Search Results
Results 201 - 250 of 1723
< 1 2 3 4 5 6 7 8 9 10 >
Vrabie Camelia Doina - - 2009
Diffuse sclerosing variant (DSV) is a rare variant of papillary thyroid carcinoma (PTC) and its features have not yet been fully characterized. The aim of this case report is to analyze the immunohistochemistry profile of this disease and to highlight this rare entity. We analyzed the histology and immunohistochemistry of ...
Mihai Radu - - 2009
BACKGROUND: Fine-needle aspiration (FNA) biopsy is the cornerstone of assessment of thyroid nodules. Cytological criteria for benign (THY2) and malignant (THY5) aspirates are well established and reliable. When cytology suggests a follicular neoplasm (THY3), only formal histological assessment can differentiate between benign and malignant lesions. The objective of this study ...
El Demellawy Dina - - 2009
Diagnosis of papillary thyroid carcinoma (PTC), in many but not all cases, is an easily achievable diagnosis with almost minimal interobservable variability between pathologists. However, some cases of PTC, particularly the follicular variant, are quite challenging and show wide interobservable variability even among expert thyroid pathologists. Since proper diagnosis of ...
Aghaghazvini Leila - - 2009
A thyroglossal duct cyst is the most common congenital anomaly of the thyroid gland and midline masses in childhood (70% abnormality in childhood, 7% in adult). Carcinomas arising from a thyroglossal duct cyst are rare (only 1% of thyroglossal duct cyst cases) and characterized by relatively non-aggressive behavior and rare ...
Chen G - - 2009
OBJECTIVE: To investigate the clinical and pathological characteristics of thyroid nodules, as well as to evaluate the significance of ultrasonographically detected thyroid calcification in the diagnosis of thyroid carcinomas. METHODS: Retrospective data were studied from 1,051 consecutive patients who underwent a thyroidectomy in the Provincial Hospital of Fujian Medical University ...
Vano-Galvan Sergio - - 2009
An 80-year-old woman presented with an abrupt onset of asymptomatic black-to-purple discoloration of her right limb that appeared just before a thyroid gammagraphy. No antecedent of trauma was found. On questioning, patient admitted she did not cooperate during intravenous administration of Tc-99m-pertechnetate. Based on the abrupt onset of lesions and ...
Stang Michael T - - 2009
PURPOSE OF REVIEW: To provide an update on potential predictors of thyroid malignancy and how their use may alter clinical management. RECENT FINDINGS: As thyroid nodules become more prevalent clinicians are increasingly impelled to identify the optimal predictor(s) of thyroid malignancy, with the goal of guiding management based on assessed ...
Cakir Mehtap - - 2009
Thyroid hemiagenesis is a rare congenital anomaly in which one of the thyroid lobes with or without isthmus fails to develop. Here we present a woman patient with thyroid hemiagenesis, Graves' disease and ophthalmopathy with nodular goiter. Fine needle aspiration biopsy of the dominant nodule was suspicious of malignancy. The ...
Souza Ilana A - - 2009
The fine needle biopsy is an important minimally invasive procedure for providing accurate diagnosis in cases of thyroid gland nodules. This paper presents the research, development and evaluation of a virtual reality simulator for the training of ultrasound guided needle biopsy of thyroid gland nodules, using 3D models and haptic ...
Grodski Simon - - 2009
PURPOSE OF REVIEW: There is a worldwide increasing incidence of thyroid cancer, mostly due to the increased diagnosis of papillary microcarcinoma (PMC). This review examines its clinical significance and optimal treatment. RECENT FINDINGS: It is unclear whether or not the increase in PMC is real, or is simply due to ...
Kung Brian - - 2009
The thyroid gland is a relatively uncommon site for a secondary malignancy; even less common is a case of malignant melanoma metastatic to the thyroid. We describe the case of a 68-year-old man who presented with a neck mass in the posterior triangle. Fine-needle aspiration biopsy (FNAB) identified the mass ...
Adamidou Alexandra - - 2009
We present the case of a patient who presented with anaplastic thyroid carcinoma with a solitary large liver metastasis. Hepatic metastases are extremely rare in anaplastic thyroid carcinoma. We report the case of a 78-year old Greek man who presented with voice hoarseness, dyspnoea and a large mass on the ...
