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Gammon Bryan B Departments of *Pathology, and †Dermatology, Stanford University, Stanford, - - 2014
: Cutaneous small vessel vasculitis (CSVV) is a nonspecific finding with an extensive differential diagnosis. It is critically important to distinguish skin-limited presentations of CSVV from severe life-threatening systemic vasculitides presenting with CSVV as an initial manifestation. It can be challenging to determine which patients presenting with CSVV are at ...
Xing Wu W Department of Ultrasound in Medicine (W.X., Y.T., F.L., H.B.) and Digestive Endoscopic Center (C.Y., Y.X.), Shanghai Jiaotong University Affiliated Sixth Hospital, Shanghai, - - 2014
The purpose of this study was to evaluate the clinical value of catheter-based miniprobe sonography for diagnosis of esophageal submucosal lesions. A total of 199 patients with esophageal submucosal lesions underwent miniprobe sonography via gastroscopy. The sonograms were reviewed, and the sonographic findings were compared with pathologic findings from specimens ...
Park Jun Ho JH Department of Radiology, Busan Paik Hospital, Inje University School of Medicine, Busan, - - 2014
The aim of this study was to assess the diagnostic accuracy of individual sonographic features and sonographic diagnosis for patients with a clinical suspicion of tuberculous lymphadenitis in the neck. From January 2010 to December 2011, 79 patients who underwent neck sonography and sonographically guided fine-needle aspiration with tuberculosis polymerase ...
Panteli Michalis - - 2014
Malignant transformation as a result of chronic osteomyelitis represents a relatively rare and late complication with a declining incidence in the modern world. For most patients, the interval between the occurrence of the original bacterial infection and the transformation to malignant degeneration is several years. The diagnosis of malignant transformation ...
Zhang Qing Q Department of Urology, The Affiliated Nanjing Drum Tower Hospital, Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, - - 2014
To report the features of contrast-enhanced ultrasonography (CEUS) and computer tomography (CECT) of mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney. Six cases of MTSCC of the kidney were studied, and the literature was reviewed. Ultrasonography, CEUS, and CECT examinations were routinely performed before the operation. Histological analysis, ...
Boon Andrea J AJ From the Departments of Physical Medicine and Rehabilitation (A.J.B., J.A.S., S.G.) and Neurology (A.J.B., J.A.S., J.C.W., E.J.S.), and Divisions of Pain Medicine (Dr. Watson) and Pulmonary and Critical Care Medicine (H.S.), Mayo Clinic, Rochester, MN. C.J.H. is a student, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN. - - 2014
To determine the sensitivity and specificity of B-mode ultrasound in the diagnosis of neuromuscular diaphragmatic dysfunction, including phrenic neuropathy. A prospective study of patients with dyspnea referred to the EMG laboratory over a 2-year time frame for evaluation of neuromuscular respiratory failure who were recruited consecutively and examined with ultrasound ...
Cakal Erman E Ankara Diskapi Training and Research - - 2014
Despite the publication of a recent meta-analysis of elastography in thyroid nodules, further work is necessary on this issue in different populations. In this study, we aimed to evaluate the clinical value of elastography on nodular goiters in mild iodine-deficient regions without excluding patients according to nodule characteristics. This prospective ...
Abbas M M Institute of Pathology, Hannover medical School (MHH), Carl-Neuberg-Str. 1, 30625, Hannover, Germany, - - 2014
Routinely processed skin biopsies are still the mainstay for the diagnosis of melanocytic skin neoplasms (MSNs) and are considered the "gold standard" for individual patient management and clinical trials. The diagnostic challenge of melanocytic lesions of the skin prompts histopathologists to consider new diagnostic tools; among these, immunohistochemistry. We aimed ...
Régnier-Rosencher E E Department of dermatology, Cochin hospital, AP-HP, université René-Descartes Paris V, Paris, France. Electronic address: - - 2014
We report an imported case of Histoplasma capsulatum var. duboisii (H. duboisii) infection in a white French woman revealed by cutaneous lesions of the scalp, 18years after her last stay in West and Central Africa. Asymptomatic bilateral pulmonary infiltrates were discovered on thoracic computed tomography. Skin biopsy allowed the positive diagnosis showing ...
