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Cristia Alejandrina A Neurobiology of Language, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands. - - 2013
Until recently, imaging the infant brain was very challenging. Functional Near InfraRed Spectroscopy (fNIRS) is a promising, relatively novel technique, whose use is rapidly expanding. As an emergent field, it is particularly important to share methodological knowledge to ensure replicable and robust results. In this paper, we present a community-augmented ...
Roisman Glenn I GI University of Minnesota, Minneapolis, MN, USA. - - 2013
This paper advises caution in relation to the increasing interest in molecular-genetic association studies in developmental psychology based on a set of empirical examples from the NICHD Study of Early Child Care and Youth Development (SECCYD) that highlight the fragility of effects reported in the literature on the molecular-genetic correlates ...
Richardson Sandra D - - 2013
Introduction: Birth defects surveillance programs support efforts to prevent and address population health. For 30 years, the New York State (NYS) Department of Health (DOH) Congenital Malformations Registry (CMR) has been receiving reports of children with birth defects diagnosed from birth to age 2 years as required by NYS DOH ...
Li Gang G Department of Radiology and BRIC, University of North Carolina at Chapel Hill, NC, - - 2013
Accurate and consistent labeling of longitudinal cortical surfaces is essential to understand the early dynamic development of cortical structure and function in both normal and abnormal infant brains. In this paper, we propose a novel method for simultaneous, consistent, and unbiased labeling of longitudinal dynamic cortical surfaces in the infant ...
Tiemersma Sybrich - - 2012
Abstract Background: Aerosol therapy in preterm infants is challenging, as a very small proportion of the drug deposits in the lungs. Aim: Our aim was to compare efficiency of standard devices with newer, more efficient aerosol delivery devices. Methods: Using salbutamol as a drug marker, we studied two prototypes of ...
Lewis Zachery T - - 2012
Bifidobacteria are intestinal anaerobes often associated with gut health. Specific bifidobacterial species are particularly common in the gastrointestinal tract of breast-fed infants. Current short read next-generation sequencing approaches to profile fecal microbial ecologies do not discriminate bifidobacteria to the species level. Here we describe a low-cost terminal restriction fragment length ...
Gupta Raegan Wetzel - - 2012
OBJECTIVES:: Bacterial colonization is considered a major risk factor for necrotizing enterocolitis. The objective of this study was to test the hypothesis that Histamine-2 receptor blockers alter colonic bacterial colonization by analyzing and comparing the fecal microbiota in premature infants with and without Histamine-2 receptor blocker therapy using sensitive molecular ...
Kozák Lajos R - - 2012
Diffusion weighted magnetic resonance imaging is increasingly being used for neonatal and young pediatric subjects. Our purpose was to investigate a) whether cardiac triggering was needed to reduce variability of diffusion (tensor) imaging data, b) how pulsation artifacts affect the fitted diffusion tensor when triggering is not used and c) ...
Macari Suzanne L - - 2012
The study examined whether performance profiles on individual items of the Toddler Module of the Autism Diagnostic Observation Schedule at 12 months are associated with developmental status at 24 months in infants at high and low risk for developing Autism Spectrum Disorder (ASD). A nonparametric decision-tree learning algorithm identified sets ...
Meadow William - - 2012
This article discusses the ethical issues surrounding the resuscitation of infants who are at great risk to die or survive with significant morbidity. Data are introduced regarding money, outcomes, and prediction. Gestational age influences some of the outcomes after birth more than others do. Prediction is possible at four stages ...
Kumar Tarun - - 2012
Infants born with gastroschisis in association with intestinal atresia are well described. We are the proposing the classification of vanishing gastroschisis. In this series of six cases, at one end of the spectrum is an infant having gastroschisis with a much narrower defect on the right side of umbilicus. The ...
Bream Elise N A EN Department of Pediatrics, University of Iowa, Iowa City, Iowa, - - 2013
The aim of this study was to identify genetic variants contributing to preterm birth (PTB) using a linkage candidate gene approach. We studied 99 single-nucleotide polymorphisms (SNPs) for 33 genes in 257 families with PTBs segregating. Nonparametric and parametric analyses were used. Premature infants and mothers of premature infants were ...
