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Poppitt Sally D SD *Human Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland †Fonterra Research and Development Centre, Palmerston North ‡University of Otago, Dunedin, New Zealand §Panchsheel Hospital, Yamuna Vihar, New Delhi ||Sarvodaya Child Care, Pitampura, New Delhi ¶M.V. Hospital & Research Centre, Lucknow, - - 2014
Rotavirus (RV) is a leading cause of morbidity and mortality in children under 5-yrs, presenting commonly with diarrhoeal symptoms. In a prospective 12-wk double-blind randomised controlled trial we assessed acceptability and efficacy of a high-ganglioside complex milk lipid (CML) for prevention of RV infection in 450 infants, aged 8-24 months, ...
Marsh Courtney A CA Department of Obstetrics and Gynecology, University of Kansas, Kansas City, Kansas; At the time this project was conducted, Dr. Marsh was a CDC Experience Fellow at the Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: - - 2014
To assess maternal prenatal use of analgesics and risk of cardiovascular malformations (CVM) in the offspring. Data from the Baltimore-Washington Infant Study, a population based case-control investigation of CVM, were used to examine selected isolated CVM diagnoses and maternal analgesic use during the periconceptional period (3 months before and after ...
Huusko Johanna M JM Department of Pediatrics, Institute of Clinical Medicine, and Medical Research Center Oulu, University of Oulu, Oulu, Finland; Department of Children and Adolescents, Oulu University Hospital, Oulu, - - 2014
Bronchopulmonary dysplasia (BPD) is a chronic inflammatory lung disease that affects infants born preterm. Family studies indicate that BPD has a significant genetic component. Rationale: We assessed the gene encoding Kit ligand (KITLG) as a candidate for genetic predisposition to moderate-to-severe BPD (controls were infants with no or mild BPD). ...
Müller-Starck Jens J From the Department of Neuroanatomy, Ludwig Maximilians-University of Munich, Munich, Germany (JMS, MCK, NA, NC, EH, TH, KS, HGF, SM, CS); and Institute of Forensic Medicine, University of Rostock, Rostock, Germany (AB) and Fishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York - - 2014
Sudden infant death syndrome (SIDS) is the leading cause of mortality in infants younger than 1 year in developed countries, but its primary cause remains unknown. Some studies suggest that there may be hypoxia in the cerebellum in SIDS subjects, but mean total Purkinje cell numbers in SIDS versus controls ...
Studer Jacqueline J Institute of Legal Medicine, University of Zurich, Winterthurerstrasse 190/52, 8057, Zurich, Switzerland, - - 2014
The sodium/proton exchanger protein 3 (NHE3) is located in chemosensitive areas of the medulla oblongata and plays an important role in the central control of respiration. Overexpression of NHE3 is correlated with lower respiration and might therefore contribute to the vulnerability of infants dying suddenly and unexpected (sudden infant death ...
Porter Samuel G SG Mayo Medical School, College of Medicine, Rochester, MN. Electronic address: - - 2014
To compare blood thiamine concentrations, echocardiography findings, and plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in infants with clinically diagnosed beriberi and healthy matched controls, and to evaluate changes after thiamine treatment. Sixty-two Cambodian infants (20 cases and 42 controls), aged 2-47 weeks, were enrolled in this prospective study. Echocardiography ...
Kaufman David A DA Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: - - 2014
Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. We conducted a case-control analysis of efficacy and safety of fluconazole prophylaxis from a multicenter ...
Padilla Nelly N Department of Women's and Children's - - 2014
Premature exposure to the extrauterine environment negatively affects the brains' developmental trajectory. Our aim was to determine whether extremely preterm (EPT) infants, with no evidence of focal brain lesions, show morphological brain differences when compared with term-born infants. Additionally, we investigated associations between perinatal factors and neuroanatomical alterations. Conventional magnetic ...
Dusing Stacey C SC Motor Development Lab, Department of Physical Therapy, Virginia Commonwealth University, Richmond, VA, United States. Electronic address: - - 2014
Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and reaching in infants ...
Hallenberger Antonietta A Department of Neonatology, University Children's Hospital, Tuebingen, - - 2014
In preterm infants receiving supplemental oxygen, routine manual control (RMC) of the fraction of inspired oxygen (FIO2) is often difficult and time consuming. We developed a system for closed-loop automatic control (CLAC) of the FIO2 and demonstrated its short-term safety and efficacy in a single-center study. The objective of this ...
