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Wickramaratne Dayan D Department of Bioengineering, University of California, Los Angeles, CA, USA; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, - - 2014
Diseased tissues exhibit changes in mechanical properties and thus possess clinical diagnostic significance. We report the design and development of a Fine Needle Elastography (FNE) prototype device integrated with Fine Needle Aspiration Cytology (FNAC) needle that allows for quantitative and sensitive assessment of tissues and materials based on local variations ...
Bertens Loes C M LC Julius Center for Health Sciences and Primary Care, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. Electronic address: - - 2014
To assess differences between three different decision-making approaches in the method of panel diagnosis as reference standard in diagnostic research. Within a diagnostic study, the prevalence of heart failure (HF) and chronic obstructive pulmonary disease (COPD) was compared using three approaches of decision making in panel diagnosis. These were (1) ...
Heylen Dieter D Evolutionary Ecology Group, Department of Biology, University of Antwerp, Belgium. Electronic address: - - 2014
The three most common Ixodes spp. ticks found on songbirds in Western Europe are Ixodes frontalis, I. arboricola and I. ricinus. As the latter species is a generalist, it shares several avian hosts with the two strictly ornithophilic species. Infestations of the three species can overlap in time and space, ...
Nizon Mathilde M Reference Center of Inherited Metabolic Diseases, University Paris Descartes, Hospital Necker Enfants Malades, APHP, Paris, - - 2014
Lipoic acid metabolism defects are new metabolic disorders that cause neurological, cardiomuscular or pulmonary impairment. We report on a patient that presented with progressive neurological regression suggestive of an energetic disease, involving leukoencephalopathy with cysts. Elevated levels of glycine in plasma, urine and CSF associated with intermittent increases of lactate ...
Kabekkodu Shama Prasada - - 2013
This study was undertaken to investigate the mitochondrial DNA (mtDNA) variation in non-malignant and malignant cervical tissue samples. We have identified 229 and 739 variations non-malignant and malignant tissues respectively distributed over 321 locations in the D-loop (50 in non-malignant and 166 in malignant; 216 variations), coding region (139 in ...
Perez-Atayde Antonio R - - 2013
A 14-year-old boy with mitochondrial neurogastrointestinal encephalopathy (MNGIE) disease had a lifelong history of failure to thrive and gastrointestinal symptoms including vomiting, pain, and diarrhea, leading to progressive cachexia. At the age of 9 years, after an extensive workup, the diagnosis of Crohn disease was strongly suspected, and he underwent ...
De Cunto A A Department of Neonatology, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, - - 2013
Aspiration of uncontaminated amniotic fluid as a cause of neonatal respiratory distress is scarcely documented. A term neonate who presented with early onset respiratory distress with a radiographic appearance of an aspiration syndrome is therefore reported. Differential diagnosis and implication of this diagnosis in the management of neonatal respiratory distress ...
Cheng Beibei B Department of Electrical and Computer Engineering, Missouri University of Science and Technology, Rolla, MO 65409, - - 2013
Basal cell carcinoma (BCC) is the most commonly diagnosed cancer in the USA. In this research, we examine four different feature categories used for diagnostic decisions, including patient personal profile (patient age, gender, etc.), general exam (lesion size and location), common dermoscopic (blue-gray ovoids, leaf-structure dirt trails, etc.), and specific ...
Carlsson Stefan - - 2012
Abstract Objective. This study aimed to survey current Swedish practices for performing and handling transrectal ultrasound-guided prostate biopsies. Material and methods. A Swedish Urology Network (SUNe) was organized for the distribution of information, survey studies and research collaborations. A web-based questionnaire was distributed to the members in 2011. Results. In ...
Seidenari Stefania - - 2012
Background: Melanomas in situ (MIS) are difficult to diagnose, lacking well-established dermoscopic descriptors. Objective: The aim of this study was to improve the identification of early melanomas describing the variegated dermoscopic features of MIS and their correlation with demographic and clinical aspects. Methods: Dermoscopic images of 114 histologically proven MIS ...
Seidenari Stefania - - 2012
To define the dermoscopic aspects of the network in melanoma in situ (MIS), using both standard and newly introduced network descriptors. Fifty-four histologically confirmed MIS with a reticular pattern, 108 atypical reticular naevi and 108 typical reticular naevi were evaluated for the presence of 11 network descriptors. The ABCD-score and ...
Pant Nitin - - 2012
This report describes an 18-month-old boy with a completely isolated duplication cyst (CIDC) of the ileum associated with another classic enteric duplication cyst in the adjacent bowel and presenting as an acute abdomen due to torsion of the pedicle of the CIDC. Cysts excision was curative.
