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Hall J D - - 1985
All reported cases of infant botulism except one have been caused by proteolytic strains (group I) of Clostridium botulinum, toxin types A or B. We describe the cultural and biochemical characteristics of the causative organism of this singular case of infant botulism, caused by type F botulinal toxin. Although this ...
Dezfulian M - - 1985
A low molecular weight substance that induced seizures and death in mice was present in the stool of a child with infant botulism. This interfered with mouse bioassay used for detecting Clostridium botulinum toxin. After removal of the interfering substance by a prolonged dialysis with buffered saline, in vivo neutralization ...
Williams A J - - 1985
There is a linear relationship between potassium removal during haemodialysis and plasma potassium (Kp). Kp falls rapidly during the first hour of dialysis but very little during the last two hours of a five hour dialysis. There is a fairly constant movement of potassium from the intracellular to extracellular space ...
Rescorla F J - - 1984
Contemporary neonatal intensive care has resulted in survival of many seriously ill preterm and older infants that frequently present with symptomatic inguinal hernia. Controversy exists concerning timing and safety of early repair in prematures or other neonates, especially those hospitalized with concurrent illness. This study examines this topic by evaluating ...
Moazam F - - 1984
The results of this study of 134 patients confirm the increased incidence of previously unrecognized inguinal hernias after ventriculoperitoneal shunting procedures. Infants with intraventricular hemorrhage appeared to be the most susceptible, although associated prematurity may play an additional role. Close observation of infants and children who undergo ventriculoperitoneal shunting is ...
Roguin N - - 1984
Verapamil is a useful drug for treating supraventricular tachycardia; however, severe side effects occasionally have been reported in infants. We describe here our experience with the use of a 10 percent solution of intravenous calcium gluconate prior to the use of verapamil in infants with paroxysmal supraventricular tachycardia. In all ...
Pokorny W J - - 1984
Morgagni hernias during infancy are associated with significant respiratory symptoms as well as other congenital anomalies, particularly congenital heart disease. During the past 6 years we have had the opportunity to treat five infants less than 1 year of age with Morgagni hernias. A review of the literature revealed an ...
Tórtora J C - - 1984
A medium containing 0.50 g of thiotone peptone, 0.30 g of soluble starch, 0.02 g of MgSO4 X 7H2O, 0.90 g of Na2HPO4 X 2H2O, 100.00 ml of distilled water, and optionally , 166 micrograms of dichloridric thiamine supported sporulation of 138 out of 141 Clostridium perfringens strains. Comparatively this ...
Puri P - - 1984
In the years from 1971 to 1980 inclusive, 511 infants under 1 year of age presented with inguinal hernia. Of these, 158 (31%) (149 boys and 9 girls) had incarcerated inguinal hernia. In 151 (95.5%) infants the incarcerated inguinal hernia was reduced by taxis and herniotomy performed 48 to 72 ...
Morris J G JG - - 1983
Data were obtained for the 96 hospitalized cases of infant botulism reported to the Centers for Disease Control between 1976-1980 from all states other than California. Forty-one cases were associated with Clostridium botulinum type A, 53 with type B, one with type F, and one with a strain of C. ...
Libby J M - - 1983
C difficile produces two toxins, each of which is cytotoxic and lethal to animals [1]. Whether one or both of the toxins is responsible for pseudomembranous colitis in humans is unknown. C difficile is rarely found in the intestinal tracts of healthy adults, and then only in relatively low numbers. ...
Chinn D H - - 1983
Seven infants born at our institution between July 1979 and June 1982 had congenital diaphragmatic hernia (CDH). Four cases of CDH were correctly identified by fetal ultrasonography. Diagnosis relied upon the demonstration of abdominal organs within the thorax. During this period, no false positive diagnoses of CDH were made. Significant ...