Engel Peter A - - 2009
An elderly, demented man with stable κ bi-clonal gammopathy of unknown significance suffered a severe displaced right humeral fracture in a fall. One week later a rapidly enlarging head, neck and axillary adenopathy first appeared, including a 2 cm tonsillar node that partially obstructed the oropharynx. A left cervical node ...
Kanai Toshiharu - - 2009
BACKGROUND: The measurement of serum thyroglobulin (Tg) is widely used as a marker for recurrence of thyroid carcinoma following total thyroidectomy. However, this method cannot differentiate between benign and malignant disease. We focused on the sugar chain in the Tg molecule and investigated the usefulness of Lens culinaris agglutinin (LCA)-reactive ...
González-García Raúl - - 2008
The appearance of a solitary lateral cervical cystic mass as the only initial presenting symptom of occult thyroid carcinoma is uncommon. Its presence is often misdiagnosed due to the more frequent branchial cyst in young people. Although oronasopharyngeal squamous cell carcinoma has been reported as the main cause of lymph ...
Rossi Esther Diana - - 2008
BACKGROUND: Fine needle aspiration cytology represents the most important tool in the diagnosis of thyroid nodules, mostly in discriminating malignant from benign lesions. The diagnosis of medullary thyroid carcinoma (MTC) may present some problems related to its deceptive morphologic picture. This diagnosis may be supported by immunocytochemistry (ICC), which may ...
Rocha Filho Francisco Dário - - 2008
Capillary thyroid carcinoma (PTC) is the most common neoplasm of thyroid. It usually grows slowly and is clinically indolent; although rare, its aggressive forms with local invasion or distant metastases can occur. Metastatic thyroid carcinoma rarely involves the orbit. We reported an uncommon case of orbital metastasis of PTC. A ...
Porterfield John R JR - - 2008
BACKGROUND: With increasing use of thyroid ultrasonography, thyroid nodules have been found to be extremely common. For over 25 years, fine needle aspiration (FNA) has been the pivotal diagnostic test to discriminate benign from potentially malignant thyroid nodules. Recently, false negative rates exceeding 10% have led to recommendations that thyroid ...
Baisakhiya Nitish Kumar - - 2008
Ganglioneuroma (GN) has a neuroectodermic origin and is localized along the sympathetic trunk. GN of the neck is a rare tumour and due to proximity to the thyroid gland, clinically and radiologically, these lesions can be mistaken as thyroid swellings. Definite diagnosis only can be suspected after surgical exploration and ...
Fernandez Nicole J - - 2008
: A 14-year-old male Labrador Retriever was presented for lethargy and collapse. On physical examination, numerous abnormalities were found, including a large ventral neck mass (100 cm(3)) in the area of the thyroid gland. Fine-needle aspirates revealed 2 apparent populations of cells: one suspected to be a well-differentiated thyroid carcinoma, ...
Yegen Gülçin - - 2009
CD10-common acute lymphoblastic leukemia antigen is a membrane-bound zinc metalloproteinase that is expressed by different hematopoietic cell types at unique stages of lymphoid and myeloid differentiation. It was reported to be expressed in various nonlymphoid cells and tissue, as well as in various types of neoplasms. Recently, it has been ...
Zhang Yixun A - - 2009
We present a rare case of a lateral ventricle choroid plexus metastasis arising from thyroid carcinoma in a 62-year-old man. The patient underwent subtotal excision of the intracranial tumour followed by total thyroidectomy with good outcome. We review previous reports of intracranial thyroid metastases and discuss the role of surgical ...
Sherman Jessica F - - 2008
OBJECTIVE: To assess the cytologic criteria for distinguishing neoplastic from nonneoplastic follicular cell and Hürthle cell thyroid lesions. STUDY DESIGN: Ten previously described and commonly used cytologic criteria were evaluated and graded on a 0-4 scale in a consecutive series of thyroid fine needle aspirations (FNAs) reported as follicular or ...
Stringaris Kate - - 2008
A diagnosis of myelodysplastic syndrome, refractory anemia subtype, was made in an elderly Indian woman on the basis of a refractory macrocytic anemia with normal vitamin B(12) and folate assays, normal thyroid function, essentially normal liver function and normal cytogenetic analysis. Disease evolution revealed that the diagnosis was erroneous.
Masood Rehan - - 2008
We are reporting a case of a young female, who presented to emergency room with sudden increase in thyroid swelling, high fever and acute respiratory distress. Clinical diagnosis of spontaneous infection of thyroid cyst was made. Operative finding was infection of thyroid cyst with gas formation. Systemic antibiotics and operative ...
