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Park Ha Kyoung HK Department of General Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea, - - 2014
We here report on two cases of suspicious cytological findings upon ultrasound (US)-guided fine-needle aspiration (US-FNA) in patients with subacute thyroiditis (SAT). A 46-year-old woman who underwent US-FNA for a suspicious thyroid nodule in the right lobe at a local clinic was referred to our hospital for surgical treatment. Based ...
Yu Dongmei D Department of Special Examinations, Qingdao Women and Children Hospital, Qingdao, China - - 2014
Contrast-enhanced ultrasound (CEUS) is a new noninvasive modality for the diagnosis of thyroid nodules. However, the performance of CEUS in differentiating malignant and benign thyroid nodules has not been systematically evaluated. This meta-analysis was performed to assess the accuracy of CEUS in diagnosing thyroid nodules. PubMed, Embase, and the references ...
Liu Baoxian B Department of Medical Ultrasonics, The First Affiliated Hospital of Sun Yat-Sen University, 58 Zhong Shan Road 2, Guangzhou, 510080, - - 2014
To evaluate the diagnostic performance of two-dimensional shear wave elastography (2D-SWE) in distinguishing malignant from benign thyroid nodules. A total of 331 focal thyroid nodules from 271 patients scheduled for fine-needle aspiration or thyroid surgery were included. After a routine conventional ultrasound evaluation, 2D-SWE examinations were performed to obtain 2D-SWE ...
Pérez-Sayáns M M Oral Medicine, Oral Surgery and Implantology Unit, Faculty of Medicine and Dentistry, Institute of Sanitary Research of Santiago , Entrerrios s/n, Santiago de Compostela C.P. 15782 , - - 2014
The presence and degree of dysplasia are important diagnostic and prognostic criteria for oral leukoplakia, but evaluation of dysplasia is difficult and subjective. Carbonic anhydrase-IX (CA-IX) is expressed primarily in tumor cells and is considered a specific hypoxia marker. We investigated the role of CA-IX in oral leukoplakia. We investigated ...
Kim Baek-Hui BH Korea University Guro Hospital, - - 2014
A 44-year-old man submitted for enlarged thyroid gland. Fine needle aspiration cytology showed bizarre hyperchromatic nuclei and medullary carcinoma was suspected. Thyroidectomy was done and frozen slides revealed hyperplastic thyroid follicles with bizarre nuclei with perithyroidal extension. The frozen diagnosis was malignant neoplasm with extrathyroidal extension. But, permanent sections of ...
Wei Xi X Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin, - - 2014
Background: The meta-analysis was preformed to review the diagnostic accuracy of ultrasound reporting and data system in the diagnosis of thyroid nodules. Methods: We identified the diagnostic accuracy of ultrasound reporting and data system in five databases. Meta-analyses were used in selected studies to obtain pooled sensitivity, specificity, and summary ...
Stokowy Tomasz T Institute of Automatic Control, Silesian University of Technology, ul.Akademicka 16, 44-100 Gliwice, Poland, and; Department of Nuclear Medicine and Endocrine Oncology, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch Wybrzeze AK 15, 44-101 Gliwice, Poland; Department of Clinical Science, University of Bergen, Postboks 7800, NO-5020 Bergen, - - 2014
The inherent diagnostic limitations of thyroid fine needle aspiration (FNA), especially in the "indeterminate" category, can be partially overcome by molecular analyses. We aimed at the identification of miRNAs that could be used to improve the discrimination of indeterminate FNAs. miRNA expression profiling was performed for 17 follicular carcinomas (FTCs) ...
Chen Kuen-Yuan KY Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Department of Surgery, National Taiwan University Hospital, Taipei, - - 2014
To test whether computerized quantification of ultrasonic heterogeneity can be of help in the diagnosis of thyroid malignancy, we evaluated ultrasonic heterogeneity with an objective and quantitative computerized method in a prospective setting. A total of 400 nodules including 271 benign thyroid nodules and 129 malignant thyroid nodules were evaluated. ...
Pozo Eduardo E The Zena and Michael A. Wiener Cardiovascular Institute/Marie-Josee and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine, New York, NY, - - 2014
The noninvasive diagnosis of cardiac amyloidosis (CA) is often challenging. ECG abnormalities are common but lack both sensitivity and specificity. While some features on transthoracic echocardiography have confirmed the classical picture of CA, they have generally been validated against endomyocardial biopsy and thus are indicative of advanced disease. The ability ...
