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Okamura Takuma T 1Department of Molecular Pathology, Shinshu University Graduate School of Medicine 2Division of Gastroenterology, Department of Medicine, Shinshu University School of Medicine, Matsumoto 3Division of Tumor Pathology, Department of Pathological Sciences, Faculty of Medical Sciences, University of Fukui, Eiheiji, - - 2014
Nodular gastritis is a form of chronic Helicobacter pylori gastritis affecting the gastric antrum and characterised endoscopically by the presence of small nodular lesions resembling gooseflesh. It is generally accepted that hyperplasia of lymphoid follicles histologically characterises nodular gastritis; however, quantitative analysis in support of this hypothesis has not been ...
Berney Dan M DM Queen Mary University of London, - - 2014
Classical seminoma is the most commonly encountered testicular neoplasm. Most clinically localised seminomas are now managed by surveillance, though adjuvant chemo or radiotherapy can be given. The diagnosis of seminoma can be relatively straightforward, but may present unforseen challenges leading to inappropriate treatment or serious misdiagnosis in a number of ...
Jones Claire Ann CA Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto - - 2014
Abstract Intrachromosomal insertions are rare and difficult to diagnose. However, making the correct diagnosis is critical for genetic risk assessment, and prenatal and preimplantation genetic diagnosis outcomes. We present a case of preimplantation genetic diagnosis (PGD) using array comparative genomic hybridization (aCGH) following trophectoderm biopsy of embryos created after in ...
Wightman Paul P Veterinary Teaching Hospital, Radiology, Massey University, Palmerston North, 4442, New - - 2014
A 12-day-old Brown Kiwi (Apteryx mantelli) was presented with anorexia, torticollis, head-tilt, and coelomic distension. Radiographs showed an ill-defined, fat-opaque, coelomic mass displacing viscera craniodorsally. Curvilinear mineral opacities were superimposed over the ventral aspect of the mass. Computed tomography demonstrated the presence of mineral within the periphery of a fat ...
Zreik Riyam R Department of Pathology, Baylor Scott & White and Texas A&M, Temple, - - 2014
Head and neck liposarcomas, while rare, tend to be subcutaneous and well-differentiated. Dedifferentiated liposarcomas of the head and neck are exceedingly rare in the literature. We present a case of a dedifferentiated liposarcoma arising in the soft tissue of the posterior neck of an 86-year-old man and diagnosed by fine-needle ...
Vedantam Aditya A Departments of Neurosurgery (AV, DY) and Ophthalmology (RF), Baylor College of Medicine, Houston, - - 2014
: A 62-year-old woman presented with a chronic left homonymous visual field defect because of a right occipital cyst. Serial visual field examination documented stable visual fields for 12 months, after which there was worsening of visual fields associated with enlargement of the cyst. Surgical decompression of the occipital cyst ...
Chung Tae-Ho - - 2014
Multiple organ invasion by keratinophilic fungi in the green iguana (Iguana iguana) has not been previously reported. In this case, a 1-yr-old female green iguana presented with a nodular, darkly discolored skin lesion surrounded by necrosis in the right ventral abdominal region. A cytologic examination of the fine needle aspiration ...
Andrade C T CT Physics Institute of Sao Carlos, University of Sao Paulo. Electronic address: - - 2014
Non melanoma skin cancer is the most common cancer lesion worldwide. In Brazil, it represents 95% of all skin cancer lesions, and 25% of all tumor types. Early diagnosis allows treatment at initial stages of the disease, improving patient's prognosis. Thus, it is of great importance the development of techniques ...
Zhang Chao C Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke (C.Z., A.I.I.Y., C.Y., C.S., P.C., J.D.H., Z.Z., K.A.Z.), and Laboratory of Pathology, National Cancer Institute (L.V., S.I.M., L.S., Z.A., S.D.P., A.G., M.M.Q.), National Institutes of Health, Bethesda, Maryland 20892; and Department of Orthopedics (C.Z.), Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, - - 2014
Context: Carcinoids have rarely been described in von Hippel-Lindau (VHL) disease. Objective: We describe the first reported case of a patient with VHL who developed a pulmonary carcinoid that subsequently metastasized to a pre-existent cranial hemangioblastoma. Results: Histological and immunohistochemical features of the metastatic lesion were similar to the primary ...
