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Tymofiyeva Olga O Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States of - - 2013
Improved understanding of how the human brain is "wired" on a macroscale may now be possible due to the emerging field of MRI connectomics. However, mapping the rapidly developing infant brain networks poses challenges. In this study, we applied an automated template-free "baby connectome" framework using diffusion MRI to non-invasively ...
Laurent Heidemarie K HK Department of Psychology, University of Wyoming, Laramie, WY, USA. - - 2013
Depressed mothers show negatively biased responses to their infants' emotional bids, perhaps due to faulty processing of infant cues. This study is the first to examine depression-related differences in mothers' neural response to their own infant's emotion faces, considering both effects of perinatal depression history and current depressive symptoms. Primiparous ...
Sansom Jennifer K JK Developmental Neuromotor Control Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan 48109, USA. - - 2013
To characterize how infants with myelomeningocele (MMC) activate lower limb muscles over the first year of life, without practice, while stepping on a motorized treadmill. Twelve infants with MMC were tested longitudinally at 1, 6, and 12 months. Electromyography was used to collect data from the tibialis anterior, lateral gastrocnemius, ...
Saccani Raquel - - 2012
BACKGROUND: Whereas considerable work has been published regarding biological factors associated with infant health, much less is known about the associations of environmental context with infant development - the focus of the present cross-sectional study. METHODS: Data was collected on 561 infants, aged newborn to 18 months. Measures included the ...
Paulus Markus - - 2012
Recently, researchers have been debating whether infants' selective imitative learning is primarily based on sensorimotor processes (e.g., motor resonance through action perception) or whether inferential processes such as teleological reasoning (i.e., reasoning about the efficiency of others' actions) predominantly explain selective imitation in infancy. The current study directly investigated two ...
Harold Meredith Poore MP Department of Speech-Language-Hearing: Sciences and Disorders, 3001 Dole, 1000 Sunnyside Ave, University of Kansas, Lawrence, KS 66049, USA. - - 2013
The vocalizations and jaw kinematics of 30 infants aged 6-8 months were recorded using a Motion Analysis System and audiovisual technologies. This study represents the first attempt to determine the effect of play environment on infants' rate of vocalization and jaw movement. Four play conditions were compared: watching videos, social ...
Belfort Mandy B MB Division of Newborn Medicine, Children's Hospital Boston, Boston, MA, USA. - - 2013
Former preterm and very low birthweight infants require close neurodevelopmental surveillance after hospital discharge, but in-person professional testing is resource-intensive and inconvenient for families. A standardised developmental questionnaire completed by parents offers an alternative to in-person testing, but few such questionnaires have been validated. Our aim was to validate the ...
Reuner Gitta - - 2012
The study aims on comparing Bayley Scales of infant development third (Bayley-III) and Bayley second (Bayley-II) edition with special focus on patterns in the first year of life. Fifty-five premature infants (43 with low birth weight/LBW >1,499 g and 12 with very/extremely low birth weight/VLBW/ELBW <1,500 g) aged 7 months (corrected for prematurity) ...
Darrah Johanna - - 2012
AIM: To compare the order and age of emergence of rolling prone to supine and supine to prone before the introduction of back to sleep guidelines and 20years after their introduction. METHODS: The original normative data for the Alberta Infant Motor Scale (AIMS) were collected just prior to the introduction ...
Finkel Richard S - - 2012
A term infant, at familial risk for spinal muscular atrophy (SMA), had the diagnosis genetically confirmed on day 3 of life. Clinical evaluation, the CHOP INTEND motor scale and the CMAP amplitude were obtained on days 5 (pre-symptomatic), 20 (mildly weak), 34 (moderately weak) and 63 (severely weak). Palliative care ...
McCrory Cathal - - 2012
The present study examines whether breastfeeding is associated with neuro-developmental advantages at 9 months of age on a standardised measure of infant development in a large cohort study of Irish children. It is hypothesised that if breast-milk confers an independent benefit, infants who were never breastfed will have reached fewer ...
Tal Galit - - 2012
We evaluated the significance of head circumference growth velocity as related to developmental deficits during infancy. Head circumferences, lengths, and developmental diagnoses were retrieved in a standard manner at ≥2 time points from 437 infants with developmental deficits, and 3909 normally developing infants. Infants' ages ranged from 1-24 months, with ...
