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Giordano Thomas J TJ Department of Pathology, University of Michigan Health System, Ann Arbor, MI - - 2014
Molecular testing for oncogenic gene alterations provides clinically actionable information essential for the optimal management of follicular cell thyroid cancer. We aimed to establish the distribution and frequency of common oncogenic gene mutations and chromosomal rearrangements in a comprehensive set of benign and malignant thyroid lesions. A case-control study was ...
Jia Cong-Wei CW Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Primary gastric B-cell non-Hodgkin's lymphoma (B-NHL) has a similar morphocytological presentation to severe chronic gastritis, which complicates the pathological diagnosis of this disease. To investigate the practicality and utility of the BIOMED-2 standardized primer system for the diagnosis of primary gastric B-NHL from endoscopic biopsy specimens, we selected 65 cases ...
Borel Nicole N Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Switzerland. Electronic address: - - 2014
Abortion in ruminants is a major cause of economic loss worldwide, and the management and control of outbreaks is important in limiting their spread, and in preventing zoonotic infections. Given that rapid and accurate laboratory diagnosis is central to controlling abortion outbreaks, the submission of tissue samples to laboratories offering ...
Ghigna Maria-Rosa MR Department of Pathology, Marie Lannelongue Surgical Centre, 92350, Le Plessis Robinson, France; INSERM UMR 999, LabEx LERMIT, Marie Lannelongue Surgical Centre, Univ Paris-Sud, School of medicine, Kremlin-Bicêtre, - - 2014
Angiomatoid fibrous histiocytoma (AFH) is a rare neoplastic disease usually occurring in dermis or subcutis of the extremities of young adults or children. Though sporadic cases in deep soft tissue and visceral organs have been reported, this is the first description of AFH developing in a large artery. Paraffin sections ...
Ustun Berrin B Department of Pathology, Yale University School of Medicine, 310 Cedar Street, CB 510A, New Haven, CT, 06510, - - 2014
Follicular variant of papillary thyroid carcinoma (FVPTC) creates a continuous diagnostic dilemma among pathologists because of the paucity of nuclear changes of papillary carcinoma and overlapping features with benign and other neoplastic follicular lesions. Current guidelines for the management of thyroid nodules recommend surgery for confirmed PTC, suspicious for PTC, ...
Nathan Cherie-Ann O CA Department of Otolaryngology-Head & Neck Surgery, Louisiana State University Health Shreveport, Shreveport, Louisiana, - - 2014
This study aimed to determine the feasibility of using probe-based confocal laser endomicroscopy (pCLE) in the diagnostic differentiation of non-neoplastic lesions from precancerous and cancerous lesions of head and neck patients. Diagnostic test evaluation. Louisiana State University Health Shreveport. Intravenous injection of fluorescein was given to patients with precancerous and ...
Ciudad-Blanco C C Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: - - 2014
Dermoscopy is a complementary technique that has led to major advances in the diagnosis of pigmented skin lesions. The aim of this study was to describe the dermoscopic features of a series of melanomas and analyze the differences between melanomas in situ and invasive melanomas. We retrospectively recorded epidemiological, clinical, ...
Jeyabalan Abiramy A North Bristol Lung Centre, North Bristol NHS Trust, Southmead Hospital, Bristol, - - 2014
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive mediastinal node sampling technique used for lung cancer staging and diagnosis of mediastinal lesions. The four published studies assessing sampling with 21-G or 22-G needles conflict. The study objective is to evaluate the diagnostic utility of 21-G versus 22-G EBUS-TBNA ...
Jamilloux Yvan Y Department of Internal Medicine, Hopital de la Croix-Rousse, Université Claude Bernard Lyon I, Lyon, - - 2014
Uveitis is a frequent (20-50%) and early feature of sarcoidosis. Typical sarcoid uveitis presents with mutton-fat keratic precipitates, iris nodules, and anterior and posterior synechiae. Posterior involvement includes vitreitis, vasculitis, and choroidal lesions. Cystoid macular edema is the most important and sight-threatening consequence. Histologic proof from a biopsy is the ...
Tarantino Ilaria I Gastroenterology Department, ISMETT/UPMC (Mediterranean Institute for Transplantation and Advanced Specialized Therapies/University of Pittsburgh Medical Center in Italy), Palermo, Italy. Electronic address: - - 2014
Endoscopic ultrasound fine needle aspiration has a central role in the diagnostic algorithm of solid pancreatic masses. Data comparing the fine needle aspiration performed with different aspiration volume and without aspiration are lacking. We compared endoscopic ultrasound fine needle aspiration performed with the 22 gauge needle with different aspiration volumes ...