Lehmann Maryann M Oral & Maxillofacial Pathology, Radiology and Medicine, College of Dentistry, New York University, New York City, NY 10010, - - 2012
Members of the practice-based research network Practitioners Engaged in Applied Research and Learning (PEARL) Network investigated the dentin caries activity in early occlusal lesions and its relationship to patient age, preoperative tooth sensitivity and radiographic appearance, as well as its influence on preparation depth and volume. PEARL Network practitioner-investigators (P-Is) ...
Kim Jong Yeob - - 2012
The distinction of a spitz nevus from a melanoma can be difficult and in some cases, impossible. A misdiagnosed spitz nevus can metastasize and lead to fatal outcomes, especially in children. A 5-yr-old girl presented with a 1-yr history of a solitary pinkish nodule on her left hand. On physical ...
Pralong P - - 2012
Background Lentigo maligna melanoma (LMM) is the most common subtype of melanoma on face. Presentation may be quite subtle particularly in early stages and delayed diagnosis is common. Few dermoscopic studies have been done and the main dermoscopic features of LMM have been defined by W. Stolz and co-workers in ...
Terushkin V - - 2012
Background:  Melanomas vary in growth rate from rapidly developing nodular melanomas to slow-growing melanomas (SGM) that hardly change over years. Objectives:  To evaluate longitudinal changes in dermoscopic findings of SGM. Methods:  We retrospectively analyzed a dermoscopic image dataset, from 15 pigmented lesion clinics, of SGM that were followed sequentially by ...
Varlatzidou Alexandra A Department of Surgery, Attikon University Hospital, University of Athens Medical School, Athens, - - 2011
To investigate capability of combination of learning vector quantizer (LVQ) neural networks (NNs) in discrimination of benign from malignant thyroid lesions. The study included 335 liquid-based cytology, fine needle aspiration (FNA), Papanicolaou-stained specimens. All cases were compared to the histologic diagnosis. Features describing size, shape, and texture of -100 nuclei ...
Gupta Rakesh K - - 2011
Diffusion tensor imaging (DTI) was performed on 25 patients with neurocysticercosis (NCC). The aim of this study was to investigate the changes in DTI measures during the evolutionary course of NCC lesions from vesicular to calcified stage in the brain. DTI measures were quantified from the NCC lesions of all ...
Jang Ki Don - - 2011
We report a case of laparoendoscopic single-site surgery (LESS) for a symptomatic left seminal vesicular cyst and ipsilateral renal agenesis. A 49-year-old man presented with a 1-year history of severe irritation upon voiding and intractable, recurrent hematospermia. A computed tomography scan showed a 68×41×38 mm sized left seminal vesicular cyst ...
Ulla Jose Luis - - 2011
To determine the variety of chemotherapy drugs administrable for malignant pancreatic neoplasm as a result of typification with endoscopic ultrasonography-fine needle aspiration (EUS-FNA). A retrospective assessment, in one center, over a period of 1 year. Only malignant pancreatic neoplasm diagnosed by EUS-FNA was recorded. Benign (serous cystic neoplasm) and potentially ...
Patzer T - - 2011
PURPOSE: The aim of the study was to evaluate the stabilizing function of the long head of biceps tendon (LHB) and its tension, both without and with the presence of SLAP lesion to analyze a potentially occurring humeral chondral print of LHB with consecutive glenohumeral chondral lesions in SLAP lesions. ...
Hahn Soo Yeon - - 2011
The recent American Thyroid Association management guidelines suggest cervical ultrasonography (US) surveillance in patients with differentiated thyroid cancer (DTC). This study was conducted to identify predictive factors that can determine whether subsequent fine needle aspiration guided by ultrasound (US-FNA) is indicated in patients with lesions detected by US after surgery ...
Rogart Jason N - - 2011
Pancreatic cysts are common, however, their diagnosis and classification remains a challenge despite advances in cross-sectional imaging and endoscopic ultrasound with fine needle aspiration (EUS-FNA). To determine the incremental yield of cytologic examination of material obtained from targeted fine needle aspiration ("puncture") of the cyst wall after aspiration of fluid ...
Park Kyung Tae - - 2011
Thyroid fine-needle aspiration (FNA) is used as a screening test of choice for evaluation of thyroid nodules. However, approximately 15% to 25% of the cases are classified as indeterminate, posing dilemmas in decision-making. This study was designed to compare the diagnostic performances of second FNA and core needle biopsy of ...
