Search Results
Results 1 - 50 of 1889
1 2 3 4 5 6 7 8 9 10 >
Pekmezci Melike - - 2014
Central nervous system hemangiopericytoma (HPC) is an uncommon extraaxial tumor with controversial terminology, histogenesis, and grading. Herein, we report a unique example in a 64-year-old woman with a 3.2 cm extra-axial right frontal lobe mass. Histologic sections showed an HPC with increased mitotic activity and elevated proliferation index, interspersed with ...
McCourt C C Department of Dermatology, Belfast Health and Social Care Trust, Northern Ireland; Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen's University Belfast, Northern - - 2014
To investigate the association between post-diagnostic beta-blocker usage and risk of melanoma-specific mortality in a population-based cohort of malignant melanoma patients. Incident malignant melanoma patients diagnosed between 1998 and 2010 were identified within the UK Clinical Practice Research Datalink and confirmed using cancer registry data. Malignant melanoma patients with a ...
Shital Patil P Pulmonary Medicine, MIMSR Medical College Latur, Latur, Maharashtra, India, - - 2014
Lung cancer is the leading cause of cancer deaths around the world. Globally, lung cancer is the largest contributor to new cancer diagnosis and to death from cancer. Various conventional diagnostic techniques (CDTs) such as endobronchial forcep biopsy (FB), bronchial washing (BW) and bronchial brushing (BB), and transbronchial needle aspiration ...
Vanderschueren S - - 2014
Background: Few data exist on the contemporary prognosis of patients presenting with fever of unknown origin (FUO). Methods: The data of 436 adult immunocompetent patients presenting with FUO between 2000 and 2010 and followed for at least 6 months were analyzed, with a focus on FUO-related deaths. The following variables ...
Tashiro Jun J DeWitt-Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, - - 2014
Malignant melanomas are the most common skin cancer in the pediatric population. Melanoma incidence is extremely low in infants, and metastatic disease is even less common. We present the case of an 11-month-old girl who presented with a non-pigmented lesion that progressed to an ulcerated lesion. Pathology was found to ...
Patel Junaid J CRY Centre for Cardiac Pathology, National Heart and Lung Institute, Imperial College, London, - - 2014
Sudden cardiac death (SCD) accounts for 50% of cardiovascular mortality with an estimated annual toll of 300 000 deaths in the USA and 60 000 deaths in the UK. Benign primary cardiac tumours are extremely rare, and although many of these entities are clinically silent, a few can cause significant ...
Balois Thibaut T 1] Laboratoire de Physique Statistique, Ecole Normale Supérieure, UPMC Univ Paris 06, Université Paris Diderot, CNRS, 24 rue Lhomond, 75005 Paris, France [2] Institut Universitaire de Cancérologie, Faculté de médecine, Université Pierre et Marie Curie-Paris 6, 91 boulevard de l'hôpital, 75013 Paris, - - 2014
Melanoma is a solid tumour with its own specificity from the biological and morphological viewpoint. On one hand, numerous mutations are already known affecting different pathways. They usually concern proliferation rate, apoptosis, cell senescence and cell behaviour. On the other hand, several visual criteria at the tissue level are used ...
Fulawka Lukasz L Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, ul, Borowska 213, 50-556 Wroclaw, Poland. - - 2014
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with an incidence rate of 1 to 2 per million person-years. ACC most commonly arises sporadically, but may be associated with familial tumour syndromes. Clinical symptoms are mainly related to an excess of steroid hormones. We present an unusual case of adrenocortical ...
H K Sharathkumar S Associate Professor, Department of Pathology, Mysore Medical College and Research Institute , Mysore, India - - 2013
Eccrine porocarcinoma is an extremely rare malignancy of the eccrine sweat gland. It is believed to arise from the intra-epithelial portion of eccrine sweat glands. It can either arise de novo or it can develop in a long standing eccrine poroma. It often occurs in the elderly, with the mean ...
Pecorella Irene - - 2013
Objective: To report a case of palpebral solitary fibrous tumour (SFT). Clinical Presentation and Intervention: An elderly man presented with a slow-growing painless mass in the lower conjunctival fornix in the left eye. The lesion was excised and it measured 0.9 cm in maximum diameter. The microscopic features were characteristic ...
Teixeira Tarso Felipe - - 2013
Melanoma is a malignant neoplasm occurring in several animal species, and is the most frequently found tumor in the oral cavity in dogs. Melanomas are classified into two types: melanotic and amelanotic. Prior research suggests that human amelanotic melanomas are more aggressive than their melanotic counterparts. This study evaluates the ...
