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Hammoud Ghassan M GM Ghassan M Hammoud, Ashraf Almashhrawi, Jamal A Ibdah, Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65212, United - - 2014
Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) of the liver is a safe procedure in the diagnosis and staging of hepatobiliary malignancies with a minimal major complication rate. EUS-FNA is useful for liver lesions poorly accessible to other imaging modalities of the liver. EUS-guided FNA of biliary neoplasia and malignant ...
Hachiya Hiroyuki H Hiroyuki Hachiya, Junji Kita, Takayuki Shiraki, Yukihiro Iso, Mitsugi Shimoda, Keiichi Kubota, Second Department of Surgery, Dokkyo Medical University, Tochigi 321-0293, - - 2014
We report a case of intraductal papillary neoplasm of the bile duct (IPNB) that developed in a patient with primary sclerosing cholangitis. A 46-year-old woman was admitted to our hospital with obstructive jaundice. The liver function tests demonstrated increased serum liver enzyme levels. Computed tomography showed dilatation of the intrahepatic ...
He Xiao-Dong XD Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, - - 2014
Background. Choledochal cysts are most common in Asian populations. In addition, the incidence of biliary tract malignancies from choledochal cysts is increasing, but the risk of carcinogenesis is still unclear. Material and methods. Clinical data from 214 congenital choledochal cyst cases from 1968 to 2013 were retrospectively analyzed. Results. Todani ...
Hua Rong R Department of Biliary-Pancreatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, - - 2014
Signet-ring cell carcinoma (SRCC) is rare in the biliary system. We report a case of SRCC coexisting with adenocarcinoma, arising in a choledochal cyst of the extrahepatic bile duct. The patient was a 52-year-old man, hospitalized for the investigation of jaundice and pruritus. Abdominal computed tomography and magnetic resonance cholangiopancreatography ...
Navaneethan Udayakumar U Section for Advanced Endoscopy and Pancreatobiliary Disorders, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Desk Q3, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH, 44195, USA, - - 2014
The role of M2-PK (pyruvate kinase) in bile has not been studied in comparison with brushings and carbohydrate antigen (CA) 19-9 in the diagnosis of malignant biliary strictures. To compare the diagnostic accuracy of biliary M2-PK with cytology and serum CA 19-9 METHODS: In this prospective cross-sectional study, bile was ...
Aishima Shinichi S Department of Pathology and Microbiology, Faculty of Medicine, Saga University, Saga, - - 2014
Morphologic features and neoplastic potentials of bile duct adenoma (BDA) and von Meyenburg complex (VMC)-like duct arising in chronic liver disease were unknown. Thirty-five BDAs and 12 VMC-like duct lesions were observed in 39 cases with chronic liver disease. BDAs were divided into the EMA-cytoplasmic type (n = 14) and ...
Subhash Raveendran R Department of Surgical Gastroenterology, Government Medical College, Thiruvananthapuram, Kerala, - - 2014
Biliary Tract Intraductal Papillary Mucinous Neoplasm (BT-IPMN) is a very rare entity, gradually emerging into attention as sporadic cases are being reported worldwide. In this brief report we discuss about such an entity from our part of the world, based on a case from our institution. A 47-year-old female was ...
Patel Prashant P School of Cancer Sciences, Vincent Drive, University of Birmingham, Birmingham, B15 2TT, UK, - - 2014
Various methods have been used to sample biliary strictures, including percutaneous fine-needle aspiration biopsy, intraluminal biliary washings, and cytological analysis of drained bile. However, none of these methods has proven to be particularly sensitive in the diagnosis of biliary tract malignancy. We report improved diagnostic accuracy using a modified technique ...
Liu L N LN Department of Medical Ultrasound, Shanghai Tenth People's Hospital of Tongji University, - - 2014
Purpose: To investigate the imaging features of intraductal papillary neoplasm in bile duct (IPNB) on baseline ultrasound and contrast-enhanced ultrasound (CEUS). Materials and Methods: The imaging features on baseline ultrasound and CEUS in 16 pathologically proven IPNB lesions in 15 patients were retrospectively analyzed. Real-time contrast specific modes and contrast ...
Onozawa Hisashi H 1 Department of Surgery and 2Department of Pathology, Hoshi General Hospital, Koriyama, - - 2014
Abstract We report a case of malignant melanoma of unknown primary origin presenting metastasis in various organs as well as intraluminal gallbladder bleeding due to gallbladder metastasis. A 58-year-old woman was diagnosed with stage IV metastatic malignant melanoma. Because she exhibited acute cholecystitis and hemobilia due to malignant melanoma of ...
