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Mancini Nicasio N Laboratory of Microbiology and Virology, University Vita-Salute San Raffaele, Via Olgettina 58, 20132, Milan, Italy, - - 2015
The need of rapid and sensitive diagnostic techniques for sepsis is every day more compelling. Its morbidity and mortality loads are dramatically high, with one quarter of patients eventually dying. Several diagnostic progresses have been made in the last years using both molecular- and nonmolecular-based approaches, and they have to ...
Krishnamohan Prashanth P Department of Neurology, University of Kentucky College of Medicine, 740 S. Limestone St., Lexington, KY, 40536-0284, - - 2014
Spinal epidural abscess (SEA) remains a relatively infrequent diagnosis. Staphylococcus aureus is the most common organism identified, and the infectious source in SEA emanates from skin and soft tissue infections in about 20 % of instances. The thoracic spine is most often involved followed by the lumbar spine. The classic triad ...
Gong Zhaohua Z Department of Oncology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong 264000, P.R. - - 2014
Primary penile lymphoma presenting with priapism as the initial symptom is extremely rare. In total, <10 cases have been previously reported. The diagnosis can be difficult and patients often develop metastasis. The current study reports the case of a 48-year-old male, who presented with a one-month history of painless priapism. ...
Xing Dejun D Department of Medical Oncology, Jilin Cancer Hospital, Changchun, Jilin 130012, P.R. - - 2014
A benign lymphoepithelial lesion (BLEL) is an idiopathic inflammation of the parotid gland, characterized by hyperplasia, lymphocyte infiltration and the formation of epimyoepithelial islands, as well as atrophy of the gland parenchyma. Common treatment methods include immunosuppression and glucocorticoid therapies, in addition to surgical dissections. Cytokine-induced killer (CIK) cells sensitized ...
Johannesma Paul Christiaan PC Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The - - 2014
The development and natural course of lung cysts in patients with Birt-Hogg-Dubé syndrome (BHD) is still unclear, and the relationship between lung cysts and pneumothorax is not fully clarified. Based on the follow-up results of thoracic imaging in six patients with BHD, we hypothesize that decreased potential for stretching of ...
Licci Stefano S From Department of Pathology, "Santo Spirito" Hospital, Rome, Italy; - - 2014
Lymphangiomas are relatively uncommon lesions of the lymphatic channels that can arise in virtually any part of the body provided by lymphatic vessels. The most common localization is the head/neck region, with only sporadic reports in other sites. The mediastinum is a rare location, with around 20 cases reported in ...
Putra Juan J Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United - - 2014
A 59-year-old man with T-cell prolymphocytic leukemia on alemtuzumab presented with neutropenic fever, intermittent nausea, and multiple ill-defined low attenuation foci in the liver on abdominal computed tomography scan which were suspicious for metastatic disease. Histological examination revealed the diagnosis of adenovirus hepatitis. Patient responded well to cidofovir. Adenovirus hepatitis ...
Ruiz-Morales Jose M JM Oncology center. Medica Sur Hospital. Mexico City, - - 2014
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and is the fifth most common cancer in the world; its incidence has been increasing in recent years. Extrahepatic spread is present at the time of diagnosis in only about 5 to 15% of patients. Skeletal metastasis of ...
Koga Monji M Department of Dermatology, Faculty of Medicine, Fukuoka University, Fukuoka, - - 2014
Epidermolysis bullosa (EB) is a group of inherited rare diseases characterized by fragility and blistering of the skin and mucous membranes. An EB nevus (EBN) is a very rare acquired nevus that occurs only in patients with EB. An EBN usually arises in an area of previous blistering, and frequently ...
Yao Jianhua J NIH, Radiology and Imaging Sciences, Bethesda, Maryland, United - - 2014
Rationale. Sirolimus therapy stabilizes lung function and reduces the size of chylous effusions and lymphangioleiomyomas in patients with lymphangioleiomyomatosis. Objectives. To determine whether sirolimus has beneficial effects on lung function, cystic areas and adjacent lung parenchyma, whether these effects are sustained, and sirolimus is well tolerated by patients. Methods. Lung ...
de Oliveira Renata Schlesner RS Department of Pediatric Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil; Faculdade da Serra Gaúcha, Caxias do Sul, Rio Grande do Sul, - - 2014
To evaluate the effectiveness of a treatment for non-cavitated occlusal lesions on erupting permanent molars and to verify whether initial eruption stage and final biofilm accumulation are associated with lesions activity after the treatment. Forty-eight patients aged from 5 to 13 years old were selected. Molars with active non-cavitated lesions on ...