Kawasaki T - - 2011
T. Kawasaki, S. Nakamura, G. Sakamoto, T. Kondo, H. Tsunoda-Shimizu, Y. Ishii, T. Nakazawa, K. Mochizuki, T. Yamane, M. Inoue, S. Inoue and R. Katoh Neuroendocrine ductal carcinoma in situ of the breast: cytological features in 32 cases Objective:  The purpose of this study was to clarify the cytological features ...
Mayall F - - 2010
Ideally, fine needle aspiration (FNA) cytology should be performed with near-patient assessment of the adequacy of the specimen by a cytopathologist. However, this is often not feasible. A cruder alternative is for the FNA practitioner to examine the gross appearances of the specimen and to try to predict the its ...
Wardeh Rooba - - 2011
Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) has been widely used for the diagnosis of primary and metastatic gastrointestinal (GI) and non-GI malignancies. Few studies have been published to evaluate the accuracy and the cytologic features of EUS-guided paracentesis in the diagnosis and staging of malignant neoplasms. All EUS-guided paracenteses ...
Arnason Thomas - - 2010
Fine-needle aspiration (FNA) biopsy of the parapharyngeal space (PPS) is a diagnostic challenge and sampling is often done without image guidance, often trans-orally. Primary PPS tumors are rare, and there is a broad differential diagnosis. The accuracy of PPS FNA, in particular without CT-guidance and using liquid-based cytology (LBC), has ...
Weber Michelle H - - 2010
The epithelioid variant of myxofibrosarcoma is a rare but recently described entity. We report a case of an elderly woman who presented with a slowly enlarging mass of the right lower extremity. Fine-needle aspiration (FNA) cytology revealed a malignant epithelioid neoplasm. The smears of the aspirate material were highly cellular ...
Vij Mukul - - 2010
Filariasis is a common public health problem in the Indian subcontinent. The diagnosis can be made conventionally by demonstrating microfilaria in peripheral blood smears. Despite it high incidence it is unusual to find microfilariae in fine-needle aspiration (FNA) cytology smears. Microfilariae have been reported in cytological specimens of various organs, ...
Syed Reema - - 2010
Although percutaneous biopsies of the spine at thoracolumbar levels have proven value, the benefit in the sacrococcygeal region has not been presented thoroughly in the literature. This region has unique anatomic and oncologic properties.The cytopathologic files at The Johns Hopkins Hospital over a 20-year-period were searched. Imaging studies and medical ...
Rossi Esther Diana - - 2010
The diagnosis subtyping of lymphoma on specimens collected by endoscopic ultrasound fine-needle aspiration (EUS-FNA) can be extremely difficult. When a cytopathologist is available for the on-site evaluation, the diagnosis may be achieved by applying flow cytometric techniques. We describe our experience with immunocytochemistry (ICC) and molecular biology studies applied on ...
Wu Maoxin - - 2010
Fine-needle aspiration (FNA) is a useful tool for immediate assessment of palpable lesions, especially in the head and neck region. The objective of this study is to evaluate the degree of correlation between Diff-Quik-based onsite diagnosis (OD) and final diagnosis (FD) and further improve the efficiency of FNA practice. Two ...
Bean Sarah M - - 2011
BACKGROUND.: The role of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in the evaluation of spindle cell and mesenchymal lesions is unclear. This study reviews the use of EUS-FNA in diagnosing intrathoracic and intra-abdominal spindle and mesenchymal cell lesions at an academic institution. METHODS.: All EUS-FNA specimens with a significant spindle or ...
Zeppa Pio - - 2011
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an established procedure in lung cancer (LC) staging and in the diagnosis of mediastinal masses. Most of the experiences reported refer to single specialized centers where dedicated teams of endoscopists and pathologists perform the procedure. We report the EUS-FNA experience of a cooperation ...
van Roosmalen Jeroen - - 2010
Fine-needle aspiration (FNA) is the most accurate tool to identify malignancy in solitary thyroid nodules. Although some recommend routinely repeating FNA for nodules that are initially read as benign, there is no consensus. We evaluated clinical relevancy and considered costs of routine follow-up FNA in nodules initially read as benign. ...
Wu Maoxin - - 2011
Our previous study showed that the sensitivity of head and neck fine-needle aspiration (FNA) procedures was significantly better in the cytopathologist-performed group than in the noncytopathologist-performed group (96 versus 67%). Recently, cytopathologists have learned to use ultrasound machines to assist them in performing FNA procedures. This study was designed to ...
