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Uijterschout L L Department of Pediatrics, Juliana Children's Hospital/HAGA Teaching Hospital, The Hague, The - - 2014
Background/objectives:Preterm infants are at risk of iron deficiency (ID). In the Netherlands, preterm infants born after 32 weeks of gestational age (GA) do not receive iron supplementation on a routine basis. We hypothesized that dietary iron intake in these infants might not be sufficient to meet the high iron requirements ...
Powell Russell A RA Department of Psychology, Grant MacEwan - - 2014
In 1920, John B. Watson and Rosalie Rayner attempted to condition a phobia in a young infant named "Albert B." In 2009, Beck, Levinson, and Irons proposed that Little Albert, as he is now known, was actually an infant named Douglas Merritte. More recently, Fridlund, Beck, Goldie, and Irons (2012) ...
Yapakçı Ece E Division of Neonatology, Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, - - 2014
Inferior vena cava (IVC) oxygen saturation as an indicator of mixed venous oxygenation may be valuable for understanding postnatal adaptations in newborn infants. It is unknown how this parameter progresses in critically ill premature infants. To investigate IVC oxygen saturation during the first three days of life in preterm infants ...
Shaireen Huma - - 2014
Little evidence exists regarding the optimal concentration of oxygen to use in the treatment of term neonates with spontaneous pneumothorax (SP). The practice of using high oxygen concentrations to promote "nitrogen washout" still exists at many centers. The aim of this study was to identify the time to clinical resolution ...
Schushan-Eisen Irit I Department of Neonatology, The Edmond and Lili Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 52621, Ramat Gan, - - 2014
Decreased bone density has been found among infants of diabetic mothers and among large-for-gestational-age newborns. To evaluate which etiologies (physical or metabolic effect) have the greatest impact on neonatal bone density. A case-control study was conducted that included two study groups: one comprising 20 appropriate-for-gestational-age (AGA) infants of gestational diabetic ...
Said Mohamed Ben MB Department of Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, F-69004 Lyon, France; Faculty of Medicine of Tunis, University of Tunis El-Manar, 1007 Bab Saâdoun, Tunis, - - 2014
Gross blood in stools is a peculiar entity in preterm infants, but little is known about its etiology. As gut microbiota can be distorted in preterm infants, we aimed to evaluate the gut microbiota in infants with gross blood in stools. In a prospective, controlled, single-center study, we enrolled all ...
Poppitt Sally D SD *Human Nutrition Unit, School of Biological Sciences, University of Auckland, New Zealand †Panchsheel Hospital, Yamuna Vihar ‡Sarvodaya Child Care, Pitampura, New Delhi §M.V. Hospital & Research Centre, Lucknow, India ||Research and Development Centre, Palmerston North ¶University of Otago, Dunedin, New - - 2014
Rotavirus (RV) is a leading cause of morbidity and mortality in children younger than 5 years of age, presenting commonly with diarrhoeal symptoms. In a prospective 12-week double-blind randomised controlled trial we assessed acceptability and efficacy of a high-ganglioside complex milk lipid (CML) for prevention of RV infection in 450 ...
Ortega-Insaurralde Isabel I Centro de Investigaciones de Plagas e Insecticidas (CONICET-CITEDEF), Juan Bautista de La Salle 4397, B1603ALO, Villa Martelli, Buenos Aires, Argentina, - - 2014
Head lice lay eggs in human head hairs in order to reproduce. There is a difficulty associated to the process of detaching these eggs: they are tightly gripped to the hair by a secretion produced by female head lice. The physical removal of eggs has become an important part of ...
Nachanakian Antoine A Neurosurgery Department, Saint Georges Hospital and University Medical Center, Balamand University, Beirut, - - 2014
We report on the youngest infant treated with modified functional hemispherectomy at the age of 5 months for Ohtahara syndrome and hemimegalencephaly as underlying pathology, and we depict the favorable outcome regarding seizure control and psychomotor development. These results highlight the potential usefulness of early surgery in such conditions.
Skuladottir Hildur H Department of Plastic Surgery, Haukeland University Hospital, Bergen, Norway; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. Electronic address: - - 2014
Exposure of pregnant mice to corticosteroids can produce oral clefts in offspring. Although data in humans are more mixed, recent reports have suggested that dermatologic steroids are associated with oral clefts. We investigated maternal first-trimester exposure to corticosteroids (focusing on dermatologic uses) and oral clefts in offspring using two population-based ...