Szabó Nóra - - 2012
PURPOSE: Primary prevention by periconceptional folic acid supplementation can significantly reduce the risk of neural tube defects. EUROCAT, the European network of population-based registries for the epidemiologic surveillance of congenital anomalies, lacks sufficient data on the birth prevalence of neural tube defects in Hungary before and after the promotion of ...
Paulus Markus - - 2012
The present study examined the neural processes related to different forms of prosocial behavior in infancy by means of a longitudinal study. At 14months, infants' resting state brain activation asymmetries were assessed by means of EEG. At 18months, we examined infants' instrumental helping, and at 24months infants' behavior in a ...
Kahrs Björn A BA Department of Psychology, Tulane University, New Orleans, LA 70118, USA. - - 2013
The current study examines the developmental trajectory of banging movements and its implications for tool use development. Twenty (6- to 15-month-old) infants wore reflective markers while banging a handled cube; movements were recorded at 240 Hz. Results indicated that through the second half-year, banging movements undergo developmental changes making them ...
Bierton Christopher - - 2012
It has been suggested that the weather may promote some types of death; this study sought to determine if types of death in the region around Adelaide, South Australia, occur in non-random clusters and in relationship to the weather. A Poisson model was used to determine if the occurrence of ...
González González Nieves L - - 2012
Objective: To determine the effect of using customized vs. standard population birthweight curves to define large for gestational age (LGA) infants. Methods: We analyzed data obtained from 2,097 singleton pregnancies using three different methods of classifying newborn birthweight: standard population curves, British or Spanish customized curves. We recorded maternal characteristics, ...
Huusom Lene Drasbek - - 2012
Cerebral palsy consists of chronic and non-progressive clinical syndromes that are characterized by motor and postural dysfunction. In affected infants, voluntary movements become difficult and limited, and although clinical expression may change with time, this disability is accompanied with major personal and socioeconomic burdens. Preterm infants have an increased risk ...
Laurent Heidemarie K HK University of Wyoming, United States. - - 2012
This study addresses a gap in the attachment literature by investigating maternal neural response to cry related to infant attachment classifications and behaviors. Twenty-two primiparous mothers and their 18-month old infants completed the Strange Situation (SS) procedure to elicit attachment behaviors. During a separate functional MRI session, mothers were exposed ...
Bhat A N AN Physical Therapy Program, Department of Kinesiology, University of Connecticut, United - - 2012
Motor delays have been reported in retrospective studies of young infants who later develop Autism Spectrum Disorders (ASDs). In this study, we prospectively compared the gross motor development of a cohort at risk for ASDs; infant siblings of children with ASDs (AU sibs) to low risk typically developing (LR) infants. ...
Bejjani Charbel - - 2012
Sudden infant death syndrome (SIDS) remains the commonest cause of death in the post-neonatal period in the developed world. A leading hypothesis is that an abnormality in the brainstem of infants who succumb to SIDS, either causes or predisposes to failure to respond appropriately to an exogenous stressor. Neuronal apoptosis ...
Liu Yan-Lin - - 2013
Poor oral-motor developments in premature infants are common. From the viewpoint of developmental care, most of the infants required individualized therapy. The specific aim of our study was to evaluate the effectiveness and impact of early intervention of oral-motor management on feeding pattern and the neonatal outcomes in premature neonates. ...
Grossmann Tobias - - 2012
Integrating the multisensory features of talking faces is critical to learning and extracting coherent meaning from social signals. While we know much about the development of these capacities at the behavioral level, we know very little about the underlying neural processes. One prominent behavioral milestone of these capacities is the ...
Cole Whitney G - - 2012
In light of cross-cultural and experimental research highlighting effects of childrearing practices on infant motor skill, we asked whether wearing diapers, a seemingly innocuous childrearing practice, affects infant walking. Diapers introduce bulk between the legs, potentially exacerbating infants' poor balance and wide stance. We show that walking is adversely affected ...
Majid Aziz - - 2012
Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a clinically heterogeneous disorder linked to mutations in the immunoglobulin mu-binding protein 2 (IGHMBP2) gene on chromosome 11q13-q21. Most infants with SMARD1 present between six weeks and six months of age with respiratory distress secondary to diaphragmatic weakness and progressive ...
