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Yorita Kenji - - 2014
Ganglioneuroma is a rare tumor in the posterior mediastinum; fat-containing ganglioneuromas are rarely reported. The present case report documents a brown fat-containing, posterior mediastinal ganglioneuroma, which has not been reported previously. Radiological examination, in particular 18F-2-fluoro-2-deoxyglucose-positron emission tomography, suggested that the tumor had low-grade malignant potential. This led to uncertainty ...
Zhuang K D KD Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore. Electronic address: - - 2014
Superficial soft-tissue lesions are frequently encountered by radiologists in everyday practice. Characterization of these soft-tissue lesions remains problematic, despite advances in imaging. By systematically using clinical history, anatomical location, and signal intensity characteristics on MRI images, one can determine the diagnosis for the subset of determinate lesions that have characteristic ...
Preibsch Heike H University Department of Radiology Diagnostic and Interventional Radiology, Tübingen, Germany - - 2014
Published national and international guidelines and consensus meetings on the use of vacuum-assisted biopsy (VAB) give different recommendations regarding the required numbers of tissue specimens depending on needle size and imaging method. To evaluate the weights of specimens obtained with different VAB needles to facilitate the translation of the required ...
Tay Ee Tein ET Departments of Emergency Medicine and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York USA. - - 2014
Soft tissue infections and angioedema from insect bites and stings may be difficult to differentiate by inspection. We present sonographic findings of 4 cases of soft tissue swelling from insect bites and stings suggestive of angioedema. Sonographic features of soft tissue angioedema consist of thickened subcutaneous tissue layers with multiple ...
Na Joo-Young JY From the *Forensic Medicine Division, Gwangju Institute, National Forensic Service, Jangseoung-gun; and †Department of Pathology, Chonnam National University Hwasun Hospital, Hwasun-gun, Jeollanam; and ‡Department of Forensic Medicine, Chonnam National University Medical School, Gwangju, Republic of - - 2014
Pineal cysts are usually asymptomatic; however, they may rarely cause symptoms such as chronic headache, paroxysmal headache with gaze paresis, postural syncope, loss of consciousness, and sudden death. A 30-year-old woman with no specific medical history except chronic headache was found collapsed in a public toilet per se. Postmortem examination ...
Ruiz-Salmerón Rafael J RJ Endovascular Unit, Hospital Virgen Macarena, Avda Dr Fedriani no. 3, 41009 Seville, Spain. - - 2014
We report a subacute bioresorbable scaffold thrombosis caused by stent collapse into a heavily calcified lesion.
Okani Chukwudi O - - 2014
Germ cell neoplasms which have the potentials of differentiating along somatic cell lines are regarded as teratomas. They are mature teratomas when tissues are fully differentiated and immature teratomas when primitive or immature tissue elements are present. In this retrospective study, we analyzed all the renal biopsies submitted to the ...
Banovic F F Department of Clinical Sciences, NC State University, College of Veterinary Medicine, Raleigh, NC, USA Center for Comparative Medicine and Translational Research, NC State University, College of Veterinary Medicine, Raleigh, NC, - - 2014
Canine toxic epidermal necrosis (TEN), a rare and life-threatening cutaneous drug reaction, traditionally has been described as full-thickness devitalization of the epidermis with minimal dermal inflammation; however, few reports detail the histologic findings. We characterize the clinical features and histologic variations of 3 canine TEN patients. Clinically, irregular erythematous and ...
Rerknimitr Pawinee P Dermatology Unit, Department of Medicine, Chulalongkorn University, Bangkok, - - 2014
Familial comedones is a rare autosomal dominant disorder characterized by thousands of comedones developing in teens. Some pits or inflammatory lesions may coexist. Only 32 patients from three families have previously been reported. We report herein 12 cases in two unrelated families with familial comedones. Clinical manifestations among members in ...