Janssen Julius J Department of Pulmonary Diseases A75, Canisius Wilhelmina Hospital, Post box 9015, 6500 GS Nijmegen, - - 2014
Thoracoscopy has proved to be a reliable tool to demonstrate or exclude pleural malignancy, with a diagnostic yield of at least 90%. (Auto)fluorescence thoracoscopy is a technique used in clinical practice for the early detection of malignant changes in the pleura in order to increase the detection rate of early ...
Turner Gregory G GG 1  Pennsylvania Game Commission, 2001 Elmerton Avenue, Harrisburg, Pennsylvania 17710, - - 2014
Abstract Definitive diagnosis of the bat disease white-nose syndrome (WNS) requires histologic analysis to identify the cutaneous erosions caused by the fungal pathogen Pseudogymnoascus [formerly Geomyces] destructans (Pd). Gross visual inspection does not distinguish bats with or without WNS, and no nonlethal, on-site, preliminary screening methods are available for WNS ...
Schwendicke F F Department of Operative and Preventive Dentistry, Charité- Universitätsmedizin, Berlin, - - 2014
One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decreases the acceptance of minimally invasive excavation and might lead ...
Garza-Ramos Rafael De la - - 2014
Objectives: The use of fluorescent compounds and techniques in neurosurgery has aided in delimitating tumor margins and visualizing blood dynamics in vascular malformations. However, the use of these techniques for the treatment of spinal lesions has not been well established. Methods: In this manuscript, we conduct a literature review to ...
Stewart Colin Jr CJ Department of Histopathology, King Edward Memorial Hospital, Perth; School of Womens' and Infant's Health, University of Western - - 2014
To perform a population-based review of monomorphic endometrial stromal tumours and their histological mimics presenting over a 20-year period including an evaluation of fluorescence in situ hybridization (FISH) for the JAZF1 and YWHAE breakaparts. Forty-nine tumours were examined comprising 13 histological mimics and 36 endometrial stromal tumours (6 stromal nodules ...
Drakaki Eleni E University of Athens, Andreas Syggros Hospital, Department of Dermatology, Photobiology Unit, 5 Dragoumi Street, 16121 Athens, - - 2014
ABSTRACT. Noninvasive treatments are increasingly being used for the management of basal cell carcinoma (BCC), the predominant type of nonmelanoma skin cancer, making the development of noninvasive diagnostic technologies highly relevant for clinical practice. Laser-induced fluorescence (LIF) spectroscopy emerges as an attractive diagnostic technique for the diagnosis and demarcation of ...
Matsukuma Y Y Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
Polyomavirus BK nephropathy (BKVN) is an important infectious complication in kidney transplant patients. Regular screening using polymerase chain reaction for BK virus DNA in plasma and urinary cytology is effective for early diagnosis of BKVN. However, methods of follow-up and therapeutic targets are not well described. Ten patients with BKVN ...
Machado Daniel Escorsim DE Health and Biological Sciences Center, Pharmacy College, State University of East Zone, and Development and Cell Biology Research Program, Biomedical Sciences Institute, Federal University of Rio de Janeiro, Rio de Janeiro, - - 2014
Endometriosis involves the growth of endometriotic tissue outside the uterine cavity, and is frequently associated with different malignancies. A well-reported alteration in the disease microenvironment is the proliferation of new blood vessels around the lesions, as part of a necessary repertory to contribute to the invasiveness and development of infiltrating ...
Garcia-Allende P Beatriz PB Chair for Biological Imaging & Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Trogerstr. 9 D-81675, München, - - 2013
White-light surveillance colonoscopy is the standard of care for the detection and removal of premalignant lesions to prevent colorectal cancer, and the main screening recommendation following treatment for recurrence detection. However, it lacks sufficient diagnostic yield, exhibits unacceptable adenoma miss-rates and is not capable of revealing functional and morphological information ...
