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Daripa Mandira - - 2013
OBJECTIVE: To compare the epidemiological profile of avoidable early neonatal deaths associated with perinatal asphyxia according to region of death in the State of São Paulo, Brazil. METHODS: Population-based cohort study including 2,873 avoidable deaths up to six days of life associated with perinatal asphyxia from January 2001 to December ...
Fox Jocelyn E Manning - - 2013
Our understanding of adult human β-cells is advancing, but we know little about the function and plasticity of β-cells from infants. We therefore characterized islets and single islet cells from human infants after isolation and culture. Although islet morphology in pancreas biopsies was similar to that in adults, infant islets ...
Lavezzi Anna M - - 2013
We investigated the locus coeruleus complex in the brainstems of 78 subjects aged from 24 gestational weeks to 8 postnatal months, who died of unknown (sudden unexplained fetal and infant deaths) and known causes (controls). The goals of this study were: (1) to obtain basic information about the morphology of ...
Pane Masdalina - - 2013
Indonesia provides the largest single source of pilgrims for the Hajj (10%). In the last two decades, mortality rates for Indonesian pilgrims ranged between 200-380 deaths per 100,000 pilgrims over the 10-week Hajj period. Reasons for high mortality are not well understood. In 2008, verbal autopsy was introduced to complement ...
McPherson Duncan D Imperial College London, London, - - 2013
To quantify mortality associated with sepsis in the whole population of England. Descriptive statistics of multiple cause of death data. England between 2001 and 2010. All people whose death was registered in England between 2001 and 2010 and whose certificate contained a sepsis-associated International Classification of Diseases, 10th Revision (ICD-10) ...
Lavezzi A M AM Anna Maria Lavezzi, "Lino Rossi" Research Centre for the study and prevention of unexpected perinatal death and SIDS, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via della Commenda 19, 20122 Milano, Italy, phone: +39-02-50320821, fax: +39-02-50320823, e-mail: - - 2013
The present study was aimed at supplementing our previous investigations on the morphological features of the Purkinje cells during the autonomic nervous system development, particularly in victims of sudden perinatal death (Sudden Intrauterine Unexplained Death Syndrome and Sudden Infant Death Syndrome), given their crucial role in determining connectivity patterns in ...
Tassell-Matamua Natasha A - - 2014
Little is known about the psychological phenomenology of death. Reported across known history and in all cultures by those who have died or been close to death, NDEs challenge objective-mechanistic models by suggesting the phenomenology of death may involve a variety of complex psychological processes. This article discusses three notable ...
Gee Sarah N - - 2012
Multiorgan Langerhans cell histiocytosis (LCH) presenting in the neonatal period is associated with a poor prognosis. We report a 5-day-old neonate who presented at birth with diffuse cutaneous nodules and respiratory failure who received a postmortem diagnosis of LCH. We emphasize the importance of recognizing the cutaneous findings of this ...
Munjal Kevin G - - 2013
In the United States, when people die unexpectedly, they are usually not considered as organ donors because of the difficulty of keeping organs viable when death occurs outside the hospital, in "uncontrolled" circumstances. New protocols to permit donation in these cases have renewed the debate about how we decide whether ...
Wilson Ann L - - 2012
The 2011 annual report of the Regional Infant and Child Mortality Review Committee (RICMRC) is presented. Since 1997, the committee has reviewed 224 deaths to achieve its mission to "review infant and child deaths so that information can be transformed into action to protect young lives." In 2011, the committee ...
Nakibuuka Vk - - 2012
The perinatal mortality of 70 deaths per 1,000 total births in Uganda is unacceptably high. Perinatal death audits are important for improvement of perinatal care and reduction of perinatal morality. We integrated perinatal death audits in routine care, and describe its effect on perinatal mortality rate at Nsambya Hospital. This ...
Leary Peter J PJ Department of Obstetrics and Gynecology and Divisions of Pulmonary and Critical Care Medicine and Cardiology, University of Washington Medical Center, Seattle, Washington 98195-6522, USA. - - 2012
To explore the association between the presence of maternal heart disease and maternal, perinatal, and infant outcomes. We conducted a population-based retrospective cohort study using Washington State birth certificates linked with hospital discharge records of mothers noted to have maternal congenital heart disease, ischemic heart disease, heart failure, or pulmonary ...
