Search Results
Results 1 - 50 of 2641
1 2 3 4 5 6 7 8 9 10 >
Munegowda Kc K Senior Research Fellow, Department of Microbiology, Melaka Manipal Medical College, - - 2014
Scrub typhus is an acute febrile illness caused by a tick bite infected with the bacteria Orientia tsutsugamushi. The clinical diagnosis is difficult as the symptoms are similar to other febrile illnesses such as dengue, typhoid, leptospirosis and so on. An eschar, if present, will narrow down the provisional diagnosis ...
Kakudo Kennichi K Department of Pathology, Nara Hospital Kinki University Faculty of Medicine, Ikoma 630-0293, - - 2014
The Japan Thyroid Association (JTA) recently published new guidelines for clinical management of thyroid nodules. This paper introduces their diagnostic system for reporting thyroid fine-needle aspiration cytology. There are two points where the new reporting system that differs from existing internationally-accepted ones. The first is the subclassification of the so-called ...
Palmer Elizabeth E HPV Research Group, Institute of Cancer and Genetics, School of Medicine, Cardiff University, - - 2014
The incidence of Human Papillomavirus (HPV)-associated tonsil cancer is increasing but the prevalence of HPV, and of premalignant precursors, in tonsil tissue is unknown. We aimed to assess prevalence of HPV infection in non-malignant tonsillar crypt epithelia and to histopathologically characterise positive samples. Formalin Fixed Paraffin Embedded (FFPE) tonsil tissue ...
Pedreira Renato do Prado Gomes RD Department of Clinic and Surgery, School of Dentistry, Federal University of Alfenas, Rua Gabriel Monteiro da Silva, 700, Alfenas, MG, CEP 37130-000, Brazil, - - 2014
Paracoccidioidomycosis is a disease that is endemic to southern and southeastern Brazil, caused by the fungus Paracoccidioides brasiliensis. The most common clinical oral manifestation is the presence of multiple granulomatous ulcers with hemorrhagic dots, located mainly on the lips, palate, and buccal mucosa. However, the disease can manifest atypically as ...
Tang Yee Lin YL Department of Pathology, Tan Tock Seng Hospital, - - 2014
We read with interest the recent paper of Hemminger and Iwenofu(1) on their experience with discovered on GIST1 (DOG1) antibody clone K9 on a range of mesenchymal and epithlelial lesions. Although this antibody is useful in confirming a diagnosis of GIST, we note that the antibody highlighted occasionally non-GIST mesenchymal ...
Inoue Seiya S Departments of Urology, Yonago Medical Center, Yonago, - - 2014
We describe a 49-year-old woman who presented with continuous bilateral lumbago. As the patient's ultrasonography manifestations were very similar to those of bilateral hydronephrosis, we performed retrograde pyelography and ureteroscopy. However, apart from slight left ureteropelvic junction obstruction, there was no hydronephrosis. Since malignant disease could not be completely denied, ...
Lowe Frazer J - - 2014
Atypical adenomatous hyperplasia (AAH) and squamous cell dysplasia (SCD) are associated with the development of malignant lesions in the lung. Accurate diagnosis of AAH and SCD could facilitate earlier clinical intervention and provide useful information for assessing lung cancer risk in human populations. Detection of AAH and SCD has been ...
Solsona Peiró Jordi J Unitat de Tuberculosi de Drassanes, Hospital Universitari Vall d'Hebron, Barcelona, España. Electronic address: - - 2014
This article analyzes the concept of inactive fibrotic lesions of presumed tuberculous origin (old healed tuberculosis), defined by radiological characteristics and a positive tuberculin skin test (TST), and we examine the evidence-based foundation for the indication of treatment of latent tuberculosis infection in these cases. We explore the risk of ...
Suárez-Alén Fátima F Stomatology Department, School of Dentistry, University of Santiago de Compostela, Santiago de Compostela, - - 2014
Present a case clinic of leimyosarcoma. Leiomyosarcomas (LMSs) are malignant mesenchymal tumours of smooth muscle differentiation that grow rapidly and whose prognosis is dependent upon the tumour site and disease stage. Their location in the oral cavity is considered extremely rare due to the lack of smooth muscle tissue in ...
Igari Kimihiro K Division of Vascular and Endovascular Surgery, Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: - - 2014
In this study, we evaluated the accuracy of the indocyanine green angiography (ICGA) test to diagnose peripheral arterial disease (PAD) with isolated infrapopliteal lesions. This study was undertaken from a retrospective review of PAD patients with isolated infrapopliteal lesions who underwent ICGA between November 2012 and July 2013. We calculated ...
