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Stamelou Maria M Second Department of Neurology, Attiko Hospital, University of Athens, Rimini 1, Athens 12462, Greece; Department of Neurology, Philipps Universität, Baldingerstrasse, Marburg 35039, Germany; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK. Electronic address: - - 2015
Atypical parkinsonism comprises typically progressive supranuclear palsy, corticobasal degeneration, and mutilple system atrophy, which are distinct pathologic entities; despite ongoing research, their cause and pathophysiology are still unknown, and there are no biomarkers or effective treatments available. The expanding phenotypic spectrum of these disorders as well as the expanding pathologic ...
Clarindo Marcos Vinícius MV West Paraná State University, Cascavel, PR, - - 2014
Researches on DH have shown that it is not just a bullous skin disease, but a cutaneous-intestinal disorder caused by hypersensitivity to gluten. Exposure to gluten is the starting point of an inflammatory cascade capable of forming autoantibodies that are brought to the skin, where they are deposited, culminating in ...
Mukae Nobutaka N Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
"Solitary" meningioangiomatosis (MA) is a rare, benign, hamartomatous lesion of the cerebral cortex and frequently leads to epilepsy. However, the source of the epileptogenicity in meningioangiomatosis remains controversial. We report two surgically-treated meningioangiomatosis cases with medically intractable epilepsy. In both cases, chronic subdural electrocorticogram (ECoG) recordings identified the ictal onset ...
De Andrés Ana A Department of Immunology, Hospital Universitario Ramón y Cajal de Madrid, Carretera de Colmenar km 9100, 28034, Madrid, Spain, - - 2014
After clinical screening and the serological test, many patients still require a duodenal biopsy for celiac disease diagnosis. Mild histological lesions, unspecific findings and patchiness are frequent outcomes of this mandatory diagnostic tool, thus complicating clinical decisions. We analyzed the lymphoid components [number of total intraepithelial lymphocytes (IELs), TcR-γδ and ...
Carvalho Vânia Oliveira VO Division of Pediatric Dermatology, Department of Pediatrics, Federal University of Paraná, Hospital de Clínicas da UFPR, Curitiba, Paraná, - - 2014
Diaper dermatitis is a common cutaneous disorder of infancy, and diverse dermatoses may affect this region. To perform a differential diagnosis can be challenging. We present four cases to emphasise the importance of clinical diagnosis.
Wold Lindsey L Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL, 60064, USA, - - 2014
Hand dermatitis is a common skin complaint. We use our hands to explore our environment; subsequently, our hands are in frequent contact with potential allergens and irritants. Patients with hand dermatitis may present to their allergist with this complaint. Approaching the diagnosis and treatment of hand dermatitis can be challenging, ...
Contestable James J JJ Department of Dermatology, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD, 20889-5600, USA, - - 2014
Bullous systemic lupus erythematosus (BSLE) is a rare cutaneous complication of systemic lupus erythematosus (SLE). It is a heterogeneous disease that is caused by autoantibodies to the dermoepidermal junction, mainly type VII collagen. Similarities in histology and immunopathology exist between BSLE and other primary bullous dermatoses, namely dermatitis herpetiformis (DH) ...
Jin Bo B Epilepsy Center, Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, - - 2014
This study aimed to determine the accuracy of seizure diagnosis by semiological analysis and to assess the factors that affect diagnostic reliability. A total of 150 video clips of seizures from 50 patients (each with three seizures of the same type) were observed by eight epileptologists, 12 neurologists, and 20 ...
Karterud Hilde Nordahl HN National Centre for Epilepsy, Division of Neuroscience, Oslo University Hospital, Norway; Department of General Practice, Institute of Health and Society, University of Oslo, Norway. Electronic address: - - 2014
This qualitative study explored the impact of using a biopsychosocial approach to explain the diagnosis of non-epileptic seizures (NES). Semi-structured interviews of eleven adolescents and young adults who had participated in an inpatient follow-up stay of the diagnosis were used. The interviews were taped, transcribed, and analysed using systematic text ...
