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Pawoo Nogba N From the Department of Pathology & Laboratory Medicine, Rutgers-New Jersey Medical School, Newark, New - - 2014
Placental mesenchymal dysplasia is a rare placental lesion characterized by stem villous cystic dilation and vesicle formation, placentomegaly, and vascular abnormalities. It can be associated with growth restriction, stillbirth, Beckwith-Wiedemann syndrome, and some chromosomal abnormalities, and needs to be distinguished from its main differential diagnosis, hydatidiform mole.
Narula Vineet V Department of ENT, BL Taneja block, Maulana Azad Medical College and Associated Lok Nayak, G.B. Pant and G.N.E.C. Hospitals, New Delhi 110002, India. Electronic address: - - 2014
Yolk sac tumour, also known as endodermal sinus tumour (EST) is malignant germ cell tumours usually seen in children less than 3 years of age, involving the testis. We describe a rare case of extragonadal primary yolk sac tumour of the temporal bone in a 2.5 years old child presenting ...
Jeon Eun Kyoung EK Division of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, - - 2014
Anticancer agents can induce sarcoidosis. Interferon-alpha, which is used for the treatment of malignant melanoma and renal cell cancer, is one causative agent of sarcoidosis. However, there are few reports of interferon-alpha-induced sarcoidosis in patients with malignant melanoma. Clinically, it is important to consider the possibility of sarcoidosis in such ...
Alerić Ivan - - 2014
Pulmonary tumorlets are small, often multiple nodular proliferations of pulmonary neuroendocrine cells. They are common incidental findings in chronic inflammatory pulmonary diseases. They can also be found in normal lung parenchyma and as one part of the continuum known as diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. In many cases, they ...
Han Eon Chul EC Department of Pediatric Surgery, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University College of Medicine, Seoul, - - 2014
Gastrointestinal (GI) hemangiomas are relatively rare benign vascular tumors. The choice of an appropriate diagnostic method depends on patient age, anatomic location, and presenting symptoms. However, GI hemangiomas are not a common suspected cause of GI bleeding in children because of their rarity. Based on medical history, laboratory results, and ...
Genç Mine M Department of Obstetric & Gynecology, Şifa University, Faculty of Medicine, İZMİR, - - 2014
Malignant transformation of a benign cystic teratoma of the ovary is only rarely seen. A review of the English literature revealed no reports of a malignant melanoma developing from concurrent primary endometrial carcinoma and ovarian cystic teratoma. We report herein a 54-year-old nulliparous woman who underwent total abdominal hysterectomy and ...
Davidov Tomer T Division of General Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ. Electronic address: - - 2014
Thyroid nodules are present in 19%-67% of the population and carry a 5%-10% risk of malignancy. Unfortunately, fine-needle aspiration biopsies are indeterminate in 20%-30% of patients, often necessitating thyroid surgery for diagnosis. Numerous DNA microarray studies including a recently commercialized molecular classifier have helped to better distinguish benign from malignant ...
Carter Cordelia W CW Departments of *Orthopaedic Surgery ‡Radiology, Boston Children's Hospital †Harvard Medical School §Boston Children's Hospital, Boston, - - 2014
Although it has been postulated that injury to the proximal femoral physis results in the formation of a cam lesion, a clear causal association has not been established. The purpose of this study was to investigate the relationship between the physis and the cam lesion. Our hypotheses were that (1) ...
Falorni Alberto A Section of Internal Medicine and Endocrine and Metabolic - - 2014
Autoimmmune hypophysitis (AH) is the consequence of an immune-mediated inflammation of pituitary gland. The initial pituitary enlargement, secondary to infiltration and oedema, can evolve to remission, for spontaneous or pharmacological resolution of the inflammation, or evolve to progressive diffuse destruction with gland atrophy for fibrotic replacement, thus leading to various ...
Chang Stephanie T ST Department of Radiology, Stanford University School of Medicine, Stanford, CA; Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, - - 2013
Primary gastrointestinal (GI) lymphoma most often arises from stomach, small bowel, or colon. The 2 most common subtypes of primary GI lymphoma include low-grade mucosa-associated lymphoid tissue lymphoma, strongly associated with Helicobacter pylori infection, and high-grade diffuse, large B-cell lymphoma. Primary GI lymphoma demonstrates a myriad of imaging manifestations that ...
Tashjian Randy - - 2013
Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma of adults, but its presence in the breast is rare. We report a case of primary inflammatory MFH in a 72-year-old Caucasian female with no previous medical history and no prior radiation exposure. She presented with a palpable mass ...