Cornblath D R - - 1983
Infantile botulism is a recently recognized cause of acute hypotonic paresis and respiratory failure in young infants. Electrophysiological testing has proven useful in early diagnosis in suspected cases by demonstrating abnormal neuromuscular transmission as is known to occur in botulism. Twenty-five infants with bacteriologically proven botulism were studied by uniform ...
Le Coultre C - - 1983
From 1977 to 1981, 40 infants and children were operated for incarcerated inguinal hernia, 35 boys and 5 girls. During this time, 903 hernias were cured. Follow-up examination has been possible with 32 boys, from 6 months to 5 years after surgery. Three have an irreversible lesion of the testis ...
Donaldson M D - - 1983
A commercially available closed dialysis system and a new peritoneal cannula with potential advantages for infants have been developed. The dialysis set includes three dialysate bags that may be connected to the filling burette; the warming coil of the set is placed in a thermostatically controlled water bath. The peritoneal ...
Lacey S R - - 1983
Creation of a substitute hemidiaphragm for an infant born with agenesis of the hemidiaphragm is a formidable task. Subsequent growth of the infant may produce distortion or fracture of diaphragmatic prostheses. Our experience with a surviving two year old infant with agenesis led us to conclude that a Silastic prosthesis ...
Murrell W G - - 1983
The isolation of Clostridium botulinum from the home environment of New South Wales patients with infant botulism is reported. Of the three cases of infant botulism type B, the bacteria were isolated from soil around the dwelling in one, and from tank rainwater in another. In one case with type ...
Gilligan P H - - 1983
The mouse lethality test is the most sensitive method for confirming the diagnosis of infant botulism. Both Clostridium difficile and Clostridium botulinum produce heat-labile toxins which are lethal for mice and can be found in the feces of infants. These two toxins can be distinguished from one another in this ...
Paton J C - - 1983
A 7-week-old boy presented with symptoms and signs characteristic of infant botulism, and the diagnosis was confirmed by the detection of Clostridium botulinum type A organisms and toxin in the feces. The levels of organisms and toxin in the feces were measured throughout the 81-day period in hospital. The maximum ...
Mitamura H - - 1982
Conventionally raised suckling mice were given 10(7) spores of a strain of Clostridium botulinum type E. Most but not all infant mice aged 8 through 19 days at the time of administration died after developing symptoms typical of botulism. However, none of the infant mice challenged with the spores at ...
Ito S - - 1982
Specific antisera against somatostatin-28 were prepared by absorption of somatostatin-28 antisera with sepharose 4B-somatostatin-14. Indirect immunofluorescence techniques using somatostatin-14 antisera and specific antisera against somatostatin-28 were carried out to elucidate the time of occurrence of somatostatin-28 in the fetal pancreatic islets and to ascertain whether somatostatin-28 was present in the ...
Wilson R - - 1982
We reviewed the clinical features of 99 cases of infant botulism reported to the Centers for Disease Control from states other than California for the period 1976 to 1980. There were no toxin-specific differences in the distribution of ages at onset or sex of the cases. For 76 (76%) patients ...
Pereyra A J - - 1982
The present study supports the thesis that failures in urethral suspensory-type operations in women with anatomic stress urinary incontinence often are caused by pull-out of suspensory sutures attached to attenuated endopelvic fascia around the urethrovesical junction. Thickening of this fascia helps impede suture pull-out. Such thickening is facilitated by detaching ...
Paton J C - - 1982
A 4-month-old boy presented with symptoms and signs characteristic of infant botulism. Examination of feces revealed Clostridium botulinum type B and type B toxin. The numbers of C. botulinum and the amount of toxin in feces were measured throughout the 4-week period in hospital. The maximum numbers and amounts were ...
Pickett J B - - 1982
In 1976 physicians in California reported the presence of botulism in infancy. Over a period of a few days infants developed generalized weakness and lost autonomic functions. The severity of infant botulism has varied from feeding difficulties to paralysis. No toxin was found in the infants' food, but it was ...