Ting Tracy V TV Division of Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 4010, Cincinnati, OH 45229, USA. Electronic address: - - 2014
Cutaneous vasculitis in children is rare. Causes of cutaneous vasculitis are varied and are typically differentiated by the affected vessel size. A skin biopsy remains the gold standard for diagnosis but other causes for vasculitis, including systemic conditions, should be considered. This article discusses the childhood conditions commonly presenting with ...
Bizikova Petra P Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA; Center for Comparative Medicine and Translational Research, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, - - 2014
A recently launched topical ectoparasiticide containing fipronil, amitraz and S-methoprene has been associated with the development of an acantholytic pustular dermatitis similar to that of Promeris-triggered pemphigus foliaceus (PF). Our objectives were to describe the clinical, histological and immunological features of this PF-like cutaneous adverse drug reaction. Twenty-one dogs with ...
Loureiro Joana J From the Department of Pathology, Instituto Português de Oncologia, Porto, Portugal (Dr Loureiro); and the Department of Pathology, Massachusetts General Hospital, Boston (Dr - - 2014
Context.-Premalignant and malignant glandular lesions of the cervix are known to often cause diagnostic problems with a variety of benign (more common) as well as other malignant mimics, the latter setting often being represented by secondary involvement by endometrioid endometrial carcinoma especially in small samplings. Objective.-To highlight key histologic features ...
Shimamura Shunsuke S Division of Small Animal Internal Medicine (Shimamura, Kimura, Kobayashi, Sato, Yasuda) and Division of Small Animal Surgery (Kainuma, Okamura, Katayama), Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, - - 2014
A 13-year-old castrated male miniature dachshund dog was presented with chronic vomiting and diarrhea. Contrast radiography and surgical exploration revealed an ileal cyst, which was excised. A diagnosis of epidermoid cyst was made from a combination of the clinical findings and histological examination of the surgical specimen.
Neal Lonzetta L Division of General Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address: - - 2014
Imaging abnormalities detected by mammographic screening often lead to diagnostic evaluations, with suspicious abnormalities subjected to image-guided core needle biopsy (CNB) to exclude malignancy. Most CNBs reveal benign pathological alterations, termed benign breast disease (BBD). Adoption of CNB presents challenges with pathologic classification of breast abnormalities and management of patients ...
Adell Elisabet E Clinical Pathology, University and Regional Laboratories, Region Skåne, SUS Malmö, - - 2014
Cytology is central in the diagnosis of malignancy in effusions. Ancillary techniques, mainly immunocytochemistry, have considerably improved the sensitivity but some 10% of all cases remain equivocal and require the addition of new diagnostic modalities. We have previously shown that strong nuclear telomerase activity determined with Telomere Repeat Amplification Protocol ...
Schirru Enrico E aDepartment of Public Health, Clinical & Molecular Medicine, University of Cagliari, University Campus bUnit of Gastroenterology, Microcitemico Hospital, Cagliari cASL8 Cagliari, Blood Donation Center, Quartu Sant'Elena, - - 2014
New guidelines for celiac disease (CD) diagnosis from the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) propose the option to omit the duodenal biopsy in the diagnosis of CD. For this option, all four of the following criteria have to apply in children and adolescents: signs and symptoms ...
Eaton John E JE Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, - - 2014
Patients with primary sclerosing cholangitis (PSC) are at an increased risk for cholangiocarcinoma (CCA). Distinguishing benign from malignant biliary strictures with routine biliary cytology in this population is challenging. In this review, we examine the strengths and limitations of biliary cytology, review the application of other techniques to help minimize ...
Chen Zan Z Department of Neurosurgery, XuanWu Hospital, Capital Medical University, Beijing, - - 2014
Spinal extradural meningeal cyst (EMC) aetiology remains unclear. Based on our in-depth analysis of EMC clinical characters, we propose the alternative term 'dural dissection cyst' (DDC), which is more consistent with its aetiology and pathological manifestations. We examined the clinical, imaging and operative findings of four patients with spinal EMC ...
Yoshino Yusuke Y Department of Internal Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8606, - - 2014
We report a rare case of disseminated gonococcal infection in a 37-year-old man presenting with multifocal cellulitis. The patient presented with fever and painful swelling of the right foot and left hand, and was admitted to our hospital. CT scanning of the extremities revealed multifocal cellulitis. Transthoracic echocardiography findings were ...