Singhi Pratibha P Department of Pediatric Neurology and Neurodevelopment, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India, - - 2014
Neurocysticercosis is the commonest parasitic disease of the nervous system in humans, and constitutes a major public health problem for most of the developing world. The clinical manifestations of Neurocysticercosis (NCC) largely depend on number of lesions, site, and host immune response against the parasite. Diagnosis is mainly based upon ...
Alexander Hamish H BrizBrain and Spine and NEWRO Foundation, The Wesley Hospital, Evan Thomson Building, Suite 20, Level 10, Chasely Street, Auchenflower, Brisbane, QLD 4066, Australia. Electronic address: - - 2014
Dysembryoplastic neuroepithelial tumour (DNET) is a benign tumour characterised by cortical location and presentation with drug resistant partial seizures in children. Recently the potential for malignant transformation has been reported, however progression without malignant transformation remains rare. We report a case of clinical and radiologic progression of a DNET in ...
Gurrado Angela A Unit of Endocrine, Digestive and Emergency Surgery, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Policlinico, Piazza Giulio Cesare, 11, 70124, Bari, - - 2014
A 61-year old man with coeliac disease and chronic lack of appetite, malabsorption and weight loss, despite the gluten-free diet, was operated because of a sub-diaphragmatic free air due to a small-bowel pneumatosis cystoides intestinalis (PCI). The jejunum showed granulomatous lesions with a honeycombed appearance of air cysts in the ...
Yang Andrew I AI Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, - - 2014
Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour-associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra- and supra-tentorial locations, in a 23-year-old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The ...
Taillibert Sophie S Pitié-Salpétrière Hospital, Neurology Mazarin and Radiation Oncology Departments, Paris, - - 2014
Cysts and cystic-appearing intracranial lesions are common findings with routine cerebral imaging examination. These lesions often represent a challenge in diagnosis. Intracranial cystic lesions have wide pathologic and imaging spectra, of which some require an aggressive and tailored treatment, whereas many others remain asymptomatic and do not require follow-up or ...
Wall Eric J EJ Divisions of *Orthopaedic Surgery #Sports Medicine, Cincinnati Children's Hospital, Cincinnati, OH †Department of Orthopedic Surgery, Division of Sports Medicine, Boston Children's Hospital, Boston, MA ‡St. Luke's Intermountain Orthopaedics, Boise, ID §Division of Orthopaedic Surgery, Rady Children's Hospital, San Diego, CA ∥Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO ¶Tennessee Orthopaedic Alliance, Nashville, - - 2014
The trochlear groove is the rarest location for osteochondritis dissecans (OCD) of the knee, with only about 50 previously reported cases, most of which were treated before the advent of magnetic resonance imaging (MRI) and modern techniques of cartilage fixation or osteochondral transplantation. The purpose of this multicenter study was ...
Wang Yong-Peng YP Department of Colorectal Surgery, The Liaoning Provincial Tumor Hospital, Shenyang, Liaoning 110042, P.R. - - 2014
Synchronous or metachronous occurrence of gastrointestinal stromal tumors (GISTs) and other primary gastrointestinal neoplasms has previously been reported. However, to the best of our knowledge, there are few studies regarding metachronous multiple GISTs and adenocarcinoma of the colon. The current case of an 80-year-old male patient who underwent a laparoscopic ...
Bourgeois Blaise F D BF Harvard Medical School, Children's Hospital, Boston, Massachusetts, - - 2014
Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy that shares many features and characteristics of other treatment-resistant childhood epilepsies. Accurate and early diagnosis is essential to both prognosis and overall patient management. However, accurate diagnosis of LGS can be clinically challenging. This article summarizes key characteristics of LGS and areas ...
