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Staats Paul N PN *Department of Pathology, University of Maryland School of Medicine, Baltimore, MD §James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA †Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland ‡Department of Pathology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, - - 2014
Primary intestinal-type glandular lesions of the vagina are rare. We report a series of 14 lesions, including 1 intestinal-type polyp without neoplastic features, 3 adenomas (2 with high-grade dysplasia), and 10 adenocarcinomas. Patients ranged in age from 20 to 86 years (mean 60 y) and presented with vaginal bleeding or ...
Fruchter Oren O Institute of Pulmonary, Rabin Medical Center, Petah Tiqwa, Israel; The Sackler School of Medicine, Tel-Aviv University, Tel Aviv, - - 2014
The gold standard for the histological diagnosis of interstitial lung diseases (ILD) is an open lung biopsy (OLB). Tissue samples obtained by forceps transbronchial lung biopsies (TBB) are usually too small. We aim to evaluate the efficacy and safety of cryo-TBB for the diagnosis of ILD and to explore its ...
Cornet Edouard E Caen University Hospital, Laboratory of Haematology, Caen, France; University of Caen, Medical School, EA4652, Caen, France; Caen University Hospital, Regional Registry of Malignant Haemopathies of Lower-Normandy, Caen, - - 2014
A large, multicentre, retrospective survey of patients with hairy cell leukaemia (HCL) was conducted in France to determine the frequency of second malignancies and to analyse the long-term effects of the established purine nucleoside analogues (PNAs), cladribine and pentostatin. The survey retrospectively reviewed the medical history of patients and their ...
van Eggermond Anna M AM Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, - - 2014
We assessed risk, localization, and timing of third malignancies in Hodgkin lymphoma (HL) survivors. In a cohort of 3,122 5-year HL survivors, diagnosed before age 51 and treated between 1965-1995, we examined whether risk factors for second and third malignancies differ and whether the occurrence of a second malignancy affects ...
Basaran D D Division of Gynecologic - - 2014
The objective of our study was to evaluate the accuracy of frozen section (FS) in borderline ovarian tumours (BOT) and to define the factors associated with misdiagnosis during FS evaluation. We performed a retrospective review of patients who underwent exploratory laparotomy for an adnexal mass, from January 2007 to July ...
Bizikova Petra P Department of Clinical Sciences and Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, - - 2014
Feline demodicosis due to Demodex cati is a rare skin disease often associated with concurrent disease and generalized immunosuppression. Local immunosuppression due to the application of topical immunomodulatory drugs, such as glucocorticoids and tacrolimus, or by tumour cells has been suggested as a potential trigger for development of localized demodicosis ...
Nair Lawrence L Department of Cardiothoracic Surgery, The Prince Charles Hospital, Brisbane, - - 2014
Bronchogenic cysts arise from an abnormal budding of the ventral diverticulum of the foregut or the tracheobronchial tree, during embryogenesis. Intrapericardial cysts are rare, accounting for 27% of bronchogenic cysts. In this case report, we present a young woman with a symptomatic intrapericardial bronchogenic cyst compressing the superior vena cava. ...
Shields Carol L CL Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, - - 2014
IMPORTANCE The management of symptomatic iris stromal cyst is challenging using methods of aspiration with or without adjunctive cryotherapy, intracameral cautery, or photocoagulation. Failed cases often require surgical resection, with risks for epithelial downgrowth, glaucoma, blindness, and loss of the eye. OBJECTIVE To study the safety and efficacy of the ...
Plaza Jose A JA Division of Dermatopathology, Department of Pathology, Medical College of Wisconsin. Electronic address: - - 2014
Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. We sought to evaluate the clinical and histopathologic features. The clinicopathologic features in patients with localized lymphedema of ...
Carr Carrie M CM Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota - - 2014
Hypertrophic olivary degeneration (HOD) is an uncommon type of transneuronal degeneration. Case reports and case series described in the literature provide a foundation of our current knowledge of HOD. These reports have described HOD most frequently to be unilateral and occurring in association with lesions in the dentato-rubro-olivary pathway. Our ...
Weshahy Ahmed H AH Dermatology Department, Faculty of Medicine , Cairo University, Cairo , Egypt - - 2014
Abstract Background: Cryotherapy has been used in treatment of basal cell carcinoma (BCC). In 1993, Weshahy described his technique for applying cryotherapy in depth, i.e. intralesional cryosurgery (ILC), using Weshahy's cryoneedles. Objective: To assess the clinical efficacy of ILC using Weshahy cryoneedles in the treatment of small- and medium-sized BCC ...