Martini Maurizio - - 2013
The inflammatory fibroid polyp (IFP) is a benign lesion occurring in the digestive tract, mostly in the stomach and small bowel, composed of fibrovascular tissue infiltrated by inflammatory cells including eosinophils and mastocytes. Its pathogenesis has been controversial (reactive versus neoplastic). The recent finding of mutations in platelet-derived growth factor ...
Yamamoto Yasuhiro - - 2013
The purpose of this study was to examine the usefulness of cross-table view in the clinical diagnosis of cam-type femoroacetabular impingement (FAI). We measured the α angles on radiographs taken in cross-table lateral view in 39 hips with cam-type FAI and compared with those measured in 45 control hips. Alpha ...
Haugarvoll Kristoffer - - 2013
ABSTRACT: BACKGROUND: Correct diagnosis is pivotal to understand and treat neurological disease. Herein, we report the diagnostic work-up utilizing exome sequencing and the characterization of clinical features and brain MRI in two siblings with a complex, adult-onset phenotype; including peripheral neuropathy, epilepsy, relapsing encephalopathy, bilateral thalamic lesions, type 2 diabetes ...
Khalil Ashraf - - 2013
Aims. Hepatocellular carcinoma is one of the most aggressive malignant tumors and has limited treatment options. Needle-guided biopsies have been utilized as a tool to diagnose malignant focal hepatic lesions. These techniques are discouraged because of their complications. Nowadays, alpha fetoprotein is the most widely used tumor marker for screening ...
O'Connell J E - - 2012
BACKGROUND: Giant cell granulomas (GCGs) are benign tumours of the jaws of unknown aetiology. Aggressive lesions are difficult to manage and demonstrate a tendency to recur after surgical curettage. In the early 1980s, interferon alpha-2a was found to inhibit angiogenesis through a series of laboratory experiments and was subsequently used ...
Willder Jennifer M - - 2012
Alpha-fetoprotein (AFP)-producing primary lung tumours are rare; we present the first case of an AFP-producing lung tumour with metastasis to testes. The patient, a 72-year-old man, presented with a history of flu-like symptoms and abdominal pain. On examination he had a hard, tender left scrotal mass. Imaging showed a 4.4-cm ...
- - 2012
Detailed imaging studies of gas cysts in the intestinal mucosa (pneumatosis cystoides intestinalis) have been reported in around 20 patients taking acarbose, miglitolor voglibose, i.e. intestinal alpha-glucosidase inhibitors used as hypoglycaemic agents. Almost all the patients had nonspecific abdominal symptoms such as abdominal pain, abdominal distension, rectal bleeding or loss ...
Cambier Jean-François - - 2012
Glomerular diseases occurring in the course of malignancies remain rare. Diverse glomerular lesions can be observed in a variety of neoplasms and involve different pathophysiologic links between the glomerulopathy and the cancer. The pathophysiology of solid tumor-associated glomerulopathies remains obscure, whereas in hematologic malignancy-induced paraneoplastic glomerulopathies, a molecular link can ...
Jiang Jingjing - - 2012
The occurrence of a solitary plasmacytoma in the conjunctiva is unusual. This relatively uncommon neoplastic disorder occurs more frequently in other organs and is derived from B-lymphocytes. In the present study the case of a 17-year-old female, who had a lesion of the lower fornix conjunctiva in the left eye, ...
Mercan Selçuk - - 2012
A 29-year-old female patient with an isolated hydatid cyst in the lower pole of the left kidney presented with a history of weight loss and cloudy, foul-smelling urine. Laparoscopic partial nephrectomy was performed, at which the cyst was removed en bloc. On the fifth postoperative day, she was discharged without ...
Dimopoulou C - - 2012
A plasmocytoma involving the pituitary gland is an extremely rare entity, with approximately 22 cases of solitary myeloma or multiple myeloma presenting with sellar mass reported in the literature so far.Here, we report the case of a 71-year-old female patient affected by an extramedullary IgG-lambda multiple myeloma presenting as a ...
Shao Zhi-Qiang - - 2012
Abstract Objective.The aim of this study was to report the authors' experience with percutaneous intrarenal marsupialization of symptomatic peripelvic renal cysts. Material and methods. Thirty-one patients (16 male and 15 female, with a mean age of 49 years) with a peripelvic renal cyst associated with chronic flank or lumbar pain ...
