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Kamer Barbara - - 2010
The authors evaluated mRNA TLR4 expression on neutrophils and the chosen parameters of oxidative-antioxidative balance in blood of 35 children with food allergy (17 of them with IgE-dependent allergy and 18 with IgE-independent allergy) and 15 healthy children without any allergy. The age of these children ranged from 1 to ...
Miles Michael V - - 2011
The current study evaluated 23 children (ages 2-16 years) with recurrent food intolerance and allergies for CoQ10 deficiency and mitochondrial abnormalities. Muscle biopsies were tested for CoQ10 levels, pathology, and mitochondrial respiratory chain (MRC) activities. Group 2 (age >10 years; n = 9) subjects had significantly decreased muscle CoQ10 than ...
del Giudice Michele Miraglia - - 2010
Food allergy is a frequent problem in childhood and its prevalence is increasing. In most cases food allergy is an IgE-mediated hypersensitivity response that cause skin reactions as urticaria. Subacute or chronic disorders have generally a not IgE mediated mechanism. Milk is the most common food allergen in USA and ...
Houle Christy R - - 2010
Recent estimates show that food allergies affect a substantial proportion of children in the United States and appear to have increased in prevalence. At present, management of food allergies consists of strict avoidance of the responsible allergen and an appropriate response should a reaction occur. Creating safe environments for the ...
du Toit George - - 2010
Cow's milk protein (CMP) is usually one of the first complementary foods to be introduced into the infant's diet and is commonly consumed throughout childhood as part of a balanced diet. CMP is capable of inducing a multitude of adverse reactions in children, which may involve organs like the skin, ...
Monks H - - 2010
The peak incidence of deaths from anaphylaxis associated with nut allergy occurs in teenagers and young adults. During adolescence, the management of food allergy shifts from being the responsibility of parents to that of the young person. This is a group who therefore need special attention in the clinic. This ...
Chahine Bassem G - - 2010
PURPOSE OF REVIEW: To provide an overview on the role of gut mucosal immunity in the development of tolerance to food versus allergy to food. RECENT FINDINGS: The gastrointestinal tract, through innate and specific immunologic factors, acts as a defense against ingested antigens. In addition to the mucous membrane integrity ...
Kuznar Wayne - - 2010
A lack of uniform criteria limits the determination of prevalence.
Byrne A M - - 2010
Over the last two decades, the prevalence of peanut and tree nut allergy has increased throughout the western world. Adverse reactions to these foods account for over 50% of all deaths resulting from food-related anaphylaxis. Until recently, evidence suggested that all peanut and tree nut allergy were permanent. It is ...
Waring Gillian - - 2010
The Department of Health (2006) has highlighted that food allergy is increasing in prevalence. In response, Tameside General Hospital in Greater Manchester has developed a dedicated children's allergy service. By using skin tests, followed by oral consumption of a particular food, the clinic is able to establish allergies and prevent ...
Brandtzaeg Per - - 2010
Numerous genes are involved in innate and adaptive immunity and these have been modified over millions of years. During this evolution, the mucosal immune system has developed two anti-inflammatory strategies: immune exclusion by the use of secretory antibodies to control epithelial colonization of microorganisms and to inhibit the penetration of ...
Atkins Dan - - 2010
The inadvertent transfer of food allergy from an allergic donor to an unsuspecting recipient by transfusion or organ donation is a relatively rare but intriguing event with potentially catastrophic consequences. Additionally, the development of food allergy in the recipient of a transplant from a donor who was not food allergic ...
Allen Katrina J - - 2010
Food allergy seems to represent a new spectrum of disease that has elicited significant community concern and extended waiting lists for allergists and gastroenterologists alike. The apparent rise in prevalence of IgE-mediated food allergy (and associated risk of anaphylaxis) has been postulated to result from effects of a "modern lifestyle" ...