Reynolds Matthew R MR Department of Neurological Surgery, Washington University in St. Louis , St. Louis, MO , - - 2014
Isolated intracranial Rosai-Dorfman Disease is rare. Here, we describe a patient who developed an asymptomatic, right parietal RDD lesion over 18 months while being followed radiographically for another brain lesion. To our knowledge, rapid, de novo radiographic formation of isolated intracranial RDD has never been reported in an asymptomatic patient.
Silav Gökalp G Faculty of Medicine Department of Neurosurgery, Medipol University, İstanbul, Turkey, - - 2014
The optimal surgical treatment for symptomatic middle fossa arachnoid cyst is still controversial. The most leading therapeutic options include cyst shunting and fenestration (endoscopic, microsurgical). We present our experience on surgical treatments of arachnoid cysts. A retrospective data review of 16 children who underwent keyhole craniotomy for microsurgical fenestration and ...
Righi Stefano S From the Division of Otolaryngology, Maxillofacial Surgery and Dentistry, Aosta Hospital, Aosta, - - 2014
Thornwaldt cysts are rare and benign congenital cysts in the region of the pharyngeal bursa, formed by a communication between the notochord and the nasopharyngeal endoderm. They result from a mechanical obstruction, inflammation, or abscess of the pharyngeal bursa. They are superficial to the superior constrictor muscle and covered by ...
De Salvo Gabriella G Medical Retina Department, Moorfields Eye Hospital National Health Service Foundation Trust, London, United Kingdom; National Institute of Health Research Biomedical Research Centre at Moorfields Eye Hospital National Health System Foundation Trust and University College London Institute of Ophthalmology, London, United Kingdom. Electronic address: - - 2014
To evaluate the efficacy of spectral-domain optical coherence tomography (SD-OCT) compared to indocyanine green angiography (ICGA) in detecting idiopathic polypoidal choroidal vasculopathy (PCV) and in differentiating between PCV and occult choroidal neovascularization (CNV). Retrospective observational case control study. SD-OCTs of 51 eyes of 44 consecutive patients who presented with one ...
Pan Zhenyu - - 2014
Primary central nervous system (CNS) melanoma is a type of rare and aggressive tumor that can easily spread to the leptomeninges, and in fact, leptomeningeal metastasis is one of the most serious complications in patients with this carcinoma. Prognosis is extremely poor if a CNS melanoma has metastasized, and there ...
Wong Gentle G Department of Otolaryngology, Head and Neck Surgery, Northwick Park Hospital, Watford Road, HA1 3UJ, - - 2014
The Thy3a cytological group carries a considerable malignancy potential. Our audit demonstrates 50% of resected Thy3a lesions were found to be malignant on histopathological examination. This reduces to 33.9% if we adopt "best case scenario" and assume all Thy3a left unresected are benign. We do not have sufficient evidence to ...
Peric Barbara - - 2014
Carotid paragangliomas are usually slowly enlarging and painless lateral neck masses. These mostly benign lesions are recognized due to their typical location, vessel displacement and specific blood supply, features that are usually seen on different imaging modalities. Surgery for carotid paraganglioma can be associated with immediate cerebrovascular complications or delayed ...
Beume Lena-Alexandra LA Department of Neurology, University Hospital Freiburg, Breisacherstrasse 64, 79106 Freiburg, Germany. Electronic address: - - 2014
We present a 46-year-old woman with a relapse of multiple sclerosis (MS) that began 3months after withdrawal from long-term treatment with natalizumab. Shortly after restart of a single dose of natalizumab she developed a fulminant MS rebound with stupor and tetraparesis. Cerebral MRI showed massive progression in the number of ...
Buy Xavier X Department of radiology, Institut Bergonie, Bordeaux, - - 2014
Pseudomeningoceles are most commonly the result of dural tear during spine surgery. They may sometimes slowly enlarge but they generally develop inside the spinal canal, towards the foramina, or towards the surgical incision. To describe a late and exceptional complication of a surgical discectomy. Case report. We report a unique ...
Okanishi Tohru T Department of Child Neurology, Seirei-Hamamatsu General Hospital, Japan; Department of Pediatrics, Nagoya City University Graduate School of Medicine, Japan. Electronic address: - - 2014
To determine the early changes and evolutions of brain diffusion-weighted imaging (DWI), and analyze prognostic factors of the early changes among patients with neonatal herpes simplex encephalitis (NHSE). We selected patients who developed encephalitis by 28d after birth; had herpes simplex infection; and who underwent magnetic resonance imaging, including DWI, ...
