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Jeng Michael R MR Division of Pediatric Hematology/Oncology/Stem Cell Transplantation/Cancer Biology, Stanford University School of Medicine, Palo Alto, - - 2014
We describe a child initially diagnosed with multi-focal infantile hemangioma (cutaneous, hepatic, pulmonary), a benign vascular lesion, which underwent malignant transformation to angiosarcoma. The use of anti-angiogenic agents, such as bevacizumab, an anti-vascular endothelial growth factor (VEGF) antibody, has been reported in adults with angiosarcoma. Treatment with chemotherapy (gemcitabine and ...
Attou Rachid - - 2014
Congenital cystic adenomatoid malformation, also named congenital pulmonary airway malformation (CPAM), is a congenital lung abnormality which is uncommon in adults. The usual radiological appearance of CPAM is a cystic space-occupying lesion. We present one case of CPAM with unusual clinical and radiological findings, a complicated spontaneous pneumothorax with intracystic ...
Arastu M H MH Queens Medical Centre, Nottingham, UK, - - 2014
Rupture of the anterior cruciate ligament (ACL) is a common injury, often presenting with a typical injury pattern. Historically, the literature indicates that the accuracy of diagnosis of ACL ruptures is poor at the initial medical consultation. The aims of this study were to determine: the mechanism of injury; changes ...
Warren Sian S Department Integrated Sexual Health, Cardiff Royal Infirmary, Cardiff, - - 2014
This case describes a young white British man with a one-year history of recurrent genital ulceration managed by the GP. Initially thought to be a drug reaction, however presentation at our genitourinary medicine clinic and onward review with dermatology allowed the diagnosis of Behçet's disease to be made. The clinical ...
Silk Hugh H Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA, USA. Electronic address: - - 2014
Oral pathologic abnormality is common and can be potentially serious. There are many diseases of the mouth that medical personnel must be able to diagnose and initiate management. The most prevalent lesions can be categorized as infectious, inflammatory, and common benign and malignant lesions. This article discusses prevalence, cause, diagnosis, ...
Spârchez Zeno Z 3rd Medical Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Institute of Gastroenterology and Hepatology, Department of Ultrasound, Cluj Napoca, Romania, Email: - - 2014
The introduction of microbubble contrast agents (CA), which act as blood pool tracers, has overcome the limitations of conventional B-Mode, colour or power Doppler ultrasound, enabling the display of parenchymal microvasculature. Initially, the use of CA was accepted for hepatic lesions. In the following years, experts have expanded recommendations, as ...
Tay T T Department of Pathology, Singapore General Hospital, 20 College Road, Level 10, Diagnostics Tower, The Academia, Singapore 169856. - - 2014
Clear cell chondrosarcoma is a rare cartilaginous tumour of low-grade malignancy. Although it has a characteristic histological appearance, its radiological features and clinical presentation often mimic a benign lesion. Herein, we describe the case of a patient with a clear cell chondrosarcoma of the right proximal femur that had an ...
Canter Debra D Texas Children's Hospital, Houston, - - 2014
In 1998, Sorof et al. reported 28% of 60 pediatric SLE patients had class V lesions on their first biopsy and 37% had class V lesions on their most recent biopsy. Although 19% of patients with LN transformed from other classes to class V, there were no patients with repeat ...
Flannigan Ryan Kendrick RK Department of Urological Sciences, University of British Columbia, Vancouver, - - 2014
One must entertain a broad differential diagnosis for infants presenting with gross hematuria. Initial workup includes urine analysis, serum laboratory values and abdominal ultrasound. We describe an infant presenting with gross hematuria found to have a calcified renal mass upon initial ultrasound and subsequent computed tomography scan. We considered a ...
Molter Christine M - - 2014
A 14-yr-old female Pesquet's parrot (Psittrichas fulgidus) presented for lethargy and decreased ability to fly. Physical exam was unremarkable. Blood work showed an elevated white blood cell count and a strong positive Aspergillus galactomannan titer. Empirical Aspergillus treatment was initiated with compounded generic itraconazole. Radiographs revealed an irregular osteolytic lesion ...