Raper Jessica J Department of Psychology, Emory University, 36 Eagle Row, Atlanta, GA, 30322; Yerkes National Primate Research Center, 954 Gatewood Rd NE, Atlanta, GA, - - 2014
The current study examined the effects of neonatal amygdala lesions on mother-infant interactions in rhesus monkeys reared in large species-typical social groups. Focal observations of mother-infant interactions were collected in their social group for the first 12 months postpartum on infants that had received amygdala lesions (Neo-A) at 24-25 days ...
Aydemir Ozge O Department of Neonatology, Etlik Zübeyde Hanım Women's Health Teaching and Research Hospital, Ankara, - - 2014
Abstract Objective: Nitric oxide (NO) formed by the enzyme NO synthase (NOS) from L-arginine, is an important mediator for pathogen elimination. Being a potent vasodilator NO is implicated in hypotension and decreased organ perfusion in sepsis. Asymmetric dimethylarginine (ADMA) is an endogenous NOS inhibitor. We investigated ADMA and L-arginine levels ...
Neary Marianne T MT MRC National Institute for Medical Research, Mill Hill, London NW7 - - 2014
Fetal cardiomyocyte adaptation to low levels of oxygen in utero is incompletely understood, and is of interest as hypoxia tolerance is lost after birth, leading to vulnerability of adult cardiomyocytes. It is known that cardiac mitochondrial morphology, number and function change significantly following birth, although the underlying molecular mechanisms and ...
Karl Jenni M JM Department of Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive West, Lethbridge, AB, T1K 3M4, Canada, - - 2014
The Dual Visuomotor Channel theory posits that reaching consists of two movements mediated by separate but interacting visuomotor pathways that project from occipital to parietofrontal cortex. The Reach transports and orients the hand to the target while the Grasp opens and closes the hand for target purchase. Adults rely on ...
Studer Jacqueline J Institute of Legal Medicine, University of Zurich, Winterthurerstrasse 190/52, 8057, Zurich, - - 2014
Catecholamines, especially noradrenalin, are essential in the control of respiration and arousal. Thus, an impaired production of these neurotransmitters may contribute to the occurrence of sudden infant death syndrome (SIDS). The first step of the noradrenergic synthesis pathway is catalyzed by the enzyme tyrosine hydroxylase (TH). The TH-encoding gene contains ...
Timby Niklas N Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, - - 2014
A high level of parental control of feeding and disturbed energy self-regulation has previously been suggested as a mechanism for the accelerated growth observed in formula-fed compared to breast-fed infants. This study explored factors associated with parental control of feeding in a population of formula-fed infants with high levels of ...
Varner Michael W MW Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, - - 2014
Objective To test whether elevated umbilical cord serum inflammatory cytokine levels predicted subsequent cerebral palsy (CP) or neurodevelopmental delay (NDD). Study Design Nested case-control analysis within a clinical trial of antenatal magnesium sulfate (MgSO4) before anticipated preterm birth (PTB) for prevention of CP, with evaluation of surviving children at the age of ...
Malwade Ujjwala S US Department of Paediatrics, Mater Children's Hospital, Raymond Terrace, South Brisbane, Queensland, Australia, - - 2014
Phototherapy is commonly used for the treatment of neonatal jaundice, and home-based phototherapy is now being used in certain centres. Home-based phototherapy offers possible advantages by avoiding prolonged hospital admissions, promoting mother-infant bonding and reducing hospitalisation costs. Potential problems include increased duration of phototherapy, increased readmission to hospital and increased ...
Dawson April L AL National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, - - 2014
Methotrexate is an anti-folate medication that is associated with increased risk of multiple birth defects. Using data from the National Birth Defects Prevention Study, a case-control study of major birth defects in the United States, we examined mothers exposed to methotrexate. The study population included mothers of live-born infants without ...
Kim Mimi S MS Division of Endocrinology (M.S.K., A.R.-L., B.B., A.H.P., S.H., M.E.G.), Children's Hospital Los Angeles, The Saban Research Institute (M.S.K., M.E.G.), and the University of Southern California (M.S.K., C.J.L., M.E.G.), Los Angeles, California - - 2014
Context: Classical congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency can cause life-threatening adrenal crises as well as severe hypoglycemia, especially in very young children. Studies of CAH patients 4 years old or older have found abnormal morphology and function of the adrenal medulla and lower levels of epinephrine and ...
Wilinska Maria - - 2014
Managing the oxygen saturation of preterm infants to a target range has been the standard of care for a decade. Changes in target ranges have been shown to significantly impact mortality and morbidity. Selecting and implementing the optimal target range are complicated not only by issues of training, but also ...
