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Results 301 - 350 of 660
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Martel P P Département de Physiologie Humaine et Expérimentale, Faculté de Médecine/Université de Bourgogne, - - 1996
The mesolimbic dopaminergic system (MDS) has been shown to be implicated in feeding behaviors. The present experiment was conducted to examine the effects of the sensory properties of food ingested on MDS activity. Microdialysis coupled to high-performance liquid chromatography with electrochemical detection was employed to measure the extracellular levels of ...
Wang J F - - 1995
Energy expenditure was measured in one-way crossed-intestine rats by use of indirect calorimetry to examine the role of energy metabolism in body weight control. The intestinal surgery was done according to Koopmans (Brain Res. Bull. 14: 595-603, 1985). The food-losing rats increased daily food intake from 70.8 to 126.3 g/day, ...
Sidlo J - - 1995
BACKGROUND: Rats have an extraordinary expressive circadian organization and prefer the dark as the optimal condition of its life environment. During darkness, the rhythm of its several parameters reaches the acrophase. MAIN PURPOSE: The aim was to establish the differences in the level of food-intake of laboratory rats of the ...
Ikeda H - - 1995
Antiobesity and antidiabetic actions of the alpha-glucosidase inhibitor AO-128 were examined using genetically obese-diabetic rats, Wistar fatty. Ten-week-old, male fatty rats were kept on CE-2 diet containing 10 or 25 ppm of AO-128 for 4 weeks. The average drug intake was calculated to be 0.74 or 1.78 mg/kg/day from the ...
Mühlbauer R C - - 1995
Using the urinary excretion of [3H]-tetracycline from prelabeled rats to monitor bone resorption, we have previously shown that food intake is associated with a rapid and large increase in bone resorption. This increase is blunted when the daily intake is fractionated into 4 portions instead of being given at once. ...
Flynn F W - - 1995
Hypertonic saline (HS) administered intraperitoneally reduced the intake of sucrose solution infused intraorally in tube-fed decerebrate rats, as it did in control animals. Similarly, either intraperitoneal or intravenous HS markedly decreased the intake of laboratory chow by neurologically intact control rats. These observations complement recent findings that lesions of putative ...
Helder R - - 1995
The social behavior of outbred Long-Evans (LE) and Wistar (WI) rats was compared in a situation where access to food was particularly difficult (clearing an aquatic barrier, plus the necessity of carrying the food back to the home cage). In groups of either six WI or LE rats, only about ...
Fisler J S - - 1995
We have examined the effect of peripheral 3-hydroxybutyrate injections on food intake and the contribution of the vagus nerve in the resistance to dietary fat-induced obesity in a rodent model. S 5B/Pl rats, which are resistant to dietary-fat induced obesity, and Osborne-Mendel rats, which are sensitive, were adapted to reverse ...
Porter J R JR Department of Medicine, LSU Medical Center, New Orleans 70112, - - 1995
Dehydroepiandrosterone (DHEA) decreases body weight and food intake of the obese Zucker rat, a model of youth-onset obesity associated with hyperphagia. The effects of discontinuing DHEA treatment on these parameters, however, has not been investigated. This question was studied in rats that had been maintained on DHEA-supplemented (0.0%, 0.06%, 0.15%, ...
Hamm R J - - 1995
To investigate the function of the amygdala following traumatic brain injury (TBI), rats were tested on a gustatory neophobia task that is sensitive to amygdala and hippocampal damage. Rats were either injured at a moderate level of fluid percussion injury (2.1 atm) or surgically prepared but not injured (sham-injury). Seven ...
Santana P - - 1995
Corticosteroids stimulate and insulin inhibits energy acquisition (food intake); conversely, corticosteroids inhibit and insulin stimulates energy storage (body weight gain). Thus, together these hormones mediate long-term energy balance. This study tested whether the stimulatory action of corticosteroids on food intake was mediated by association with high affinity mineralocorticoid receptors (MRs) ...