Feng Dilu - - 2013
In endometriosis research, endometriosis-like lesions are usually induced in rodents by transplantation of isolated endometrial tissue fragments to ectopic sites. In the present study, we investigated whether this approach is affected by the cellular composition of the grafts. For this purpose, endometrial tissue fragments covered with luminal epithelium (LE(+)) and ...
Ponti Giovanni - - 2013
Although the 'gold standard' for melanoma diagnosis remains histopathological analysis, presently dermoscopists play a significant role in the diagnostic process. However, even a combined approach may not allow a clear-cut judgment on equivocal melanocytic lesions. Fluorescence in-situ hybridization (FISH) can offer assistance in the evaluation of chromosome abnormalities associated with ...
Templeton Adam A Division of Gastroenterology, Department of Medicine, University of Washington, School of Medicine, Seattle, WA, - - 2013
Probe-based confocal microscopy (pCLE) is actively being investigated for applications in the esophagus and stomach. The use of pCLE allows real-time in vivo microscopy to evaluate the microarchitecture of the mucosal epithelium. pCLE appears to be particularly useful in identifying mucosal dysplasia and early malignancies that cannot be clearly distinguished ...
Bahrololoomi Zahra - - 2013
Early detection of smooth surface lesions is important for appropriate management and monitoring of dental caries. The purpose of this in vitro study was to evaluate the efficacy of laser fluorescence to detect demineralization and remineralization of smooth enamel surfaces. In this in vitro study, 132 enamel blocks of semi-impacted ...
Manny Ted B TB Department of Urology, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina 27103, - - 2013
Indocyanine green (ICG) is emerging as a potential adjunct to robot-assisted partial nephrectomy by its ability to aid in the real-time identification of renal vasculature, renal masses, and the renal mass-parenchymal margin. The fluorescence patterns of renal masses have not been adequately described according to histology, and it remains unknown ...
Matsumoto Keitaro - - 2013
Localized emphysema is difficult to detect on normal thoracoscopy. Indocyanine green (ICG) was used to precisely delineate an emphysematous lesion using an infrared camera system in a 75-year-old woman with a large emphysematous lesion in the right lower lobe. Due to repeated infections of the emphysematous lesion, right basal segmentectomy ...
Reddy Shyam Prasad SP Department of Oral Pathology, Staff Quarters, Sarda Estate, Aditya Dental College and Hospital, Beed, Maharashtra, - - 2013
Early detection of potentially malignant lesions and invasive squamous-cell carcinoma in the oral cavity could be greatly improved through techniques that permit visualization of subtle cellular changes indicative of the neoplastic transformation process. One such technique is confocal microscopy. Combining rapidity with reliability, an innovative idea has been put forward ...
Rosolen Débora C B - - 2013
It is difficult to differentiate tumor cells in pleural fluid from reactive benign mesothelium. Fluorescence in situ hybridization (FISH) can increase diagnostic accuracy. Two hundred pleural fluid samples were analyzed by using FISH probes for chromosomes 11 and 17. Histological analysis was used to diagnose cancer. Clinical, radiological, and histological ...
Cicchi Riccardo - - 2013
Two optical fibre-based probes for spectroscopic measurements on human tissues were designed and developed. The two probes combine fluorescence and Raman spectroscopy in a multimodal approach. The fluorescence excitation was provided by two laser diodes emitting in the UV (378 nm) and in the visible (445 nm) range, while a ...
Truchuelo M T - - 2013
Introduction  It has already been demonstrated the high efficacy of photodynamic therapy (PDT) for Bowen's disease (BD) treatment. Fluorescence diagnosis consists on registration of the fluorescence emitted by tissue after application of a photosensitizer, indicating presence of tumoral cells. It has been described as a useful tool for actinic keratosis. ...