Elsheikh Tarik M - - 2008
Distinguishing follicular variant of papillary carcinoma (FVPC) from follicular adenoma and follicular carcinoma can be difficult if nuclear features of papillary carcinoma are not well developed or only focally present. We assessed interobserver and intraobserver agreement among 6 thyroid experts by using 15 cases in which original pathologists suspected FVPC. ...
Vankalakunti Mahesha - - 2008
BACKGROUND: Metastatic tumors of thyroid are uncommonly reported from fine needle aspiration (FNA), although well documented in autopsy series. Soft tissue sarcomas metastasizing to the thyroid are even rarer. CASE: A 30-year-old woman who was nown to have malignant fibrous histiocytoma arising in the soft tissues of the medial aspect ...
Schoedel Karen E - - 2008
Ultrasound-guided sampling of the thyroid represents a standard diagnostic procedure in the evaluation of thyroid nodules. The two techniques typically used are fine-needle aspiration and fine-needle capillary biopsy. Each has been used with success in various body sites. Recently, a comparison of these two techniques showed no significant difference with ...
Reid-Nicholson Michelle - - 2008
We report a case of papillary thyroid carcinoma (PTC) and chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma of the thyroid gland. To the best of our knowledge, this is the first such case to be reported in the cytology literature. An 81-year-old male with known CLL presented for routine physical examination ...
Choi Hojin - - 2008
It is well known that thymoma is often associated with myasthenia gravis. Although ectopic thymoma can be found anywhere from the pharynx to the anterior mediastinum, it is usually benign and has not been reported in association with myasthenic symptoms. Moreover, ectopic thymoma located in the neck region is apt ...
Linkov Faina - - 2008
Thyroid cancer incidence is increasing, and its diagnosis can be challenging. Fine needle biopsy, the principal clinical tool to make a tissue diagnosis, leads to inconclusive diagnoses in up to 30% of the cases, leading to surgery. Advances in proteomics are improving abilities to diagnose malignant conditions using small samples ...
Iavazzo C - - 2008
We present the case of a 53-year-old lady with incidental diagnosis of struma ovarii 10 years after total thyroidectomy due to papillary thyroid carcinoma. The disease was diagnosed owing to high levels of serum thyroglobulin. The patient underwent exploratory laparotomy with total hysterectomy and bilateral salpingo-oophorectomy. Close follow-up was proposed ...
Osamura Robert Y - - 2008
In this review article, current trends in thyroid and parathyroid frozen sections are discussed. In Japan and other countries, the numbers of thyroid frozen sections have been dramatically decreasing over the past decade. The decline in the number of thyroid frozen sections has been attributed to two major factors: highly ...
Netea-Maier Romana T - - 2008
A persistent increase in incidence of thyroid carcinoma (TC) has been reported worldwide. The aim of our study was to assess trends in incidence and mortality of TC in The Netherlands between 1989 and 2003 and to examine whether these trends correlate with changes in diagnostic practices such as changes ...
Zendah Ines - - 2008
Thyroid tuberculosis is a rare disease even in countries in which tuberculosis (TB) constitutes an endemic disorder. The diagnosis is often difficult as the clinical presentation has no distinct characteristics. We report a 47-year-old woman who presented with a painful nodular swelling of the neck, confirmed by physical examination and ...
Inohara Hidenori - - 2008
In order to address whether galectin-3 in the sera and fine needle aspirates serve as a diagnostic marker distinguishing between benign and malignant thyroid nodules, we developed an enzyme-linked immunosorbent assay. We quantified galectin-3 in fine needle aspirates from a series of 118 patients with thyroid nodules and serum galectin-3 ...
Dionigi Gianlorenzo - - 2009
BACKGROUND: Studies have investigated delays in the diagnosis of neoplasms to identify delays to treatment on the part of patients and primary care practitioners. The aim of the current study was to evaluate the time interval (TI) required for the diagnosis of symptomatic papillary thyroid carcinoma (PTC). METHODS: The study ...
Shibru Daniel - - 2008
BACKGROUND: A 3-gene (PCSK2, PLAB, CCND2) assay has been reported to have high accuracy for distinguishing benign from malignant thyroid tumors that are often indeterminate on fine-needle aspiration (FNA) biopsy. The aim of the current study was to determine the diagnostic accuracy of the 3-gene assay in thyroid tissue and ...
