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Mancini Nicasio N Laboratory of Microbiology and Virology, University Vita-Salute San Raffaele, Via Olgettina 58, 20132, Milan, Italy, - - 2015
The need of rapid and sensitive diagnostic techniques for sepsis is every day more compelling. Its morbidity and mortality loads are dramatically high, with one quarter of patients eventually dying. Several diagnostic progresses have been made in the last years using both molecular- and nonmolecular-based approaches, and they have to ...
Micheletti Robert G RG Departments of Dermatology and Medicine, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: - - 2015
Small vessel vasculitis in the skin manifests with palpable purpura on the lower extremities. This clinical presentation prompts a complete physical examination, history, and review of systems, as well as biopsies for routine processing and direct immunofluorescence to confirm the diagnosis. The presence of vasculitis in other organs, associated underlying ...
Liu Zhuqing Z Department of Medical Oncology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, P.R. - - 2014
Primary malignant melanoma (MM) of the uterine cervix is a rare neoplasm and the overall prognosis of patients with this disease is poor. Immunohistochemical methods and exclusion of other primary melanoma sites are used to confirm the diagnosis. In the present study, the case of a 65-year-old female patient with ...
Requena Camila Bueno CB Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp), Botucatu, SP, - - 2014
Malignant syphilis is an uncommon manifestation of secondary syphilis, in which necrotic lesions may be associated with systemic signs and symptoms. Generally it occurs in an immunosuppressed patient, mainly HIV-infected, but might be observed on those who have normal immune response. Since there is an exponential increase in the number ...
Sar-Pomian Marta M Department of Dermatology, Medical University of Warsaw, Warsaw, - - 2014
Trichoscopy is becoming increasingly popular in diagnosing hair and scalp diseases. Scalp involvement in pemphigus is common. The scalp may be the first or only site of clinical manifestation of the disease. The aim of this study was to analyze whether trichoscopy may be useful in aiding differential diagnosis of ...
Sarkis L M LM 1University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards 2Department of Anatomical Pathology, Royal North Shore Hospital and Cancer Diagnosis and Pathology Group, Kolling Institute, University of Sydney, Sydney, NSW, - - 2014
Fine needle aspiration biopsy (FNAB) is the initial investigation of choice for thyroid nodules. The Bethesda system, which classifies thyroid FNABs into different categories each linked to a risk of malignancy, has been widely adopted. However, the risk of malignancy implied by each Bethesda category is likely to vary due ...
Ma Dong-Lai DL Peking Union Medical College Hospital, Beijing, China - - 2014
A previously well 34-year-old man presented with multiple plaques on his face, groin and penis, and legs. The patient reported a history of multiple unprotected sexual encounters over the preceding 2 years. A diagnosis of annular secondary syphilis was made.
Dos Santos T R TR Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio De Janeiro, RJ, - - 2014
Malignant syphilis is an uncommon, but not unknown, ulcerative variation of secondary syphilis. The lesions typically begin as papules, which quickly evolve to pustules and then to ulcers with elevated edges and central necrosis. It is usually, but not mandatory, found in patients with some level of immunosuppression, such as ...
Das Dilip K DK Department of Pathology, Faculty of Medicine, Kuwait University, Safat, Kuwait; Cytology Unit, Mubarak Al-Kabeer Hospital, Safat, - - 2014
Tuberculosis and carcinomatosis are the two most frequent causes of pleural effusion and exudative ascites, and both are characterized by lymphocyte-rich effusion. We attempted to discover if there is any significant difference in the age and sex distribution between patients presenting with these two conditions. A total of 161 serous ...
Birinyi Paul V PV Department of Neurological Surgery, Saint Louis University School of Medicine, 3635 Vista Avenue, St Louis, MO, 63110, - - 2014
We report a case of a four-year-old male who presented with symptoms of brainstem compression and lower cranial nerve neuropathies. MRI revealed a large, pre-pontine mass causing brainstem compression with an uncertain intra-axial component. Using diffusion tensor imaging (DTI) tractography and other imaging modalities, we were able to confirm that ...
Momeni Boroujeni Amir A 1Department of Pathology, SUNY Downstate Medical Center , Brooklyn, NY , - - 2014
Background: Chorangiomatosis is a unique placental vascular abnormality that can cause growth retardation and even fetal demise in severe cases. In this study we aim to better understand this lesion and the possible clinical implications. Methods and Materials: In this study 170 placentas were evaluated, both grossly and microscopically. The ...