Chávez-Munguía Bibiana - - 2013
During Acanthamoeba castellanii trophozoite-cysts differentiation, four morphological stages were identified by scanning electron microscopy: trophozoite, precyst, immature cysts, and mature cysts. Fluorescence microscopy reveals the presence of small cumulus of actin in the cytoplasm of precysts after treatment with rhodamine phalloidin. By the contrary, in mature cysts, fluorescence was not ...
Yoon Won Jae - - 2013
Differentiating between malignant and benign bile duct strictures is often challenging. Endoscopic retrograde cholangiopancreatography with brush cytology and/or endobiliary forceps biopsy is routinely performed. Advanced cytologic methods such as fluorescence in situ hybridization or digital image analysis increases the sensitivity of cytology. Endoscopic ultrasonography enables detailed examination of tissues surrounding ...
Takayama Kei - - 2013
Sebaceous adenomas are found mainly in elderly individuals and are usually tan, pink, or yellow nodules or papules, usually approximately 5 mm in the largest size. A 65-year-old man presented with a progressively enlarging exophytic lesion in the right eyelid for 3 months. External examination revealed a yellowish-pink growth measuring ...
Seidenari Stefania - - 2013
Multiphoton laser tomography (MPT) combined with fluorescence lifetime imaging (FLIM) is a non-invasive imaging technique, based on the study of fluorescence decay times of naturally occurring fluorescent molecules, enabling a non-invasive investigation of the skin with subcellular resolution. The aim of this retrospective observational ex vivo study, was to characterize ...
Sieroń Aleksander - - 2013
Fluorescence diagnosis is a fast, easy, noninvasive, selective, and sensitive diagnostic tool for estimation of treatment results in oncology. In clinical practice the use of photodynamic diagnosis is focused on five targets: detection for prevention of malignant transformation precancerous changes, detection of neoplasmatic tissue in the early stages for fast ...
Deonizio Janyana M D - - 2012
The purpose of this review is to summarize the most important molecular techniques for the diagnosis of cutaneous lymphomas. When making a diagnosis, we are looking for the solid clinicopathological correlation. Molecular analysis includes immunophenotyping and clonality analysis, and is important for 2 principal reasons: (1) to confirm the diagnosis ...
Honda T - - 2012
AIM: To analyse the correlation between computed tomography (CT) findings of small lung adenocarcinomas and the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification of Lung Adenocarcinoma. MATERIALS AND METHODS: A retrospective review of 300 lung adenocarcinoma lesions (size ≤20 mm) after surgical resection in 295 ...
McNamara Kristin K - - 2012
Direct visual fluorescent examination (DVFE) is a proposed adjunct to conventional oral examination (COE). We evaluate the benefit of DVFE in screening for potentially malignant mucosal lesions in a general population of patients presenting for dental care. A total of 130 patients were evaluated by COE followed by DVFE. Areas ...
Nijhawan Rajiv I - - 2012
Histopathologic examination is the gold standard for the diagnosis of melanocytic lesions, including melanoma, and guides management options and disease prognosis based on the depth of invasion. Although most melanomas can be readily distinguished from benign nevi, some pigmented lesions are more ambiguous and can be challenging to interpret as ...
Shukla Deepika - - 2012
PURPOSE: Previous studies have reported significantly higher concentrations of serum DNA in various types of cancers. Thus the study aims to determine whether circulating free DNA (CFDNA) can aid in the diagnosis and prognosis of oral epithelial dysplasia and oral squamous cell carcinoma (OSCC). MATERIALS AND METHODS: A nonrandomized case-control ...
Wilson Thomas C - - 2012
ABSTRACT:: Early cutaneous Lyme disease, erythema migrans, manifests as a gyrate erythema at the site of a tick bite. The standard histopathologic description is that of a superficial and deep perivascular lymphocytic infiltrate in which plasma cells are identified at the periphery of the lesion and eosinophils in the center. ...
Mir F - - 2012
A stud dog was presented for acquired infertility. Haematospermia and teratozoospermia were found on two ejaculates 2 weeks apart. A presumptive diagnosis of prostatitis was made follo-wing -ultrasound examination. An ultrasound-guided needle core biopsy was performed under general anaesthesia, revealing a mild chronic macrophagic and plasma cell prostatitis with intracytoplasmic ...