Kamisawa Terumi T Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, - - 2014
Autoimmune pancreatitis (AIP) must be differentiated from pancreatic carcinoma, and immunoglobulin (Ig)G4-related sclerosing cholangitis (SC) from cholangiocarcinoma and primary sclerosing cholangitis (PSC). Pancreatographic findings such as a long narrowing of the main pancreatic duct, lack of upstream dilatation, skipped narrowed lesions, and side branches arising from the narrowed portion suggest ...
De Rossi Scott S SS Department of Oral Health and Diagnostic Sciences, College of Dental Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA; Department of Otolaryngology/Head & Neck Surgery, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA; Department of Dermatology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA. Electronic address: - - 2014
Oral lichen planus (OLP) is commonly found in middle-aged women. Although the cause is unknown, research points to several complex immunologic events and cells that are responsible for the inflammatory destruction and chronicity of these lesions. Biopsy for histologic diagnosis is recommended. The mainstay of treatment remains topical corticosteroids; however, ...
Schneider Erika E 1 All authors: Imaging Institute, Cleveland Clinic Foundation, 9500 Euclid Ave, A-21, Cleveland, OH - - 2014
OBJECTIVE. The purpose of this article is to determine how often a malignant process presents as a lucency near a hip prosthesis, and to classify the frequency and distribution of differential diagnoses of these lytic lesions, and to determine their disposition. MATERIALS AND METHODS. Hip and pelvis imaging examinations obtained ...
Levine Howard H Head and Neck Institute, The Cleveland Clinic, Cleveland, OH, USA. Electronic address: - - 2014
Patients often believe they have a sinus headache when in fact the headache frequently has another cause. The diagnosis of sinus headache can be confusing because of signs and symptoms in common with migraine. Although not as common a diagnosis as migraine, sinus headache and the associated treatments can be ...
Wuerdeman Marc F MF 563d ASB, 159th CAB, 101st Airborne Division, 7973 Strike Boulevard, Fort Campbell, KY - - 2014
Delayed hypersensitivity disorders and food allergies are often challenging for the clinician and patient alike. A recent discovery of an IgE antibody specific to galactose-α-1,3-galactose, which is a carbohydrate abundantly expressed on cells and tissues of beef, pork, and lamb, adds one more tool to aid the clinician in making ...
Yang Justin S JS Department of Orthopedics, Washington University, 660 South Euclid MS 8233, St Louis, MO, - - 2014
Osteochondritis dissecans is a potentially devastating cause of knee pain in adolescents and adults. Prognosis and treatment depends on the stability of the lesion and the age of the patient. Skeletally immature patients with stable lesions are amenable for nonoperative treatment. Nonoperative treatment is less predictable in skeletally mature patients ...
Chattopadhyay Anindya A Consultant Pediatric Surgeon, Department of Pediatric Surgery, Columbia Asia Hospitals, Kolkata, - - 2014
Hypertrophic pyloric stenosis is brought to attention by its characteristic non-bilious vomiting. In a patient with pure esophageal atresia and a feeding gastrostomy, the symptoms were modified and the diagnosis was delayed. This case report highlights the clinical features of this rare combination, whose diagnosis was easily established once the ...
Lindsay Holly H *Fellow in Pediatric Hematology and Oncology †Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine/Texas Children's Hospital, Houston, - - 2014
Pyogenic granulomas (PGs) are benign vascular lesions occurring in skin and mucous membranes, often secondary to trauma or chronic inflammation. Oral PGs have never been described previously in hemophilia. We describe 2 pediatric patients with hemophilia A, who developed PGs with inadequate factor therapy for bleeding. PG pathophysiology suggests an ...
Buppajarntham Aubonphan A Division of Infectious Diseases, Faculty of Medicine, Thammasat University Hospital, Pathumthani, 12120, - - 2014
The diagnosis of gnathostomiasis typically includes a triad of eosinophilia, migratory skin lesions, and exposure risk. The cutaneous manifestations are protean yet often involve intermittent migratory swellings and creeping skin eruptions with abscesses or nodules, which vary in onset and duration. We report the first case of gnathostomiasis presenting as ...