Fussell Jacqueline Nicole - - 2014
Malignant melanoma is responsible for more than three-fourths of skin cancer deaths in the United States. Melanomas presenting on acral surfaces are frequently misdiagnosed initially, leading to progression of disease and worse prognosis. This case is presented to reinforce the significance of careful physical examination and early biopsy of atypical ...
Pekmezci Melike - - 2014
Central nervous system hemangiopericytoma (HPC) is an uncommon extraaxial tumor with controversial terminology, histogenesis, and grading. Herein, we report a unique example in a 64-year-old woman with a 3.2 cm extra-axial right frontal lobe mass. Histologic sections showed an HPC with increased mitotic activity and elevated proliferation index, interspersed with ...
McCourt C C Department of Dermatology, Belfast Health and Social Care Trust, Northern Ireland; Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen's University Belfast, Northern - - 2014
To investigate the association between post-diagnostic beta-blocker usage and risk of melanoma-specific mortality in a population-based cohort of malignant melanoma patients. Incident malignant melanoma patients diagnosed between 1998 and 2010 were identified within the UK Clinical Practice Research Datalink and confirmed using cancer registry data. Malignant melanoma patients with a ...
Shital Patil P Pulmonary Medicine, MIMSR Medical College Latur, Latur, Maharashtra, India, - - 2014
Lung cancer is the leading cause of cancer deaths around the world. Globally, lung cancer is the largest contributor to new cancer diagnosis and to death from cancer. Various conventional diagnostic techniques (CDTs) such as endobronchial forcep biopsy (FB), bronchial washing (BW) and bronchial brushing (BB), and transbronchial needle aspiration ...
Vanderschueren S - - 2014
Background: Few data exist on the contemporary prognosis of patients presenting with fever of unknown origin (FUO). Methods: The data of 436 adult immunocompetent patients presenting with FUO between 2000 and 2010 and followed for at least 6 months were analyzed, with a focus on FUO-related deaths. The following variables ...
Tashiro Jun J DeWitt-Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, - - 2014
Malignant melanomas are the most common skin cancer in the pediatric population. Melanoma incidence is extremely low in infants, and metastatic disease is even less common. We present the case of an 11-month-old girl who presented with a non-pigmented lesion that progressed to an ulcerated lesion. Pathology was found to ...
Patel Junaid J CRY Centre for Cardiac Pathology, National Heart and Lung Institute, Imperial College, London, - - 2014
Sudden cardiac death (SCD) accounts for 50% of cardiovascular mortality with an estimated annual toll of 300 000 deaths in the USA and 60 000 deaths in the UK. Benign primary cardiac tumours are extremely rare, and although many of these entities are clinically silent, a few can cause significant ...
Balois Thibaut T 1] Laboratoire de Physique Statistique, Ecole Normale Supérieure, UPMC Univ Paris 06, Université Paris Diderot, CNRS, 24 rue Lhomond, 75005 Paris, France [2] Institut Universitaire de Cancérologie, Faculté de médecine, Université Pierre et Marie Curie-Paris 6, 91 boulevard de l'hôpital, 75013 Paris, - - 2014
Melanoma is a solid tumour with its own specificity from the biological and morphological viewpoint. On one hand, numerous mutations are already known affecting different pathways. They usually concern proliferation rate, apoptosis, cell senescence and cell behaviour. On the other hand, several visual criteria at the tissue level are used ...
Fulawka Lukasz L Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, ul, Borowska 213, 50-556 Wroclaw, Poland. - - 2014
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with an incidence rate of 1 to 2 per million person-years. ACC most commonly arises sporadically, but may be associated with familial tumour syndromes. Clinical symptoms are mainly related to an excess of steroid hormones. We present an unusual case of adrenocortical ...