Dinc Bulent B Department of Surgery, Ataturk State Hospital, Antalya, - - 2014
Simple cysts (SCs) of the liver are not associated with the biliary malformations in intrahepatic bile duct biliary. Seen in 0.1% to 7% of adult population, biliary malformations are more common in women. The levels of glycoprotein-like tumor markers (carbohydrate antigen (CA) 19-9) in the cysts and serum could be ...
Agretti P P Department of Clinical and Experimental Medicine, Section of Endocrinology, University of Pisa and University Hospital of Pisa, Via Paradisa 2, 56124, Pisa, - - 2014
Fine-needle aspiration (FNA) with cytologic evaluation is the most reliable tool for malignancy prediction in thyroid nodules, but cytologic diagnosis remains indeterminate for 12-18 % of nodules. BRAF V600E mutation has been reported to show a high specificity for malignant thyroid nodules and the use of this marker to refine indeterminate ...
Spârchez Zeno Z 3rd Medical Department,"O.Fodor" Institute for Gastroenterology and Hepatology,"Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania. - - 2014
Hepatic cysts have a prevalence of 2.5-7% and most of them are asymptomatic. However, large cysts may cause complaints; in such cases an appropriate treatment is necessary (open surgery, laparoscopic deroofing, removal of cystic fluid and injection of a sclerosing agent. The aim of this study was to assess the ...
Gao Bingxia B Department of Gerontology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. - - 2014
The present study aimed to investigate polypoid colonic metastases from gastric stump carcinoma by performing a retrospective analysis of the clinical data of a patient with such a diagnosis, and by discussing other previous case studies from the literature. The patient of the present study was an 80-year-old male who ...
Soma Pier Francesco PF Healthcare Burns Unit, Cannizzaro Hospital, Catania 95126, - - 2014
Primary oral malignant melanoma is a rare condition, accounting for 1.3-1.4% of all melanomas, usually presenting with an aggressive clinical behavior. The present study reports the clinicopathological findings of two cases of oral malignant melanoma and discusses the epidemiology, diagnosis and current therapeutic approaches for this uncommon condition. In the ...
O Wong Ching-Yee CY aDepartment Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine, Royal Oak bCranbrook Educational Community, Bloomfield Hills, Michigan cUniversity of Tennessee, Knoxville, Tennessee, - - 2014
The aim of the study was to evaluate pulmonary nodules (PNs) by incorporating time sensitivity (S) factor in the retention index (RI) and compare with the traditional fixed interval method. After obtaining approval from the Human Investigations Committee, 97 PNs from 81 patients (age=70±11) referred for dual-time fluorine-18 fluorodeoxyglucose PET ...
de Tristan Julie J Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen-Nuremberg Medical School, Waldstrasse 1, 91054, Erlangen, Germany, - - 2014
The objective of the present study is to report on the clinical course and management of thyroglossal duct cysts. Retrospective review of all patients who underwent surgery for thyroglossal duct cysts between 2000 and 2013 at a tertiary referral center was carried out. The operations were performed using a modification ...
Satchi Khami K *Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital; †Department of Anatomical Pathology, St Vincent's Hospital; ‡Centre for Eye Research Australia, Department of Ophthalmology, University of Melbourne; and §Centre for Eye Research Australia, Department of Surgery, University of Melbourne, Melbourne, - - 2014
Melanoma of the conjunctiva may occasionally involve the lacrimal drainage apparatus (LDA). This makes clinical management difficult. The authors describe 5 cases of conjunctival melanoma with LDA disease and make recommendations about its management. Retrospective review of case notes and histopathology reports. Five cases of LDA melanoma arising in patients ...
Val-Bernal Jose-Fernando JF Department of Anatomical Pathology, Marques de Valdecilla University Hospital, Medical Faculty, University of Cantabria and Idival, SANTANDER, - - 2014
Vernix caseosa peritonitis is a rare complication caused by inflammatory response to amniotic fluid spilled into the maternal peritoneal cavity. Most cases occur after cesarean section. We discuss herein two patients, aged 33 and 29 years, who presented with vernix caseosa peritonitis seven to nine days after a cesarean delivery. ...
Noh Tai Kyung TK Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Melasma is triggered by various factors including ultraviolet radiation and estrogen; however, its pathogenesis is unclear. To investigate the inflammatory features of melasma lesions as triggers for this disorder, 197 women with melasma who attended Asan Medical Center and Kangskin Clinic, Seoul, from June 2011 to October 2011 completed a ...