Kawasaki Akiko - - 2014
BackgroundMeningeal carcinomatosis and hypercoagulability associated with malignancy are typical late stage complications in cancer patients. The co-occurrence of meningeal carcinomatosis and cerebral infarction related to hypercoagulability associated with malignancy in an individual as the initial manifestation of malignancy has not been previously reported.Case presentationHerein, we report the case of an ...
Coltrera Marc D MD Department of OTO-HNS, University of Washington, 1959 Northeast Pacific, Box 356515, Seattle, WA 98195, USA; OTO-HNS Division, VA Puget Sound, 1660 S Columbian Way, Seattle, WA 98108, USA. Electronic address: - - 2014
This article is intended to demystify the process for those with a potential interest in acquiring ultrasound skills. It is not intended to be a comprehensive review of head and neck ultrasound but, rather, is focused on the bare minimum requirements and considerations involved in clinician-performed ultrasound. The article covers ...
Burns Rebekah A RA Assistant Professor (Burns), *Division of *Emergency Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA; Assistant Professor of Pediatrics (Topoz), †Section of Emergency Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO; Medical Director, ‡Emergency Department and Associate Professor of Pediatrics (Reynolds) Division of Pediatric Emergency Medicine, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Chicago, - - 2014
Tumor lysis syndrome (TLS) is a potentially fatal complication of induction therapy for several types of malignancies. Electrolyte derangements and even downstream complications may also occur prior to the initial presentation to a medical provider, before an oncologic diagnosis has been established. It is therefore imperative that emergency physicians be ...
Yücesoy Ali Naki AN 1 General Surgery Department, 2 Radiodiagnostic Department, Batı Bahat Hospital, Istanbul, - - 2014
Intrabiliary rupture is the most frequently seen complication of the hepatic hydatid cysts. Obstructive jaundice can be seen as a complication of the intrabiliary ruptured hepatic hydatid cysts due to the migrated cystic content into bile ducts. In this study, we present two rare complications seen in a patient who ...
Choi Sang Hyun SH Department of Radiology, Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul, 138-736, - - 2014
To evaluate the role of core-needle biopsy (CNB) by comparing the results of CNB and repeated fine-needle aspiration (FNA) for thyroid nodules with initially non-diagnostic FNA results. From October 2008 to December 2011, 360 nodules - 180 consecutive repeated FNAs and 180 consecutive CNBs -- from 360 patients (83 men, ...
Friedrich Reinhard E RE Oral and Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany - - 2014
The lateral periodontal cyst (LPC) is a harmless developmental aberration derived from odontogenic epithelia lying between the roots of vital teeth. The exact histogenesis of LPC is a matter of debate but therapy is usually only required to maintain stable periodontal conditions and in case of evidence for growth of ...
Castoldi M C MC Department of Radiology, Ospedale CTO, via Bignami 1, 20162, Milan, Italy, - - 2014
Pulmonary Langerhans cell histiocytosis (PLCH) is a rare interstitial granulomatous disease that usually affects young adults who are smokers. Chest computed tomography (CT) allows a confident diagnosis of PLCH only in typical presentation, when nodules, cavitated nodules and cysts coexist and predominate in the upper and middle lungs. This article ...
Yip Linwah L Departments of *Surgery †Pathology ‡Endocrinology §Hematology/Oncology ¶Otolaryngology ‖Radiology, University of Pittsburgh Medical Center, Pittsburgh, - - 2014
To test whether a clinical algorithm using routine cytological molecular testing (MT) promotes initial total thyroidectomy (TT) for clinically significant thyroid cancer (sTC) and/or correctly limits surgery to lobectomy when appropriate. Either TT or lobectomy is often needed to diagnose differentiated thyroid cancer. Determining the correct extent of initial thyroidectomy ...
Lee Hwa H From the *Department of Ophthalmology, Korea University College of Medicine, Ansan; †Department of Ophthalmology, KEPCO Medical Center, Seoul; and ‡Department of Otolaryngology, Korea University College of Medicine, Ansan, South - - 2014
Primary paranasal sinus lymphoma is an uncommon malignancy that accounts for only 0.17% of all lymphomas and is often difficult to diagnose. Initially, tumors in this area cause very few symptoms and are at an advanced stage at the time of diagnosis. Ophthalmologic signs and symptoms occur early in the ...