Wang Julie - - 2010
Food allergies affect 6% of children and 3% to 4% of adults in the United States. Although several studies have examined the prevalence of food allergy, little information is available regarding the prevalence of multiple food allergies. Estimates of prevalence of people allergic to multiple foods is difficult to ascertain ...
Groetch Marion E - - 2010
To determine pediatric dietitians' self-reported proficiency, educational needs, and preferences regarding food allergy (FA) management. An Internet-based, anonymous survey was distributed to the Pediatric Nutrition Practice Group (PNPG) of the American Dietetic Association. Respondents (n = 311) were registered dietitians and members of the PNPG. Results are presented using descriptive ...
Fisher H R - - 2011
Objective To determine whether specific oral tolerance induction (SOTI) is more effective than avoidance in inducing tolerance in children aged 0-18 years who have immunoglobulin E (IgE)-mediated food allergy. Data sources MEDLINE (1950 to July 2009), EMBASE (1980 to July 2009) and all EBM Reviews: Cochrane Database of Systematic Reviews, ...
Ramakrishnan Jeevan B - - 2010
Food allergy is often an unrecognized clinical entity that has been implicated as a cause in many types of chronic inflammatory conditions. This review serves to provide an update on how food allergy plays a role in otolaryngology disorders. The incidence of food allergy has been on the rise over ...
Calhoun Karen H - - 2010
The increasing incidence of IgE-mediated food allergy has led to further study of this atopic disease. Food allergy represents a failure to attain oral tolerance marked by a pronounced Th2 versus T-regulatory cell response. The gold standard for the diagnosis of food allergy is a double-blind, placebo-controlled food challenge. Evidence ...
Chahine Bassem G - - 2010
PURPOSE OF REVIEW: To provide an overview on the role of gut mucosal immunity in the development of tolerance against allergy to food. RECENT FINDINGS: The gastrointestinal tract, through innate and specific immunologic factors, acts as a defense against ingested antigens. In addition to the mucous membrane integrity and digestion, ...
Yang Zhenyu - - 2010
BACKGROUND: Peanut allergy is relatively common among children in developed countries and may have severe outcomes, including anaphylaxis. However, few data about peanut allergy in developing countries are available. Meanwhile, formulated foods with peanuts as a major ingredient are being promoted to prevent and control malnutrition in developing countries. OBJECTIVE: ...
Panzani R - - 2010
BACKGROUND AND OBJECTIVE: Some studies hypothesize the existence of cross-reactivity between allergy to Cupressus sempervirens pollen and plant-derived foods. We aimed to assess whether this holds true. METHODS: 72 patients monosensitized to cypress pollen were investigated for food allergy to peach, apple, tomato and Juniperius oxycedrus berry. RESULTS: No patient ...
Suh Ki-Young - - 2010
The relationship between food and atopic dermatitis (AD) is complex. A common misunderstanding is that food allergies have a significant impact on the course of AD, resulting in uncontrolled attempts at elimination diets and undertreatment of the skin itself. Studies have shown that only a small portion of cutaneous reactions ...
Prescott Susan L - - 2010
PURPOSE OF REVIEW: To caution against premature proposals advocating change before epidemiological and clinical evidence warrants such a paradigm shift. RECENT FINDINGS: Until 2007, all allergy societies advocated allergen avoidance for prevention and therapy in food allergy. Since then, new evidence has prompted careful re-evaluation of the literature. In primary ...
Scurlock A M - - 2010
The gastrointestinal (GI) mucosal immune response is characterized by an intricate balance between host defense and immunoregulation. A principal element of this normal response is acquisition of oral tolerance. Aberrations in oral tolerance induction can lead to food allergy, an increasingly prevalent disorder that causes significant medical and psychosocial stressors ...
Gillman A - - 2010
International studies report marked increases in the prevalence of food allergy, along with increases in hospital admissions and emergency presentations for severe allergic reactions due to foods. The prevalence of self-reported food allergy is common, but generally exceeds that which can be verified from challenge studies, although nut allergies appear ...
