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Harabor Andrei A Section of Neonatology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada. - - 2014
To review umbilical venous catheter (UVC) placement in neonates who underwent targeted neonatal echocardiography (TNE) and to correlate catheter tip placement on TNE and anteroposterior thoracoabdominal radiography. We conducted a retrospective analysis of 51 neonates who had UVC positions assessed by TNE and radiography in a neonatal intensive care unit ...
Kim Yun Jung YJ Department of Linguistics,University of California,Los - - 2014
Within the first year of life, infants learn to segment words from fluent speech. Previous research has shown that infants at 0;7·5 can segment consonant-initial words, yet the ability to segment vowel-initial words does not emerge until the age of 1;1-1;4 (0;11 in some restricted cases). In five experiments, we ...
Fyfe Karinna L KL The Ritchie Centre, Monash Institute of Medical Research and Prince Henry's Institute and Monash University, Melbourne, Australia; Department of Paediatrics, Monash University, Melbourne, Australia; - - 2014
Prone sleeping is a major risk factor for sudden infant death syndrome (SIDS) and preterm infants are at significantly increased risk. In term infants, prone sleeping is associated with reduced mean arterial pressure (MAP) and cerebral tissue oxygenation index (TOI). However, little is known about the effects of sleeping position ...
Zhao Wei W Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China Department of Paediatric Pharmacology and Pharmacogenetics, Hôpital Robert Debré, APHP, Paris, France Clinical Investigation Center CIC1426, INSERM, Paris, France EA7323, Université Paris Diderot-Université Paris Descartes, Paris, - - 2014
Ciprofloxacin is used in neonates with suspected or documented Gram-negative serious infections. Currently, its use is off-label partly because of lack of pharmacokinetic studies. Within the FP7 EU project TINN (Treat Infection in NeoNates), our aim was to evaluate the population pharmacokinetics of ciprofloxacin in neonates and young infants < ...
Zhang Xiaolan X Institute of Environmental Pollution and Health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR - - 2014
To investigate the temporal trend of polybrominated diphenyl ethers (PBDEs) in breast milk and assess the risks to breast- and formula-fed infants, breast milk and infant formula samples were collected from Shanghai, China. The PBDE concentrations decreased from 14.8 to 4.85pmol/g lipid weight during 2006-2012, with a rate of decrease ...
Abe Noriko N The Japanese Red Cross Akita College of - - 2014
During childcare practices in early infants, parents' distress would be relieved if they could have more reliable, objective indicators suggesting that their infant actually hopes to sleep. Objective of this study was to explore the possibility of using distal-proximal skin temperature gradients (DPG) to predict sleep-onset latency of nighttime sleep ...
Varela Marta M Department of Biomedical Engineering, Division of Imaging Sciences, King's College London, London, UK; Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, London, - - 2014
To measure cerebral blood flow (CBF) using Look-Locker arterial spin labeling (ASL) in children under 1 year of age and to investigate the advantages of using subject-specific estimates of ASL model parameters in this population. Of 12 scanned infants, we successfully acquired CBF maps in 7 (postmenstrual age: 32 to ...
Mou Yi - - 2013
Researchers have long been interested in the emergence of transitive reasoning abilities (e.g., if A>B and B>C, then A>C). Preschool-aged children are found to make transitive inferences. Additionally, nonhuman animals demonstrate parallel abilities, pointing to evolutionary roots of transitive reasoning. The present research examines whether 16-month-old infants can make transitive ...
Hahr Jung Y - - 2013
Autism as we know it, is caused iatrogenically and occurs reportedly one in 88 live birth [3]. Now national survey pegs autism prevalence one in 50 school-age children and the incidence is rising much fast in recent years. The author is hypothesizing idiopathic autism is caused by feeding of infant ...
Levy Neil - - 2013
This paper is a response to Giubilini and Minerva's defence of infanticide. I argue that any account of moral worth or moral rights that depends on the intrinsic properties of individuals alone is committed to agreeing with Giubilini and Minerva that birth cannot by itself make a moral difference to ...
Awolaran O T - - 2013
Duplex collecting system is a congenital genitourinary anomaly commonly found incidentally. Our experience with a duplex system associated with giant hydroureter presenting as mobile abdominal swelling that was noticed from birth, constipation, and failure to thrive is described. Ultrasound and IVU did not assist in making the diagnosis, while a ...