McKinley Lana H LH Largo Medical Center, Medical Education, 2025 Indian Rock Rd, Largo, FL 33774, USA. - - 2014
Microcystic adnexal carcinoma (MAC) is an uncommon, locally aggressive cutaneous neoplasm that usually presents as a slow-growing, asymptomatic lesion on the head or neck. Microcystic adnexal carcinoma frequently is misdiagnosed due to its histologic appearance on superficial biopsy specimens mimicking other follicular neoplasms. Herein, we highlight a case in which ...
Greenberg James A - - 2014
A 53 year old woman with fibroids was taken to the operating room for a hysterectomy. Initial laparoscopic inspection of the abdomen and pelvis revealed multiple black lesions on the peritoneal surfaces. An intra-operative biopsy confirmed the lesions to be ink staining. A hysterectomy was completed without incident. Post-operative investigation ...
Nougaret Stephanie S Department of Abdominal Imaging, Saint Eloi University Hospital, 80 avenue Augustin Fliche, 34295, Montpellier Cedex 5, France, - - 2014
To examine the natural history of incidentally detected pancreatic cysts and whether a simplified MRI protocol without gadolinium is adequate for lesion follow-up. Over a 10-year period, 301-patients with asymptomatic pancreatic cysts underwent follow-up (45 months ± 30). The magnetic resonance imaging (MRI) protocol included axial, coronal T2-weighted images, MR cholangiopancreatographic and fat ...
Kim Janet J Department of Dermatology, Royal Perth Hospital, Perth, Western Australia, - - 2014
Mycosis fungoides is the most common subtype of primary cutaneous lymphoma and has several clinical variants. We report a 74-year-old man presenting with an acquired palmoplantar keratoderma initially diagnosed and treated as psoriasis with suboptimal improvement. Several months later the patient developed patches and plaques that were histologically consistent with ...
Botana Rial Maribel M Unidad de Técnicas Broncopleurales, Complexo Hospitalario Universitario de Vigo, Vigo, Pontevedra, - - 2014
The evaluation of pleural effusion (PE) includes various techniques, including pleural biopsy (PB). Our aim was to study the diagnostic yield of Tru-Cut needle PB (TCPB) and to define clinical/radiological situations in which TCPB might be indicated as an initial procedure. Retrospective study of TCPB in a hospital centre (2010-2012). ...
Koshy A N AN William Buckland Radiotherapy Centre, Alfred Hospital, Melbourne, Victoria, - - 2014
Background: Less than 1 per cent of tumours occurring in the region encompassing the internal auditory canal and the cerebellopontine angle are malignant. Primary central nervous system melanomas arising from this region are exceptionally rare and are often initially misdiagnosed as acoustic neuromas. Methods: We present a 71-year-old man with ...
Kozłowska A A Division of Reproductive Biology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland, - - 2014
We revealed earlier that induction of ovarian cysts in gilts by dexamethasone phosphate disodium salt (DXM) administration from the follicular phase of the estrous cycle (EC) changed the cholinergic innervation of the gonad. In the present study, the innervation of porcine ovaries by vesicular acetylcholine transporter (VAChT)-, neuronal nitric oxide ...
Park V Y - - 2014
Purpose: The purpose of our study was to review and compare the US findings of synchronous malignant breast lesions other than the index cancer additionally detected on second-look US with those detected on initial US, and therefore to determine differing characteristics that may aid in diagnosis and essentially improve the ...
Rooijakkers M - - 2014
Endobronchial lipomas are extremely rare benign tumours of the lung. Their clinical presentation mimics that of obstructive lung diseases such as asthma and chronic obstructive pulmonary disease (COPD), leading to a delay in diagnosis and errors in treatment. Therefore, making precise diagnosis may be challenging. We report a case of a ...
Alam Muhammad Matloob - - 2014
Factor XIII (FXIII) deficiency is a rare (autosomal recessive) genetic disorder which is associated with delayed bleeding symptoms that occur hour or days after trauma. Spontaneous rupture of visceral organs due to FXIII deficiency is a rare cause of abdominal pain with grave consequences and can be easily confused with ...
