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Vallès Y - - 2012
Clin Microbiol Infect 2012; 18 (Suppl. 4): 21-26 ABSTRACT: The establishment of a balanced intestinal microbiota is essential for numerous aspects of human health, yet the microbial colonization of the gastrointestinal tract of infants is both complex and highly variable among individuals. In addition, the gastrointestinal tract microbiota is often ...
Kumagai Hideki - - 2012
Episodes of streaked rectal bleeding are not uncommon in exclusively breast-fed infants less than 6 months of age. Although this rectal bleeding is thought to be associated with food protein-induced proctocolitis, the pathomechanism still remains unclear. The aim of this study was to investigate the intestinal microbiota and secretory immunoglobulin ...
Mancini Nicasio - - 2012
We present 3 cases of pre-term low-weight infants with suspected necrotizing enterocolitis (NEC) (1 eventually recognized as a connatal CMV infection), microbiologically monitored using a molecular assay detecting bacterial and fungal DNA in blood. The detection of DNA from enteric pathogens in blood was interpreted as a sign of ongoing ...
Wu Shu-Fen - - 2012
The incidence of necrotizing enterocolitis (NEC) and mortality rate associated with this disease are not decreasing despite more than three decades of intensive research investigation and advances in neonatal intensive care. Although the etiology of NEC is not clearly elucidated, the most accepted hypothesis at present is that enteral feeding ...
Vanmarle Kristy - - 2012
Previous research has shown indirectly that infants may use two different mechanisms-an object tracking system and an analog magnitude mechanism-to represent small (<4) and large (⩾4) numbers of objects, respectively. The current study directly tested this hypothesis in an ordinal choice task by presenting 10- to 12-month-olds with a choice ...
Hallab J C - - 2012
OBJECTIVE: To further define patterns of colonising intestinal microflora in newborn infants utilising molecular methods. METHODS: Ten term and 5 preterm (<32 wk) infants born at the Royal Hospital for Women, Sydney, Australia were enrolled in the present study and followed for 6 mo post partum. Serial stools were collected, DNA was ...
Squires Robert H - - 2012
To characterize the natural history of intestinal failure (IF) among 14 pediatric centers during the intestinal transplantation era. The Pediatric Intestinal Failure Consortium performed a retrospective analysis of clinical and outcome data for a multicenter cohort of infants with IF. Entry criteria included infants <12 months receiving parenteral nutrition (PN) ...
Ozdemır R - - 2012
To evaluate the association between respiratory tract Ureaplasma urealyticum (Uu) colonization and development of retinopathy of prematurity (ROP) requiring treatment. The infants with birthweight (BW) ≤1250 g born in a third-level neonatal intensive care unit between March 2009 and May 2010 were prospectively identified. Nasopharyngeal swabs for Uu colonization were taken ...
Singh Sunita - - 2012
Background: Developing countries at tertiary referral centre. This study analysed the aetiology of colonic perforation (CP) in neonates and infants. Materials and Methods: Retrospective analyses of 60 CP cases (presented from May 2005 to May 2011) were done. Results: The mean age at presentation was 8.33 ± 0.11 days (range, ...
Donovan Sharon M - - 2012
The infant intestinal microbiota is shaped by genetics and environment, including the route of delivery and early dietary intake. Data from germ-free rodents and piglets support a critical role for the microbiota in regulating gastrointestinal and immune development. Human milk oligosaccharides (HMO) both directly and indirectly influence intestinal development by ...
Juang David - - 2012
Newborn intestinal obstructions are a common reason for admission to neonatal ICUs. The incidence is estimated to be approximately 1 in 2000 live births. There are 4 cardinal signs of intestinal obstruction in newborns: (1) maternal polyhydramnios, (2) bilious emesis, (3) failure to pass meconium in the first day of ...
Delaney Cassidy A - - 2012
We present a case of a 7-week-old infant who presented with nonspecific respiratory symptoms that quickly progressed to sudden cardiac arrest as a consequence of late-onset diaphragmatic hernia and intestinal strangulation. Unless discovered as an incidental finding, late-onset diaphragmatic hernia should be considered a surgical emergency.