Armaşu M M University of Agricultural Sciences and Veterinary Medicine of Iaşi, - - 2014
Links between deficits identified on neurological examination, age of seizure onset and the presence of structural forebrain disease have often been postulated in dogs presenting with a history of seizures. The purpose of this study was to assess the influence of such factors on the likelihood of structural or functional ...
Somma Francesco F Dipartimento medico chirurgico di Internistica Clinica e Sperimentale "Magrasi e Lanzara"-Sezione di Diagnostica per Immagini, Seconda Università di Napoli, Piazza Miraglia 2, 80138, Naples, Italy, - - 2014
Intestinal intussusception in adults is a rare condition, accounting for about 0.003-0.02 % of all hospital admissions. This condition in adults represents only 5 % of all cases of intussusceptions and is different from paediatric intussusception, which is usually idiopathic. In contrast, almost 90 % of cases in adults are secondary to various ...
Ikematsu Hiroaki H Department of Gastrointestinal Oncology & Endoscopy, National Cancer Center Hospital East, Kashiwanoha 6-5-1, Kashiwa, Chiba, 277-8577, Japan, - - 2014
Many authors have already reported the usefulness of narrow-band imaging (NBI) for the differential diagnosis of non-neoplastic and neoplastic colorectal lesions. However, it is not clear whether magnification is required for differential diagnosis. The aim of this prospective study was to clarify the clinical usefulness of a newly developed NBI ...
Teshima Christopher W CW Christopher W Teshima, Gurpal S Sandha, Division of Gastroenterology, University of Alberta, Edmonton, Alberta T6G 2X8, - - 2014
Endoscopic ultrasound (EUS) is an important part of modern gastrointestinal endoscopy and now has an integral role in the diagnostic evaluation of pancreatic diseases. Furthermore, as EUS technology has advanced, it has increasingly become a therapeutic procedure, and the prospect of multiple applications of interventional EUS for the pancreas is ...
Göya Cemil C Department of Radiology, Dicle University, School of Medical Science, Diyarbakir, - - 2014
The purpose of this preliminary study was to prospectively evaluate the diagnostic performance of acoustic radiation force impulse (ARFI) imaging for differentiating benign lesions from malignant renal tumours. Sixty patients with renal lesions were enrolled in the study; mean patient age was 49.52 ± 20.46 years (range 1-83 years) and patients included 30 men ...
Messadi Diana V DV Section of Oral Medicine and Orofacial Pain, Division of Oral Biology and Medicine, School of Dentistry, University of California at Los Angeles, Los Angeles, - - 2014
Optical spectroscopy devices are being developed and tested for the screening and diagnosis of oral precancer and cancer lesions. This study reports a device that uses white light for detection of suspicious lesions and green-amber light at 545 nm that detect tissue vascularity on patients with several suspicious oral lesions. The ...
Kurahashi Naoko N Department of Pediatric Neurology, Central Hospital, Aichi Human Service Center, Kasugai, Aichi, Japan. Electronic address: - - 2014
We aimed to assess the characteristics of thalamic lesions in children with acute encephalopathy with biphasic seizures and late reduced diffusion. Using the Tokai Pediatric Neurology Society database, we identified and enrolled 18 children with acute encephalopathy with biphasic seizures and late reduced diffusion from 2008 to 2010. Using diffusion-weighted ...
Hernández-Ibáñez C C Servicio de Dermatología, Hospital Costa del Sol, Marbella, España. Electronic address: - - 2014
Accurate subtyping of basal cell carcinoma (BCC) is crucial for the effective management of this disease and it is particularly important to distinguish between aggressive and nonaggressive histologic variants. Histologic subtype is not always accurately identified by biopsy and this can have serious implications. High-resolution ultrasound (HRUS) is a recent ...
Yamaguchi Rin R Department of Pathology and Laboratory Medicine, Kurume University Medical Center, Kurume, Japan; Department of Pathology, Kurume University School of Medicine, Kurume, - - 2014
To assess the diagnostic accuracy and outcome of breast papillary lesions diagnosed by ultrasound-guided core needle biopsy (CB) or vacuum-assisted "mammotome" biopsy (MT), and whether no surgical excision is justified in non-malignant papillary lesions so diagnosed. Among totally 3219 (MT2195/CB1024, respectively) breast biopsies spanning 5 years, 185 (5.7%) papillary lesions ...