Bakhshandeh Azam A Section for Cariology and Endodontics & Paedodontics and Clinical Genetics, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Alle, Copenhagen N, - - 2014
Studies examining the efficacy of sealing occlusal caries lesions in the primary dentition are limited, and no studies have so far examined the efficacy of infiltrating occlusal lesions on primary molar teeth. This study aimed to evaluate the efficacy of infiltrating, sealing, or fluoride varnishing on the occlusal surfaces with ...
Kang Ju Wan JW From the *Department of Otorhinolaryngology, College of Medicine, and †Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Seoul, - - 2014
Nasopalatine duct cyst is one of the most common cysts among the nonodontogenic cysts in the maxillofacial area. This lesion usually does not show specific symptoms except for pressure from large cysts or infectious symptoms. Surgical removal including the epithelial lining is considered the treatment of choice. There are few ...
Kim Soo-Yeon SY From the Department of Radiology and Research Institute of Radiological Science (S.Y.K., H.J.M., J.Y.K., E.K.K.), Department of Research Affairs (K.H.H.), and Department of Surgery (W.Y.C.), Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, 120-752 Seoul, - - 2014
Purpose To investigate the natural history of thyroid nodules found to be benign at initial fine-needle aspiration biopsy (FNAB) to determine the percentage of nodules that increased in volume by more than 50% as being an indicator of malignancy. Materials and Methods This retrospective observational cohort study was approved by ...
Iwamuro Masaya M Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan. Electronic address: - - 2014
The purpose of this study was to reveal the diagnostic accuracy of initial pathologic assessment of biopsied samples in patients with gastrointestinal follicular lymphoma lesions. A total of 48 patients with follicular lymphoma (Lugano system stage I: n = 30; II1: n = 4; II2: n = 4; IV: n ...
Shu Francy F Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, - - 2014
A 55-year-old man was seen with progressively worsening dizziness over 10 months. The initial assessment with unremarkable laboratory and imaging studies suggested a peripheral vestibular disorder. He was then lost to follow-up but later was seen with worsening ataxia. Additional imaging studies showed subtle parenchymal lesions in the posterior fossa. ...
Allaoui Mohamed M Department of Biopathology, François Baclesse Cancer Center, CAEN, - - 2014
Malignant pilomatricoma or pilomatrical carcinoma is a rare malignant hair follicle neoplasm. This tumor is locally aggressive with increased tendency to recur, but a low metastatic potential. Its histopathological diagnosis is difficult and based on a detailed evaluation of the infiltrative nature, the importance of the mummified and necrotic cell ...
Gorecka M M Interventional Respiratory Unit, Department of Respiratory Medicine, Galway University Hospitals, Galway, - - 2014
A 73-year-old man, non-smoker presented with an 8-week history of left-sided chest pain and shortness of breath on exertion. He had no significant medical history. He worked in construction for 40 years, but denied definite asbestos exposure. His initial chest X-ray demonstrated a large left-sided pleural effusion. Subsequent CT thorax ...
Creamer Andrew A Kings College Hospital, London, - - 2014
A 21-year-old man presented with a widespread, intensely pruritic skin rash, which developed acutely 5 days after returning from a backpacking holiday in Thailand. On initial presentation to his general practitioner, an erythematous, papular rash was noted in the upper right back, with smaller clusters of lesions on the buttocks ...
Mano Yoshinori Y Department of Cardiology, Tokyo Dental College, Ichikawa General Hospital, - - 2014
We herein report the case of a 69-year-old woman with left atrial myxoma detected following treatment with glucocorticoids for an initial diagnosis of polymyalgia rheumatica (PMR). The glucocorticoids markedly improved the patient's symptoms, and the tumor was excised after rapidly tapering the glucocorticoid dose. The PMR-like symptoms did not recur ...
Goedee Stephan S Department of Neurology, UMC Utrecht, Utrecht, The - - 2014
Ischaemic stroke as the initial presentation of systemic malignancy is reported infrequently and is characterised by ischaemic lesions that exceed the vascular territory of a single vessel. There is also a high rate of early stroke recurrence. Several pathophysiological mechanisms are known to cause cerebrovascular complications in malignancies, as a ...
