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Johnson Tricia J - - 2013
To determine the association between direct costs for the initial neonatal intensive care unit hospitalization and 4 potentially preventable morbidities in a retrospective cohort of very low birth weight (VLBW) infants (birth weight <1500 g). The sample included 425 VLBW infants born alive between July 2005 and June 2009 at ...
Kuo Patty X - - 2012
Few fMRI studies have investigated the brain-behavioral basis of parenting in human fathers. Ten fathers were videotaped and gave salivary testosterone samples while interacting with their 2-4 months old infants, and viewed video clips of their own infant and an unfamiliar age-, ethnicity- and sex-matched other infant during an fMRI ...
Briatore Eleonora - - 2012
Objective: EEG and MRI are useful tools to evaluate the severity of brain damage and to provide prognostic indications in asphyxiated neonates. Aim of our study is to analyze the relationship between serial neonatal EEGs and severity and sites of brain lesions on MRI in neonates undergoing hypothermia, following a ...
Alshammari Jaber - - 2012
Bilateral congenital vocal fold paralysis (BVFP) may result from multiple etiologies or remain idiopathic when no real cause can be identified. If obstructive dyspnea is significant and requires urgent stabilization of the airway, then intubation is performed first and an MRI of the brain is conducted to rule out an ...
Elsabbagh Mayada - - 2012
A popular idea related to early brain development in autism is that a lack of attention to, or interest in, social stimuli early in life interferes with the emergence of social brain networks mediating the typical development of socio-communicative skills. Compelling as it is, this developmental account has proved difficult ...
Venuti Paola - - 2012
This study used fMRI to measure brain activity during adult processing of cries of infants with autistic disorder (AD) compared to cries of typically developing (TD) infants. Using whole brain analysis, we found that cries of infants with AD compared to those of TD infants elicited enhanced activity in brain ...
Honda Noritsugu - - 2012
ObjectiveThe purpose of this study was to determine whether therapeutic touch in preterm infants can ameliorate their sensory punctate stimulus response in terms of brain activation measured by near-infrared spectroscopy.MethodsThe study included 10 preterm infants at 34-40&emsp14;weeks' corrected age. Oxyhaemoglobin (Oxy-Hb) concentration, heart rate (HR), arterial oxygen saturation (SaO(2)) and ...
Yamashita Wakayo - - 2012
In three-dimensional face recognition studies, it is well known that viewing rotating faces enhance face recognition. For infants, our previous study indicated that 8-month-old infants showed recognition of three-dimensional rotating faces with a direct gaze, and they did not learn with an averted gaze. This suggests that gaze direction may ...
Shankaran Seetha - - 2012
OBJECTIVE: The objective of our study was to examine the relationship between brain injury and outcome following neonatal hypoxic-ischaemic encephalopathy treated with hypothermia. DESIGN AND PATIENTS: Neonatal MRI scans were evaluated in the National Institute of Child Health and Human Development (NICHD) randomised controlled trial of whole-body hypothermia and each ...
Janvier Annie - - 2012
In this issue of the journal, Jason Baardness and Rebecca Pearce discuss their trying experience as the parents of 25 week twins ((1)) . Lily died after 7 days of NICU stay and Maren had a very complicated course. We took care of their two daughters. Like most parents, they ...
Choe Myong-Sun MS Fetal-Neonatal Neuroimaging and Developmental Science Center, Children's Hospital Boston, Boston, MA, - - 2013
Elucidation of infant brain development is a critically important goal given the enduring impact of these early processes on various domains including later cognition and language. Although infants' whole-brain growth rates have long been available, regional growth rates have not been reported systematically. Accordingly, relatively less is known about the ...
Atzil Shir - - 2012
Research on the neurobiology of parenting has defined biobehavioral synchrony, the coordination of biological and behavioral responses between parent and child, as a central process underpinning mammalian bond formation. Bi-parental rearing, typically observed in monogamous species, is similarly thought to draw on mechanisms of mother-father synchrony. We examined synchrony in ...
Merhar S L - - 2012
Objective:To describe the findings on fetal and postnatal magnetic resonance imaging (MRI) in premature infants with twin-twin transfusion syndrome (TTTS) and to determine whether currently used staging systems and other fetal and postnatal factors correlate with brain injury in this population.Study Design:We performed a prospective study of 22 premature infants ...