Armstrong Elizabeth Mitchell - - 2013
In this column, Elizabeth Mitchell Armstrong provides expert commentary on the article "Supporting Healthy and Normal Physiologic Childbirth: A Consensus Statement by ACNM, MANA, and NACPM." The consensus statement on normal physiologic birth points the way to recenter social norms and expectations around birth.
Thompson Alecia A Albert Einstein College of Medicine, Bronx, NY, - - 2013
In a pilot study, we found that the NIRS measurements were highly variable and dramatically decreased or disappeared sporadically while monitoring gastro-intestinal (GI) StO(2) on preterm neonates. We hypothesized that the light absorption characteristics of different neonatal and infant stool types may be interfering with NIRS GI measurements. Meconium, transitional, ...
Eliason Sabrina H Y - - 2012
Background Outborn infants born at community hospitals and transported to tertiary neonatal intensive care units (NICUs) for treatment account for 20% of all tertiary NICU admissions in Canada. Little is known about variations in their outcomes. The Transport Risk Index of Physiologic Stability (TRIPS) is a validated score of neonatal ...
Jenke Andreas - - 2012
Background:The aim of this study was to analyse whether the mucosal innate immune response of extremely low birth weight (ELBW) infants might play a role in the development of necrotizing enterocolitis (NEC).Methods:Between 04/2008 and 12/2009 antimicrobial peptides were prospectively measured in fecal samples of ELBW infants. In cases requiring abdominal ...
Hickey Leah - - 2012
Probiotics are micro-organisms that confer health benefits on the host. Postulated mechanisms include: increasing resistance of the mucosal barrier to migration of bacteria and their toxins by strengthening intestinal cell junctions, modification of host response to microbial products, augmentation of immunoglobulin A mucosal responses, enhancement of enteral nutrition to inhibit ...
Benkoe Thomas - - 2012
The aim of this study was to test the predictive value of interleukin (IL) 8 in the assessment of intestinal involvement in necrotizing enterocolitis (NEC). Forty infants with surgically treated NEC were classified into 3 groups based on intestinal involvement during laparotomy: focal (n = 11), multifocal (n = 16), ...
Ismail Intan H - - 2012
To cite this article: Ismail IH, Oppedisano F, Joseph SJ, Boyle RJ, Licciardi PV, Robins-Browne RM, Tang MLK. Reduced gut microbial diversity in early life is associated with later development of eczema but not atopy in high-risk infants. Pediatr Allergy Immunol 2012: 00: ABSTRACT: Background:  Alterations in intestinal microflora have ...
Rousseau Clotilde - - 2012
Clostridium difficile has long been considered to be a nosocomial pathogen but has emerged in the community in recent years. During infancy, asymptomatic C. difficile colonization is common. However, knowledge of colonization determinants and strain characteristics is limited. We studied the dynamics of C. difficile colonization in healthy infants from ...
Däbritz Jan - - 2012
OBJECTIVE: To determine whether longitudinal measurements of fecal S100A12, a fecal marker of intestinal inflammation, can identify very low birth weight infants at risk for necrotizing enterocolitis (NEC). STUDY DESIGN: This prospective study included 145 preterm infants with birth weight <1500 g. Meconium and stool samples (n = 843) were collected prospectively ...
Somri Mostafa - - 2012
STUDY OBJECTIVE: To assess the rate of restoration of gastrointestinal (GI) function following combined spinal-epidural (CSE) anesthesia compared with general anesthesia in young infants undergoing elective intestinal surgery. DESIGN: Prospective, randomized, controlled study. SETTING: Operating room and neonatal intensive care unit of a university hospital. SUBJECTS: 50 young infants undergoing ...
de Montigny Francine - - 2012
Transition to parenthood has long been examined from the angle of mothers' experience. When looked at this transition through fathers' lens, fathers' involvement and perceived parental efficacy appear to be landmarks of this experience. This article examines a model of the relationships among father involvement, perceived parental efficacy, events related ...
Vallès Y - - 2012
Clin Microbiol Infect 2012; 18 (Suppl. 4): 21-26 ABSTRACT: The establishment of a balanced intestinal microbiota is essential for numerous aspects of human health, yet the microbial colonization of the gastrointestinal tract of infants is both complex and highly variable among individuals. In addition, the gastrointestinal tract microbiota is often ...