Ide Fumio F Department of Diagnostic Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan, - - 2014
To reappraise the early history of odontogenic ghost cell lesions (OGCL), the extensive world literature published from 1838 to 1962 was reviewed. In light of the long history of OGCL, the term "calcifying epithelioma of Malherbe" first appeared in a 1931 French report, and the term "ghost cells" had its ...
Scheffer H J HJ Department of Radiology and Nuclear Medicine, VU University Medical Centre, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, - - 2014
Irreversible electroporation (IRE) is a new ablation technique that relies on high-voltage electrical pulses. This clinical study evaluates the pathological response of colorectal liver metastases (CRLM) treated with IRE and the clinical safety and feasibility. Ten patients with resectable CRLM were included. During laparotomy, the metastases were treated with IRE ...
Yu Chung Hoon CH Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of - - 2014
Gastric atypical cell (GAC), an indefinite pathologic finding, often requires repeated biopsy or other diagnostic treatments, such as endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), or operation (OP). The aim of this study was to analyze the initial endoscopic and histologic findings of GAC and to discuss the necessity ...
Papic Jonathan C JC Division of Pediatric Surgery, Department of Surgery, Indiana University School of Medicine, J W Riley Hospital for Children, Indianapolis, IN, - - 2014
Management of asymptomatic neonatal ovarian cysts varies. Some surgeons advocate initial observation, while others recommend immediate operation depending on cyst size and complexity. This study aims to compare outcomes of initial observation versus primary surgery, focusing on incidence of postnatal torsion and ovarian preservation. A retrospective study (1997-2012) of neonates ...
Fernandez Gomez Jesus M JM Servicio de Urología. Hospital Universitario Central de Asturias. Universidad de Oviedo. Oviedo. Asturias. - - 2014
To review the pathological criteria used to select patients for active surveillance, the optimization of biopsies and the role of confirmatory biopsy and of the transperineal approach. A bibliographic revision of the last years about active surveillance in prostate cancer as well as prostate biopsy, optimal rebiopsy protocols and transperineal ...
Goddard Lindsey - - 2014
Basal cell carcinoma (BCC) is the most common cutaneous malignancy, and usually presents on sun-exposed areas of the skin. Unsurprisingly, BCC appearing on the nipple-areola complex (NAC) is rare, and even more so in females and dark skin types. BCC of the NAC is more aggressive than other locations, thus ...
Ito F F Department of Obstetrics and Gynecology, Nara Medical University , Nara , - - 2014
Amniotic fluid embolism (AFE) is a rare clinical entity, sometimes fatal. A review was conducted to describe the frequency, diagnosis and pathophysiology of AFE. The reported incidences ranged from 1.9 cases per 100,000 maternities (UK) to 6.1 per 100,000 maternities (Australia), which can vary considerably, depending on the period, region ...
Pepper Christopher C Department of Otolaryngology - Head and Neck Surgery, Royal Surrey County Hospital , - - 2014
Abstract Conclusion: Computed tomography (CT) of the neck, chest, abdomen and pelvis is the most appropriate initial investigation following a fine needle aspiration cytology (FNAC) diagnosis of metastatic adenocarcinoma in cervical lymph nodes with unknown primary. PET-CT should be considered as the next step if the initial CT fails to ...
Han Min M Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Qingdao University, Qingdao, China - - 2014
To investigate the expression of eukaryotic initiation factor 4 E (eIF4E) in hypopharyngeal carcinoma compared with benign lesions, and the relationships between eIF4E expression and various clinicopathological parameters. Expression of eIF4E was analysed retrospectively in specimens from hypopharyngeal carcinomas and benign hypopharyngeal lesions using immunohistochemical staining and Western blotting. Tumours were ...
Song Won Seok WS Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, - - 2014
We assessed the plain radiographic characteristics of 10 cases of osteosarcomas during the initial painful period that had been overlooked by a primary physician. In addition, we evaluated chronologic changes in radiographic findings from initial symptomatic period to the time of accurate diagnosis. The clinical records were reviewed for clinical ...
Gokce Gokcen G Department of Ophthalmology, Sarikamis Military Hospital, Kars - - - 2014
Primary or secondary infiltration of the lacrimal drainage system by a lymphoid neoplasm is rare in children. Primary immunodeficiencies are characterized by occurrence of unusual malignancies at unexpected locations in the pediatric age group. Case report. A 12-year-old boy with a history of Bruton agammaglobulinemia and non-Hodgkin lymphoma (NHL) that ...