Shin Hyunju - - 2013
An isotope dilution LC/mass spectrometric (ID-LC/MS) method was developed as a candidate reference method for the accurate determination of niacin in infant formula, breakfast cereals and multivitamin. After spiking nicotinamide-d(4) as an internal standard, infant formula and breakfast cereal samples were hydrolysed under alkaline condition. Samples were then analysed in ...
Lam Sandi - - 2012
Meconium staining of open myelomeningoceles has been reported to occur both prenatally and postnatally, but meconium staining of the brainstem has not been previously documented. The authors present a case of meconium staining of the brainstem in an infant with a meconium-stained myelomeningocele, Chiari malformation Type II, and hydrocephalus and ...
Bose Carl L CL Department of Pediatrics, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA. - - 2013
Little evidence is available to document that mechanical ventilation is an antecedent of systemic inflammation in preterm humans. We obtained blood on postnatal day 14 from 726 infants born before the 28th week of gestation and measured the concentrations of 25 inflammation-related proteins. We created multivariable models to assess the ...
Mallin Brittany M BM Division of Epidemiology, University of - - 2012
This study examined the effect of attention in young infants on the saccadic localization of dynamic peripheral stimuli presented on complex and interesting backgrounds. Infants at 14, 20, and 26 weeks of age were presented with scenes from a Sesame Street movie until fixation on a moving character occurred and ...
Frankenhuis Willem E WE Cognitive Development Center, Central European University, Hattyú u. 14, 1015 Budapest, Hungary. - - 2013
Two significant questions in cognitive and developmental science are first, whether objects and events are selected for attention based on their features (featural processing) or the configuration of their features (configural processing), and second, how these modes of processing develop. These questions have been addressed in part with experiments focused ...
Manduca Antonia - - 2012
Abstract Mother-infant interactions are essential for proper neurobehavioral development of the offspring, and disruptions in those relationships may result in neuroendocrine, neurochemical and behavioral alterations at adulthood. The neural circuitries involved in mother-infant interactions have not been completely elucidated yet. The brain endocannabinoid system plays an essential role in prenatal ...
Saunders Carol Jean - - 2012
Monogenic diseases are frequent causes of neonatal morbidity and mortality, and disease presentations are often undifferentiated at birth. More than 3500 monogenic diseases have been characterized, but clinical testing is available for only some of them and many feature clinical and genetic heterogeneity. Hence, an immense unmet need exists for ...
Boisvert Michel R - - 2012
Aim: To identify, using capillary electrophoresis and chemometrics, early biomarkers in human amniotic fluid of large-for-gestational-age (LGA) infants. Materials & methods: Second trimester amniotic fluid samples, obtained from mothers undergoing age-related amniocentesis, were analyzed by capillary electrophoresis. Electropherogram data were aligned using correlation-optimized warping. A genetic algorithm using a Bayesian ...
Dai Yakang - - 2012
It's a great challenge to analyze infant brain MR images due to the small brain size and low contrast of the developing brain tissues. We have developed an Infant Brain Extraction and Analysis Toolbox (iBEAT) for various processing of magnetic resonance (MR) images of infant brains. Several major functions generally ...
Konar Hiralal H Department of Obstetrics & Gynaecology, Calcutta National Medical College & Hospital, CD-55, Salt Lake City, Sector-1, Kolkata, 700 064 - - 2013
The aim of this study of maternal deaths through FOGSI members is to see its current STATUS. A three-year retrospective observational study from January 2005 to December 2007 formed the basis for collection of the data for analysis. A wide variation of maternal mortality ratio (MMR) in the five zones ...
Mitchell Timothy J - - 2012
OBJECTIVE: To implement an automated analysis of EEG recordings from prematurely-born infants and thus provide objective, reproducible results. METHODS: Bayesian probability theory is employed to compute the posterior probability for developmental features of interest in EEG recordings. Currently, these features include smooth delta waves (0.5-1.5Hz, >100μV), delta brushes (delta portion: ...
Agrawal Saurabh - - 2012
Ultrasonography is an emerging tool for monitoring clubfoot correction and for early diagnosis of spurious correction and of deformity recurrence. Sonography is widely available, inexpensive and has dynamic capability and can visualize tarsals in infants accurately.
