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Petric Rok - - 2014
Cytologic examination of a fine-needle aspiration biopsy specimen cannot distinguish between benign and malignant follicular or Hurthle cell neoplasms. Serum thyroglobulin (Tg) concentrations are higher in follicular and Hurthle cell carcinomas than in benign follicular or Hurthle cell tumors, but preoperative measurement of Tg is not recommended for initial evaluation ...
Thipphavong Seng S 1 Joint Department of Medical Imaging, Women's College Hospital, 76 Grenville St, 2nd Fl, Rm 2238, Toronto, ON M5S 1B2, - - 2014
OBJECTIVE. Splenic lesions are commonly encountered and are often incidental in nature. Benign splenic vascular neoplasms include hemangioma, hamartoma, lymphangioma, extra-medullary hematopoiesis (EMH), and sclerosing angiomatoid nodular transformation (SANT). Uncommonly encountered entities of the spleen include focal EMH, focal myeloma, angiomyolipoma, and SANT. Primary splenic angiosarcoma is the most common ...
Perlman Sharon S Antenatal Diagnostic Unit, Department of Obstetrics and Gynecology, The Haim Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, - - 2014
To investigate whether sonographic identification of the fetal anal mucosa (AM) can assist in the diagnosis of anal atresia (AA) in fetuses referred for CAKUT (congenital anomalies of kidney and urinary tract) malformation. During a 3 year study period, 245 fetuses referred for CAKUT were prospectively examined for the presence of ...
Boonyawat Kochawan - - 2014
Hydroxyurea at a relatively low dose is frequently prescribed to induce hemoglobin F production in patients with sickle cell and beta-thalassemia diseases because of its good efficacy and safety profiles. However, a potentially fatal gastrointestinal ulceration was recently found and herein reported. A thirty-seven-year-old man with transfusion dependent hemoglobin E/beta-thalassemia ...
Revzin Margarita V MV Department of Radiology, Yale School of Medicine, 20 York St, New Haven, CT, 06510, USA, - - 2014
This article reviews a spectrum of gallbladder conditions that are either uncommon or represent unusual manifestations of common diseases. These conditions are divided into four major categories: (a) congenital anomalies and normal variants including duplication, ectopia, and lymphangioma; (b) inflammatory processes and stone-related diseases and complications including adenomyomatosis, emphysematous cholecystitis, ...
Ishida Atsuko A *Department of Internal Medicine, Division of Respiratory and Infectious Diseases, St Marianna University School of Medicine, Kawasaki †Department of Pathology, Hiroshima Prefectural Hospital, Hiroshima, - - 2014
A 74-year-old woman with massive bilateral pleural effusion, which was exudative in nature, and with mononuclear cell predominance underwent a pleuroscopy. Parietal pleura were thickened and partly reddish in color. Biopsy specimens taken from the parietal pleura revealed lymphoplasmacytic inflammation with fibrosis. As her performance status rapidly worsened with thoracentesis, ...
Kumar Santosh S Department of Urology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, - - 2014
Hydatid disease is endemic in parts of India, yet genitourinary involvement is rare. Laparoscopic management of such cases is uncommonly reported. We present a case of an adrenal hydatid and its management by laparoscopic aspiration, instillation of scolicidal solution, and partial excision of the cyst.
Kaminska-Winciorek Grazyna G Center for Cancer Prevention and Treatment, Katowice, - - 2014
Acanthosis nigricans (AN) develops sporadically or in association with obesity, insulin-resistance and dark pigmentary phenotype. Unusual clinical presentations of AN may be diagnostically vexing. The aim of the report is to present unusual clinical and dermoscopic pictures of hyper-keratotic, brownish lesions of the nipples resembling acanthosis nigricans. Data including clinical ...
Ostevik L L Faculty of Veterinary Medicine and Biosciences, Department of Basic Sciences and Aquatic Medicine, Norwegian University of Life Sciences, Norway. Electronic address: - - 2014
Two horses with chronic uveitis and histological lesions consistent with equine recurrent uveitis (ERU) were examined. Microscopical findings in the ciliary body included deposits of amyloid lining the non-pigmented epithelium, intracytoplasmic, rod-shaped, eosinophilic inclusions and intraepithelial infiltration of T lymphocytes. Ultrastructural examination of the ciliary body of one horse confirmed ...