Jandó Gábor - - 2012
Although there is a great deal of knowledge regarding the phylo- and ontogenetic plasticity of the neocortex, the precise nature of environmental impact on the newborn human brain is still one of the most controversial issues of neuroscience. The leading model-system of experience-dependent brain development is binocular vision, also called ...
Vanderwert Ross E RE Human Development, University of Maryland, 3304Benjamin Building, College Park, MD 20742, USA. - - 2012
Brain electrical activity is one means of assessing neural development in awake, reactive infants. The development of the electroencephalogram (EEG) in the first week of infant rhesus macaque life is poorly understood though recent work has demonstrated the utility of using this measure to assess neural responses to biologically meaningful ...
Gousias Ioannis S IS Centre for the Developing Brain, Imperial College London, and MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK - - 2012
Premature birth is a major and growing problem. Investigations into neuroanatomical correlates and consequences of preterm birth are hampered by complex neonatal brain anatomy and unavailability of atlases and protocols covering the whole brain. We developed delineation protocols for the manual segmentation of cerebral magnetic resonance (MR) images from newborn ...
Grossmann Tobias - - 2012
Much research has been carried out to understand how human brains make sense of another agent in motion. Current views based on human adult and monkey studies assume a matching process in the motor system biased toward actions performed by conspecifics and present in the observer's motor repertoire. However, little ...
Kraybill Jessica H JH Department of Psychology, Virginia Tech, Blacksburg, VA 24061, USA. - - 2013
Little is known about factors that promote optimal development of executive function (EF) skills. The focus of this study was associations among early maternal behaviors, infant frontal brain electrical activity, and child EF at age 4 and following kindergarten. Infant frontal electroencephalogram was collected from 56 infants at 10 months ...
Key Alexandra P F - - 2012
The study examined whether 9-month-old infants at average vs. high risk for autism spectrum disorder (ASD) process facial features (eyes, mouth) differently and whether such differences are related to infants' social and communicative skills. Eye tracking and visual event-related potentials (ERPs) were recorded in 35 infants (20 average-risk typical infants, ...
Hazlett Heather Cody - - 2012
Individuals with autism as young as 2 years have been observed to have larger brains than healthy comparison subjects. Studies using head circumference suggest that brain enlargement is a postnatal event that occurs around the latter part of the first year. To the authors' knowledge, no previous brain imaging studies ...
Podraza Wojciech - - 2012
Abstract Objectives: The factors that influence the CNS development can affect either the retina or the brain cortex. Immaturity of the brain cortex reflects immaturity of the retina and vice versa. The immature retina is more vulnerable than the mature retina, and is therefore more likely to develop retinopathy of ...
Elliott Jane A - - 2012
AimsTo determine whether the brain-body weight ratio is increased in sudden infant death syndrome (SIDS).MethodsReview of autopsy files from Forensic Science SA, South Australia was undertaken over an eight-year period from 1999 to 2006, with classification of cases according to the San Diego definition. Sudden and/or unexpected deaths in previously ...
Slattery Justine - - 2012
Early sucking and swallowing problems may be potential markers of neonatal brain injury and assist in identifying those infants at increased risk of adverse outcomes, but the relation between early sucking and swallowing problems and neonatal brain injury has not been established. The aim of the review was, therefore, to ...
O'Reilly Deirdre - - 2012
OBJECTIVE: To assess the strength of association between alternative measures of electroencephalographic (EEG) signal peak-to-peak amplitude (ppA) and postmenstrual age (PMA) among a cohort of extremely premature infants. METHODS: 177 Two-channel EEG recordings 3-6h long were collected from 26 infants born before 29weeks of gestation. The raw EEG was converted ...
Kato Ikuko - - 2012
Low-frequency oscillations in cerebral blood flow that are suggestive of resting-state brain activity have recently been reported, but no study on the development of resting-state brain activity in preterm infants has been performed. The objective of this study was to measure the cerebral blood flow oscillations, which are assumed to ...