Schwensen Jakob F JF Department of Dermato-Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, 2900, Hellerup, - - 2014
The diagnosis of combined allergic and irritant contact dermatitis is an accepted subdiagnosis for hand dermatitis, and it is often considered in a patient with contact dermatitis, a positive and relevant patch test result, and wet work exposure. We therefore hypothesize that it is arbitrary for wet work exposure to ...
Mehmood Shafqat S Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre Lahore, - - 2014
Endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNA) is considered to be a minimally invasive and safe technique, with low complication rates, for obtaining tissue samples from pancreatic lesions, and mediastinal and intra-abdominal nodes. We retrospectively reviewed the diagnostic accuracy of this method at a tertiary care hospital in Pakistan. The ...
Vanhaecke C C Jr Service de Dermatologie, AP- HP Hôpital Saint Louis, Paris, - - 2014
Keloids are benign fibro-proliferative skin lesions that very rarely occur on the soles. Because of their rarity, the diagnosis of plantar keloids can be difficult. We describe the clinical and histopathological characteristics of eight plantar keloids. All patients presenting with plantar keloids between 2005 and 2012 in our Dermatology unit ...
Radhakrishnan Jayant J Division of Pediatric Surgery, Department of Surgery, University of Illinois, Chicago, IL. Electronic address: - - 2014
Accessory hemi diaphragm (AHD) is an uncommon condition. Its clinical features, diagnosis and management have not been clearly defined. We reviewed the world literature and added a case of our own. There are 40 proven cases in the literature. The lesion occurs almost exclusively in the right hemithorax. Twenty seven ...
Ojha Sandeep S - - 2014
Amyloid goiter is a rare cause of thyroid enlargement which can be confused clinically as well as cytologically with both colloid goiter and neoplastic process of thyroid. A 30-year-old man, diagnosed with chronic kidney disease 5 months previously and currently on dialysis and awaiting renal transplant, was referred by clinicians ...
Karamifar H H Endocrinology and Metabolism Research center, Shiraz University of Medical Sciences, Shiraz,Iran - - - 2014
Skin manifestations, including scalded skin, desquamation, and chronic periorificial dermatitis, are rare clinical signs in the patients with methylmalonic acidemia. This condition may be due to enzyme deficiency or multi--nutrient deficiency because of nutritional restriction. Bullous skin lesion is very rare in these patients and consequently, this type of skin ...
Yasuda Chie C Advanced Technology Research Center, Fancl Research Institute, Totsuka, Yokohama, 244-0813, - - 2014
Different biomarkers are used to evaluate the severity of atopic dermatitis (AD); however, it remains difficult to determine the severity of localized skin lesions. MIF plays an essential role in the pathophysiology of skin inflammation. In order to establish whether the MIF level in the stratum corneum (SC) serves as ...
Ohtsuka Takao T Departments of Surgery and Oncology, Graduate School of Medical Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan, - - 2014
Routine endoscopic retrograde pancreatography (ERP) for pancreatic juice cytology (PJC) during management of intraductal papillary mucinous neoplasm (IPMN) is not recommended in the international consensus guidelines 2012. The aim of the present study was to investigate the roles of PJC in relation to the new stratification of clinical findings in ...
Akbulut Sevtap S Department of Otolaryngology Head and Neck Surgery, Dr. Lutfi Kirdar Kartal Training and Research Hospital, Denizer cd. E-5 Cevizli Mevkii Kartal, Istanbul, Turkey, - - 2014
The aim of this study is to prospectively compare rigid videolaryngostroboscopy with microlaryngoscopy for the diagnosis of benign vocal cord lesions. Eighty-five adult patients with benign vocal cord lesions were evaluated with videolaryngostroboscopy and later underwent microlaryngoscopy. During microlaryngoscopy, systematic examination of the glottis was conducted, including careful inspection and ...
Lee So-Yeon SY Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, - - 2014
The purpose of this study was to investigate whether ultrasound (US) elastography is useful for the early diagnosis of plantar fasciitis. We retrospectively reviewed US elastography findings of 18 feet with a clinical history and physical examination highly suggestive of plantar fasciitis but with normal findings on conventional US imaging ...
Bacci Christian - - 2014
Objective: The dentist has a fundamental role in the early diagnosis of lesions of the oral cavity. The aim of this study was to establish the rate of erroneous clinical diagnoses and whether a clinical diagnosis is enough. The study was conducted to ascertain the overall accuracy of clinical diagnoses ...
