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Poole Raewyn M RM Springer, Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand, - - 2014
Belinostat [Beleodaq(®) (US)], a small-molecule hydroxamate-type inhibitor of class I, II and IV histone deacetylase (HDAC) enzymes, has been developed by TopoTarget and Spectrum Pharmaceuticals for the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL). Belinostat has received its first global approval as monotherapy for this indication in the ...
Bartholome Lindsay T LT Department of Psychiatry, University of Minnesota Medical School, F282/2A West, 2450 Riverside Avenue, Minneapolis, MN 55454, - - 2013
Research has demonstrated significant underreporting of food intake in obese individuals with and without binge eating disorder (BED). An improved understanding of the accuracy of self-reported food intake is central to diagnosis of eating disorders and monitoring response to treatment. The purpose was to: (1) confirm those with BED consume ...
Bime Christian - - 2012
Broad dietary patterns have been linked to asthma but the relative contribution of specific nutrients is unclear. Soy genistein has important anti-inflammatory and other biological effects that might be beneficial in asthma. A positive association was previously reported between soy genistein intake and lung function but not with asthma exacerbations. ...
Serra Dolors D Department of Biochemistry and Molecular Biology, Facultat de Farmàcia, Universitat de Barcelona, Institut de Biomedicina de la Universitat de Barcelona IBUB, Barcelona, - - 2013
Current lifestyles with high-energy diets and little exercise are triggering an alarming growth in obesity. Excess of adiposity is leading to severe increases in associated pathologies, such as insulin resistance, type 2 diabetes, atherosclerosis, cancer, arthritis, asthma, and hypertension. This, together with the lack of efficient obesity drugs, is the ...
Wadikar D D - - 2012
Appetite has recently received the attention of researchers in developing countries due to the increasing prevalence of obesity. There are multiple complex mechanisms involved in food intake. The satiety level and the physiological state of a person are responsible for appetite expression. Specific manipulations of macronutrients have the potential to ...
Bales Connie W - - 2012
Our study characterizes food and energy intake responses to long-term aerobic training (AT) and resistance training (RT) during a controlled 8-month trial. In the STRRIDE-AT/RT trial, overweight/obese sedentary dyslipidemic men and women were randomized to AT (n = 39), RT (n = 38), or a combined treatment (AT/RT, n = ...
Oka Roberta K - - 2012
Peripheral Arterial Disease (PAD) is most prevalent in the elderly and associated with increased cardio vascular disease (CVD) morbidity and mortality. Treatment focuses on improving functional capacity and reducing CVD risk factors. To date, little is understood about dietary habits and weight in this patient population. Nutritional and weight recommendations ...
Speakman John R - - 2012
Work on obesity is evolving, and obesity is a consequence of our evolutionary history. In the space of 50 years, we have become an obese species. The reasons why can be addressed at a number of different levels. These include separating between whether the primary cause lies on the food ...
Qin Bo B University of North Carolina, Chapel Hill, - - 2012
To examine the cross-sectional association between dietary magnesium intake and radiographic knee osteoarthritis (OA) among African American and white men and women. The presence of radiographic knee OA was examined among participants from the Johnston County Osteoarthritis Project and was defined as a Kellgren/Lawrence grade of at least 2 in ...
Pearce Jo - - 2012
OBJECTIVE: To compare the key differences between school lunches and packed lunches as eaten in eleven secondary schools in England, 21 months after the food-based standards for school lunch became mandatory, but before the introduction of nutrient-based standards. DESIGN: Data on 358 school lunches and 139 packed lunches were collected ...
Golley R K - - 2012
BACKGROUND/OBJECTIVES:The effect of changing one aspect of diet needs to be considered within the context of total diet. The study aim was to evaluate the changes in children's overall food intake following replacement of regular-fat with reduced-fat dairy foods.SUBJECTS/METHODS:Secondary analysis of a cluster Randomized Controlled Trial where families were received ...
Scognamiglio U - - 2012
BACKGROUND: Malnutrition in hospitalised patients is often underestimated. The present study aimed to evaluate the validity of a questionnaire for the semi-quantitative evaluation of food intake compared to weighed records in patients who were hospitalised for the rehabilitation of neurological disorders. METHODS: Food intake at breakfast, lunch and dinner was ...