Ooi Chin Chin CC Department of Diagnostic Radiology, Singapore General Hospital, Block 2, Level 1, Outram Road, Singapore, - - 2014
We report a case of rare Castleman's disease of the kidney that mimicked a renal neoplasm with emphasis on the imaging and histologic findings. A 47-year-old man presented with dyspeptic symptoms. Ultrasound revealed a vascular, heterogeneous mass in the left kidney. Multiphasic CT scan confirmed an enhancing lesion with enlarged ...
Feely Michael M MM Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, - - 2014
An increased awareness of IgG4-related diseases has led to an escalation in the number of sites known to be involved by this fibroinflammatory disease. We report three cases of IgG4-related cholecystitis which were thought to represent biliary malignancies both clinically and radiographically. All three cases underwent surgery tailored towards presumed ...
Bucci Tommaso - - 2014
Localized amyloidosis in the head and neck is a rare and generally benign condition. In the oral cavity, amyloidosis usually involves the tongue or buccal mucosa. We present the second case of oral amyloidosis arising in the gingiva ever reported, to the best of our knowledge. A 73-year-old White Spanish ...
Liu Guijian G Key Laboratory of Viral Heart Diseases, Ministry of Public Health, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, - - 2014
Asymptomatic cerebral lesions detected by diffusion-weighted magnetic resonance imaging (MRI) following atrial fibrillation (AF) ablation were reported in recent years. It was reported that cardioversion during the procedure of AF ablation was one independent risk factor of asymptomatic cerebral lesions. However, in some studies, the similar association between asymptomatic cerebral ...
Auriel Eitan E From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, - - 2014
To evaluate the local effect of small asymptomatic infarctions detected by diffusion-weighted imaging (DWI) on white matter microstructure using longitudinal structural and diffusion tensor imaging (DTI). Nine acute to subacute DWI lesions were identified in 6 subjects with probable cerebral amyloid angiopathy who had undergone high-resolution MRI both before and ...
Zhang Yuhua Y Department of Ophthalmology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama. Electronic address: - - 2014
To describe the microscopic structure of photoreceptors impacted by subretinal drusenoid deposits, also called pseudodrusen, an extracellular lesion associated with age-related macular degeneration (AMD), using adaptive optics scanning laser ophthalmoscopy (AOSLO). Observational case series. Fifty-three patients with AMD and 10 age-similar subjects in normal retinal health were recruited. All subjects ...
Ha Wn W School of Dentistry, The University of Queensland, Brisbane, - - 2014
The prevalence of oral and maxillofacial pathology has not previously been reported in the Australian paediatric population. This study aimed to audit a large pathology service to provide insight into the prevalence of oral and maxillofacial pathology. Written records of a major Australian oral pathology service were imported into an ...
Haley Erin M EM 1234 E Fletcher St, Philadelphia, PA 19125, USA. - - 2014
We report the case of a 63-year-old woman with a history of undifferentiated connective-tissue disease, polyarthritis, and bilateral carpal tunnel syndrome who presented with generalized pruritus and erythematous and excoriated papules on the trunk and extremities. Empiric scabies treatment was unsuccessful. Patch testing and T-cell receptor gene rearrangement studies were ...
Kaplan Batia B Heller Institue of Medical Research, Sheba Medical Center, Tel Hashomer, - - 2014
Multiple myeloma (MM) and AL amyloidosis (AL) are two malignant forms of monoclonal gammopathies. For the purposes of prognosis and treatment, it is important to distinguish these diseases from the pre-malignant forms of monoclonal gammopathies, such as monoclonal gammopathy of unknown significance (MGUS) and smoldering myeloma (SMM). Routine serum/urine tests ...
Haq Imran I Ocular Oncology Clinic, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, England, - - 2014
Primary involvement of the choroid by extranodal marginal zone lymphoma of MALT type (MALToma) is rare. Here we present a unique case of choroidal MALToma with extensive AL-type amyloid deposition presenting as a diffuse choroidal mass with extra-ocular extension, mimicking uveal melanoma. A-52-year Caucasian male patient was referred to the ...
Jha Abhishek A Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, 202002, - - 2014
Primary hydatid disease of breast is a rare entity and is caused by the larval stage of Echinococcus granulosus. The disease is more commonly seen in sheep-rearing populations and imaging plays a pivotal role in its diagnosis. Several imaging signs have been described in relation to hydatid cysts. However, the ...