Sahin Afsun - - 2008
A 16-year-old girl was admitted with severe bilateral conjunctival hyperemia and stinging lasting for more than 1 year. Slit-lamp biomicroscopic examination revealed extremely thickened corneal nerves and multiple small plexiform subconjunctival neuromas. Both eyes had thickened upper and lower eyelids and a neuroma was found on the left upper conjunctival ...
Megremis Stylianos - - 2008
An 11-year-old boy under suppression therapy for a solitary thyroid nodule was referred for sonographic examination. The diagnosis had been made at another institution, based only on sonography without cytopathologic verification. A small fusiform lesion, which was homogeneously hypoechoic with diffuse bright internal echoes, was demonstrated in the right lower ...
Roh Jong-Lyel - - 2008
BACKGROUND: Benign thyroid cysts have been successfully treated with nonoperative sclerotherapy. Although OK-432 is a safe and effective sclerosing agent used to treat benign cystic lesions, little is known about its effectiveness in thyroid cysts. This study tested the efficacy of OK-432 sclerotherapy for thyroid cysts. METHODS: This was a ...
Kang Sang-Wook - - 2008
Black thyroid is an uncommon phenomenon of black pigmentation of thyroid parenchyma induced by chronic minocycline therapy. Thyroid tumors associated with black pigmented thyroid are rare. We describe here a 42-year-old woman with a black thyroid associated with hyalinizing trabecular tumor (HTT). The patient presented with a palpable left-sided thyroid ...
Donatini G - - 2009
INTRODUCTION: Nodular lesions within the neck may origin from several structures. A misdiagnosed origin may expose the surgeon to inappropriate procedures. These lesions are paradoxically frequent in high specialised centre for endocrine surgery. PATIENTS AND METHODS: In the year 2006, three patients were first admitted to our department with a ...
Kim Min Jung - - 2008
OBJECTIVE: The purpose of this study was to determine which types of macrocalcifications are associated with thyroid carcinoma and to assess the role of other suspicious sonographic findings in thyroid nodules with macrocalcifications. METHODS: Our Institutional Review Board approved this retrospective study, and informed consent was not required. We reviewed ...
Kwak Jin Young - - 2008
OBJECTIVE: The purpose of this study was to evaluate the risk of malignancy of thyroid incidentalomas detected on (18)F-FDG PET and the diagnostic accuracy of sonography for differentiating benign from malignant focal thyroid incidentalomas that were detected on FDG PET. MATERIALS AND METHODS: Retrospective review was performed of a database ...
Tong Guo-Xia - - 2008
Primary osteosarcoma of the thyroid is an extremely rare tumor, with only 27 well-documented cases reported in the literature, including only one in the cytology literature. We describe here an additional case with fine-needle aspiration biopsy findings. A 60-year-old woman presented with a 1-month history of progressive midline neck swelling. ...
Montone Kathleen T - - 2008
CONTEXT: Hürthle cells are eosinophilic, follicular-derived cells that are associated with a variety of nonneoplastic and neoplastic thyroid lesions. The differential diagnosis of Hürthle cell lesions is quite broad. OBJECTIVE: To review the pathologic conditions associated with Hürthle cells in the thyroid and to discuss pathology of thyroid lesions associated ...
Asioli Sofia - - 2009
An exponential increase in the detection of papillary thyroid microcarcinomas (PTMCs) has been observed in recent times, possibly because of recent improvements in the management of thyroid lesions and extensive histological examination. However, no definitive treatment guideline has been developed for PTMC, resulting in patients undergoing overtreatment. In 2003, the ...
Agarwal Shweta - - 2008
In April 2006, a 55-year-old female presented with a thyroid mass and multiple skin nodules on scalp, forehead and neck. Fine needle aspiration cytology of thyroid mass and multiple skin nodules show tumor cells clusters in a repetitive microfollicular pattern on May-Grunwald-Giemsa stain suggestive of follicular thyroid carcinoma with metastasis ...
Chrisoulidou Alexandra - - 2008
Ectopic production of CRH by a medullary thyroid carcinoma or its metastases is a rare cause of ectopic Cushing's syndrome (ECS). We report a 45-year old male with medullary thyroid carcinoma (MTC), who, 24 years following the initial diagnosis, presented with clinical and biochemical evidence of an ACTH dependent Cushing's ...
< 1 2 3 4 5 6 7 8 9 10 >