Chen Xu - - 2014
Objective: To establish an expert diagnosis system for cerebrovascular diseases (CVDs) and assess accuracy of the diagnosis system. Methods: An expert diagnosis system for CVDs was established and evaluated using actual clinical cases. Results: An expert diagnosis system for CVDs was established and tested in 319 clinical patients. Diagnosis accordance ...
Middleton Lavinia P LP Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, - - 2014
We evaluated the efficacy of using standard radiologic and histologic criteria to guide the follow-up of patients with lobular carcinoma in situ (LCIS), lobular neoplasia (LN), or atypical lobular hyperplasia (ALH). Patients with high-risk benign lesions diagnosed on biopsy were presented and reviewed in a multidisciplinary clinical management conference from ...
Rogers Erin M EM Division of Pediatric Gynecology, Hospital for Sick Children, University of Toronto,Toronto, ON, Canada. Electronic address: - - 2014
To assess the rate of recurrence of ovarian dermoid cysts in pediatric and adolescent girls at the Hospital for Sick Children. A retrospective chart review of all dermoid cysts surgically managed at the hospital for Sick Children from January 2003 to June 2012. The Hospital for Sick Children, Toronto, Canada. 66 ...
Al-Qahtani Saeed M SM Department of Urology, Tenon University Hospital, Paris, - - 2014
Objective: Our aim was to evaluate the biopsy quality of upper urinary tract urothelial transitional cell carcinoma with a new biopsy forceps (BIGopsy®, Cook Medical) compared to a classic biopsy forceps (Piranha®, Boston Scientific). Patients and Methods: From December 2009 to December 2011, 20 patients with upper urinary tract urothelial ...
Ribeiro Afonso A Division of Gastroenterology and Cytogenetics, University of Miami Sylvester Cancer Center, Miami, - - 2014
Diagnosis of pancreatic malignancy is often based on cytological specimens collected by EUS FNA. Several factors can decrease sensitivity of EUS FNA for pancreatic cancer: well differentiated tumors, pancreatitis, blood, necrosis and slides with low cellularity. The objective of this study is to report on the use of FISH analysis ...
Vassos Nikolaos N Department of Surgery, University Hospital, Erlangen, Germany. Electronic address: - - 2014
Over the past decade, several changes occurred in diagnostics, treatment and understanding of pathogenesis of gastrointestinal stromal tumours (GIST). However, their coexistence with other malignancies of different histogenetic origin remains a challenging issue. Patients diagnosed with GIST in a 10-years period were identified retrospectively and clinical history and findings thoroughly ...
Hodak Emmilia E Department of Dermatology, Rabin Medical Center, Petach Tikva; Sackler Faculty of Medicine, Tel Aviv University. Electronic address: - - 2014
The literature on mycosis fungoides (MF) in children/adolescents is sparse. We sought to evaluate the characteristics of juvenile MF in a large cohort. Data were collected on all patients with MF, aged 18 years or younger at the time of clinicopathologic diagnosis, who attended the Rabin Medical Center Dermatology Department, ...
Ogura Takeshi T Second Department of Internal Medicine, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-shi, Osaka, 569-8686, Japan, - - 2014
No previous studies have compared cytology obtained under endoscopic transpapillary gallbladder drainage (ETGD) and EUS-guided fine needle aspiration (EUS-FNA) for thick-walled gallbladders. The present study investigated the diagnostic yield of bile cytology under ETGD and EUS-FNA for gallbladder tumors. A total of 69 patients were diagnosed as having gallbladder wall ...
Choi Won Seok WS Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of - - 2014
Background: For pulmonary subsolid nodules (SSNs) in patients with extrapulmonary malignancies, it is still unclear what proportion of SSNs is transient and how we can more accurately diagnose these transient SSNs.Purpose: To investigate the frequency of transient SSNs and their differentiating clinical and thin-section computed tomography (CT) features in patients ...
Denzer Ulrike W UW Departments of *Interdisciplinary Endoscopy #Medical Biometry and Epidemiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany †Department of Gastroenterology, Institut Arnault Tzanck, St. Laurent du Var ‡Department of Gastroenterology, Centre Hospitalier Universitaire and University of Nice Sophia Antipolis, Nice, France §Keio University School of Medicine ¶The Jikei University School of Medicine, Tokyo ∥Showa University Northern Yokohama Hospital, Yokohama, - - 2014
Upper gastrointestinal endoscopy is mostly performed under sedation and has a low yield of relevant gastric lesions in patients without alarm symptoms. Simpler screening tests such as capsule endoscopy could be helpful, but gastric visualization is insufficient with the current passive capsules. A magnetically guided gastric capsule was prospectively evaluated ...
