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Jeong Bo Young BY Department of Radiology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, - - 2014
Spontaneous bloody nipple discharge from a single duct is a significant clinical problem. When performing preoperative marking of the discharging duct, it is sometimes difficult to identify the duct owing to intermittent discharge. Precise preoperative marking of the discharging duct and intraductal lesions is very important to avoid unnecessary wide ...
Dawe Edward J C EJ Frimley Park Hospital, United Kingdom. Electronic address: - - 2014
We describe the endoscopic management of a large talar cyst using synthetic allograft gel. Three and a half years later the patient has returned to sport and repeat MRI demonstrates no further collapse of the cyst.
Minokadeh Ardalan - - 2014
A 92-year-old man presented for evaluation with a 1-month history of a rapidly growing asymptomatic pink nodule on his forearm. Biopsy results of the lesion demonstrated pathology consistent with Merkel cell carcinoma (MCC). Immunohistochemical studies displayed positive cytoplasmic staining for cytokeratin AE1/AE3, positive dot-like perinuclear staining for cytokeratin-20, diffuse cytoplasmic ...
Feng Guo-dong GD 1 Department of - - 2014
Early diagnosis and treatment of tuberculous meningitis saves lives, but current laboratory diagnostic tests lack sensitivity. We investigated whether the detection of intracellular bacteria by a modified Ziehl-Neelsen stain and early secretory antigen target (ESAT)-6 in cerebrospinal fluid leukocytes improves tuberculous meningitis diagnosis. Cerebrospinal fluid specimens from patients with suspected ...
Mallery Susan R SR College of Dentistry, The Ohio State - - 2014
Approximately 30% higher-grade premalignant oral intraepithelial neoplasia (OIN) lesions will progress to oral cancer. While surgery is the OIN treatment mainstay, many OIN lesions recur which is highly problematic for both surgeons and patients. This clinical trial assessed the chemopreventive efficacy of a natural-product based bioadhesive gel on OIN lesions. ...
Paris S S Department of Operative and Preventive Dentistry, Charité-Universitätsmedizin Berlin, Aßmannshauser Str. 4-6, 14197 Berlin, - - 2014
The aim of this in vitro study was to evaluate the penetration of an infiltrant and a sealant, when applied as recommended, into fissure caries lesions. The fissure systems of extracted human teeth were classified according to the International Caries Detection and Assessment System (ICDAS, codes: 0, 1, 2). Within ...
Schuetz Audrey N - - 2013
We report the finding of Iodamoeba butschlii amebic cysts on a liquid-based anal Pap smear from an HIV-positive male. Iodine staining of the smear confirmed the diagnosis. It is important to distinguish I. butschlii from pathogenic ameobae and other organisms seen on anal Pap smears. Diagn. Cytopathol 2013. © 2013 ...
Steffen Jonel - - 2013
To evaluate the diagnostic accuracy of methylene blue used as a non-invasive in vivo stain to detect ocular surface squamous neoplasia (OSSN). A test validation study was performed according to Standards for the reporting of diagnostic accuracy studies (STARD) guidelines on 75 consecutive patients who presented with ocular surface lesions ...
Jain Bhawna Bhutoria - - 2013
We report a 45-year-old male presenting with an intraoral mass originating from the right maxillary alveolar ridge. Radiologic investigations revealed osteolytic lesions in the right maxilla, skull, and lumbar vertebrae. This finding led to further investigations like electrophoresis of serum proteins for M band, quantitative estimation of immunoglobulins, urine electrophoresis ...
Berson Diane - - 2013
Setting: Acne vulgaris is characterized by comedones, papules, pustules, and secondary lesions. Historically, it has been considered a disease primarily affecting adolescents, but recent reports over the past three decades suggest an increasing prevalence in adults, particularly women. Adapalene was developed for the topical treatment of acne. Adapalene (6-[3-(l-adamantyl)-4-methoxyphenyl]-2-naphthoic acid) ...
Pallagatti Shambulingappa S M.D.S., Professor, Department of oral medicine and radiology, M.M. College of Dental Sciences and Research, Mullana, Ambala, Haryana, - - 2013
Prognosis of oropharyngeal squamous cell carcinoma depends on early diagnosis, despite advanced surgical techniques, the 5-year survival rate remains ~40-50%. Unfortunately, it is usually detected when it becomes symptomatic. This requires treatment which gives rise to a high rate of morbidity and mortality and, furthermore, early detection of oro-pharyngeal pre-malignant ...