Jiang Jue J Department of Ultrasound, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, 710004, - - 2014
To investigate the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant nodules. One hundred eighty-nine patients with 213 thyroid nodules were enrolled in this retrospective study. All patients underwent preoperative CEUS and were subsequently scheduled for surgery. The pathology results were obtained after surgery. The time-intensity ...
Wei Chenggang C Department of Radiology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510180, Guangdong Province, People's Republic of - - 2014
We aim to investigate the diagnostic capability of diffusion-weighted imaging using parallel acquisition technique for the differentiation between hepatic metastases and benign focal lesions with a meta-analysis. The meta-analysis included a total of 858 hepatic metastases and 440 benign liver lesions from nine studies. The pooled sensitivity and specificity of ...
Eidlitz-Markus Tal T Pediatric Headache Clinic, Department of Ambulatory Day Care Hospitalization, Schneider Children's Medical Center of Israel, Petach Tikva; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Arachnoid cysts are generally identified incidentally on brain imaging, although they occasionally cause symptoms because of expansion or bleeding. This study aims to describe patients in whom an arachnoid cyst was identified on magnetic resonance imaging (MRI) study performed for the evaluation of headache in a pediatric headache clinic and ...
Hilal Talal T Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, USA - - 2014
A 36-year-old male who carried a diagnosis of irritable bowel syndrome presented with chronic watery diarrhea and was found to have hepatomegaly on physical exam. A computed tomography (CT) scan of the abdomen revealed hepatomegaly with lesions suspicious for metastatic disease. A colonoscopy revealed a polypoid lesion in the terminal ...
De Giorgi Vincenzo V aDepartment of Dermatology, University of Florence, Florence bDivision of Epidemiology and Biostatistics, European Institute of Oncology, Milan, - - 2014
To assess the patient's capability of performing a correct skin-check examination we investigated the association of melanoma detection pattern with Breslow thickness, by melanoma body area. In this prospective observational study, patients with primary cutaneous melanoma who presented at the Department of Dermatology at the University of Florence between January ...
Menis D D Department of Dermatology, Hospital Doce de Octubre, Madrid, - - 2014
The first patient is a 65-year old woman with a pigmented plantar lesion appearing 1 year before and gradually spreading. Physical examination revealed a black pigmented patch of 4x2.3 cm, with light brown elements in the ball of the left foot. The dermoscopy showed a parallel ridge pattern (PRP) associated ...
Song Joo Y JY *Laboratory of Pathology ‡Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD †Department of Pathology and Laboratory Medicine, City of Hope Medical Center, Duarte, CA §Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, - - 2014
Lymphomatoid granulomatosis (LYG) is a rare angiocentric and angiodestructive Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder. It is hypothesized that these patients have dysregulated immune surveillance of EBV. We reviewed the biopsies of 55 patients with LYG who were referred for a prospective trial at the National Cancer Institute (1995 to ...
Atasoy Mehmet Mahir MM Department of Radiology, Maltepe University School of Medicine, Istanbul, Turkey. - - 2014
The aim of this study was to evaluate the 10-gauge vacuum-assisted stereotactic biopsy (VASB) of isolated Breast Imaging Reporting and Data System (BI-RADS) 4 microcalcifications, using histology and follow-up results. From January 2011 to June 2013, VASB was performed on 132 lesions, and 66 microcalcification-only lesions of BI-RADS 4 were ...
Agozzino Marina M San Gallicano Dermatological Institute - IRCCS, Rome, - - 2014
Background: Plaque psoriasis (PP) and seborrheic dermatitis (SD) are chronic inflammatory skin diseases with similar clinical and pathological features. Differential diagnosis can be difficult, especially when particular skin areas of the face are involved. Reflectance confocal microscopy (RCM) has been demonstrated to be useful for 'real-time' diagnosis of skin inflammatory ...
Casparis S S Department of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, Plattenstrasse 15, 8032, Zurich, Switzerland, - - 2014
This 10-year retrospective study analyzed the incidence of malignant transformation of oral lichen planus (OLP). The study also included dysplasia and oral lichenoid lesion (OLL) in the initial biopsy as a potential differential diagnosis. A total of 692 scalpel biopsies were taken from 542 patients (207 [38.2 %] men and 335 ...
Doshi Ankur M AM Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, New York, NY, 10016, USA, - - 2014
To determine multi-parametric MRI features that can help differentiate malignant omental caking from benign omental thickening in the setting of portal hypertension. We identified 19 patients with an abnormal omentum on MRI and an available reference standard: 11 patients with portal hypertension and benign omental thickening (9 male, 2 female, ...
