradel, Service de pneumologie - Centre de référence national des maladies pulmonaires rares, Lyon, France. Université de Lyon, Université Claude Bernard Lyon 1, INRA, UMR754 IFR 128, Lyon, FranceHospices Civils de Lyon, Hôpital Louis Pradel, Service de pneumologie - Centre de référence national des maladies pulmonaires rares, Lyon, France. Université de Lyon, Université Claude Bernard Lyon 1, INRA, UMR754 IFR 128, Lyon, France - - 2014
This review presents the results of the 2013 Advancing IPF Research (AIR) survey, which assessed current approaches to the diagnosis and treatment of idiopathic pulmonary fibrosis (IPF) by experienced physicians. A total of 149 physicians, predominantly from European countries, replied to the 28-question survey. The results of the AIR survey ...
Jadhav Aniket B AB Department of Oral and Maxillofacial Radiology, University of Connecticut School of Dental Medicine, Farmington, CT, - - 2014
An osteolytic lesion with a small central area of mineralization and sclerotic borders was discovered incidentally in the clivus on the cone-beam computed tomography (CBCT) of a 27-year-old male patient. This benign appearance indicated a primary differential diagnosis of non-aggressive lesions such as fibro-osseous lesions and arrested pneumatization. Further, on ...
Hebeda K K Department of Pathology, Radboudumc, Nijmegen, The - - 2014
Although immunophenotyping (IPT) using flow cytometry is a routine technique that is applied in many laboratories as a diagnostic tool for lymphadenopathy, some diagnostic challenges persist. In this review, we will discuss pitfalls in the daily practice of lymph node diagnostics with the focus on general characteristics as lymphoid scatter ...
Zhang Mingbo M Department of Ultrasound, General Hospital of Chinese PLA, Beijing, - - 2014
The purpose of this study was to build a logistic regression formula for ameliorating the diagnosis of subcentimeter thyroid nodules. The sonographic features of 889 subcentimeter nodules were reviewed retrospectively with reference of histologic results. The diagnostic performance of each feature was evaluated. Multivariate binary logistic regression was used to ...
Chan Jason Y K JY Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, - - 2014
Transoral robotic surgery (TORS) offers a minimally invasive approach to the pharynx with a magnified 3-dimensional view, wristed instruments with 7 degrees of freedom, and tremor filtration. TORS affords an excellent approach to benign lesions of the pharynx. This article is grouped into subsites of the nasopharynx, oropharynx, and hypopharynx, ...
Lesan S S Dept. of Oral Medicine Dentistry, Islamic Azad University of Medical Sciences, Tehran, - - 2014
The increasing use of smokeless tobacco in the last 15 years has motivated researchers to evaluate its impact on its user's health. The aim of this study was to determine the frequency of oral lesions related to smokeless tobacco and any possible correlation between the frequency of oral lesions and ...
Sandu Irina I Clinical Rehabilitation Hospital Radiology Department "Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. - - 2014
Ultrasonography, with its various techniques (grey-scale, color Doppler, sonoelastography) offers many signs for the differentiation between benign and malignant neck lymph nodes. In spite of recent progress, the US appearance may be misleading. We present three cases in which the ultrasonographic appearance of the lymph nodes was misleading as compared ...
Y Ghosh G Assistant Professor, Department of Surgery, Punjab Institute of Medical Sciences , Jalandhar, India - - 2014
Torsion of greater omentum is one of the rare causes of acute abdominal pain. It can be primary or secondary. Primary Omental Torsion (POT) occurs because a mobile, thicken segment of omentum rotates around a proximal fixed point in the absence of any associated or secondary intra-abdominal pathology. Secondary omental ...
Yamakado Koichiro K Department of Interventional Radiology, Mie University School of Medicine, Mie, - - 2014
Although laparoscopic adrenalectomy has remained the standard of care for the treatment for adrenal tumors, percutaneous image-guided ablation therapy, such as chemical ablation, radiofrequency ablation, cryoablation, and microwave ablation, has been shown to be clinically useful in many nonsurgical candidates. Ablation therapy has been used to treat both functioning adenomas ...
Andresen V V Israelitisches Krankenhaus, Hamburg, - - 2014
The confident diagnosis of chronic abdominal conditions can be challenging. This study assessed the diagnostic process in irritable bowel syndrome with constipation (IBS‑C), irritable bowel syndrome with diarrhoea (IBS‑D), inflammatory bowel disease (IBD) and chronic constipation (CC). Online interviews were conducted with 25 experts, 100 gastroenterologists (GEs) and 104 general ...
