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Results 351 - 400 of 617
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Sandström R - - 1990
This investigation has addressed the question whether food and water intake, motor activity and tumour growth are influenced by indomethacin in experimental cancer. Growing rats implanted with a methylcholanthrene-induced sarcoma were studied in metabolic cages connected to a computer. Food intake, water consumption and motor activity were continuously recorded over ...
Fujimura A - - 1990
The present study was undertaken to examine whether influences of furosemide on biochemical parameters vary with its time of administration in Wistar rats. Rats were maintained under conditions of light (0700-1900 hrs) and dark (1900-0700 hrs). Furosemide (30 mg/kg) or vehicle (5% glucose) was given orally at 1000 hrs (day ...
Koopmans H S - - 1990
Parabiotic pairs of inbred Lewis rats had two different types of crossed intestinal surgery performed. In the one-way surgery, food was lost from the duodenum of one rat in a pair into a 30 cm segment of upper small intestine of its partner. The unabsorbed intestinal chyme returned to the ...
Swiergiel A H - - 1990
The serotonin antagonist pizotifen (BC-105) is prescribed as an appetite and weight enhancer (Mosegor--Wander, also commercialized under brand names Sanmigran or Sandomigran--Sandoz, Switzerland) for anorectic and convalescent humans. There has been, however, difficulty in demonstrating any orexigenic effect of pizotifen in laboratory animals. In the present report, the influence of ...
Pettersson L G - - 1990
The role of defined descending pathways in the control of forelimb movements in cats was investigated in behavioural experiments. The movements studied were "target-reaching" (i.e. the movement used to reach for food) and "food-taking" (i.e. the movement used for grasping a piece of food and for bringing it to the ...
Phelps M T - - 1989
We studied central-place foraging in rats (Rattus norvegicus) by placing food items that varied in size and weight at the ends of a 4-arm radial maze. In Experiments 1-3, rats increasingly tended to carry food to the center of the maze as the size of those items increased. Very large ...
Ruis J F - - 1989
Rats subjected to Eat-Fast (EF) cycles show food-anticipatory rhythms independent from the suprachiasmatic nuclei (SCN). These rhythms do not persist during subsequent ad lib feeding (EE). There are indications for a recovery of rhythmicity during fasting (FF) using a 'memory' paradigm in which FF sessions are alternated with EE. In ...
Tomoyasu N - - 1989
The role of palatability, novelty, and food aversion in determining changes of food choice after ablation of the area postrema and caudal-medial aspect of the nucleus of the solitary tract (AP/cmNTS) is examined through a series of studies utilizing 24-h, two-food choice tests. On test days, the food that the ...
Thombre D P - - 1989
Central effects of insulin on 20 min. food intake were studied in rats. Insulin administration in the lateral ventricular cerebrospinal fluid (CSF) did not alter food intake in the intact or lesioned ventromedial hypothalamus (VMH) rats. Whereas, after insulin injection in VMH there was a decrease in food intake. In ...
Steketee J D - - 1989
It has been reported that depletion of forebrain norepinephrine via 6-hydroxydopamine infusion into the dorsal bundle decreases the rat's ability to selectively attend to relevant stimuli and thus increases the rat's responsiveness to novelty. In this study we measured 6-hydroxydopamine lesion effects on 1) selective attention via the nonreversal shift ...
Stephan F K - - 1989
Rats with lesions of the suprachiasmatic nuclei (SCN) and intact rats were maintained on restricted feeding with the duration of food access ranging from 4 to 12 hr. All rats with SCN lesions displayed at least some anticipatory activity (AA) at all food access durations. The amount of AA diminished ...
Gentle M J - - 1989
After 19 weeks on a mash diet nine of the 10 birds exhibited from two to 19 oral lesions. The majority of these lesions involved the total erosion of the buccal epidermis giving a total area of exposed dermis of 0.6 to 94.5 mm(2). This was accompanied by a significant ...
Racotta R - - 1989
Monosodium glutamate (MSG) was recently reported to increase feeding in ad lib. fed rats [Reddy et al.(4)]. In the present study the responses of male and female adult rats to subcutaneous (SC) administration of MSG were compared. In female rats MSG 3 g/kg did not significantly affect food or water ...
