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Nowak-Göttl U U Pediatric Hematology and Oncology, University Hospital Münster, D-48149 Münster, Germany. - - 2001
To evaluate the role of plasminogen activator inhibitor-1 (PAI-1) and tissue-type plasminogen activator (t-PA) in children with an estimated risk of vascular occlusion reported to range from 7% to 16%, we conducted a prospective study in infants and children with underlying cardiac disease. One hundred and twenty-five children (neonate - ...
Takahashi M - - 2001
We describe the successful management of thoracoscopic thoracic duct ligation in a 2.5-kg compromised infant by using selective lobar-bronchial blockade. The technique reduces the risk of intraprocedural physiologic impairment, allowing the benefits of otherwise minimally invasive thoracoscopic procedures, even when the conditions of children are severely compromised.
Curry J I - - 2001
Erythromycin has been used as an antibiotic for more than four decades, but only in the last 10 years have other therapeutic benefits of this agent been exploited. Animal and human studies have demonstrated a prokinetic effect on the gastrointestinal tract at sub-antimicrobial doses (typically a quarter or less of ...
Kamimura M - - 2001
The presence of mucosa-associated lymphoid tissue (MALT) was investigated histopathologically in every 20th section from 99 vertically cut, celloidin-embedded temporal bone-eustachian tube (ET) specimens. Among specimens from infants and children between 1 month and 7 years of age, MALT was found in 22 of 44 (50%). However, in 26 adults ...
Arana A - - 2001
BACKGROUND: Paracetamol (N-acetyl-p-amino-phenol) or acetaminophen has become the most widely used analgesic and antipyretic in children. However, there is a wide discrepancy between the extent to which paracetamol is used and the limited available pharmacological data in small infants. The purpose of this article is to present a review of ...
Bavdekar S B - - 2001
Adrenocortical carcinoma in children is a rare tumor of adrenal gland. An infant presented with signs of virilization due to selective testosterone hypersecretion. Diagnosis was established with the help of the computerized tomographic scan and histopathological examination. Following adrenalectomy patient made uneventful recovery and six months later does not have ...
Vandenplas Y - - 2001
As gastro-oesophageal reflux disease (GORD) in infants and children is a motility disorder which differs in pathophysiology and clinical course from GORD in adults, prokinetics should be considered the drug of choice in certain circumstances. Indeed, cisapride may result in improvement of feeding tolerance in premature infants. Cisapride has a ...
Latifi S - - 2000
Inotropic agents are drugs which increase the stroke work of the heart at a given pre-load and after-load. All of these agents work through a final common pathway involving the modulation of calcium interactions with various myocardial contractile proteins. The agents employed with pediatric patients include the cardial glycosides, catecholamine ...
Taivainen T - - 2000
We studied the neuromuscular and cardiovascular effects of a single, rapidly administered intravenous dose of cisatracurium 0.15 mg.kg(-1) in 27 infants (aged 1-23 months) and 24 children (aged 2-12.5 years). After midazolam premedication, anaesthesia was induced and maintained with thiopental and alfentanil in addition to nitrous oxide in oxygen. Neuromuscular ...
Van Den Driessche M - - 2000
BACKGROUND: The lactose-[13C]ureide breath test (LUBT) is a novel, noninvasive test to determine orocecal transit time. Lactose ureide resists the action of brush border enzymes and is metabolized by colonic bacteria. The purpose of the present study was to adapt this breath test for children of various age groups and ...
Castro M - - 2000
Salivary cortisol is an index of plasma free cortisol and is obtained by a noninvasive procedure. We have been using salivary cortisol as a tool for physiological and diagnostic studies, among them the emergence of circadian rhythm in preterm and term infants. The salivary cortisol circadian rhythm in term and ...
Batmaz G - - 2000
Rhabdomyomas are the most common primary cardiac tumors in childhood, and are often associated with tuberous sclerosis. We report a huge rhabdomyoma in an asymptomatic four hour old infant who presented initially with a murmur due to moderate subaortic stenosis. Followup showed regression of the tumour. Although the indications for ...