Ramírez-Altamirano María de Jesús Mde - - 2012
The purpose of this study was to identify the relationship of neurotoxic inorganic elements in the hair of patients with the diagnosis of Neural Tube Defects. Our initial hypothesis was that neurotoxic inorganic elements were associated with Neural Tube Defects. Twenty-three samples of hair from newborns were obtained from the ...
Cacchione Trix - - 2012
Research on object cognition in infancy suggests that children from (at latest) 1 year of age are capable of individuating objects according to property/kind information. It remains unclear from previous work, however, whether infants in such studies truly apply sortal (kind) concepts or whether they merely track objects on the ...
Ball Gareth G Centre for the Developing Brain, Division of Imaging Sciences & Biomedical Engineering, King's College London, London, - - 2013
Defining connectivity in the human brain signifies a major neuroscientific goal. Advanced imaging techniques have enabled the non-invasive tracing of brain networks to define the human connectome on a millimetre-scale. During early development, the brain undergoes significant changes that are likely represented in the developing connectome, and preterm birth represents ...
Zwanenburg Alex - - 2012
Electroencephalographic characteristics are useful in assessment of the functional status of specific neuronal connections relative to postmenstrual age. Interhemispheric burst synchrony (IBS) is a measure of the functional connectivity between the hemispheres in the maturing preterm brain.
Cogo P E - - 2012
Pulmonary hypoplasia and hypertension account for significant morbidity and mortality in neonates with congenital diaphragmatic hernia (CDH). Whether CDH is associated with surfactant dysfunction remains controversial. Therefore, we measure disaturated phosphatidylcholine and surfactant protein B concentration in tracheal aspirates and their synthesis rate in infants with CDH compared to infants ...
Dargaville Peter A - - 2012
ObjectiveTo evaluate the applicability and potential effectiveness of a technique of minimally-invasive surfactant therapy (MIST) in preterm infants on continuous positive airway pressure (CPAP).MethodsAn open feasibility study of MIST was conducted at two sites. Infants were eligible for MIST if needing CPAP pressure ≥7 cm H(2)O and FiO(2) ≥0.3 (25-28 ...
Bersani Iliana - - 2012
Immaturity of the pulmonary and immune systems represents an important risk factor for increased morbidity and mortality in neonates. Surfactant protein (SP)-A and SP-D, linking molecules between these two systems, are critical for lung homeostasis as they regulate surfactant metabolism and host immunodefense activities in innate and adaptive immunity. Preterm ...
Carlo W A - - 2012
Many neonates have respiratory disorders requiring oxygen supplementation and respiratory support. Even though advances in respiratory care such as surfactant and new ventilatory techniques have improved outcomes, mortality from respiratory failure and morbidities such as bronchopulmonary dysplasia are still common. In the trials of prophylactic, early, or late surfactant, the ...
Bohlin Kajsa - - 2012
There is mounting evidence that early continuous positive airway pressure (CPAP) from birth is feasible and safe even in very preterm infants. However, many infants will develop respiratory distress syndrome (RDS) and require surfactant treatment. Combining a non-invasive ventilation approach with a strategy for surfactant administration is important, but questions ...
Shangle Carl E - - 2012
OBJECTIVE: To evaluate the effects of surfactant administration on the neonatal brain using 3-channel neonatal electroencephalography (EEG). STUDY DESIGN: A prospective cohort of 30 infants had scalp electrodes placed to record brain waves using 3-channel EEG (Fp1-O1, C3-C4, and Fp2-O2). Sixty-second EEG epochs were collected from a 10-minute medication-free baseline, during ...
Alphonse Rajesh - - 2012
Continuous improvements in perinatal care have allowed the survival of ever more premature infants, making the task of protecting the extremely immature lung from injury, increasingly challenging. Premature infants at risk of developing chronic lung disease or bronchopulmonary dysplasia (BPD) are now born at the late canalicular stage of lung ...
Saxena Ashok - - 2012
OBJECTIVE: To analyze the outcome of inborn preterm neonates with respiratory-distress-syndrome(RDS), using the approach of administering nasal-continuous-positive-airway-pressure(CPAP) alone and administering surfactant only if they require mechanical ventilation(MV). METHODS: All preterm neonates diagnosed as RDS from 01-May-2006 to 10-July-2010 were prospectively enrolled for the study at a referral centre in India. ...