Bulut Gulcin G Department of Paediatric - - 2014
Abstract Objective. The aim of this study is to verify the existence of an association between maternal periodontal disease and pre-term delivery in an unselected population of post-partum Turkish women. Materials and methods. This case-control study was conducted on 100 women who gave birth in either a special or a ...
Yao Manjiang M *Research and Development, Nestlé Nutrition, King of Prussia, PA, USA †Department of Food Science and Human Nutrition, University of Illinois, Urbana, IL, USA ‡Pediatrics, Asian Hospital and Medical Center, Muntinlupa City, Philippines §Research and Development, Wyeth Nutritionals Ireland, Askeaton, Ireland ||Medical, Wyeth Philippines, Inc., Makati City, Philippines ¶Pfizer Inc., Bridgewater, NJ, USA #Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, - - 2014
Levels of stool fatty acid soaps and beneficial bacteria differ between formula-fed and breast-fed infants; addition of specific formula ingredients may reduce these differences. This study evaluated the effects of a term infant formula containing high sn-2 palmitate (sn-2) or an identical formula supplemented with oligofructose (OF) at two concentrations ...
Malkar Manish B MB 1] Section of Neonatology, The Neonatal and Infant Feeding Disorders Program, Nationwide Children's Hospital, Columbus, Ohio, USA [2] Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, - - 2014
Background:Aero-digestive morbidities are common in congenital heart disease infants and mechanisms are unclear. We hypothesized that adaptive pharyngo-esophageal motility reflexes are different in surgical congenital heart disease infants (S-CHD) vs. nonsurgical congenital heart disease infants (CHD) and healthy controls.Methods:Abrupt pharyngeal provocation was performed with graded water infusions using purpose-built micro-manometry. ...
Ince Deniz Anuk DA Department of Paediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Ankara, - - 2014
Despite extensive research, there is still controversy regarding the time at which sucking and swallowing functions mature in preterm infants. This study aimed to evaluate maturation using the non-invasive method of swallowing sound. We compared 52 preterm infants of between 27 and 36 weeks' gestational age with a control group ...
Tsai Ming-Horng MH Division of Neonatology and Pediatric Hematology/Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, Yunlin, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Chang Gung University of Science and Technology, Chiayi, - - 2014
We aimed to characterize the incidence, clinical features, risk factors and outcomes of recurrent late-onset sepsis (LOS) in the neonatal intensive care unit (NICU). All neonates with LOS from the NICU of a tertiary-level teaching hospital in Northern Taiwan between 2004 and 2011 were enrolled for analyses. A case-control study ...
Hua Meiling M Thomas Jefferson University, Philadelphia, - - 2014
We sought to determine whether the diagnosis of maternal chorioamnionitis is a risk factor for the subsequent development of neonatal necrotizing enterocolitis (NEC). We performed a retrospective case-control study of all neonates diagnosed with NEC at our institution between 2009 and 2012. Patients with NEC were identified from an existing ...
Merras-Salmio Laura - - 2014
To determine whether specific infant behavioural characteristics are present in children suspected of cow's milk allergy because of gastrointestinal symptoms. We prospectively recruited 57 children (median age 8.7 months) with a suspicion of gastrointestinally manifested cow's milk protein allergy (GI-CMPA). None had detectable cow's milk-specific IgE. Mothers were asked to ...
Chen Qingquan Q Department of Laboratory Medicine, Medical Technology and Engineering College, Fujian Medical University, 350004, Fuzhou, People's Republic of - - 2014
Neonatal sepsis remains an important and common cause of morbidity and mortality among newborn infants, especially in developing countries. The aim of the present study was to determine whether serum trypsin levels and genotypes of cationic trypsinogen (PRSS1) gene could be served as markers for predicting neonatal sepsis. The serum ...
Poppitt Sally D SD *Human Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland †Fonterra Research and Development Centre, Palmerston North ‡University of Otago, Dunedin, New Zealand §Panchsheel Hospital, Yamuna Vihar, New Delhi ||Sarvodaya Child Care, Pitampura, New Delhi ¶M.V. Hospital & Research Centre, Lucknow, - - 2014
Rotavirus (RV) is a leading cause of morbidity and mortality in children under 5-yrs, presenting commonly with diarrhoeal symptoms. In a prospective 12-wk double-blind randomised controlled trial we assessed acceptability and efficacy of a high-ganglioside complex milk lipid (CML) for prevention of RV infection in 450 infants, aged 8-24 months, ...