Yoon Ra Gyoung RG Asan Medical Center, Department of Radiology and the Research Institute of Radiology, Seoul, Seoul, Korea, Republic of ; - - 2014
Background: Although fine-needle aspiration (FNA) is a safe and accurate diagnostic procedure for assessing thyroid nodules, it has limitations in diagnosing follicular neoplasms due to its relatively high false-positive rate. The purpose of the present study was to evaluate the diagnostic role of core-needle biopsy (CNB) for thyroid nodules with ...
Brown M T MT Royal National Orthopaedic Hospital, London Bone and Soft Tissue Sarcoma Service, Brockley Hill, Stanmore, Middlesex, HA7 4LP, - - 2014
The pre-operative differentiation between enchondroma, low-grade chondrosarcoma and high-grade chondrosarcoma remains a diagnostic challenge. We reviewed the accuracy and safety of the radiological grading of cartilaginous tumours through the assessment of, first, pre-operative radiological and post-operative histological agreement, and second the rate of recurrence in lesions confirmed as high-grade on ...
Chiaravalloti Anthony J AJ SUNY Upstate Medical University, Syracuse, New - - 2014
Previous studies have shown that dermatologists detect thinner melanomas than both non-dermatologists and patients in high incidence areas. The authors report depths of melanomas in a central New York practice where the incidence is low, hypothesizing that incidental melanomas detected by a dermatologist will be thinner than melanomas that are ...
Løhmann Ditte Juel Adolfsen DJ Børneafdelingen, Aarhus Universitetshospital, Brendstrupgårdsvej 100, 8200 Aarhus N, Denmark. - - 2014
Children with central nervous system (CNS) tumours often have a long symptom interval before diagnosis. We investigated delays in diagnosis and surgical management after the first admission with tumour-related symptoms. This study reviewed the medical records of 46 consecutive children with a CNS tumour admitted to a paediatric department. Clinical ...
Sullivan Peggy S PS Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, - - 2014
Limited studies have examined the impact of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and specifically the category of atypia or follicular lesion of undetermined significance (AUS/FLUS). We studied their effects on reporting rates, subsequent management, and surgical outcome over a 10-year period, 5 years before and after implementation ...
Dong Y Y Department of Ultrasound, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai 200032, - - 2014
To evaluate whether contrast-enhanced ultrasound (CEUS)-guided radiofrequency ablation (RFA) can be performed effectively in small hepatic malignancies that are invisible or poorly visualized at traditional grey-scale ultrasonography (US). The institutional ethics committee approved the study, and all patients provided written informed consent before their enrolment. The study focused on 55 ...
Grantham Jared J JJ The Kidney Institute, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS, 66160, USA, - - 2014
In hereditary cystic disorders, renal injury begins with the formation of the first cyst. Renal injury may manifest as large kidneys, abdominal pain, hypertension and hematuria in children and young adults with autosomal dominant polycystic kidney disease (ADPKD). In autosomal recessive PKD (ARPKD) and ADPKD, cysts form primarily in collecting ...
Mannion Melissa L ML Division of Rheumatology, Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama, - - 2014
The Food and Drug Administration report of an increased rate of malignancy among children treated with tumor necrosis factor inhibitors is worrisome. These concerns prompted rigorous studies of the incidence of malignancy associated with juvenile idiopathic arthritis, both with and without treatment with specific therapeutic agents. This article reviews studies ...
Jivanescu Anca A Assistant Professor, Department of Prosthodontics, Faculty of Dentistry, University of Medicine and Pharmacy "Victor Babes,", Timisoara, - - 2014
The aim of this exploratory study was to evaluate the effects of hydrogel patch wound dressing on healing time and pain level of denture-related lesions of the oral mucosa in edentulous individuals. Twenty-three adults with newly fabricated complete sets of dentures who subsequently developed at least two ulcerative lesions related ...
Imai Atsushi A Department of Obstetrics and Gynecology, Matsunami General Hospital, Gifu 501-6062, - - 2014
Ovarian remnant syndrome (ORS) is a rare, but well-known gynecological complication, most often induced by difficult bilateral salpingo-oophorectomy (BSO) procedures that leave residual ovarian tissue on the pelvic wall. The most common preexisting conditions for this complication include endometriosis, pelvic inflammatory disease and prior abdominal surgery. The residual ovarian tissue ...