Mori K - - 2000
BACKGROUND: Significant changes in the contractility and histologic structure of the ventricular myocardium occur during the early neonatal period. Cyclic variation (CV) of ultrasonic integrated backscatter (IBS) reflects myocardial contractile performance. The aim of this study was to define normal values of and its serial changes in CV of IBS ...
Altura R A - - 2000
Idiopathic myelofibrosis can develop in children as well as adults. However, the disease appears to be much more aggressive in adults, being characterized by poor survival rates and a high frequency of malignant transformation. Here, we describe three cases of idiopathic myelofibrosis in infants, two of whom were followed for ...
Case CL - - 2000
The issue of the proper use of radiofrequency catheter ablation in infants and small children is controversial. Rarely, catheter ablation techniques are indicated to cure malignant arrhythmias in the pediatric population. Indications, techniques, complications and success rates are reviewed.
Hildingsson U - - 2000
In previous studies, we observed that lactate concentrations in interstitial white adipose tissue are higher in small infants than in adults. Moreover, no lipolysis following catecholamine challenge has been reported in neonates and small infants. Our aim was to determine with microdialysis whether the above mentioned age-dependent changes could be ...
Newman L A - - 2000
The pediatric population with dysphagia is diverse, ranging from premature infants to fully grown adolescents. A variety of medical conditions cause swallowing disorders in pediatric patients. Complications of swallowing disorders can have severe and even fatal consequences. Swallowing disorders have a direct impact on nutrition, and adequate nutrition is required ...
de Boer A W - - 1999
OBJECTIVES: To study longitudinal changes in transcapillary ultrafiltration (TCUF) and marker clearance (MC), as a reflection of lymphatic absorption, in children on peritoneal dialysis (PD). To present data on fluid kinetics in infants younger than 2.5 years, using an intraperitoneal volume of 1200 mL/m2 body surface area (BSA). DESIGN: The ...
Davis S - - 1999
In older children and adults, density dependence (DD) of forced expiratory flow is present over the majority of the full flow-volume curve. In healthy subjects, DD occurs because the pressure drop from peripheral to central airways is primarily dependent on turbulence and convective acceleration rather than laminar resistance; however, an ...
Farrow S C - - 1999
It is hypothesized that higher indoor nitrogen dioxide levels cause diarrhoea in infants and that this is the result of a direct action of oxides of nitrogen on the gut. This hypothesis is tested by reviewing the reported association between methaemoglobin and diarrhoea in children and two recent reports on ...
McCollough M - - 1999
[McCollough M: Progress toward eliminating Haemophilus influenzae type b disease among infants and children-United States, 1987-1997 [commentary]. Ann Emerg Med July 1999;34:110-111.]
Bryan R T - - 1999
Primary sternal osteomyelitis in infants, older children, and adults is rare. Secondary sternal osteomyelitis, however, is more common because of the increased frequency of cardiothoracic surgery and intravenous drug abuse. Primary sternal osteomyelitis is reviewed, two infants with further cases of primary sternal osteomyelitis are presented, and diagnosis and management ...
Broadman L M - - 1999
The first steps to liberalize NPO guidelines began in the early 1980s and were based more on compassion than science. Infants were allowed to be awakened at 0300 and given clear liquids. Children whose anticipated surgical start times were later than 1200 were allowed to consume clear liquids at 0500. ...
Pieters R - - 1998
The prognosis of infant ALL, characterized by a high incidence of the immature CD10 negative B-lineage ALL (proB ALL) is poor. This study aimed to determine the resistance profile of infant ALL cells. In vitro drug resistance was determined by the MTT assay of 395 children with ALL at initial ...
Kertesz NJ - - 1998
In recent years, there have been new insights into the natural history of and the mechanisms responsible for supraventricular tachycardia in infants and children. Coupled with the advances in antiarrhythmic therapy and the development of radiofrequency ablation, there are now many therapeutic options for supraventricular tachycardia. This article provides an ...