Vernooij-van Langen A M M AM Department of Paediatrics, Hospital St Jansdal, P.O. Box 138, 3840 BA Harderwijk, The Netherlands. Electronic address: - - 2014
Early diagnosis through newborn screening (NBS) and early treatment of cystic fibrosis (CF) do lead to better prognosis. In the Netherlands, the median age for a clinical diagnosis is six months, and after newborn screening this is 30days. It is unknown if being diagnosed at the age of six months ...
Gambitta Pietro P Pietro Gambitta, Antonio Armellino, Edoardo Forti, Unità di Chirurgia Endoscopica ed Ecoendoscopia Ospedale Niguarda Ca' Granda, 20162 Milano, - - 2014
To investigate the impact of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in association with a multidisciplinary team evaluation for the detection of gastrointestinal malignancies. A cohort of 1019 patients with suspected malignant lesions adjacent to the gastrointestinal tract received EUS-FNA after a standardized multidisciplinary team evaluation (MTE) and were divided into ...
Kvistad Christopher Elnan CE From the Departments of Neurology (C.E.K., H.O., N.L., L.T., U.W.-A., H.N.) and Radiology (G.M.), Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, Bergen, Norway (C.E.K., L.T.); and Centre of Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway (H.N.). - - 2014
Diffusion-weighted imaging (DWI) is highly accurate in identifying and locating ischemic stroke injury. Few studies using DWI have investigated large subcortical infarctions (LSIs). We aimed to study clinical characteristics, cause, and outcome in patients with ischemic stroke with LSI diagnosed on DWI and compare these with those who had lacunar ...
Treetipsatit Jitsupa J Departments of *Pathology ‡Pediatrics, Stanford University School of Medicine, Stanford, CA †Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, - - 2014
Congenital enteropathies comprise a constellation of rare clinicopathologic diagnoses characterized by intractable watery diarrhea and failure to thrive in infants. These diagnoses include, but are not limited to, tufting enteropathy (TE), microvillous inclusion disease (MID), and enteroendocrine cell dysgenesis (EED). Commonly, the diagnosis is based on identification of their characteristic ...
Ho-Wo-Cheong Dennis D Faculty of Medicine, McGill University, Montreal, QC, - - 2014
To analyze the characteristics and the associated medical co-morbidities in children with synchronous airway lesions (SALs) found during rigid bronchoscopy. Retrospective case series and chart review of patients who were found to have more than one airway lesion after undergoing airway evaluation via rigid endoscopy at a tertiary care pediatric ...
Salvaggio Heather L HL Bassett Healthcare Network, Oneonta, New - - 2014
Hermansky-Pudlak syndrome (HPS) is a rare genodermatosis characterized by oculocutaneous albinism, platelet dysfunction, and in some patients, pulmonary fibrosis and granulomatous colitis. The granulomatous inflammation in the bowel of patients with HPS can be indistinguishable clinically and histologically from that of Crohn disease (CD); however, mucocutaneous granulomatous lesions have not ...
Aung Phyu P PP *Department of Dermatology, Section of Dermatopathology, Boston University School of Medicine, Boston, MA; †Reno Center for Medical Oncology, Winchester, MA; and ‡Dermatopathology Associates, Winchester, - - 2014
: The authors describe a patient with a lesion on the right forearm. Her past medical history was significant for ulcerative colitis (UC, status post-colectomy six months prior). Eleven months earlier, she was diagnosed with myelodysplastic syndrome (MDS), a finding confirmed by bone marrow biopsy showing refractory anemia with excess ...
He Yujun Y Department of General Surgery, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, P.R. - - 2014
Malignant melanoma predominantly occurs in the skin and mucous membranes, thus, malignant melanoma of the breast is particularly rare. In the current study, a case of a 26-year-old female with a malignant melanoma of the breast is presented. On diagnosis of the patient, extensive metastasis had occurred. The patient refused ...
Gutte Rameshwar R Department of Dermatology, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, - - 2014
Palmoplantar lesions in lichen planus (LP) are uncommon. In such cases, diagnosis is usually missed. This study was conducted to document various clinical and histopathological features of palmoplantar LP. A total of 18 patients from our outpatient department with lesions of LP, either predominantly or exclusively on palms and/or soles ...
Reich Adam A Adam Reich, MD, PhD, Department of Dermatology, Venereology, and Allergology Wroclaw Medical University, Ul. Chałubińskiego 1, 50-368 Wrocław, Poland; - - 2014
Neurofibromatosis 1 (NF-1) is an autosomal dominant genodermatosis with an increased risk of developing mesenchymal malignancies. A 28-year-old woman with NF-1 was admitted to our Department for deep ulcers on the right thigh. The ulcerations had appeared about two years earlier, and were initially diagnosed as pyoderma gangrenosum. The patient ...
