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Results 451 - 500 of 617
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Norton J A - - 1985
To demonstrate that the anorexia and depletion of cachexia reverses on tumor removal, F344 rats underwent sarcoma resection when their food intake fell to 0 g/day. In survivors of surgery, reversal in food intake was apparent within 3 days postoperatively, followed after 2 days by gain in host weight. To ...
Freeman P H - - 1985
Adult female rats that underwent sympathectomy induced by guanethidine treatment (10, 20 or 40 mg/kg) exhibited markedly increased water intake, but did not display significant alterations of either food intake, body weight, or the Lee Index of obesity. Guanethidine treatment did not attenuate amphetamine anorexia as evidenced by comparable dose-dependent ...
Simansky K J - - 1985
Rats were restricted for three weeks to a schedule of 4-hr daily access to food. The regional concentrations of dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) in the forebrain were then determined after the rats: (1) were food-deprived overnight; (2) ate for the first hour of the scheduled feeding period; or ...
James J - - 1985
A simple automatic food dispensing machine can be used to train rats to a regime of meal-feeding during one hour at night. Apart from some 20% of the animals which fail to adapt but can be recognized early during training on the basis of weight curve, a population of animals ...
Friedman M I - - 1985
The effects of varying dietary fat content on food intake and metabolism in streptozotocin-diabetic rats were examined. The metabolic consequences of fat feeding were separated from the marked adjustments in voluntary food consumption that occur when diabetic rats are fed diets containing different amounts of fat by feeding rats a ...
Nichols M B - - 1985
In the present study, the relationship between central catecholamine levels and the anorexia induced by Walker 256 carcinoma was investigated. Results indicate that the anorexia is not due to depletion of central catecholamines. Tumor bearing rats sacrificed at night, when spontaneous food intake is selectively depressed, showed increased norepinephrine levels ...
Beauchamp G K - - 1985
Many studies have demonstrated that when sodium-replete rats are given a choice between water and isotonic saline, they consume more of the isotonic saline. Their ingestive responses to a choice between salted and unsalted food, however, have not been studied in the same detail. Because humans consume salt in or ...
Galef B G BG - - 1985
The present series of studies was undertaken to investigate the hypothesis (von F. Steiniger, 1950, Zeitschrift für Tierpsychologie, 7, 356-379; K. A. Stierhoff, & M. Lavin, 1982, Behavioral and Neural Biology, 34, 180-189) that rats poisoned after eating a novel food will mark that novel food in such a way ...
Pico R M - - 1985
The place behaviors of intact rats, and of those receiving fornix lesions, were examined in the radial-arm maze. A cue-restricted environment was constructed wherein the location of arms with food rewards were identifiable only by their position in relation to an intermittently rotated 4-cue set. Food obtainment was measured during ...
Peder M W - - 1985
The effects of daily 10-min mouse exposure tests on food consumption were studied in killer and non-killer Sprague-Dawley rats. The results showed both mouse-killers and non-killers significantly to decrease their food consumption when tested daily for mouse-killing. The effect was more pronounced in mouse-killers than in non-killers and the day-to-day ...
Fisler J S - - 1985
The effect of several drugs on food intake has been examined in two strains of rats, one (S 5B/P1) which is resistant to developing obesity when eating a high fat diet, and one (Osborne-Mendel) which readily develops obesity when eating the same diet. Insulin and 2-deoxy-D-glucose increased food intake in ...
Ikonomov O C - - 1985
The circadian rhythms of food and 1% NaCl intake, and urine, Na+, Cl- and K+ excretion were followed up in male Wistar rats before and one week after bilateral adrenalectomy at 4-hour intervals during two consecutive days. The circadian rhythms of plasma renin activity (PRA) and plasma immunoreactive insulin (IRI) ...
Harper D S - - 1985
Five well-characterized foods were used to compare two systems for estimating the cariogenic potential of food: human plaque-acidity using interdental metallic touch electrodes, and cariogenicity testing in rats. Both systems identified the same food as the least cariogenic or acidogenic food and identified the same three foods as being both ...