Jiang Jue J Department of Ultrasound, Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, - - 2014
The purpose of this study was to retrospectively evaluate contrast-enhanced sonography for differentiation of benign and malignant thyroid nodules by analyzing the correlation between maximum intensity and microvessel density. From February 2010 to May 2012, 122 patients (85 female and 37 male; mean age ± SD, 45 ± 9.1 years) ...
Baba Youichirou Y Department of Pathology, JA Suzuka General - - 2014
A 45-year-old woman with persistent abdominal pain was admitted to our hospital. Detailed examination revealed a type 4 lesion with circumferential narrowing, which was diagnosed as a poorly differentiated carcinoma following forceps biopsy and ascitic fluid cytology. Although the lesion was surgically resected, the ascites increased rapidly, and her general ...
Gabbay Larissa Barcessat LB Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, SP, - - 2014
Histiocytosis is a systemic disease that usually affects the central nervous system. The aim of this study is to discuss the neuroimaging characteristics of Langerhans cell histiocytosis (LCH), the most common of these diseases; and the non-Langerhans cells histiocytosis (NLCH), which includes entities such as hemophagocytic syndrome, Erdheim-Chester and Rosai-Dorfman ...
Chronopoulos Argyrios A Depatment of Ophthalmology, Charité University Medicine Berlin, Berlin, Germany Institute for Pathology, Charité University Medicine Berlin, Berlin, - - 2014
The aim of this retrospective report is to describe our experience with the Essen-23G biopsy forceps (Akgül forceps) for biopsies of pigmented iris tumours. In this retrospective study of cases between October 2012 and September 2013, patients with iris tumours and clinical signs for malignancy underwent biopsy to secure the ...
Somigliana Edgardo E Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: - - 2014
There is consistent evidence demonstrating that laparoscopic removal of benign ovarian cysts significantly damages the ovarian reserve. In contrast, the pre-operative impact of these cysts on the ovarian reserve is yet controversial. To elucidate this aspect, we set up a cross-sectional study in reproductive age women with and without benign ...
Clevenger Jessica J Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, - - 2014
Accurate fine-needle aspiration (FNA) diagnosis of metastatic melanoma is of therapeutic and prognostic significance and often requires ancillary studies. To the authors' knowledge, the reliability of immunostaining using a pan-melanoma cocktail, Sry-related HMG-BOX gene 10 (SOX10), and microphthalmia transcription factor (MITF) in confirming a diagnosis of melanoma on FNA smears ...
Zandieh Shahin S Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Teaching Hospital of Medical University of Vienna, Austria - - 2014
The literature is sparse concerning 18F-fluorodeoxyglucose (18F-FDG) accumulation in the Hürthle cell neoplasm (HCN) of the thyroid. Given the difficulty of accurately diagnosing HCN, even with ultrasound (US) and fine needle aspiration biopsy (FNAB), the ability to accurately characterize these lesions by 18F-FDG positron emission tomography (PET) would be of ...
Kołodziejczak M M Department of General Surgery, Sub-Department of Proctology, Hospital at Solec, 00-382, Warsaw, - - 2014
The presence of endometriosis in the anal canal and perianal tissues is rare and difficult to suspect at clinical examination. We report our experience with preoperative ultrasound evaluation of four cases of anal endometriosis. Four patients were evaluated by transperineal and high-resolution three-dimensional endoanal ultrasonography. In 3 of 4 women, ...
Work Thierry M TM U. S. Geological Survey, National Wildlife Health Center, Honolulu Field Station, PO Box 50187, Honolulu, HI 96850, USA. Electronic address: - - 2014
We surveyed the reefs of Grande Terre, New Caledonia, for coral diseases in 2010 and 2013. Lesions encountered in hard and soft corals were systematically described at the gross and microscopic level. We sampled paired and normal tissues from 101 and 65 colonies in 2010 and 2013, respectively, comprising 51 ...