Valeyre Dominique D Pneumology Department, Avicenne Universitary Hospital, Bobigny, - - 2014
Sarcoidosis is a systemic disease of unknown cause characterized by the formation of immune granulomas which most often involve the lung and the lymphatic system. Sarcoidosis may encompass numerous different clinical presentations. Typical presentations often prompt a rapid diagnosis while in 25 to 50% of cases, diverse and less typical ...
Ameer Faisal F FRACP, Senior Advanced Trainee Registrar, Thoracic Medicine, Royal Adelaide Hospital, and Clinical Associate Lecturer, Discipline of Medicine, University of Adelaide, - - 2014
Polymyalgia rheumatica is a relatively common inflammatory rheumatic disease. There are no validated international guidelines available for the diagnosis and treatment of PMR; however, diagnostic and classification criteria are currently being developed. The aim of this article is to summarise the main management options suggested by American College of Rheumatology ...
Choi Jae Woo JW Department of Dermatology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, - - 2014
Computer-aided image analysis (CAIA) has been suggested as an effective diagnostic tool for pigmented skin lesions (PSLs), especially melanoma. However, few studies on benign PSLs have been reported. The purpose of this study was to evaluate benign PSLs with our CAIA software and analyze the differences between the parameters of ...
Mizuno Shoma S Department of Respiratory Internal Medicine, Himeji St. Mary's Hospital, Himeji, Hyogo 670-0801, - - 2014
Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for those previously exposed to asbestos. He had been smoking since ...
Donnelly Mc M Gastroenterology, NHS Grampian, Aberdeen, - - 2014
At least 1% of hospitalised patients will have a pancreatic cystic lesion on cross sectional imaging (1). Differentiation of benign and potentially malignant/malignant pancreatic cystic lesions using conventional radiology and prior to surgery is difficult. Endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) is considered safe, yet there is relatively ...
Gomez J - - 2014
To assess the impact of patient risk status on Colombian dentists' caries related treatment decisions for early to intermediate caries lesions (ICDAS code 2 to 4). A web-based questionnaire assessed dentists' views on the management of early/intermediate lesions. The questionnaire included questions on demographic characteristics, five clinical scenarios with randomised ...
Liu Shangang S Department of Radiation Oncology, Shandong Cancer Hospital and Institute, School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Science, 440 Jiyan Road, Jinan, 250117, Shandong Province, China, - - 2014
The purpose of our study was to evaluate the diagnostic accuracy of MRI-guided percutaneous transthoracic needle biopsy (PTNB) of solitary pulmonary nodules (SPNs). Retrospective review of 69 patients who underwent MR-guided PTNB of SPNs was performed. Each case was reviewed for complications. The final diagnosis was established by surgical pathology ...
Kudo Taiki T Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, - - 2014
EUS-guided FNA (EUS-FNA) has a high diagnostic accuracy for pancreatic diseases. However, although most reports have typically focused on cytology, histological tissue quality has rarely been investigated. The effectiveness of EUS-FNA combined with high negative pressure (HNP) suction was recently indicated for tissue acquisition, but has not thus far been ...
Yamagishi Tomoko - - 2014
Non-small cell lung cancers (NSCLCs) are frequently heterogeneous and in approximately 70% of cases, NSCLCs are diagnosed and staged by small biopsies or cytology rather than by examination of surgically resected specimens. Thus, in most patients, the diagnosis is established based on examination of preoperative specimens alone. Recently, classification of ...
Gunjan Deepak D Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, - - 2014
The small intestine is an uncommon site of gastro-intestinal (GI) bleeding; however it is the commonest cause of obscure GI bleeding. It may require multiple blood transfusions, diagnostic procedures and repeated hospitalizations. Angiodysplasia is the commonest cause of obscure GI bleeding, particularly in the elderly. Inflammatory lesions and tumours are ...
Lo Muzio L L Department of Clinical and Experimental Medicine, University of Foggia, Foggia, - - 2014
Cervico-facial actinomycosis is an infectious, suppurative, and granulomatous disease due to Actinomyces species. Usually, the diagnosis is confirmed by microbiological cultures; however, the need for careful anaerobic handling of specimens often makes it difficult to obtain an effective microbial growth. Therefore, we conducted a retrospective study on biopsy samples from ...
