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Kulbersh Brian D BD Pediatric ENT Associates, Children's of Alabama, Birmingham, AL, USA. Electronic address: - - 2015
This article explores pediatric lingual and other intraoral lesions. First the embryology and anatomy of the oral anatomy is outlined. Then the article discusses infections and inflammatory diseases, congenital malformations, benign neoplasms, and malignant tumors.
Hoff Stephen R SR Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, 675 N St Clair St, Chicago, IL 60611, USA; Division of Pediatric Otolaryngology-Head and Neck Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 East Chicago Avenue, Box 25, Chicago, IL 60611, USA. Electronic address: - - 2015
Vascular lesions of the head and neck are complex and diverse. These include infantile hemangioma, venous malformations, lymphatic malformations, and arteriovenous malformations, among others. Vascular malformations and tumors display different growth patterns and require different approaches to treatment. Therefore, accurate diagnosis is of utmost importance. This article is a guide ...
Vera-Sirera B B S de Anatomía Patológica, Hospital Universitario La Fe, Avda Campanar 21, 46009 - Valencia, - - 2014
Objetives: The aim of the present study was to analyze the expression levels of Cyclin D1 (CCD1), a nuclear protein that plays a crucial role in cell cycle progression, in a series of keratin-producing odontogenic cysts. Study Design: A total of 58 keratin-producing odontogenic cysts, diagnosed over ten years and ...
Turashvili Gulisa G Department of Pathology and Molecular Medicine, Queen`s University, Kingston, ON, Canada. Electronic address: - - 2014
The objective of this review was to discuss the highly variable terminology describing mucinous metaplasia of the endometrium, histologic features and characteristic findings by special stains and immunohistochemistry, differential diagnostic challenges, current treatment and prognosis. A review of the literature was performed on mucinous metaplasia of the endometrium. Mucinous metaplasia ...
Haddad Natalie N Universidade de Santo Amaro, Santo Amaro, SP, - - 2014
Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation. The most common form is a solitary lesion, but it can be multiple or ...
Wilkerson Myra L ML From the Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania (Drs Wilkerson, Lin, and - - 2014
Context .- Tumors of the genitourinary tract can be diagnostically challenging, particularly in core biopsies and cystoscopic biopsies with limited material. Immunohistochemistry is a valuable tool to use when morphology alone is insufficient for diagnosis. Objectives .- To review tumors and benign lesions of the kidney, urinary bladder, prostate gland, ...
Baghaei Fahimeh F Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, - - 2014
Statement of the Problem: Odontogenic cysts and tumors are the most frequent osseous destructive lesions of the jaws; however, there is little information regarding the relative frequency of these lesions among the Iranian population. Purpose: The purpose of this study was to determine the distribution of clinically and histologically- diagnosed ...
Khandakar Binny B Department of Pathology, NRS Medical College and Hospital, Kolkata, India. - - 2014
Ancient schwannoma is a rare variant of benign peripheral nerve sheath tumor, often morphologically mimicking malignancy. Retroperitoneum is an uncommon location. We describe one case of giant retroperitoneal ancient schwannoma. Literature concerning this variant is also reviewed. A 65 year old male presented with altered bowel habits. Imaging findings revealed ...
Wang Tingting - - 2014
Benign and malignant bone tumors can present similar imaging features. This study aims to evaluate the significance of apparent diffusion coefficients (ADC) in differentiating between benign and malignant bone tumors. A total of 187 patients with 198 bone masses underwent diffusion-weighted (DW) magnetic resonance (MR) imaging. The ADC values in ...
Livingstone E E Department of Dermatology and Skin Tumor Center, University Hospital Duisburg-Essen, Essen, - - 2014
Epidermal naevi (EN) are considered mosaic disorders. Postzygotic mutations are thought to occur during early embryogenesis. They are usually arranged along Blaschko's lines and tend to be noted either at birth or shortly thereafter. Skin tumors arising on EN were occasionally reported, with ongoing discussion whether these are collision tumors ...
Mittal Pardeep K PK Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1365 Clifton Road NE, Building A, Suite AT-627, Atlanta, GA, 30322, USA, - - 2014
Contrast-enhanced magnetic resonance imaging and magnetic resonance cholangiopancreatography (MRCP), due to their excellent soft tissue contrasts, have become first-line noninvasive tests in the characterization and detection of both hepatic and pancreaticobiliary pathologies. MRCP is also helpful in detecting the level and cause of obstruction in patients presenting with jaundice. Cholangiocarcinoma ...