Wan Catherine Y - - 2012
Differences in brain structures between blind and sighted individuals have not been widely investigated. Furthermore, existing studies have included individuals who were blinded by retinopathy of prematurity, a condition that is associated with premature birth. Recent pediatric research has reported structural differences in individuals who were born prematurely, suggesting that ...
McMahon Erin - - 2012
Preterm infants in the neonatal intensive care unit (NICU) often close their eyes in response to bright lights, but they cannot close their ears in response to loud sounds. The sudden transition from the womb to the overly noisy world of the NICU increases the vulnerability of these high-risk newborns. ...
Trainor Laurel J - - 2012
Musical enculturation is a complex, multifaceted process that includes the development of perceptual processing specialized for the pitch and rhythmic structures of the musical system in the culture, understanding of esthetic and expressive norms, and learning the pragmatic uses of music in different social situations. Here, we summarize the results ...
Nakagawa Thomas A - - 2012
To review and revise the 1987 pediatric brain death guidelines. Relevant literature was reviewed. Recommendations were developed using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system. (1) Determination of brain death in term newborns, infants, and children is a clinical diagnosis based on the absence of neurologic function ...
Jary Sally - - 2012
Aim  To correlate volumetric magnetic resonance imaging at term with neurodevelopmental outcome at 2 years in infants with post-hemorrhagic ventricular dilatation. Preterm infants with post-hemorrhagic ventricular dilatation have high risk of disabilities but the range is wide and predicting severity of motor and mental disability is difficult. Methods  25 preterm ...
Ortinau Cynthia - - 2012
Infants with congenital heart disease (CHD) have delayed brain maturation and alterations in brain volume. Brain metrics is a simple measurement technique that can be used to evaluate brain growth. This study used brain metrics to test the hypothesis that alterations in brain size persist at 3 months of age ...
Collett Brent R BR Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. - - 2012
Infants with deformational plagiocephaly (DP) have been shown to exhibit developmental delays relative to unaffected infants. Although the mechanisms accounting for these delays are unknown, one hypothesis focuses on underlying differences in brain development. In this study, we used MRI to examine brain volume and shape in infants with and ...
Leijser Lara M - - 2012
BACKGROUND: The main causes of severe fetal anaemia are red-cell allo-immunization, parvo B19 virus infection and feto-maternal haemorrhage. Treatment consists of intrauterine transfusion (IUT). Neuro-imaging studies in surviving neonates treated with IUT are scarce. AIMS: To assess if neonates treated with IUT for fetal anaemia are at risk for cerebral ...
Schmitz Thomas - - 2012
In preterm infants, the risk to develop attention-deficit/hyperactivity disorder is 3 to 4-fold higher than in term infants. Moreover, preterm infants exhibit deficits in motor coordination and balance. Based on clinical data, higher oxygen levels in preterm infants lead to worse neurological outcome, and experimental hyperoxia causes wide-ranging cerebral changes ...
Kuipers Remko S - - 2012
INTRODUCTION: There are no data on the intrauterine fatty acid (FA) compositions of brain, liver and adipose tissue of infants born to women with high fish intakes. SUBJECTS AND METHODS: We analyzed the brain (n=18), liver (n=14) and adipose tissue (n=11) FA compositions of 20 stillborn infants with different gestational ...
Verney Catherine - - 2012
Disabilities after brain injury in very preterm infants have mainly been attributed to noncystic periventricular white matter injury (PWMI). We analyzed spatiotemporal patterns of PWMI in the brains of 18 very preterm infants (25-29 postconceptional weeks [pcw]), 7 preterm infants (30-34 pcw), and 10 preterm controls without PWMI. In very ...
Leonhardt Merçè - - 2012
BACKGROUND: Neonatal brain injuries are the main cause of visual deficit produced by damage to posterior visual pathways. While there are several studies of visual function in low-risk preterm infants or older children with brain injuries, research in children of early age is lacking. AIM: To assess several aspects of ...
Keunen K - - 2012
Abstract Objective: To evaluate the clinical value of neonatal brain tissue segmentation in preterm infants according to the literature. Methods: A structured literature search was undertaken in MEDLINE/Pubmed. This included all publications on volumetric brain tissue assessment in preterm infants at term-equivalent age (TEA) compared to brain tissue volumes of ...
