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Sethi Varun - - 2012
ObjectiveCortical grey matter lesions are common in multiple sclerosis (MS), but usually not seen on MRI. The authors compared the performance of double inversion recovery (DIR, currently considered the best available imaging sequence for detecting cortical lesions) with phase-sensitive inversion recovery (PSIR, a sequence allowing much higher resolution scans to ...
Mohr David C - - 2012
This trial examined the efficacy of a stress management program in reducing neuroimaging markers of multiple sclerosis (MS) disease activity. A total of 121 patients with relapsing forms of MS were randomized to receive stress management therapy for MS (SMT-MS) or a wait-list control condition. SMT-MS provided 16 individual treatment ...
Martin Nancy - - 2012
The purpose of our study was to compare axial multiple-echo recombined gradient echo (MERGE) with axial T2-weighted fast spin-echo (FSE) imaging for the detection of multiple sclerosis (MS) lesions in the cervical spinal cord on MRI. Twenty-nine cervical spine MRI studies of patients with MS lesions and 29 control cases ...
Bluestein Katharine T - - 2012
Cortical lesions have recently been a focus of multiple sclerosis (MS) MR research. In this study, we present a white matter signal attenuating sequence optimized for cortical lesion detection at 7 T. The feasibility of white matter attenuation (WHAT) for cortical lesion detection was determined by scanning eight patients (four ...
Thakar Sumit - - 2012
Intracranial occurrence of a chloroma (myeloid sarcoma, MS) in the absence of a preceding hematological malignancy is unusual. We report the case of a 20-year-old man who presented with Garcin's syndrome of short duration. MRI revealed multiple extra-axial contrast enhancing lesions: two mirror lesions on the skull base, and one ...
Balashov Konstantin E KE Department of Neurology, UMDNJ, Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA. - - 2012
It is widely accepted that typical acute demyelinating lesions in relapsing-remitting multiple sclerosis (RRMS) exhibit vasogenic edema with increased diffusion, as demonstrated by an increased apparent diffusion coefficient on MRI. In contrast, acute ischemic lesions demonstrate cytotoxic edema with restricted diffusion. Recent reports have documented selected cases of acute demyelinating ...
Waldemarson Sofia S Department of Immunotechnology, Lund University, BMC D13, 221 84 Lund, Sweden. - - 2012
Epithelial ovarian carcinoma has in general a poor prognosis since the vast majority of tumors are genomically unstable and clinically highly aggressive. This results in rapid progression of malignancy potential while still asymptomatic and thus in late diagnosis. It is therefore of critical importance to develop methods to diagnose epithelial ...
Filli Lukas - - 2012
Background: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. MS lesions show a typical distribution pattern and primarily affect the white matter (WM) in the periventricular zone and in the centrum semiovale.Objective: To track lesion development during disease progression, we compared the spatiotemporal distribution patterns ...
Wilmott James - - 2012
Wilmott J, Haydu L, Bagot M, Zhang Y, Jakrot V, McCarthy S, Lugassy C, Thompson J, Scolyer R & Barnhill R (2012) Histopathology Angiotropism is an independent predictor of microscopic satellites in primary cutaneous melanoma Aims:  To establish whether microscopic angiotropism of melanoma cells correlates with microscopic satellite (MS) formation ...
Lescher Juliane - - 2012
Here we demonstrate that miRNA regulation in marmoset (Callithrix jacchus) and C57/BL6 mouse EAE lesions largely resembles miRNA regulation in active human MS lesions. Detailed quantitative PCR analyses of the most up- and downregulated miRNAs of active human MS lesions in dissected lesions from marmoset EAE brains and inflamed spinal ...
Altintas A - - 2012
Background: Demyelinating lesions over 20 mm in size, referred to as tumefactive demyelinating lesions, can be misdiagnosed as being either a tumor or an abscess. Although some radiological characteristics can help make a differential diagnosis easier, a cerebral biopsy may still be necessary.Objective: Our objective was to assess the clinical ...
Hagemeier Jesper - - 2012
PURPOSE: To investigate phase lesions identified on susceptibility-weighted imaging (SWI)-filtered phase images in patients with multiple sclerosis (MS), clinically isolated syndrome (CIS) and healthy controls (HC). To relate phase lesion characteristics to other clinical and MRI outcomes. MATERIALS AND METHODS: 95 relapsing-remitting (RR), 40 secondary-progressive (SP) MS patients, as well ...
