Search Results
Results 1 - 50 of 1203
1 2 3 4 5 6 7 8 9 10 >
Mori Ichiro I Department of Pathology, Mita Hospital, International University of Health and Welfare, Tokyo, - - 2014
In Japan, we have about 2000 board-certified pathologists. Most of them are working in the cities, thus few are available in the countries. Telepathology in Japan developed under these situations mainly to cover intra-operative frozen section diagnosis of rural hospitals. First, I would like to introduce telepathology network in Wakayama ...
Ganguly Akash A Warrington & Halton Hospitals NHS Foundation - - 2014
Objectives To perform a systematic review of ultrasound guided FNA services for head and neck lesions with assessment of inadequacy rates and related variables such as the presence of immediate cytological assessment. Methods A computer based systematic search of articles in English Language was performed using MEDLINE (1950 to date) ...
Bakry Ola Ahmed OA Department of Dermatology, Andrology and STDs, Faculty of Medicine, Menoufiya University , Shibeen El Koom , Egypt - - 2014
Abstract Nuclear factor kappa B (NFκB) is a key regulatory element in a variety of immune and inflammatory pathways, cellular proliferation, differentiation and apoptosis. Cyclo-oxygenase 2 (COX2) is one of the downstream targets of NFκB. The current work aimed to explore the possible role of NFκB and COX2 in psoriasis ...
Strazzula Lauren L UMass Memorial Healthcare, University of Massachusetts Medical School, Worcester, - - 2014
Pediatric fasciitides are rare benign lesions that may clinically mimic a malignant sarcoma. Nodular fasciitis, the most common of these fasciitides, rarely occurs in children younger than 5 years of age. Often there is a history of preceding trauma. Herein, we report the case of a 5-month-old boy diagnosed with ...
van der Marel J J Department of Research and Development, DDL Diagnostic Laboratory, Visseringlaan 25, 2288ER Rijswijk, The Netherlands. Electronic address: - - 2014
It has been suggested that colposcopy can miss a significant percentage of high-grade cervical intraepithelial neoplasia (CIN2+). Improved disease ascertainment was evaluated by taking multiple lesion-directed biopsies. In a cross-sectional multicentre study in the Netherlands and Spain, 610 women referred to colposcopy following abnormal cervical cytology results were included. Multiple ...
Eisenhofer Graeme G Institute of Clinical Chemistry & Laboratory Medicine, Technische Universität Dresden, Dresden, Germany; Department of Medicine III, Technische Universität Dresden, Dresden, - - 2014
We have noted the letter by Chortis et al.(1) published in response to our report about supine versus seated blood sampling for diagnosis of phaeochromocytoma.(2) There are several issues that the authors have missed and which they might wish to consider further in relation to their cost analysis and the methods ...
Kholová Ivana I Department of Pathology, Fimlab Laboratories, Tampere University Hospital, Tampere, - - 2014
Objective: The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) was introduced in thyroid cytology in 2007 and is now generally accepted. BSRTC categories include a morphologic description and risk of malignancy as well as follow-up suggestions in each group. However, the category entitled 'atypia of undetermined significance or follicular lesion ...
Rahangdale Lisa L Departments of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, N.C., - - 2014
Objective: It was the aim of this study to assess the utility of the manual liquid-based cytology (LBC) product VitroPrep™ Cytology Processing Kit (ChemQ Bioscience LLC, Research Triangle Park, N.C., USA). Study Design: This is a descriptive pilot study. Women underwent cervical sampling processed by the ThinPrep™ automated LBC system ...
Shah Rajal B RB Division of Urologic Pathology, Miraca Life Sciences Research Institute, Miraca Life Sciences, Irving 75039, TX. Electronic address: - - 2014
Accurate recognition of Gleason pattern 5 (GP5) prostate adenocarcinoma (PCa) on core biopsy (NBX) is critical because it is associated with disease progression and the worst clinical outcome. We evaluated 1557 consecutive and prospectively collected NBXs to determine the frequency of diagnosis, morphologic subpatterns, and their relation to the amount ...
Azad Aftab - - 2014
Clinical questionCan ultrasonography be used in lieu of chest radiography to diagnose pneumothorax?Articles chosen1. Ding W, Shen Y, Yang J, et al. Diagnosis of pneumothorax by radiography and ultrasonography: a meta-analysis. Chest 2011;140:859-66. [Epub 2011 May 5]2. Alrajhi K, Woo MY, Vaillancourt C. Test characteristics of ultrasonography for the detection ...