Xavier Samuel Porfirio SP From the *Department of Oral and Maxillofacial Surgery and Periodontics, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo; †Department of Craniomaxillofacial Surgery, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo; and ‡Department of Surgery and Integrated Clinic, Araçatuba Dental School, Universidade Estadual Paulista Júlio de Mesquita Filho-UNESP, Araçatuba, São Paulo, - - 2014
Ameloblastoma is a relatively uncommon benign odontogenic tumor, which is locally aggressive and has a high tendency to recur, despite its benign histopathologic features. This pathology can be classified into 4 groups: unicystic, solid or multicystic, peripheral, and malignant. There are 3 variants of unicystic ameloblastoma, as luminal, intraluminal, and ...
Gwak Jng Won JW Department of Radiology, Ansan Hospital, Korea University College of Medicine, 516 Gojan-dong Danwon-gu, Ansan-si, Gyeonggi-do, 425-707, Korea, - - 2014
We present a case of isolated calyx that was mistaken for a large cyst. A 47-year-old woman was referred for sclerotherapy of a large cystic lesion on her left kidney. Computed tomography (CT) and ultrasound showed that the cystic lesion was a large cyst. We noticed that the cystic lesion ...
Sawaya Jennifer L JL University of Nevada School of Medicine, Las Vegas, NV, - - 2014
Poroma is a benign adnexal neoplasm of the terminal sweat gland duct. Although poromas have traditionally been thought to originate from the eccrine sweat gland, there have been cases of apocrine etiology as well. Eccrine and apocrine poromas typically present as erythematous or flesh-colored nodules on the palms and soles. ...
Banihashemi Amir A Pathology Department, Faculty of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran. Electronic address: - - 2014
This study was performed on a series of prostate needle biopsies with diagnosis of atypical small acinar proliferation (ASAP) to verify to what extent the application of immunohistochemistry (IHC) for p504s and p63 markers as well as expert consultation by still images could affect the diagnosis. The results of these ...
Imada Thaís Sumie Nozu TS Department of Stomatology, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, - - 2014
In the absence of syndromes, bilateral dentigerous cysts (DC) located on the jaws are unusual. In English based language literature review, we only found eight reports of nonsyndromic bilateral dentigerous cyst associated with mandibular third molars. Therefore, we report the unusual occurrence of sizable nonsyndromic bilateral DC associated with mandibular ...
Srikanth S S Department of Pathology, Prathima Institute of Medical Science, Andhra Pradesh, - - 2014
The present study was undertaken to compare the fine-needle aspiration cytology (FNAC) and the fine-needle non-aspiration cytology (FNNAC) techniques in head and neck swellings and to study the cytology features of various head and neck swellings. A total of 138 cases of head and neck swellings were sampled by a ...
Bomm Lislaine L Instituto Nacional do Câncer, Rio de Janeiro, RJ, - - 2014
Skin cancer is the most common neoplasm in Brazil. Melanoma accounts for 4% of these neoplasms. Although childhood melanoma is rare, there is evidence that its incidence is increasing, placing it among the most important public health problems for the future. This work sought to conduct a retrospective review of ...
Tamai Naoto N Department of Endoscopy, The Jikei University School of Medicine, Tokyo, - - 2014
We previously reported the effectiveness of color tone intensity analysis using autofluorescence imaging (AFI) for distinguishing between colorectal neoplastic and non-neoplastic lesions. Moreover, a second-generation AFI system has become commercially available in Japan. In the present study, we assessed the effectiveness of color tone intensity analysis using a second-generation AFI ...
Kasat Vikrant O VO Department of Oral Medicine and Radiology, Rural Dental College, Loni, - - 2014
Malignant fibrous histiocytoma (MFH) is the most common soft-tissue sarcoma occurring in adults. This entity was first described by O'Brian and Stout in 1964. Apart from the soft-tissues, this tumor has been reported to occur in all other parts of the body including bone. It has male predilection and is ...
Pemmaraju Naresh N Department of Pathology, Baylor University Medical Center at - - 2014
We report a case of a triple-hit lymphoma in a 72-year-old man. This lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymphoma has different prognostic and ...