Heller Debra S DS 1Department of Pathology & Laboratory Medicine, Rutgers-New Jersey Medical School, Newark, NJ; and 2Department of Pathology, Duke University Medical Center, Durham, - - 2014
Most lesions of the Bartholin gland are cysts or abscesses. Clinicians are taught that lesions of the Bartholin gland occurring in older women should raise the differential diagnosis of malignancy, although these are uncommon. A variety of more unusual and rare lesions of the Bartholin gland have been reported. This ...
Rossetto André Luiz AL Department of Dermatology, University of Vale do Itajaí (Univali), Itajaí, SC, Brazil; Department of Pharmaceuticals-Biochemistry, University of Vale do Itajaí (Univali), Itajaí, SC, Brazil; Department of Dermatology, Botucatu School of Medical, Universidade Estadual Paulista "Júlio de Mesquita Filho"-São Paulo, State University (FMBUNESP), Vital Brazil Hospital, Butantan Institute, São Paulo, SP, Brazil - - 2014
A 7-year-old Caucasian female resident of the southern coast of Brazil presented dark spots on the left palm that converged to a unique macule with speckled pattern at about 1 month. The mycological exam and the fungi culture were typical of Hortaea werneckii, the agent of the superficial mycosis Tinea ...
Calvete Angela Cepero AC Departments of Radiology (A.C.C., J.D.B.M., E.S.M., B.T.S.) and Surgery (J.M.R.G., A.R.Z.), Virgen de la Arrixaca University Hospital, El Palmar, Murcia, Spain. - - 2014
To study acoustic radiation force impulse (ARFI) imaging as a new quantitative and noninvasive tool for evaluating thyroid nodules and to compare ARFI imaging with other tools for studying thyroid nodules: sonography, real-time elastography, and fine-needle aspiration biopsy. We conducted a prospective study from June 2011 to June 2012, which ...
Atarbashi Moghadam S S Dept of Oral & Maxillofacial Pathology, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Intraosseous mucoepidermoid carcinoma is a rare tumor which affects women more than men and is more common in the mandible. The radiological examination reveals a well-defined unilocular or multilocular radiolucent lesion. This tumor may resemble a glandular odontogenic cyst, particularly in incisional biopsies. The accurate diagnosis of these lesions is ...
Chavez Christine C 1 Respiratory Endoscopy Division, Department of Endoscopy, National Cancer Center Hospital, 5-1-1 Tsukiji Chuo-ku, Tokyo 104-0045, Japan ; 2 Department of Respiratory Medicine and Medical Oncology, Yokohama Municipal Citizen's Hospital, 56 Okazawa-Cho, Hodogaya-ku, Yokohama, Kanagawa 240-8555, Japan ; 3 Department of Pathology, National Cancer Center Hospital, 5-1-1 Tsukiji Chuo-ku, Tokyo 104-0045, - - 2014
Guided bronchoscopy has been found to be useful for the diagnosis of solid peripheral pulmonary lesions (PPLs) but more evidence on ground glass opacities (GGOs), especially those without a solid component, are lacking. A 69-year-old male, asymptomatic, heavy smoker was referred to our department for non-surgical diagnosis of a focal ...
Pichard Dominique C DC Department of Dermatology, Georgetown University Hospital, Washington, District of - - 2014
A 78-year-old Bulgarian woman presented to the National Institutes of Health (NIH) with a diagnosis of poorly differentiated metastatic carcinoma of unknown origin. The prior month she had been seen at a hospital in Bulgaria for weight loss and a right inguinal mass. NIH pathology review confirmed a poorly differentiated ...