Harris R B - - 1995
When one member of a parabiosed pair of rats is overfed, its ad libitum-fed partner loses body fat in the absence of a statistically significant decrease in food intake. Three experiments investigated the relationships between food intake, metabolism, and body composition in this model. In vivo measurement of lipogenesis confirmed ...
Carter C G - - 1995
This study investigates whether tissue free amino acid (FAA) pools in rainbow trout,Oncorhynchus mykiss (Walbaum), are altered following feeding and the relationships between the amount of food consumed and the FAA pool size. Trout were starved for 7 days to provide baseline data and then refed on day 8. Individual ...
Munch I C - - 1995
Resting metabolic rate was measured in rats receiving single or double food portions every day or every other day, adding up to the same total food intakes. Starving rats were also measured. At two different total food intakes, there were no differences between the rats that were fed a meal ...
Colomb V - - 1995
Experimental sepsis in rats induces a restriction in spontaneous food intake and a drop in liver glutathione, cytochrome P-450 (P-450) and aminopyrine demethylase (AD) activity. The present study was designed to assess the effects of antibiotics alone or when combined with food deprivation on these variables. Eighty-nine male Sprague-Dawley rats ...
Wang J F - - 1995
The involvement of central and peripheral catecholamines and serotonin (5-HT) in regulation of feeding and energy metabolism was examined in one-way crossed intestine rats that show large and sustained changes in daily food intake. Five to six weeks after the crossed-intestinal surgery, catecholamines and indoleamines in dissected major brain regions ...
Balleine B - - 1994
In a series of studies, we assessed the effects of ibotenic acid lesions of the nucleus accumbens on instrumental performance in hungry rats. Although these lesions were found to generally impair lever press performance for both food pellets and a sucrose solution, they did not affect sensitivity to changes in ...
Makino T - - 1994
Morphologic changes in the hepatocytes of tumour-bearing rats at the pre-cachectic and cachectic stages were studied by electron microscopy and were quantitatively analysed by a morphometric method. Ten male F-344 rats, subcutaneously inoculated with methylcholanthrene-induced sarcoma cells (TBR) were compared with ten pair-fed controls (CTR). There was no significant difference ...
Dringenberg H C - - 1994
The effects of the putative anxiolytic agent buspirone on food-handling behavior of laboratory rats were investigated. Rats trained to travel from a covered shelter to a food source were provided with food pellets of six sizes. Smaller pellets were eaten at the exposed food source, whereas larger pellets were carried ...
Stefurak T L - - 1994
The tegmental pedunculopontine nucleus (TPP) of the brainstem has been identified as a critical substrate for both opiate and food reward in nondeprived rats. In this study of rats, TPP lesions blocked saccharin-conditioned place preferences, in both the presence and the absence of water deprivation. TPP lesions also attenuated the ...
Thombre D P - - 1994
Inbred albino rats were exposed to different feeding schedules before and after caudate nucleus lesions. The animals show adaptation to the new patterns of food deprivation even after caudate nucleus lesions. However, the lesioned animals are not able to elevate their food intake or body weight to the prelesion levels. ...
Salamone J D - - 1994
This experiment was undertaken to investigate the role of nucleus accumbens dopamine (DA) in instrumental and consummatory responses for food. In vivo microdialysis methods were used to study DA release and metabolism in the nucleus accumbens of behaving rats. Four behavioral conditions were used: performance on a fixed ratio 5 ...
Fleming A S - - 1994
The researchers examined the number of cells showing Fos-like immunoreactivity (Fos-lir) in the brains of hormonally primed parturient rat dams immediately following their first behavioral interactions with pups. Groups were exposed to newborn pups (pup), adult conspecifics (social), or a new food (food), or they were left alone in cages ...
Anderson G H - - 1994
This study examined the effects of selected groups of essential amino acids (EAAs), given by gavage, on short-term food and water intake. Amino acid groups were selected on the basis of their common physiologic functions in relation to current hypotheses on the role of amino acids in food intake control, ...
Bane A J - - 1994
Previously, we have shown that patterns of food selection are altered by pregnancy and lactation in rats. Reproductive animals increase total food intake during gestation and lactation, and select more carbohydrate and protein during lactation than virginal controls. In other self-selection studies, female rats administered cocaine compensate for decreases in ...
