Search Results
Results 1 - 50 of 1740
1 2 3 4 5 6 7 8 9 10 >
Krishnan Pramod P Department of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore, - - 2014
There are only a few studies describing the etiologic spectrum of biopsy-proven peripheral neuropathies in children. This study reviewed the clinical, electrophysiological, and pathologic profile of 239 children (≤18 years of age) who have undergone nerve biopsy in a tertiary care centre for neurologic disorders and analyzed the etiologic spectrum ...
Gluf Wayne M - - 2014
Context Hemangioblastomas of the spinal cord are uncommon vascular tumors. Patients commonly present with subtle neurologic findings that are thought to represent growth of the lesion over time. Hemorrhage of an intramedullary hemangioblastoma presenting as acute neurologic deficit is an extremely rare occurrence. Although the cervical spine is the most ...
Gagliardo Anna A Department of Biology, University of Pisa, Via Volta 6, 56126, Pisa, - - 2014
The importance of the vertebrate hippocampus in spatial cognition is often related to its broad role in memory. However, in birds, the hippocampus appears to be more specifically involved in spatial processes. The maturing of GPS-tracking technology has enabled a revolution in navigation research, including the expanded possibility of studying ...
Zhang Yongsheng Y Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, - - 2014
Lesion analysis is a classic approach to study brain functions. Because brain function is a result of coherent activations of a collection of functionally related voxels, lesion-symptom relations are generally contributed by multiple voxels simultaneously. Although voxel-based lesion-symptom mapping (VLSM) has made substantial contributions to the understanding of brain-behavior relationships, ...
Furuya Kazuhide K Departments of Neurosurgery - - 2014
The authors report the case of an 11-year-old immunocompetent boy with primary CNS CD30-positive anaplastic large-cell lymphoma (ALCL) that was also positive for anaplastic lymphoma kinase-1. His initial clinical manifestation was acute meningitis of unknown etiology. Findings on CT scanning were normal. Although he received empirical treatment against infection, his ...
Raimbault A A General Radiology - Diagnostic and Therapeutic Neuroradiology, Bretonneau Hospital, 2, boulevard Tonnellé, 37044 Tours cedex, - - 2014
Detecting a new area of contrast-enhancement at MRI after irradiation of malignant brain tumor arises the problem of differential diagnosis between tumor recurrence and radiation necrosis induced by the treatment. The challenge for imaging is to distinguish the two diagnoses given: the prognostic and therapeutic issues. Various criteria have been ...
Hasegawa Mitsuhiro M Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukak, Toyoake, Aichi, 470-1192, Japan, - - 2014
Neuroepithelial cyst is considered an unusual differential diagnosis for cysts in the posterior fossa. Here, we present a paediatric case with such a pathology and review the pertinent literature. A 12-year old girl with headache, vertigo and disturbed gait was diagnosed with a cystic lesion in the fourth ventricle after ...
Li Da D Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, - - 2014
Medulla oblongata teratomas are rare. The authors report 2 new cases of teratomas that occurred exclusively in the medulla oblongata. The first case was in a 9-year-old boy who presented with a 6-month history of neck pain and repeated paroxysmal vomiting. Based on preoperative radiographic findings, the initial diagnosis was ...
Walong Edwin - - 2014
DiGeorge syndrome may manifest as severe immunodeficiency diagnosed at infancy. The diagnosis of primary immunodeficiency is based on characteristic clinical features, immunophenotyping by flow cytometry, molecular diagnostics and functional lymphocyte evaluation. At autopsy, gross evaluation, conventional histology and immunohistochemistry may be useful for the diagnosis of primary immunodeficiency. This case ...
Arnold Douglas L DL NeuroRx Research, Montreal, QC, Canada, - - 2014
In the Phase 3 DEFINE study, delayed-release dimethyl fumarate (DMF) 240 mg twice (BID) and three times daily (TID) significantly reduced the mean number of new or enlarging T2-hyperintense lesions and gadolinium-enhancing (Gd+) lesion activity at 2 years in patients (MRI cohort; n = 540) with relapsing-remitting MS. The analyses described here expand on ...
García Cabezas Sonia S Department of Radiation Oncology, Reina Sofia University Hospital, Córdoba, Spain, - - 2014
The rosette-forming glioneuronal tumour (RGNT) is a rarely encountered tumour that has been included as a new entity in the 2007 edition of the "World Health Organization (WHO) Classification of Tumours of the Central Nervous System". We describe a rather unusual case of multifocal cerebellar RGNT, located in the spinal ...
