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Freesmeyer Martin M Clinic of Nuclear Medicine, Jena University Hospital, Bachstraße 18, 07743, Jena, Germany, - - 2014
The role of (124)Iodine-PET/US Fusion technique is demonstrated in a 52-year-old woman with De Quervain's subacute thyroiditis. A small and adversely located lesion not detected by thyroid scintigraphy could be unambiguously matched with a hypofunctional PET finding. The presented case supports the clinical potential of PET/US Fusion technique in thyroid ...
Lin Martin Hsiu-Chu MH Department of Neurosurgery, Chung Gung Memorial Hospital , Chiayi , - - 2014
A 23-year-old male presented with a parasellar lesion which was suspected as disseminated intracranial germ cell tumour. The diagnosis of germinoma was made using immunohistochemistry from percutaneous trans-foramen ovale biopsy. This report describes the role of neuronavigation-guided biopsy through the foramen ovale for lesions in the parasellar region.
Antonescu Cristina R CR Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, - - 2014
Epithelioid hemangioma (EH) is a benign neoplasm with distinctive vasoformative features, which occasionally shows increased cellularity, cytologic atypia, and/or loco-regional aggressive growth, resulting in challenging differential diagnosis from malignant vascular neoplasms. Based on two intraosseous EH index cases with worrisome histologic features, such as the presence of necrosis, RNA sequencing ...
Choi Hwan Jun HJ From the Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University, Cheonan, - - 2014
Generally, dermoid and epidermoid cysts arise as a result of incomplete separation of the neuroectoderm from the superficial ectoderm with displacement of ectodermal elements along their lines of fusion during development. Dermoid cysts of the posterior head are rare lesions composed of epidermal and mesodermal elements. Furthermore, dermoid cysts in ...
Nakada Takeo T Department of Thoracic Surgical Oncology, Thoracic Center, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, - - 2014
Objectives: We aimed to identify high-resolution computed tomography (HRCT) features useful to distinguish the anaplastic lymphoma kinase gene (ALK) fusion-positive and negative lung adenocarcinomas.Methods: We included 236 surgically resected adenocarcinoma lesions, which included 27 consecutive ALK fusion-positive (AP) lesions, 115 epidermal growth factor receptor mutation-positive lesions, and 94 double-negative lesions. ...
Orenstein Jan Marc JM Department of Pathology, George Washington University , Washington, DC , - - 2014
Abstract The so-called "malignant fibrous histiocytoma (MFH)" has become progressively more enigmatic since entering the soft tissue tumor field, based on tissue culture studies performed almost 50 years ago. It inexplicably evolved from an exceedingly common soft tissue diagnosis into a problematic diagnosis. Because of the conundrum, clinicians require that ...
Lakshmanan Prakash Manikka PM Department of Radiology, Mahatma Gandhi Medical College & Research Institute, Pondicherry, - - 2014
Splenogonadal fusion is a rare congenital anomaly. We present the case of a 6-year-old boy who presented with a left inguinoscrotal swelling. With a clinical diagnosis of left congenital inguinal hernia the patient was taken up for explorative laparotomy where a transperitoneal band was noted adherent to the left testis. ...
Kocher Neil J - - 2013
A 35-year-old man presented with a painless left scrotal mass. Pathologic examination after orchiectomy revealed splenogonadal fusion. Splenogonadal fusion is an exceptionally rare, typically benign, congenital anomaly. Splenogonadal fusion should be included in the differential diagnosis of a left-sided testicular mass.
von Holstein Sarah Linéa SL Faculty of Health and Medical Sciences, University of Copenhagen, - - 2013
Tumours of the lacrimal gland are rare, but the prognosis may be grave. To date, no population-based incidence and distribution data on lacrimal gland tumours exist. In addition, almost nothing is known about the genetic profile of epithelial tumours of the lacrimal gland. We collected specimens and clinical files on ...
Hwang Michael J - - 2013
Mammary analogue secretory carcinoma (MASC) is a recently described malignancy of the salivary glands characterized by an ETV6-NTRK3 (EN) fusion gene. Morphologically, MASC is sometimes difficult to distinguish from acinic cell carcinoma. Consequently, identifying the chromosomal translocation is essential for diagnosis. We present a case of parotid gland MASC in ...
Massey Gene M - - 2013
Facet cysts are a relatively common source of neural compression in the lumbar spine. Open decompression and fusion are frequently used to treat the stenosis and instability associated with this pathology. Recently, anterior lumbar interbody fusion (ALIF) has increased in popularity for the treatment of lumbar degenerative conditions. ALIF may ...