Gupta Ruchi S - - 2010
Parents of food-allergic children are responsible for risk assessment and management of their child's condition. Such practices are likely informed by parental knowledge, attitudes, and beliefs of food allergy. Our objective was to characterize food allergy knowledge and perceptions among parents with food-allergic children. Parents were recruited nationally between January ...
Chafen Jennifer J Schneider - - 2010
CONTEXT: There is heightened interest in food allergies but no clear consensus exists regarding the prevalence or most effective diagnostic and management approaches to food allergies. OBJECTIVE: To perform a systematic review of the available evidence on the prevalence, diagnosis, management, and prevention of food allergies. DATA SOURCES: Electronic searches ...
Ben-Shoshan Moshe - - 2010
Recent studies suggest an increased prevalence of food-induced allergy and an increased incidence of food-related anaphylaxis. However, prevalence estimates of food allergies vary considerably between studies. To determine the prevalence of peanut, tree nut, fish, shellfish, and sesame allergy in Canada. Using comparable methodology to Sicherer et al in the ...
Kunisawa Jun - - 2010
The gastrointestinal immune system is a major component of the mucosal barrier, which maintains an immunologic homeostasis between the host and the harsh environment of the gut. This homeostasis is achieved by immunologic quiescence, and its dysregulation is thought to result from the development of immune diseases such as food ...
Railey Mary Dell - - 2010
Food allergy is a life-changing and potentially life-threatening diagnosis, affecting approximately 6% of children and 4% of adults in the United States. A small number of foods account for the vast majority of food allergies, and the reactions after ingestion of a food to which a person is allergic are ...
Kamdar Toral - - 2010
Food allergies are caused by immune responses to food proteins and represent a breakdown of oral tolerance. They can range from mild pruritus to life-threatening anaphylaxis. The only current consensus for treatment is food avoidance, which is fraught with compliance issues. For this reason, there has been recent interest in ...
Carlisle Suzanna K SK University of Arkansas for Medical Sciences, - - 2010
Food allergy is increasing in school-age children. School nurses are a primary health care resource for children with food allergy and must be prepared to manage allergen avoidance and respond in the event of an allergic reaction. An anonymous survey was administered to school nurses attending their association meetings to ...
Galli E - - 2010
Recent studies have indicated that Toll-like receptor polymorphisms or their impaired signalling, specifically TLR-2 and TLR-4, were correlated with a higher risk for allergy. The purpose of this study is to evaluate the associations of TRL-2 and TRL-4 single nucleotide polymorphisms (SNP) and atopic traits in a cohort of 159 ...
Vassallo Milo F - - 2010
The prevalence of food allergy is rising, and etiologic factors remain uncertain. Evidence implicates a role for vitamin D in the development of atopic diseases. Based on seasonal patterns of UV-B exposure (and consequent vitamin D status), we hypothesized that patients with food allergy are more often born in fall ...
Madsen Charlotte B - - 2010
We have reached a point where it is difficult to improve food allergy risk management without an agreement on levels of acceptable risk. This paper presents and discusses the perspectives of the different stakeholders (allergic consumers, health professionals, public authorities and the food industry) on acceptable risk in food allergy. ...
Noh Geunwoong - - 2010
Food allergy plays an important role in atopic dermatitis (AD). Adequate predictors and guidelines for when dietary manipulation is indicated for AD are needed. The clinical significance of eosinophilia as a predictor for food allergy of late eczematous reactions in AD was investigated. Three hundred three patients with AD were ...
Kurihara Kazuyuki - - 2010
Although the current standard care for patients with food allergy is based on avoidance of the trigger foods with hope of possible gain of tolerance, increasing number of studies have shown that oral immunotherapy is a promising approach. Understanding the transcutaneous sensitization and oral immune tolerance to food antigens has ...