Kumagai Hideki - - 2012
Episodes of streaked rectal bleeding are not uncommon in exclusively breast-fed infants less than 6 months of age. Although this rectal bleeding is thought to be associated with food protein-induced proctocolitis, the pathomechanism still remains unclear. The aim of this study was to investigate the intestinal microbiota and secretory immunoglobulin ...
Mancini Nicasio - - 2012
We present 3 cases of pre-term low-weight infants with suspected necrotizing enterocolitis (NEC) (1 eventually recognized as a connatal CMV infection), microbiologically monitored using a molecular assay detecting bacterial and fungal DNA in blood. The detection of DNA from enteric pathogens in blood was interpreted as a sign of ongoing ...
Wu Shu-Fen - - 2012
The incidence of necrotizing enterocolitis (NEC) and mortality rate associated with this disease are not decreasing despite more than three decades of intensive research investigation and advances in neonatal intensive care. Although the etiology of NEC is not clearly elucidated, the most accepted hypothesis at present is that enteral feeding ...
Vanmarle Kristy - - 2012
Previous research has shown indirectly that infants may use two different mechanisms-an object tracking system and an analog magnitude mechanism-to represent small (<4) and large (⩾4) numbers of objects, respectively. The current study directly tested this hypothesis in an ordinal choice task by presenting 10- to 12-month-olds with a choice ...
Hallab J C - - 2012
OBJECTIVE: To further define patterns of colonising intestinal microflora in newborn infants utilising molecular methods. METHODS: Ten term and 5 preterm (<32 wk) infants born at the Royal Hospital for Women, Sydney, Australia were enrolled in the present study and followed for 6 mo post partum. Serial stools were collected, DNA was ...
Squires Robert H - - 2012
To characterize the natural history of intestinal failure (IF) among 14 pediatric centers during the intestinal transplantation era. The Pediatric Intestinal Failure Consortium performed a retrospective analysis of clinical and outcome data for a multicenter cohort of infants with IF. Entry criteria included infants <12 months receiving parenteral nutrition (PN) ...
Ozdemır R - - 2012
To evaluate the association between respiratory tract Ureaplasma urealyticum (Uu) colonization and development of retinopathy of prematurity (ROP) requiring treatment. The infants with birthweight (BW) ≤1250 g born in a third-level neonatal intensive care unit between March 2009 and May 2010 were prospectively identified. Nasopharyngeal swabs for Uu colonization were taken ...
Singh Sunita - - 2012
Background: Developing countries at tertiary referral centre. This study analysed the aetiology of colonic perforation (CP) in neonates and infants. Materials and Methods: Retrospective analyses of 60 CP cases (presented from May 2005 to May 2011) were done. Results: The mean age at presentation was 8.33 ± 0.11 days (range, ...
Donovan Sharon M - - 2012
The infant intestinal microbiota is shaped by genetics and environment, including the route of delivery and early dietary intake. Data from germ-free rodents and piglets support a critical role for the microbiota in regulating gastrointestinal and immune development. Human milk oligosaccharides (HMO) both directly and indirectly influence intestinal development by ...
Juang David - - 2012
Newborn intestinal obstructions are a common reason for admission to neonatal ICUs. The incidence is estimated to be approximately 1 in 2000 live births. There are 4 cardinal signs of intestinal obstruction in newborns: (1) maternal polyhydramnios, (2) bilious emesis, (3) failure to pass meconium in the first day of ...
Delaney Cassidy A - - 2012
We present a case of a 7-week-old infant who presented with nonspecific respiratory symptoms that quickly progressed to sudden cardiac arrest as a consequence of late-onset diaphragmatic hernia and intestinal strangulation. Unless discovered as an incidental finding, late-onset diaphragmatic hernia should be considered a surgical emergency.
Macdonald A - - 2012
A term infant with antenatal diagnosis of visceral heterotaxy presented on the third day of life with bilious vomiting and rectal bleeding. Abdominal radiograph (Figure 1) and upper gastrointestinal contrast study (Figure 2) demonstrated intestinal malrotation with suspicion of midgut volvulus. Findings were confirmed at laparotomy where a right-sided stomach ...
Bouzerzour Karima - - 2012
The first months of life correspond to a key period in human life where dramatic physiological changes (establishment of microbiota, development of the immune system, etc.) occur. In order to better control these changes it is necessary to understand the behaviour of food in the gastrointestinal tract of the newborn. ...
