Search Results
Results 201 - 250 of 1706
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Quintin Emilie - - 2010
The present study objective was to evaluate the incidence of methotrexate (MTX)-specific liver lesions from the analysis of a liver biopsy of inflammatory arthritis patients with elevated liver enzymes. A case-control study was performed with 1,571 arthritis patients on long-term low-dose MTX therapy. Results of liver biopsy were analyzed in ...
Al-Jabri Talal - - 2010
Inflammatory myofibroblastic pseudotumours of the liver are rare tumour-like lesions that can mimic malignant liver neoplasms. The symptoms and radiological findings of this rare tumour can pose diagnostic difficulties. We describe a 69-year-old gentleman who was admitted to our department with symptoms suggestive of acute cholecystitis. Ultrasonography and computed tomography ...
Cho Seung Hyun - - 2010
This study was designed to investigate the potential usefulness of acoustic radiation force impulse (ARFI) elastography to evaluate focal solid hepatic lesions. In total, 51 patients with 60 focal hepatic lesions, which included 17 hemangiomas, 25 hepatocellular carcinomas (HCCs), 15 metastases and three cholangiocarcinomas, underwent ARFI elastography. The lesions were ...
Koike Naoto - - 2009
AIM: To evaluate the utility of diffusion-weighted imaging (DWI) in screening and differential diagnosis of benign and malignant focal hepatic lesions. METHODS: Magnetic resonance imaging (MRI) examinations were performed using the Signa Excite Xl Twin Speed 1.5T system (GE Healthcare, Milwaukee, WI, USA). Seventy patients who had undergone MRI of ...
Reall G - - 2009
AIM: To investigate the volume and provision of local liver histopathology in the 11 hospitals of the Yorkshire region outside Leeds, as a potential model for a hepatopathology network. METHODS: Postal questionnaire to all histopathologists in 11 hospital trusts in Yorkshire. RESULTS: Liver biopsies represent about 0.5% histopathology requests in ...
Ganesan K - - 2009
Capsular retraction is an infrequent but characteristic feature of malignant liver lesions such as hepatic metastases and intrahepatic cholangiocarcinoma. Rarely, this finding may be observed in association with benign lesions, such as atypical haemangiomas. Capsular retraction has not previously been reported in association with hepatic inflammatory pseudotumour (IPT). Hepatic IPT ...
Lata Jan - - 2009
This report presents a survey of current knowledge concerning one of the relatively frequent and severe complications of liver cirrhosis and associated ascites-spontaneous bacterial peritonitis. Epidemiology, aetiology, pathogenesis, clinical manifestation, diagnosis and present possibilities of treatment are discussed.
Lee Way Seah - - 2009
AIM: To ascertain the usefulness of a histological scoring system devised to assist in the interpretation of liver histology in neonatal cholestasis (NC). METHODS: Liver biopsy specimens obtained from infants with NC referred to a tertiary pediatric unit in Malaysia were prospectively studied. The first author, blinded to the final ...
Herath Nirmitha I - - 2009
There is significant regional variation in the etiologic agents responsible for hepatocellular carcinoma (HCC), which influences the genetic and epigenetic mechanisms of malignant transformation. The aim of the present study was to investigate the prevalence of allelic imbalance (AI) and CpG island methylation in HCCs from Australia and South Africa. ...
Braun Ueli - - 2009
Ultrasonography is a valuable tool for the diagnosis of liver disease. Discrete or diffuse lesions can be imaged, aspirated, and biopsied under visual guidance. The ultrasonographic examination of the liver is performed on the right side of the standing animal using a real-time 3.5 to 5.0 MHz linear or convex ...
Santoro Lucia - - 2009
To improve characterization of focal liver lesions by a prospective quantitative analysis of percentage signal intensity change, in dynamic and late phases after slow (0.5 mL/s) Resovist administration. Seventy-three patients were submitted on clinical indication to MR examination with Resovist. Signal intensity of 92 detected focal lesions (5-80 mm) were ...
Tokunaga Yukihiko - - 2009
BACKGROUNDS/AIMS: Laparoscopic hepatectomy may provid a less invasive treatment and diagnostic modality. To date, however, few reports have been published on a clinical usefulness of laproscopic hepatectomy using vessel sealer (VS) and soft-coagulation system (SC) for small hepatic tumors suspected of malignancy. METHODOLOGY: Case 1; A 58-year-old man presented with ...