Orguc Sebnem S Department of Radiology, Celal Bayar University, Manisa, - - 2014
Spinal tumors consist of a large spectrum of various histologic entities. Multiple spinal lesions frequently represent known metastatic disease or lymphoproliferative disease. In solitary lesions primary neoplasms of the spine should be considered. Primary spinal tumors may arise from the spinal cord, the surrounding leptomeninges, or the extradural soft tissues ...
Hardy Todd A TA Neuroimmunology Clinic, Department of Neurology, Concord Repatriation General Hospital, University of Sydney, NSW, Australia; MS Australia Clinic, Brain and Mind Research Institute, Sydney, NSW, Australia. Electronic address: - - 2014
Baló's concentric sclerosis is often regarded as a rare variant of multiple sclerosis. Patients with this disorder present with acute or subacute neurological deterioration, with MRI showing one or more concentrically multilayered ring-like lesions usually in the cerebral white matter. Historically, Baló's concentric sclerosis was thought fatal in all cases. ...
Lemercier Pierre P 1 Department of Radiology, Hospital Universitario y Politécnico la Fe, Bulevar Sur, Valencia, Spain - - 2014
OBJECTIVE. Glioblastoma and solitary metastatic lesions can be difficult to differentiate with conventional MRI. The use of diffusion-weighted MRI to better characterize peritumoral edema has been explored for this purpose, but the results have been conflicting. The purpose of this study was to test the hypothesis that the gradient of ...
Togral Guray G Department of Orthopedics and Traumatology, Oncology Training and Research Hospital, Ankara, - - 2014
Schwannomas are benign encapsulated tumors of Schwan cells that grow slowly along the peripheral myelin nerve fibers. Sacral spinal schwannomas are very rare, and the incidence of sacral schwannoma ranges from 1-5% of all spinal schwannomas, and only around 50 cases are reported in the literature. There are 3 defined ...
Salunke Pravin P Department of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2014
Olfactory region schwannomas are rare, but when they occur, they commonly arise from the meningeal branches of the trigeminal nerve and may present without involvement of the olfaction. A 24 year old lady presented with hemifacial paraesthesias. Radiology revealed a large olfactory region enhancing lesion. She was operated through a ...
Sawada Jun J Division of Neurology, Asahikawa Medical University, Japan - - 2014
A woman with Sjögren syndrome manifesting as aphasia with a left deep cerebral white matter lesion tested positive for anti-aquaporin 4 (AQP4) antibody. Open biopsy of the lesion revealed active demyelination with edematous changes and the preservation of most axons, indicating a non-necrotic demyelinating lesion. Immunostaining for AQP4 was diffusely ...
Petscavage-Thomas Jonelle M JM From the Departments of Radiology (J.M.P., E.A.W., D.M.D.) and Pathology (L.E.C.), Penn State Milton S. Hershey Medical Center, 500 University Dr, Room HG300, Hershey, PA 17033; Department of Radiology and Nuclear Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md (E.A.W., M.D.M.); Musculoskeletal Section, American Institute for Radiologic Pathology, Silver Spring, Md (C.I.L., M.D.M.); and Department of Radiology, Walter Reed National Military Medical Center, Bethesda, Md - - 2014
Myxoid soft-tissue lesions are a heterogeneous group of benign and malignant mesenchymal tumors with an abundance of extracellular mucoid material. These lesions may mimic cysts on radiologic evaluation because of the high water content, and histopathologic features also overlap. Benign myxoid lesions include intramuscular myxoma, synovial cyst, bursa, ganglion, and ...
Jagadesan Venkatesan V Department of Psychiatry, Thanjavur Medical College, Thanjavur, Tamil Nadu, - - 2014
Secondary mania resulting from cerebral Cortex are described commonly. But secondary mania produced by cerebellar lesions are relatively uncommon. This case report describes a patient who developed cerebellar stoke and manic features simultaneously. 28 years old male developed giddiness and projectile vomiting. Then he would lie down for about an ...