Tapia Jose L - - 2012
OBJECTIVE: To determine whether very low birth weight infants (VLBWIs), initially supported with continuous positive airway pressure (CPAP) and then selectively treated with the INSURE (intubation, surfactant, and extubation to CPAP; CPAP/INSURE) protocol, need less mechanical ventilation than those supported with supplemental oxygen, surfactant, and mechanical ventilation if required (Oxygen/mechanical ...
Sveinsdottir Snjolaug - - 2012
Cerebral intraventricular haemorrhage (IVH) is the most common cause of severe neurologic impairment following preterm birth in human infants. Ideally, an animal model for cerebral IVH should allow for reliable noninvasive evaluation of haemorrhagic extension and of subsequent development of posthaemorrhagic ventricular dilatation (PHVD). The aim of this study was ...
Wang Huanhuan - - 2012
OBJECTIVES: We retrospectively investigated incidence, morbidity, and mortality of neonatal respiratory failure (NRF) in China, with special emphasis on surfactant treated very immature infants. METHODS: NRF was defined as respiratory hypoxemia requiring mechanical ventilation and/or nasal continuous positive airway pressure for at least 24 hours. RESULTS: There were 6864 cases ...
Philip Alistair G S - - 2012
When bronchopulmonary dysplasia (BPD) was first described in 1967, the use of assisted ventilation in neonates was in its infancy. High concentrations of oxygen were implicated, and BPD was equated with 'pulmonary oxygen toxicity'. The etiologic role of not only oxygen but also peak inspiratory pressures and the duration of ...
Prendergast Michael - - 2012
Infants with congenital diaphragmatic hernia (CDH) or anterior wall defects (AWD) can suffer abnormal antenatal lung growth, the risk, however, may be greater for CDH infants. The objectives of this study were to test the hypothesis that following surgical correction, CDH infants would have worse lung function at follow-up than ...
Lista G - - 2012
Abstract Most preterm babies with a gestational age less than 23-27 wks need a respiratory support in the delivery room; the aim of ventilation is to create and maintain a functional residual capacity; to facilitate gas exchange and to minimize acute lung injury. The application of a continuous positive airway ...
Kotecha Sarah J - - 2012
In recent years, the rate of preterm births has risen in many industrialised countries with late preterm births forming a substantial proportion of the preterm births. Late preterm infants are delivered at the immature saccular stage of lung development when surfactant and antioxidant systems are still developing. It is now ...
Arias-Martínez Joel - - 2012
Background/Aims: Clara cell protein (cc-10) has been shown to negatively regulate inflammation, protect pulmonary surfactant from degradation in the lung, and administration of this recombinant protein improves the condition of infant respiratory distress syndrome (iRDS), a disease that occurred mainly in preterm infants. In view of the possibility that altered ...
Nakahara Hiromichi - - 2012
Lung surfactants (LS), a complex of ∼90 wt% lipids (mainly dipalmitoylphosphatidylcholine or DPPC) and ∼10 wt% surfactant proteins (SP-A, -B, -C, and -D), adsorb to an air-alveolar fluid interface and then lower its surface tension down to near zero during expiration. Intratracheal instillation of exogenous LS preparations can effectively compensate ...
Abdulla C O - - 2012
An apparently well baby girl born at term was presented with signs and symptoms suggestive of acute onset of generalised floppiness at the age of 3 months. Clinically, the baby had lower motor neuron type of muscle weakness; detailed investigation lead to the diagnosis of neuromuscular junction disorder secondary to ...
Eickmann Sophie Helena - - 2012
The immaturity of preterm infants' organ systems may lead to difficulties in adapting to different environmental stimuli. The aim was to compare the psychomotor development of preterm infants (with corrected age) and term infants aged 6 to 12 months and to investigate associated factors. Cross-sectional analytical study conducted at Hospital ...
Landi Nicole - - 2012
[This corrects the article on p. 32 in vol. 2, PMID: 21720537.].
Rojas-Reyes Maria Ximena - - 2012
Surfactant therapy is effective in improving the outcome of very preterm infants. Trials have studied a wide variety of surfactant preparations used either to prevent or treat respiratory distress syndrome (RDS). In animal models, prophylactic surfactant leads to more homogeneous distribution and less evidence of lung damage. However, administration requires ...
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