Culafić Djordje M - - 2009
BACKGROUND: The liver actinomycosis is a rare disease associated with complex differentiation from the liver metastases or hepatocellular carcinoma. CASE REPORT: A 50-year-old immunocompetent female patient was admitted to the Surgical Department in an exhausted condition, with dyspnea, significant weight loss and intermittent fever in the recent two months. Diagnostic ...
Cresswell Adrian B - - 2009
Despite a growing body of evidence reporting the deleterious mechanical and oncological complications of biopsy of hepatic malignancy, a small but significant number of patients undergo the procedure prior to specialist surgical referral. Biopsy has been shown to result in poorer longterm survival following resection and advances in modern imaging ...
Liu Yuan-Jian - - 2009
AIM: To investigate and evaluate the pathological features and diagnostic value of focal nodular hyperplasia (FNH) with multi-section spiral computed tomography (MSCT) and postprocessing. METHODS: A total of 25 patients with FNH who had undergone MSCT and postprocessing were included in the investigation. All patients had been pathologically or clinically ...
Kleiner David E - - 2009
The liver biopsy is frequently used as an adjunct diagnostic test in the evaluation of drug-induced liver injury (DILI). A biopsy may be performed to confirm the diagnosis, especially when there is a complex clinical differential diagnosis that includes DILI. A biopsy can also be used to stage the severity ...
Luca Angelo - - 2010
To define the prevalence of different multidetector-row computed tomography (MDCT) vascular patterns and their histopathological correlation with liver explants, and to evaluate the accuracy of MDCT for the diagnosis of hepatocellular carcinoma (HCC). We retrospectively reviewed 125 cirrhotic patients imaged by MDCT before liver transplantation. Three main vascular patterns were ...
Kamaya Aya - - 2009
Hypervascular hepatocellular lesions include both benign and malignant etiologies. In the benign category, focal nodular hyperplasia and adenoma are typically hypervascular. In addition, some regenerative nodules in cirrhosis may be hypervascular. Malignant hypervascular primary hepatocellular lesions include hepatocellular carcinoma, fibrolamellar carcinoma, and peripheral cholangiocarcinoma. Vascular liver lesions often appear hypervascular ...
Lashkari Harsha P - - 2009
Undifferentiated embryonal sarcoma is the uncommon malignant mesenchymal tumor of the liver seen in children and young adults. Radiologic findings reflect the solid to cystic appearances observed in the gross specimens. The discrepancy in the appearances of the mass between the ultrasound scan and computed tomography scan is the hall ...
Capan Mesküre - - 2009
Albendazole therapy--alone or in combination with surgery--remains the standard of care for human echinococcosis depending on the stage of disease. However, only limited data are available on target site concentrations in liver cysts and data for non-liver cysts are lacking. We report on intra-cystic concentrations of the biologically active metabolite ...
Mortelé Koenraad J - - 2009
Cystic lesions of the liver are frequently encountered in clinical practice. In general, they can be classified as developmental, neoplastic, infectious, inflammatory, or miscellaneous lesions. Most cystic focal liver lesions have specific sonographic, computed tomographic, and magnetic resonance imaging features. These features help narrow, in combination with critical clinical information, ...
Feuerlein Sebastian - - 2009
OBJECTIVE: As diffusion-weighted imaging is increasingly implemented into routine protocols of abdominal MRI, abnormal findings in expected and unexpected locations become more common. The aim of our retrospective study was to investigate the specificity of restricted diffusion in differentiation of benign from malignant abdominal disease. MATERIALS AND METHODS: Two hundred ...
Feldstein Ariel E - - 2009
Liver biopsy remains the gold standard for diagnosing nonalcoholic steatohepatitis (NASH). We have recently demonstrated that plasma cytokeratin 18 (CK-18) fragment levels correlate with the magnitude of hepatocyte apoptosis and independently predict the presence of NASH. The goal of this study was to validate the use of this biomarker for ...
Dumortier Jérôme - - 2009
OBJECTIVE: To report a case of acute hepatitis related to atenolol administration in a liver transplant (LT) recipient. CASE SUMMARY: A 57-year-old woman was evaluated for LT because of liver failure due to cirrhosis of unknown origin. LT was performed in November 2006. In March 2007, results of liver function ...