Canbeyli R S - - 1984
The significance of the upper small intestine in long-term regulation of food intake was investigated in pairs of parabiotic rats in which a 30 cm transected segment of each rat's intestine was sewn into continuity with the intestine of its partner. In this preparation, food eaten by one rat passes ...
Wellman P J - - 1984
The influence of 4-hydroxyamphetamine (4-OHAM) on food and water intake and in vivo brown adipose thermogenesis was examined in two experiments. In Experiment 1, female rats were treated with 0.00, 0.25, 0.50, 1.00, or 2.00 mg/kg 4-OHAM (ip) prior to assessment of interscapular brown adipose tissue (IBAT) thermogenesis. The 4-OHAM ...
McLaughlin C L - - 1984
Glucagon, a putative satiety peptide, has decreased food intake and antibodies to glucagon have increased food intake when administered acutely. It may be hypothesized if rats were immunized against glucagon, antibodies would chronically sequester glucagon released during meals and food intake and weight gain would increase. Female Zucker obese (n ...
Hallonquist J D - - 1984
Bilateral electrolytic (DC) or radiofrequency (RF) lesions of the ventromedial hypothalamic (VMH) area produced two abnormal stages of fattening in adult female rats. Following a negatively-accelerated, curvilinear phase of weight gain which lasted 10 weeks, a linear phase of fattening continued for an additional 30 weeks at a rate approximately ...
Borker A S - - 1984
The adult female rats hoard large quantities of food during proestrus and continue hoarding if ovariectomised at proestrus (Group I). The hoarding score is lowest in diestrus and continue to remain low if ovariectomised during this phase (Group II). The scores in Group I and Group II are reversed in ...
Britton D R - - 1984
The noradrenergic innervation of the forebrain by cells from the locus coeruleus (LC) was interrupted by either electrolytic lesions of the LC or 6-hydroxydopamine (6-OHDA) lesions of the dorsal noradrenergic bundle (DB). Animals so treated were then tested in a modified open field test designed to measure responsiveness to environmental ...
Czech D A - - 1984
The potential relationship between concomitant changes in feeding behavior and locomotor activity in rats exposed to tetraethyl lead (TTEL) was investigated. Two groups of rats were injected IP with a dose of TTEL (7 mg/kg) that depresses food intake. One group served as a control to replicate this effect. Animals ...
Aponte G - - 1984
We examined the possibility that somatostatin, a tetradecapeptide distributed in the gut and the central nervous system, may influence food intake and behavior in rats. Although intravenously infused somatostatin did not alter food intake in 8 hour fasted rats, intracerebroventricularly infused somatostatin resulted in a biphasic response, first increasing then ...
Geliebter A - - 1984
The effects of repeated administration of different macronutrient loads on spontaneous food intake and body weight of male Sprague-Dawley rats were studied. For 6 wk, eight groups of five rats each received two daily intragastric loads, 3.5 h apart, consisting of isocaloric amounts of one of the following: albumin, sucrose, ...
Palfai T - - 1984
Rats were lesioned bilaterally in the globus pallidus (GP) with anodal current or 6-OHDA, and were observed in various motor tests 10 min daily for 3 weeks. Body weight, home cage water and food intakes were recorded daily under two different food accessibility conditions. The lesions produced adipsia, aphagia, loss ...
Friedman M I - - 1984
Sectioning the hepatic branch of the anterior abdominal vagal trunk attenuated but did not abolish the normal nocturnal bias in the day-night distribution of food intake in female rats. Neither total daily food intake nor body weight was affected by hepatic vagotomy. This effect appeared to be specific to the ...
King B M - - 1984
The effects of ventromedial hypothalamic (VMH) lesions on plasma corticosterone, insulin, and glucose levels were studied in food-restricted and ad lib fed female rats. VMH lesions resulted in significant elevations of corticosterone and insulin levels compared to control values during the first 25 days after surgery. However, unlike insulin values ...