Thomas Jonathan G JG Department of Neurosurgery, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: - - 2014
Intradural spinal malignant peripheral nerve sheath tumors (MPNST) are extremely rare, with only 20 adult patients reported to our knowledge, and only four primary tumors arising from the cauda equina. A 49-year-old man presented with back pain, constipation, and lower extremity weakness and was found to have a large intradural ...
Mah Yee-Haur YH 1 Institute of Neurology, UCL, London, WC1N 3BG, - - 2014
Our knowledge of the anatomical organization of the human brain in health and disease draws heavily on the study of patients with focal brain lesions. Historically the first method of mapping brain function, it is still potentially the most powerful, establishing the necessity of any putative neural substrate for a ...
Laast Victoria A VA Nonclinical Safety Assessment, Covance Pharmaceutical R&D (Shanghai) Co. Ltd., Shanghai, China - - 2014
Cystic degeneration of the adrenal cortex is a common age-related finding in the Sprague-Dawley (SD) rat strain occurring more frequently in females. Compression of the adjacent cortex, a common hallmark of benign adrenal cortical tumors, often accompanies foci of cystic degeneration, creating a diagnostic challenge. Accurately differentiating these relatively common ...
Aslan Gaffar - - 2014
Schwannoma is a benign, solitary, and slowly progressive encapsulated tumor originating from the sheath of myelinated nerve fibers. Schwannoma of the salivary gland is a particularly rare form of an extracranial neurogenic tumor. Here, we present an unusual case of a schwannoma of the submandibular gland in a 19-year-old man. ...
Saettele Megan R MR Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA, - - 2014
Childhood primary angiitis of the central nervous system (cPACNS) is a rare and poorly understood immune-mediated vasculitis that preferentially affects blood vessels of the central nervous system (CNS). It must be distinguished from other disorders to initiate prompt treatment and improve the patient's prognosis. The presentation of cPACNS is highly ...
Demir Mustafa Kemal MK Department of Radiology, Bahçe┼čehir University School of Medicine, Goztepe Medical Park Hospital, Istanbul/ Turkey. - - 2014
There are many kinds of extra-axial brain tumors and tumor-like lesions, and definitive diagnosis is complicated in some cases. In this pictorial essay, we present rare and challenging extra-axial brain lesions including neuroenteric cyst, primary leptomeningeal melanomatosis, isolated dural neurosarcoidosis, intradiploic epidermoid cyst, ruptured dermoid cyst, intraventricular cavernoma, and cavernous ...
Yang Shaofeng S From the Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2014
Intracranial arachnoid cysts are rare cystic-appearing intracranial masses. In rarer cases, the arachnoid cysts originate from brain parenchyma, which is defined as intracerebral arachnoid cyst. Here, we present a patient younger than 2 years with massive intracranial arachnoid cysts (one of which was intracerebral arachnoid cyst), whose clinical symptoms included ...
Cefalo Maria Giuseppina - - 2014
Congenital cystic eye is an exceedingly rare ocular malformative disease, originated from the failure in the invagination of the optic vesicle during the fetal period and it can be associated with other ocular and non-ocular abnormalities. Diagnosis is based on clinical, radiological and histological features. We report a case of ...
Xu Jindong J Department of Neurology, University of Florida, - - 2014
A 75-year-old woman was transferred from a local hospital because of rapid progression to coma preceded by lower back pain and recurrent falls. Cerebrospinal fluid analysis at the local hospital revealed increased protein with a slightly elevated white blood cell count. Our imaging studies revealed multiple punctate foci with nodular ...
Kukreja Sunil S Department of Neurosurgery, Louisiana State University Health Sciences Center-Shreveport, Shreveport, - - 2014
The authors report the case of a spinal intradural schwannoma presenting with intracranial subarachnoid hemorrhage (SAH). Cerebral angiography did not show any intracranial lesion; however, MRI revealed two separate tumors in the lower segment of the spinal cord. The proximal lesion arising from the conus medullaris was well circumscribed and ...
Deloison Benjamin B Department of obstetric and fetal medicine, Unviversité Paris 5 Descartes, Sorbonne Paris-Cité, Assistance Publique Hôpitaux de Paris, Hôpital Necker-Enfant Malades, Paris, - - 2014
We report a rare case of oral mass (epignathus) with completely cystic appearance, without Doppler signal, offering safe conditions for cystic punction immediately before delivery. Prenatal evacuation of cystic content reduced the risk of respiratory compromise at birth by upper airway obstruction and fetal dystocia, allowing vaginal delivery without the ...