Kenney N J - - 1994
Rats with lesions of the area postrema (APX rats) avoid foods ingested on a regular basis during the period of severe hypophagia immediately following surgery (Tomoyasu & Kenney, 1989). The present work determined whether APX rats would also avoid foods to which they are exposed only after they have recovered ...
Deviterne D - - 1994
Behavioral profiles of male rats were defined in nine intralitter groups of six individuals at various stages of their development: (a) at pup stage in individual situations (uncomfortable positions) and social situations (removal away from the mother), and (b) at adult stage in a difficult food supply social situation (complete ...
Doi T - - 1994
To clarify involvement of hypothalamic neuronal histamine in feeding circadian rhythm, we analyzed rat behavioral patterns using chemical probes which affect endogenous histaminergic activity. Sustained infusion of alpha-fluoromethylhistidine (FMH), a specific suicide inhibitor of a histamine-synthesizing enzyme, into the rat third cerebral ventricle disrupted light-dark cycles of feeding, drinking, and ...
Martí O - - 1994
The effect of exposure to chronic intermittent stressors of differing intensities [handling, restraint, and immobilization (IMO)] and daily duration (15, 60, and 240 min of IMO) on changes in food intake was studied in adult male rats. Whereas handling did not caused anorexia, restraint slightly reduced food intake and IMO ...
Whishaw I Q - - 1994
Adult rats depleted bilaterally of dopamine in infancy display a profound impairment in skilled forelimb use in reaching for food. This impairment was investigated using end-point measures of reaching success, movement analysis, and kinematic measures. The rats made few successful reaches in either an easy or a difficult reaching test. ...
Galef B G BG - - 1994
Using techniques developed by Hall (1975) and modified by Diaz (1991), we maintained rat pups in total social isolation from the time they were 2 or 3 days of age until they were 42 days old. We found that rat pups reared in social isolation exhibited susceptibility to social enhancement ...
Gleason T C - - 1994
A landmark discrimination task similar to that previously used with monkeys was adapted to measure allocentric spatial ability in rats. Rats were trained to approach one of two food wells, placed 36 cm apart, based on the proximity of the landmark. During initial training, the landmark was adjacent to the ...
Whishaw I Q - - 1994
Although it is well known that rats can use one limb to reach for and retrieve food, the way that the paw and digits are used to grasp the food has not been described. Using results obtained from a high speed videorecording procedure, the present study describes how small and ...
Grimsley D L - - 1994
Sodium-deficient rats will seek out NaCl in food or solution and regulate their salt need. The question of this study is the extent to which salt-seeking behavior can be modified by long-term exposure to a high NaCl diet. Four female rats were divided into two groups: (1) animals that were ...
Del Prete E - - 1993
The aim of the present study was to investigate the influence of age and hepatic branch vagotomy on the night/day distribution of food intake in male rats. Food intake of young (age: 2 months) and aged (age: 13.5 months) hepatic branch vagotomized (HBV) and sham-vagotomized (SV) rats was measured at ...
Manabe S - - 1993
The effects of phenylacetate (PA) on fetal brain growth were examined in pregnant rats receiving a 20% casein diet with 1.0, 1.5, 2.0 or 2.5% PA. Control rats were fed the 20% casein diet ad libitum or restricted to daily consumption of 9 and 6 g. In experimental groups of ...
Meguid M M - - 1993
To determine whether brain glycogen concentrations change during parenteral nutrition, Fischer 344 rats with jugular vein catheters received 0.9 N saline or parenteral nutrition providing 100% of daily calories (PN-100). Rats were killed after 4 days of PN-100 and serially after PN-100 was stopped. Food intake decreased during PN-100 to ...
Westwood N N - - 1993
The aim of the study was to determine the activity of monoamine oxidase (MAO) and the contributions of the A and B forms of MAO to the metabolism of norepinephrine (NE) in isolated perfused lungs of the rat. Preliminary experiments to investigate the MAO-A and MAO-B selective inhibitors, Ro41-1049 and ...