Kotb Ahmed Fouad AF Department of Urology, Faculty of Medicine, Alexandria University, Alexandria, - - 2014
Microscopic hematuria in men younger than 40 is a confusing issue to urologists, especially when these men have normal radiological findings. We report our experience in looking for urologic malignancy in this group of patients. We conducted a prospective study for men with vague urological symptoms. We included men under ...
C Lavanya L Senior lecturer, Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital , Chennai, India - - 2014
Metastatic carcinomas to the jaw bones are uncommon and comprise to about 1% of all malignant oral neoplasms. It may be the first indication of an unknown malignancy from a distant primary site which is usually associated with poor prognosis. We report a rare case of thyroid carcinoma metastatic to ...
Beyazal Mehmet M Department of Radiology, School of Medicine, Yüzüncü Yıl University, Van, Turkey, - - 2014
The aim of the current study was to assess the efficiency of the apparent diffusion coefficient (ADC) measurement in diagnosis of acute cholecystitis and in differentiation of cholecystitis from extrinsic benign gallbladder wall thickening. Forty patients who were diagnosed to have acute cholecystitis by ultrasonographic examination were included in this ...
Deshmukh Vivek R VR Department of Neurosurgery, Providence Brain and Spine Institute, Portland, Oregon; - - 2014
Object Brainstem cavernous malformations (BSCMs) present a unique therapeutic challenge to neurosurgeons. Resection of BSCMs is typically reserved for lesions that reach pial or ependymal surfaces. The current study investigates the lateral inferior cerebellar peduncle as a corridor to dorsolateral medullary BSCMs. Methods In this retrospective review, the authors present ...
Isidori Andrea M AM From the Departments of Experimental Medicine (A.M.I., C.P., D.G., E.G., A. Lemma, R.P., F.B., F.L., A. Lenzi), Radiologic Science (L.M., V.C.), Surgical Science (G.M.), and Urology (G.F.), Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, - - 2014
Purpose To evaluate the diagnostic accuracy of unenhanced and quantitative contrast-enhanced ultrasonography (US) in the differential diagnosis of small nonpalpable testicular lesions. Materials and Methods The local review board approved the protocol, and all patients provided written informed consent. One hundred fifteen patients (median age, 34 years; age range, 14-61 ...
Jia Wenting W Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, - - 2014
Rhabdoid papillary meningioma is a rare meningioma variant categorized as WHO grade III. We report an 11-year-old girl with an intracerebral rhabdoid papillary meningioma. An 11-year-old girl presented to our hospital with a short history of severe headache and vomiting. MRI revealed a left frontal intracerebral cystic lesion with rim ...
Andrew Nicholas H NH South Australian Institute of Ophthalmology and the University of Adelaide, Adelaide, South Australia, - - 2014
To review the distribution of pathology in lacrimal gland biopsies performed in an Australian cohort. Retrospective review. 268 lacrimal gland biopsies from 263 patients. Pathology archives in South Australia and Victoria were searched for lacrimal gland biopsies performed between 1 January 1997 and 31 December 2012. Data retrieved included the ...
Kargl Simon S Department of Pediatric Surgery, Women's and Children's Hospital, Linz, - - 2014
We try to characterize a previously rather neglected congenital cervical sinus located in the sternoclavicular area in five children. This sinus showed extension to the left sternoclavicular joint in all patients, so we call this congenital lesion "sinus sternoclavicularis." With knowledge of this congenital lesion, diagnosis can easily be established ...
McKechnie Alasdair J AJ United Lincolnshire Hospitals NHS Trust, United Kingdom. Electronic address: - - 2014
See-and-treat surgery has been described as an efficient means of streamlining specialist diagnosis and treatment, and is commonly employed in gynaecology to reduce the delay between cytological screening and definitive treatment of cervical neoplasia. Relatively young patients with predominantly benign skin lesions have been treated in see-and-treat clinics but only ...
Tu Albert A Division of Neurosurgery, University of British Columbia, Vancouver; - - 2014
Perineural cysts are common lesions of the sacral spine. They have rarely been reported in a presacral location, leading to their misdiagnosis as a gynecological lesion. The authors report the second such case, in a patient undergoing fenestration of what was presumed to be a benign pelvic cyst, and the ...
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