Chiu Han-Mo HM Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Colonoscopy Quality Assurance Working Group, The Digestive Endoscopy, Society of Taiwan, Taipei, - - 2014
The majority of polyps detected during colonoscopy are diminutive polyps, for which the cost of pathological analysis is substantial. In our analysis of a screening cohort of 10 737 subjects undergoing screening colonoscopy, a total of 15 877 neoplastic lesions were detected, of which 10 816 (68.1%) were diminutive lesions. Of those diminutive ...
Hocke Michael M Klinikum Meiningen GmbH, Bergstrasse 3, D-98617 Meiningen, - - 2014
Cystic pancreatic lesions are a growing diagnostic challenge. The aim of this study was to proof a new diagnostic concept based on contrast-enhanced endoscopic ultrasound (CE-EUS) for differential diagnosis. A total of 125 patients with unclear cystic pancreatic lesions were included. The initial diagnostic was made by CE-EUS dividing the ...
Li Hui H Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, - - 2014
To review current knowledge of the Morel-Lavallee lesion (MLL) to help clinicians become familiar with this entity. Familiarization may decrease missed diagnoses and misdiagnoses. It could also help steer the clinician to the proper treatment choice. A search was performed via PubMed and EMBASE from 1966 to July 2013 using ...
Ghajarzadeh Mahsa M 1 Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, - - 2014
OBJECTIVE. The aim of this systematic review was to determine the diagnostic accuracy of sonoelastography in detecting malignant thyroid nodules. MATERIALS AND METHODS. A systematic search in MEDLINE and bibliographic databases was performed for the terms "thyroid nodule" and "sonoelastography." The inclusion criteria were the report of a 4- or ...
Pittayanon Rapat R Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, - - 2014
Currently, the strategy for real-time endoscopic diagnosis of duodenal, including ampullary, adenoma is still unclear. In the era of high-definition and magnification endoscopy, using this modality for the detection and diagnosis of these neoplasms is very challenging for endoscopists. Over the past 10 years, many instruments have been developed to ...
Takeuchi Yoji Y Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, - - 2014
A 'resect and discard' strategy using non-magnifying narrow band imaging (N-NBI) has been proposed for reducing screening colonoscopy costs, but it does not take into consideration advanced histology and magnifying NBI (M-NBI) that can potentially further improve the 'resect and discard' strategy. We conducted a pilot study to investigate the ...
Minca Eugen C EC *Departments of Molecular Pathology, Cytopathology, and Anatomic Pathology, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland, Ohio; †Departments of Translational Hematology and Oncology Research, and Solid Tumor Oncology, Taussig Cancer Institute, Cleveland, Ohio; and ‡Respiratory Institute, Cleveland Clinic Foundation, Cleveland, - - 2014
Oncogenic anaplastic lymphoma kinase (ALK) gene rearrangements in non-small-cell lung carcinomas (NSCLC) provide the basis for targeted therapy with crizotinib and other specific ALK inhibitors. Treatment eligibility is conventionally determined by the Food and Drug Administration-approved companion diagnostic fluorescence in situ hybridization (FISH) assay on paraffin-embedded tissue (PET). On limited ...
Iglesias-Garcia Julio J Gastroenterology Department, Foundation for Research in Digestive Diseases (FIENAD), University Hospital of Santiago de Compostela, - - 2014
Endoscopic ultrasound (EUS) has evolved to become a crucial tool for the evaluation of pancreatic diseases, among them solid pancreatic lesions. However, its ability to determine whether a lesion is malignant or not is difficult to establish based only in the endosonographic image. EUS-guided fine needle aspiration (EUS-FNA) allows obtaining ...
Santos Bruno Simão Dos BS Fluminense Federal University, Niterói, RJ, - - 2014
We describe a case of melanoma with the presence of comedo-like openings at dermoscopy. These structures, typical of seborrheic keratosis, represent an uncommon finding in melanoma. We emphasize the importance of searching for specific dermoscopic criteria for melanocytic lesions during the examination of a pigmented lesion, despite possible observations of ...
Lu Rong R Department of Ultrasonography, Xiangya Hospital, Central South University, 87 Xiangya Rd, 410008 Changsha, Hunan, China. - - 2014
Objectives- This study aimed to evaluate the clinical value of ultrasound elastography in the differential diagnosis of benign and malignant cervical lesions and to compare the accuracy of the elasticity score and strain ratio in differentiating cervical lesions. Methods- B-mode sonography and ultrasound elastography were performed on 84 cervical lesions ...