Guarino Alfredo A Department of Pediatrics, University of Naples, Naples, Italy. - - 2012
To provide an update of the advantages of new-generation molecular diagnostics to study the diversity of intestinal microflora and to evaluate its alteration in human diseases. We review recent advances in understanding the complex ecosystem of gut microbiota based on a dynamic and mutual interaction with the host. In vaginal ...
Macdonald A - - 2012
A term infant with antenatal diagnosis of visceral heterotaxy presented on the third day of life with bilious vomiting and rectal bleeding. Abdominal radiograph (Figure 1) and upper gastrointestinal contrast study (Figure 2) demonstrated intestinal malrotation with suspicion of midgut volvulus. Findings were confirmed at laparotomy where a right-sided stomach ...
Bouzerzour Karima - - 2012
The first months of life correspond to a key period in human life where dramatic physiological changes (establishment of microbiota, development of the immune system, etc.) occur. In order to better control these changes it is necessary to understand the behaviour of food in the gastrointestinal tract of the newborn. ...
Sato Takako - - 2012
Transmesenteric hernias are internal hernias caused by a congenital defect in the mesentery. They are rare causes of intestinal obstruction, but most commonly affect the small bowel. We report an unexpected death of an infant with a bowel obstruction caused by a congenital mesenteric defect, which was undiagnosed despite visits ...
Liao Yalin - - 2012
Postnatal modeling of the intestinal epithelium has long-term impacts on the healthy development of infants and relies largely on nutrient composition of the diet. Lactoferrin (Lf) is among the various human milk trophic factors that facilitate the infant intestinal adaptation. Hydrolysis of Lf is minimal at the prevailing postprandial pH ...
Prencipe Giusi - - 2012
OBJECTIVES:: To evaluate whether polymorphisms of the Mannose-Binding Lectin (MBL-2) gene and MBL serum levels on admission to Neonatal Intensive Care Unit (NICU) are associated with Necrotizing enterocolitis (NEC) in preterm infants and to verify MBL expression in NEC bowels. METHODS:: In this retrospective cohort study, 107 neonates (41 with ...
Bishay Mark - - 2012
Our aim was to determine incidence, severity, and outcome, as well as predisposing factors and underlying diagnoses, of intestinal failure-associated liver disease (IFALD) in surgical infants requiring long-term parenteral nutrition (PN). We retrospectively studied surgical infants receiving PN for at least 28 days for congenital or acquired intestinal anomalies over ...
Ghionzoli Marco - - 2012
The purpose of this study is to evaluate (1) the predictive value of fetal bowel dilatation (FBD) for intestinal atresia in gastroschisis and (2) the postnatal management and outcome of this condition. A retrospective review of all gastroschisis cases diagnosed in our fetal medicine unit between 1992 and 2010 and ...
Cilieborg Malene S - - 2012
Necrotizing enterocolitis (NEC) develops in 5-10% of preterm infants in association with enteral feeding and bacterial colonization. It remains unclear how diet and bacteria interact to protect or provoke the immature gastrointestinal tract. Understanding the factors that control bacterial colonization may provide the clue to prevent NEC, and studies in ...
Boykova Marina - - 2012
Research on the phenomenon of transition spans several decades. This article discusses the transition from hospital to home and the challenges parents of preterm infants experience during a neonatal intensive care unit stay and after discharge. The article explores the link between parental problems and rehospitalizations and the need for ...
Denison Stephanie - - 2012
In this chapter, we review empirical evidence in support of infants' ability to make rudimentary probabilistic inferences. A recent surge of research in cognitive developmental psychology examines whether human learners, from infancy through adulthood, reason in ways consistent with Bayesian inference. However, when exploring this question an important first step ...
Smith Birgitte - - 2012
Introduction:The pathophysiology of necrotizing enterocolitis (NEC) is multifactorial, and gastrointestinal bacteria are thought to play an important role. In this study, the role of microflora in the gastrointestinal tract of neonates with NEC was assessed by comparing cases with controls.Results:Of the 163 neonates, 21 developed NEC. The risk of NEC ...