Wotruba Angelean L - - 2011
Immediate adequacy assessment for thyroid fine-needle aspirations (FNAs) is standard practice in many cytopathology laboratories. A pathologist is usually present for these time consuming assessments. The purpose of this 5 month study (January 2008-May 2008) was to show that cytotechnologists can accurately provide the majority of immediate adequacy assessments for ...
Koegelenberg Coenraad F N - - 2011
Proximal lung tumors, though not discernable by means of transthoracic ultrasound (US), may cause varying degrees of pulmonary collapse and postobstructive pneumonitis which may give rise to a 'drowned lung' appearance on chest computed tomography (CT) and US. The diagnostic yield for malignancy of US-assisted transthoracic fine-needle aspiration (FNA) of ...
Yang Grace C H - - 2010
This study audits the reliability of ultrasound-guided fine needle aspiration (FNA) in excluding papillary thyroid carcinoma (PTC) in thyroid cysts containing mural nodules, and investigates the histological counterpart of cystic PTC diagnosed on FNA. Using a 10-5 MHz ultrasound probe and a 27-gauge needle, solid portions of thyroid nodules were ...
Sharma Meera - - 2010
Tubercular lymphadenitis (TB-L) is the most common manifestation of extrapulmonary tuberculosis. Excisional biopsy with histopathological examination, Ziehl-Neelsen staining (ZNS) and culture and fine needle aspiration (FNA) cytology, although useful in the diagnosis of TB-L, cannot diagnose a substantial proportion of cases. We investigated the role of an in-house polymerase chain ...
Lin Lien-Fu - - 2010
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was initially introduced for diagnosing gastrointestinal and pancreatic lesions, and later on for lung and mediastinal lesions. It can provide tissue diagnosis of lung cancer where bronchoscopy is non-diagnostic. It is a minimally invasive method for lymph node (N) and metastasis (M) staging of non-small ...
Gouletsou P G - - 2010
Despite its extensive use for evaluation of spermatogenesis and assisted reproduction, the safety and consequences of fine (FNA) and large needle aspiration (LNA) to the testicular parenchyma and its normal function have not been established. This study was performed in order to accurately assess, by serial in vitro ultrasonographic, bacteriologic, ...
Seicean Andrada - - 2010
Endoscopic ultrasonography (EUS) is well suited for assessment of the pancreas due to its high resolution and the proximity of the transducer to the pancreas, avoiding air in the gut. Evaluation of chronic pancreatitis (CP) was an early target for EUS, initially just for diagnosis but later for therapeutic purposes. ...
Turhan Nesrin - - 2011
The objective was to assess EUS-FNA for diagnosing intramural upper GI tract lesions. The subjects were 50 patients (21M/29F) with upper GI submucosal lesions who underwent EUS-FNA at a referral center for GI system over a 12-month period. All cases were followed for 1 year after initial EUS-FNA. Cytologic diagnoses ...
Meijer O L M - - 2010
In the assessment of patients with a clinical suspicion of malignant pancreatic disease, computed tomography (CT) findings are sometimes negative or inconclusive. To determine whether endoscopic ultrasonography (EUS) with or without fine needle aspiration (EUS÷FNA) was conclusive in patients with a clinical suspicion of pancreatic malignancy, in whom CT scan ...
Balachandran Indra - - 2010
Granulosa cell tumors (GCTs) of the ovary are low grade ovarian malignancies with a predilection for late recurrences in the pelvic cavity and occasionally distant metastases. Fine needle aspiration (FNA) can be used to detect such recurrences accurately based on unique cytologic and immunohistochemical features. A 5-cm, retrocaval mass at ...
Hawes Robert H - - 2010
Endoscopic ultrasound (EUS) is one of the fastest growing areas within gastrointestinal endoscopy. Although the growth in the United States has been steady, EUS is exploding in areas of Asia and Eastern Europe. As utilization of EUS is increasing, so is the evolution of the discipline itself. As a result, ...
Prasad Shyam - - 2010
The impact of endoscopic ultrasonography (EUS) on the management of pancreatic cystic lesions remains unclear, and there are no published studies of the Australian experience in this area. The aim of this study was to review the experience of EUS for such lesions within our institution. A retrospective review was ...
Moore Franklin R - - 2010
Fine needle aspiration (FNA) is becoming increasingly important in the diagnosis of salivary gland lesions. One of the diagnostic difficulties that arise from FNAs is the distinction between primary and metastatic tumors. We describe a case where a right cheek/parotid mass was originally diagnosed as acinic cell carcinoma (ACC) upon ...
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