Xu Chen - - 2013
The maxillofacial region develops during 3 to 8 weeks in an embryo. The process involves neural crest cell migration and proliferation as well as facial protrusion jointing and fusion. The maxillofacial region is one of the predilection sites of congenital malformations. We treated a 5-year-old Chinese boy with abnormal development ...
Oliveira André M - - 2013
USP6 (also known as TRE17) is a ubiquitin-specific protease that was identified as an oncogene in transfection experiments with Ewing sarcoma DNA 2 decades ago. Until recently, little was known about USP6 function and mechanisms of oncogenic activation. The identification of USP6 fusion genes in aneurysmal bone cyst (ABC) and, ...
Sheen Jae Jon JJ Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of - - 2013
Synovial cyst on prevertebral space of C1-2 joint is rare but may be associated hemorrhagic event. We describe a case of a 72-year-old woman who presented with sudden severe headache in her left occipital area with dyspnea. She had rheumatoid arthritis for 14-years. Large hemorrhagic cystic mass was seen around ...
Flucke Uta - - 2013
Chondroid lipomas are benign adipose tissue tumours. Their rarity and peculiar morphology can lead to misinterpretation, especially in small biopsies. Based on a recurrent translocation t(11;16)(q13;p13), the C11orf95-MKL2 fusion gene has been found in a few cases. Therefore, it seemed appropriate to look for this fusion gene in a larger ...
Grimm Nathan L NL Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT, - - 2013
Osteochondritis dissecans (OCD) has been defined as a localized process in which a focus of subchondral bone and adjacent articular cartilage separates from the surrounding bone. With the knee being the most common location for OCD development and the propensity for this lesion to be found in those who participate ...
Hiramoto Nobuhiro - - 2013
We report the case of a patient in whom the diagnosis of Ewing sarcoma arising from a soft tissue was made after successful treatment of diffuse large B-cell lymphoma. A 65-year-old woman presented with a rapidly growing mass in her left scapular region 8 years after successful chemotherapy with the ...
Zhang Yong - - 2013
Splenogonadal fusion is a rare congenital anomaly where the spleen is attached to either testicular or ovarian tissues. In present case, splenogonadal fusion presents as a large mass consciously connected to atrophic testis in left scrotum. The diagnosis of splenic gonadal fusion relies on radiologic and pathologic findings. Uniform density ...
Rudzinski Erin R - - 2013
The International Classification of Rhabdomyosarcoma (ICR) has provided diagnostic criteria for rhabdomyosarcoma (RMS) and formed the basis of histologic risk stratification since its publication in 1995. However, the recognition of new variants of embryonal rhabdomyosarcoma (ERMS), shifts in the diagnostic criteria of alveolar rhabdomyosarcoma (ARMS), the increasing use of myogenin ...
Mun Jong Hyeon - - 2012
The pathogenesis of juxtafacet cysts is closely related to degenerative instability of the lumbar spine and degenerative changes in the ligamentum flavum and the facet joint. A 56-year-old man presented with severe right thigh pain and numbness for 1 month after a laminar fracture of the L4 spine. Magnetic resonance ...
Groch Kátia R - - 2012
Skeletal tissues of 49 humpback whales Megaptera novaeangliae that stranded between 2002 and 2011 along the Abrolhos Bank seashore and its adjacent waters in Brazil were studied. Twelve (24.5%) animals presented pathological changes in one or more bones. Degenerative changes and developmental malformations were most frequent (10.2% each), followed by ...
Gurjar Hitesh Kumar - - 2012
Background:  Aneurysmal bone cysts are rare occurrences in the cervical spine. Surgical treatment in pediatric patients is a challenge. Complete tumor resection offers the best chance for cure. Description:  Diagnosis and surgical management of an expansile aneurysmal bone cyst of the cervical spine involving all three spinal columns in a ...
Taweevisit Mana - - 2012
Abstract Genitourinary tract malformations casusing hydrops fetalis are rare. The authors report a case of a female delivered at 32 weeks gestational age following a prenatal diagnosis of an abdominopelvic cystic mass with hydrops fetalis. The neonate was persistently hypoxic with unstable cardiovascular status and survived only 7 days. At ...
Tajiri Takuma - - 2012
To help pathologists avoid misdiagnosis of intraductal neoplasms arising from the pancreatobiliary system, we report two cases that illustrate diagnostic pitfalls. The first is of a 66-year-old man who complained of appetite loss. An early examination led to a diagnosis of intraductal papillary mucinous neoplasm. Macroscopically, a multilocular cyst without ...