Turroni Francesca - - 2012
The human gastrointestinal tract (GIT) represents one of the most densely populated microbial ecosystems studied to date. Although this microbial consortium has been recognized to have a crucial impact on human health, its precise composition is still subject to intense investigation. Among the GIT microbiota, bifidobacteria represent an important commensal ...
Pop Mihai - - 2012
Simultaneous analysis of the gut microbiome and host gene expression in infants reveals the impact of diet (breastfeeding versus formula) on host-microbiome interactions.
Madan J C - - 2012
Pulmonary damage caused by chronic colonization of the cystic fibrosis (CF) lung by microbial communities is the proximal cause of respiratory failure. While there has been an effort to document the microbiome of the CF lung in pediatric and adult patients, little is known regarding the developing microflora in infants. ...
Bozzetti Valentina - - 2012
IUGR infants are thought to have impaired gut function after birth, which may result in intestinal disturbances, ranging from temporary intolerance to the enteral feeding to full-blown NEC.In literature there is no consensus regarding the impact of enteral feeding on intestinal blood flow and hence regarding the best regimen and ...
Hicks Penni D PD Rice University, Houston, TX, USA. - - 2012
1) To evaluate calcium absorption in infants fed a formula containing prebiotics (PF) and one without prebiotics (CF). 2) To compare calcium absorption from these formulas with a group of human milk-fed (HM) infants. A dual tracer stable isotope method was used to assess calcium absorption in infants exclusively fed ...
Liu Qian - - 2011
  Cronobacter sakazakii is an opportunistic pathogen associated with dry infant formula presenting a high risk to low birth weight neonates. The inactivation of C. sakazakii in dry infant formula by ultraviolet (UV) radiation alone and combined with hot water treatment at temperatures of 55, 60, and 65 °C were ...
Ingram Jennifer - - 2011
ObjectiveTo compare the effects of metoclopramide and domperidone on the breast milk output of mothers with infants in neonatal intensive care.DesignDouble-blind randomised controlled trial.SettingTertiary level neonatal intensive care unit (NICU).SampleEighty mothers expressing breast milk for their infants (mean gestational age 28 weeks) based in NICU and the amounts expressed fell ...
Daigavane P S - - 2011
Management of bilateral cleft lip and palate cases is a challenging task, and if the premaxilla is shifted to either side, it poses a problem for the surgeon to operate and also for the orthodontist to do the orthodontic alignment. The aim of this study was to reposition the shifted ...
Oztürk M Adnan - - 2011
Mucormycosis of the intestine is a rare fungal infection of childhood and is mostly encountered in neonates. It is a potentially lethal opportunistic fungal infection with rapid progression and high mortality in immunocompromised patients. The number of reported cases with intestinal mucormycosis is 19 to date. We herein report an ...
Joolay Y - - 2011
Necrotising enterocolitis (NEC) is an gastro-intestinal emergency occurring almost solely in preterm, low birth weight infants. Mortality, morbidity and the complication rate are high. An increase in NEC at the Groote Schuur Hospital nursery in 2008 prompted a change of practice, resulting in a significant decrease in the condition.
Sykes Joseph - - 2011
: To report a case of lobar emphysema in an infant who had a congenital diaphragmatic hernia that was surgically repaired at birth. : Case report. : Pediatric critical care unit in a tertiary care hospital. : A 9-month-old infant who had massive hyperinflation of the right lung and respiratory ...
Mohan Sowmya S - - 2011
Prematurity is one of the leading causes of infant morbidity and mortality globally. Over the years, however, advances in medicine and technology have enhanced the ability to care for babies at very early gestations. There has also been a shift in the distribution of births away from term/post-term gestations and ...
Castle Shannon L - - 2011
We present a case of a neonate with VACTERL-like association, with the VACTERL association defined as the non-random association of vertebral, anal, cardiac, esophageal, renal/kidney, and limb defects, as manifested by a hemivertebra, imperforate anus, and digit anomalies, in rare association with duodenal atresia and right-sided diaphragmatic hernia. This constellation ...