Tam Emily W Y EW Department of Neurology, University of California San Francisco, San Francisco, CA, - - 2012
To investigate the contribution of hypoglycemia in the first 24 hours after birth to brain injury in term newborns at risk for neonatal encephalopathy. A prospective cohort of 94 term neonates born between 1994 and 2010 with early postnatal brain magnetic resonance imaging studies were analyzed for regions of brain ...
Als H - - 2012
The effect of NIDCAP (Newborn Individualized Developmental Care and Assessment Program) was examined on the neurobehavioral, electrophysiological and neurostructural development of preterm infants with severe intrauterine growth restriction (IUGR). A total of 30 infants, 27-33 weeks gestation, were randomized to control (C; N=17) or NIDCAP/experimental (E; N=13) care. Baseline health ...
Katano Hiroyuki - - 2012
Disproportionately large communicating fourth ventricle (DLCFV) is usually experienced in adults with no previous experience of shunting. We present a case of an infant with an enlarged fourth ventricle similar to isolated fourth ventricle (IFV) which appeared after shunting. The patient's brain stem symptoms and the abnormal appearance of the ...
Batalle Dafnis - - 2012
Intrauterine growth restriction (IUGR) due to placental insufficiency affects 5-10% of all pregnancies and it is associated with a wide range of short- and long-term neurodevelopmental disorders. Prediction of neurodevelopmental outcomes in IUGR is among the clinical challenges of modern fetal medicine and pediatrics. In recent years several studies have ...
Low Evonne - - 2012
ObjectiveTo investigate any possible effect of cooling on seizure burden, the authors quantified the recorded electrographic seizure burden based on multichannel video-EEG recordings in term neonates with hypoxic-ischaemic encephalopathy (HIE) who received cooling and in those who did not.Study designRetrospective observational study.PatientsNeonates >37 weeks gestation born between 2003 and 2010 ...
Panigrahy Ashok - - 2012
For typically developing infants, the last trimester of fetal development extending into the first post-natal months is a period of rapid brain development. Infants who are born premature face significant risk of brain injury (e.g., intraventricular or germinal matrix hemorrhage and periventricular leukomalacia) from complications in the perinatal period and ...
Alvarado-Ruiz Gerardo A - - 2012
Ultrasonography of cortical and cingulum maturity patterns, were studied in newborns and infants with congenital hypothyroidism (CH). Transversal study of 29 newborns and infants with CH, detected by neonatal screening and confirmed with thyroid function test, thyroid ultrasonography, and thyroid scintigraphy. During the first 2 months of life, transfontanelar brain ...
Abdel Raheem Moustafa M - - 2012
To assess brain development and brain injury in neonates with cyanotic and acyanotic congenital heart disease (CHD). The study included 52 term infants with CHD who were divided into two groups: Cyanotic (n=21) and acyanotic (n=31). Fifteen healthy neonates of matched age and sex were enrolled in the study as ...
Tymofiyeva Olga - - 2012
Defining the structural and functional connectivity of the human brain (the human "connectome") is a basic challenge in neuroscience. Recently, techniques for noninvasively characterizing structural connectivity networks in the adult brain have been developed using diffusion and high-resolution anatomic MRI. The purpose of this study was to establish a framework ...
Nag Deb Sanjay DS Tata Main Hospital, Jamshedpur, India. - - 2012
We report a case of a premature neonate born at 34 weeks and operated at 6 weeks of age developing unexplained seizures 10 hours after the end of surgery under single shot caudal epidural analgesia with bupivacaine and lidocaine combined with general anesthesia.
Montoya Jessica L JL Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of - - 2012
Infant cries and facial expressions influence social interactions and elicit caretaking behaviors from adults. Recent neuroimaging studies suggest that neural responses to infant stimuli involve brain regions that process rewards. However, these studies have yet to investigate individual differences in tendencies to engage or withdraw from motivationally relevant stimuli. To ...
Gunn Julia K - - 2011
BACKGROUND: Perioperative brain injury is common in infants undergoing cardiac surgery. Amplitude-integrated electroencephalography (aEEG) provides real-time neurologic monitoring and can identify seizures and abnormalities of background cerebral activity. We aimed to determine the incidence of perioperative electrical seizures, and to establish the background pattern of aEEG, in neonates undergoing Norwood-type ...
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