Reja Abu Hena Hasanoor - - 2013
Background: Leprosy is not always an easy disease to diagnose, and patients can remain undiagnosed for longtime, not only at the peripheral clinics but also even at places with higher medical facilities, so, there is an urgent need for rapid and definitive modalities for leprosy diagnosis. This prospective study evaluates ...
Pandya Himani B - - 2013
To evaluate Helicobacter pylori (H. pylori) detection by histological staining methods, and to compare with those of Gram staining and polymerase chain reaction (PCR). This is a cross-sectional study conducted at the Department of Microbiology, Shree P. M. Patel Paramedical College, Anand, Gujarat, India on 436 patients attending the Deep ...
Feng Xin-Zhi - - 2013
Iodine staining during endoscopy has been successfully used to detect early carcinomatous and precancerous lesions in the esophagus, cervix, and oral cavity. The objective of this study was to determine the diagnostic accuracy of fiberoptic ductoscopy (FDS) plus in vivo iodine staining for intraductal proliferative lesions of the breast. We ...
Mewes Philip W - - 2013
BACKGROUND: Diagnosis of intestinal metaplasia and dysplasia via conventional endoscopy is characterized by low interobserver agreement and poor correlation with histopathologic findings. Chromoendoscopy significantly enhances the visibility of mucosa irregularities, like metaplasia and dysplasia mucosa. Magnetically guided capsule endoscopy (MGCE) offers an alternative technology for upper GI examination. We expect ...
Frieling Gretchen W - - 2013
We present a case of an otherwise healthy 81-year-old gentleman with multiple asymptomatic, erythematous, indurated papules and plaques, ranging in size from 0.5 to 1.5 cm, involving the dorsal, lateral, and palmar surfaces of the fingers bilaterally. A clinical suspicion of erythema elevatum diutinum (EED) led to initial treatment with ...
Singh Chanchal - - 2013
A 27-year-old G3P1 presented to the gynaecology emergency department with heavy vaginal bleeding for 16 days. Transvaginal ultrasound showed vascular cystic spaces in the myometrium raising a suspicion of choriocarcinoma. However, β-human chorionic gonadotrophin (β-hCG) was negative in both the urine and serum. Angiography confirmed the rarer diagnosis of uterine ...
Belgaumi Ui - - 2013
Papanicolaou staining is commonly used for staining exfoliative cytology smears with Romanowsky stains being used sparingly. Leishman Giemsa (LG) cocktail, being a relatively new staining technique, has not been used in exfoliative cytology. This easy, cost-effective and one-step technique warrants further study because of its potential application in screening of ...
Baig Muhammad Kashif - - 2012
Objective: To observe the role of p63 staining in evaluation of morphologically ambiguous lesions of prostate. Study Design: Descriptive (case series) study. Place and Duration of Study: Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, from March to September 2010. Methodology: p63 immunohistochemistry staining was performed on 30 cases ...
Ravarino Alberto - - 2012
Cytologic findings of glandular lesions of the cervix uteri are often difficult to evaluate. We studied the usefulness of CINtec PLUS p16/Ki-67 double stain (mtm laboratories, Heidelberg, Germany) for the diagnosis of glandular lesions. The study included 47 abnormal results on liquid-based cytologic tests with a subsequent histologic diagnosis of ...
Tada Takeshi - - 2012
BACKGROUND: WE HAVE SOMETIMES NOTED ABNORMAL ANGIOGRAPHIC CORONARY DILATATION, 50% OF THE REFERENCE VESSEL, AT THE SITE OF SIROLIMUS-ELUTING STENT IMPLANTATION, SUGGESTING CONTRAST STAINING OUTSIDE THE STENT STRUTS AND NAMED THIS FINDING PERI-STENT CONTRAST STAINING (PSS). LITTLE WAS KNOWN ABOUT OPTICAL COHERENCE TOMOGRAPHY FINDINGS OF LESIONS WITH PSS.METHODS AND RESULTS: ...
Pang Dachling - - 2012
The structural complexity of terminal myelocystocele (TMC) precludes a recognizable link to spinal cord development and therefore a plausible embryogenetic theory. To demystify TMC using clinical, imaging, surgical, electrophysiological, and histopathological data and to propose a theory of embryogenesis. Our series consisted of 4 newborns and 6 older children. All ...
Raabe Anna - - 2012
Intracerebral vascular malformations including cavernous angiomas (CAs) and arteriovenous malformations (AVMs) are an important cause of chronic pharmacoresistant epilepsies. Little is known about the pathogenetic basis of epilepsy in patients with vascular malformations. Intracerebral deposits of iron-containing blood products have been generally regarded as responsible for the strong epileptogenic potential ...