Shield Paul W PW School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia; Department of Cytology, Sullivan Nicolaides Pathology, Taringa, Queensland, - - 2014
This study reviewed the clinical presentation, cytologic findings, and the immunophenotype of 69 Merkel cell carcinoma (MCC) cases sampled by fine-needle aspiration (FNA).  Demographic and clinical data, the cytology findings, and results of ancillary testing were reviewed.  Median patient age was 78 years (37-104) with a 1:1.8 female to male ...
Mlika Mona M a Department of Pathology , Abderrahman Mami Hospital , Tunis , - - 2014
The accurate diagnosis of lung carcinoma has become compulsory especially after the introduction of new target therapies. Most of the patients are non-operable. This fact points out the diagnostic importance of the cytology specimen. Our target was to assess the diagnostic efficacy of bronchial smears and cell blocks by comparing ...
Trimboli Pierpaolo - - 2014
The reported reliability of core needle biopsy (CNB) is high in assessing thyroid nodules after inconclusive fine-needle aspiration (FNA) attempts. However, first-line use of CNB for nodules considered at risk by ultrasonography (US) has yet to be studied. The aim of this study were: 1) to evaluate the potential merit ...
Lapa Constantin C From the Departments of *Nuclear Medicine, and †Surgery, ‡Institute of Radiology, and §Institute of Pathology, Universitätsklinikum Würzburg, Würzburg, - - 2014
Here we report on a 51-year-old man with the primary diagnosis of cholangiocarcinoma. Workup with CT and contrast-enhanced ultrasound revealed an additional lesion in the spleen, raising the concern for metastasis. Combined FDG PET/CT revealed a different metabolic pattern, making a metastasis unlikely. Histopathology of the splenic lesion confirmed sclerosing ...
Olmez Sehmus S Department of Gastroenterology, Medical Faculty,Yuzuncu Yil Universitesi, 65000, Van, Turkey, - - 2014
Diffuse nodular lymphoid hyperplasia (DNLH) of the intestine is an extremely rare lymphoproliferative disorder of uncertain etiology. Typically, numerous polypoid nodules composed of hyperplastic benign lymphoid tissue are present in the small and/or large intestinal mucosa. DNLH has been observed in association with common variable immunodeficiency (CVID). A 38-years-old man ...
Peng Tao T Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, - - 2014
To investigate the diagnostic value of Delta-like 1 ligand (DLL1) in cerebrospinal fluid (CSF) and serum, in tuberculous meningitis (TBM). Patients with a definite diagnosis of central nervous system infection (TBM, viral meningitis/encephalitis or bacterial meningitis) were prospectively enrolled alongside patients with intracranial metastatic tumour and patients with no diagnosis ...
Sayar Hamide H Department of Pathology, Kahramanmaraş Sütçü İmam University, Faculty of Medicine, KAHRAMANMARAŞ, - - 2014
Lymphangiomatous polyps of the palatine tonsils are uncommon hamartomatous proliferations that could be clinically misdiagnosed as malignant neoplasms. These polyps consist of dilated lymphatic vessels located inside fibrous and/or adipose tissue. In this paper, a 27-year-old man who presented to the outpatient clinic with a complaint of dysphagia is presented. ...
Kocbek Vida V Faculty of Medicine, Institute of Biochemistry , University of Ljubljana, Ljubljana , Slovenia - - 2014
Abstract In our previous low-density-array gene-expression analysis we found an increased expression of biglycan gene in ovarian endometriosis patients. In the present study we evaluated biglycan expression at the protein level in tissue, serum and peritoneal fluid (PF) from ovarian endometriosis patients, patients with benign ovarian cysts and healthy women. ...
Buinauskaite Evelina E Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, Medical Academy, Kaunas, - - 2014
Usually solar keratoses (SK) are diagnosed clinically. However other diseases may clinically present as erythematous macules, papules or patches on sun-exposed areas; therefore the histopathology remains the gold standard diagnostic tool. Our study, which assessed the efficacy of photodynamic therapy (PDT), showed that one in 20 clinically diagnosed SK lesions ...
Goyal Surbhi S Department of Pathology, University College of Medical Sciences, Dilshad Garden, Delhi, 110095, - - 2014
Palpable chest wall lesions are unusual manifestation of an underlying thoracic pathology and it is difficult to diagnose them with their diverse spectrum ranging from benign to malignant. Considering the exposure of patient to invasive biopsy/excision and the risk of local complications, FNAC is now being increasingly used in the ...