Rabadi M H MH Department of Neurology at Oklahoma University and Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, - - 2014
Objectives:This observational study aimed to determine the types of urological lesion encountered in veterans with traumatic spinal cord injury (SCI) with neurogenic bladder (NGB), and the usage of bladder management programs to deal with NGB.Setting:NGB (detrusor muscle and urethral sphincter dysfunction with loss of bladder sensation to void) is common ...
Galassi Alfredo R AR aCatheterization Laboratory and Cardiovascular Interventional Unit, Department of Medical Sciences and Pediatrics, Division of Cardiology, Cannizzaro Hospital, University of Catania, Italy bFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia cCardiology Unit, October 6th University, Cairo, - - 2014
Bifurcation lesions represent a distinct lesion subset associated with an increased risk of procedural complications. Data on the incidence, treatment, and outcome of bifurcation lesions associated with chronic total occlusions are limited. Among chronic total occlusion procedures performed by a single experienced operator, patients with a bifurcation lesion within the ...
Schneider M M MM Department of Orthopaedic Surgery, Traumatology and Sports Medicine, Cologne Merheim Medical Center (CMMC), University of Witten/Herdecke, Ostmerheimer Str. 200, 51109, Cologne, Germany, - - 2014
The reliability of the Rockwood classification, the gold standard for acute acromioclavicular (AC) joint separations, has not yet been tested. The purpose of this study was to investigate the reliability of visual and measured AC joint lesion grades according to the Rockwood classification. Four investigators (two shoulder specialists and two ...
Sciacca Sara S Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK, - - 2014
Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic proliferative disorder commonly involving the cervical lymph nodes and less frequently extranodal sites, including, rarely, the central nervous system, mainly intracranially. Spinal involvement is unusual. RDD is characterized by pathognomonic histopathological features, which are decisive in the definitive diagnosis. We present the ...
Braun Jurgen J From the Rheumazentrum Ruhrgebiet, Herne; Rheumatologie, Universitätsmedizin Charité, Berlin, Germany. J. Braun, MD, Professor; X. Baraliakos, MD; U. Klitz, MD; F. Heldmann, MD; Rheumazentrum Ruhrgebiet; J. Sieper, MD, Professor, Rheumatologie, Universitätsmedizin Charité. Address correspondence to Prof. Dr. J. Braun, Rheumazentrum Ruhrgebiet, Claudiusstrasse 45, 44649 Herne, Germany. E-mail: juergen.braun@elisabethgruppe.de. Accepted for publication April 9, - - 2014
The Assessment of Spondyloarthritis international Society (ASAS) classification criteria for axial spondyloarthritis (axSpA) have added nonradiographic axSpA (nr-axSpA) to the classic ankylosing spondylitis (AS) as defined by the modified New York criteria. However, some confusion remains about differences between classification and diagnosis of axSpA. Our objective was to analyze differences ...
Muriithi Ruth W RW Kenyatta National Hospital, University of Nairobi, Nairobi, - - 2014
Objective: To describe the cytological findings of the esophagus using sponge cytology as a triage test in patients referred for esophageal endoscopy at Kenyatta National Hospital. Study Design: A cross-sectional descriptive study was undertaken to obtain specimens from the esophagus for cytological evaluation using a sponge. The cellular yield and ...
Liu K K Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, - - 2014
PurposeTo assess the value of histopathologic investigations of vitreous biopsy specimens in the diagnosis of fungal endophthalmitis compared with that of conventional smear and fungal culture.MethodsIn this prospective study, 10 patients with clinically suspected fungal endophthalmitis of any etiology underwent intravitreal sampling and vitrectomy for diagnostic and therapeutic purposes. Infused ...
Neittaanmäki-Perttu Noora N Department of Dermatology and Allergology, Helsinki University Central Hospital, FIN-00029 Helsinki, Finland. - - 2014
Lentigo maligna (LM) is an in situ form of melanoma which can progress into invasive lentigo maligna melanoma (LMM). Variations in the pigmentation and thus visibility of the tumour make assessment of lesion borders challenging. We tested hyperspectral imaging system (HIS) in in vivo preoperative delineation of LM and LMM ...
Grigorescu Ioana I Ioana Grigorescu, Dan Lucian Dumitrascu, 2 Department of Internal Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400006 Cluj-Napoca, - - 2014
To describe spontaneous, or interferon (IFN)- or immunization-induced skin lesions in hepatitis B virus (HBV) infection. A comprehensive literature search of all the papers presenting case reports of dermatological lesions in patients with chronic HBV infection was carried out. We included only patients with histologically proven skin lesions that appeared ...