Schröder Julian J From the Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany (J.S., B. Cheng, C.G., G.T.); Centrum für Schlaganfallforschung Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany (M.E., J.B.F.); Klinik für Neurologie, Universität Erlangen-Nürnberg, Erlangen, Germany (M.K.); Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston (O.W.); Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (D.-W.K.); Department of Neurology, University of California, Los Angeles (D.S.L.); Université de Bordeaux, CHU de Bordeaux, Service de NeuroImagerie Diagnostique de Thérapeutique, Bordeaux, France (T.T.); Klinik für Neurologie, Universitätsklinikum Frankfurt, Frankfurt, Germany (O.C.S.); Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (S.C., B. Campbell); National Institute of Neurological Disorders and Stroke, Bethesda, MD (M.L.); Department of Neurology and Neurotherapeutics, Seton/UT Southwestern Clinical Research Institute of Austin, UT Southwestern Medical Center, Austin, TX (S.W.); and Klinik und Poliklinik für Neuroradiologische Diagnostik und Intervention, Unversitätsklinikum Hamburg-Eppendorf, Hamburg, Germany (J.F.). - - 2014
Alberta Stroke Program Early Computed Tomographic Score (ASPECTS) has been used to estimate diffusion-weighted imaging (DWI) lesion volume in acute stroke. We aimed to assess correlations of DWI-ASPECTS with lesion volume in different middle cerebral artery (MCA) subregions and reproduce existing ASPECTS thresholds of a malignant profile defined by lesion ...
Tuzun D D Ankara Atatürk Research and Training Hospital, Department of Endocrinology and Metabolism - - - 2014
This study evaluated the effectiveness of elastosonography (ES) scoring and strain index (SI) in diagnosing patients with thyroid nodules composed primarily of Hurthle cells. This study retrospectively analyzed 57 patients with thyroid nodules composed predominantly of Hurthle cells on fine needle aspiration cytology (FNAC). Patients were evaluated by thyroid ultrasonography ...
Patel Mikin V MV Department of Radiology, University of Chicago Hospitals, Chicago, - - 2014
The purpose of this study was to investigate the impact of lesion proximity to the diaphragm on computed tomography (CT)-guided percutaneous biopsy yield and pneumothorax rates. An Institutional Review Board-approved retrospective review of all CT-guided percutaneous core lung biopsies at a single institution performed between August 1, 2011 and July ...
Fernandes Violet M VM Center for Cancer and Blood Disorders, Children's National Health System, Washington, District of Columbia; Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, District of - - 2014
Kaposiform lymphangiomatosis (KLA) is a rare proliferation of abnormal lymphatic vessels often complicated by pleural/pericardial effusions and a consumptive coagulopathy that may lead to life threatening hemorrhage. Establishing the diagnosis is challenging due to the clinical heterogeneity and variable findings in laboratory values, radiographic features, and pathologic characteristics. We report ...
Ceylan Savas S Neurosurgery Department, Medical Faculty, Pituitary Research Centre, Kocaeli University, Umuttepe Yerleşkesi Eski, İstanbul Yolu 10. Km, 41380 Umuttepe, İzmit, Kocaeli, Turkey, - - 2014
An extended endoscopic transsphenoidal approach is required for skull base lesions extending to the suprasellar area. Inferior approach using the infrachiasmatic corridor allows access to the lesions through the tumor growth that is favorable for the extended transsphenoidal approaches. Infrachiasmatic corridor is a safer route for the inferior approaches that ...
Ricucci Domenico D Private practice, Cetraro, Italy. Electronic address: - - 2014
Clinicians routinely face conditions in which they have to decide whether the dental pulp can be saved or not. This study evaluated how reliable the clinical diagnosis of normal pulp/reversible pulpitis (savable pulp) or irreversible pulpitis (nonsavable pulp) is when compared with the histologic diagnosis. The study material consisted of ...
M Clin Dent Fahim Vohra FV Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi - - 2014
The aim was to systematically review the efficacy of photodynamic therapy (PDT) in the management of oral premalignant lesions. The addressed focused question was "Is PDT effective in the management of oral premalignant lesions?" PubMed/Medline, Google-Scholar, EMBASE and ISI Web of Knowledge databases were searched from 1984 till June 2014 ...
Furlan Fabricio C FC Department of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, - - 2014
Background: Hypopigmented mycosis fungoides (HMF) is a rare subtype of mycosis fungoides (MF). We compared patients with exclusive hypopigmented lesions with a group of MF patients with concomitant different lesions. Methods: 20 patients with HMF only and 14 patients with hypopigmented lesions concomitant with other types of lesions (mixed MF, ...