Hasanzadeh Malihe M Women Health Research center, Dept. of Gynecology Oncology, Mashhad University of Medical Sciences, Mashhad, - - 2014
Invasive squamous cell carcinoma of the vulva is primarily a disease of postmenopausal women and thus is rarely associated with pregnancy. We have reported on a young woman under 40 years old with vulvar carcinoma, which occurred during the pregnancy but optimal treatment was delayed to the postpartum period. This ...
Biolcati G - - 2013
Hailey-Hailey disease (HHD) is a rare, chronic and recurrent blistering disorder, which is characterized clinically by erosions occurring primarily in intertriginous regions, and histologically by suprabasal acantholysis. Oxidative stress plays a specific role in the pathogenesis of HHD, by regulating the expression of factors playing an important role in keratinocyte ...
Muizzuddin Neelam - - 2013
A major component to the etiology of acne is the growth and invasion by Propionibacterium acnes. Hydrogen peroxide is an excellent antimicrobial agent but is unstable in most formulations. We have developed a hydrogen peroxide generation system using the enzyme glucose oxidase and glucose. This system is stable in a ...
Bi Wenjing - - 2012
We report the uncommon case of a pericardial cyst with unremitting compression of the left ventricle during the whole cardiac cycle, but normal ejection fraction. On CT scan, the cyst was found at an atypical location, lateral to the pulmonary artery, the ascending aorta, and the right ventricular outflow tract ...
Vertemati Maurizio - - 2012
We generated a computerized morphometric model to evaluate and quantify the morphological features in large regenerative nodules (LRN), high-grade dysplastic nodules (HGDN) and hepatocellular carcinoma (HCC). Sixteen LRN, 10 HGDN and 16 HCC in HCV-cirrhotic livers were stained with H&E, smooth muscle actin, CD34, CD31 and reticulin to evaluate volume ...
Lalancette Cindy - - 2012
Cryptosporidium and Giardia (oo)cyst concentrations are frequently used for assessing drinking water safety. The widely used USEPA Method 1623 provides total counts of (oo)cysts, but may not be accurate for human health risk characterization, since it does not provide infectivity information. The total counts and infectious fraction of Cryptosporidium oocysts ...
Ben-Dor Itsik - - 2012
BACKGROUND: A fractional flow reserve (FFR) of <0.8 is currently used to guide revascularization in lesions with intermediate coronary stenosis. Whether there is an intravascular ultrasound (IVUS) measurement or a cutoff value that can reliably determine which of these intermediate lesions requires intervention is unclear. AIMS: We assessed IVUS measurement ...
Maeda Kengo - - 2011
Alexia with agraphia results from lesions of the left angular gyrus or the left posteroinferior temporal lobe. In Japanese or Korean persons, lesions of the latter cause alexia with agraphia for ideograms. We describe a case of alexia with agraphia for kanji (Japanese ideograms) caused by temporal lobe epilepsy. After ...
Simpkins Alexis - - 2011
Mycoplasma pneumoniae is a well-known cause of atypical pneumonia. CNS involvement is a relatively frequent extrapulmonary manifestation, most commonly manifesting as encephalitis in the pediatric population. We present two unusual cases of M. pneumoniae encephalitis that presented with symptoms and imaging findings suggesting mass occupying lesions, and worsening altered mental ...
Chiu Han-Mo - - 2011
Growing body of evidences have shown that narrow band imaging (NBI) can be the adjunct tool of colonoscopy for real time or optical histological assessment with high accuracy and largely replaces the role of chromoendoscopy. In spite of the advantages, there are still several issues that remain to be elucidated: ...
Bilgili Serap Gunes - - 2011
Pellagra is characterized by dermatitis, diarrhea, dementia and eventually death occurring as a result of niacin or its precursor tryptophan deficiency. Although pellagra is a well-known complication of isoniazid (INH) therapy, the clinical diagnosis may be missed or delayed that may cause life-threatening consequences. Due to the diversity of pellagra-related ...
Studer U - - 2011
Central nervous system involvement is a rare and serious complication of Behçet's disease (BD). Herein, we describe a patient with an atypical central lesion, who experienced progressive hypesthesia of the right arm and sensory loss of the trigeminal nerve together with intense headache. A repeated biopsy was necessary to conclusively ...
Patel Mrinali - - 2011
Uveal melanoma represents the most common primary intraocular malignancy in adults. Although uveal and cutaneous melanoma both arise from melanocytes, uveal melanoma is clinically and biologically distinct from its more common cutaneous counterpart. Metastasis occurs frequently in this disease, and, once distant spread occurs, outcomes are poor. No effective systemic ...
