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Siqueira Carla Silva - - 2014
Canalicular adenoma (CA) is an uncommon benign salivary gland tumor that mostly occurs in the upper lip. Despite its benign nature, some patients may present multiple nodules and also microscopic growth that can be multifocal with foci of tumor within the adjacent gland. Microscopically, CA can be mistaken for a ...
Waxman Sarah J SJ Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, - - 2014
To assess contamination of joints with tissue and hair debris after arthrocentesis. Experimental. Fetlock joint tissues (n = 6 horses). Soft tissue flaps including joint capsule were dissected from the dorsal aspect of fetlock joints of 6 anesthetized horses leaving an intact proximal base ("live" model) or with complete excision and immediate ...
Tirado Mariantonieta M Department of Dermatology, University of Münster, Münster, - - 2014
: Goltz-Gorlin syndrome presents with multiple basal cell carcinomas, odontogenic keratocysts, and cutaneous cysts, among other manifestations. The cutaneous cysts have been described as both epidermoid cysts and keratocysts but were not further characterized. Light microscopic examinations were made on 23 cutaneous cysts in 4 patients associated with Goltz-Gorlin syndrome ...
Sakamoto M M Department of Oral Diagnosis, Tohoku University Graduate School of Dentistry, Aoba-ku, Sendai, - - 2014
The purpose of this study was to clarify the diagnostic value of capsule-like rim enhancement (CLRE) on magnetic resonance imaging (MRI) for distinguishing malignant from benign tumours of the parotid gland. We retrospectively evaluated contrast-enhanced T1-weighted images of 100 patients with malignant and benign parotid tumours for the presence, completeness, ...
Latimer Elizabeth - - 2014
Neuroblastoma is the most common solid tumour of infancy and is responsible for 15% of childhood cancer deaths. Presence of amplified MYCN in neuroblastoma is associated with poor prognosis and rapid tumour progression. The aim of this study was to examine and compare the ultrastructural features of high-risk MYCN amplified ...
Mazza Joni M JM Department of Dermatology, St. Luke's-Roosevelt Center of the Icahn School of Medicine at Mount Sinai, New York, New York; Department of Dermatology, Beth Israel Medical Center, New York, New - - 2014
Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare, benign, congenital tumor of the dermis and subcutaneous tissue comprised of skeletal muscle and adipose and adnexal elements. Although the majority of cases are an incidental finding in otherwise healthy patients, some have been reported in association with other anomalies. We present a ...
Kikuchi Nobuyuki N Department of Dermatology, Fukushima Medical University, Fukushima, - - 2014
Typical skin rash, which appears and disappears along with respective rise and fall of fever, is well-known, and included as one of the major criteria of adult-onset Still's disease (AOSD) (Yamaguchi's criteria). In addition, various skin lesions are occasionally observed in association with AOSD. Persistent pruritic eruptions present with some ...
Machan Salma S *Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria; †Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain; and ‡Institute of Pathology, General Hospital of Leoben, - - 2014
: Follicular malignant melanoma (FMM) is a rare variant of melanoma arising on sun-damaged skin of elderly patients. It is characterized histopathologically by a prominent involvement of 1 or 2 adjacent hair follicles. The authors report 3 new cases of FMM (M:F = 2:1; age range, 23-67 years; median age, ...
Loynachan Alan T AT Veterinary Diagnostic Laboratory, College of Agriculture, University of Kentucky, Lexington, - - 2014
A 21-day-old Thoroughbred colt was euthanized following a history of recurrent colic. A 4.5 cm in diameter, occlusive, submucosal cyst was identified in the duodenum at necropsy. Histologically, the cyst was surrounded by a smooth muscle wall and was lined by both squamous and attenuated cuboidal to columnar epithelium. A ...
Rodrigues Luiz Oswaldo Carneiro LO Universidade Federal de Minas Gerais, Belo Horizonte, MG, - - 2014
Neurofibromatoses (NF) are a group of genetic multiple tumor growing predisposition diseases: neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH), which have in common the neural origin of tumors and cutaneous signs. They affect nearly 80 thousand of Brazilians. In recent years, the increased scientific knowledge on ...