Benoiton L A - - 2013
Colloid cysts of the third ventricle are rare benign tumours that can present as symptomatic hydrocephalus or be an incidental finding on imaging. This report presents familial colloid cysts found in a mother and daughter. Prior examples of familial colloid cysts are also reviewed and suggestions regarding the mode of ...
Korkmaz D - - 2013
The aim of the study was to evaluate apoptosis through regulation of Bcl-2, Bax and Mcl-1 proteins by comparing their expressions in endometriotic cyst lesions and the endometrium of the patients with moderate to severe endometriosis. This is a cross-sectional study of 30 women in reproductive age with a clinical ...
Demestre Maria - - 2013
Neurofibromatosis type 1 (NF1) is an inherited genetic disease affecting 1 in 3,500 individuals. A prominent feature of NF1 is the formation of benign tumours of the peripheral nerve sheath (neurofibromas). However, these can become malignant and form highly metastatic malignant peripheral nerve sheath tumours (MPNST), which are usually fatal ...
Harer W Benson WB Jr Seattle, WA, - - 2013
AB Granville was a pioneer obstetrician and gynaecologic surgeon who performed the world's first myomectomy and the first ovariotomy in England. He also performed the first scientific autopsy of an Egyptian mummy, discovering the oldest known ovarian tumour. He thought it was malignant and caused her death from 'ovarian dropsy'. ...
Dzwierzynski William W WW Department of Plastic Surgery, Medical College of Wisconsin, 8700 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA. - - 2013
The incidence of melanoma is increasing worldwide. Melanomas represent 3 percent of all skin cancers but 65 percent of skin cancer deaths. Melanoma is now the fifth most common cancer diagnosed in the United States. Excisional biopsy should be performed for lesions suspicious for melanoma. The pathologist's report provides essential ...
Jung Jae Gu - - 2013
Background/Aims: Benign biliary strictures (BBSs) have been endoscopically managed with plastic stent placement. However, data regarding fully covered self-expandable metal stents (FCSEMSs) in BBS patients remain scarce in Korea. Methods: We report a case of primary mucosa-associated lymphoid tissue (MALT) lymphoma in the esophagus that manifested as a large submucosal ...
Quatrale Anna Elisa - - 2013
Antivascular approaches aim to cause rapid and catastrophic shutdown in the vascular function of the tumour, leading to extensive tumour cell death. Tumour vascular disrupting agents (VDAs) are a new class of cancer therapies that target the existing vasculature of tumours, taking advantage of the relative instability of tumour vasculature ...
Teresiak-Mikołajczak Ewa E Department of Dermatology, Poznan University of Medical Sciences, Poland. Head: Prof. Zbigniew Adamski MD, - - 2013
We report a case of a woman with diffuse large B-cell lymphoma (DLBCL). Primary cutaneous lymphomas (PCLs) represent distinct clinical and histopathologic subtypes of extranodal T- and B-cell lymphomas. Cutaneous B-cell lymphomas comprise 20-25% of all primary cutaneous lymphomas. The patient presented an erythematous tumour mass of the left nasolabial ...
Tong Wei-Dong - - 2013
Anorectal malformations (ARM) are common anomalies in neonates. Diagnostic and therapeutic delays in the management of ARM may lead to colonic perforation, and even death. Physical examination of the perineum is often sufficient to diagnose ARM in neonates. Notwithstanding, delayed diagnosis of ARM has become increasingly familiar to surgeons, as ...
Andersen Christen Lykkegaard - - 2013
Eosinophilia may represent an early paraclinical sign of hematological malignant disease, but no reports exist on its predictive value for hematological malignancies. From the Copenhagen Primary Care Differential Count (CopDiff) Database, we identified 356.196 individuals with at least one differential cell count (DIFF) encompassing the eosinophil count during 2000-2007. From ...
Gupta Nitin K - - 2013
Cord colitis syndrome (CCS) is a recently described diarrheal illness of uncertain pathogenesis that affects recipients of umbilical cord blood transplant and is associated with negative cultures. CCS exhibits a peculiar histopathologic appearance, as it commonly manifests as granulomatous inflammation involving the upper and lower gastrointestinal tract, with features of ...
Sini Germana - - 2013
Primary dermal melanoma (PDM) is a recently described clinical entity accounting for less than 1% of all melanomas. Histologically, it is located in the dermis or subcutaneous tissue, and it shows no connections with the overlying epidermis. The differential diagnosis is principally made along with that of metastatic cutaneous melanoma. ...
Hargis Ann M - - 2013
OBJECTIVES: To describe the clinical, histopathological and immunohistochemical lesions and the response to therapy of a novel skin disease in four dogs, and to compare the lesions with those of other similar conditions. METHODS: Clinical lesions, the histopathological findings in skin biopsy samples, immunohistochemistry for CD3 and cleaved caspase-3 and ...