Guly Henry - - 2012
This year, 2012, marks the 100th anniversary of Captain Scott his reaching the South Pole and of his death on the return journey. There has been much discussion on the cause of death of Scott and his colleagues and, in particular, whether he died of scurvy. There has probably been ...
Johansson Jens - - 2012
Those who endorse the view that death is in some cases bad for the deceased-a view that, as I shall explain, has considerable bearing on many bioethical issues-need to address the following, Epicurean question: When is death bad for the one who dies? The two most popular answers are "before ...
Bunders Madeleine J - - 2012
Despite potential clinical importance, target cells for HIV-1 in mother-to child-transmission (MTCT) have not yet been identified. Cord blood-derived CD4(+) T cells are largely naïve and do not express CCR5, the mandatory co-receptor for transmitted HIV-1 R5 strains in infants. Here, we demonstrate that in the human fetal and infant ...
Penn Alexander H AH Department of Bioengineering, University of California, San Diego, La Jolla, California, USA. - - 2012
Premature infants fed formula are more likely to develop necrotizing enterocolitis (NEC) than those who are breastfed, but the mechanisms of intestinal necrosis in NEC and protection by breast milk are unknown. We hypothesized that after lipase digestion, formula, but not fresh breast milk, contains levels of unbound free fatty ...
The Japanese Congenital Cytomegalovirus Infection Immunoglobulin Fetal Therapy Study - - 2012
No medical intervention guideline for prenatally diagnosed symptomatic congenital cytomegalovirus infection (CCMVI) is currently available. The aim of the study was to assess the efficacy of immunoglobulin fetal therapy for symptomatic CCMVI. With informed consent, hyper-immunoglobulin was injected into the peritoneal cavity of affected fetuses or into the maternal blood ...
Chowdhury Olie - - 2012
Infants born at term requiring mechanical ventilation suffer significant mortality and morbidity, yet few studies have tried to identify the optimum respiratory support for such infants. We, therefore, hypothesised that practice would vary, particularly between different levels of neonatal care provision. The lead clinicians of all 212 UK neonatal units ...
Lorch Scott A SA The Children's Hospital of Philadelphia, Center for Outcomes Research, 3535 Market St, Suite 1029, Philadelphia, PA 19104, USA. - - 2012
Because greater percentages of women deliver at hospitals without high-level NICUs, there is little information on the effect of delivery hospital on the outcomes of premature infants in the past 2 decades, or how these effects differ across states with different perinatal regionalization systems. A retrospective population-based cohort study was ...
Tang Brian G BG Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA. - - 2012
Using a statewide population-based data source, we describe current neonatal follow-up referral practices for high-risk infants with developmental delays throughout California. From a cohort analysis of quality improvement data from 66 neonatal follow-up programs in the California Children's Services and California Perinatal Quality Care Collaborative High-Risk Infant Follow-Up Quality of ...
Haddad Lisa - - 2012
To compare temperature readings of temporal artery and axillary thermometers in healthy late preterm and term infants in an effort to standardize practice. Descriptive comparative. Thirty-bed, healthy mother/baby unit in an inner-city Level-1 trauma center, averaging 2,500 births per year. Healthy newborns (N = 125) admitted to mother/baby unit after ...
van der Linden Marieke H - - 2012
Leukaemia in neonates (infants <1 month) is rare, whereby neonatal acute myeloid leukaemia (AML) is more frequent than neonatal acute lymphoblastic leukaemia (ALL). High mortality rates are observed, though AML has a better prognosis than ALL. Neonatal leukaemia is typically presented with hepatosplenomegaly, leukaemia cutis and/or hyperleucocytosis. Congenital infections should ...
Dusing Stacey C - - 2012
Infants born preterm are at high risk of developmental disabilities and benefit from early developmental intervention programs. Physical therapists with neonatal expertise are ideally suited to educate parents about ways to support their infant's development in the first months of life. However, administrative policies are needed to support the therapist ...
Garten L - - 2012
Objective:To study the experiences and needs of the fathers of very low birth weight (VLBW, <1500 g) infants in a neonatal intensive care unit (NICU).Study Design:An anonymous self-report questionnaire was administered to fathers of VLBW infants born between Jan 1, 2008 and December 31, 2009 at two tertiary NICUs.Result:A total of ...