Hashida Noriyasu N Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, - - 2014
To study a case with intraretinal Toxocara larvae in a granuloma using high-penetration optical coherence tomography (HP-OCT). A 50-year-old man, who was referred to our clinic with ocular toxocariasis, initially presented with granuloma formation in the retina. We followed the treatment-associated changes in the toxocariasis lesion by a series of ...
Aparna Manikkath M Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal, Karnataka, - - 2014
Endodontic diagnosis is challenging and depends on the organisation of information from the patient history, clinical examination and analysis of the pulp, radiographic and histopathological assessment. A 35-year-old man was endodontically treated for radiolucency in relation to the roots of maxillary central incisors as it was a provisionally diagnosed case ...
Pandey Deeksha D 0000-0002-8434-3961 Department of OBGYN, KMC, Manipal University (MU), Manipal 576104, - - 2014
With the help of this case we summarize some crucial features to be picked up from history and examination before labeling a case as Bartholin's abscess or cyst. A 20-year old unmarried girl, deaf and mute since birth, was initially diagnosed to have Bartholin's abscess. On careful reexamination after inflammation ...
Sherwani Rana K RK Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, UttarPradesh, - - 2014
Eosinophilic granuloma (EG) is a rare histiocytic disorder resulting from clonal proliferation of Langerhans cells. It accounts for less than 1% of all osseous neoplasms and has a predilection for involving the axial skeleton. Although suspicion of the disease may arise from clinical features and radiographic demonstration of destructive bone ...
Singh Manish Kumar MK Department of Surgery, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar, - - 2014
Mucocele of the appendix is an aseptic dilatation secondary to obstruction. The preoperative clinical diagnosis of appendiceal mucoceles can therefore be difficult because of this lack of clinical symptomotology. Surgical excision is the treatment of choice in benign mucocele. We report a case presenting to the surgeons where initial clinical ...
Cooksley Nathania N Department of Thoracic Medicine, Cairns Hospital, Cairns, Queensland, - - 2014
A 28-year-old woman of Laotian origin presented with dry cough, fevers, night sweats and weight loss over the preceding 6 weeks. Radiological investigations revealed large complex cavitary lesions in the middle and lower lobes of the right lung, with no mediastinal lymph node enlargement. Bronchoscopic investigations did not yield a ...
Kooblall Minesh M Department of Respiratory Medicine, Tallaght Hospital, Dublin City, - - 2014
A 70-year-old man, ex-smoker with a 3-pack-year smoking history, presented with a 5-week history of persistent cough. There were no positive findings on clinical examination. The patient's chest X-ray showed a nodular density in the right lung, initially thought to be malignant. After an extensive workup which included CT-guided lung ...
Ramaswamy Balakrishnan B Department of Otolaryngology-Head and Neck Surgery, Kasturba Medical College, Manipal, Manipal University, Karnataka, - - 2014
We report the case of a young woman who presented with progressive dysphagia and swelling in the anterior aspect of the neck of short duration. On evaluation, she was diagnosed with amelanotic malignant melanoma of the cervical oesophagus. She underwent total laryngopharyngo-oesophagectomy with gastric transposition with bilateral modified radical neck ...
Rejdak Robert R 0000-0003-3321-2723 Department of General Ophthalmology, Medical University of Lublin, 20-079 Lublin, Poland ; Medical Research Center of the Polish Academy of Sciences, 02-106 Warsaw, - - 2014
Introduction. We report a case of a male patient presented with sarcoid lesions of the iris and conjunctiva, mimicking tuberculosis due to epithelioid cell granulomas with small central necrosis in conjunctival biopsy. Patient. A 25-year-old man was referred to our department for further management of an "iris tumor with iridocyclitis" ...