Berzina Inese I Preclinical Institute, Faculty of Veterinary Medicine, Latvia University of Agriculture, Jelgava, Latvia; Institute of Animal Pathology, Vetsuisse-Faculty, University of Bern, Bern, Switzerland. Electronic address: - - 2014
Canine granulocytic anaplasmosis (CGA) is caused by the rickettsial microorganism Anaplasma phagocytophilum. CGA is typically characterized by fever, thrombocytopenia, lethargy, anorexia, arthropy, and other nonspecific clinical signs. Skin lesions have been described in naturally infected lambs and humans. The pathophysiology of CGA is not entirely clear, and the persistence of ...
Jiang Kailun K Department of Ophthalmology, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada2Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa Hospital, The Ottawa Hospital, Ottawa, Ontario, Canada3Ottawa Hospital Research - - 2014
IMPORTANCE Immunohistochemical analyses may assist in the diagnosis of precancerous and cancerous conjunctival lesions. OBJECTIVE To use Vector Red (VR) to identify an immunologic marker that is sensitive for all melanocytes and another that is sensitive and specific for activated and/or atypical conjunctival melanocytic lesions (MLs). DESIGN, SETTING, AND PARTICIPANTS ...
Lai Marco M Transfusion Centre, Institute of Hematology, Catholic University, Rome, Italy, - - 2014
Previous investigations of the relationship between characteristics of immunoproteins on red blood cells (RBCs) and the occurrence of autoimmune haemolysis yielded divergent results. Here, we studied these characteristics in autoimmune haemolytic anaemias (AIHAs) to determine their relationship with the degree of anaemia at diagnosis. We studied at diagnosis 52 cases ...
Karakus Suleyman Cuneyt SC University of Gaziantep, Faculty of Medicine, Department of Pediatric Surgery Gaziantep, - - 2014
Intussusception is a common abdominal emergency in early childhood. The aim of this study is to describe the diseases mimicking intussusception and to discuss the causes and management of these conditions. Seven patients who were initially diagnosed as intussusception with abdominal ultrasonography but the final diagnosis were found as diseases ...
Kambouchner Marianne M Assistance Publique - Hôpitaux de Paris, Service d'Anatomie Pathologique, Hôpital Avicenne, Bobigny, - - 2014
Although histological NSIP is concisely defined, overlap with other patterns is described. Whilst most frequently idiopathic, NSIP is seen in various clinical contexts, as connective tissue diseases (CTDs) and chronic hypersensitivity pneumonitis (cHP). This study was designed to determine if NSIP could be separated into subgroups based on minor histological ...
Cheng Michelle Y MY University of Pittsburgh School of Medicine, Pittsburgh, - - 2014
The impact of having an established dermatologist on melanoma depth at diagnosis is incompletely understood. We sought to determine whether having had a previous dermatologic examination (an established dermatologist), the recency of the last examination, and the wait time for the dermatology appointment are associated with melanoma invasiveness and depth. This ...
Chaikhoutdinov Irina I Division of Otolaryngology-Head and Neck Surgery, Penn State Hershey Medical Center College of Medicine, Hershey, Pennsylvania, - - 2014
To examine patients with incidentally discovered thyroid nodules (IDTNs) with a focus on identification, evaluation, surgical intervention, and rates of malignancy. Case series with chart review. Tertiary care medical center. A total of 1408 patients were identified by cross-referencing thyroid diagnosis codes with ultrasound (US) codes between July 2008 and ...
Tidwell W James WJ University of Tennessee Graduate School of - - 2014
CD31 is a standard immunostain for evaluating vascular lesions of the skin, but CD31 reactivity for histiocytes is reported in only a small variety of pathological conditions. CD68 and CD163 are well recognized stains for cutaneous histiocytic lesions. We compared immunostaining of CD31 within that of CD68 and CD163 in ...
Lapa Constantin C Department of Nuclear Medicine, Universitätsklinikum Würzburg, - - 2014
A 72-year-old patient presented with drenching night sweats, weight loss, malaise as well as episodes of fever. Blood tests showed tricytopenia and elevated LDH levels (>900 U/l), all other values including comprehensive serology and screening for auto-immune antibodies were unremarkable. Ultrasonography revealed massive splenomegaly. Bone marrow biopsy of the posterior ...