Hijioka Susumu S From the Departments of *Gastroenterology, and †Gastrointestinal Surgery, Aichi Cancer Center Hospital, Nagoya, Japan; ‡Department of Tropical Medicine and Gastroenterology, Assiut University Hospital, Assiut, Egypt; §Department of Medical Hepatology, Institute of Liver and Biliary Sciences, Delhi, India; and ∥Department of Endoscopy, Aichi Cancer Center Hospital, Nagoya, - - 2014
This study investigated whether a risk assessment nomogram can predict the malignant potential of intraductal papillary mucinous neoplasms (IPMNs) and provide valuable information for the follow-up and counseling strategies of such patients. We studied 126 of 589 patients with IPMN who were followed up for at least 36 months with ...
Kikuchi Daisuke D Department of Gastroenterology, Toranomon Hospital, Tokyo, - - 2014
A novel diagnostic algorithm for magnifying endoscopy with narrow band imaging (ME-NBI) for superficial non-ampullary duodenal epithelial tumors (SNADET) is needed because of diagnostic difficulties. In the present study, ME-NBI images taken prior to endoscopic treatment were retrospectively analyzed to investigate the relationship between ME-NBI findings and pathological findings. Lesions ...
Manchanda Adesh S - - 2014
Calcifying odontogenic cyst (COC) shows extreme diversity in its clinical and histopathological features, as well as in its biological behavior. Because of this diversity, there has been confusion and disagreement on the terminology and classification of this lesion. Attempts to classify COC can be divided into two concepts: monistic and ...
Virmani Jitendra J Department of Electronics and Communication Engineering, Jaypee University of Information Technology, Waknaghat, Solan, 173234 Himachal Pradesh, India, - - 2014
A neural network ensemble (NNE) based computer-aided diagnostic (CAD) system to assist radiologists in differential diagnosis between focal liver lesions (FLLs), including (1) typical and atypical cases of Cyst, hemangioma (HEM) and metastatic carcinoma (MET) lesions, (2) small and large hepatocellular carcinoma (HCC) lesions, along with (3) normal (NOR) liver ...
Layfield Lester J LJ Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, - - 2014
The Papanicolaou Society of Cytopathology has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound-guided fine-needle aspiration, terminology and nomenclature of pancreatobiliary disease, ancillary testing, and post-biopsy management. All documents are based on the expertise of the authors, a review of the literature, discussions of the ...
Talusan Paul G PG Department of Orthopaedics & Rehabilitation, Yale University School of Medicine, New Haven, CT 06519, - - 2014
Osteochondritis dissecans of the talus is a subset of osteochondral lesions of the talus that also includes osteochondral fractures, avascular necrosis, and degenerative arthritis. Osteochondral lesions of the talus can be associated with injury to the ankle. This article discusses the anatomy, pathoanatomy, history, physical examination, imaging, management algorithm, and ...
Keplinger Kara M KM Department of Surgery, Wexner Medical Center, The Ohio State University, 395 West 12th Avenue, Room 654, Columbus, OH 43210-1267, - - 2014
Working knowledge of extrahepatic biliary anatomy is of paramount importance to the general surgeon. The embryologic development of the extrahepatic biliary tract is discussed in this article as is the highly variable anatomy of the biliary tract and its associated vasculature. The salient conditions related to the embryology and anatomy ...
Gupta Swati S Department of Oral Medicine and Radiology, Subharti Dental College, Subhartipuram, Meerut, - - 2014
Background: Oral cancer accounts for 5% of all malignant tumors and 60% of these lesions are well advanced at the time of diagnosis. The early diagnosis could prevent a large number of deaths due to this disease. Aims: This study aims to evaluate and compare the clinical usefulness of exfoliative ...
Kunhimangalam Reeda R National Institute of Technology, NIT Calicut (PO), Kozhikode, Kerala, India, 673601, - - 2014
The prevalence of peripheral neuropathy in general population is ever increasing. The diagnosis and classification of peripheral neuropathies is often difficult as it involves careful clinical and electro-diagnostic examination by an expert neurologist. In developing countries a large percentage of the disease remains undiagnosed due to lack of adequate number ...