De Carli Claudio - - 2012
Renal hydatid disease is a rare pathological condition in children. Hydatid cyst of the kidney corresponds to 2-4% of all hydatid disease cases. Minimally invasive techniques have been used in the treatment of renal hydatid cysts but surgical experience is limited. We report a 10-year-old patient with a left renal ...
Wen Jinghua - - 2012
Potential occupational arsenic exposure is a significant problem in smelting plants. The metabolites containing arsenic with an oxidation of +3 have been considered more cytotoxic and genotoxic than their parent inorganic species. The current study examined the capacity of arsenic methylation and its risk on skin lesions. The primary aim ...
Menogue Stuart R - - 2012
Study Type - Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Biopsy of incidentally detected small renal masses is a safe and accurate method of determining benign from malignant lesions. Renal biopsy identifies over one quarter of cases as benign; however, ...
Ahmad Sarfraz - - 2012
Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? The idea of using photosensitizing agents to enhance visualization of cancer tissue dates back to 1900. 5-Aminolevulinic acid (5-ALA) was first suggested for photodynamic diagnosis (PDD) of transitional cell cancer ...
Pogrel Anthony M - - 2012
This article will review current thoughts with regard to the etiology, histopathology, diagnosis, and management of giant cell lesions of the jaws. It will attempt to point out the differences between these lesions and giant cell lesions elsewhere in the body and also the current techniques for medical management of ...
Loftus Hannah - - 2013
Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely. In this article, we discuss the major causes of renal cysts in children and adults with a particular focus on the most ...
Sathiyamoorthy Srividya - - 2012
Malignant melanoma has an unusual predilection for metastasis to the small bowel, sometimes several years after the original diagnosis. In patients who have had a cystoprostatectomy followed by an ileal conduit, metastatic melanoma to the ileal conduit can present in urine cytology. We present a rare case of metastatic malignant ...
Schindler Katja - - 2012
Primary melanoma of the urinary bladder is a rare subentity of melanoma. The same applies for melanoma of the rhabdoid histopathologic phenotype. A female patient was initially diagnosed with melanoma of unknown origin caused by macroscopic lymph node metastasis in the left inguinal and parailiacal regions. Because of the extent ...
Sidana Abhinav - - 2012
Nephrogenic adenoma (NA) is a rare benign metaplastic lesion of the urothelial tract that arises as a response to injury and chronic inflammation. Although the most common site for NA is the bladder, it can occur in any part of urinary tract lined by urothelium. NA can mimic minor variants ...
Campo G - - 2012
Transitional cell carcinoma of the bladder is a rare entity in childhood. We report on a 9-year-old girl with transitional cell carcinoma of the bladder who presented with gross hematuria. Ultrasonography revealed a papillary lesion in the bladder, and the diagnosis was confirmed by cistoscopy. Complete transurethral resection of the ...
Oudart Jean-Baptiste - - 2012
Multiple myeloma (MM) is a hematologic malignancy most frequently preceded by a transient state called "pre-myeloma", whose main representatives are the Monoclonal Gammopathy of Undetermined Significance (MGUS) and asymptomatic MM. The biologist has an important role in the diagnosis of monoclonal gammopathy, from initial diagnosis to monitoring. Many national and ...
Cevik Muazez - - 2012
Patients with a vaginal mass (large Bartholin's duct cyst) associated with a contralateral renal cyst and hydroureteronephrosis are unable to urinate. While occasionally seen in adults, Bartholin's duct cyst is rare in neonates. The origins of Bartholin's and Gartner's cysts can be traced to the mesonephric duct. Given the rarity ...
Zhu Bing - - 2012
Micropapillary urothelial carcinoma (MPUC) is a rare subtype of urothelial carcinoma (UC) with an aggressive clinical course. The cytomorphologic features of MPUC in urine cytology have not been well described. In this study, 23 urine specimens (11 voided urines and 12 bladder washings) from 23 patients with MPUC on follow-up ...
Chrysikos Dimosthenis - - 2012
Mucinous tubular and spindle cell carcinoma (MTSC) is a rare and newly described type of renal cell carcinoma (RCC) with relatively indolent behavior. Although there are small series of this clinical entity in the literature, its histogenetic origin or line of differentiation remains unclear. A 67-year-old woman was hospitalized for ...