Rosen Evan B EB Maxillofacial Prosthetics Fellow, Dental Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: - - 2014
Angiosarcomas are rare, malignant neoplasms of vascular origin that account for less than 1% of all soft tissue tumors. Angiosarcomas of the oral cavity are especially rare, and brachytherapy may be prescribed as a localized treatment to manage these malignancies. Intraoral brachytherapy requires collaboration between the radiation oncologist and a ...
Hunter Keith D KD Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield, S10 2TA, UK, - - 2014
The diagnosis of odontogenic tumors can be challenging, largely due to their rarity and consequent difficulties in gaining experience in their assessment. In most cases, careful attention to morphology, in conjunction with clinical and radiological features will allow a diagnosis to be made. However, in some cases, immunohistochemical analysis of ...
Hirshberg Abraham A Department of Oral Pathology and Oral Medicine, School of Dental Medicine, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, 69978, Tel Aviv, Israel, - - 2014
Metastatic dissemination to the oral cavity is rare and is usually the evidence of a wide spread disease with an average survival rate of 7 months. In almost a quarter of the cases, oral metastasis was found to be the first indication of an occult malignancy at a distant site. Metastatic ...
Zhu Hong-Xu HX Department of General Surgery, Zhongshan Hospital Fudan University, Shanghai 200032, - - 2014
Intrapancreatic accessory spleen is an uncommon congenital abnormality of the spleen with no indication for surgical intervention. Among the few cases reported, IPAS coexisted with a normal spleen. We here report the first case of IPAS arising a couple years after splenectomy with the appearance of an endocrine tumor of ...
Coloma-González I I Servicio de Párpados, Órbita y Vía Lagrimal, Asociación para evitar la Ceguera IAP, Hospital Dr. Luis Sánchez Bulnes, México DF, México. Electronic address: - - 2014
The case is presented of a 51 year-old woman with a firm mass at the medial canthus of the right eye of five years onset. A low-grade lymphoproliferative lesion (reactive lymphoid hyperplasia) was diagnosed from an excisional biopsy DISCUSSION: Lacrimal sac tumors are rare, with a peak incidence in the ...
Matos António P AP Department of Radiology, Hospital Garcia de Orta, Almada, Portugal; Department of Radiology, UZ Leuven, Luven, Belgium. Electronic address: - - 2014
We present a case of a primary cardiac lymphoma in a 60-year-old woman. The clinical presentation was non-specific and the diagnosis was suggested by its appearance on multidetector computed tomography. The final diagnosis was achieved by histopathological study and was corroborated by a decrease in tumor volume after targeted chemotherapy. ...
Longo C C Dermatology and Skin Cancer Unit, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, - - 2014
Nevoid melanoma (NeM), a rare variant of melanoma, can be difficult to detect since its clinical and histopathologic morphology can simulate a nevus. To describe the clinical and dermoscopic features associated with NeM. Lesions with histopathologic diagnosis of NeM were collected via an e-mail request sent to all members of ...
Nam Seung-Joo SJ Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Republic of - - 2015
Various cases of gastrointestinal stromal tumor (GIST) coinciding with other gastrointestinal malignancies have been reported to date, however, the synchronous occurrence of GIST and intrahepatic cholangiocarcinoma (ICC) is exceptionally rare and, to the best of our knowledge, has only been reported once. The coinciding malignancy has usually been encountered incidentally ...
Peng Xu Zhi XZ Department of Neurology, Wuhan General Hospital of Guangzhou Command, Wuhan, - - 2014
Tumor-like inflammatory demyelinating disease (TIDD) usually occurs in the brain and rarely occurs in the spinal cord. TIDD appears to be very similar to tumors such as gliomas on imaging, which may lead to incorrect or delayed diagnosis and treatment. Because of headache and incoherent speech, a 24-year-old Chinese male ...
Chang Sunhee S Department of Pathology, Inje University Ilsan Paik Hospital, Goyang, Republic of - - 2014
The differentiation of malignant mesotheliomas and benign mesothelial proliferations is crucial in determining patient care and prognosis. But, this distinction can be extremely difficult, particularly in small biopsies. Recently, insulin-like growth factor II mRNA-binding protein 3 (IMP3) and glucose transporter 1 (GLUT-1) have been reported as specific and sensitive markers ...