Incorvaia Cristoforo - - 2011
Diagnosis and treatment of hypersensitivity to Hymenoptera venom took a landmark step forward in the late 1970s with the introduction of venom as an adequate material instead of whole body extracts. Since then, venom immunotherapy (VIT) has provided allergic subjects with a complete protection from fatal anaphylaxis and prevented about ...
Donelson Ronald - - 2011
Despite its classic clinical presentation, and even when confirmed by compatible imaging findings of a herniated disc, the radiculopathy diagnosis provides only limited assistance for making decisions about treatment. The 2003 Medicare data revealed an eightfold variation in the rates of lumbar laminectomy and discectomy across geographic regions. In an ...
Held Laura - - 2011
Our understanding of oncogenetics and of the molecular mechanisms involved in melanoma development and signaling has dramatically changed in recent years. Today, melanomas are also classified based on molecular alterations. Emerging molecular therapies are targeted against specific mutations in melanoma. An example of targeted therapies is the successful treatment of ...
Kim Tae W - - 2011
Patients with malignant hyperthermia experience an exaggerated metabolic response when exposed to volatile anesthetic gases and succinylcholine. The minimum concentration of anesthetic gas needed to trigger a malignant hyperthermia crisis in humans is unknown and may remain so because of the inherent risks associated with studying the complex nature of ...
Anon Jack B - - 2011
Hereditary angioedema (HAE) is a relatively rare genetic disorder that is usually characterized by either low levels of C1 esterase inhibitor (C1-INH) or the presence of dysfunctional C1-INH. It can present with relatively mild and self-limiting symptoms, but it is also potentially fatal; the most common cause of death is ...
Sakurai Yasuhisa - - 2011
The author reviews the lesion localization of non-aphasic alexia and agraphia and proposes a new classification of alexia and agraphia on this basis. The newly proposed alexia and agraphia are pure alexia for kana (Japanese phonograms), or more generally pure alexia for letters, caused by a lesion in the posterior ...
Yamasaki Kouji - - 2011
A 51-year-old immunocompetent Japanese woman presented with a rare case of granulomatous amoebic encephalitis (GAE) caused by Balamuthia mandrillaris. She was brought to our hospital with epilepsy. Magnetic resonance imaging of the brain revealed a homogeneously enhanced solitary mass in the left frontal lobe. Histological diagnosis was made by a ...
Okazaki Kenichi - - 2010
We report the autopsy findings of a 63-year-old man with neurofibromatosis type 1 (NF1), in whom widespread ischemic brain lesions caused by vasculopathy associated with the disorder were observed. The patient, who had café au lait macules, axillary freckling, and neurofibromas, was inarticulate of speech, had difficulty in maintaining a ...
Baker K - - 2010
The differential diagnosis of large cystic brain lesions is wide. In the UK the most likely is tumour but infection should be considered. We present the case of a 47-year-old Indian man with such lesions and an unexpected pathological diagnosis. Mr S attended MAU in March 2008 with confusion, agitation ...
Petrovic Nebojsa S - - 2010
(i) To examine blood perfusion and metabolic activity of various brain tumours using radionuclide cerebral angiography (RCA) and single-photon emission tomography (SPET) after a single dose of Tc-methoxyisobutylisonitrile (MIBI). (ii) To examine if the inclusion of RCA can improve insight into the relative contribution of tumour perfusion to the uptake ...
Abdel-Aziz K - - 2010
A 51-year-old presented with subacute headache, right facial weakness and numbness. MRIB showed widespread enhancing hemispheric lesions with a focal lesion of the right CN VII nucleus. CSF protein 0.84 g/l; CSF lymphs 10×10(6)/l. A diagnosis of ADEM was made and symptoms resolved soon after steroids. Five months later, he ...
Elbers Jorina - - 2010
Primary angiitis of the central nervous system in childhood (cPACNS) is an immune-mediated inflammatory process directed toward blood vessels in the central nervous system. It has been associated with variable clinical and radiological presentations, and devastating consequences without treatment. Brain biopsy is required for definitive diagnosis. The objective of this ...
Pantazis G - - 2010
Herein, we report the case of a 72-year-old male with an exceedingly rare manifestation of a low-grade lymphoma in the brain associated with light chain deposition disease (LCDD). The patient presented with epileptic seizures. Magnetic resonance imaging (MRI) of the brain revealed multiple hyperintense lesions in the right parietal lobe ...
Jeynes Brian - - 2011
The pathogenesis of Alzheimer's disease (AD) senile plaque (SP) and neurofibrillary tangle (NFT) lesions putatively involves a compromised blood-brain barrier (BBB). P-glycoprotein (P-gp) is a recognized BBB-related efflux transporter protein. In this investigation we determined the density of SP and NFT lesions and capillary densities stained positively for P-glycoprotein (P-gp), ...