Lee J W JW Otolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, South - - 2014
We describe a rare case of primary pharyngeal tuberculosis without pulmonary involvement in which the lesion was thought to be a submucosal tumour with overlying intact mucosa. A 58-year-old male attended the outpatient ward due to a globus sensation in the throat of 2-month duration. A swelling of the posterior ...
Schwock Joerg J Laboratory Medicine Program, University Health Network, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, - - 2014
Cavitating mesenteric lymph node syndrome (CMLNS) is an infrequently reported manifestation of unrecognized/longstanding celiac disease and may be associated with enteropathy-associated intestinal T-cell lymphoma and hyposplenism. Unrecognized malignancy and life-threatening infections can pose a significant risk to patients in cases of delayed diagnosis. Fine-needle aspiration of the mesenteric lesions may ...
Endo Hiroyasu H Department of Oral Diagnosis, Nihon University, School of Dentistry at Matsudo, - - 2014
Background: Desquamative gingivitis (DG) is a clinical manifestation common to several diseases. It is known that most cases of DG are caused by mucous membrane pemphigoid (MMP), oral lichen planus (OLP), or pemphigus vulgaris (PV). Early recognition and treatment of these diseases can improve the prognosis, but diagnostic delays are ...
El-Salhy Magdy M Department of Medicine, Section for Gastroenterology, Stord Hospital, Stord, - - 2014
The diagnosis of irritable bowel syndrome (IBS) remains a diagnosis of exclusion, whereby an extensive investigation is performed to exclude other organic diseases that may explain the symptoms of patients. Attempts to have a positive diagnosis based on symptom assessments failed to achieve widely use in clinical practice. Abnormalities in ...
Morales-Oyarvide Vicente V Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, - - 2014
Cystic pancreatic neuroendocrine tumors (cPanNETs) account for 13% to 17% of PanNETs. Although the value of endoscopic ultrasound (EUS) imaging and cyst fluid analysis (CFA) in their preoperative diagnosis has been well described, limited information is available about the diagnostic role of cytology samples obtained from fine-needle aspiration (FNA). Cytopathology ...
Sharma Virender K VK Arizona Digestive Health, 2680 South Val Vista, Suite 116, Gilbert, AZ 85295, USA. Electronic address: - - 2014
Endoscopy is commonly performed for the diagnosis and management of gastroesophageal reflux disease (GERD). Endoscopy allows the physician to evaluate esophageal mucosa for evidence of esophagitis and Barrett esophagus, to obtain mucosal biopsies for evaluation of such conditions as eosinophilic esophagitis and diagnosis and grading of Barrett esophagus, and to ...
Jacobs Eva E PhD Student, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The - - 2014
The formation of a fibroma of the tendon sheath, a rare, slow-growing, benign tumor, usually occurs in the upper extremities of young adult males. We present an extremely rare case of a fibroma of the tendon sheath arising adjacent to the Achilles tendon within Kager's triangle in a 41-year-old female. ...
Hartig Ingo I From the Departments of *Rheumatology and †Dermatology, Center of Inflammation Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Germany. The authors declare no conflict of - - 2014
Differential diagnosis of urticarial skin lesions not representing classic urticaria remains a challenge. Long-lasting nonpruritic urticarial plaques and the histopathologic finding of a dense infiltrate with neutrophil granulocytes are indicative for a rare entity within a group of diseases termed neutrophilic dermatoses.Here, we report a case of neutrophilic urticarial dermatosis ...
Zamani Adil - - 2014
Significant bleeding may occur following endobronchial forceps biopsy or brushing of necrotic or hypervascular tumors in the airways. In some cases, methods such as endobronchial instillation of iced saline lavage and epinephrine may fail to control bleeding. The present study evaluated the efficacy and safety of a new bronchoscopic technique ...
Batool Arooj A Department of Surgery, Benazir Bhutto Hospital, - - 2014
Choledochal cyst is an uncommon anomaly of the biliary system. It manifests by cystic dilation of the extra or intrahepatic biliary tract or both. Three cases of choledochal cysts are reported, who had presented with pain in right hypochondrium. All the three patients presented in one Surgical Unit of a ...
Park Sang Hyoung - - 2014
Appendiceal orifice inflammation (AOI) is a common 'skip lesion' in patients with ulcerative colitis (UC). However, other skip lesions are less well known. To evaluate the atypical distribution of UC lesions, other than AOI, in terms of their frequency, pattern, risk factors and prognostic implications. A retrospective analysis of colonoscopic ...
1 2 3 4 5 6 7 8 9 10 >