Karimaghaloo Z - - 2012
Gadolinium-enhancing lesions in brain MRI of Multiple Sclerosis (MS) patients are of great interest since they are markers of disease activity. Identification of gadoliniumenhancing lesions is particularly challenging because the vast majority of enhancing voxels are associated with normal structures, particularly blood vessels. Furthermore, these lesions are typically small and ...
Karlik Stephen J - - 2012
What is the origin of the complex vascular changes that exist in the CNS lesions of Multiple Sclerosis (MS)? From the beginning of the study of the pathological changes in MS in the 19th century, lesions were seen to be associated with veins. On a microscopic level, there have been ...
Hoorbakht Hedieh - - 2012
The aim of this review is to summarize the latest information about optic neuritis, its differential diagnosis and management. Optic Neuritis (ON) is defined as inflammation of the optic nerve, which is mostly idiopathic. However it can be associated with variable causes (demyelinating lesions, autoimmune disorders, infectious and inflammatory conditions). ...
Ali Ibne Karim M - - 2012
The category B agent of bioterrorism, Entamoeba histolytica has a two-stage life cycle: an infective cyst stage, and an invasive trophozoite stage. Due to our inability to effectively induce encystation in vitro, our knowledge about the cyst form remains limited. This also hampers our ability to develop cyst-specific diagnostic tools. ...
Popescu Bogdan F Gh - - 2012
Although historically considered a disease primarily affecting the white matter of the central nervous system, recent pathological and imaging studies have established that cortical demyelination is common in multiple sclerosis and more extensive than previously appreciated. Subpial, intracortical and leukocortical lesions are the three cortical lesion types described in the ...
Kalanie Hossein H Mehr Hospital, Shahid Beheshti University of Medical Sciences, Tehran, - - 2012
Tumefactive demyelinating lesion is defined as large solitary demyelinating lesion with imaging characteristics mimicking neoplasm. These atypical features include size more than 2 cm, mass effect, edema, and/or ring enhancement. Distinguishing tumefactive lesions from other etiologies of intracranial space occupying lesions is essential to avoid inadvertent surgical or toxic chemotherapeutic intervention. ...
Yue Qiang - - 2011
This study was aimed to explore the value of quantitative proton MR spectroscopy (1H-MRS) in the differentiation of benign and malignant meningioma. 23 cases, including 19 benign (grade I) and 4 malignant (grade II-III) meningiomas, underwent single voxel 1H-MRS (TR/TE = 2000 ms/68, 136, 272 ms). T2 relaxation time of ...
Horie C - - 2011
Background: It is well known that varicella zoster virus (VZV) exhibits tropism for the epidermis and follicular epithelium; while little attention has been paid to eccrine gland and duct involvement by VZV. However, the presence of herpetic syringitis in immunocompromised hosts suggested us the possibility of eccrine gland and duct ...
Khreish Fadi - - 2011
The present report demonstrates the usefulness of nuclear medicine in differentiating different pulmonary tumors. A 79-year-old woman presented with a suspicious peripherally located lesion of the right lower lobe in the costophrenic angle. During bronchoscopic evaluation, a centrally located intrabronchial lesion was found, which was positive on a subsequent In-111 ...
Ko Hyang Mi - - 2011
Two cases are described of crystal storing histiocytosis (CSH) associated with extranodal marginal zone lymphoma, presenting as lung and subcutaneous masses respectively. Fine-needle aspiration of subcutis and smears prepared from the resected lung masses showed negative images. Cytology slides of both cases were reviewed to identify cytomorphological features for the ...
Dudeck Oliver - - 2011
The aim of this study was to identify criteria for nodule characterization on chest computed tomography in patients with soft tissue sarcomas. In 195 patients, a total of 194 benign and 117 malignant subcentimeter lung nodules were retrospectively analyzed according to lesion size, shape, margins, density, and localization. Benign lesions ...
Miyazaki Hideki - - 2011
A 52-year-old man received a left pneumonectomy for pulmonary squamous cell carcinoma without signs of recurrence after surgery. At age 68 years, a capsulated huge mass developed in the left pleural cavity, which was diagnosed as chronic expanding hematoma. Two years and 8 months after detection, the lesion began to ...