Petrelli Fausto - - 2010
A 57-year-old woman presented with metastatic renal cell carcinoma (RCC). She was enrolled in a clinical study, in which she received two cycles of neoadjuvant sunitinib therapy followed by cytoreductive nephrectomy. Her primary tumor and rib metastasis showed a good response to neoadjuvant therapy; however, after surgery, the patient developed ...
Wang Fei - - 2011
The purpose of this study was to explore brain MRI findings in neuromyelitis optica (NMO) and to investigate specific brain lesions with respect to the localization of aquaporin-4 (AQP-4). Forty admitted patients (36 women) who satisfied the 2006 criteria of Wingerchuk et al. for NMO were included in this study. ...
Falsetti Paolo - - 2011
To illustrate the ultrasonographic (US) and power Doppler US (PDUS) features of neurogenic heterotopic ossification (NHO) in consecutive patients with severe acquired brain injury and to evaluate the role of bedside US in diagnosis of NHO. Ninety-two consecutive patients with severe acquired brain injury underwent clinical and laboratory screening for ...
Miranda Soares Priscila Bernardina - - 2010
Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. We report a 23 year-old black woman with a mass at paravertebral region of T3-T5, multiple lesions in vertebral bodies and expanding skull-brain ...
Haegelen C - - 2010
Biopsies of brain stem lesions are useful for histopathological analysis, which guide appropriate treatment. The frame-based stereotactic procedure is the gold standard technique for biopsies of the brain stem. For the past few years, a frameless stereotactic robot, the NeuroMate robot (Renishaw, UK) has also been used for brain biopsies. ...
Schuette Albert J AJ Department of Neurological Surgery, Emory University, Atlanta, GA, USA. - - 2010
Patients with acute to subacute neurologic decline undergo a battery of imaging and laboratory tests to determine a diagnosis and treatment plan. Often, after an extensive evaluation, a brain biopsy is recommended as yet another tool to assist in determining the diagnosis. The goal of this retrospective cohort analysis is ...
Galgut Bradley I - - 2010
A 9-year-old female spayed Shetland Sheepdog was presented to the Kansas State University Veterinary Medical Teaching Hospital for evaluation following a 3-week history of left rear limb lameness that had progressed to generalized ataxia. Multifocal or diffuse brain lesions were suspected based on physical examination findings. Cerebrospinal fluid (CSF) contained ...
Rossi Rosario - - 2010
We report the clinical, EEG and neuroradiologic findings from three adult patients who developed new-onset seizure disorders as early clinical manifestations of de novo high grade glioma. The malignancies could not be recognised at the time of the first epileptic seizure because of minimal non-specific brain abnormalities, which showed no ...
Trocello J M - - 2011
Introduction Wilson's disease (WD) with neurological presentation is associated with brain lesions classically localised in globus pallidus, putamen, thalamus, mesencephalon, pons and dentate nucleus. Lesions of corpus callosum (CC) have not been studied in a broad population of patients with WD. Objective Evaluation of the frequency of CC lesions in ...
Foreid H - - 2010
Intracerebral amyloidoma (ICA) is a type of monoclonal immunoglobulin deposition disease (MIDD) which is accompanied by an overexpression and fibrillary assembly of monoclonal light chains, ultimately leading to nodular deposits of light chains in the form of amyloid light chain (AL-amyloid). The diagnosis is made by the histological demonstration of ...
Salunke Pravin - - 2010
Multicentric Gliomas, both supratentorial and infratentorial, with varying histopathological picture is extremely rare. We report a unique occurrence of such a combination in a 50-year-old man who presented with features of elevated intracranial pressure, ataxia and vertigo. Magnetic resonance imaging showed a diffuse non-enhancing lesion in the temporal lobe and ...
Chard Declan T - - 2010
PURPOSE: To develop an automated lesion-filling technique (LEAP; LEsion Automated Preprocessing) that would reduce lesion-associated brain tissue segmentation bias (which is known to affect automated brain gray [GM] and white matter [WM] tissue segmentations in people who have multiple sclerosis), and a WM lesion simulation tool with which to test ...
Umredkar Alok - - 2010
Cystic lesions of the brain may present with seizures or headache due to raised intracranial pressure. These cysts when associated with developmental brain anomalies may turn out to be pathologic surprises. In the present communication, two patients with glio-ependymal cysts were described with contrasting symptomatologies and surgical management. Non-enhancing cystic ...
1 2 3 4 5 6 7 8 9 10 >