Drysdale Simon B - - 2012
A systematic literature review has been undertaken. Respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) in infancy is associated with chronic respiratory morbidity. Premorbid abnormal lung function may predispose to RVS LRTI in prematurely born infants. Conclusion:  Single-nucleotide polymorphisms in genes coding for IL-8, IL-19, IL-20, IL-13 mannose-binding lectin, ...
Wass S V - - 2012
Researchers studying infants' spontaneous allocation of attention have traditionally relied on hand-coding infants' direction of gaze from videos; these techniques have low temporal and spatial resolution and are labor intensive. Eye-tracking technology potentially allows for much more precise measurement of how attention is allocated at the subsecond scale, but a ...
Ellingson David - - 2012
A method for the analysis of free and total myo-inositol in foods, feeds, and infant formulas has been developed and validated using high-performance anion exchange chromatography with pulsed amperometric detection. The option of a free myo-inositol determination or a complete total myo-inositol determination from main bound sources can be achieved. ...
Fujiwara Toshihiro - - 2012
Abstract We report an exacerbation of congenital oesophageal stenosis caused by accidental ingestion of tape that had been placed on a postoperative scar of the right thumb. Treatment by tape fixation in infants with gastrointestinal disease should be carefully monitored.
Standley Jayne - - 2012
Purpose: To provide an overview of developmental and medical benefits of music therapy for preterm infants.Design: Meta-analysis.Sample: Empirical music studies with preterm infants in the neonatal intensive care unit (NICU).Main Outcome: Evidence-based NICU music therapy (NICU -MT ) was highly beneficial with an overall large significant effect size (Cohen's d ...
Zosh Jennifer M - - 2012
Accurate representation of a changing environment requires individuation-the ability to determine how many numerically distinct objects are present in a scene. Much research has characterized early individuation abilities by identifying which object features infants can use to individuate throughout development. However, despite the fact that without memory featural individuation would ...
Clifford Sally M - - 2012
The current study investigated early temperament in 54 infants at familial high-risk of ASD and 50 controls. Parental report of temperament was assessed around 7, 14 and 24 months of age and diagnostic assessment was conducted at 3 years. The high-risk group showed reduced Surgency at 7 and 14 months and reduced Effortful ...
Cizmeci Mehmet Nevzat - - 2012
Follow-up of premature infants in the outpatient clinics after graduation from the NICU, is a challenging issue for both parents and doctors. With an increasing number of survival of the premature infants, maintaining the quality of life and timely diagnosis of the late-onset complications have become the focus of care ...
Ahn Hye Mi - - 2012
Background: Despite continuous research on the prevention of preterm labor, preterm delivery still occurs often. Different neonatal outcomes in association with chorioamnionitis might occur with the introduction of antenatal steroids. Objective: The purpose of this study was to determine the effect of chorioamnionitis on the outcome of preterm infants and ...
Ohye Richard G - - 2012
The Single Ventricle Reconstruction trial randomized 555 subjects with a single right ventricle undergoing the Norwood procedure at 15 North American centers to receive either a modified Blalock-Taussig shunt or right ventricle-to-pulmonary artery shunt. Results demonstrated a rate of death or cardiac transplantation by 12 months postrandomization of 36% for ...
Nicholson George T - - 2012
Infants with congenital heart disease have impaired weight gain during the first several months of life. Efforts have focused on improving weight gain and nutritional status during the first months of life. Close examination of the data suggests that the immediate postoperative period is problematic. Etiology of this early growth ...
Tricarico Antonella - - 2012
INTRODUCTION: Bednar aphthae are infected wounds caused by trauma, localized to the hard palate in infants. They do not require specific treatment because they regress spontaneously in a few days. They often remain undiagnosed; other times, because of the pain they caused, they may worsen the nursing. CASE REPORT: We ...
Malhotra Atul - - 2012
Acquired tracheobronchomalacia (TBM) is an uncommon complication of severe lung disease in infancy. We report a case of TBM in an ex-premature infant with severe chronic lung disease (CLD). Multidetector computed tomography (MDCT) was used to dynamically assess the patency of the large airways at different time periods during the ...