Cunningham Timothy J - - 2012
Food insecurity has detrimental effects on the mental, physical, and behavioral health of developing children. Few studies, however, have sought to determine whether associations exist between food insecurity and intake of vegetables, fresh or canned fruit, candy or cookies, French fries, fast food, water, milk, fruit juices, fruit drinks, soda, ...
Poskitt E M E - - 2012
Early diet and nutrition may set in place growth patterns and/or metabolic pathways that promote risk factors for later NCDs. Most relevant studies so far available have a cross-sectional or retrospective design and are thus of limited validity for evaluating the impact of early feeding on later disease. Standardised protocols ...
Palfreyman Zoe - - 2012
This study aimed to develop a self-report questionnaire to explore parental modelling of eating behaviours and then to use the newly developed measure to investigate associations between parental modelling with healthy and unhealthy food intake in both mothers and their children. Mothers (n = 484) with a child aged between 18 months ...
Kris-Etherton Penny M - - 2012
Because of efforts to decrease trans fatty acids (TFA) in the food supply, intake should be assessed in the population to establish a baseline TFA intake. The 1999-2002 National Health and Nutrition Examination Survey (NHANES) was used to identify a benchmark for TFA intake. TFA was estimated by mean, median, ...
Ni Hong-Gang - - 2012
The present study measured eight PBDE congeners' (BDE-28, 47, 99, 100, 153, 154, 183, and 209) exposure via ingestion of indoor dust and soil, inhalation, and food consumption. Contributions to PBDEs exposure from different media revealed that indoor dust (dust suspended in air) was not an important exposure route for ...
Burrows T - - 2012
Assessing dietary intake is important in evaluating childhood obesity intervention effectiveness. The purpose of this review was to evaluate the dietary intake methods and reporting in intervention studies that included a dietary component to treat overweight or obese children. A systematic review of studies published in the English language, between ...
Pakseresht Mohammadreza - - 2012
OBJECTIVE: To assess the validity of a 161-item quantitative FFQ (QFFQ) that was developed to evaluate dietary risk factors for a colorectal adenoma case-control study. DESIGN: A cross-sectional validation study of the QFFQ against 4 d food diary using Pearson correlation coefficients, cross-classification, weighted κ statistics and Bland-Altman plotting. SETTING: ...
Wirtshafter David - - 2012
Previous work has demonstrated that injections of the γ-aminobutyric acidA (GABAA) agonist muscimol into the nucleus accumbens shell (AcbSh) induce pronounced increases in the intake of solid foods and sucrose solutions, but do not potentiate water intake. In order to clarify the range of situations in which inactivation of the ...
Forster Sarah E - - 2012
OBJECTIVES: To determine the effect of a dietary intervention and micronutrient supplementation on self-reported infections in older adults. DESIGN: A randomized, placebo-controlled intervention trial. SETTING: Community living older people in South Yorkshire, United Kingdom. PARTICIPANTS: Two-hundred seventeen older adults aged 65 to 85. INTERVENTION: Participants were randomized to a dietary ...
Erinosho Temitope O - - 2012
OBJECTIVE: To evaluate whether food behaviours of parents are associated with children's dietary intakes outside the child-care setting, and to compare children's dietary intakes at home with foods and beverages consumed when they are at child-care centres. DESIGN: In 2005-2006, a survey was completed by parents of at least one ...
Temple Norman J - - 2012
Buffets are the "perfect" environment for facilitating excessive energy intake. Customers at buffets often eat considerably more food than is the usual case at regular restaurants. However, extremely little research has been conducted on the relationship between buffets, energy intake, and weight gain. Research studies are therefore needed that investigate ...
Smith Claire - - 2012
OBJECTIVES: Financial constraint is the underpinning determinant of household food insecurity; however, there has been little research examining the impact that increasing the 'money available' to food-insecure households could have on food purchasing. The main objective of the present study was to examine the effect of additional money (in the ...
Rodríguez-Bernal Clara L - - 2012
OBJECTIVE: To assess food and nutrient intakes and compliance with nutritional recommendations in pregnant women according to selected sociodemographic characteristics. DESIGN: Cross-sectional study based on data from the INMA-Valencia cohort (Spain), which recruited pregnant women between 2004 and 2005. Information on maternal sociodemographics and anthropometry was collected. Dietary intake was ...