Grover S S - - 2012
The level of circulating tetanus toxin, antitoxin and their individual influence on the outcome of tetanus cases were determined in unimmunized 125 neonatal and 39 infant cases of tetanus. PHA (passive haemagglutination) test showed 40% positive cases for toxin while its absence in the remaining cases indicated of either toxin ...
Ross Julie A JA Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA. - - 2013
The mixed lineage leukemia (MLL) gene is commonly rearranged in infant leukemia (IL). Genetic determinants of susceptibility to IL are unknown. Recent genome-wide association studies for childhood acute lymphoblastic leukemia (ALL) have identified susceptibility loci at IKZF1, ARID5B, and CEBPE. We genotyped these loci in 171 infants with leukemia and ...
Brooks Stacey - - 2012
Objective: Patients' views of illness are often thought to differ from those of medical staff, although this is rarely assessed. This study examined the correspondence between mothers' and clinicians' perceptions of the same high-risk newborns, as well as with an objective measure of illness severity. We also investigated how mothers' ...
Greer Frank R - - 2012
ABSTRACT: Potentially harmful effects of early, high does intravenous amino acids (4g/kg/d) are reported for growth and neurodevelopmental outcomes in extremely low birth weight infants. Until larger randomized controlled trials with long term outcomes can be completed, neonatologists should proceed with caution with early administration of large amounts of intravenous ...
Tagliabue Paolo - - 2012
Abstract Term "high risk newborns" identifies a group of newborns who very likely will develop a severe acute disease or an adverse outcome. Every day Neonatologists are faced with high risk newborns that represent the majority of patients admitted to the neonatal intensive care units. Particularly, term newborns with hypoxic-ischemic ...
Hopewell J - - 2012
Parenteral nutrition (PN) plays an important role in providing nutrients for infants unable to tolerate enteral feeds study was to look at PN prescribing in neonatal units in the United Kingdom (U.K.) and Ireland, in particular in infants < 1.5 kg. A postal questionnaire was administered to the 235 neonatal ...
von Lindern Jeannette S - - 2012
ObjectiveTo study whether the incidence of intraventricular haemorrhage (IVH) in very premature infants (<32 weeks gestation) with thrombocytopaenia is lower when using a liberal platelet-transfusion guideline compared with a restrictive guideline.Study designA retrospective cohort study comparing the incidence of IVH in very premature infants with thrombocytopaenia (platelet count <150×10(9)/l) admitted ...
Verma Prashant - - 2012
  Neonatal purpura fulminans is rare and may be inherited or acquired. It may ultimately lead to multiorgan failure and death. Purpura fulminans in a premature neonate resulting from Staphylococcus aureus septicemia is illustrated. Unfortunately, the baby succumbed to septicemia.
Gallagher Joel L - - 2012
Hizentra® is a 20% liquid IgG product approved for subcutaneous administration in adults and children greater than 2 years of age. We report two infants less than 2 years in which administration of Hizentra® was safe and effective.
Husain Entesar H - - 2012
Infants represent an important risk group for influenza associated hospitalizations and mortality. This study evaluated the clinical presentations, hospitalization course and outcome of infants hospitalized with the pandemic influenza A H1N1 [Influenza A(H1N1)pdm09] in relation to their previous health status. We conducted a retrospective chart review of hospitalized infants with ...
Agarwal Manisha M Reader, Department of Pedodontics and Preventive Dentistry, AECS Maaruti College of Dental Sciences and Research Centre, Bengaluru Karnataka, India, e-mail: - - 2012
Breastfeeding is a natural safety-net for the first few months in order to give the child a fairer start to life. The American Academy of Pediatric Dentistry recognizes the distinct nutritional advantages of human milk for infants and endorsed the position of the American Academy of Pediatrics on the promotion ...
Bakermans-Kranenburg Marian J MJ Centre for Child and Family Studies, Leiden University, The Netherlands. - - 2012
Infant crying can elicit sensitive caregiving as well as hostility and harsh parenting responses. In the current study (N = 42 females) with a double-blind experimental design, we tested the effect of intranasal oxytocin administration on the use of excessive force using a hand-grip dynamometer during listening to infant cry ...