Mortenson Patricia - - 2012
As the incidence of deformational plagiocephaly (DP) has risen, so has the demand on clinicians to make appropriate treatment recommendations. While knowledge of risk factors and natural history continue to evolve, there is uncertainty and controversy regarding intervention approaches. The purpose of this report is to review current treatment approaches ...
Leone Daniela - - 2012
BACKGROUND: Several studies have reported on neonatal tremors or "jitteriness" or, as described by Precthl "hyperexcitability syndrome" including tremors and increased resistance to passive movement. AIM: To describe the evolution of signs and the outcome at one year in low risk term born infants with neonatal tremors persisting beyond 10days. ...
Johnson Amy M - - 2012
Abstract Despite the known health benefits for mother and infant, compliance with exclusive breastfeeding continues to challenge many healthcare providers. In an ongoing attempt to maintain the goals of the Healthy People 2010 initiative, our institution set out to identify patients with suboptimal breastfeeding rates in order to recognize potential ...
Blinman Thane - - 2012
This article discusses the potential benefits and challenges of minimally invasive surgery for infants and small children, and discusses why pediatric minimally invasive surgery is not yet the surgical default or standard of care. Minimally invasive methods offer advantages such as smaller incisions, decreased risk of infection, greater surgical precision, ...
Breschan Christian - - 2012
Background:  In this study, we analyze the impact of the choice of either the left or right brachiocephalic vein (BCV) on the cannulation success when using the ultrasound-guided supraclavicular in-plane technique approach to the longitudinally viewed BCV in infants. Methods:  The central vascular protocols of 183 infants were reviewed retrospectively. ...
Whyte Robin K - - 2012
Surviving extremely low-birth-weight infants are at risk of severe neurodevelopmental disability. Transfusion with packed red cells is almost universal in the care of these infants, but the hemoglobin threshold at which these transfusions should be given is unclear. Different clinical trials of restrictive (low hemoglobin) versus liberal (high hemoglobin) thresholds ...
Ahmed Rehan - - 2012
Neonatal seizures patterns evolve with changing frequency, morphology and propagation. This study is an initial attempt to incorporate the characteristics of temporal evolution of neonatal seizures into our developed neonatal seizure detector. The previously designed SVM-based neonatal seizure detector is modified by substituting the Gaussian kernel with the Gaussian dynamic ...
Watemberg Nathan - - 2012
Infantile spasms (IS) represent a major therapeutic challenge, as cessation of spasms and normalization of the electroencephalogram (elimination of hypsarrhythmia) are mandatory to prevent cognitive deterioration in previously healthy infants, or to preserve neurocognitive function among those neurologically affected prior to onset of IS. Traditionally, this epilepsy syndrome has been ...
Hogan Alexandra M - - 2012
Executive dysfunction occurs in sickle cell anemia, but there are few early data. Infants with sickle cell anemia (n = 14) and controls (n = 14) performed the "A-not-B" and Object Retrieval search tasks, measuring precursors of executive function at 9 and 12 months. Significant group differences were not found. ...
Watson Linda R LR The University of North Carolina at Chapel Hill, USA. - - 2013
The authors aimed to compare gesture use in infants with autism with gesture use in infants with other developmental disabilities (DD) or typical development (TD). Children with autism (n = 43), DD (n = 30), and TD (n = 36) were recruited at ages 2 to 7 years. Parents provided ...
Siu Wai-Kwan - - 2012
Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is one of the most common fatty acid oxidation defects that cause sudden unexpected deaths in infants. The death attributed to VLCAD deficiency can be prevented by early diagnosis with expanded newborn screening using tandem mass spectrometry. A favorable outcome can be achieved with ...
Anderson Sharon - - 2012
In the follow-up of New Jersey newborn screens suggestive of medium chain acyl-CoA dehydrogenase deficiency (MCADD) during a 30-month period, we identified five patients of Hispanic American ethnicity. With information provided by the New Jersey Department of Health and Human Services Newborn Screening program we calculated an overall cumulative incidence ...
Tollefson Megha M - - 2012
BACKGROUND AND OBJECTIVES:Infantile hemangiomas (IH) are recognized as growing rapidly during the first months of life, but details of early growth before 3 months of age have not been well-characterized. Our goal was to study early IH growth by using parental photographs of infant children with facial IHs to better ...
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