King B M - - 1989
Radio-frequency and anodal electrolytic lesions of the paraventricular nucleus (PVN) were found to produce equal and dramatic increases in body weight in female rats. Neither of the groups with lesions had significantly elevated plasma insulin levels during a period of food restriction, but individual values varied greatly. Both groups displayed ...
Whishaw I Q - - 1989
The study demonstrates novel features of rat hoarding, patterns of recovery from medial frontal cortex damage that are behaviorally dependent, and new methodology for studying hoarding. Rats were placed in a covered cage connected to an alley at the end of which were food pellets varying in size between 20 ...
Refinetti R - - 1989
The thermopreferendum of male hooded rats was studied in a temporal thermal gradient. The preferred ambient temperature was found to be approximately 19 degrees C. In addition to the thermopreferendum, three other physiological functions (resting body temperature, daily food intake, and daily ambulatory activity) were each measured in eight rats ...
Agarwal V - - 1989
Isoproteinous diets containing 1% cholesterol and 10% fibre derived from plant foods namely, peepalbanti (Ficus religiosa), barbanti (Ficus bengalensis), gullar (Ficus glomerata), teent (Capparis decidua) and khejri beans (Prsopsis cineria) or pure cellulose, were fed to rats for 40 days. Effect of incorporation of these whole plant parts on feed ...
Morales A - - 1989
Rats with polydipsia induced by electrolytic mammillary lesions show a normal daily rhythmicity of water intake compared with sham lesioned animals, when kept in a 12:12 hours light-dark cycle of illumination. Water is mainly consumed during the dark phase (approximately 80-90% of the total amount). On the other hand, rats ...
Honma S - - 1989
Rats were lesioned in the SCN and treated with methamphetamine dissolved in drinking water. A robust rhythm appeared in spontaneous locomotor activity which was not affected by blinding. Periodic food restriction (RF) of a 24 hr period was imposed on SCN lesioned rats with free-access to food for 4 or ...
Cabanac M - - 1989
An alimentary/thermic conflict of motivation was used to explore the effects of very low doses of dexfenfluramine (dFF), an anorectic serotoninergic agonist, on the parameters of food motivation, drive and incentive (or palatability). Six rats trained to feed 2 hr/day, were given the possibility to feed on chow in a ...
Weaver D R - - 1989
Destruction of the maternal suprachiasmatic nuclei (SCN) early in gestation disrupts maternal communication of time-of-day information to the rat fetus. In the present study, we demonstrated that periodic feeding (food cue) to SCN-lesioned pregnant rats entrains the fetal biological clock. The phase of the drinking behavior rhythm was examined in ...
Bernardis L L - - 1989
Following a brief period of ad lib (AL) feeding, 45-day-old male Sprague-Dawley rats were either fed AL or food-restricted (REST) for 21 days to 50% of the intake of the AL rats. At this time, some AL and some REST rats received electrolytic lesions in the dorsomedial hypothalamic nuclei (DMNL), ...
Gerardo-Gettens T - - 1989
Increases in serum estrogen inhibit food intake. Conversely, progesterone stimulates food intake, probably via its antiestrogenic action. We have reported that elevated serum prolactin also stimulates food intake in female rats. It is unclear whether this effect is mediated through elevated levels of progesterone. The present study investigated the effects ...
Edwards G L - - 1989
Lesions of the area postrema and adjacent nucleus of the solitary tract (AP lesions) cause rats to consume increased amounts of palatable food in short duration tests. Because the lateral parabrachial nucleus (lPBN) receives a prominent afferent projection from the AP and adjacent nucleus of the solitary tract, it is ...
Demestre I - - 1989
The reference parameters for 10- and 19-week old CFY (remote Sprague-Dawley) rats fed powdered feed have been studied: growth curves, food consumption, ophthalmoscopy, results of urinalyses and hematological and biochemical assays, and absolute and relative organ weights. Detailed information is given of instrumentation and methods employed, of the animals, strain ...