Cugat Esteve - - 2010
BACKGROUND: To present the data of laparoscopy in liver surgery and to assess the real indications and outcomes of this kind of approach. METHODS: From February 2000 to March 2008, a prospective study was performed on 182 patients from 15 Spanish surgical centres. RESULTS: A total of 308 lesions was ...
Boursier J??r??me - - 2009
BACKGROUND AND AIMS: Blood tests and liver stiffness evaluation (LSE) by ultrasonographic elastometry are accurate tools for diagnosing liver fibrosis. We evaluated whether their synchronous combination in new scores could improve the diagnostic accuracy and reduce liver biopsy requirement in algorithm. METHODS: Three hundred and ninety patients with chronic liver ...
Nassar A - - 2009
Glypican-3 (GPC-3), a membrane-anchored heparin sulfate proteoglycan, has been shown to be expressed in approximately 80% of hepatocellular carcinoma (HCC) but not in benign hepatic lesions. Survivin, a novel inhibitor of apoptosis, and a prognostic marker, has also been expressed in HCC. We evaluated these two immunomarkers (GPC-3 and survivin) ...
Guillot Martin - - 2009
While abdominal ultrasound and ultrasound-guided fine-needle aspiration cytology are often combined to help determine the type of liver disease in dogs, little is known about the relationship that may exist between the results of these tests. We hypothesized that specific sonographic findings, or combinations of findings, may predict results of ...
López-Andújar Rafael - - 2009
The caudate lobe can be the origin of primary liver tumours or the sole site of liver metastases. This lobe is anatomically divided into 3 parts: Spiegel's lobe (Couinaud's segment 1), paracaval portion (Couinaud's segment 9), and the caudate process. In this series of 4 cases, we provide a step-by-step ...
Salguero F J - - 2010
A mass was identified within the left lateral lobe of the liver of a 10-year-old Eurasian badger (Meles meles). The mass was friable and multilobulated, with blood-filled spaces between the lobules. Microscopically, the lesion consisted of sheets and trabeculae of neoplastic hepatocytes often forming cystic spaces containing erythrocytes, fibrin and ...
Strobel D - - 2009
AIM: To evaluate the incidence and diagnostic accuracy of tumor-specific vascularization pattern in contrast-enhanced ultrasound (CEUS) in the differential diagnosis of liver tumors in clinical practice. MATERIALS AND METHODS: From May 2004 to December 2006 1349 patients (male 677, female 672) with a hepatic tumor lacking a definite diagnosis based ...
Ratziu Vlad - - 2009
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. The main cause of NAFLD is insulin resistance; therefore, it is necessary to assess liver injury in patients with overweight and insulin resistance-related complications. The two main forms of primary NAFLD, steatosis and steatohepatitis (NASH), most likely ...
Onodera Manabu - - 2009
Liesegang rings (LR) are acellular, laminated structures that may be deposited within and around cysts and inflamed or necrotic tissue. Previous reports have shown that the kidney and breast are commonly affected organs of LR. Herein is reported a rare case of biliary deposition of LR presenting as a tumor-like ...
Drebber Uta - - 2009
The purpose of the present study was to characterize histopathological lesions in primary biliary cirrhosis (PBC) and to assess the relationship between histopathological lesions and biochemistry. Liver biopsies of 252 patients with PBC were investigated. A laboratory database was established. Histopathological characterization was performed. Relationships between detailed histopathological features and ...
Masood A - - 2009
Primary non-Hodgkin lymphoma (NHL) of liver is a very rare malignancy. Here, we report the case of a 65-year-old man who presented with constipation and right groin pain of 2 months' duration. A computed tomography (CT) scan of the abdomen incidentally detected multiple hypodense nodules in both lobes of the ...
Assy Nimer - - 2009
Due to the widespread clinical use of imaging modalities such as ultrasonography, computed tomography and magnetic resonance imaging (MRI), previously unsuspected liver masses are increasingly being found in asymptomatic patients. This review discusses the various characteristics of the most common solid liver lesions and recommends a practical approach for diagnostic ...
Futei Y - - 2009
Hypergammaglobulinaemic purpura (HP) is commonly found in Sjögren's syndrome. We report a rare association of HP arising in a patient with alcoholic liver cirrhosis. A 65-year-old man presented with palpable purpura on the legs. Histological examination of a biopsy taken from the purpura found leucocytoclastic vasculitis in the superficial and ...