Neubauer M - - 1981
A case of moderately severe botulism was diagnosed in a 4 weeks old white female. Clostridium botulinum toxin was identified repeatedly in the infant's faeces by means of the mouse protection assay. Clostridium botulinum was isolated in pure culture from faecal material. Both the organism and the toxin were type ...
Santos J I - - 1981
A child with infant botulism became apneic and died while receiving ampicillin and gentamicin therapy. As aminoglycosides have been implicated in the induction and/or exacerbation of neuromuscular blockade, we used an animal model to test the hypothesis that aminoglycosides potentiate neuromuscular blockade of botulinum toxin. In the range of aminoglycoside ...
McCarten K M - - 1981
Right diaphragmatic hernia should be considered when an infant with Group B streptococcal infection shows deterioration. Although the diaphragm appears normal at first, increased density is seen in the right lower lobe shortly thereafter, indicating pneumonia and/or irregular aeration. Pleural effusion may develop over the next few days. Characteristically, the ...
Bloss R S - - 1981
The incidence of death from congenital diaphragmatic hernia appears to be unchanged in recent years despite advances in resuscitation, transport, and ventilatory support. Bilateral lung hypoplasia and abnormal pulmonary vascular reactivity as developmental consequences of the defect appear to play a major role in the continued high mortality rate. Recent ...
Lorentz W B WB - - 1981
We have recently trained two sets of parents to perform home peritoneal dialysis on their infants with chronic renal failure. Chronic dialysis was initiated before the age of one year with a body weight of less than 10 kg. The infants were maintained on dialysis for 10 and 13 months ...
Smith W P WP - - 1981
Although numerous articles have appeared in the literature on chronic isodense subdural hematomas, acute isodense subdural hematomas have received little attention. An experimental model was developed that demonstrated that blood with reduced hemoglobin concentration, 8-10 g/dl, is isodense with the brain. Two anemic patients with acute isodense subdural hematomas are ...
L'Hommedieu C - - 1981
The clinical evaluation of nine patients with severe infant botulism revealed an identifiable progression of signs due to blockade of the cholinergic synapse similar to that described for competitive blocking agents. This predictable sequence reflects different "margins of safety" for muscles involved in repetitive activities, diaphragmatic function and movement of ...
Kiesewetter W B - - 1980
The decision for or against bilateral exploration in unilateral hernias in infants is necessitated by the high incidence of obscure anatomic hernias on the opposite side. On the basis of studies done in 400 pediatric patients (mostly under 2 years of age), we believe that unilateral repair of a known ...
Stevens D C - - 1980
There were 47 seriously-ill neonates with medical causes of respiratory distress and 10 infants with severe respiratory distress secondary to a congenital diaphragmatic hernia treated with tolazoline according to a strict protocol designed to manage persistent fetal circulation (PFC). Of the 47 infants, 28 (60%) had a positive response defined ...
Thompson J A - - 1980
Between 1977 and 1979, 12 cases of infant botulism were diagnosed in Utah, and 87 control patients (normal, nonbotulism neurologic disease, and nonbotulism systemic disease) were evaluated. Observations from these patients suggest an expanded clinical spectrum of infant botulism including asymptomatic carriers of organism; mild hypotonia and failure to thrive; ...
Howard J P - - 1980
Two instances of pertussis in infants are reported which were diagnosed in an outpatient clinic. Factors regarding the diagnosis and possible prevention or reduction of the severity of this illness are discussed.
Dezfulian M - - 1980
Isolates Clostridium botulinum from foodborne and infant botulism cases in the United States were compared on the basis of toxigenicity, cultural and biochemical characteristics, metabolic products, and susceptibility to antimicrobial agents. Seventy-eight strains, including 42 from foodborne and 36 from infant botulism sources, were examined. Cultures on anaerobic blood agar ...
McGregor D B - - 1980
Development of herniography as a diagnostic tool has reopened the question of whether the asymptomatic groin should be explored at the time of unilateral herniorrhaphy in infants. In an attempt to provide data toward the formulation of an answer, the authors review 32 yr of experience with 160 infant hernias. ...