Fernandez-Flores Angel A Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, - - 2014
Several types of large atypical epithelioid cells can mimic tumoral melanocytes and can therefore be a source of misdiagnosis of melanoma. Megakaryocytes are one of these types, and are not frequently mentioned in the literature. In the current report, we present the case of a 76-year-old man presenting with acute ...
De Falco Alfano Daniele D Azienda Ospedaliera-Universitaria di Ferrara, Struttura Complessa di Radiologia Universitaria - Dipartimento di Diagnostica per Immagini e Medicina di Laboratorio, via Aldo Moro, 8, 44124 Ferrara, Italy. Electronic address: - - 2014
Hamartoma is the most common benign lesion of the lung, but endobronchial localisation is rare. Typically occurs between the fifth and seventh decade of life and in literature has never been described in association with pregnancy. We report the case of a young woman in whom the tumor seems to ...
Cinotti Elisa E Department of Dermatology, University Hospital of Saint-Etienne, Saint-Etienne, France. Electronic address: - - 2014
To evaluate whether the handheld in vivo reflectance confocal microscopy that has been recently developed for the study of skin tumors is suitable for the diagnosis of conjunctival tumors. Prospective study, observational case series. We prospectively evaluated the reflectance confocal microscopy features of 53 conjunctival lesions clinically suspicious for tumors of ...
Kimura Takashi - - 2014
Objectives: To consider the biologic behaviors of keratocystic odontogenic tumors (KCOTs) and ameloblastomas and dentigerous cysts. Methods: A 63-year-old Japanese man presented with swelling and discomfort in the left cheek during jaw movement. Examination revealed a multilocular lesion within the mandible extending from the left second premolar to the left ...
Piris Adriano A Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114; Department of Dermatology, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, MA 02114; Department of Pathology, Massachusetts General Hospital, Boston, MA - - 2014
BAP1 (BRCA1-associated protein 1) is a tumor suppressor gene whose mutations have recently been reported to increase susceptibility for the development of uveal melanoma, cutaneous atypical and epithelioid melanocytic lesions, clear cell renal cell carcinoma, and other tumors. Screening for BAP1 mutation/loss/inactivation and BRAFV600E mutation can be done by immunohistochemistry. ...
Hu Yuan-Yuan YY Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. - - 2014
Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic neoplasm of the jaw. AFS is characteristically composed of a benign odontogenic epithelium and a malignant mesenchymal component. The posterior region of the mandible is the predominantly occupied site. In the present report, a new case of AFS in a 22-year-old male ...
Pan Jiyong J Department of General Surgery, The Third People's Hospital of Dalian, Dalian, Liaoning 116000, P.R. - - 2014
Schwannomas are slow-growing mesenchymal neoplasms that arise from Schwann cells with low malignant potential. These uncommon neoplasms are nerve sheath tumors that arise at almost any anatomical site. The majority of schwannomas are benign, and few are malignant. The current study presents the rare case of an anal schwannoma that ...
Dong Jinghui J Medical Imaging Center, The 302nd Hospital, Beijing 100039, P.R. - - 2014
Malignant fibrous histiocytoma (MFH) is a tumor that occurs throughout the body as a relatively uncommon entity. The current study presents two cases of primary malignant fibrous histiocytoma of the liver. The first case was of a 67-year-old male who exhibited no symptoms or abnormal physical signs, and in whom ...
Sakurai Urara U *Department of Pathology, Tokyo Metropolitan Geriatric Hospital ∥Department of Surgery, Kudanzaka Hospital †Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan ‡Department of Pathology, Massachusetts General Hospital, Boston, MA §Institute of Pathology, Klinikum Bayreuth, Bayreuth, - - 2014
Gastric neoplasms classified as high-grade dysplasia (HGD) by Western pathologists are frequently diagnosed as tubular adenocarcinoma in Japan. Here, we evaluated the prevalence of submucosal and lymphovascular invasion in a series of 125 endoscopically resected gastric neoplasms. On the basis of Western criteria, the lesions were classified as poorly cohesive ...
Melamud Kira K From the Department of Radiology, Boston University Medical Center, 820 Harrison Ave, 3rd Floor, Boston, MA 02116 (K.M., D.H., F.W.R., A.G.); Department of Radiology, Cochin University Hospital, Paris, France (J.L.D.); Department of Radiology, Bridgeport Hospital, Yale University School of Medicine, Bridgeport, Conn (D.H.); Department of Radiology, Klinikum Augsburg, Augsburg, Germany (F.W.R.); and Department of Radiology, University of Erlangen, Erlangen, Germany (F.W.R., - - 2014
Primary lesions of the tubular bones of the digits are not uncommon, and the vast majority of these lesions are benign. Benign intramedullary lesions such as enchondromas are frequently discovered incidentally, unless they are associated with a pathologic fracture. Expansile lesions or lesions that are pedunculated and protrude from the ...