Sioen Isabelle - - 2012
Numerous studies have indicated that for phthalates, the intake of contaminated foods is the most important exposure pathway for the general population. Up to now, data on dietary phthalate intake are scarce and - to the authors' knowledge - not available for the Belgian population. Therefore, the purpose of this ...
Son Min-Hui - - 2012
The dietary intake of polychlorinated biphenyls (PCBs) was estimated using the sum of 62 PCB congeners (∑(62)PCBs), including seven indicator PCBs and 12 dioxin-like PCBs, in the South Korea. In this study, 200 individual food samples belonging to 40 different foodstuffs were investigated to estimate the distribution of PCB congeners ...
Marinangeli Christopher P F - - 2012
Pulses have been identified as important components of a healthy diet. Assessment of pulse grains' nutritional composition alongside data from available preclinical and clinical trials suggests that pulses can modulate biological processes that lead to obesity. Components of pulse grains, including pulse-derived fibre and resistant starch, have been shown to ...
Kanerva Noora - - 2012
Subjects with higher preference for evening hours in daily activities (eveningness) have been repeatedly shown to practice adverse health behaviors as compared to those preferring morning hours (morningness). However, associations between chronotype and dietary intake have not been explored intensively. The authors explored whether the human chronotype is associated with ...
Young Adrienne M - - 2012
OBJECTIVE: Although several validated nutritional screening tools have been developed to "triage" inpatients for malnutrition diagnosis and intervention, there continues to be debate in the literature as to which tool/tools clinicians should use in practice. This study compared the accuracy of seven validated screening tools in older medical inpatients against ...
Sasaki Miki - - 2012
OBJECTIVE: We examined whether angiotensinogen (AGT) gene polymorphisms are associated with food preferences in young, normal female subjects. METHODS: Fifty-two young, normal female subjects (21-22 y old) were recruited. After a 12-h fast, blood samples were obtained to examine the AGT gene polymorphisms (rs699 and rs7079), angiotensin-converting enzyme (ACE) insertion ...
Cogswell Mary E - - 2012
The American Heart Association (AHA), Institute of Medicine (IOM), and US Departments of Health and Human Services and Agriculture (USDA) Dietary Guidelines for Americans all recommend that Americans limit sodium intake and choose foods that contain potassium to decrease the risk of hypertension and other adverse health outcomes. We estimated ...
Chapman Colin Daniel - - 2012
Obesity is emerging as the most significant health concern of the 21st century. Although this is attributable in part to changes in our environment-including the increased prevalence of energy-dense food-it also appears that several lifestyle factors may increase our vulnerability to this calorie-rich landscape. Epidemiologic studies have begun to show ...
Gebremariam Mekdes K - - 2012
AIMS: The aim of the study is to investigate the influence of the school food environment on the dietary behaviours of 11-year-old Norwegian children in elementary schools. METHODS: Baseline data from a school-based intervention study: the Health In Adolescents study was used. A total of 1425 11-year-old children from 35 ...
Merritt Melissa A MA Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA. - - 2013
Inconsistent results for the role of dairy food intake in relation to ovarian cancer risk may reflect the potential adverse effects of lactose, which has been hypothesized to increase gonadotropin levels, and the beneficial antiproliferative effects of calcium and vitamin D. Using data from the New England case-control study (1,909 ...
Banim Paul J R PJ Department of Medicine, University of East Anglia, Norwich, - - 2013
To investigate whether the dietary antioxidants vitamins C and E, selenium and zinc decrease the risk of developing pancreatic cancer, for the first time using 7-day food diaries, the most accurate dietary methodology in prospective work. 23,658 participants, aged 40-74 years, recruited into the EPIC-Norfolk Study completed 7-day food diaries ...
Cote-Arsenault Denise - - 2012
Background: Breastfeeding assessment in the hospital to determine adequacy of feeds remains controversial. Swallow evaluation is integral to current assessment tools, but the literature is not clear about whether the number of swallows is an accurate indicator of breast milk intake in early postpartum.Objectives: To determine the reliability and validity ...
Appelhans Bradley M BM Department of Preventive Medicine, Rush University Medical Center, 1700 W. Van Buren St., Chicago, IL 60612, USA. - - 2012
A shift from home-prepared to away-from-home and ready-to-eat foods has occurred in recent decades, which has implications for obesity and health. This study tested whether delay discounting, a facet of impulsivity reflecting sensitivity to immediate reward, is associated with the frequency of consumption and typical amount consumed of home-prepared, away-from-home, ...