Puffer Ross C - - 2012
OBJECTIVE: Previously we reported anterior decompression of C1-2 synovial cysts and subsequent posterior fusion in a large series. Although the surgical morbidity and mortality were acceptable, prior reports of stand alone C1-2 fusion with resolution of cyst compression presumptively by correction of joint instability were intriguing and obviated the need ...
Bydon Mohamad - - 2012
INTRODUCTION: Spinal synovial cysts are a known cause of back pain and radiculopathy. With the advent of highresolution imaging techniques, synovial cysts are increasingly diagnosed. There are a variety of treatment options for these lesions. This manuscript provides a detailed review of the differing treatment modalities for spinal synovial cysts. ...
Hannig M - - 2012
The purpose of this review is to highlight recent nanotechnological developments for remineralization of incipient caries lesions as well as biomimetic strategies for enamel synthesis based on the application of nanotechnology. Analysis of in vitro data indicates that apatite nanoparticles might be effective in reversing lesion progression in the outer ...
Farr Jack J Cartilage Restoration Center of Indiana, Indiana Orthopaedic Hospital, Greenwood, IN 46143, - - 2012
Patellofemoral (PF) dislocations are frequently associated with chondral injury. Chondral and osteochondral lesions are often associated with traumatic (high-energy) PF dislocations, whereas atraumatic (low-energy) PF dislocations in patients with significant PF risk factors have a much lower incidence of osteochondral damage. This article provides a historical overview and delineates the ...
Ellick Rachel M - - 2012
Mink (Mustela vison) exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-like chemicals have been reported to develop mandibular and maxillary squamous cell proliferation that results in the destruction of alveolar bone and eventual tooth loss. This jaw lesion has been reported in wild mink collected from areas contaminated with TCDD-like compounds and is a ...
Brea Beatriz - - 2012
INTRODUCTION AND OBJECTIVES: Benign lesions of the external auditory canal (EAC) are an infrequent cause of temporal bone CT scan requests. We are not usually well versed in the different pathologies located in the EAC, perhaps because it is "only" a conduit and the relevant anatomical structures are located in ...
- - 2012
Is there is a distinction between chronic periodontitis and aggressive periodontitis?
Yang Zhengming - - 2012
Bone epithelioid angiosarcoma is rare and generally shows positive immunostaining for epithelial markers. Multicentric bone epithelioid angiosarcoma is easily misdiagnosed as carcinoma, including metastatic carcinoma, multiple myeloma, and multiple lymphoma of bone.This article describes a case of multicentric bone epithelioid angiosarcoma. The patient was first misdiagnosed as having metastatic carcinoma. ...
Counihan K P - - 2012
Pre-eruptive intra-coronal radiolucency (PEIR) describes a radiolucent lesion located in the coronal den¬tine, just beneath the enamel-dentine junction of unerupted teeth. The prevalence of this lesion varies depending on the type and quality of radiographic exposure and age of patients used for assessment. The aetiology of pre-eruptive intra-coronal radiolucent lesions ...
Lambade Pravin N - - 2012
BACKGROUND: Neoplasms of peripheral nerve in the head and neck region are of common occurrence, but origin in the oral and para-oral tissues is uncommon and they rarely occur centrally within the jaws. Schwannoma is a benign neoplasm originating from the neural sheath of peripheral soft tissues, but its occurrence ...
Choudhry Osamah J - - 2012
Cystic epithelial lesions such as Rathke's cleft cysts (RCCs) and craniopharyngiomas may be difficult to distinguish on a clinical, radiographic, and sometimes histopathological basis. We describe a case of a giant 6.5 cm suprasellar cystic lesion that was presumed to be a craniopharyngioma based on the neuroimaging findings. The lesion ...
Revelles Juan M - - 2012
Benign lymphangioendothelioma is a rare locally infiltrative vascular neoplasm, presenting as a slow-growing, asymptomatic, reddish-violaceous plaque. Histopathologically, it is characterized by irregular and thin-walled vascular spaces, lined by a single and discontinuous layer of flat endothelial cells, dissecting dermal collagen bundles. We present the case of a 75-year-old man with ...
Dias João Madruga - - 2012
ABSTRACT: Pachydermodactyly is a superficial benign fibromatosis of unknown etiology; it is rare, more frequent in adolescent males, and characterized by painless swelling of the proximal interphalangeal joints (PIP) of the hands. Histologic examination of the skin shows epidermal hyperplasia and increased number of dermal fibroblasts and collagen fibers. We ...