Oku J - - 1984
The addition of quinine to the food reversed the obesity in rats with hypothalamic hyperphagia induced by knife cuts. Similarly, the injection of quinine into rats with hypothalamic knife cuts reduced food intake and body weight but the effects were smaller than those observed when quinine was added to the ...
Lukaszewska I - - 1984
Twelve rats with amygdala damage (CBM) and 20 sham-operated controls were tested in several food-related situations. The CBM rats showed a longer latency to eat than controls in a novel environment due to more pronounced exploration. In the competition for food, CBM rats lost 85% of encounters with controls. Immediately ...
Stephan F K - - 1984
Rats anticipate daily 2 hr meals with a sharp increase in activity several hours prior to food availability. The present experiment examined the response to phase shifts of food access in rats with lesions of the suprachiasmatic nuclei (SCN). Following entrainment of activity to 2 hr of food per day, ...
Shirley B - - 1984
Quantities of food required by Sprague-Dawley rats during gestation and lactation and in the post-lactation period were examined. Rats allowed to eat ad libitum during pregnancy consumed quantities of food only slightly greater than the amount reported to be the average intake of pregnant Sprague-Dawley rats (20 g/day). Rats delivered ...
Reeves P G - - 1984
The study was designed to determine the effect of dietary tyrosine levels on food intake in the zinc-deficient rat. This was accomplished by using free L-amino acids as the source of nitrogen and manipulating the tyrosine concentrations in the diet. Results showed that low dietary tyrosine significantly increased food intake ...
Wager-Srdar S A - - 1984
Much evidence has accumulated indicating that cigarette smokers weigh less than non-smokers and that smokers gain weight when they cease smoking. In the present study we evaluated the effects of cigarette smoke and nicotine on food intake, weight gain, resting energy output, brown fat mass and opiate binding (opiates initiate ...
Kott J N - - 1984
The effect of hypophagia following lesions of the area postrema and caudal-medial aspect of the nucleus of the solitary tract AP/cmNTS) on body-weight, water intake and preference for palatable diets was examined. Following AP/cmNTS ablation, rats reduced pelleted-food intake to a degree which was sufficient to account for the weight ...
Itano N - - 1984
The effect of cecectomy on food intake and defecation was studied in Wistar rats fed ad libitum or under restriction. Food intake, fecal output, dry matter and water content of feces, and numbers of scybala increased significantly in both groups of cecectomized rats. The weight of scybala and their dry ...
Behm R - - 1984
Spontaneously hypertensive rats (SHR) of the Okamoto-Aoki-strain (n = 20) and normotensive rats (NCR) of a random-bred Wistar strain (n = 20) were kept in low-pressure chambers for 13 days at sea-level atmospheric pressure, then for 20 days at a simulated altitude of 4000 m, and subsequently again for 10 ...
Dallman M F - - 1984
The relationships among food intake, insulin secretion, and adrenocortical function are reviewed. It is hypothesized that a major role of structures in, or passing through, the ventromedial hypothalamus is to inhibit food intake, insulin secretion, and adrenocortical function during the day (in the nocturnally active rat) and that this activity ...
Bryant K R - - 1984
Presenting rats with a 0.9 per cent sodium chloride solution to drink instead of water had little or no effect on body weight gain and food intake, but resting oxygen consumption and total energy expenditure (corrected for body size) were elevated, and thermogenic responses to both noradrenaline and a meal ...
South E H - - 1983
Lesions which destroy the area postrema (AP) and damage the adjacent nucleus of the solitary tract (NST) produce a constellation of behavioral signs which include overingestion of highly palatable food, exaggerated drinking in response to angiotensin II, diminished feeding in response to glucoprivation and chronically reduced body weight. The diversity ...
Sahakian B J - - 1983
Three experiments contrasted the effects of 6-hydroxydopamine-induced lesions of the ventral noradrenergic and dorsal noradrenergic projections, predominantly to hypothalamus and cortex, respectively, upon body weight changes and food-related behaviour in the rat. In general, ventral noradrenergic bundle lesions enhanced weight gain and these effects were exaggerated by the provision of ...