Beddis H P HP Department of Restorative Dentistry, Leeds Dental Institute, Clarendon Way, Leeds, LS2 - - 2014
Trismus is a restriction in the ability to open the mouth. Trismus can occur following trauma, surgery, radiation therapy, infection, inflammatory diseases, temporomandibular disorders (TMD) or less commonly as a result of malignancy. Following two cases of delayed diagnosis of carcinoma presenting with features of TMD to a specialist clinic, ...
Inoue Ritsurou R Department of Pathology, Faculty of Medicine, Fukuoka University; Department of Neurosurgery, Fukuoka University Chikushi Hospital Chikushino, Japan. Electronic address: - - 2014
No predictor of postoperative ischemic events has been identified in patients undergoing carotid artery stenting (CAS). We aimed to determine whether N(ε)-(carboxymethyl)lysine (CML) in debris trapped by an embolic protection filter device is a predictor of postoperative ischemic events. We enrolled 27 patients (73.4 ± 7.2 years; 22 male, 5 female) who underwent ...
Tannemaat Martijn R MR Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, the Netherlands. - - 2014
Psychogenic pseudosyncope (PPS) is common cause of apparent transient loss of consciousness with a dramatic impact on the quality of life. This review aims to give an overview of the definition, incidence, aetiology, diagnosis, treatment and prognosis of PPS based on a combination of literature data and personal experience. The ...
Algra Selma O SO Department of Pediatric Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The - - 2014
To determine whether prenatal diagnosis lowers the risk of preoperative brain injury by assessing differences in the incidence of preoperative brain injury across centers. From 2 prospective cohorts of newborns with complex congenital heart disease studied by preoperative cerebral magnetic resonance imaging, one cohort from the University Medical Center Utrecht ...
Lott Jason P JP Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; Section of Dermatology, Veterans Administration Connecticut Healthcare System, West Haven, - - 2014
Spitz nevi and Spitzoid malignant melanomas are uncommon and may be difficult to distinguish histopathologically. Identification of clinical features associated with these lesions may aid in diagnosis. We sought to identify clinical characteristics associated with Spitz nevi and Spitzoid malignant melanomas. We conducted a retrospective cohort study of Spitz nevi ...
Fibla Juan J JJ Division of General Thoracic Surgery, Mayo Clinic, Rochester, Estados Unidos. Electronic address: - - 2014
Our objective was to evaluate whether the number and volume of surgical lung biopsies (SLB) influence the diagnosis of diffuse interstitial lung disease (ILD). Retrospective study of SLB for suspected ILD in patients from the Mayo Clinic from January 2002 to January 2010. Data were collected in the institution and ...
Raherinantenaina F F Service de chirurgie générale et vasculaire, centre hospitalo-universitaire Joseph Ravoahangy Andrianavalona (CHUJRA), BP 4150, Antananarivo, - - 2014
Non-parasitic liver cysts are rare in our country. We report the second case in a 61-year-old woman admitted for a painful epigastric mass. The diagnosis was suggested by ultrasound and confirmed by histological examination of the surgical specimen. Surgical treatment was performed through a right transverse subcostal incision and consisted ...
Harrington Lacey L Department of Pathology, University of South Florida Morsani College of Medicine, Tampa, - - 2014
Primary cutaneous γδ T-cell lymphoma is an extremely rare and aggressive variant of cutaneous lymphoma. Central nervous system (CNS) involvement, a rare finding, and hemophagocytic syndrome are two complications that are commonly fatal. We describe a 58-year-old patient presenting with skin plaque that subsequently developed subcutaneous nodules diagnosed as cutaneous ...
Al Kadah Basel B Department of Otorhinolaryngology, University Medical Center, Kirrberger Street, 66421, Homburg/Saar, Germany, - - 2014
Correct diagnosis of cervical lymphadenopathy is often a great challenge. The objective of this case study is to describe the distribution of the most common causes of unclear neck swellings presented in an ENT-Department and to evaluate the clinical history, examination and laboratory findings. In a retrospective study at the ...
Cuttler Nirupa N *Departments of Ophthalmology and †Pathology, Beaumont Health System, Royal Oak, MI; and ‡Oakland University William Beaumont School of Medicine, Rochester, - - 2014
To report the clinicopathological correlation of extramedullary hematopoiesis (EMH) of the conjunctiva in a patient with a history of myelofibrosis. Case report. Elevated pink conjunctival lesions developed bilaterally in a 73-year-old man who had been treated for myelofibrosis for 13 years. EMH was detected in the examination of tissue from ...