Jimenez-Parra Jose David JD Servicio de Urologia y Anatomia Patologica.Hospital Virgen del - - 2014
Amyloidosis is a disease characterised by deposition of eosinophilic hyaline material in different tissues. Urinary bladder involvement is uncommon with less than 200 cases of the primary form published in the literature. We present a new case of primary AA type amyloidosis of the urinary bladder (typical of secondary forms). ...
Constantin V - - 2014
Hidatid cysts of the spleen are a rare occurrence, the spleenbeing the third most common organ for the development ofEchinococcus Granulosus. Splenic hydatid cysts are commonlypart of multi-organ hydatid disease. Diagnosis is oftenestablished when investigating a splenomegaly or by chanceduring an unrelated consult. It can also be diagnosed afterrupture, be ...
di Meo N N Univesity of Trieste, Department of Dermatology and Venereology, Piazza Ospedale I, Trieste, 34129, - - 2014
Primary localized cutaneous amyloidosis is an uncommon lesion (1,2). Recently, Merika EE and coworkers (3) described two patients with localized amyloid lesion of the glans penis and in the literature review they found only 10 previously reported cases. A 50-year-old uncircumcised man presented with an asymptomatic penile lesion, unresponsive to ...
Vrana Julie A JA Mayo - - 2014
Examination of abdominal subcutaneous fat aspirates is a practical, sensitive and specific method for the diagnosis of systemic amyloidosis. In this study, we describe development and implementation of a clinical assay using mass spectrometry-based proteomics to type amyloidosis in subcutaneous fat aspirates. First, we validated the assay comparing amyloid positive ...
Seppi Dario D Multiple Sclerosis Centre of Padova, Department of Neurosciences, University of Padova, via Giustiniani 2, 35128 Padova, - - 2014
The cerebrospinal fluid levels of interleukin-1 beta and structural magnetic resonance parameters of cortical damage, i.e., cortical lesion number and volume, and global cortical thickness, were analysed in multiple sclerosis patients at clinical onset. Cerebrospinal fluid interleukin-1 beta levels strongly correlated with cortical lesion load and cortical thickness, while correlation ...
Chiorean Liliana L Department of Radiology and Computed Tomography, "Octavian Fodor" Institute of Gastroenterology and Hepatology, Cluj-Napoca, - - 2014
Contrast-enhanced ultrasound is widely indicated in the study of splenic diseases, especially due to its good specificity in the differentiation of benign from malignant splenic lesions. The purpose of this pictorial essay is to offer a review of the most common splenic pathologies, while illustrating them with sonographic images.
Nivy Ran R Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, P.O. Box 12, Rehovot 761001, - - 2014
Spirocerca lupi, the dog esophageal worm, typically induces formation of esophageal nodules, which may transform to sarcoma. Ante mortem discrimination between benign and malignant esophageal masses is challenging. Serum acute phase proteins (APPs) are utilized in diagnosis and prognosis of various canine diseases as markers of inflammation. This study characterized ...
Ritchie Simon A SA 59 MDSP/SG07D, 2200 Bergquist Dr, Ste 1, JBSA-Lackland, TX 78236, USA. - - 2014
Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare disorder that manifests as the cutaneous formation of nodules composed of light-chain amyloid. Although the type of amyloid deposit is similar to primary systemic amyloidosis, there seems to be little, if any, crossover between the 2 diseases. Because reports of PLCNA ...
Dehghani Farideh F Department of Dermatology, Shahid Sadooghi University of Medical Sciences, Yazd, Iran. - - 2014
Amyloidosis cutis dyschromica (ACD) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed ...
Tanmahasamut Prasong - - 2014
To determine the prevalence of endometriosis among other benign gynecologic diseases and to identify the characteristics of patients at increased risk of concomitant diagnosis before surgery A descriptive cross-sectional study of331 women with benign gynecologic diseases who underwent surgery in the Department of Obstetrics and Gynecology, Faculty ofMedicine Siriraj Hospital, ...
Sato Kastsumasa K Interventional Cardiology Unit, EMO-GVM Centro Cuore Columbus, Milan, - - 2014
This case report demonstrates a unique strategy requiring a 2.5 mm burr to treat in-stent restenosis of an originally underexpanded stent, implanted in a heavily calcified lesion within a giant aneurysm by Kawasaki disease. Despite our procedural success, it should be emphasized that stent implantation in undilatable lesions should be ...