Sato Takako - - 2012
Transmesenteric hernias are internal hernias caused by a congenital defect in the mesentery. They are rare causes of intestinal obstruction, but most commonly affect the small bowel. We report an unexpected death of an infant with a bowel obstruction caused by a congenital mesenteric defect, which was undiagnosed despite visits ...
Guarino Alfredo - - 2012
Abstract Gut microbiota is a complex ecosystem based on a dynamic and mutual interaction with the host. In order to study the diversity of intestinal microflora, three approaches are most commonly used including gene targeting polymerase chain reaction (PCR), molecular fingerprinting techniques such as DGGE (denaturing gradient gel electrophoresis) and ...
Liao Yalin - - 2012
Postnatal modeling of the intestinal epithelium has long-term impacts on the healthy development of infants and relies largely on nutrient composition of the diet. Lactoferrin (Lf) is among the various human milk trophic factors that facilitate the infant intestinal adaptation. Hydrolysis of Lf is minimal at the prevailing postprandial pH ...
Prencipe Giusi - - 2012
OBJECTIVES:: To evaluate whether polymorphisms of the Mannose-Binding Lectin (MBL-2) gene and MBL serum levels on admission to Neonatal Intensive Care Unit (NICU) are associated with Necrotizing enterocolitis (NEC) in preterm infants and to verify MBL expression in NEC bowels. METHODS:: In this retrospective cohort study, 107 neonates (41 with ...
Bishay Mark - - 2012
Our aim was to determine incidence, severity, and outcome, as well as predisposing factors and underlying diagnoses, of intestinal failure-associated liver disease (IFALD) in surgical infants requiring long-term parenteral nutrition (PN). We retrospectively studied surgical infants receiving PN for at least 28 days for congenital or acquired intestinal anomalies over ...
Ghionzoli Marco - - 2012
The purpose of this study is to evaluate (1) the predictive value of fetal bowel dilatation (FBD) for intestinal atresia in gastroschisis and (2) the postnatal management and outcome of this condition. A retrospective review of all gastroschisis cases diagnosed in our fetal medicine unit between 1992 and 2010 and ...
Cilieborg Malene S - - 2012
Necrotizing enterocolitis (NEC) develops in 5-10% of preterm infants in association with enteral feeding and bacterial colonization. It remains unclear how diet and bacteria interact to protect or provoke the immature gastrointestinal tract. Understanding the factors that control bacterial colonization may provide the clue to prevent NEC, and studies in ...
Boykova Marina - - 2012
Research on the phenomenon of transition spans several decades. This article discusses the transition from hospital to home and the challenges parents of preterm infants experience during a neonatal intensive care unit stay and after discharge. The article explores the link between parental problems and rehospitalizations and the need for ...
Denison Stephanie - - 2012
In this chapter, we review empirical evidence in support of infants' ability to make rudimentary probabilistic inferences. A recent surge of research in cognitive developmental psychology examines whether human learners, from infancy through adulthood, reason in ways consistent with Bayesian inference. However, when exploring this question an important first step ...
Smith Birgitte - - 2012
Introduction:The pathophysiology of necrotizing enterocolitis (NEC) is multifactorial, and gastrointestinal bacteria are thought to play an important role. In this study, the role of microflora in the gastrointestinal tract of neonates with NEC was assessed by comparing cases with controls.Results:Of the 163 neonates, 21 developed NEC. The risk of NEC ...
Turroni Francesca - - 2012
The human gastrointestinal tract (GIT) represents one of the most densely populated microbial ecosystems studied to date. Although this microbial consortium has been recognized to have a crucial impact on human health, its precise composition is still subject to intense investigation. Among the GIT microbiota, bifidobacteria represent an important commensal ...
Pop Mihai - - 2012
Simultaneous analysis of the gut microbiome and host gene expression in infants reveals the impact of diet (breastfeeding versus formula) on host-microbiome interactions.
Madan J C - - 2012
Pulmonary damage caused by chronic colonization of the cystic fibrosis (CF) lung by microbial communities is the proximal cause of respiratory failure. While there has been an effort to document the microbiome of the CF lung in pediatric and adult patients, little is known regarding the developing microflora in infants. ...
Bozzetti Valentina - - 2012
IUGR infants are thought to have impaired gut function after birth, which may result in intestinal disturbances, ranging from temporary intolerance to the enteral feeding to full-blown NEC.In literature there is no consensus regarding the impact of enteral feeding on intestinal blood flow and hence regarding the best regimen and ...
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