Ishida Mitsuaki M Department of Clinical Laboratory Medicine, Shiga University of Medical Science Shiga, Japan ; Division of Diagnostic Pathology, Shiga University of Medical Science Shiga, - - 2014
Patients with sarcoidosis have a high risk of development of malignant lymphoma, and this association was coined the term "sarcoidosis-lymphoma syndrome". Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a distinct clinicopathological entity, and the stomach is the most common site. The occurrence of this type of ...
Higgins H William HW 2nd Department of Dermatology, Section of Cutaneous Oncology and Dermatologic Surgery, Yale University School of Medicine 40 Temple Street 5A, New Haven, CT 06510 - - 2014
Melanoma is a malignancy of melanocytes or pigment-producing cells located predominantly in the skin. It is less common than other skin cancers but causes the greatest number of skin cancer-related deaths worldwide. The incidence of melanoma continues to increase and early detection is the most promising means of decreasing morbidity ...
Gemenetzis Georgios G 4th Department of Surgery, Medical School of Athens, Attikon University Hospital, Rimini 1, Attiki, 12462 Athens, - - 2014
Extrarenal angiomyolipoma (AML) is an extremely uncommon lesion, accounting for less than 9% of all angiomyolipomas. We present a previously unreported case of a rarely located gigantic extrarenal angiomyolipoma at the posterolateral chest wall of a 35-year-old woman. Clinically, the lesion had all the characteristics of a benign tumor, being ...
H K Sharathkumar S Associate Professor, Department of Pathology, Mysore Medical College and Research Institute , Mysore, India - - 2013
Eccrine porocarcinoma is an extremely rare malignancy of the eccrine sweat gland. It is believed to arise from the intra-epithelial portion of eccrine sweat glands. It can either arise de novo or it can develop in a long standing eccrine poroma. It often occurs in the elderly, with the mean ...
Pecorella Irene - - 2013
Objective: To report a case of palpebral solitary fibrous tumour (SFT). Clinical Presentation and Intervention: An elderly man presented with a slow-growing painless mass in the lower conjunctival fornix in the left eye. The lesion was excised and it measured 0.9 cm in maximum diameter. The microscopic features were characteristic ...
Teixeira Tarso Felipe - - 2013
Melanoma is a malignant neoplasm occurring in several animal species, and is the most frequently found tumor in the oral cavity in dogs. Melanomas are classified into two types: melanotic and amelanotic. Prior research suggests that human amelanotic melanomas are more aggressive than their melanotic counterparts. This study evaluates the ...
Benoiton L A - - 2013
Colloid cysts of the third ventricle are rare benign tumours that can present as symptomatic hydrocephalus or be an incidental finding on imaging. This report presents familial colloid cysts found in a mother and daughter. Prior examples of familial colloid cysts are also reviewed and suggestions regarding the mode of ...
Korkmaz D - - 2013
The aim of the study was to evaluate apoptosis through regulation of Bcl-2, Bax and Mcl-1 proteins by comparing their expressions in endometriotic cyst lesions and the endometrium of the patients with moderate to severe endometriosis. This is a cross-sectional study of 30 women in reproductive age with a clinical ...
Demestre Maria - - 2013
Neurofibromatosis type 1 (NF1) is an inherited genetic disease affecting 1 in 3,500 individuals. A prominent feature of NF1 is the formation of benign tumours of the peripheral nerve sheath (neurofibromas). However, these can become malignant and form highly metastatic malignant peripheral nerve sheath tumours (MPNST), which are usually fatal ...
Harer W Benson WB Jr Seattle, WA, - - 2013
AB Granville was a pioneer obstetrician and gynaecologic surgeon who performed the world's first myomectomy and the first ovariotomy in England. He also performed the first scientific autopsy of an Egyptian mummy, discovering the oldest known ovarian tumour. He thought it was malignant and caused her death from 'ovarian dropsy'. ...
Dzwierzynski William W WW Department of Plastic Surgery, Medical College of Wisconsin, 8700 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA. - - 2013
The incidence of melanoma is increasing worldwide. Melanomas represent 3 percent of all skin cancers but 65 percent of skin cancer deaths. Melanoma is now the fifth most common cancer diagnosed in the United States. Excisional biopsy should be performed for lesions suspicious for melanoma. The pathologist's report provides essential ...