Bautista C J - - 2012
Appetite is the desire to satisfy the need to consume food, felt as hunger. It is regulated by the balance of food intake and energy expenditure via signals between the brain, the digestive tract and the adipose tissue. Males and females vary in terms of eating behavior as well as ...
Deziel Nicole C - - 2013
Linzhou, China has one of the highest rates of esophageal squamous cell carcinoma in the world. Exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), may have a role in this increased risk. To better understand PAH sources, we measured PAHs in the air and food of 20 ...
Wu Yongning - - 2012
Iodine deficiency disorders were prevalent in China until the introduction of universal salt iodization in 1995. Concerns have recently arisen about possible excess iodine intake in this context. To document iodine intake and the contribution from iodized salt in China, we surveyed dietary iodine intake during China's nationally representative 2007 ...
Liu J J Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, - - 2012
The pathogenesis of obesity remains incompletely understood. Drosophila have conserved neuroendocrine and digestion systems with human and become an excellent system for studying energy homeostasis. Here, we reported a novel obesity Drosophila model, in which expression of human protein, synphilin-1 (SP1), in neurons fosters positive energy balance. To further understand ...
Kempa Daniela - - 2012
Much research has been carried out on governmental support of agri environmental measures (AEM). However, little is known about demands on and incentives from the commercial market for environmental contributions of the farmers. The factors farm structures, level of remuneration and legal framework have been thoroughly investigated. However, demands of ...
Micali Nadia N Behavioural and Brain Sciences Unit, Institute of Child Health, University College London, 4th Floor, 30 Guilford Street, London WC1N 1EH, UK. - - 2012
There is limited knowledge about dietary patterns and nutrient/food intake during pregnancy in women with lifetime eating disorders (ED). The objective of the present study was to determine patterns of food and nutrient intake in women with lifetime ED as part of an existing longitudinal population-based cohort: the Avon Longitudinal ...
Gewa Constance A - - 2012
OBJECTIVE: To examine changes in energy intake along with markers of dietary quality (animal-source energy and protein intakes) among household members in the presence of supplementary school feeding in rural Kenya. DESIGN: A 2-year, longitudinal, randomized controlled feeding intervention study. SETTING: Kyeni South Division, Embu District, Kenya. SUBJECTS: A total ...
Córdoba Caro Luis Gonzalo - - 2012
OBJECTIVES: To quantify dietary intake of secondary education students in Badajoz, Spain, evaluating food frequency use in teenagers of both sexes. MATERIAL AND METHODS: The study sample consisted of 1197 secondary education students (49.9% male and 50.1% female). After giving informed consent, they completed a self-administered food frequency questionnaire (FFQ) ...
Dutia Roxanne R Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, New York 10032, - - 2012
Proopiomelanocortin (POMC) is posttranslationally processed to several peptides including α-MSH, a primary regulator of energy balance that inhibits food intake and stimulates energy expenditure. However, another POMC-derived peptide, β-endorphin (β-EP), has been shown to stimulate food intake. In this study we examined the effects of intracerebroventricular (icv) β-EP on food ...
Phan Kongkea - - 2012
In the present study, we investigated the potential arsenic exposure of Cambodian residents from their daily food consumption. Environmental and ecological samples such as paddy soils, paddy rice (unhusked), staple rice (uncooked and cooked), fish and vegetables were collected from Kandal, Kratie and Kampong Cham provinces in the Mekong River ...
Karjalainen Anna K - - 2012
Food is contaminated by polychlorinated dibenzo-p-dioxins and furans (PCDD/F), polychlorinated biphenyls (PCB) and polybrominated diphenylethers (PBDE) worldwide. Previous data show elevated intakes in children. We determined intakes of POPs in Finnish children. Because no children-specific safe limit values exist, we used tolerable daily intakes (TDIs) set for adults by international ...
Cheng Guo - - 2012
OBJECTIVE: To determine the relative validity of a 3 d estimated food record (EFR) used to assess energy and nutrient intakes in toddlers, using a 3 d weighed food record (WDR) as the reference method. DESIGN: Parents reported the food and beverage intakes of their children using an EFR concurrently ...
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