Créteur Viviane V Erasme Hospital Radiology, Erasme Hospital, 808 Route de Lennik, 1070, Brussels, - - 2014
We describe a case of light chain deposition disease presenting as worsening of renal failure with a lytic femoral bone lesion discovered by sonography. Although sonography cannot be considered to be the test of choice in evaluating multiple myeloma, this technique may allow the detection and the biopsy of osteolytic ...
Tausend William W University of Texas Medical - - 2014
Primary amyloidosis is caused by a monoclonal proliferation of plasma cells and is capable of producing cutaneous lesions. A 56-year-old male was admitted to the hospital for evaluation of chronic back pain and acute lower extremity weakness. On examination, he was noted to have subungual verrucous plaques with overlying nail ...
Emmungil Hakan H Mersin State Hospital, Department of Internal Medicine, Division of Rheumatology, Nusratiye Hometown, Kuvayi Milliye Street No. 32, 33050, - - 2014
Temporal arteritis is most common vasculitis in elderly and imitated by miscellaneous disorders. Temporal artery biopsy is the gold standard test in the diagnosis of giant cell arteritis (GCA). Hereby, we describe a case of a 67-year-old man who presented initially with temporal arteritis; however, a lip biopsy then revealed ...
Mercan Ridvan R Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Gazi University, Ic Hastalıklari ABD, Romatoloji BD, Besevler, 06500 Ankara, - - 2014
Background. Systemic amyloidosis is a potentially fatal condition, unless diagnosed and treated before development of irreversible organ damage. Demonstration of amyloid deposits within tissue biopsies is only definitive diagnostic method, which makes appropriate selection of biopsy site essential. Herein, we evaluated efficacy of minimally invasive minor salivary gland biopsy (MSGB) ...
Al-Dawsari Najla A NA Saudi Aramco Medical Services Organization, Saudi - - 2014
Amyloidosis cutis dyschromia is a rare form of primary cutaneous amyloidosis. Amyloid deposition in the skin occurs without systemic manifestations and produces hypopigmented and hyperpigmented macules. A 19-year-old woman is presented with progression of this condition over 16 years.
Lester Rachael A RA Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota, - - 2014
A 23-year-old woman presented with an 8-month history of asymptomatic thickening of the central areola bilaterally and oily nipple discharge. On examination, there were yellowish-pink papules coalescing into plaques bilaterally. Biopsy showed ectopic sebaceous glands (Montgomery tubercles), known as bilateral areolar sebaceous hyperplasia.
Goodenough Jenny J Department of Plastic & Reconstructive Surgery, Whiston Hospital, Prescot, Merseyside, - - 2014
We report the case of an 84-year-old woman who had a nodal recurrence of melanoma 45 years after the primary diagnosis of an extremity cutaneous melanoma. It is believed to be the longest disease-free latency period reported between primary melanoma diagnosis and recurrence to date. Late recurrences of melanoma are rare ...
Guidry Jacqueline J Baylor College of - - 2014
There is a documented association between diffuse planar xanthoma and chronic myelomonocytic leukemia. Previous accounts have hypothesized that patients with multiple lesions or extensive cutaneous disease are more likely to have an underlying abnormality of the reticuloendothelial system. However, we document a 62-year-old woman with a large pruritic yellow-orange plaque ...
Isrow Derek D Division of Hematology/Oncology, Department of Medicine, Sylvester Comprehensive Cancer Center, Braman Family Breast Cancer Institute Miller School of Medicine in Miami, The University of Miami, Miami, FL, - - 2014
Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy arising in areas rich in apocrine glands, such as the perineum, vulva, axilla, scrotum, and penis. We describe the case of a man in his 50s who initially presented with a small eczematous lesion on his right groin, treated with topical ...
Renard Dimitri D Service de Neurologie, CHU Nîmes, Hôpital Caremeau, Place du Pr Debré, 30029 Nîmes Cedex 4, - - 2014
Background. Thalamic lesions are seen in a multitude of disorders including vascular diseases, metabolic disorders, inflammatory diseases, trauma, tumours, and infections. In some diseases, thalamic involvement is typical and sometimes isolated, while in other diseases thalamic lesions are observed only occasionally (often in the presence of other typical extrathalamic lesions). ...
Son Seung-Myoung SM Department of Pathology, Chungbuk National University College of Medicine, Cheongju, - - 2014
A mediastinal mass was incidentally found on chest radiography in a 46-yr-old woman who had had myasthenia gravis (MG) for 2 months. Computed tomography revealed a 4-cm in size, well-defined, and lobulating mass with nodular calcification that was located in the thymus. Microscopically, the mass consisted of diffuse amorphous eosinophilic ...