Carter William E WE Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, PO Box 980661, Richmond, VA 23298. - - 2014
Across the medical literature, delayed diagnosis and treatment leads to more costly and worse outcomes. Rehabilitation patients, especially those with polytrauma, often have a complex mixture of medical, social, and psychological health problems that can impair effective diagnosis and treatment. The case presentation describes the procession toward the diagnosis of ...
Pariza G - - 2014
Spontaneous umbilical endometriosis, also known as Villar’s nodule, is an unusual location of the endometrial tissue.Whilst in the case of umbilical locations secondary tosurgical procedures endometriosis occurs quite frequently,the frequency of the primary umbilical location is lowerthan 1% of all endometriosis locations. The authors presentsuch a case diagnosed in a ...
Rodríguez Cruz Pedro M PM Centre for Neuromuscular and Neurological Disorders, Western Australian Neuroscience Research Institute, Perth, Australia; Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, - - 2014
Although there have been several previous reports of immunohistochemical staining for MHC antigens in muscle biopsies, there appears to be a lack of consensus about its routine use in the diagnostic evaluation of biopsies from patients with suspected inflammatory myopathy. Positive MHC-I staining is nonspecific but is widely used as ...
Daoussis Dimitrios D Dimitrios Daoussis, Andrew P Andonopoulos, Division of Rheumatology, Department of Internal Medicine, University of Patras School of Medicine, 26504 Patras, - - 2014
We present a case of an elderly man, who initially presented with right facial nerve palsy, ipsilateral headache, elevated erythrocyte sedimentation rate (ESR) and no fever. A presumptive diagnosis of giant cell arteritis was made and the patient was treated with high-dose steroids. A temporal artery biopsy was negative. Several ...
Yeh C-F CF Department of Otolaryngology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd, Taipei, 11217, Taiwan, - - 2014
Acute pharyngitis is a common disease. However, acute pharyngitis caused by Klebsiella pneumoniae with a gross appearance mimicking hypopharyngeal malignancy has never previously been reported. We report the case of a 57-year-old man with a right hypopharyngeal tumor which was disclosed by fiberoptic laryngoscopy and computed tomography scan. However, both ...
Myatt Rebecca R Thoracic surgery, Guy's Hospital, - - 2014
Pleural effusions occur when fluid accumulates between the visceral and parietal pleura in the chest cavity, preventing the lung from expanding fully during inspiration. The reduction in lung volume, depression of the diaphragm and reduced chest wall compliance cause dyspnoea, and occasionally pain or cough. Pleural effusion is a complex ...
Teirstein Paul S PS Scripps Clinic, Division of Cardiovascular Diseases, La Jolla, CA, - - 2014
Objectives: To report 1- and 2-year clinical outcomes of patients receiving platinum chromium everolimus-eluting stents (PtCr-EES) in the prospective, single-arm PLATINUM small vessel (SV) and long lesion (LL) studies. Background: Small vessel diameter and long lesion length are independently associated with increased risk of adverse cardiac events after drug-eluting stent ...
Shimizu Akira A Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, - - 2014
A 24-year-old healthy Japanese female was diagnosed as having bowenoid papulosis in the genital area. The histopathological findings revealed acanthosis, papillomatosis, dyskeratotic cells and clumping cells with mild atypical nuclei. Human papillomavirus type 16 was detected in the lesion. The lesion was successfully treated with topical imiquimod 5% cream after ...
Le P P Department of Medical Oncology, Jewish General Hospital (a McGill University affiliate), Montreal, - - 2014
Perivascular epithelioid cell tumours (pecomas) are rare mesenchymal tumours. Some have a benign course; others metastasize. Treatment of malignant pecomas is challenging, and little is known about treatment for patients with metastatic disease. Here, we report a case of metastatic malignant pecoma with estrogen and progesterone receptor expression that showed ...
Mattos Juliana - - 2014
Traditionally, deep carious lesions are treated by removal of all carious tissue, which may lead to pulp exposure. To minimize this risk, conservative carious tissue removal techniques have been proposed, including partial removal and stepwise excavation. However, there is no consensus in the literature about which is the better technique. ...