Lehman Thomas J A - - 2011
The mucopolysaccharidoses (MPSs) often present a diagnostic challenge, particularly for patients who have more slowly progressive disease phenotypes, as early disease manifestations can be subtle or non-specific. However, certain types of bone and joint involvement should always prompt consideration of an MPS diagnosis, such as early joint involvement without classic ...
Corcos Olivier - - 2011
OBJECTIVES: Intraductal papillary mucinous neoplasms (IPMN) of the pancreas evolve from dysplasia to invasive adenocarcinoma. The aims of this study were to look for candidate protein profiles in IPMN mucus according to histological grade, using a differential proteomic technique, and to highlight protein peaks associated with malignant transformation. METHODS: Forty-three ...
Glastonbury Christine M - - 2011
The third ventricle lies in the center of the brain. It is surrounded by critical nuclear structures (the hypothalamus and thalami) and important glandular structures (the pituitary and pineal glands). Although a wide array of pathologic processes may involve the third ventricle, most are extrinsic masses. By understanding the anatomic ...
Guitera Pascale - - 2011
In the past few decades, rapid improvements in noninvasive optical technologies have revolutionized the diagnosis of early-stage melanoma. Current knowledge and limitations of these tools will be reviewed in this article. Dermoscopy has been recognized as the 'gold standard' in the screening phase. Digital dermoscopy monitoring and total-body photography are ...
Ahmad Fiaz - - 2011
Helicobacter pylori is an important cause of chronic gastritis, gastric ulceration and gastric malignancies as gastric carcinoma and MALT lymphoma. Its definitive diagnosis is based on histopathology. Routine H & E stain is not very effective in its detection, immune-stains and fluorescent stains are costly. Need for simple cheap and ...
O'Brien M F - - 2011
Clinical disease and mortalities due to disseminated visceral coccidiosis were identified for the first time in a group of captive juvenile Eurasian cranes (Grus grus) in the UK during 2008. Presumptive diagnosis was made from the finding of granulomatous nodules in the liver, spleen and other organs at gross postmortem ...
Bell G W - - 2011
The maxillary sinus is the paranasal sinus that impacts most on the work of the dentist as they will often be required to make a diagnosis in relation to orofacial pain that may be sinogenic in origin. Maxillary sinus disease is often coincidentally observed on radiographs, and dentists often have ...
Shannon Kathleen M - - 2011
HD is a complex illness, with a broad clinical picture that begins years before clear motor onset and evolves over decades to a terminal state of extreme disability. It challenges the resources of families and communities and the skills of medical and ancillary health care providers. A broader understanding of ...
Dahodwala Nabila - - 2011
Racial differences in the observed prevalence of Parkinson's disease (PD) may be due to delayed diagnosis among African-Americans. We sought to compare the stage at which African-American and white PD patients present for healthcare, and determine whether perception of disability accounts for racial differences. Using records of veterans with newly ...
Heath C A - - 2010
Introduction Establishing an early clinical diagnosis in variant Creutzfeldt-Jakob disease (vCJD) can be difficult, resulting in extended periods of uncertainty for many families and sometimes a view that patients have been subjected to unnecessary investigations. This issue is accentuated by the progressive nature of vCJD and by the difficulty in ...
Zhang Yi Wei - - 2010
The tissue cyst wall of Toxoplasma gondii is a stage-specific structure that is produced by modification of the bradyzoite-containing parasitophorous vacuole. It is a limiting membrane structure and is critically important for cyst survival and transmission of infection. Studies on the structure and function of the cyst wall should provide ...
Bujons Anna - - 2011
Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Testicular tumours in childhood are very rare. Historically, most of these tumours have been considered malignant, but more recent studies indicate that benign lesions, particularly teratoma, are much more frequent ...
Powis Mark - - 2010
Neonatal renal tumours are rare, with only 7% of all neonatal tumours arising from the kidney. Presentation is usually as a flank mass or as a coincidental finding on either antenatal or postnatal ultrasound. Mesoblastic nephroma is the most common tumour to be found at this age, but Wilms' tumour ...
Miranda Mario Fernando Ribeiro de - - 2010
Biopsies are occasionally necessary to confirm the diagnosis of secondary-stage syphilis, currently achieved by clinico-serological correlation. However, histopathologic examination may offer clues that can lead to the diagnosis of the disease in previously unsuspected or unusual cases. We report the case of a 35-year-old male patient with vitiligo-like lesions for ...