Chugh Reema R Cardiology Division, CMOB 308, Kaiser Permanente Medical Center, Panorama City, - - 2014
Patent ductus arteriosus (PDA) represents at least 5-10% of all congenital heart defects (CHDs) making it a very important commonly diagnosed lesion. Although spontaneous closure of the PDA occurs within 24 to 48 hours after birth in the majority, those children who do not have natural or surgical closure may have ...
Seppala Nicholas N The Ottawa Hospital, General Campus, 501 Smyth Road, Ottawa, ON, K1S 8L6, Canada, - - 2014
To evaluate inter-observer agreement of MRI features and classification of cystic renal masses among radiologist and radiology trainees. Four readers (two radiologists and two radiology trainees) retrospectively reviewed 100 cystic renal lesions on gadolinium enhanced MRI and assigned each a Bosniak classification (1, 2, 2F, 3, and 4). Lesions were ...
Pellacani G G Department of Dermatology, University of Modena and Reggio Emilia, - - 2014
Dermatoscopy increases both sensitivity and specificity for melanoma diagnosis. Reflectance confocal microscopy (RCM) is a non invasive technique which complements dermatoscopy, in the evaluation of equivocal lesions at cellular resolution. The purpose of the study was to prospectively determine the potential impact of confocal microscopy when implemented in a routine ...
Moriarty B B Kings College Hospital, Department of Dermatology, Denmark Hill, SE5 9RS, London, United - - 2014
HS is a chronic suppurative skin condition characterized by recurrent inflammatory nodules, cysts, abscesses and sinus tracts in apocrine gland-bearing sites. The clinical presentation is highly variable both in terms of the cutaneous features, distribution, presence of complications (e.g. fistula formation, lymphoedema) extra-cutaneous features (arthritis, interstitial keratitis(1) ) and associated ...
Muramoto Osamu - - 2014
The aim of this essay is to elaborate philosophical and ethical underpinnings of posthumous diagnosis of famous historical figures based on literary and artistic products, or commonly called retrospective diagnosis. It discusses ontological and epistemic challenges raised in the humanities and social sciences, and attempts to systematically reply to their ...
Gerhard Rene R Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, - - 2014
Second-opinion diagnosis (SOD) on pathological material is an accepted practice before definitive therapy is considered for referred patients. The thyroid gland is an anatomical site prone to diagnostic disagreement between pathologists. We performed a review of the literature that addressed the role of interinstitutional SOD on thyroid fine-needle aspirations (FNAs). ...
Minot Douglas M DM Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, - - 2014
Transthoracic fine needle aspiration (TFNA)/core needle biopsy (CNB) under computed tomography (CT) guidance has proved useful in the assessment of pulmonary nodules. We sought to determine the TFNA false-negative (FN) rate at our institution and identify potential causes of FN diagnoses. Medical records were reviewed from 1,043 consecutive patients who ...
Floridi Chiara C Interventional Radiology, University of Insubria, Varese, Italy, - - 2014
The aim of this study was to evaluate the feasibility of percutaneous transthoracic needle biopsy of pulmonary nodules under cone-beam computed tomography (CBCT) with "XperGuide" navigation guidance. From February 2010 to January 2012, 100 patients (63 men and 37 women; mean age 67.27 years; range 21-88 years) with 100 lung nodules (44 ≤ 3 cm, ...
Krull Adam C AC Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, - - 2014
Bovine Digital Dermatitis (DD) is a leading cause of lameness in dairy cattle throughout the world. Despite 35 years of research, the definitive etiologic agent associated with the disease process is still unknown. Previous studies have demonstrated that multiple bacterial species are associated with lesions, with spirochetes being the most ...
Roberts Ian S D IS Department of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, - - 2014
IgA nephropathy is defined by the presence of IgA-dominant or co-dominant immune deposits within glomeruli. Biopsy specimens meeting these diagnostic criteria have a range of histological changes that are reflected in the variable clinical course of IgA nephropathy. The impact of histology on outcomes in IgA nephropathy has been clarified ...
Quentin Michael M Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, Moorenstr. 5, D-40225, Dusseldorf, Germany. Electronic address: - - 2014
MRI-guided biopsies are increasingly used for prostate cancer (PCa) diagnosis. However, there is a lack of well controlled prospective trials to support this treatment method. The aim of this study was to prospectively compare the MRI-guided in-bore biopsy with the standard systematic TRUS-guided biopsy in biopsy naïve men with elevated ...
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