Remmers G G Minnesota Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St Paul, MN, - - 2014
There are few reports of naturally occurring muscular dystrophy in domestic animals. Herein, we describe a case of muscular dystrophy in a 4-year-old neutered male American domestic shorthair cat that died unexpectedly following anesthesia for an elective surgical procedure. Macroscopic muscular hypertrophy and histologic evidence of myofiber size variation, mineralization, ...
Jo Vickie Y VY Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, - - 2014
Chordoma is a neoplasm of notochordal differentiation that typically occurs in the axial skeleton. Accurate diagnosis is therapeutically important but can be challenging, especially in fine-needle aspiration (FNA) and core needle biopsy (CNB). Immunohistochemistry for the transcription factor brachyury (T) has recently proven diagnostically useful in whole-tissue sections. Our aim ...
Langner Cord C Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036, Graz, Austria, - - 2014
Multilayered epithelium is defined as hybrid epithelium with characteristics of both squamous and columnar epithelia. Our aim was to evaluate the clinicopathological significance of the lesion by relating its presence to various histological and clinical and/or endoscopic features indicating gastroesophageal reflux disease (GERD). A total of 1,071 individuals participated in ...
Misago Noriyuki N Division of Dermatology, Faculty of Medicine, Saga University, Saga, - - 2014
Although the precise etiology of keratoacanthoma (KA) is unknown, KA is generally assumed to differentiate toward hair follicles based on previous studies of experimental carcinogenesis. We performed a comprehensive immunohistochemical study of various follicular markers in all stages of KA. A total of 67 tumors, including 16 early/proliferative stage lesions, ...
Ohfuji S S Department of Histopathology, Diagnostic Animal Pathology Office, Hokkaido, Japan. Electronic address: - - 2014
Epidermoid cysts were identified in the rumen of a 2-year-old Holstein-Friesian steer. Small nodules (<4 mm diameter) filled with paste-like, friable, white material were scattered in the rumen wall. Microscopically, the nodules were located in the submucosal connective tissue and comprised of cysts lined by stratified squamous epithelium surrounding keratin debris, ...
Eldaly Hasan H Aswan Eye and Laser Center , Aswan , Egypt - - 2014
Abstract Introduction: Optic nerve head (ONH) melanocytoma is a benign pigmented tumor that is detected as a dark brown mass on or adjacent to the optic disc. Ultrasonography, optical coherence tomography (OCT), and fundus fluorescein angiography (FFA) can be used to differentiate it from other pigmented tumor as well as ...
Campbell Robert N RN Joint Austin-Ludwig Oncology Unit, Level 4 Olivia Newton-John Cancer & Wellness Centre, Austin Hospital, 145 Studley Road, Heidelberg, VIC 3084, - - 2014
Granular cell astrocytoma (GCA) is an uncommon malignant glial tumour that is associated with a poor prognosis. GCA cells have some morphological and immunohistochemical similarities to macrophages. In this case, a small biopsy contained no typical astrocytoma and large rounded lesional cells were interpreted as negative for glial fibrillary acidic ...
Sarada P P Professor, Department of Pedodontics, Sri Sai College of Dental Surgery, , Vikarabad, Andhra Pradesh, India - - 2014
The solitary, nodular lesions of the oral mucosa present a diagnostic dilemma to the dentist with their analogous presentation. The lesions that appear on the tongue, a soft muscular organ are distinct and even rarer with varied manifestations. Oral mucosa presents lesions of the tongue in all age groups that ...
Jakobiec Frederick A FA Department of Ophthalmology, David G. Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts. Electronic address: - - 2014
A 46-year-old woman was evaluated for a "recurring papilloma" of the left medial upper eyelid margin. Beneath the papillary lesion medial to the punctum was a 5-mm diameter cutaneous mass thought to be cystic. After excisional biopsy, histopathologic analysis documented the presence of an epidermal keratinizing squamous papilloma surmounting a ...
Kodama Takahide T Centre for Inherited Cardiovascular Diseases, Transplant Research Area, Fondazione IRCCS Policlinico San Matteo, Viale Golgi 19, 27100, Pavia, Italy, - - 2014
No-reflow/slow-flow phenomenon (NF) is a poor prognostic factor in patients undergoing percutaneous coronary intervention. Distal protection devices (DPDs) prevent myocardial injury due to microembolic debris. When the target lesion involves a large side branch, DPDs can only protect the main vessel but not the side branch. In the present report, ...