Ahmed Adel Refaat - - 2011
BACKGROUND: Secondary bone lesions in the affected limb (SLAL) could appear after the limb-saving operation for osteosarcoma. If limb-saving surgery with a reduced surgical margin is contributing to the appearance of SLAL and eventually make the prognosis worse, we should prefer more extensive surgery. On the other hand, if SLAL ...
Roth Kjetil - - 2011
AIM: The aim of the study was to evaluate endobronchial ultrasound (EBUS) for peripheral lung lesions and to find the most cost effective combination of sampling techniques. MATERIALS: 264 patients with lesions suspicious of malignancy were recruited in Bergen and Aalesund, Norway from 2005 to 2008. METHODS: The study was ...
Fatima Nazneen - - 2011
Increasing demand for accurate differentiation of pulmonary squamous cell carcinoma (SQCC) from other subtypes can be challenging for pathologists. This is more so in fine-needle aspirations (FNA) since the sample is small and SQCC may show degenerative changes and necrosis that distort the cellular features. Immunohistochemistry (IHC) is a valuable ...
Chee Alex - - 2011
PURPOSE OF REVIEW: Tunneled pleural catheters (TPCs) have become a popular therapeutic tool for chronic pleural effusions. Although the main indication for a TPC has been recurrent, symptomatic, malignant pleural effusion, there are increasing reports of TPC usage in other medical conditions. This article will address the utility of TPCs ...
Yoon Hye-Jung - - 2011
Malignant pigmented villonodular synovitis (PVNS) is an extremely rare lesion. Approximately 30 cases of malignant PVNS have been reported to date and of these, only 1 case involved the temporomandibular joint. Owing to the rarity of well-documented cases and the heterogeneous histologic features of this group of tumors, there has ...
Mota Patrícia Caetano - - 2011
The authors describe a case of a 47-year-old male smoker with a 3-month history of hearing loss, tinnitus and dizziness. Physical examination revealed neurosensory hearing loss. Small rounded hypodensities without mass effect were evident in a computed tomography scan of the head, confirmed by brain magnetic resonance imaging as multiple ...
Ferretti Gilbert R - - 2011
Detecting potentially malignant changes in a pure ground-glass nodule (GGN) is challenging. The development of a solid component is a known sign, which may help in differentiating benign from malignant GGN. We report the case of a 58-year-old man presenting with a pure GGN in the posterior segment of the ...
Feragalli B - - 2011
The mediastinal lines visible at conventional radiography represent the interfaces between the mediastinum and adjacent lung parenchyma. Preservation, obliteration, thickening and distortion of these lines represent the key to detecting and localising mediastinal abnormalities on chest radiographs. The learning objectives of this review are to: illustrate radiographic anatomy of the ...
Scarlata Francesco - - 2011
Cystic hydatidosis is a zoonosis endemic both to Sicily and other Mediterranean areas. Generally, Echinococcus granulosus tapeworms develop in the liver, lung and less frequently in the peritoneum, spleen or kidney. We present a rare case of spinal hydatid disease. The patient was a 38-year-old housewife with a vertebral echinococcosis ...
Hasano─člu Hatice Canan - - 2011
Fibrosarcoma is a mesenchymal tumor constituted by malignant fibroblasts. Myxofibrosarcoma is one of the fibrosarcoma variants that mostly develops from dermal/subcutaneous tissues. The most common locations are the limbs, with rare occurrences in the chest, head, and neck. Since, to best of our knowledge, there is no such report in ...
Shin Na-Young - - 2011
A diffuse interstitial infiltrative pattern of lung metastasis in a patient with malignant melanoma is rare and can be confused with benign conditions such as pulmonary edema or drug-induced pneumonitis. We experienced a case of diffuse interstitial infiltrative lung metastasis in malignant melanoma in a 37-year-old man. This case was ...
Goo Jin Mo - - 2011
As the detection and characterization of lung nodules are of paramount importance in thoracic radiology, various tools for making a computer-aided diagnosis (CAD) have been developed to improve the diagnostic performance of radiologists in clinical practice. Numerous studies over the years have shown that the CAD system can effectively help ...
Chabot-Naud Andréa - - 2011
A case of azygos lobe is presented. An azygos lobe is an accessory lobe of the lung that may occasionally be confused with a pathological process such as a bulla, lung abscess or neoplasm. Its pathogenesis is discussed, as are the characteristic x-ray features that enable an accurate diagnosis.