Vicens E - - 1980
A case of fetal masculinization resulting from a Krukenberg tumor in a pregnant woman is reported in a newborn infant with a sexual ambiguity of the external genitals, of the feminine pseudohermaphrodite type. She also had an incarceration of both ovaries and tubes in a right inguinoscrotal hernia that was ...
Wilcke B W BW - - 1980
Infant botulism is an infectious form of a disease heretofore principally known as food-borne intoxication. Previous epidemiologic and laboratory studies have shown that infant botulism results from the ingestion of spores of Clostridium botulinum that subsequently germinate in the infant intestine and produce botulinal toxin. A quantitative study of the ...
Wolfe J A - - 1979
Botulism is a serious intoxication caused by ingestion of food containing preformed botulinus toxin and characterized by rapidly progressive bulbar paralysis, generalized weakness, and respiratory insufficiency. In 1976 a distinct clinical entity of infant botulism was recognized. The disease apparently results from intraintestinal toxin production which produces a defect in ...
Hatheway C L - - 1979
The recent development and evaluation of procedures for examination of fecal specimens for botulinal toxin and Clostridium botulinum have provided the means by which infant botulism can be recognized. The toxicity for mice of fecal extracts containing botulinal toxin can be neutralized with specific botulinal antitoxin. The presence of C. ...
Demetree J W - - 1979
An infant has a nevus unius lateris with the histopathologic condition of acantholytic dyskeratosis. Similar cases have, in the past, been classified as unilateral Darier's disease. Since it is now recognized that the pathologic changes of acantholytic dyskeratosis are not specific for a given disease entity, we believe the concept ...
Chin J - - 1979
In an effort to identify vehicles by which Clostridium botulinum spores might have reached the intestine of patients with infant botulism, 555 samples of foods, drugs, and environmental specimens were examined. Of the food items, C. botulinum was only found in nine of 90 (10%) honey specimens. Five patients had ...
Brown L W - - 1979
Clinical investigations of infants hospitalized with botulism demonstrate a remarkable uniformity of complaints and physical findings. Constipation precedes a course of progressive weakness and cranial nerve dysfunction. Examination reveals hypotonia, hyporeflexia, and a variable pattern of involvement of the motor cranial nerves. Initial laboratory investigations should include electrodiagnostic tests, because ...
Schiller C M - - 1979
An understanding of changes in the processes of absorption, detoxification, and intoxication in the intestine of infants, especially during the perinatal period, may aid in reaching an understanding of why the syndrome of infant botulism is restricted to the first six months of life. Some of the important metabolic changes ...
Bonventre P F - - 1979
Oral toxicity of botulinal toxin is manifested when the toxin is absorbed from one or more anatomic regions of the intestinal tract and reaches target neurons. Toxin is absorbed primarily in the small intestine, although in infants the large intestine may be a site of absorption. Nanogram amounts of toxin ...
Midura T F - - 1979
Infant botulism is the newly recognized form of the disease in which illness results from the production of toxin in the infant's intestines. Between the recognition of infant botulism as a distinct clinical entity in 1976 and the end of 1978, 50 cases were identified in California. The diagnosis of ...
Pappis C - - 1979
Persistent Müllerian duct structures were found in 3 male cryptorchid infants aged 10--12 mo, during correction of a unilateral inguinal hernia. Division of the vas degerens, hysterectomy and scrotal orchidopexy were carried out. The authors believe that in subjects with a persistent müllerian duct syndrome, surgical placement of the testes ...
Arnon S S - - 1979
Infant botulism results from the in vivo production of toxin by Clostridium botulinum after it has colonized the infant's gut. Epidemiologic and laboratory investigations of this recently recognized disease were undertaken to identify risk factors and routes by which C. botulinum spores might reach susceptible infants. Clostridium botulinum organisms, but ...
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