Berseth C L CL Department of Medical Affairs, Clinical Research, Mead Johnson Nutrition, 2400 West Lloyd Expy, Evansville, IN 47721, - - 2014
We report the fatty acid composition of mother׳s own human milk from one of the largest US cohorts of lactating mothers of preterm infants. Milk fatty acid data were used as a proxy for intake at enrollment in infants (n=150) who received human milk with a powder human milk fortifier ...
Marsh Courtney A CA Department of Obstetrics and Gynecology, University of Kansas, Kansas City, Kansas; At the time this project was conducted, Dr. Marsh was a CDC Experience Fellow at the Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: - - 2014
To assess maternal prenatal use of analgesics and risk of cardiovascular malformations (CVM) in the offspring. Data from the Baltimore-Washington Infant Study, a population based case-control investigation of CVM, were used to examine selected isolated CVM diagnoses and maternal analgesic use during the periconceptional period (3 months before and after ...
Huusko Johanna M JM Department of Pediatrics, Institute of Clinical Medicine, and Medical Research Center Oulu, University of Oulu, Oulu, Finland; Department of Children and Adolescents, Oulu University Hospital, Oulu, - - 2014
Bronchopulmonary dysplasia (BPD) is a chronic inflammatory lung disease that affects infants born preterm. Family studies indicate that BPD has a significant genetic component. Rationale: We assessed the gene encoding Kit ligand (KITLG) as a candidate for genetic predisposition to moderate-to-severe BPD (controls were infants with no or mild BPD). ...
Müller-Starck Jens J From the Department of Neuroanatomy, Ludwig Maximilians-University of Munich, Munich, Germany (JMS, MCK, NA, NC, EH, TH, KS, HGF, SM, CS); and Institute of Forensic Medicine, University of Rostock, Rostock, Germany (AB) and Fishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York - - 2014
Sudden infant death syndrome (SIDS) is the leading cause of mortality in infants younger than 1 year in developed countries, but its primary cause remains unknown. Some studies suggest that there may be hypoxia in the cerebellum in SIDS subjects, but mean total Purkinje cell numbers in SIDS versus controls ...
Studer Jacqueline J Institute of Legal Medicine, University of Zurich, Winterthurerstrasse 190/52, 8057, Zurich, Switzerland, - - 2014
The sodium/proton exchanger protein 3 (NHE3) is located in chemosensitive areas of the medulla oblongata and plays an important role in the central control of respiration. Overexpression of NHE3 is correlated with lower respiration and might therefore contribute to the vulnerability of infants dying suddenly and unexpected (sudden infant death ...
Porter Samuel G SG Mayo Medical School, College of Medicine, Rochester, MN. Electronic address: - - 2014
To compare blood thiamine concentrations, echocardiography findings, and plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in infants with clinically diagnosed beriberi and healthy matched controls, and to evaluate changes after thiamine treatment. Sixty-two Cambodian infants (20 cases and 42 controls), aged 2-47 weeks, were enrolled in this prospective study. Echocardiography ...
Kaufman David A DA Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: - - 2014
Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. We conducted a case-control analysis of efficacy and safety of fluconazole prophylaxis from a multicenter ...
Padilla Nelly N Department of Women's and Children's - - 2014
Premature exposure to the extrauterine environment negatively affects the brains' developmental trajectory. Our aim was to determine whether extremely preterm (EPT) infants, with no evidence of focal brain lesions, show morphological brain differences when compared with term-born infants. Additionally, we investigated associations between perinatal factors and neuroanatomical alterations. Conventional magnetic ...
Dusing Stacey C SC Motor Development Lab, Department of Physical Therapy, Virginia Commonwealth University, Richmond, VA, United States. Electronic address: - - 2014
Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and reaching in infants ...
Hallenberger Antonietta A Department of Neonatology, University Children's Hospital, Tuebingen, - - 2014
In preterm infants receiving supplemental oxygen, routine manual control (RMC) of the fraction of inspired oxygen (FIO2) is often difficult and time consuming. We developed a system for closed-loop automatic control (CLAC) of the FIO2 and demonstrated its short-term safety and efficacy in a single-center study. The objective of this ...
Kharoshankaya Liudmila L Department of Paediatrics and Child Health, University College Cork, Cork, Ireland; Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), Cork University Maternity Hospital, Cork, - - 2014
We present an unusual case of persistent generalized electroencephalography (EEG) suppression and right-sided clonic seizures in a male infant born at 40(+2) weeks' gestation, birthweight 3240g, with an isolated unilateral thalamic stroke. The EEG at 13 hours after birth showed a generalized very low amplitude background pattern, which progressed to frequent ...