Grosu Horiana B - - 2014
Bronchoscopy in patients with space-occupying brain lesions is anecdotally felt to carry a high risk of neurologic complications. We conducted a retrospective cohort study of patients with evidence of malignant space-occupying brain lesion that were referred for flexible or rigid bronchoscopy or endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The primary ...
Moon In Soo IS Department of Radiology , Busan Paik Hospital, Inje University School of Medicine, Busan, South - - 2014
No previous ultrasound (US) studies have investigated the diagnostic accuracy of specific US-based diagnostic protocol for cervical lymph node (LN) lesions in a tuberculosis-endemic area. This study aimed to assess the accuracy of US-based diagnosis of cervical LNs in a tuberculosis-endemic area. This was a retrospective cohort study. We enrolled ...
Mizrachi Yossi Y Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, 62 Halochamim Street, Holon, - - 2014
Laparoscopy has become the standard of care in the management of ovarian benign mucinous cystadenomas. One concern of the operative approach is the risk of recurrence. A previous study has found intraoperative cyst rupture and cystectomy to be the risk factors for recurrence. Our objective was to assess the incidence ...
Macias Carlos Aitor CA Department of Surgery, Lenoir Memorial Hospital, Kinston, NC, - - 2014
Thyroid nodules are present in 19-67 % of the population and have a 5-10 % risk of malignancy. Fine needle aspiration biopsies are indeterminate in 20-30 % of patients, often necessitating thyroid surgery for diagnosis. We hypothesized that developing a risk model incorporating factors associated with malignancy could help predict the risk of ...
El-Zahry Mai R MR Department of Nuclear Medicine, Medical University of Vienna, Austria. - - 2014
Focal tracer uptake in the jaw during conventional bone scintigraphy is a quite frequent finding usually due to dental disease and seldom to other diseases including malignant disease. Methylene diphosphonate-technetium-99m ((99m)Tc-MDP) 3-phase bone scan is considered the most sensitive imaging method for the detection of jaw osteonecrosis at an early ...
Li Yunxiang - - 2014
We present a case of a patient with malignant melanoma of the glans penis and urethra, which was found in a 53-year-old man with nonhealing ulcerative penile lesion and bilateral, clinically palpable inguinal lymphadenopathies at diagnosis. A diagnostic biopsy showed the characteristics of a melanoma. We treated the patient with ...
Marta Liliana L Hospital da - - 2014
Congenital pericardial absence is a rare cardiac defect. Although most patients are asymptomatic, recognising this condition is clinically important as it can cause serious complications. We report the case of an asymptomatic 33-year-old woman seeking medical attention due to a family history of sudden cardiac death. The investigation led us ...
Fawzi Amani A AA *Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; †Wolfe Eye Clinic, West Des Moines, Iowa; ‡Rothschild Foundation, Paris, France; §F. I. Proctor Foundation, University of California, San Francisco, California; ¶Uveitis Unit, Department of Ophthalmology, Chulalongkorn University, Bangkok, Thailand; **Department of Ophthalmology, Houston Methodist Hospital, Houston, Texas; and Departments of ††Ophthalmology, and ‡‡Radiation Oncology, Weill Cornell Medical College, Houston, - - 2014
To describe multimodal imaging findings in patients with dark or white without pressure lesions of the fundus. Retrospective observational case series of 10 patients with white or dark without pressure lesions. We analyzed multimodal imaging using spectral domain optical coherence tomography, color and near-infrared fundus photography, and fundus autofluorescence imaging ...
Türk Cezmi Cağrı CC Neurosurgery Clinic, Antalya Education and Research Hospital, Antalya, 07050, Turkey, - - 2014
Lesions initially presenting as a scalp mass are quite common entities with a wide spectrum of causes. They may be directly related to the scalp itself or may be secondary stigmata of an underlying process in the skull. The rate and clinical significance of the differential diagnosis of these lesions ...
Bryce Adam S AS School of Medicine, University of Glasgow, Glasgow, G12 8QQ, - - 2014
Colonoscopy detects colorectal cancer and determines lesion localisation that influences surgical planning. However, published work suggests that the accuracy of lesion localisation can be low as 60 %, with implications for both the surgeon and the patient. This work aims to identify potential influencing factors at colonoscopy that could lead to ...
Lefranc Michel M Department of Neurosurgery, Centre Hospitalier Universitaire Amiens, - - 2014
OBJECT Stereotactic biopsy procedures are an everyday part of neurosurgery. The procedure provides an accurate histological diagnosis with the least possible morbidity. Robotic stereotactic biopsy needs to be an accurate, safe, frameless, and rapid technique. This article reports the clinical results of a series of 100 frameless robotic biopsies using ...