Alletag Michelle J - - 2011
The use of bedside emergency ultrasound in pediatric abdominal emergencies is becoming more widespread and can be a useful adjunct in the assessment of children who present with abdominal pain. Our case describes an infant who presented to the emergency department with vomiting, in whom an emergency ultrasound evaluation led ...
Stein Alan - - 2012
Difficulties in mother-child interaction are commonly observed in the context of postnatal depression. These difficulties may result in part from the negative cognitive bias present in depression, which may in turn lead to biased negative perceptions of the infant: in particular, these biases encompass the negative appraisal of facial expressions. ...
Oden Rosalind P - - 2011
Introduction. The supine sleep position is recommended to reduce sudden infant death syndrome risk. Swaddling may improve adherence with supine placement. Aim. To assess knowledge, attitudes, and practice regarding swaddling among adult caregivers of 0- to 3-month-old infants. Methods. Cross-sectional descriptive survey. Results. All 103 adults interviewed had swaddled their ...
Haward Marlyse F - - 2011
Decision-making for extremely immature preterm infants at the margins of viability is ethically, professionally, and emotionally complicated. A standard for prenatal consultation should be developed incorporating assessment of parental decision-making preferences and styles, a communication process involving a reciprocal exchange of information, and effective strategies for decisional deliberation, guided by and consistent with ...
Balas Benjamin - - 2011
The 'other-race' effect describes the phenomenon in which faces are difficult to distinguish from one another if they belong to an ethnic or racial group to which the observer has had little exposure. Adult observers typically display multiple forms of recognition error for other-race faces, and infants exhibit behavioral evidence ...
Yu Jae Eun - - 2010
Major full-thickness burn injuries in newborns are rare but have been reported following the use of medical and warming devices during the early neonatal period. In this report, we present a newborn infant with major full-thickness contact burn injuries of 15% of the total body surface area (TBSA) caused by ...
Bath Debra M DM School of Psychology, Griffith University, Gold Coast, Queensland, Australia. - - 2010
Individuals' death anxiety or fear of death has been extensively investigated, and there are numerous conceptualizations used in the literature, including a distinction between the dimensions of death and dying of self and death and dying of others. This article addresses a gap in the literature and re-examines the relationship ...
Ritchie Jennifer M JM Channing Laboratory, Brigham and Women’s Hospital, Boston, Massachusetts, - - 2010
Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V. cholerae into 3-day-old rabbits pretreated with cimetidine led to lethal, watery diarrhea in virtually all rabbits. The appearance and chemical composition of ...
Sato Y - - 2010
BACKGROUND: Grafting of testicular tissue into immunodeficient mice has been used to differentiate the neonatal testes from different animal species up to the level of complete spermatogenesis; however, this approach has not been successful for human testicular tissue. The aim of this study was to evaluate the capacity for differentiation ...
Tripathi B M - - 2010
Usage of psychotropics during pregnancy and lactation has always been a topic of debate and controversy. The debate stems from the potential adverse effects on the growing fetus or infants due to the transfer of psychotropic drugs through placenta or breast milk of mothers receiving them; and the problem of ...
Sadoh Ayebo E - - 2008
High neonatal mortality is the hallmark of developing countries. Most of the deaths are preventable by good antenatal care with risk identification and access to safe delivery. However, only about a third of births are attended by skilled personnel in Nigeria. The case of a newborn (one of a set ...
Burlinson Clare E G - - 2009
INTRODUCTION: This study was undertaken after an increasing trend in young babies presenting with severe burns was observed in Princess Margaret Hospital (PMH) in Perth, Western Australia. The aim was to explore the patterns of these injuries with a view to identifying whether they could be prevented with better parent ...
Wang Xue-Qing - - 2009
This retrospective review examines healing in different sites on a porcine burn model; 24 pairs of burns on 18 pigs from other animal trials were selected for analysis. Each pair of burns was located on the either the cranial or the caudal part of the thoracic ribs region, on the ...
Nguyen Dai Q A - - 2008
A wealth of data exists concerning paediatric burn epidemiology in general, but very little exists specifically in infants under 1 year of age, a special group in which mobility begins to develop. A retrospective study of all burn admissions of infants under 1 year old to The Welsh Centre for ...
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