Wang Yanqiang Y Department of Neurology, Multiple Sclerosis Center, The Third Affiliated Hospital of Sun Yat-sen University, No 600 Tianhe Road, Guangzhou, 510630, Guangdong, China, - - 2014
Brainstem involvement, especially the medulla oblongata (MO), has been reported in neuromyelitis optica spectrum disorders (NMOSDs). The purpose of this study was to investigate retrospectively and compare clinical, laboratory, and imaging features of NMOSDs with and without MO lesions. A total of 170 patients with NMOSDs were enrolled, including 44 ...
Yin Huabin - - 2014
Study design: This was a retrospective study. The aim of this study was to analyze the clinical characteristics and discuss the treatment options for epidermoid cysts in the lumbar spine.Summary of background data: Epidermoid cysts are rare benign neoplasms, which account for less than 1% of all intraspinal tumors. Due ...
Holmes Brittany J BJ Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, - - 2014
Patients with previously resected papillary thyroid carcinoma (PTC) are monitored for disease recurrence/metastasis by ultrasound surveillance and fine-needle aspiration (FNA) cytology. However, accurate diagnosis in lesions with cystic degeneration may be difficult due to scant cellularity. In the current study, the authors evaluated thyroglobulin in FNA (Tg-FNA) for detecting metastatic ...
Stavros Kara K Department of Neurology, Mount Sinai School of Medicine, New York, - - 2014
Calciphylaxis is a rare condition seen mostly in patients with chronic renal disease and secondary hyperparathyroidism who develop painful skin lesions and myopathy secondary to extensive small vessel calcification, which leads to tissue ischemia. It is typically diagnosed by a biopsy of prominent skin lesions. Here, we report a 49-year-old ...
Wronski Marek M Department of General Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Ulica Banacha 1A, 02-097 Warsaw, Poland. - - 2014
A Sister Mary Joseph nodule represents a cutaneous metastasis into the umbilicus. This clinical sign of intra-abdominal malignancy is frequently overlooked or misinterpreted by both patients and their physicians. We report 4 patients with a Sister Mary Joseph nodule. The umbilical metastases appeared sonographically as hypoechoic masses with irregular margins ...
Branca Giovanni G From the Department of Pathology, University of Messina, Messina, - - 2014
Müllerianosis was first described as a rare entity consisting of an admixture of cervical, tubaric, or endometrial epithelium within the lamina propria and muscularis propria of the urinary bladder. This lesion occurs mainly in the dome or posterior wall of the urinary bladder in women of fertile age. Its clinical ...
Rajabi Mohammad Taher MT Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
to introduce five different type of orbital involvement by hydatid cyst in 8 consecutive patients. descriptive case series. Herein 8 patients with slowly progressive proptosis from 2 to 4months earlier at their first presentation are introduced. Complete ophthalmic examinations were done. Complete blood count, serologic test, ESR (erythrocyte sedimentation rate), ...
Paksoy Mustafa M Dr. Lutfi Kirdar Kartal Education and Research Hospital, Kayısdagı cd. Yamac Apt. No:154 D:12, Göztepe, İstanbul 34731, Turkey. - - 2014
Granular cell tumor (GCT) is an uncommon, primarily benign lesion. We describe 2 cases of GCT. Patient 1 was a 38-year-old man who presented with a reddish, vegetative lesion that involved the posterior third of the left true vocal fold. Patient 2 was an 18-year-old girl who presented with a ...
Ramanan Athimalaipet V AV University of Bristol Hospital Trust, Bristol, United - - 2014
Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory bone disease occurring primarily in children and adolescents. Delays in referral and diagnosis may lead to prolonged courses of antibiotics with in-patient care, substantial radiation exposure from multiple plain radiographs or bone scans and bone biopsies which may be repeated. Children (aged ...
Zhao Juping J Department of Urology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, - - 2014
Adrenal lipomatous tumours (ALTs) are rarely encountered in clinical practice and consequently little is known about their clinical features. We analyze the clinical features, diagnosis and treatment of ALTs based on cases presenting at a single centre over a 31-year period. We reviewed clinical data from patients with primary adrenal ...