Makras Polyzois P Department of Endocrinology and Diabetes, 251 Hellenic Air Force & VA General Hospital, Athens, - - 2014
Context: Langerhans Cell Histiocytosis (LCH) is a rare disease exhibiting both neoplastic and inflammatory features including abundant cytokine secretion both at the lesional and systemic level. Objective: Evaluation of RANKL expression within LCH lesions in various tissues. Design: Cross-sectional study involving paraffin blocks from the diagnostic biopsies of adults with ...
Nguyen Andrew H AH Department of Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, CHS 72-215, Los Angeles, CA, 90095, - - 2014
The 2012 Sendai Criteria recommend that patients with 3 cm or larger branch duct intraductal papillary mucinous neoplasms (BD-IPMN) without any additional "worrisome features" or "high-risk stigmata" may undergo close observation. Furthermore, endoscopic ultrasound (EUS) is not recommended for BD-IPMN <2 cm. These changes have generated concern among physicians treating patients with ...
Xia Hong-Tian HT Hospital and Institute of Hepatobiliary Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, 100853, Beijing, China, - - 2014
Our purpose was to evaluate the reasons for reoperations and outcomes in patients with choledochal cysts (CCs). The records of patients with CCs who underwent reoperations from 1995 to 2012 were retrospectively reviewed. Of 165 patients with a mean age of 42.54 ± 14.05 years, 62 had Todani type I (37.6 %), 84 type ...
Lippert Dylan D University of Wisconsin-Madison School of Medicine and Public Health, Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Madison, Wisconsin, - - 2014
Definitive tissue diagnosis for lesions warranting biopsy is shifting from the operating room to the office. Safety, tolerance, factors related to successful biopsy, and time to treatment are not well-defined. Retrospective review of 116 patients undergoing in-office biopsy of oropharynx, larynx, or hypopharynx were included. Logistic regression determined if demographics, ...
Esmat Samia M SM *All the authors are affiliated with the Department of Dermatology, Kasr El Aini Hospital, Cairo University, Cairo, - - 2014
Xanthelasma palpebrarum (XP) is a common cosmetic concern. Although there is a wide range of therapeutic modalities for XP, there is no general consensus on the optimal treatment for such condition. Compare the efficacy and safety of super pulsed (SP) and fractional CO2 lasers in the treatment of XP. This ...
Mehra Rohit R Department of Surgery, Armed Forces Medical College, Pune, Maharashtra, - - 2014
Paraduodenal hernia (PDH), a rare congenital anomaly, is a type of internal hernia which occurs due to a defect in the reduction and rotation of the midgut. On anatomical and embryological basis, PDH can be broadly divided into right- and Left PDH. Right PDH is rarer than its counterpart. We ...
Kini Jyoti R JR Department of Pathology, Kasturba Medical College, Manipal University, Mangalore, KARNATAKA, - - 2014
Lipofibromatous hamartoma is a rare tumour-like condition involving the peripheral nerves, particularly the median nerve. It commonly affects the volar aspect of the hands, wrists and forearms of young adults. Most patients present either early with macrodactyly or later with a forearm mass lesion or symptoms consistent with compressive neuropathy ...
Courtois F F Department of Sexology, Université du Québec à Montréal, Succ Centre-ville, Montreal, Quebec, - - 2014
Study design:Retrospective study.Objectives:Spinal cord injuries are usually associated with anejaculation, but few premature ejaculations (PE) are described in lumbosacral lesions. The objective of the study is to analyze the retrospective files of patients with lumbosacral lesions to explore whether PE is systematic, and which type of lesions (conus teminalis, epiconal, ...
Pamuk Gulsum Emel GE Division of Haematology, Trakya University Medical Faculty, Edirne, - - 2014
We evaluated the clinical characteristics of patients with haematological malignancies at our centre who were diagnosed with leukaemia cutis (LC). In addition, we describe the spectrum of other skin lesions, including, secondary skin malignancies and nonspecific benign skin lesions in haematological malignancy patients. We defined 58 skin lesions that developed ...