Shetty Archana A Departments of Pathology, Sapthagiri Institute of Medical Sciences and Research Center, Chikkasandra, Bangalore, Karnataka, - - 2014
Malignant melanoma poses a remarkable capacity for morphological diversity and often presents as a diagnostic challenge due to its wide clinical presentation. We present a case of a 73-year-old lady, with a large superficial ulcerative nodular mass on the flexor aspect of the right upper arm. On fine needle aspiration ...
Matsumoto Shinji S Department of Health Sciences, Faculty of Medical Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, - - 2014
Malignant pleural mesothelioma (MPM) is a neoplastic disease with a poor prognosis. The complete resection of tumor with extra-pleural pneumonectomy is effective only for early stage epithelioid-type MPM. An accurate pathological diagnosis including the histological subtype and also clinical staging are crucial to decide on the therapeutic approach. However, the ...
Yiu Z Z N ZZ The Dermatology Centre, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, Manchester M6 8HD, UK. Electronic address: - - 2014
Giant condylomata acuminata (GCA) is a rare, locally invasive tumour that may undergo malignant transformation. It was first described a HPV-induced penile tumour which clinically resembled both a squamous cell carcinoma and condyloma acuminatum, often arising from a pre-existing warty lesion. We describe a case of peri-stomal GCA transformation into ...
Honarpisheh Hedieh H Yale School of Medicine, Yale Dermatopathology, 15 York Street LMP 5031, New Haven, Connecticut, United States, 06520. - - 2014
Tumors with similar or identical histopathologic features have been termed basaloid follicular hamartoma (BFH) or infundibulocystic basal cell carcinoma (BCC). Basal cell carcinoma typically lacks immunoreactivity with cytokeratin 20 (CK20) and pleckstrin homology-like domain, family A, member 1 protein (PHLDA1). Aim We investigated a series of BFH and infundibulocystic BCC ...
Bakuła-Zalewska Elwira E Department of Pathology, The Maria Skłodowska-Curie Cancer Center and Institute of Oncology, Warsaw, - - 2014
Hyalinizing trabecular tumor (HTT) is a rare neoplasm which usually follows an indolent clinical course. The cytologic diagnosis of HTT can be challenging as these neoplasms share cytomorphological features with other thyroid neoplasms and paraganglioma. In fine-needle aspiration (FNA) smears a diagnosis of papillary thyroid carcinoma (PTC) or suspicion of ...
Sidhu Kiranjit K Department of Chest and tuberculosis, Guru Gobind Singh Medical College, Faridkot, India. - - 2014
Askin tumor is a rare malignant neoplasm of the chest wall. A 23 year old primigravida patient was admitted to the hospital with complaints of chest wall swelling, cough & dyspnea. Radiological examination showed a chest wall mass in right hemithorax with erosion of ribs and moderate pleural effusion. Fine ...
Jin Long L *Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN †Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, - - 2014
The diagnosis of malignant thyroid tumors in some cytologic and histologic specimens remains challenging. High-mobility group A2 (HMGA2) expression and insulin-like growth factor II mRNA-binding protein-3 (IMP3) expression were evaluated by relative quantitative reverse transcription-polymerase chain reaction (qRT-PCR). The aim of this study was to evaluate whether the combination of ...
Sukegawa Shintaro S Division of Oral and Maxillofacial Surgery, Kagawa Prefectural Central Hospital, Takamatsu, Kagawa 760-8557, - - 2015
Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare type of odontogenic carcinoma arising from the jawbone. Odontogenic cysts are true cysts that arise from the dental epithelium, which is associated with tooth formation. The epithelial lining of odontogenic cysts has the potential to transform into various types of odontogenic ...
Katsuno Hidetoshi H Department of Surgery, School of Medicine, Fujita Health University, Dengakugakubo 1-98, Kutsukake, Toyoake, Aichi, 470-1192, Japan, - - 2014
We report a case of gigantic cystic lymphangioma of the ascending colon excised through an open laparotomy. A 34-year-old woman consulted a gynecologist for treatment of infertility. Transvaginal ultrasonography revealed a cystic mass in the pelvis, and she was transferred to our hospital for further investigation. Abdominal enhanced computed tomography ...