Culver Emma L - - 2012
IgG4-related disease (IgG4-RD) is an increasingly recognised inflammatory and fibrosing condition that commonly shows multisystem involvement. The disease may mimic malignancy and other inflammatory or immune-mediated disorders, but usually has a good response to corticosteroid therapy, underlining the requirement for recognition of the condition. Accurate diagnosis requires careful interpretation of ...
Kakati Bobby R - - 2012
The gastrointestinal (GI) tract is the predominant site for primary extranodal non-Hodgkin lymphomas (NHL), accounting for 5-10% of all extranodal disease. A 74-year-old man underwent colonoscopy for a positive fecal occult blood test. Colonoscopy revealed a 3.5-cm polyp in the descending colon and was removed by snare cautery polypectomy. Post-polypectomy ...
Eryılmaz Ozlem Gün OG IVF Unit, Zekai Tahir Burak Women Hospital, Ankara, - - 2012
The gonadotropin-releasing hormone-agonist (GnRH-a) treatment during in vitro fertilization (IVF) sometimes causes a functional ovarian cyst during the administration period before gonadotropin stimulation, as an undesired event. The aim of this study was to analyze the effect of these cysts on the IVF outcomes. Out of 981 IVF cycles, 78 ...
Chourmouzi Danai D Danai Chourmouzi, Stamatia Potsi, Anestis Moumtzouoglou, Elisavet Papadopoulou, Kostas Drevelegas, Department of Radiology, Interbalkan Medical Center, GR 57001 Thessaloniki, - - 2012
The purpose of this essay was to illustrate the radiological and pathological findings in a wide spectrum of dural lesions mimicking meningiomas. Familiarity with and knowledge of these findings will narrow the differential diagnosis and provide guidance for patient management. In this pictorial review, we describe the following entities: Solitary ...
Koletsa Triantafyllia - - 2012
ABSTRACT: Primary cutaneous plasmacytoma is defined as monoclonal proliferation of plasma cells that arises primarily in the skin without evidence of systemic disease. We present an extremely rare case of a young adult diagnosed with solitary plasmacytoma. A 20-year-old woman presented with a pruritic erythematosquamous indurated plaque on the inner ...
Ciccarelli Olga - - 2012
Double inversion recovery (DIR) MRI is a relatively novel imaging technique in which both white matter (WM) and CSF signals are suppressed; cortical lesions are thereby identified as focal areas of hyperintensity relative to surrounding gray matter (GM).(1) Three dimensional DIR increases intracortical lesion detection by 500% compared to lesion ...
Inose Yuri - - 2012
Adenoid cystic carcinoma (ACC) is a malignant neoplasm that commonly arises in the major or minor salivary gland and usually forms mass lesions. Here, we report a case of ACC involving a 56-year-old man, who displayed right multiple cranial nerve palsies with ipsilateral severe facial pain but not any mass ...
Oshima Yasuko - - 2012
We report a middle-aged Japanese man who had a past history of malignant lymphoma with tubulointerstitial nephritis (TIN) presenting a high serum immunoglobulin G4 (IgG4) concentration and bilateral kidney enlargement and swelling of many lymph nodes. Although lymph node biopsy was not evident of a recurrence of lymphoma, kidney biopsy ...
Beeksma F A - - 2012
: Following intrauterine fetal death (IUFD), the placental fetal vessels undergo regressive changes. These changes are virtually indistinguishable from lesions that are the result of fetal vascular thrombosis (FVT). This study investigated the relation between these lesions and maternal thrombophilia. : Placenta slides of 65 IUFDs with known maternal thrombophilia ...
Caramanos Zografos - - 2012
To better characterize the relationship between cerebral white matter lesion load (CWM-LL) and clinical disability by (1) covering the entire range of the Kurtzke Expanded Disability Status Scale (EDSS), (2) minimizing nonbiological sources of variability, and (3) increasing pathologic specificity by studying CWM lesions that are hypointense on T1-weighted magnetic ...
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