Papacostas Savvas S SS Clinical Sciences, The Cyprus Institute of Neurology and Genetics, Nicosia, - - 2014
Reports about cervical vestibular evoked myogenic potentials (cVEMPs) in central nervous system lesions are scarce. Our experience with cerebellar lesions is still evolving, with only a few cases published. The purpose of this article is to present our cVEMP findings of 3 cases with cerebellar lesions. cVEMPs were performed using ...
Hirono Seiichiro S Department of Neurological Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuoku, Chiba, 260-8670, Japan, - - 2014
Blake's pouch cyst (BPC), a rare cystic malformation in the posterior fossa, is believed to be caused by the congenital expansion of the posterior membranous area that normally regresses during embryogenesis. However, due to the wide spectrum of the onset pattern and age of patients, the natural history and the ...
Mkupasi E M EM Department of Veterinary Disease Biology,Faculty of Health and Medical Sciences, University of Copenhagen,Thorvaldsensvej 57,1871Frederiksberg - - 2014
Neurocysticercosis (NCC) caused by Taenia solium cysts is a frequent but neglected parasitic disease of the central nervous system (CNS) worldwide. The aim of this study was to describe anatomical locations of cysts in the CNS and the corresponding inflammation. A total of 17 naturally infected pigs were used to ...
Khatab Sodaba S Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The - - 2014
Studies regarding frameless stereotactic brain biopsy mainly report high diagnostic yield (DY) as opposed to relatively low diagnostic accuracy. This discrepancy raises the question of the certainty and precision of obtained diagnoses. This article proposes a DY definition encompassing diagnostic certainty and precision according to the World Health Organization (WHO) ...
Sun Lisa R LR Division of Pediatric Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland; The Neurosciences Intensive Care Nursery, The Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: - - 2014
Connatal cysts are rare but recognized periventricular cysts that represent anatomic variants and are associated with good neurological outcomes. These cysts can be differentiated from cysts that portend graver prognoses by their location in relation to the ventricles, size, laterality, and temporal resolution. We describe a preterm twin infant born ...
Chittem L L Department of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, - - 2014
Study design:We came across two patients with holocord tuberculosis exhibiting similar radiological picture, which may aid in early diagnosis.Objectives:We have described a new radiological sign for early diagnosis of intramedullary tubercular abscess.Setting:Observations from an endemic zone for tuberculosis (India).Methods:Surgical excision followed by histological and microbiological examination and retrospective correlation of ...
Yamamoto Junkoh J Department of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, - - 2014
The rapid disappearance of primary central nervous system lymphomas (PCNSL) following steroid therapy is common; however, the spontaneous regression of PCNSL without any treatment is extremely rare. This study presented a rare case of PCNSL with preceding pseudotumoral demyelination and no previous steroid treatment, and the pitfalls of PCNSL diagnosis ...
Dubey Jitender P - - 2014
A near-full-term alpaca (Vicugna pacos) was stillborn 2 days before the expected date of delivery; necropsy examination was conducted within 6 hr of delivery. Gross lesions were enlarged liver and hydrocephalus. On histologic examination, mild inflammatory lesions were identified in the placenta, liver, and lungs, although no etiology was recognized. ...
Carrera Emmanuel E 1 Department of Clinical Neurosciences, University Hospital, Geneva, Switzerland2 Department of Psychiatry, Madison, Wisconsin, USA - - 2014
After a century of false hopes, recent studies have placed the concept of diaschisis at the centre of the understanding of brain function. Originally, the term 'diaschisis' was coined by von Monakow in 1914 to describe the neurophysiological changes that occur distant to a focal brain lesion. In the following ...
Mkupasi E M EM Department of Veterinary Disease Biology,Faculty of Health and Medical Sciences, University of Copenhagen,Thorvaldsensvej 57,1871Frederiksberg - - 2014
Neurocysticercosis (NCC) caused by Taenia solium cysts is a frequent but neglected parasitic disease of the central nervous system (CNS) worldwide. The aim of this study was to describe anatomical locations of cysts in the CNS and the corresponding inflammation. A total of 17 naturally infected pigs were used to ...
Quan Chao C Huashan Hospital, Shanghai Medical College, Fudan University, - - 2014
We report the case of a patient who developed right hemiparesis with an acute onset 2 weeks before being transferred to our hospital. The brain MRI revealed multiple lesions in deep white matter; some were ovoid and perpendicular to the lateral ventricle, typical of cerebral demyelinating disease such as multiple ...