Del Poggio P - - 2009
We describe the case of a 77-year-old woman with chronic hepatitis C and well compensated cirrhosis in whom a single encapsulated 5.5 cm hepatocellular carcinoma was found in the right liver lobe. The patient was symptomatic with left upper quadrant pain and had elevated alfa-fetoprotein levels (3133 ng/ml). While she ...
Leelawat Kawin - - 2009
Hepatolithiasis is well known to represent an etiology of cholangiocarcinoma. The average age of patients with a diagnosis of cholangiocarcinoma that occurs as a complication of hepatolithiasis is about 62-year-old. Here, the authors present a case of cholangiocarcinoma that occurred in a 24-year-old woman who presented with the recurrent cholangitis ...
Wang Yongxin - - 2009
The purpose of this article is to report a case of unilocular primary spinal extradural hydatid cyst which manifested as acute bleeding. The clinical presentation, diagnosis, and surgical treatment of this rare case are discussed and published cases of primary extradural hydatid cysts are reviewed. Complete recovery was achieved. Repeated ...
Ong Seok Ling - - 2009
This article reviews the therapeutic efficacy and complications of microwave ablation (MWA) in the treatment of primary and secondary liver malignancies. A PubMed search using keywords 'microwave', 'liver', 'malignancy', 'cancer' and 'tumour' was performed to identify articles related to MWA of liver malignancies published in English from 1975 to February ...
Braun U - - 2009
This case report describes the clinical, ultrasonographic and postmortem findings in an alpaca with Mycobacterium kansasii infection. The alpaca was referred because of chronic weight loss and weakness. The results of clinical examination, haematology and serum biochemistry were not diagnostic. Ultrasonography of the liver revealed multiple, hyperechogenic lesions with a ...
Karaman Musa - - 2009
Histomoniasis was detected and described in naturally affected 35 turkeys. A polymerase chain reaction, which amplified a 209 bp region from the small subunit ribosomal RNA gene of H. meleagridis, was used and compared to the detection by histopathological observation of the histomonad trophozoits. In gross examination, typical histomoniasis lesions ...
França M - - 2009
A deceased 10-yr-old male ostrich was diagnosed with severe necrotizing enteritis and septicemia. The bird was inappetent for 3 wk and had neurologic signs 2 days prior to death. Macroscopically, no significant lesions were noted aside from congestion of the liver, kidneys, and spleen. Histopathology revealed severe fibrinonecrotic enteritis,associated with ...
Caruso Settimo - - 2009
Hemangiopericytoma (HP) is an uncommon vascular tumor that rarely develops in the liver. We present the case of a 68-year-old female with a primary HP involving the right lobe of the liver, detected during an abdominal screening sonography. The lesion was further evaluated using multidetector CT. The patient was treated ...
Sentíes-Cué Gabriel - - 2009
An outbreak of systemic histomoniasis in 9-to-11-wk-old meat-type male turkeys associated with high mortality is reported. Clinical signs in turkeys included anorexia, depression, diarrhea, loss of weight, and increased mortality between 7 and 13 wk of age. Seven-week cumulative mortality in the turkeys of affected houses ranged from 24% in ...
Meyns E - - 2009
Gas gangrene of the liver is a rare clinical syndrome associated with a high rate of mortality. It is mostly associated with malignancy and immunosuppression. We report on a male patient who presented at the department of emergency medicine with high fever but no localised complaints. CT scan revealed a ...
Bisceglia Michele - - 2009
In 1999, Nguyen et al divided focal nodular hyperplasia (FNH) in 2 groups, the classical and nonclassical. The former also included those cases of FNH with classical characteristics exhibited "on a subtle scale," whereas the latter included among others mainly the telangiectatic FNH (T-FNH) variant. Hepatocellular adenoma (HCA) was classically ...
Rothuizen Jan - - 2009
A liver biopsy is required to make the diagnosis of most non-vascular liver diseases. Liver biopsy samples can be obtained with several techniques. With proper training and adequate operator experience, the liver biopsy is a safe technique. It is important to evaluate blood coagulation and to use the biopsy in ...
Masyuk Tatyana T Miles and Shirley Fiterman Center for Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, - - 2009
The present review summarizes recent knowledge on polycystic liver diseases (PCLDs), mechanisms of hepatic cystogenesis and potential therapies for these conditions. PCLD may be classified as cholangiociliopathies. In PCLD associated with polycystic kidney disease, cell proliferation is one of the major mechanisms of cystogenesis, whereas in isolated PCLD (autosomal dominant ...
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