Park Hai-Jin HJ *Department of Dermatology, Ilsan Paik Hospital, Inje University School of Medicine, Goyang, South Korea; †Department of Dermatology, University of Pennsylvania, Philadelphia, PA; and ‡Department of Pathology, Main Line Pathology Associates, Bryn Mawr Hospital, Bryn Mawr, - - 2014
: The term "induction" has been used to describe epidermal changes overlying a dermatofibroma (DF). Follicular induction is most often associated with DF, but can be observed in other lesions, including focal mucinosis, nevus sebaceous, seborrheic keratosis, wart, neurofibroma, and scars. Dermatofibrosarcoma protuberans (DFSP) is a malignant fibrohistiocytic tumor that ...
Alomari Ahmad I - - 2014
The diagnosis and management of vascular anomalies of the extremities can be challenging as these disorders are uncommon and may clinically overlap. The aim of this paper is to describe the clinical, radiologic, and histopathologic features of fibro-adipose vascular anomaly (FAVA), a previously unrecognized disorder of the limb. The clinical, ...
Conrad Rachel R From the Department of Pathology and Laboratory Medicine, Loma Linda University Medical Center, Loma Linda, - - 2014
Congenital granular cell epulis is a rarely reported lesion of unknown histogenesis with a strong predilection for the maxillary alveolar ridge of newborn girls. Microscopically, it demonstrates nests of polygonal cells with granular cytoplasm, a prominent capillary network, and attenuated overlying squamous epithelium. The lesion lacks immunoreactivity for S-100, laminin, ...
Levy Rebecca A RA Department of Pathology, Baylor University Medical Center at Dallas (Levy); Pathology Associates of Albuquerque, Albuquerque, New Mexico (Winham); the Department of Gynecologic Oncology, NEA Baptist Clinic, Jonesboro, Arkansas (Bryant); and the Department of Pathology, the University of Arkansas for Medical Sciences, Little Rock, Arkansas - - 2014
Smooth muscle neoplasms of the vulva can be mistaken for Bartholin duct cysts, which can lead to a delay in diagnosis. We present a case of vulvar leiomyoma and a case of leiomyosarcoma that clinically mimicked Bartholin duct cysts. Identification of leiomyosarcomas in this region is particularly important; due to ...
Ostri Christoffer C Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, - - 2014
We present a case of a patient with bilateral posterior ischaemic optic neuropathy in the previously unreported setting of hysterectomy indicated for severe postpartum haemorrhage. The diagnosis was based on clinical and paraclinical examinations, including MRI of the head, electroretinography (ERG) and visual evoked potentials (VEP) testing. During 1 year ...
Chandra Sunira S Department of Oral Medicine and Radiology, Saraswati Dental College and Hospital, Faizabad Road, Lucknow, India. - - 2014
Chronic ulcers of the oral mucosa are the lesions which a physician comes across frequently. "Eosinophilic Ulcer" is a rare variety of that. Eosinophilic ulcer or traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a chronic benign lesion of the oral mucosa and is a relatively recent delineated entity. Its ...
Mahajan Rashmi S RS Department of Dermatology, S.B.K.S Medical Institute and Research Centre, Piparia, Waghodia, Vadodara, Gujarat, - - 2014
An eccrine poroma is a solitary tumor arising from the eccrine duct epithelium in the epidermis. The lesions commonly occur on the sole of the foot, the hands, and occasionally on the nose, eyelids, neck, and chest. We report a patient who presented with a slow-growing nodular lesion over her ...
Mahesh Inbasekaran I Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, - - 2014
Spinal melanotic schwannomas are rare spinal tumours with a very poor prognosis in terms of mortality due to difficulty in complete resection and local recurrences. A 67-year-old man presented with acute onset progressive paraparesis for 2 weeks. The patient also had spotty skin pigmentations (blue naevi) in his right lateral ...
Bhaker Poonam P Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2014
Arachnoid proliferation, although rare, is known to occur in association with optic gliomas. However, chondroid and chordoid metaplasia has not been reported previously. A 27-year-old male presented with progressive, painless loss of vision in right eye, associated with vomiting and headache for one and a half months. Computed tomography (CT) ...