Eller Achim A Department of Radiology, University Hospital Erlangen, University of Erlangen-Nuremberg, Maximiliansplatz 1, 91054, Erlangen, Germany, - - 2014
This study was designed to assess efficacy and safety in the treatment of perivascular malignant liver lesions using percutaneous, computed tomography (CT)-guided irreversible electroporation (IRE). Fourteen patients (mean age 58 ± 11 years) with 18 malignant liver lesions were consecutively enrolled in this study. IRE was performed in patients not eligible for surgery ...
Salas-Alanis Julio Cesar JC Basic Science Department, School of Medicine, Universidad de Monterrey, Monterrey, Mexico ; Dystrophic Epidermolysis Bullous Research Association Mexico (DebRA Mexico A.C.), Monterrey, Mexico ; Department of Dermatology, University Hospital, Universidad Autonoma de Nuevo Leon, Monterrey, - - 2014
A 2-month-old female infant was referred to DebRA Mexico from the Regional Children's Hospital because of a generalized dermatosis from birth characterized by multiple blisters and erosions on the trunk, face and limbs, associated with minor trauma. A skin biopsy showing subepidermal blisters associated with a dermal infiltrate of Giemsa-positive ...
Arslan Selçuk S Department of Otorhinolaryngology, School of Medicine, Karadeniz Technical University, Trabzon, - - 2014
Wegener's granulomatosis (WG) is a rare necrotizing granulomatous vasculitis of unknown etiology commonly involving vessels, the upper and lower respiratory system and the kidneys. There are various symptoms and signs of WG due to a wide spectrum of involvement sites. The initial presentation of the disease as intraoral lesions is ...
Jeng Michael R MR Division of Pediatric Hematology/Oncology/Stem Cell Transplantation/Cancer Biology, Stanford University School of Medicine, Palo Alto, - - 2014
We describe a child initially diagnosed with multi-focal infantile hemangioma (cutaneous, hepatic, pulmonary), a benign vascular lesion, which underwent malignant transformation to angiosarcoma. The use of anti-angiogenic agents, such as bevacizumab, an anti-vascular endothelial growth factor (VEGF) antibody, has been reported in adults with angiosarcoma. Treatment with chemotherapy (gemcitabine and ...
Alsayyah Ahmed A *Department of Pathology, King Fahd University Hospital, University of Dammam, Dammam, Kingdom of Saudi Arabia; and †Department of Pathology, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi - - 2014
: Anaplastic large cell lymphoma (ALCL) is classified into systemic and primary cutaneous subtypes. A primary systemic ALCL present initially as cutaneous localized skin lesions is a rare presentation. We present an unusual case of a 13-year-old boy with systemic ALCL who presented with cutaneous nodules. The systemic nature of ...
Attou Rachid - - 2014
Congenital cystic adenomatoid malformation, also named congenital pulmonary airway malformation (CPAM), is a congenital lung abnormality which is uncommon in adults. The usual radiological appearance of CPAM is a cystic space-occupying lesion. We present one case of CPAM with unusual clinical and radiological findings, a complicated spontaneous pneumothorax with intracystic ...
Kim Jung Eun JE Department of Dermatology, School of Medicine, The Catholic University of Korea, Seoul, - - 2014
Angiosarcoma is a highly malignant vascular tumor of endothelial origin. Initially, a cutaneous manifestation presents as a singular or multifocal bruise-like patches on the skin, most frequently on the face, the scalp or the neck regions. On progression, the lesions become violaceous, and ill-defined spongy nodular tumors appear. Our patient ...
Chen Wei-Ting WT Department of Otolaryngology, Kaohsiung Armed Forces General Hospital, Kaohsiung 802, Taiwan, - - 2014
Malignancies, which present as deep neck abscesses are uncommon and may result in a delayed diagnosis or potentially a misdiagnosis. The present study describes a patient who exhibited a deep neck abscess as the initial manifestation of carcinoma of unknown primary (CUP). The aim of the present study was to ...
Khan Md Nuruzzaman MN Department of Neurosurgery, Sher e Bangla Medical College, Barisal, - - 2014
Metastatic tumors are the most common tumors of the spine, accounting for 98% of all spine lesions. But spinal cord compression as the initial presentation of metastatic occult follicular carcinoma without any thyroid enlargement is unusual and relatively rare. This report describes a 35-years-old female patient presenting with paraplegia and ...