Andrade Cristiano Feijó - - 2011
Congenital lung malformations are rare and vary widely in their clinical presentation and severity, depending mostly on the degree of lung involvement and their location in the thoracic cavity. They can manifest at any age and can be the source of significant morbidity and mortality in infants and children. Individuals ...
Zahr Zaki Abou - - 2011
Dermatomyositis is associated with an underlying malignancy in about 24% of cases. This association is also true for polymyositis but is less prominent. The malignancy is usually an adenocarcinoma of the ovary, lung, or gastrointestinal tract in Western countries and nasopharyngeal carcinoma in Southeast Asia, Southern China, and Northern Africa. ...
Goktalay Tugba - - 2011
Persistent hydropneumothorax has been diagnosed in a 62-year-old female with a history of blunt trauma, although she has been treated with chest tube and closed underwater seal drainage. Thorax computerized tomography findings were consistent with "fallen lung" and fiberoptic bronchoscopic (FOB) findings have also supported the diagnosis. A cavitary lesion ...
Klein Justin D - - 2011
Hybrid lesions are part of a spectrum of rare pulmonary diseases that are characterized as having elements of both congenital pulmonary airway malformation and bronchopulmonary sequestration. Fetal thoracic masses arise from alterations during lung development that are separated by timing of the inciting event and are often associated with an ...
Ksienski Doran - - 2011
: Uterine sarcomas account for approximately 3% to 7% of all uterine malignancies. Distinguishing benign and malignant myomas based on physical examination and imaging alone is challenging. : A postmenopausal woman with a history of leiomyomas presented to the Emergency Department with chest pain and a right upper lobe lung ...
Yoshikawa Takeshi - - 2011
We report a case of lung cancer arising from the wall of a giant bulla. A 58-year-old man consulted a physician because of bloody sputum. Chest computed tomography (CT) revealed a left upper giant bulla with partial thickness of the wall. Cytology of both sputum and transbronchial brushing was negative ...
Choudhury M - - 2011
Pleuropulmonary blastoma is a rare childhood neoplasm accounting for less than one percent of all primary malignant lung tumors of children less than six years of age. Metastasis to CNS, orbit and iris, bone, contralateral lung and rarely adrenal glands, liver, kidney and pancreas has been described. This report presents ...
Nayak A - - 2011
A. Nayak, V.K. Iyer and S. Agarwala The cytomorphologic spectrum of Wilms tumour on fine needle aspiration: a single institutional experience of 110 cases Objective:  To analyse the cytomorphologic spectrum of Wilms tumour (WT) on aspirates, the largest series reported to date. Study design:  Adequate aspirates from paediatric renal tumours ...
Pors Susanne E - - 2011
With the aim to extend the present knowledge on possible systemic spreading of Pasteurella multocida in pigs with bronchopneumonia, the occurrence and associated lesions of P. multocida were described by comparing cultural detection, pathological evaluation and in situ hybridization of P. multocida in lungs, hearts and kidneys from cases of ...
Warabi Yoko - - 2011
For the purpose of predicting multiple sclerosis (MS) and neuromyelitis optica (NMO) relapses in Japanese population, we evaluated the localization and age of each demyelinating attack. We retrospectively analyzed the 78 medical records of Japanese MS and NMO patients. Then we identified 49 cases of relapsing-remitting-type patients and defined each ...
Amorim A - - 2011
Bronchiectasis (BE) is characterized by irreversible dilation and damage to the bronchial walls. It is a morphological expression of a large variety of pathologies. The true prevalence of BE is unknown. It is known, however, that in Third World countries it is common due to lung infections. Its current prevalence ...
Karavdic Kenan - - 2011
Hydatide disease is endemic in sheep and cattle-raising areas world wide. Its prevalence is also high in the Mediterranean region including Bosnia and Herzegovina. Retrospective appraisal of the pressentation, approach to surgical treatment and outcome of hydatid disease in children at the Clinic for Pediatric Surgery and Clinic for Thoracic ...
Tachikawa Ryo - - 2011
We herein present an autopsy case of occult lung adenocarcinoma that masqueraded as rapid progression of preexisting asbestosis. A 66-year-old man with an initial diagnosis of asbestosis experienced progressive dyspnea for over four years, and eventually died of respiratory failure. A series of chest computed tomography scans showed progression of ...
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