Huang Shih-Wei SW Department of Physical Medicine and Rehabilitation, Shuang Ho Hospital, Taiwan ; School of Medicine, College of Medicine, Taipei Medical University, Taipei, - - 2014
A 12 year old boy presented with ankle sprain. The physical examination revealed mild weakness of ankle dorsiflexion. An ultrasound was done for the soft tissues of the ankle. In addition to relative atrophy of the peroneus longus muscle, a compressive common peroneal nerve (CPN) lesion with a synovial cyst ...
Sinhasan Sankappa P SP Associate Professor, Department of Pathology, Indira Gandhi Medical College & Research Institute , Pondicherry, India - - 2014
The diagnosis of Nodular Fasciitis is a very challenging on cytological aspirations. Even in histopathological sections, it can be sometimes be mistaken for soft tissue sarcomas due to its high cellularity, presence of mitotic figures, poor circumscription and degenerative myxoid areas. Most commonly, nodular fasciitis is seen on extremities; and ...
Melikoglu Cenk C Plastic and Reconstructive Surgery, Sanliurfa Training Hospital, Sanliurfa, - - 2014
Introduction: Trichilemmal cysts (TCs) are common skin lesions that occur in hairy areas. A TC involving a fingertip has not been previously described in the literature. We herein report a case of a TC occupying a fingertip region. Case presentation: A 43-year-old woman presented with a 1.5 × 1.5 cm ...
Cohen Philip R PR Division of Dermatology, University of California San Diego, San Diego, California. - - 2014
Reticulohistiocytomas are benign dermal tumors that usually present as either solitary or multiple, cutaneous nodules. Reticulohistiocytosis can present as solitary or generalized skin tumors or cutaneous lesions with systemic involvement and are potentially associated with internal malignancy. A woman with a solitary red nodule on her knee is described in ...
Zheng Lijun L Department of General Surgery, Tenth People's Hospital of Shanghai, Tongji University, School of Medicine, Shanghai 200072, - - 2014
Schwannomas are tumors arising from the nervous system that also occur infrequently in the gastrointestinal tract, most commonly in the stomach. This report characterizes 29 patients with benign or malignant gastric schwannomas. Surgical data and clinical follow-up information were available for 28 cases with a median postoperative duration of 57 ...
Kaliyadan Feroze - - 2014
A 10-year-old boy presented to us with a localized patch of hair loss on the scalp, first noticed by his mother a few months after birth. The lesion had shown very little increase in size since that time. There was a history of occasional redness and discharge from the lesion, ...
Prze┼║dziecki R - - 2014
The presence of tumor within the serosal cavities, often connected with accumulation of serosal effusion, is a quite common problem in the small animal veterinary medicine. The first step in diagnosis of such cases is cytopathological examination. The aim of the present study was to evaluate the usefulness of cytology ...
Afroz Nishat N Department of Pathology, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, - - 2014
Giant cell fibroblastoma (GCF) is a rare soft tissue tumour that occurs almost exclusively in children younger than 10 years of age and is mostly located in the superficial soft tissues of the back and thighs. We present a rare case of GCF with encephalocele in a 1.5-year-old boy who ...
Mascitti Marco M Department of Clinic Specialistic and Odontostomatological Sciences, Polytechnic University of Marche, Ancona, - - 2014
The glandular odontogenic cyst (GOC) was a rare jawbone cyst described in 1988 as a distinct entity. This lesion can involve either jaw, and the anterior region of the mandible was the most commonly affected area. Clinical and radiographic findings were not specific, and the diagnosis of GOC can be ...
Rivero Elena Riet Correa ER Department of Pathology, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil. Electronic address: - - 2013
In most cases involving jaw lesions, a biopsy and a histopathological analysis are necessary to establish the final diagnosis. However, biopsy may be a complex procedure at some maxillomandibular sites, and some systemic conditions could contraindicate the procedure. Thus, a search for new, less invasive techniques, which could eventually replace ...