Whishaw I Q - - 1989
Rats were trained to reach for food pellets, which varied in size from 20 to 300 mg, from one of 21 locations on a shelf located just outside a test cage. After a barrier was lifted, giving access to a food pellet, latency to contact the food was timed, number ...
Dawson R R - - 1989
Studies were conducted to examine deficits in food intake regulation in MSG-treated rats that result from known or suspected damage to neurotransmitter systems involved in feeding. Male rats were injected with either MSG (4 mg/g) or sodium chloride on postnatal days 2 and 4 (MSG-Lo) or postnatal days 2, 4, ...
Swiergiel A H - - 1989
Rats were trained to feed 2 h daily. Each rat was presented during three 10-day-long alimentary periods with each of the following diets: control (C), low calorie (L), and high calorie (H). The food was placed at an ambient temperature of -15 degrees C at 16 m from a warm ...
Ito M - - 1989
We studied the influence of food-intake during a fixed period on hydrocortisone-induced relapse of acetic acid ulcers in rats. The ulcer index, the defective area of the ulcerated region and the exposure index for the ulcer floor in the food-intake-time limited group markedly increased as compared to those in the ...
Sorvari R - - 1989
Young Osborne-Mendel rats were given different diets ad libitum for 6 weeks. Food was either a purified powder with sucrose (15%) or commercial pellets, and drink was either distilled water or a sugar-containing (6%) sport-drink with or without added fluoride (F), magnesium (Mg) or both. Despite differences in the energy ...
Carpenter K J - - 1989
Seventeen test foods were each analyzed by four methods. Total lysine was measured by conventional amino acid analysis. Reactive lysine was measured with either fluorodinitrobenzene, o-phthalaldehyde or a differential dye-binding procedure. The results were then compared with another group's results from rat growth assays of the same samples for availably ...
Noskovic P - - 1989
The ribonucleic acid (RNA) and protein content of the ventromedial hypothalamic nuclei (VMH), the lateral hypothalamic areas (LHA) and the cortex (C) of adult male Wistar rats followed free access to food and water were determined at 6-hour intervals (at 6.00, 12.00, 18.00 and 24.00 h); the RNA and protein ...
Kalsbeek A - - 1988
In order to examine the effect of neonatal depletion of the dopaminergic mesocortical projection on the development of prefrontal cortex-mediated behaviors, male and female adult rats with neonatally applied thermal lesions of the dopaminergic A10 cell group in the ventral tegmental area were studied in a food-hoarding situation. Control male ...
Leshem M - - 1988
In previous work (Leshem, M., Boggan, B., and Epstein, A.N. (1988). The ontogeny of drinking evoked by activation of brain angiotensin in the rat pup. Dev. Psychobiol. Vol.21, pp. 63-75) we showed that thirst elicited by activation of the brain's renin-angiotensin system in the suckling becomes specific to water after ...
Timberlake W - - 1988
The primary goal of this experiment was to determine whether the addition of an operant requirement for access to a less costly (continuous reinforcement) patch of future food increased the time horizon over which that future patch decreased intake in a currently available depleting (progressive-ratio) patch. Three groups of 4 ...
Ramos J M - - 1988
This study was based on several recent anatomical studies suggesting that the superior salivatory nucleus is located within the area parvocellularis of the brainstem reticular formation. The aforementioned zone was lesioned in order to observe the alterations produced in salivary secretion. Electrolytic lesion of the area parvocellularis was followed by ...
Kant G J GJ Department of Medical Neurosciences, Walter Reed Army Institute of Research, Washington, DC - - 1988
The purpose of these experiments was to evaluate the utility of a water maze for testing performance in nonfood-restricted rats. Water maze performance was compared to performance in a food-rewarded (food) maze. Separate groups of rats were given single daily trials of 34 days in one of two mazes. The ...
Erlanson-Albertsson C - - 1988
Pancreatic pro-colipase activation peptide, a pentapeptide with the sequence VPDPR was found to significantly suppress food intake of 20 h fasted Sprague-Dawley rats in a dose-dependent way. A rat treated with pro-colipase-enriched pellets for 26 days showed decreased daily food intake and retarded growth, which were restored during a following ...