Burdick Laura M - - 2012
Cutaneous collagenous vasculopathy is a rare microangiopathy of superficial dermal blood vessels. Patients present with telangiectatic macules, predominantly on the extremities. A skin biopsy specimen is necessary to distinguish cutaneous collagenous vasculopathy from generalized essential telangiectasia. Microscopically, cutaneous collagenous vasculopathy resembles the superficial telangiectasias of generalized essential telangiectasia but additionally ...
van Vliet Esther I - - 2012
We have noted that bone lesions on CT respond differently from soft-tissue lesions to treatment with [(177)Lu-DOTA(0),Tyr(3)]octreotate ((177)Lu-octreotate). We therefore compared the response of bone lesions with that of soft-tissue lesions to treatment with (177)Lu-octreotate in patients with gastroenteropancreatic and bronchial neuroendocrine tumors (NETs). METHODS: Forty-two patients with well-differentiated NETs ...
Kubota Yoshitaka - - 2012
BACKGROUND: Osteoblastomas and aneurysmal bone cysts each comprise 1% of primary bone tumours. As both osteoblastomas and aneurysmal bone cysts are not common, osteoblastomas with secondary aneurysmal bone cysts of calvaria are extremely rare. Only three cases describing a secondary aneurysmal bone cyst in the setting of a calvarial osteoblastoma ...
Gawande Pushkar Devidas - - 2012
ABSTRACT: Inflammatory pseudotumor (IP) is a nongranulomatous inflammatory process with no apparent local or systemic cause. The distinction between IP and malignant tumor is of great clinical importance. The incidence of IP in the head and neck region is very low. Inflammatory pseudotumor is a distinct pathological entity rarely found ...
Craig L E - - 2012
The goal of this study was to determine if cartilage lesions of the humeral head in adult dogs are the consequence of osteochondrosis dissecans or degenerative joint disease. A gross and histologic survey was performed of humeral head cartilage lesions of 155 dogs ranging in age from 1 week to ...
Kairy R R - - 2012
A case of an epiphyseal osteochondroma in the anteromedial aspact of left tibia in a 4 year old girl, who was presented with knocking between knees and limping. Surgical excision of this bony growth was curative and resolved the mechanical symptoms completely. Interesting clinical and imaging features are presented. The ...
Remotti Fabrizio - - 2012
Context.-The skeletal system may be affected by a variety of nonneoplastic lesions, which may potentially be confused with primary bone tumors on clinical, radiologic, and pathologic grounds. These conditions include fractures, infections, and reactive and degenerative processes, as well as an array of quasineoplastic entities, such as intramedullary cystic lesions ...
Spinner Robert J - - 2012
BACKGROUND: While extraneural ganglion cysts are common and well known, intraneural ganglia are rare and misunderstood. MATERIALS: We describe a patient with an intraneural ganglion in an unusual location, the deep branch of the ulnar nerve in the palm. We confirmed a connection to the triquetral-hamate joint on preoperative high-resolution ...
Douis H - - 2012
Benign cartilage tumours of bone are the most common benign primary bone tumours and include osteochondroma, (en)chondroma, periosteal chondroma, chondroblastoma and chondromyxoid fibroma. These neoplasms often demonstrate typical imaging features, which in conjunction with lesion location and clinical history, often allow an accurate diagnosis. The aim of this article is ...
Zhu Xiaoqin - - 2012
Papulonodular mucinosis (PM) is a cutaneous clue to the presence and activity of silent lupus erythematosus (LE), but the exact pathogenesis is still under secret. Moreover, the currently available treatments for PM are not satisfactory. To demonstrate the possibility of multiphoton microscopy (MPM) to trace the pathological state of PM ...
Burić Nikola - - 2012
Cartilaginous pathology of the jaws is relatively uncommon, owing the fact that the osteochondroma of the mandibular body are extremely rare. This paper elaborates on the rare case of endosteal (central) osteochondroma created 6 months after exodontia in the left body of the mandibula in tooth region #36. After obtaining ...
Naumova E A - - 2012
OBJECTIVES: The aim of this study was to investigate the effects of decreasing fluoride concentrations on repeated demineralizing challenges on human enamel MATERIALS AND METHODS: In 24 teeth, 3×3mm windows were prepared on the buccal and lingual sides and treated in a cycling demineralization-remineralization model. Remineralization was achieved with 100, ...
Thway Khin - - 2012
Chondroid lipoma is a rare, benign soft tissue tumor with features of both embryonal fat and embryonal cartilage that most often arises in the proximal limb and limb girdles of adult women. Histologically, it comprises nests and cords of rounded cells with granular eosinophilic or multivacuolated, lipid-containing cytoplasm within prominent ...
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