Cummings A J - - 2010
Food allergy affects 6% of children but there is no cure, and strict avoidance of index allergens along with immediate access to rescue medication is the current best management. With specialist care, morbidity from food allergy in children is generally low, and mortality is very rare. However, there is strong ...
Zuercher A W - - 2010
BACKGROUND: The immune system may be modulated with nutrition to prevent the development or to treat the symptoms of allergy. Among other foods, consumption of apples has been linked to reduced incidence of atopic dermatitis and respiratory allergy. OBJECTIVE: We evaluated the efficacy and mechanisms of a polyphenol-enriched apple extract ...
Diesner Susanne C SC Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, - - 2011
Epidemiologic studies report an increase in food allergies in industrialized countries, but mainly focus on children and young adults. This leads to the impression that food allergies do not occur in the older population. However, age-related changes dramatically affect both the innate as well as the adaptive immune system - ...
Ramagopalan Sreeram V - - 2010
Autoimmune mechanisms are thought to have a major role in the pathogenesis of multiple sclerosis (MS) and vitamin D is hypothesised to contribute to disease susceptibility. Cow's milk allergy (CMA) is a common childhood allergy arising from an immune system imbalance and can also lead to vitamin D deficiency due ...
Hong Sandra - - 2010
Food allergies have increased in prevalence significantly in the past decade and so, apparently, has eosinophilic esophagitis. Although the cause of eosinophilic esophagitis is unknown, allergic responses including food allergies have been implicated. This article reviews both conditions, focusing on how to detect and manage them.
Cuesta-Herranz Javier - - 2010
BACKGROUND: A considerable number of pollen-allergic patients develops allergy to plant foods, which has been attributed to cross-reactivity between food and pollen allergens. The aim of this study was to analyze the differences among pollen-allergic patients with and without plant food allergy. METHODS: Eight hundred and six patients were recruited ...
Gupta Ruchi S - - 2010
OBJECTIVE: To provide insight into food allergy knowledge and perceptions among pediatricians and family physicians in the United States. METHODS: A national sample of pediatricians and family physicians was recruited between April and July 2008 to complete the validated, Web-based Chicago Food Allergy Research Survey for Primary Care Physicians. Findings ...
Bird J Andrew - - 2009
Food allergy and asthma commonly co-exist in the same patient with approximately one-third of children with food allergy having asthma. When both atopic conditions are present a food allergic patient is placed at greater risk of having a fatal reaction from food allergen exposure. For this reason asthma should be ...
Hong Xiumei - - 2009
Food allergy, a growing clinical and public health problem in the United States and worldwide, is likely determined by multiple environmental and genetic factors. The purpose of this review is to summarize recent advances in food allergy genetic research. There is compelling evidence that genetic factors may play a role ...
Mullins Raymond J - - 2010
There is little information on the regional distribution of food allergy in Australia. We examined the influence of latitude (a marker of sunlight/vitamin D status) on food allergy, as measured by 2007 infant hypoallergenic formula (IHF) prescription rates in children ages 0-2 yrs. Data were compiled from the 52 statistical ...
Branum Amy M - - 2009
OBJECTIVES: The goals were to estimate the prevalence of food allergy and to describe trends in food allergy prevalence and health care use among US children. METHODS: A cross-sectional survey of data on food allergy among children <18 years of age, as reported in the 1997-2007 National Health Interview Survey, ...
Wong G W K - - 2010
BACKGROUND: Very little is known regarding the global variations in the prevalence of food allergies. The EuroPrevall-INCO project has been developed to evaluate the prevalence of food allergies in China, India and Russia using the standardized methodology of the EuroPrevall protocol used for studies in the European Union. The epidemiological ...
MacDonald Thomas T - - 2009
PURPOSE OF REVIEW: Food allergies are common in children, although rare in adults. They can be life threatening via anaphylaxis, especially to peanut, and cause distress to children and parents because of the disease itself, and then through the difficulty of pursuing a strict elimination diet. In parents/carers and adults, ...
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