Chen Hsin-Ming HM Graduate Institute of Clinical Dentistry, National Taiwan University, Taipei, Taiwan; Graduate Institute of Oral Biology, National Taiwan University, Taipei, Taiwan; School of Dentistry, National Taiwan University, Taipei, Taiwan; Department of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, - - 2014
Our previous study has shown that cryogun cryotherapy is a good and effective treatment modality for oral leukoplakia. In this study, we used cryogun cryotherapy to treat 72 oral leukoplakia and adjacent smoking-induced melanosis (OLM) lesions on the buccal mucosae. Of 72 OLM lesions, 14 had epithelial hyperplasia with parakeratosis, ...
Basaran Recep R Department of Neurosurgery, Dr. Lutfi Kirdar Kartal Education and Research Hospital , Istanbul , - - 2014
Objective. Arachnoiditis is an inflammatory process resulting with the fibrosis of arachnoid mater. It can vary in severity from mild thickenings to catastrophic adhesions that ruins subarachnoid space. As a result, arachnoid cysts can be formed. Arachnoid cyst induced by symptomatic spinal arachnoiditis is a rare complication of subarachnoid haemorrhages. ...
Krishnamohan Prashanth P Department of Neurology, University of Kentucky College of Medicine, 740 S. Limestone St., Lexington, KY, 40536-0284, - - 2014
Spinal epidural abscess (SEA) remains a relatively infrequent diagnosis. Staphylococcus aureus is the most common organism identified, and the infectious source in SEA emanates from skin and soft tissue infections in about 20 % of instances. The thoracic spine is most often involved followed by the lumbar spine. The classic triad ...
Gong Zhaohua Z Department of Oncology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong 264000, P.R. - - 2014
Primary penile lymphoma presenting with priapism as the initial symptom is extremely rare. In total, <10 cases have been previously reported. The diagnosis can be difficult and patients often develop metastasis. The current study reports the case of a 48-year-old male, who presented with a one-month history of painless priapism. ...
Xing Dejun D Department of Medical Oncology, Jilin Cancer Hospital, Changchun, Jilin 130012, P.R. - - 2014
A benign lymphoepithelial lesion (BLEL) is an idiopathic inflammation of the parotid gland, characterized by hyperplasia, lymphocyte infiltration and the formation of epimyoepithelial islands, as well as atrophy of the gland parenchyma. Common treatment methods include immunosuppression and glucocorticoid therapies, in addition to surgical dissections. Cytokine-induced killer (CIK) cells sensitized ...
Johannesma Paul Christiaan PC Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The - - 2014
The development and natural course of lung cysts in patients with Birt-Hogg-Dubé syndrome (BHD) is still unclear, and the relationship between lung cysts and pneumothorax is not fully clarified. Based on the follow-up results of thoracic imaging in six patients with BHD, we hypothesize that decreased potential for stretching of ...
Licci Stefano S From Department of Pathology, "Santo Spirito" Hospital, Rome, Italy; - - 2014
Lymphangiomas are relatively uncommon lesions of the lymphatic channels that can arise in virtually any part of the body provided by lymphatic vessels. The most common localization is the head/neck region, with only sporadic reports in other sites. The mediastinum is a rare location, with around 20 cases reported in ...
Putra Juan J Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United - - 2014
A 59-year-old man with T-cell prolymphocytic leukemia on alemtuzumab presented with neutropenic fever, intermittent nausea, and multiple ill-defined low attenuation foci in the liver on abdominal computed tomography scan which were suspicious for metastatic disease. Histological examination revealed the diagnosis of adenovirus hepatitis. Patient responded well to cidofovir. Adenovirus hepatitis ...
Ruiz-Morales Jose M JM Oncology center. Medica Sur Hospital. Mexico City, - - 2014
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and is the fifth most common cancer in the world; its incidence has been increasing in recent years. Extrahepatic spread is present at the time of diagnosis in only about 5 to 15% of patients. Skeletal metastasis of ...
Groszmann Yvette Y Diagnostic Ultrasound Associates, PC, Boston Massachusetts USA (Y.G., B.B., B.R.B.); Departments of Obstetrics and Gynecology (Y.G., B.B., C.M.F., B.R.B.), Pathology (B.E.H.), and Radiology (B.B., B.R.B.), Brigham and Women's Hospital, Boston, Massachusetts USA; Department of Obstetrics and Gynecology, Dana Farber Cancer Institute, Boston, Massachusetts USA (B.B., C.M.F., B.R.B.); and Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts USA (B.B., B.R.B.). - - 2014
To identify the sonographic features of decidualized endometriomas in patients treated at a single institution and to determine whether sonographic findings can distinguish these lesions from malignant ovarian tumors during pregnancy. We conducted a retrospective cohort study that included pregnant women with a histologic diagnosis of decidualized endometrioma between January ...
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