De Angelis C C Department of Gastroenterology and Hepatology Endoscopy and Endosonography Center Molinette Hospital, University of Turin, Turin, Italy - eusdeang@hotmail.com or - - 2014
Endoscopic ultrasound (EUS) is a technique that combines the potential of endoscopy, which enables the visual examination of the mucosal surface of any gastrointestinal (GI) tract, with ultrasonography. Despite diagnostic and therapeutic advance, pancreatic cancer (PC), in particular ductal adenocarcinoma, remains the most deadly of all GI malignancies, with a ...
Touchinsky Susan S 1Driving Rehabilitation by Genesis Rehab Services, Kennett Square , Pennsylvania , - - 2014
ABSTRACT This paper describes the development and use of information sheets for occupational therapy practitioners to use as guides for evaluation and intervention planning to address their client's driving and community mobility needs. Called Driving Pathways by Diagnosis Sheets, the information assists therapists with direction to connect impairment to driving ...
Mehta Asmita A AA Department of Pulmonary Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, - - 2014
To determine the diagnostic utility of adenosine deaminase (ADA) in exudative pleural effusions of different etiologies. It was an observational study conducted at a tertiary care teaching institute. Of a total of 171 pleural fluid samples, 122 were found to be exudates and were included in the study. Pleural fluid ...
Park Ji Hye JH Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) uses six diagnostic categories to standardize communication of thyroid fine-needle aspiration (FNA) interpretations between clinicians and cytopathologists. Since several studies have questioned the diagnostic accuracy of this system, we examined its accuracy in our hospital. We calculated the incidences and malignancy rates ...
Crum Todd T MS, Department of Emergency Medicine, University of Arizona Medical Center, PO Box 245057, Tucson, AZ 85724 USA. - - 2014
Objectives- The purpose of this study was to compare sonographically guided vascular access using standard and echo-enhanced needles in a variety of tissue-simulating vascular phantoms. Methods- We conducted a prospective single-blinded observational study at an academic medical center. All participants performed real-time sonographically guided vascular access using both a standard ...
Angelini Fábio Janson FJ Department of Orthopaedics and Traumatology, Institute of Orthopedics and Traumatology-Hospital and Clinics, Faculty of Medicine, University of São Paulo, São Paulo, - - 2014
Injury to the posterolateral corner (PLC) is difficult to diagnose; most lesions of this type are included within the context of complex knee injuries. Study of the posterolateral complex is growing in importance because of the complex instability generated by these injuries. Although various physical examination tests are described for ...
Rosendahl Cliff C School of Medicine, The University of Queensland, - - 2014
The incidence of nodular melanoma (NM) has been consistently described as at least 10-15% of total melanomas for over 15 years despite advances in diagnostic algorithms and medical technology. NMs are strongly correlated with faster rates of growth and poorer prognosis and thus provide clinicians with a challenge for early ...
Kurtycz Daniel D Department of Pathology, University of Wisconsin, Wisconsin State Laboratory of Hygiene, Madison, - - 2014
The papanicolaou society of cytopathology (PSC) has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) biopsy, techniques of EUS-FNA, terminology and nomenclature for pancreatobiliary cytology, ancillary testing, and postprocedure management. All documents are based on the expertise of the authors, ...
Zhang Yi-Feng YF Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Tenth People's Hospital of Tongji University, 301 Yanchangzhong Rd, 200072 Shanghai, China. - - 2014
Objectives- Acoustic radiation force impulse elastography is a newly developed ultrasound elasticity imaging technique that included both Virtual Touch tissue quantification and Virtual Touch tissue imaging (VTI; Siemens Medical Solutions, Mountain View, CA). This study aimed to evaluate the usefulness of VTI in differentiating malignant from benign thyroid nodules. Methods- ...
Park Sung Hee SH Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjakgu, Seoul 156-755, Korea. - - 2014
Primary thyroid hemangiomas are extremely rare, and only a few cases have been previously reported. Primary hemangiomas are developmental anomalies resulting from the inability of the angioblastic mesenchyme to form canals. Thyroid hemangiomas are generally considered difficult to diagnose preoperatively because of their low incidence and nonspecific imaging findings. Here ...
Bokhari Rakan Farouk RF King Abdul Aziz University Hospital, Jeddah, Kingdom of Saudi - - 2014
Lipomatous extra-axial lesions in the Sylvian fissure are a rare entity. Their identification, however, is usually simple if a systematic radiological approach is adopted. The best line of management for these lesions is still a matter of controversy and fraught with complications. We present a case of a Sylvian fissure ...
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