Barbosa Maricele Nascimento MN Departamento de Fisiologia, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Campus Universitário, Caixa Postal 1511, Natal, RN, 59078-970, Brazil, - - 2014
Parental care in mammals is influenced by sensory stimuli from infants, such as sight and sound, and by changes in the hormone levels of caretakers. To determine the responsiveness of common marmoset (Callithrix jacchus) adult males with and without previous experience in caretaking to newborn sensory cues, we exposed twelve ...
Kawaza Kondwani K Department of Pediatrics, College of Medicine, Queen Elizabeth Central Hospital, Blantyre, - - 2014
Respiratory failure is a leading cause of neonatal mortality in the developing world. Bubble continuous positive airway pressure (bCPAP) is a safe, effective intervention for infants with respiratory distress and is widely used in developed countries. Because of its high cost, bCPAP is not widely utilized in low-resource settings. We ...
León Inmaculada I Faculty of Psychology, University of La Laguna, La Laguna, Canary Islands, - - 2014
Results illustrating an atypical neural processing in the early and late differentiation of infant faces have been obtained with neglectful mothers. The present study explores whether a different pattern of response is observed when using non-infant affective pictures. We examined the event-related evoked potentials and induced delta, theta and alpha ...
Prendergast Andrew J AJ Centre for Paediatrics, Blizard Institute, Queen Mary University of London, London, United Kingdom ; Zvitambo Institute for Maternal Child Health Research, Harare, Zimbabwe ; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of - - 2014
Stunting affects one-third of children in developing countries, but the causes remain unclear. We hypothesized that enteropathy leads to low-grade inflammation, which suppresses the growth hormone-IGF axis and mediates stunting. We conducted a case-control study of 202 HIV-unexposed Zimbabwean infants who were stunted (height-for-age Z-score (HAZ) <-2; cases) or non-stunted ...
Petrus Ncm N Department of Paediatric Respiratory Medicine and Allergy, Emma Children's Hospital AMC, Amsterdam, The Netherlands. - - 2014
The double blind placebo controlled food challenge (DBPCFC) is the gold standard for diagnosing cow's milk allergy (CMA). However, false-negative DBPCFC have been reported. We present 2 cases with a false negative DBPCFC in exclusively breastfed infants suspected of CMA. These cases highlight the occurrence of severe allergic reactions of ...
Tann Cally J CJ Clinical Research Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom; Mulago University Hospital, Kampala, - - 2014
In neonatal encephalopathy (NE), infectious co-morbidity is difficult to diagnose accurately, but may increase the vulnerability of the developing brain to hypoxia-ischemia. We developed a novel panel of species-specific real-time PCR assays to identify bloodstream pathogens amongst newborns with and without NE in Uganda. Multiplex real-time PCR assays for important ...
Alijahan Rahele R Province Heath Center, Ardabil University of Medical Science, Ardabil, - - 2014
Preterm birth is a leading cause of perinatal mortality and long-term morbidity as well as the long-term health consequences and cognitive outcomes. Present study was conducted to determine prevalence and risk factors associated with preterm birth in Ardabil, Iran. A case control study was conducted between Nov 2010 and July ...
Barlow S M - - 2013
Objective:Controlled somatosensory stimulation strategies have demonstrated merit in developing oral feeding skills in premature infants who lack a functional suck, however, the effects of orosensory entrainment stimulation on electrocortical dynamics is unknown. The objective of the study was to determine the effects of servo-controlled pneumatic orocutaneous stimulation presented during gavage ...
Martin Richard M RM School of Social and Community Medicine, University of Bristol, Bristol, UK (R.M.M., R.P., Y.F., G.D.S.); Medical Research Council/University of Bristol Integrated Epidemiology Unit, University of Bristol, Bristol, UK (R.M.M., G.D.S.); National Institute for Health Research, Bristol Biomedical Research Unit in Nutrition, Bristol, UK (R.M.M.); Departments of Pediatrics and of Epidemiology, Biostatistics, and Occupational Health, McGill University Faculty of Medicine, Montreal, Canada (M.S.K.); National Research and Applied Medicine Mother and Child Centre, Minsk, Belarus (K.V., N.B., N.S., N.G.); Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK (T.P.); and Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA (J.T., M.W.G., - - 2014
The duration and exclusivity of breastfeeding in infancy have been inversely associated with future cardiometabolic risk. We investigated the effects of an experimental intervention to promote increased duration of exclusive breastfeeding on cardiometabolic risk factors in childhood. We followed-up children in the Promotion of Breastfeeding Intervention Trial, a cluster-randomized trial ...
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