Heller Debra S - - 2014
To evaluate cases of endometriosis of the abdominal wall to determine whether the diagnosis was anticipated preoperatively and whether or not the patient had undergone prior surgery. This was a retrospective review of records of patients undergoing surgical resection of abdominal wall endometriosis from 1996-2011. Nine cases were identified. For ...
Lenci Marco Antonio MA Hospital Israelita Albert Einstein, São Paulo, SP, - - 2014
Objective : To evaluate the incidence of premalignant lesions and cancer in endometrial polyps, in patients undergoing hysteroscopic polypectomy. Methods : The results of 1,020 pathological examinations of patients submitted to hysteroscopic polypectomy were analyzed, as well as their diagnostic and surgical hysteroscopy findings. As to their menstrual status, 295 ...
Shaikh Raja R Division of Interventional Radiology, Boston Children's Hospital, Boston, MA, 02115, USA, - - 2014
Glomuvenous malformation (GVM) is an inherited autosomal dominant trait. The lesions, which appear as bluish nodules or plaque-like cutaneous elevations, are usually tender and more firm than sporadic venous malformations. Conventionally, the lesions are thought to be limited to the cutaneous and subcutaneous tissue planes. The objective was to characterize ...
Függer Reinhold R Dept of Surgery, Krankenhaus der Elisabethinen, Fadingerstrasse 1, 4020, Linz, Austria, - - 2014
Diagnosis and clinical work-up of a solid pancreatic mass is a challenging problem. Patients' history, laboratory parameters, computed tomography magnetic resonance imaging, and endosonography are the cornerstones in diagnosis. Biopsy is indicated in selected patients. The main goal of surgical indication is to select patients with suspected malignancy who are ...
Shoji Tadahiro T Department of Obstetrics and Gynecology, Iwate Medical University School of Medicine, Iwate, - - 2014
Forty-one patients diagnosed with atypical glangular cells (AGC) underwent surgery, and the histopathological diagnosis results for the resected specimens and the clinical features were analyzed. Out of 41 patients, final pathological diagnosis was endometrial cancer in 13 patients, cervical adenocarcinoma in 8, AIS in 7, CIN3 in 6, others in ...
Fernandes Juliana Dumêt JD Department of Dermatology, Federal University of Bahia, Salvador, Bahia, - - 2014
Epidermolysis bullosa (EB) nevi are acquired pigmented melanocytic lesions which may have clinical and dermoscopic features quite similar to those found in melanoma. More detailed information on this phenomenon is still lacking. To evaluate clinical, dermoscopic, and histopathological features of melanocytic lesions in 13 patients with dystrophic EB (DEB). Patients ...
Elliott Jessie A JA aDepartment of Surgery, Trinity Centre, St James's Hospital and Trinity College bDepartment of Pathology cDepartment of Immunology dDepartment of Gastroenterology, St James's Hospital, Dublin, - - 2014
Eosinophilic disease of the gastrointestinal tract is rare and is characterized by the presence of gastrointestinal symptoms in association with eosinophilic infiltration of any part of the gastrointestinal tract. Clinical presentation of eosinophilic gastroenteritis (EGE) varies not only by the part of the gastrointestinal tract involved but also with the ...
Martínez-Villén G G Department of Trauma and Orthopaedic Surgery (Hand Surgery and Microsurgery Unit), Miguel Servet University Hospital, 50009 Zaragoza, Spain. Electronic address: - - 2014
Nerve compression syndromes caused by non-neural tumours or tumour-like lesions are rare. We retrospectively reviewed 541 consecutive patients operated on by the same surgeon to study nerve compression syndromes in the forearm and hand. There were 414 due to nerve compression and 127 caused by tumours. Twenty-two patients showed compression ...
Ja Lim Kyoung K Department of Radiology, Hallym University College of Medicine, Kangdong Seong-Sim Hospital, Seoul, Republic of - - 2014
The clinical diagnosis of intussusception remains challenging, because many children with intussusception may present with non-specific signs and symptoms, which overlap with other conditions. Therefore imaging, in particular ultrasonography (US), plays a significant role in the management of these patients. To evaluate how US can contribute to the diagnosis in ...
Jones Rupert C M RC Plymouth University Peninsula School of Medicine and Dentistry, Plymouth, - - 2014
Patterns of health-care use and comorbidities present in patients in the period before diagnosis of chronic obstructive pulmonary disease (COPD) are unknown. We investigated these factors to inform future case-finding strategies. We did a retrospective analysis of a clinical cohort in the UK with data from Jan 1, 1990 to ...
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