Berger Sarah E - - 2011
This research examined the development of handedness and footedness in infancy. We measured footedness by documenting the limb infants used to "lead-out" as they crawled or walked down a path several times. We measured handedness by documenting the hand infants used to reach for a goal at the end of ...
Di Nardo Matteo - - 2011
Purpose: Recent reports suggest that ultrasound-guided central venous cannulation may also be safe and effective in infants. This study aimed to evaluate the success and complications rate of this technique in infants weighing less than 5 kg. Methods: We studied 45 infants, weighing less than 5 kg (mean weight: 2.9 ...
Cheng I - - 2011
  Langerhans cell histiocytosis is a rare disease and is lethal in premature neonates. A male premature neonate born at gestational 33 weeks presented with generalized vesicles, hydrops fetalis with pleural effusion, bilateral cataracts, and severe respiratory distress syndrome complicated with persistent pulmonary hypertension. Skin biopsy confirmed the diagnosis of Langerhans ...
Nayak Dinesh M - - 2011
OBJECTIVE: To determine the composition of non pathogenic microflora (NPM) and pathogenic microflora (PM) and the assessment of factors affecting their colonization in the oropharynx. METHODS: Oropharyngeal swabs were obtained from 464 infants, aged 15 days to I year, with or without clinical signs and symptoms of upper respiratory tract infection ...
Haxhija Emir Q - - 2011
PURPOSE: Colonic atresia is a rare cause of congenital intestinal obstruction in the neonate. A review of the management and outcome of children with colonic atresia was performed. METHODS: A retrospective analysis of the complete records of children treated for colonic atresia during the 30-year period. RESULTS: A total of ...
Theyskens Claire - - 2011
Subcapsular rupture of the liver is a rare and usually lethal complication in preterm infants. A multidisciplinary approach is warranted to achieve the best possible outcome for these children.
Claas Marieke J - - 2011
Our objectives were to describe the obstetric complications of women who delivered an extremely low-birth-weight infant by comparing two consecutive 5-year periods and infants appropriate for gestational age (AGA) versus infants small for gestational age (SGA). This descriptive study included women ( N = 261) who delivered an infant ≤750 ...
Costner Brian J - - 2011
A case of a very low birthweight premature infant with a clinical presentation of necrotising enterocolitis that was found to have malrotation and midgut volvulus at autopsy is presented.
Hagmann C F - - 2011
Perinatal asphyxial encephalopathy occurs in 1 per 1000 live births and is associated with high mortality and morbidity. Therapeutic hypothermia increases intact survival and improves neurodevelopmental outcome in survivors. To evaluate (i) the opinion and practice of therapeutic hypothermia as a therapy for moderate to severe perinatal asphyxial encephalopathy amongst ...
El-Essawy Rania - - 2011
To determine the effectiveness and possible side effects of using propranolol for the treatment of orbital and periorbital infantile hemangiomas. Infants with periorbital or orbital hemangiomas who had not received either local or systemic corticosteroids were recruited. The changes in tumor size, color, and texture, and any side effects of ...
Rousseau Clotilde - - 2011
Clostridium difficile is a major enteric pathogen responsible for antibiotic-associated diarrhea. Host susceptibility to C. difficile infections results partly from inability of the intestinal microbiota to resist C. difficile colonization. During early infancy, asymptomatic colonization by C. difficile is common and the intestinal microbiota shows low complexity. Thus, we investigated ...
Alves Carla Ismirna Santos - - 2010
To describe the maturational development of 20 (aged 32-36 weeks) premature newborns (PNBs) without clinical or neurological complications from birth until term. The Saint-Anne Dargassies Scale was applied every two weeks until the age of 37 weeks. The PNBs showed normal Apgar and the growth in head circumference was adequate ...
May Meryta L A - - 2010
We report the first Australian case of treatment of infant botulism with a human botulinum antitoxin developed in the United States by the California Department of Public Health. Our patient's clinical improvement was rapid, and although the product is expensive, cost-analysis supports the economical viability of its use. In future ...
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