Agaimy Abbas A Institute of Pathology, University Hospital, Erlangen, Germany. Electronic address: - - 2013
Benign peripheral nerve sheath tumors (PNSTs) showing more than one line of differentiation (hybrid PNSTs) have been increasingly recognized, mainly due to awareness of their existence and as a consequence of increased use of immunohistochemisty during the last decade. Two recent studies suggested overrepresentation of hybrid tumors among benign PNSTs ...
Koba Shinichi S Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, - - 2013
We present a rare case of Merkel cell carcinoma (MCC) with heterologous differentiation. The patient was an 86-year-old female patient with MCC who presented with a forearm skin tumor and left axillary lymph node swelling. Histopathologically, the malignant components of the primary and metastatic lesions showed the intermingled features of ...
Sukkhojaiwaratkul Dabuswinee D Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, - - 2013
Epidermal nevus syndrome (ENS) is a rare congenital disorder. It is characterised by epidermal nevi and abnormalities of multiple organs, including central nervous system, skeleton, cardiovascular and genitourinary systems and eyes. Hypophosphatemic rickets-associated ENS has rarely been reported. We report a 46-month-old girl who presented with a classical feature of ...
Tay Joshua K JK Department of Otolaryngology - Head and Neck Surgery, National University Health System, Singapore. Electronic address: - - 2013
Pilomatricomas are benign skin tumors originating from hair matrix cells in the dermal layer of the skin, especially in the head and neck region. They may mimick malignant lesions on fine-needle aspirate cytology. This is a case report of a pilomatricoma of the cheek which was initially diagnosed as squamous ...
Kegler K K Department of Pathology, University of Veterinary Medicine, Bünteweg 17, D-30559 Hannover, - - 2013
Schwannomas arising in the parotid gland are rare in man and are not documented in domestic animals. This report describes the clinical, morphological and immunohistochemical findings of a benign schwannoma in the parotid gland of a 12-year-old warmblood gelding. A slow-growing mass was surgically excised from the parotid gland and ...
Luo Di-Qing DQ *Department of Dermatology, Huangpu Hospital of The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; †Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Departments of ‡Pathology, §Surgery, and ¶Anesthesiology, Huangpu Hospital of The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, - - 2013
: Eccrine nevus shows increase in number or size of eccrine glands, whereas hair follicle nevus is composed of densely packed normal vellus hairs, and eccrine-pilar angiomatous nevus reveals increase of eccrine, pilar, and angiomatous structures. No case with increased number of both eccrine glands and hair follicles only in ...
Kupferman Michael E ME Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: - - 2013
From 18% to 35% of cutaneous melanomas are located in the head and neck, and nearly 70% are thin (Breslow thickness ≤1mm). Sentinel lymph node biopsy (SLNB) has an established role in staging of intermediate-thickness melanomas, however its use in thin melanomas remains controversial. In this article, we review the ...
Sivolella Stefano - - 2013
To report a case of canalicular adenoma (CA) and discuss the use of immunohistochemistry to better address the diagnosis given some unusual characteristics in this patient. CA is an uncommon benign neoplasm that can develop in minor salivary gland duct tissues throughout the oral cavity. At histology, it shares several ...
Sakamoto Kei K Section of Oral Pathology, Tokyo Medical and Dental University, Tokyo, - - 2013
Peripheral odontogenic keratocyst (POKC) is a rare gingival cyst showing histologic features identical to those of keratocystic odontogenic tumor. A rare case of POKC associated with nevoid basal cell carcinoma syndrome (NBCCS) is presented. A 24-year-old woman with NBCCS presented with a pigmented papule, 3 mm in size, involving the ...
Xiao Ping - - 2013
Calcifying fibrous tumor (CFT) is a rare benign soft tissue tumor of unknown etiology and extremely rare in female reproductive system. We present a case of unusual CFT in the ampulla of fallopian tube occurring in a middle-aged female patient with multiple uterine leiomyomas. A hysterectomy was performed on a ...
Mostafa Mohamed G MG Department of Pathology, Assiut and Al-Azhar University Hospitals, Assiut University, Assiut, - - 2014
Melanocytes arise from the neural crest and migrate to the epidermis, meninges, uveal tract and ectodermal mucosa. Normal gastric mucosa lacks melanocytes. A 64-year-old woman presented to us with nausea and vomiting. She had a past history of invasive primary mucosal epithelioid malignant melanoma of the hard palate 21 months ...
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