Jung Jae Gu - - 2013
Background/Aims: Benign biliary strictures (BBSs) have been endoscopically managed with plastic stent placement. However, data regarding fully covered self-expandable metal stents (FCSEMSs) in BBS patients remain scarce in Korea. Methods: We report a case of primary mucosa-associated lymphoid tissue (MALT) lymphoma in the esophagus that manifested as a large submucosal ...
Quatrale Anna Elisa - - 2013
Antivascular approaches aim to cause rapid and catastrophic shutdown in the vascular function of the tumour, leading to extensive tumour cell death. Tumour vascular disrupting agents (VDAs) are a new class of cancer therapies that target the existing vasculature of tumours, taking advantage of the relative instability of tumour vasculature ...
Teresiak-Mikołajczak Ewa E Department of Dermatology, Poznan University of Medical Sciences, Poland. Head: Prof. Zbigniew Adamski MD, - - 2013
We report a case of a woman with diffuse large B-cell lymphoma (DLBCL). Primary cutaneous lymphomas (PCLs) represent distinct clinical and histopathologic subtypes of extranodal T- and B-cell lymphomas. Cutaneous B-cell lymphomas comprise 20-25% of all primary cutaneous lymphomas. The patient presented an erythematous tumour mass of the left nasolabial ...
Andersen Christen Lykkegaard CL Department of Hematology, Roskilde University Hospital, Denmark; The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, - - 2013
Eosinophilia may represent an early paraclinical sign of hematological malignant disease, but no reports exist on its predictive value for hematological malignancies. From the Copenhagen Primary Care Differential Count (CopDiff) Database, we identified 356,196 individuals with at least one differential cell count (DIFF) encompassing the eosinophil count during 2000-2007. From ...
Tong Wei-Dong WD Gastric and Colorectal Division, Department of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China. - - 2013
Anorectal malformations (ARM) are common anomalies in neonates. Diagnostic and therapeutic delays in the management of ARM may lead to colonic perforation, and even death. Physical examination of the perineum is often sufficient to diagnose ARM in neonates. Notwithstanding, delayed diagnosis of ARM has become increasingly familiar to surgeons, as ...
Gupta Nitin K NK Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, - - 2013
Cord colitis syndrome (CCS) is a recently described diarrheal illness of uncertain pathogenesis that affects recipients of umbilical cord blood transplant and is associated with negative cultures. CCS exhibits a peculiar histopathologic appearance, as it commonly manifests as granulomatous inflammation involving the upper and lower gastrointestinal tract, with features of ...
Sini Germana - - 2013
Primary dermal melanoma (PDM) is a recently described clinical entity accounting for less than 1% of all melanomas. Histologically, it is located in the dermis or subcutaneous tissue, and it shows no connections with the overlying epidermis. The differential diagnosis is principally made along with that of metastatic cutaneous melanoma. ...
Hargis Ann M - - 2013
OBJECTIVES: To describe the clinical, histopathological and immunohistochemical lesions and the response to therapy of a novel skin disease in four dogs, and to compare the lesions with those of other similar conditions. METHODS: Clinical lesions, the histopathological findings in skin biopsy samples, immunohistochemistry for CD3 and cleaved caspase-3 and ...
Augsburger James Jay - - 2013
Determine whether cytopathologic classification of melanocytic uveal tumors evaluated by fine-needle aspiration biopsy (FNAB) is a significant prognostic factor for death from metastasis. Retrospective analysis of cases of clinically diagnosed uveal melanoma evaluated by fine-needle aspiration biopsy from 1980 to 2006. Main outcome evaluated was death from metastasis. Associations between ...