Xu X D - - 2010
Gastric glomus tumours are rare and clinically recognized as benign. Nevertheless, some show biological behaviour similar to that of malignant lesions. During the last 40 years, we have encountered only one gastric glomus tumour. Analysis of frozen sections of this tumour suggested a mesenchymal tumour with malignant potential. Three mitoses ...
Stewart Douglas R - - 2010
Glomus tumours are benign painful tumours of the glomus body, a thermoregulatory shunt in the digits. Glomus tumours of the fingers and toes are associated with the monogenic disorder neurofibromatosis type 1 (NF1) and are recently recognised as part of the NF1 phenotype. A multi-institutional experience with 15 individuals with ...
Vandenberghe Lore - - 2010
Plain radiography can help in confirming the clinical diagnosis of a subungual glomus tumour, as erosive changes in the distal phalanx are present in 22% of cases. Such changes will be more easily identified on a lateral radiograph with the painful finger and its contralateral counterpart pointing toward each other: ...
Ahmed Hashim U HU Division of Surgery and Interventional Sciences, University College London and UCH/UCL Comprehensive Biomedical Research Centre, London, UK. - - 2010
Prepubertal testicular and paratesticular tumours are a rare group of tumours, distinct from postpubertal paediatric and adult tumours of this region. Tumours within this group are testicular germ-cell tumours (such as benign teratoma, epidermoid cyst and malignant yolk-sac tumours) and stromal tumours (such as juvenile granulosa-cell, Leydig-cell, and Sertoli-cell tumours). ...
Hardcastle M R - - 2010
Tumour-induced osteomalacia of humans is a renal phosphate-wasting syndrome associated with slow-growing mesenchymal tumours. Seventy to eighty percent of these tumours are classified as phosphaturic mesenchymal tumours of mixed connective tissue, that strongly resemble haemangiopericytomas. Affected individuals develop osteomalacia, with bone and muscle pain, hypophosphataemia, and inappropriately low concentrations of ...
De Silva Naomi - - 2010
Oncolytic viruses (OVs) are selected based on their ability to eliminate malignancies by direct infection and lysis of cancer cells. Originally, OVs were designed to target malignancies by taking advantage of the defects of cancer cells observed in vitro. Subsequent analysis of virus delivery and spread in vivo has demonstrated ...
Smakal O - - 2010
The authors present a case of testicular appendix torsion that mimicked a tumour of the paratesticular tissues due its calm clinical course, objective palpation and ultrasound finding. The torsion of the big testicular appendix was found during surgery from an inguinal approach. The histological examination confirmed only minimal inflammation changes ...
Rennie I G - - 2010
Vasoproliferative tumours are uncommon retinal lesions that may occur in isolation (primary) or in association with another ocular condition (secondary). They may be unilateral or bilateral and have a predilection for the peripheral inferior temporal quadrant of the retina. Vasoproliferative tumours can be associated with abnormalities of the macular, including ...
Hogan William R - - 2010
Coding categories of diseases, injuries, symptoms, findings, etc. with ICD-9-CM necessarily imparts a loss of information vs. coding such entities with a terminology or ontology-a consequence of the nature of classifications. However, to our knowledge, no one has attempted to quantify this information loss or conversely, the information to be ...
Portas T J - - 2010
A testicular mass was identified by ultrasonography performed during a routine reproductive evaluation of an adult male southern black rhinoceros (Diceros bicornis minor). Histological examination of a testicular biopsy supported a presumptive diagnosis of testicular neoplasia. Hemi-castration was performed to excise the affected testis and a pathological diagnosis of a ...
Collado Manuel - - 2010
The importance of cellular senescence, which is a stress response that stably blocks proliferation, is increasingly being recognized. Senescence is prevalent in pre-malignant tumours, and progression to malignancy requires evading senescence. Malignant tumours, however, may still undergo senescence owing to interventions that restore tumour suppressor function or inactivate oncogenes. Senescent ...
Lamouille Samy - - 2009
SnoN was first identified based on its homology with the proto-oncogene c-Ski, and has since been implicated as a promoter of oncogenic transformation and cancer progression. Consistent with a role as proto-oncogene, SnoN negatively regulates TGF-beta signalling, through its interactions with Smad complexes. Thus, SnoN inhibits the growth inhibitory effect ...
Roperto S - - 2010
Four hundred bovine urothelial tumours and tumour-like lesions were classified in accordance with the 2004 World Health Organization (WHO) morphological classification for human urothelial tumours. The spectrum of neoplastic lesions of the urinary bladder of cattle is becoming wider and bovine urothelial tumours share striking morphological features with their human ...
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