Arastu M H MH Queens Medical Centre, Nottingham, UK, - - 2014
Rupture of the anterior cruciate ligament (ACL) is a common injury, often presenting with a typical injury pattern. Historically, the literature indicates that the accuracy of diagnosis of ACL ruptures is poor at the initial medical consultation. The aims of this study were to determine: the mechanism of injury; changes ...
Warren Sian S Department Integrated Sexual Health, Cardiff Royal Infirmary, Cardiff, - - 2014
This case describes a young white British man with a one-year history of recurrent genital ulceration managed by the GP. Initially thought to be a drug reaction, however presentation at our genitourinary medicine clinic and onward review with dermatology allowed the diagnosis of Behçet's disease to be made. The clinical ...
Asgary Saeed S Iranian Center for Endodontic Research, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
This article presents the successful surgical management of a failed mineral trioxide aggregate (MTA) orthograde obturation of a tooth with a history of impact trauma and perforated internal root resorption. A symptomatic maxillary lateral incisor with a history of perforation due to internal root resorption and nonsurgical repair using MTA ...
Silk Hugh H Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, MA, USA. Electronic address: - - 2014
Oral pathologic abnormality is common and can be potentially serious. There are many diseases of the mouth that medical personnel must be able to diagnose and initiate management. The most prevalent lesions can be categorized as infectious, inflammatory, and common benign and malignant lesions. This article discusses prevalence, cause, diagnosis, ...
Spârchez Zeno Z 3rd Medical Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Institute of Gastroenterology and Hepatology, Department of Ultrasound, Cluj Napoca, Romania, Email: - - 2014
The introduction of microbubble contrast agents (CA), which act as blood pool tracers, has overcome the limitations of conventional B-Mode, colour or power Doppler ultrasound, enabling the display of parenchymal microvasculature. Initially, the use of CA was accepted for hepatic lesions. In the following years, experts have expanded recommendations, as ...
Tay T T Department of Pathology, Singapore General Hospital, 20 College Road, Level 10, Diagnostics Tower, The Academia, Singapore 169856. - - 2014
Clear cell chondrosarcoma is a rare cartilaginous tumour of low-grade malignancy. Although it has a characteristic histological appearance, its radiological features and clinical presentation often mimic a benign lesion. Herein, we describe the case of a patient with a clear cell chondrosarcoma of the right proximal femur that had an ...
Flannigan Ryan Kendrick RK Department of Urological Sciences, University of British Columbia, Vancouver, - - 2014
One must entertain a broad differential diagnosis for infants presenting with gross hematuria. Initial workup includes urine analysis, serum laboratory values and abdominal ultrasound. We describe an infant presenting with gross hematuria found to have a calcified renal mass upon initial ultrasound and subsequent computed tomography scan. We considered a ...
Molter Christine M - - 2014
A 14-yr-old female Pesquet's parrot (Psittrichas fulgidus) presented for lethargy and decreased ability to fly. Physical exam was unremarkable. Blood work showed an elevated white blood cell count and a strong positive Aspergillus galactomannan titer. Empirical Aspergillus treatment was initiated with compounded generic itraconazole. Radiographs revealed an irregular osteolytic lesion ...
McKinley Lana H LH Largo Medical Center, Medical Education, 2025 Indian Rock Rd, Largo, FL 33774, USA. - - 2014
Microcystic adnexal carcinoma (MAC) is an uncommon, locally aggressive cutaneous neoplasm that usually presents as a slow-growing, asymptomatic lesion on the head or neck. Microcystic adnexal carcinoma frequently is misdiagnosed due to its histologic appearance on superficial biopsy specimens mimicking other follicular neoplasms. Herein, we highlight a case in which ...
Shu Francy F Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, - - 2014
A 55-year-old man was seen with progressively worsening dizziness over 10 months. The initial assessment with unremarkable laboratory and imaging studies suggested a peripheral vestibular disorder. He was then lost to follow-up but later was seen with worsening ataxia. Additional imaging studies showed subtle parenchymal lesions in the posterior fossa. ...
Pandit Sudipta - - 2014
Tuberculosis (TB) is the most common cause of cervical lymphadenopathy in the TB-endemic zone, like India but it can also mimic other diseases. Four cases of cervical lymphadenopathy presented to us as initial treatment failure after completion of six months of antitubercular drugs (ATD), including rifampicin, isoniazid, pyrazinamide, and ethambutol. ...
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