Augsburger James Jay - - 2013
Determine whether cytopathologic classification of melanocytic uveal tumors evaluated by fine-needle aspiration biopsy (FNAB) is a significant prognostic factor for death from metastasis. Retrospective analysis of cases of clinically diagnosed uveal melanoma evaluated by fine-needle aspiration biopsy from 1980 to 2006. Main outcome evaluated was death from metastasis. Associations between ...
Pathak T B TB B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, - - 2013
A solitary fibrous tumour is an unusual spindle cell neoplasm. It frequently arises from the serosal surface of pleural cavity but has recently been described in diverse extrapleural sites. Urogenital localization is rare and only 36 cases of solitary fibrous tumours of the kidney have been described on published report. ...
Bandarchi Bizhan - - 2013
Malignant melanoma is one of the most aggressive malignancies in humans and is responsible for 60-80% of deaths from skin cancers. The 5-year survival of patients with metastatic malignant melanoma is about 14%. Its incidence has been increasing in the white population over the past two decades. The mechanisms leading ...
Park Seong Hwan - - 2013
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder, characterized by papular skin lesions and cutaneous laxity caused by fragmentation and mineralization of elastic fibers. Although vascular and retinal aspects of this disease and their associated complications are well characterized, few authors have focused on the increased incidence of epilepsy in ...
Kleinfeld Kirk - - 2013
We report a patient with a rare primary signet-ring cell carcinoma of the transverse colon with secondary leptomeningeal carcinomatosis. The only presenting and persistent symptom was worsening headache for 6weeks until death. There were no other neurological, constitutional, or gastrointestinal symptoms. The primary tumor was detected by CT scan and ...
Polat Ahmet Veysel - - 2013
Anterior sacral meningocele (ASM) is a rare congenital anomaly, characterized by herniation through a defect in the anterior aspect of the sacrum. We reported a case of ASM associated with neurofibromatosis, which was mimicking a complex ovarian cyst in ultrasonography. ASM can easily be misdiagnosed as an ovarian cyst and ...
Verma Ritu - - 2013
Primitive neuroectodermal tumour (PNET) is a neural crest tumour derived from neuroectoderm. Renal PNET is a very rare tumour occurring during childhood or adolescence. We report two cases of PNET involving kidney in adults. Presenting signs and symptoms include abdominal/flank pain and/or haematuria. Microscopy reveals the tumour consisted of small ...
Demirag F - - 2013
Adenosquamous carcinoma of the lung involves both adenocarcinoma and squamous cell carcinoma, each comprising at least 10% of the tumor. Atypical adenomatous hyperplasia (ADH), bronchiolar columnar cell dysplasia (BCCD), basal cell dysplasia (BCD), columnar cell dysplasia (CCD), bronchial epithelial dysplasia with transitional differentiation (BEDT) and squamous dysplasia (SD) are preinvasive ...
Penumatsa Narendra Varma - - 2013
Radicular cyst is the most common odontogenic cystic lesion of inflammatory origin. It is also known as periapical cyst, apical periodontal cyst, root end cyst, or dental cyst. It arises from epithelial residues in the periodontal ligament as a result of inflammation. The inflammation usually follows the death of dental ...
Mithra R - - 2013
One of the major health hazards which is prevalent and dangerous is the dengue fever which causes the death of many people. This may be associated with a variety of mucocutaneous manifestations which may be of help in early diagnosis. Many biochemical assays and hematological investigations may aid in the ...
Venugopal M - - 2013
Malignant melanoma of the oral cavity is a rare lesion, with an incidence of about 0.2% to 0.8% of all melanomas. Melanoma of tongue is still rarer and represents less than 2% of oro-nasal melanoma cases. We report a rare case of amelanotic melanoma of the tongue in a young ...
Wochna Katarzyna - - 2013
The authors present a case of malignant hyperthermia. The article discusses the death of a 4-year old boy who appeared to be perfectly healthy and underwent dental treatment under general anesthesia. The procedure went well at the beginning, but suddenly complications developed, such as cardiac rhythm disorders and increased body ...
Rahman Farzan - - 2013
Pericoronal tissue is the soft tissue located between the bony crypt and the impacted tooth, which is histologically composed of fibrous connective tissue and is usually lined by the reduced enamel epithelium. Increased epithelial cell proliferation in the pericoronal tissue is associated with pathological changes such as development of an ...