Bhatt Vijaya Raj VR Department of Internal Medicine, Division of Hematology-Oncology, University of Nebraska Medical Center, Omaha, NE, - - 2014
Primary central nervous system (CNS) lymphoma, most frequently a diffuse large B-cell lymphoma, is a rare aggressive lymphoma confined to the CNS, thus requiring differentiation from other brain malignancies such as glioblastoma. Although stereotactic biopsy can confirm the diagnosis, this is invasive, not always feasible and can be inconclusive after ...
Döring Michaela - - 2014
Congenital grouped skin lesions are alarming signs of a variety of threatening diagnoses of quite different origin. The present case report shows an impressive clinical pattern of a neonate and illustrates the difficulty in differential diagnosis of mixed connective tissue disease and neonatal lupus erythematosus in newborns. This reported case ...
Lu A Y AY Department of Neurosurgery, Yale School of Medicine, New Haven CT 06510, United - - 2014
Melanoma lesions in the brainstem can be difficult to distinguish radiographically and clinically from cavernous malformations. However, the treatment modalities and clinical course of these two diseases differ considerably. We report two cases of melanoma presenting as brainstem hemorrhages. A 69-year-old male was found to have a hemorrhagic lesion of ...
Warade Abhijit G AG Department of Neurosurgery & Gamma Knife Radiosurgery, P.D. Hinduja Hospital & Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai 400016, Maharashtra, - - 2014
Spinal glioblastoma multiforme is a rare entity comprising 1.5% of all spinal cord tumors. We report a 57-year-old man presenting with a 1.5month history of left sided radiculopathy, lower cranial nerve weakness and difficulty in walking. MRI of the brain and spine showed an exophytic intramedullary lesion extending from the ...
Shams Pari N PN *Department of Ophthalmology and Visual Sciences, Vancouver Hospital Eye Care Centre and University of British Columbia; and †Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, British Columbia, - - 2014
Adult xanthogranulomatous disease involving the ocular or orbital tissues is rare. The authors present a 63-year-old asthmatic woman with progressive left eyelid ptosis and fatigue in whom this diagnosis was clinically suspected on the basis of the characteristic waxy indurated yellow periocular and conjunctival lesions. These findings prompted an incisional ...
De La Hoz Polo M M Servicio de Radiodiagnóstico, Hospital Universitario Mútua Terrassa, Terrassa, Barcelona, España; Servicio de Radiología Pediátrica, Hospital San Joan de Déu, Esplugues de Llobregat, Barcelona, España. Electronic address: - - 2014
Langerhans cell histiocytosis (LCH) is a rare disease characterized by the accumulation within tissues of anomalous dendritic cells similar to Langerhans cells. The clinical presentation varies, ranging from the appearance of a single bone lesion to multisystemic involvement. Central nervous system (CNS) involvement, manifesting as diabetes insipidus secondary to pituitary ...
Sciacca Pietro - - 2014
Rhabdomyomas are the most common type of cardiac tumors in children. Anatomically, they can be considered as hamartomas. They are usually randomly diagnosed antenatally or postnatally sometimes presenting in the neonatal period with haemodynamic compromise or severe arrhythmias although most neonatal cases remain asymptomatic. Typically rhabdomyomas are multiple lesions and ...
Hall Brian J BJ *St Alphonsus Hospital, Boise, ID †Department of Pathology and Dermatology, University of California, San Francisco, San Francisco, - - 2014
Multiple criteria on routinely stained sections allow one to make a diagnosis of a dysplastic or "Clark" nevus (CN) versus melanoma in situ (MIS), and one of these is suprabasal spread of melanocytes. The extent of suprabasal spread of melanocytes in otherwise conventional CN and the combination of a sensitive ...
Mendes Gustavo B GB Neuroinfection Clinic, Hospital Universitário Gaffré e Guinle/Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, - - 2014
Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic inflammatory disease of the spinal cord, characterized by spastic paraparesis, back pain, and sphincter disorders. Involvement of multiple organs and encephalopathy are uncommon in HAM/TSP. Nonspecific small white matter lesions of unknown etiology, mainly in the periventricular ...
1 2 3 4 5 6 7 8 9 10 >