Bruun C F - - 1998
Two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) was used to analyze C-reactive - (CRP) and serum amyloid A protein (SAA) in infants and children. Five SAA isotypes were identified. CRP showed vertical streaking, and its optical density values correlated with immunoturbidimetric measurements. As evaluated by densitometry, both proteins showed an age-dependent ...
Levine A - - 1998
OBJECTIVES: Life-threatening arrhythmias and prolonged QT interval have been reported in adults and children using cisapride, a medication structurally similar to procainamide. Premature infants have reduced activity of cytochrome p-450, the system responsible for metabolism of cisapride, which could lead to QT prolongation. Therefore, we prospectively studied premature infants and ...
Alter S J - - 1997
OBJECTIVE: To document the number of infants with spontaneous pneumothorax (SP) and determine the association of any underlying pathologic processes in the lung with SP. DESIGN: Retrospective chart review of infants admitted with SP from January 1985, to December 1994. SETTING: Patients admitted to The Children's Medical Center, Dayton, Ohio. ...
Uckun F M - - 1997
Leukemic cells from most patients with B-lineage acute lymphoblastic leukemia (ALL) appear to originate from normal B-lymphocyte precursors. The earliest B-cell progenitors coexpress the antigens CD10, CD19, or CD34 on their cell surfaces. In a large cohort of 2028 children with ALL, we compared treatment outcomes of a subset of ...
Amin M R - - 1997
We have observed 5 infants who demonstrate normal breathing when awake, but develop stridor while asleep. Flexible laryngoscopy in the awake state reveals either a normal larynx or redundancy of the aryepiglottic folds or arytenoid soft tissue without prolapse into the laryngeal inlet. When these children are sedated, however, the ...
Imamura E - - 1997
The prepuce and glans was examined in 4521 healthy infants and young children with a birthweight over 2600 g. There were 3238 infants aged 1-12 months and 1283 children aged 3 years. There is no custom of circumcision in Japan. The term phimosis implies the adhesion of the prepuce and ...
Reid M M - - 1997
Central review of bone marrow trephine biopsies obtained between January 1990 and July 1996 from 282 children with neuroblastoma showed that 18% of cores from older children and an unacceptably high 36% from infants were inadequate (p = 0.0002). Centres should choose their operators for this invasive investigation of infants ...
Cetta F - - 1997
We describe the diagnostic utility of adenosine infusion in an infant with chaotic atrial tachycardia. Transient blockade of the atrioventricular node during adenosine infusion added diagnostic certainty to the emergency department evaluation of this patient. Appropriate therapy for chaotic atrial tachycardia is controversial, so it is essential to differentiate this ...
Ng PC - - 1997
Two cases of ileal perforation in preterm infants treated with high-dose dexamethasone for bronchopulmonary dysplasia are described. Corticosteroid-induced gastroduodenal haemorrhage or perforation has been well documented, but less known to most clinicians is that the lower gastrointestinal tract can also be involved. Unlike previous reported cases in which affected infants ...
Nichols B L - - 1997
BACKGROUND & AIMS: Many malnourished infants have reduced lactase specific activity in the small intestine. The aim of this study was to test the hypothesis that the hypolactasia of malnourished infants results from transcriptional suppression of lactase expression. METHODS: Biopsy specimens were studied from two groups of infants: 29 with ...
Messineo A - - 1997
Acquired tracheobronchial strictures in infants are associated with significant morbidity. Their treatment requires different types of therapeutic procedures depending on the severity and location of the stenosis. We successfully dilated five children (ages between 1 and 23 months) with acquired tracheobronchial (stenoses two carinal and three of the mainstem bronchi) ...
Kart T - - 1997
The English language literature has been reviewed in order to evaluate the present knowledge on morphine's metabolism and pharmacokinetics in children. The majority of preterm neonates are capable of glucuronidating morphine, but birth weight; gestational and postnatal age influence the glucuronidation capability. Term neonates, infants, and children are able to ...