Denison Amy M AM Division of High-Consequence Pathogens and Pathology, Infectious Diseases Pathology Branch - - 2014
 Rickettsia rickettsii, R. parkeri, and R. akari are the most common causes of spotted fever group rickettsioses indigenous to the United States. Infected patients characteristically present with a maculopapular rash, often accompanied by an inoculation eschar. Skin biopsy specimens are often obtained from these lesions for diagnostic evaluation. However, a ...
Akhter Shabnam - - 2014
A 45 year old woman underwent Laparoscopy-assisted total hysterectomy with staging procedure following a diagnosis of endometrial endometrioid adenocarcinoma on her endometrial biopsy. The hysterectomy specimen showed a FIGO I stage 1a, endometrioid carcinoma. A separate polypoid lesion in the endometrium, distinct from the carcinoma, was also identified. Microscopicopically the ...
Marx Sascha S Department of Neurosurgery, University of Greifswald, Sauerbruchstraße, Greifswald, - - 2014
Background and Importance Primary leptomeningeal melanoma (PLM) is highly malignant and exceedingly rare. Due to its rarity, diagnostic and treatment paradigms have been slow to evolve. We report the first case of a PLM that mimics a cervical spine meningioma and then discuss the current clinical, radiologic, and pathologic diagnostic methodologies ...
McKee Susan S Indiana University School of Medicine, Indianapolis, Ind., - - 2014
Objectives: The aim of this study is to determine the risk of neoplasm and malignancy in thyroid fine needle aspiration (FNA) diagnosed as atypia of undetermined significance with Hürthle cell change (AUS-H) or Hürthle cell neoplasm (HCN). Study Design: A computerized search of our laboratory information system was performed to ...
Chen Man M Department of Diagnostic Ultrasound, Zhong Shan Hospital, Fudan University School of Medicine, 180 Fen Lin Rd, 200032 Shanghai, China. - - 2014
Objectives- The purpose of this study was to differentiate perfusion and vascular characteristics between benign and malignant breast lesions by 3-dimensional contrast-enhanced sonography and evaluate their correlation with microvessel density and vascular endothelial growth factor (VEGF) expression for further clinical exploration. Methods- Three-dimensional contrast-enhanced sonography was performed in 183 patients ...
Taskin Umit U From the *Department of Otorhinolaryngology, Bagcilar Education and Research Hospital; and †Department of Radiology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, - - 2014
The malignant parotid lesions are fast growing and rapidly become symptomatic. Ultrasonography and fine needle aspiration biopsy are mainly used in the differential diagnosis of parotid lesions. The most common treatment of all parotid lesions is surgical excision. Here, we present a case of a very rapidly enlarging, painful parotid ...
Vanegas Edgar S ES Infectious Diseases Department, Instituto Nacional de Rehabilitación, Mexico City, - - 2014
Abstract. A 41-year-old woman had two months of intermittent migratory swellings in the trunk, face, and limbs associated with erythema, pruritus, and pain. Laboratory analysis showed moderate eosinophilia. The triad of eosinophilia, migratory lesions (nodular panniculitis), and raw fish consumption was highly suggestive of cutaneous gnathostomiasis. She was successfully treated ...
Pal Agnik A Post-Graduate Student, Department of Clinical and Experimental Pharmacology, School of Tropical Medicine , Kolkata, West Bengal, India - - 2014
Arsenic, an environmental toxin, significantly contributes to the development of several health problems. Epidemiological studies done across the globe have reported that a prolonged arsenic exposure has been associated with characteristic skin lesions, neuropathy and an increased risk of skin, lung, liver (angiosarcoma), bladder, kidney and colon cancers. In present ...
Germanakis Antonis A General Hospital of Agios Nikolaos, Agios Nikolaos, - - 2014
The main clinical signs and symptoms caused by a rickettsial infection typically begin 6-10 days after the bite and are accompanied by nonspecific findings such as fever, headache and muscle pain. The diagnosis is mainly based on serological tests, however antibody presentation may be delayed, at least at the early ...
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