Simon Jacob C JC Department of Preventive and Restorative Dental Sciences, University of California, San - - 2013
Early demineralization appears with high contrast at near-IR wavelengths due to a 10- to 20-fold difference in the magnitude of light scattering between sound and demineralized enamel. Water absorption in the near-IR has a significant effect on the lesion contrast and the highest contrast has been measured in spectral regions ...
Lee Seung Soo SS Department of Surgery, Catholic University of Daegu School of Medicine, 33 Duryugongwon-ro 17-gil, Nam-gu, Daegu 705-718, - - 2013
Primary gastric lymphoma is a rare gastric malignancy. Its diagnostic process is complex. Clinician may find initial diagnosis of primary gastric lymphoma unreliable, especially when it indicates the rarest subtype of gastric lymphoma, while its initial endoscopic presentation fails to raise the slightest suspicion of primary gastric lymphoma. A 53-year-old ...
Kelly J W JW Victorian Melanoma Service (VMS), The Alfred Hospital, Victoria, - - 2013
Recurrent naevi are widely recognized to occur commonly following incomplete removal of a melanocytic lesion. These lesions have been generally understood as representing benign imitators of melanoma. We report nine cases of recurrence of melanocytic lesions that were melanomas. The most suspicious clinical feature for melanoma in these cases was ...
Atalar Hakan - - 2013
Hemangioendotheliomas are vascular tumors which have an intermediate clinical behavior between hemangiomas and angiosarcomas. The epithelioid subtype of hemangioendothelioma, which is rarely seen in bone, has the potential to metastasize and may be confused radiologically with benign or malignant lesions. A metacarpal origin of this tumor is extremely rare. In ...
Strub Graham M GM School of Medicine, Virginia Commonwealth University, Richmond, VA, - - 2013
Sarcoidosis is a systemic inflammatory disease that can affect virtually every organ system, leading to a wide variety of clinical manifestations. Central nervous system involvement producing neurologic symptoms can occur in patients with sarcoidosis, yet rarely are these symptoms the initial manifestations of the disease. Here we present the case ...
Chen I-Hsuan - - 2013
Pemphigus vulgaris (PV) is an autoimmune disease in which the autoantibody, immunoglobulin G, is directed against the keratinocytes in the epidermis. The classic presentations of PV are flaccid vesicles or bullae over the oral mucosa, trunk, groin, and extremities. The age of onset is usually between 40 and 60 years, ...
Nou Eric - - 2013
Introduction:The optimal timing for repeat evaluation of a cytologically benign thyroid nodule >1cm is uncertain. Arguably, the most important determinant is the disease-specific mortality resulting from an undetected thyroid cancer. Presently, there exists no data which evaluate this important endpoint.Methods:We studied the long-term status of all patients evaluated in our ...
Cohen Seth M - - 2013
ObjectiveAccurate diagnosis of a voice disorder is an essential first step toward its appropriate treatment. We examined differences in laryngeal diagnosis over time in outpatients evaluated by primary care physicians (PCPs) and/or otolaryngologists.Study Design and SettingRetrospective analysis of data from a large, national administrative US claims database.Subjects and MethodsPatients with ...
Argyris Prokopios P - - 2013
Examples of multiple minor salivary gland tumors, synchronous or metachronous, are uncommon. We report a patient who initially presented with polymorphous low-grade adenocarcinoma (PLGA) and subsequently with myoepithelioma. A 91-year-old white woman presented in 2009 with a 1-cm, firm, nontender, well-circumscribed nodule of the left side of the upper lip ...
Kusaka Soichi - - 2013
Tumefactive fibroinflammatory lesion is an idiopathic fibrosclerosing disorder occurring in the head and neck region. It is one of a broad spectrum of entities named inflammatory pseudotumors and, as the name suggests, it mimics a lot of diseases such as malignancies or infections. Combined with its rarity, tumefactive fibroinflammatory lesion ...
Walker Amanda J - - 2013
We present an unusual case of a germinoma of the pineal region arising adjacent to an epidermoid cyst in a 16-year-old male. Initial imaging findings were classic for epidermoid cyst. The patient underwent two partial resections at an outside institution, each specimen demonstrating pure epidermoid cyst. Follow-up imaging over a ...
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