Levy S M - - 1997
The early use of fluoride dentifrice and use of larger quantities recently have been identified as risk factors for dental fluorosis. However, little is known about fluoride dentifrice use and ingestion among infants and young children whose developing permanent teeth are at risk for dental fluorosis. This paper reports on ...
Sugiura H - - 1997
To investigate the prevalence of infantile and early childhood eczema in a Japanese population, we clinically inspected the entire bodies of 4-month-old infants (341 cases), 10-month-old infants (339 cases) and 3-year-old children (341 cases). The examination was performed in spring, when exacerbations of infantile and childhood eczema most frequently occur ...
DeMuri G P - - 1996
Afebrile or atypical pneumonia is a relatively common illness in infants. These children often present afebrile with diffuse or bilateral infiltrates on chest radiograph. The definition and causes of this clinical entity are discussed. The role of agents such as Chlamydia, Ureaplasma, Pneumocystis, and viruses is elucidated. Techniques for diagnosis ...
Holmdahl G - - 1996
PURPOSE: We present the 4-hour voiding observation as a method for basic assessment of bladder function in infants and nontoilet trained children. MATERIALS AND METHODS: Voiding pattern, including number of voidings, voided volume, bladder capacity and residual urine for 4 hours, was determined noninvasively in 43 healthy infants. RESULTS: The ...
Friedman F D - - 1996
In recent years, the intraosseous technique has dramatically improved the speed at which vascular access may be achieved in critically ill children, and adenosine has been shown to rapidly convert supraventricular tachycardia to normal sinus rhythm. Until now, no report has demonstrated that this drug may be effectively given by ...
Mason J D - - 1996
The infant or child that presents with abdominal pain must be evaluated with a careful history, physical examination, and selective laboratory studies. There are a few diagnoses that the emergency physician should always consider as "life threatening." In the event of any uncertainty in the diagnosis of conditions like appendicitis, ...
Schwartz R A - - 1996
Erythema toxicum neonatorum is a common finding of unknown etiology affecting healthy newborn children, particularly those born at term. It is seen in the first days of life, but rarely at birth. Infants with it often have sterile papulopustules containing a predominance of eosinophils. It is important to distinguish from ...
Turner B J - - 1996
OBJECTIVES: To compare the use of medical services by pediatric and adult patients with acquired immunodeficiency syndrome (AIDS) in the 6 months before and after the diagnosis of AIDS when demand for care is often high and to study the influence of human immunodeficiency virus specialty care on survival of ...
Zeharia A - - 1996
Thirty-four infants and children were prescribed bifonazole 1% shampoo as a treatment for lesions of scalp seborrheic dermatitis. All but one were cured or showed improvement within a short period. No serious side effects were observed. We conclude that bifonazole 1% shampoo is an effective and safe treatment for lesions ...
Wong F H - - 1996
Breath hydrogen (H2) analysis was used to study lactose malabsorption in Southern Chinese children and infants. End-expired air was collected in 85 children using a modified anaesthesia bag system; while in infants, a novel automated end-expired sampling device was constructed and tested on 45 term and 27 preterm infants. Hydrogen ...
Gottschau A - - 1995
A statistical model for interval censored data is described. Assuming a piecewise constant incidence enables us to analyse very unbalanced data in a generalized linear model. The distribution of age at first appearance of P. falciparum parasites in infants in Liberia has been estimated. A new graphical method for presentation ...
Dingle A F - - 1995
Fifty children with otitis media with effusion undergoing grommet insertion had into one ear a Mini-titanium grommet inserted and into the other ear a Mini-teflon grommet. Post-operative follow-up until after extrusion of the grommets demonstrated only a small difference between the extrusion times of the two grommets (a significant difference ...
Haight M - - 1995
Development of smaller instruments and emergence of pediatric gastroenterology as a legitimate and growing subspecialty have been primary factors involved in effective utilization of gastrointestinal endoscopy in the care of infants and children. Endoscopic gastrointestinal procedures are now common in most major pediatric centers, and they can be safely performed ...
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