Erlanson-Albertsson C - - 1988
Pancreatic procolipase is a cofactor for lipase and necessary for optimal fat digestion in the intestine during a meal. It is activated by trypsin in the intestine during release of an activation peptide, with the sequence Val-Pro-Asp-Pro-Arg in rat. This peptide, in the following termed VPDPR, was found to decrease ...
Contreras S - - 1988
The effect of pyrazole (35 or 70 mg/kg IP) on the voluntary consumption of ethanol, water and solid food was studied in UChA (genetically low ethanol consumer) and UChB (genetically high ethanol consumer) rats of both sexes, under a free choice of 10% v/v ethanol solution, distilled water and solid ...
Querido D - - 1988
An accurate and reproducible technique was employed for measurement of water content (RBCH2O) and potassium concentration (RBCK) in rat erythrocytes post mortem. Coefficients of variation for determination of RBCH2O and RBCK, as estimated from the results of duplicate analyses (n = 36), were 1.21% and 1.17%, respectively. Erythrocyte water content ...
Suzuki T - - 1988
The establishment of, and sex differences in, physical dependence on methaqualone (MQ) in rats were studied by the drug-admixed food (DAF) method. Female and male rats were treated with MQ-admixed food on the same schedule of gradually increasing doses (0.5 and 1 to 6 mg of methaqualone/g of food). Only ...
Cox J E - - 1988
We investigated the anatomical basis of paraventricular (PVN) and ventromedial (VMH) hypothalamic hyperphagia. Asymmetrical electrolytic lesions, damaging the VMH and PVN contralaterally, produced significant hyperphagia and weight gains (mean = 257.2 g) almost three times those of controls (89.8 g) during 56 postsurgical days. Weight gain in these rats was ...
Whishaw I Q - - 1988
Developments of a procedure to study two movements, food wrenching (stealing food from a conspecific) and dodging (escaping with food from a conspecific), used in the competition for food by rats is described. These include, (A) procedures for adaptation, (B) procedures for filming and scoring, and (C) procedures for measuring ...
Rattan A K - - 1988
Injections into third ventricle of brain of either 4 m Molar or 8 m Molar of GABA were given to intact and ovariectomized female rats to evaluate the effects of these dosages on body weight, food intake, water intake and blood glucose levels. Statistically significant reduction in food and water ...
Bowden C R - - 1988
Histidyl-proline diketopiperazine [cyclo(His-Pro)], a metabolite of thyrotropin releasing hormone (TRH), has been reported to decrease food intake of rats in a variety of feeding models following intracerebroventricular (ICV) injection. We have re-evaluated the anorectic effects of cyclo(His-Pro) on food deprivation-induced and spontaneous feeding. When injected ICV at the end of ...
Whishaw I Q - - 1988
Sensorimotor behavior in unilateral decorticate and unilateral dopamine-depleted rats was studied in a naturally occurring social interaction in which rats compete for food with relatively stereotyped species-typical responses. In the interaction a "robber" attempts to wrest food from a feeding "victim," which in turn protects the food by making rapid ...
Cornblath D R - - 1988
Animals with experimentally induced neuropathies frequently fail to gain weight normally and appear poorly nourished. To determine whether or not malnutrition alone contributes to peripheral nerve dysfunction in these disorders, we subjected healthy 40-day-old rats to three grades of food restriction. After 4 weeks, food-restricted rats weighed 203 +/- 5 ...
Lafont J - - 1988
It is now generally admitted that phytohemagglutinin (PHA) constitutes the main factor responsible for the dietary toxicity of raw kidney beans. In the growing rat, an impairment of growth is the unique expression of a malnutrition syndrome. The aim of this work was to precise to what extent the intestinal ...
McGowan M K - - 1988
Electrolytic lesions in the MPO of rats had no significant effects on ad lib food and water intake, but impaired the drinking response to 1 M NaCl. Large MPO lesions also produced a persistent increase in plasma osmolality. In Experiment 2, we depleted neurons from the MPO of rats by ...
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