Deb Prabal - - 2012
PURPOSE: Adrenal haemangioblastoma presenting clinically as pheochromocytoma is a rare manifestation of extraneural haemangioblastoma. We present an unusual case of von Hippel-Lindau (VHL) disease that had adrenal and cerebellar haemangioblastoma with multiple renal cysts, and a review of the literature. METHODS: Unlike the usual manifestations of secondary polycythemia or increased ...
Whitworth Scott A - - 2012
Clear cell adenocarcinomas (CCAs) of the lower urinary tract are uncommon neoplasms that may present in routinely processed urinary cytology specimens. There is only limited discussion of the features of CCA of the lower urinary tract in the cytology literature. The authors report a series of 3 cases of this ...
Nason Gregory J - - 2012
Abstract Secondary tumours of the penis are rare; they most commonly arise from the prostate and the bladder. These lesions are often associated with disseminated malignancy and have a poor prognosis, with a 6-month mortality of up to 80% reported. Penile metastases have a variety of clinical manifestations including incidental ...
Taylor Amanda R - - 2012
A 10 yr old domestic longhair presented with a 2.5 mo history of recurrent hematuria. Abdominal ultrasound examination demonstrated a thickened urinary bladder, abdominal lymphadenopathy, and a thickened and rounded spleen. Cytologic examination of fine-needle aspirate samples revealed Histoplasma capsulatum organisms in the urinary bladder wall and spleen. The cat ...
Suzuki Kenjiro - - 2012
Arteriovenous malformations (AVMs) of the pelvis are relatively rare and difficult to treat because of multiple and extensive feeding vessels. We report the case of a 69-year-old male with pelvic congenital AVM that was detected during tests for dysuria. He visited our hospital complaining of voiding difficulty. Digital rectal examination ...
Brunocilla Eugenio - - 2012
Renal leiomyomas are rare benign tumours of the kidney originating from muscle cells. They are usually found by an autopsy, whether the patient is asymptomatic or has symptoms (i.e., abdominal/flank pain, hematuria, palpable mass). Today the widespread use of ultrasonography and computed tomography has increased the detection of clinically asymptomatic ...
Chen Ying-Bei - - 2012
Context.-Cystic lesions of the kidney may be accompanied by a range of neoplasms with distinct prognoses and future risks of developing additional tumors. In addition, some renal tumors, with or without accompanying renal cysts, may show a prominent cystic component. In the adult population, neoplasms occurring in a background of ...
Kudva Ranjini - - 2012
Mullerianosis of the urinary bladder is a rare and morphologically complex tumor-like lesion, composed of several types of mullerian lesions like endometriosis, endocervicosis, and endosalpingiosis. This disease occurs in women of reproductive age group. Implantative and metaplastic origins have been suggested in the pathogenesis.
Alexiev Borislav A - - 2012
Nephrogenic adenoma (NA) is an uncommon and intriguing lesion in the urinary tract. The pathogenesis of NA is not entirely clear. NA was considered to be a metaplastic process of the urothelium in response to chronic irritation of the urinary tract. However, recent evidence has shown that NA is not ...
Garza-Leon Manuel M Instituto para Preservación de la Visión, Destellos de Luz I.B.P, Ruperto Martínez # 1317 Pte., Col. Centro, Monterrey, Nuevo León, 64000, Mexico, - - 2012
The purpose of this study is to report a case of bilateral nodular scleritis in a patient with final diagnosis of IgA nephropathy. This is an observational case report. A male patient, 42 years old, presented with a bilateral nodular scleritis and OD sclerokeratitis. He had a previous history of acute ...
Green Ruth A R - - 2012
The imaging features and histology of two cases of non-neurogenic intraneural malignancy - an epithelioid sarcoma and myeloma - are described. These cases are important reminders that not all nerve tumours are of neural origin and also show the crucial importance of a robust multidisciplinary approach to achieve the correct ...
Rule Andrew D AD Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA. - - 2012
The presence of a few renal cysts is considered of little relevance in healthy adults, although acquired renal cystic disease occurs in advanced kidney failure. The objective of this study was to detail renal cystic and solid lesions and identify any association with clinical characteristics. Clinical-pathologic correlation. Potential kidney donors ...
Hirt-Minkowski P - - 2012
Urinary CXCL10 is a promising noninvasive biomarker for tubulo-interstitial allograft inflammation, but its diagnostic characteristics have not been assessed in a real-life setting. We investigated urinary CXCL10 in 213 consecutive renal allograft recipients having 362 surveillance biopsies at 3/6 months and 80 indication biopsies within the first year posttransplant. Allograft ...
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