Zamurovic M - - 2013
The case of a patient diagnosed and surgically treated for amelanotic malignant melanoma of the perineum, accompanied by several local relapses, metastases to iliac-femoral lymph nodes, and distant metastases to both lungs is presented. Survival, up to date, equals 12 years. Amelanotic malignant melanomas are very rare tumors. Perineal and ...
Kashiwagi Masayuki - - 2013
The erythematous patches and vesicles that are observed in coma patients, usually from an overdose of medication, are known as coma blisters. However, it is unknown whether the degenerated sweat gland is a necrosis or apoptosis. We immunohistochemically examined such skin lesions to investigate the characteristics and pathogenesis of the ...
Igarashi Tsutomu T Department of Ophthalmology, Nippon Medical - - 2013
Introduction: A case of mucosa-associated lymphoid tissue (MALT) lymphoma, the most frequent of the various conjunctival lymphoproliferative disorders, in which the initial biopsy was inconclusive but the second biopsy provided a definitive diagnosis, is reported. Case Report: A 26-year-old woman with a 3-month history of bilateral conjunctival swelling was referred ...
Lavezzi Wendy A - - 2012
A healthy 6-year-old boy developed lower extremity rigidity, trismus, and fever after playing in a splash pool. On arrival in the emergency department, he appeared to be seizing. An endotracheal tube was emergently placed using succinylcholine. Cardiac arrest followed. He could not be resuscitated. Postmortem genetic analysis found a novel ...
Jovanovic R - - 2012
(Full text is available at http://www.manu.edu.mk/prilozi). Pheochromocytomas and paragangliomas are rare neoplasms. Approximately 10% may present malignant behaviour. There are no reliable morphological signs of malignancy, except for the presence of metastasis. We performed morphological and immunohistochemical analysis on 15 pheochromocytomas and 5 paragangliomas aiming to find correlations between the ...
Lin Jingmei - - 2012
Histopathology assessment is crucial for the diagnosis of graft versus host disease (GVHD), as the presence of crypt apoptosis is the cardinal criterion required. However, crypt apoptosis is not limited to GVHD; it also occurs in other conditions such as infection, drug reaction, or inflammatory reactions unrelated to GVHD. To ...
Loreto C - - 2012
AIM: To investigate whether the apoptotic cascade is activated through the extrinsic pathway in epithelial lining and connective tissue of radicular cysts. METHODOLOGY: Fifteen radicular cysts were fixed in formalin, embedded in paraffin wax and processed for immunohistochemistry to evaluate the expression of polyclonal antibodies against Tumour necrosis factor-related apoptosis-inducing ...
Mar Victoria - - 2012
BACKGROUND: There is a growing body of evidence that nodular melanoma (NM), because of its association with increased growth rate and thickness at diagnosis, accounts for a substantial proportion of melanoma deaths. OBJECTIVE: We sought to assess the contribution of NM to melanoma deaths in comparison with other tumor subtypes. ...
Begeman L - - 2012
Intestinal volvulus was recognized as the cause of death in 18 cetaceans, including 8 species of toothed whales (suborder Odontoceti). Cases originated from 11 institutions from around the world and included both captive (n = 9) and free-ranging (n = 9) animals. When the clinical history was available (n = ...
Orgaz Jose L - - 2012
Metastatic cutaneous melanoma accounts for the majority of skin cancer deaths due to its aggressiveness and high resistance to current therapies. In order to efficiently metastasize, invasive melanoma cells need to change their cytoskeletal organization and alter contacts with the extracellular matrix and the surrounding stromal cells. Melanoma cells can ...
Park Sun-Young - - 2012
Primary malignant melanoma of the anterior mediastinum is extremely rare, accounting for 0.1-0.5% of all primary malignant neoplasms. These tumors may be mistakenly diagnosed as lymphomas, thymic carcinomas and malignant germ-cell tumors of the mediastinum. We describe two cases of primary malignant melanomas of the anterior mediastinum and report their ...
Ross Ian L - - 2012
Primary adrenal insufficiency (PAI) may be less prevalent in South Africa and specifically among blacks. There are a number of possible reasons for this, with under-diagnosis among South African blacks, being the most likely explanation. Deaths from undiagnosed PAI still occur. © 2012 Blackwell Publishing Ltd.
Antunes Armando A - - 2012
To evaluate the pattern of Ki-67, Bcl-2 and COX-2 expression in the glandular epithelium and stroma of malignant and benign endometrial polyps in postmenopause. A total of 390 postmenopausal women underwent surgical hysteroscopy; women with endometrial polyps were included. Polypoid lesions were histologically classified as benign, premalignant or malignant lesions. ...
1 2 3 4 5 6 7 8 9 10 >