Murphy H M - - 1993
Vasopressin-containing, Long-Evans (LE) rats and vasopressin-deficient, Brattleboro (DI) rats were monitored for activity and core body temperature via telemetry. Rats were exposed to a 12-12 light-dark cycle and allowed to habituate with ad lib access to food and water. The habituation period was followed by an experimental period of 23 ...
Velasco Plaza A - - 1993
The light/dark (L/D) rhythms of food and water intake and urine output were studied in normal and diabetic rats for 7 consecutive days at 4-h intervals. The control rats showed the highest values of these parameters during the dark phase (83.68% food, 68.71% water, and 67.44% urine). The diabetic rats ...
Giner M - - 1993
The effects of a continuous intragastric (via a gastrostomy) and intravenous (via an indwelling jugular catheter) infusion of 3% ethanol at 3 ml/h on food intake was examined in rats randomly assigned to a two period crossover study. The 3% ethanol solution provided 19 kcal/day, which was equivalent to about ...
Whishaw I Q - - 1993
Although it was once thought that the corticospinal (pyramidal) tract was the main substrate of voluntary movement, the extent to which it is involved in the control of proximal vs. distal musculature, independent finger movements, and movements characteristic of different species of animals now is unclear. The objective of this ...
Whishaw I Q - - 1993
Rats transport food from exposed areas to covered areas where they eat it or leave it. Although there is evidence that limbic structures play a role in food transport, their role is controversial. Here it was found that although many rats with large hippocampal, septal/diagonal band of Broca or dorsomedial ...
Burden V R - - 1993
Activity-based anorexia is characterized by suppressed food intake and excessive physical activity. These behaviors are typical of persons with anorexia nervosa. Activity of the hypothalamic-pituitary-adrenal axis is known to be elevated in anorexia nervosa. We investigated the status of this axis in activity-based anorexia. Meal fed-control (MFC) and meal fed-wheel ...
Amin R J - - 1993
Rats exposed to lead (lead acetate) in doses of 0.2 and 0.5 mg/ml in drinking water for a period of 90 days showed mild to moderate changes in food consumption compared to control group. Drug interactions in lead exposed rats with metoclopramide, atropine sulphate, propranolol, cyproheptadine and mepyramine maleate when ...
Baskin D G - - 1993
Three groups of ovariectomized rats were treated for 6 days: 1) estradiol benzoate (100 micrograms/kg) (SC) and fed ad lib; 2) vehicle-injected controls fed the same amount of food as eaten by estradiol-treated rats; 3) vehicle-injected, free-feeding controls. Specific binding of insulin to liver and hypothalamus slices was measured by ...
Kidwai A M - - 1993
Hunger and satiety are complex interplay of several factors in human and animal species. Reduced food intake has also been observed under various pathological conditions. Earlier, we have been able to isolate an endogenous glycoprotein from erythrocyte membranes, which causes anorexia in rats. In the present study, a similar anorexigenic ...
Gnacinska G - - 1993
The hormonal mechanism involved in stress-induced dysregulation of feeding behaviour is not known. In this study anterior pituitary hormones: GH and prolactin/PRL were analyzed, immediately and 60 min. after 1 hr immobilization stress, in rats with enhanced or with diminished food intake. The results show, in rats with diminished food ...
Harris G D - - 1993
To determine if osmoprotective molecules accumulate in the brain during severe DKA with extreme (DKA-E) and moderate (DKA-M) dehydration, Fischer 344 rats (250-350g) were given STZ 45 mg/kg (i.p.) and allowed food and water ad lib. DKA-M received NaCl 77 mmol/L 60 ml/kg (i.p.) q 4 hrs. on day 2. ...
Natelson B H - - 1992
OBJECTIVE: To evaluate the long-term consequences of stress in rats with genetic hypertension. DESIGN: Rapp-Dahl salt-sensitive rats, maintained on a low-salt diet, were stressed periodically over 8 weeks during which time their blood pressures were measured. In experiment 1 both stressed and unstressed control rats were given ad libitum access ...
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