Shen Cheng - - 2014
Cavernous hemangioma in the thymus is a rare presentation in mediastinal hemangiomas. The diagnosis is difficult to make promptly because both invasive and noninvasive examinations usually fail to distinguish it from other tumors of the mediastinum. Their clinical presentations depends on their size and their involvement with adjacent mediastinal structures. ...
Sheahan Patrick P Department of Otolaryngology, South Infirmary University Hospital, Cork, - - 2014
The follicular variant (FV) of papillary thyroid carcinoma (PTC) is an important subtype that can be difficult to diagnose using preoperative cytologic analysis. To compare conventional and FV PTC with regard to preoperative cytologic diagnosis using a tiered thyroid cytologic reporting system, tumor size at diagnosis, presence of invasion, and ...
Bajaj Jaya J Department of Pathology, North Shore-LIJ Health System, School of Medicine, Lake Success, N.Y., - - 2014
Background/Aim: The primary role of fine-needle aspiration cytology (FNAC) of salivary gland masses is to determine the underlying process and guide further management. The objective of our study is to provide a comprehensive review of cytologic features and ancillary studies of mammary analog secretory carcinoma (MASC), discuss differential diagnosis and ...
Parsai Arman A Barts Health NHS Trust. Electronic address: - - 2014
In 150 patients, 153 hepatic lesions (39 metastases, 27 hemangiomas, 26 hepatocellular carcinomas, 25 cysts, 15 adenomas, 8 focal nodular hyperplasias, 5 abscesses, 4 hamartomas, and 4 cholangiocarcinomas) were evaluated during a 24-month period. Apparent diffusion coefficient (ADC) values of benign lesions (1.994×10(-3)mm(2) s(-1)) were significantly higher than ADC values ...
Guo Shuangping S Department of Pathology, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shan Xi Province, 710032, China. Electronic address: - - 2014
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by multisystem infiltration by foamy histiocytes surrounded by fibrosis. ECD often involves the long bones, skin, and retroperitoneum, whereas breast involvement is very rare with only 6 reported cases in English literature. We report a case of ECD presenting within ...
Chi Angela C AC Division of Oral Pathology, College of Dental Medicine, Medical University of South Carolina, 173 Ashley Ave., Charleston, SC, 29425, USA, - - 2014
The purpose of this study is to evaluate surface papillary epithelial hyperplasia, a microscopic finding that corresponds to the clinical finding of rough or stippled mucosa, as a predictor of polymorphous low-grade adenocarcinoma (PLGA). We conducted a retrospective review of minor salivary gland neoplasms submitted to our biopsy service from ...
Malkoc Melih M Department of Orthopedics and Traumatology, Istanbul Medipol University, School of Medicine, Turkey. Electronic address: - - 2014
Nerve sheath myxomas (NSM) are rare benign soft tissue tumors. The dorsal paravertebral placed NMS diagnosis can be difficult. This article presents clinical, radiological findings and treatment of the NSM of the dorsal paravertebral space in a 32-year-old man presented with a right shoulder and back pain for 4 years. ...
Zhang Zhixu Z Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of - - 2014
The aim of this study was to investigate characteristic CT manifestations of the group of ovarian thecoma-fibroma. 24 patients (26 lesions) presenting with the ovarian thecoma-fibroma were analyzed retrospectively, and the diagnosis were confirmed by pathology after surgery. Our findings included: 22 patients were unilateral, while 2 were bilateral; 12 ...
Lombardi Davide D Department of Otorhinolaryngology, University of Brescia, Piazza Spedali Civili 1, 25100, Brescia, - - 2014
Merkel cell carcinoma is a neuroendocrine tumor that occurs predominantly on the sun-exposed skin, with rare cases in the extracutaneous sites. It represents one of the extremely rare malignant neuroendocrine tumors of the salivary glands. We report a case of primary Merkel cell carcinoma of the right submandibular gland. The ...
Morosi C C Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, - - 2014
Aim of study was to assess the correlation between computed tomography scan (CT) findings and histopathology. Data were collected on consecutive patients with suspected retroperitoneal sarcoma (RPS) referred to a tertiary sarcoma center. Patients underwent contrast enhanced multi-detector CT scans. Radiological features of lesions were classified according to the presence ...
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