Carubbi F F Department of Biotechnological and Applied Clinical Sciences, Rheumatology Unit, University of L'Aquila, L'Aquila, Italy - - 2014
The objective of this report is to investigate the prognostic value of minor salivary glands (MSG) assessment, routinely performed with hematoxilin-eosin (H&E) staining, for the diagnosis of primary Sjögren's syndrome (pSS). We retrospectively evaluated clinical, serological and histological features of 794 pSS patients. H&E-stained sections were assessed using the Chisholm ...
Chen Bihong T BT Department of Diagnostic Radiology, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, - - 2014
Objective: Ultrasound-guided core needle biopsy (UG-CNB) is a procedure that is often performed either after repeated inadequate or non-diagnostic ultrasound-guided fine needle aspiration (UG-FNA), or in combination with UG-FNA, in the evaluation of thyroid nodules. The purpose of this study is to compare efficacy and safety of UG-CNB and UG-FNA ...
Siqueira C S CS Department of Oral Pathology, School of Dentistry, Universidade Federal de Uberlândia, Minas Gerais, Brazil; Department of Stomatology, School of Dentistry, Universidade de São Paulo, São Paulo, Brazil. Electronic address: - - 2014
Awareness of the increased prevalence of syphilis is essential for early diagnosis and treatment, and to prevent the spread of the disease. Although serological studies are the primary tool used to confirm the diagnosis of secondary syphilis, biopsy of unsuspected oral lesions is not uncommon in the routine oral pathology ...
Marek M M Department of Neurology, Bonn University Medical Center, Sigmund-Freud-Str. 25, 53105, Bonn, Germany, - - 2014
Focal lesions of brainstem, thalamus, and subcortical white matter may cause movement disorders that are clinically indistinguishable from cerebellar symptoms. It is suspected that ataxia in these cases is due to damage of efferent or afferent pathways of the cerebellum. However, the precise anatomical correlate often remains undefined. We used ...
Kato Yuichiro Y Division of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan, - - 2014
The international consensus guidelines for the management of intraductal papillary mucinous neoplasm (IPMN) of the pancreas were revised in 2012 Tanaka (Pancreatology 12(3):183-197, 2012), making the indications for operation less aggressive. Therefore, the number of branch duct-type IPMN (BD-IPMN) patients requiring follow-up care is expected to increase in the future. ...
Ummarino A A Etromapmacs Pole, Biomedical Sciences School, Lesina (FG), Italy - - - 2014
Esophagogastroduodenoscopy (EGDS) cannot identify microscopic lesions. We determined the contribution of real---time gastric juice analysis in detecting lesions non---detectable with the simple endoscopic inspection. Endoscopy, histology and gastric juice analysis were performed in 216 patients. We assessed six diagnostic strategies: EGDS (strategy---1), EGDS with antral biopsies (hematoxylin---eosin staining) in hypochlorhydrics ...
Elias Martha K MK Division of Allergic Diseases, Mayo Clinic, Rochester, MN, - - 2014
Smaller studies have suggested seasonal variation of the diagnosis of eosinophilic esophagitis with more patients being diagnosed in the aeroallergen season. We evaluated a large group of adult patients for a seasonal variation of the diagnosis of symptomatic eosinophilic esophageal infiltration. We performed a retrospective review of adult patients from ...
DelVecchio Sally P SP Pulmonary/Critical Care Service, Womack Army Medical Center, Fort Bragg, - - 2014
Abstract Objectives: Environmental exposures during military deployments to Iraq and Afghanistan may lead to higher rates of respiratory complaints and diagnoses. This study investigates whether there is a relationship between rates of asthma diagnosis and severity associated with military deployment. Methods: Retrospective review of active duty Army personnel who underwent ...
Ma Shirley P SP Department of Neurosurgery, The University of Melbourne, The Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3052, Australia. Electronic address: - - 2014
Gangliogliomas are rare primary central nervous system tumours that characteristically contain both neuronal and glial neoplastic components. They usually present as solitary, slow growing tumours that are frequently associated with pharmacologically refractory epilepsy. Multicentric variants of the tumour are exceedingly rare. We report a 20-year-old patient with multiple gangliogliomas located ...
Cooper Trenton T Department of Orthopedics, Nationwide Children's Hospital, Columbus, - - 2014
Juvenile osteochondritis dissecans (JOCD) of the knee affects cartilage and subchondral bone surface. Multifocal JOCD is described as multiple lesions within the knee or presence of lesions in other joints. The true prevalence of bilaterality of JOCD is unknown. The purpose of this study is to determine the prevalence of ...
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