Gadeholt G - - 1983
The effect of intragastric ethanol, 7.8 g/kg, on the microsomal enzyme activities NADPH cytochrome c reductase, aminopyrine N-demethylase and aniline hydroxylase, were investigated in two sizes (150 g and 260 g) of mature male rats having free access to food and water for the 23 hours following ethanol administration. Controls ...
Matsuo T - - 1983
Male weanling rats, fed a riboflavin-deficient diet for 14 days showed impairments in reactivity to the hyperphagic action of either insulin or 2-deoxy-D-glucose (2DG) and in sensitivity to the diabetogenic action of streptozotocin or alloxan. The intraperitoneal injection of riboflavin (160 micrograms/rat) resulted in an immediate restoration in FAD-dependent activation ...
Stoloff M L - - 1983
To help identify determinants of rat appetitive behavior during the weanling period, rat pups 17-32 days of age were studied in a Y-maze. One arm of the maze provided pups with the opportunity to suckle a lactating or nonlactating anesthetized female. The other arm always contained a familiar food, either ...
Navia J M - - 1983
Using standard reference snack foods, we tested a method, using rats fed in a programmed feeding machine, to evaluate the caries-promoting properties of foods. Results, which were expressed in relation to a control food, indicate that the method distinguished differences in caries potential among a number of different snack foods. ...
Reinhardt M C - - 1983
Intestinal uptake of antigenically intact food proteins was measured by a solid phase radioimmunoassay on serum samples after instillation of food proteins into a closed intestinal loop of adult Wistar rats. Compared to normal controls, rats fed protein deficient diets during five months had a higher macromolecular uptake. During the ...
Cabanac M - - 1983
Rats were trained to feed each day from 10 o'clock to 12 noon. Once a week in an environment of Ta--15 degrees C, additional food was made available 16 m from a thermoneutral refuge. The additional food offered was either shortcake, meat pâté, peanut butter, Coca-cola, all of these (cafeteria), ...
Kunihara M - - 1983
The present study was undertaken to examine how morphine changes food and water intake in non-fasted or fasted rats with different administration times. Morphine (1, 3 and 10 mg/kg) was intraperitoneally administered at 10:45 (light period) or 18:45 (dark period). Morphine increased food and water intake in non-fasted rats 2 ...
Munday M R - - 1983
Despite the hyperphagia, the food intake of the lactating rat showed marked diurnal changes which paralleled those of virgin rats. The major difference was that lactating rats consumed a higher proportion (35%) of their diet during the light period than did virgin rats (14%). The peak rate of lipogenesis in ...
Kaiser C A - - 1983
In order to compare phenolic and tyrosyl ring monodeiodination, we investigated 3'-isopropyl-3,5-diiodo-L-thyronine (DIIP), a potent thyronine analog which can only be monodeiodinated on the tyrosyl ring. A specific RIA was developed. The in vivo metabolism and biological potency of DIIP and T3 were compared. DIIP and T3 kinetic studies were ...
Rolls B J - - 1983
Male and female rats were given three palatable, high energy foods either simultaneously or in succession during three 40 min courses. Both simultaneous and successive variety enhanced energy intake compared to the intake of single palatable foods, which was itself enhanced compared to the intake of chow. Rats deprived of ...
Lind R W - - 1983
Rats prescreened for responses to dipsogens received anteroventral third cerebral ventricular (AV3V) or sham lesions (ether anesthesia). Many known effects of AV3V lesions were observed, and new findings include a failure to drink adequately in response to polyethylene glycol (PEG) and water deprivation (regardless of responses to other dipsogens) and ...
Nichols M - - 1983
The role of brain serotonin levels in Walker 256 tumor induced anorexia was investigated. Total and free plasma tryptophan, regional brain serotonin and 5-hydroxyindoleacetic acid were determined at night, and their relationship to nocturnal anorexia assessed by linear regression analysis. No significant difference in tryptophan, serotonin, or 5-hydroxyindoleacetic acid levels ...
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