Milicić Valerija - - 2014
Small cell carcinoma of the lung (SCLC) together with the large cell neuroendocrine carcinoma (LCNEC), typical carcinoid (TC), and atypical carcinoid (AC) make a group of morphologically identifiable neuroendocrine tumors. The differential diagnosis of SCLC includes, first of all, other neuroendocrine tumors, and primary or metastatic non-small cell carcinomas. Although ...
Sellera Fábio Parra FP College of Veterinary Medicine, University of São Paulo (FMVZ/USP), São Paulo, - - 2014
Pododermatitis is currently one of most frequent and important clinical complications in seabirds kept in captivity or in rehabilitation centers. In this study, five Magellanic penguins with previous pododermatitis lesions on their footpad were treated with photodynamic therapy (PDT). All PDT treated lesions successfully regressed and no recurrence was observed ...
Bentley P P Division of Brain Sciences, Imperial College London, London, - - 2014
Strokes caused by lesions to certain brain areas are associated with poor outcome, which is important both prognostically and to understand the neural basis for recovery. However, lesion anatomy associations with outcome may occur because of effects on baseline severity rather than because of effects on recovery per se. Here, ...
Lee Seung Hyun - - 2014
To determine the indications and the diagnostic accuracy of vacuum-assisted breast biopsy (VABB) under ultrasonographic (US) guidance based on a 10-year period of clinical use. Material and. This was a retrospective analysis of 2920 breast lesions in 2477 consecutive patients who underwent US-guided VABB between February 2002 and December 2011. ...
Bodensteiner John B JB Division of Child and Adolescent Neurology, Mayo Clinic, Rochester, MN. Electronic address: - - 2014
A four year old with a diagnosis of congenital infection leading to cerebral palsy is presented. The patient instead has a condition called Leukoencephalopathy with bilateral temporal lobe cysts which can be differentiated from congenital CMV by the clinical and MRI findings.
Wildhaber Barbara E BE Hôpitaux Universitaires de Genève, Department of Pediatrics, Division of Pediatric Surgery, 6 Rue Willy Donzé, 1205 Geneva, Switzerland. Electronic address: - - 2014
Clinical experience shows that the primary diagnosis of mesenchymal hamartoma (MHL) and embryonal sarcoma of the liver (ESL) recurrently is mistaken, leading to inadequate managements. We evaluated the accuracy of the primary diagnosis of those liver tumors, compared with the final histological diagnosis. Records of 25 children (0-16 years, treated ...
Alvarez P P Department of Oral and Maxillofacial Surgery, University of California San Francisco, USA; Division of Neuroscience, University of California San Francisco, - - 2014
Chronic pain is the most common and disabling feature of endometriosis. Surgical excision of endometriosis lesions provides relief but pain relapse is common. Studies in a preclinical model of endometriosis might help to unravel the role of the ectopic lesions as the source of pain. Thus, we evaluated the impact ...
Kiernan Colleen M CM Department of General Surgery, Vanderbilt University, Nashville, TN, USA, - - 2014
The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) was developed to refine fine-needle aspiration (FNA) cytology definitions and improve clinical management. This study evaluates the impact of the BSRTC 5 years after its adoption at a single institution. A total of 1,625 patients undergoing thyroidectomy in the pre-BSRTC (Group 1: July ...
Green Adam L AL Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; - - 2014
The prognosis of pediatric adrenocortical carcinoma often depends on prompt diagnosis to begin treatment before metastatic progression. We discuss a girl who presented at 8 months of age with virilization, which was thought to be due to exposure to a topical testosterone preparation being used by her father. Her testosterone ...
Robison Nathan J NJ Pediatric Neuro-Oncology Program, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, 4650 W Sunset Blvd, MS#54, Los Angeles, CA, 90027, USA, - - 2014
Diffuse intrinsic pontine glioma (DIPG) is a disease of childhood whose abysmal prognosis has remained unchanged for over 50 years. Biologic investigation has been stymied by lack of pretreatment tissue, as biopsy has been reserved for atypical cases. Recent advances in surgical and molecular-analytic techniques have increased the safety and potential ...
Reddy N Raghavendra NR Department of Periodontics, K.S.R Institute of Dental Sciences, Tiruchengode, Tamilnadu, - - 2014
Pregnancy tumor is a benign, hyperplastic lesion of the gingiva, considered to be reactive or traumatic rather than neoplastic in nature. The term pyogenic granuloma is a misnomer as it is not filled with pus or granulomatous tissue histologically. It is multi factorial in nature, which shows an exaggerated response ...
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