Pathak T B TB B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, - - 2013
A solitary fibrous tumour is an unusual spindle cell neoplasm. It frequently arises from the serosal surface of pleural cavity but has recently been described in diverse extrapleural sites. Urogenital localization is rare and only 36 cases of solitary fibrous tumours of the kidney have been described on published report. ...
Bandarchi Bizhan - - 2013
Malignant melanoma is one of the most aggressive malignancies in humans and is responsible for 60-80% of deaths from skin cancers. The 5-year survival of patients with metastatic malignant melanoma is about 14%. Its incidence has been increasing in the white population over the past two decades. The mechanisms leading ...
Park Seong Hwan - - 2013
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder, characterized by papular skin lesions and cutaneous laxity caused by fragmentation and mineralization of elastic fibers. Although vascular and retinal aspects of this disease and their associated complications are well characterized, few authors have focused on the increased incidence of epilepsy in ...
Kleinfeld Kirk - - 2013
We report a patient with a rare primary signet-ring cell carcinoma of the transverse colon with secondary leptomeningeal carcinomatosis. The only presenting and persistent symptom was worsening headache for 6weeks until death. There were no other neurological, constitutional, or gastrointestinal symptoms. The primary tumor was detected by CT scan and ...
Polat Ahmet Veysel - - 2013
Anterior sacral meningocele (ASM) is a rare congenital anomaly, characterized by herniation through a defect in the anterior aspect of the sacrum. We reported a case of ASM associated with neurofibromatosis, which was mimicking a complex ovarian cyst in ultrasonography. ASM can easily be misdiagnosed as an ovarian cyst and ...
Verma Ritu - - 2013
Primitive neuroectodermal tumour (PNET) is a neural crest tumour derived from neuroectoderm. Renal PNET is a very rare tumour occurring during childhood or adolescence. We report two cases of PNET involving kidney in adults. Presenting signs and symptoms include abdominal/flank pain and/or haematuria. Microscopy reveals the tumour consisted of small ...
Demirag F - - 2013
Adenosquamous carcinoma of the lung involves both adenocarcinoma and squamous cell carcinoma, each comprising at least 10% of the tumor. Atypical adenomatous hyperplasia (ADH), bronchiolar columnar cell dysplasia (BCCD), basal cell dysplasia (BCD), columnar cell dysplasia (CCD), bronchial epithelial dysplasia with transitional differentiation (BEDT) and squamous dysplasia (SD) are preinvasive ...
Penumatsa Narendra Varma - - 2013
Radicular cyst is the most common odontogenic cystic lesion of inflammatory origin. It is also known as periapical cyst, apical periodontal cyst, root end cyst, or dental cyst. It arises from epithelial residues in the periodontal ligament as a result of inflammation. The inflammation usually follows the death of dental ...
Mithra R - - 2013
One of the major health hazards which is prevalent and dangerous is the dengue fever which causes the death of many people. This may be associated with a variety of mucocutaneous manifestations which may be of help in early diagnosis. Many biochemical assays and hematological investigations may aid in the ...
Venugopal M - - 2013
Malignant melanoma of the oral cavity is a rare lesion, with an incidence of about 0.2% to 0.8% of all melanomas. Melanoma of tongue is still rarer and represents less than 2% of oro-nasal melanoma cases. We report a rare case of amelanotic melanoma of the tongue in a young ...
Wochna Katarzyna - - 2013
The authors present a case of malignant hyperthermia. The article discusses the death of a 4-year old boy who appeared to be perfectly healthy and underwent dental treatment under general anesthesia. The procedure went well at the beginning, but suddenly complications developed, such as cardiac rhythm disorders and increased body ...
Rahman Farzan - - 2013
Pericoronal tissue is the soft tissue located between the bony crypt and the impacted tooth, which is histologically composed of fibrous connective tissue and is usually lined by the reduced enamel epithelium. Increased epithelial cell proliferation in the pericoronal tissue is associated with pathological changes such as development of an ...
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