Sánchez-Juan Pascual P From the Memory and Aging Center and Department of Neurology (P.S.-J., P.M.G., J.H., B.G., M.H., L.T.G., M.G.-T., W.W.S., A.L.B., H.J.R., J.H.K., B.L.M.,W.J.J., G.D.R.) and Department of Pathology and Laboratory Medicine (E.J.H.), University of California, San Francisco; University Hospital "Marqués de Valdecilla," IFIMAV and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (P.S.-J.), Santander, Spain; Helen Wills Neuroscience Institute (P.M.G., W.J.J., G.D.R.), University of California, Berkeley; Lawrence Berkeley National Laboratory (P.M.G., J.P.O., M.J., W.J.J., G.D.R.), Berkeley, CA; Center for Neurodegenerative Research (J.Q.T.), University of Pennsylvania, Philadelphia; and Department of Pathology and Laboratory Medicine (H.V.V.), University of California, Los - - 2014
To evaluate the effect of amyloid imaging on clinical decision making. We conducted a retrospective analysis of 140 cognitively impaired patients (mean age 65.0 years, 46% primary β-amyloid (Aβ) diagnosis, mean Mini-Mental State Examination 22.3) who underwent amyloid (Pittsburgh compound B [PiB]) PET as part of observational research studies and ...
Saggini A - - 2013
We report the unprecedented case of reactive eccrine syringofibroadenoma (ESFA) secondary to primary cutaneous amyloidosis. A 62-year-old woman of Asian ethnicity presented with a pruritic rash on the back of long-standing duration. Physical examination revealed diffuse hyperpigmentation localized to the interscapular region: there were a multitude of hyperpigmented macules merged ...
Castellani C C Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, - - 2014
Plaque hemorrhage, inflammation and microvessel density are key determinants of plaque vulnerability in native coronary atherosclerosis (ATS). This study investigates the role of intraplaque hemorrhage (IPH) and its relation with inflammation and microvessels in cardiac allograft vasculopathy (CAV) in posttransplanted patients. Seventy coronary plaques were obtained from 12 patients who ...
Babburi Suresh S Professor, Department of Oral & Maxillofacial Pathology, Drs. Sudha & Nageswara Rao Siddhartha Institute of Dental Sciences Chinaoutapally, Andhra Pradesh, India - - 2013
Amyloid involvement of the tongue is almost always secondary to systemic amyloidosis. Isolated amyloidosis of the tongue is relatively rare and it accounts for less than 9% of all types of amyloidosis. We are presenting a case of a 54-year-old male patient who complained of an enlarged tongue and bilateral ...
Lone Y A YA Department of Surgery, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, India. - - 2013
Hydatid disease is caused by a cestode, Echinococcus. Its intermediate hosts are herbivores but humans can be accidental hosts. Hydatid disease is endemic in some parts of America, Australia, the Mediterranean region, Central Asia, and Central and Eastern Europe. The organs most frequently affected by Echinococcus are the liver and ...
McMurrich William W The Foot and Ankle Service, Department of Trauma & Orthopaedic Surgery, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 5SU, United Kingdom. Electronic address: - - 2013
Background rheumatoid nodulosis is a rare disease characterised by multiple subcutaneous nodules, a high titre of rheumatoid factor, radiologically detectable cystic bone lesions, but with none or few of the systemic manifestations or joint activity of rheumatoid disease. Histopathologically, nodulosis is the same as the nodules found in rheumatoid arthritis. ...
Richards Gideon - - 2013
Sonoelastography is an emerging ultrasound-based technique that allows characterization of tissue stiffness. The aim of this report is to present a case of significant penile curvature with a non-palpable, non-sonographically visualized plaque that was demonstrable with sonoelastography. A 60-year-old male presented with significant left penile curvature during erections. The penis ...
Ness Molly J - - 2013
Langerhans cell histiocytosis (LCH) (previously called eosinophilic granuloma, Hand-Schüller-Christian syndrome, Letterer-Siwe disease, and Hashimoto-Pritzker disease) is a rare, heterogeneous disorder with highly variable presentation. LCH commonly affects the skin, as well as internal organs. Because the skin lesions appear benign, and LCH is unfamiliar to most physicians, diagnosis is often ...
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