Kharoshankaya Liudmila L Department of Paediatrics and Child Health, University College Cork, Cork, Ireland; Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), Cork University Maternity Hospital, Cork, - - 2014
We present an unusual case of persistent generalized electroencephalography (EEG) suppression and right-sided clonic seizures in a male infant born at 40(+2) weeks' gestation, birthweight 3240g, with an isolated unilateral thalamic stroke. The EEG at 13 hours after birth showed a generalized very low amplitude background pattern, which progressed to frequent ...
Barbosa Maricele Nascimento MN Departamento de Fisiologia, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Campus Universitário, Caixa Postal 1511, Natal, RN, 59078-970, Brazil, - - 2014
Parental care in mammals is influenced by sensory stimuli from infants, such as sight and sound, and by changes in the hormone levels of caretakers. To determine the responsiveness of common marmoset (Callithrix jacchus) adult males with and without previous experience in caretaking to newborn sensory cues, we exposed twelve ...
Kawaza Kondwani K Department of Pediatrics, College of Medicine, Queen Elizabeth Central Hospital, Blantyre, - - 2014
Respiratory failure is a leading cause of neonatal mortality in the developing world. Bubble continuous positive airway pressure (bCPAP) is a safe, effective intervention for infants with respiratory distress and is widely used in developed countries. Because of its high cost, bCPAP is not widely utilized in low-resource settings. We ...
León Inmaculada I Faculty of Psychology, University of La Laguna, La Laguna, Canary Islands, - - 2014
Results illustrating an atypical neural processing in the early and late differentiation of infant faces have been obtained with neglectful mothers. The present study explores whether a different pattern of response is observed when using non-infant affective pictures. We examined the event-related evoked potentials and induced delta, theta and alpha ...
Prendergast Andrew J AJ Centre for Paediatrics, Blizard Institute, Queen Mary University of London, London, United Kingdom ; Zvitambo Institute for Maternal Child Health Research, Harare, Zimbabwe ; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of - - 2014
Stunting affects one-third of children in developing countries, but the causes remain unclear. We hypothesized that enteropathy leads to low-grade inflammation, which suppresses the growth hormone-IGF axis and mediates stunting. We conducted a case-control study of 202 HIV-unexposed Zimbabwean infants who were stunted (height-for-age Z-score (HAZ) <-2; cases) or non-stunted ...
Petrus Ncm N Department of Paediatric Respiratory Medicine and Allergy, Emma Children's Hospital AMC, Amsterdam, The Netherlands. - - 2014
The double blind placebo controlled food challenge (DBPCFC) is the gold standard for diagnosing cow's milk allergy (CMA). However, false-negative DBPCFC have been reported. We present 2 cases with a false negative DBPCFC in exclusively breastfed infants suspected of CMA. These cases highlight the occurrence of severe allergic reactions of ...
Barlow S M - - 2013
Objective:Controlled somatosensory stimulation strategies have demonstrated merit in developing oral feeding skills in premature infants who lack a functional suck, however, the effects of orosensory entrainment stimulation on electrocortical dynamics is unknown. The objective of the study was to determine the effects of servo-controlled pneumatic orocutaneous stimulation presented during gavage ...
Martin Richard M RM School of Social and Community Medicine, University of Bristol, Bristol, UK (R.M.M., R.P., Y.F., G.D.S.); Medical Research Council/University of Bristol Integrated Epidemiology Unit, University of Bristol, Bristol, UK (R.M.M., G.D.S.); National Institute for Health Research, Bristol Biomedical Research Unit in Nutrition, Bristol, UK (R.M.M.); Departments of Pediatrics and of Epidemiology, Biostatistics, and Occupational Health, McGill University Faculty of Medicine, Montreal, Canada (M.S.K.); National Research and Applied Medicine Mother and Child Centre, Minsk, Belarus (K.V., N.B., N.S., N.G.); Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK (T.P.); and Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA (J.T., M.W.G., - - 2014
The duration and exclusivity of breastfeeding in infancy have been inversely associated with future cardiometabolic risk. We investigated the effects of an experimental intervention to promote increased duration of exclusive breastfeeding on cardiometabolic risk factors in childhood. We followed-up children in the Promotion of Breastfeeding Intervention Trial, a cluster-randomized trial ...
Sankararaman Senthilkumar - - 2013
Studies documented that platelet activating factor (PAF) and the enzyme platelet activating factor acetylhydrolase (PAFAH) play a very important role in the pathogenesis of neonatal necrotizing enterocolitis (NEC). In this retrospective, case-controlled pilot study, the authors investigated the prevalence of single nucleotide polymorphisms (Ile198Thr and Ala379Val) of the PAFAH gene. ...
Boskabadi Hassan H Department of Pediatrics, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2013
Objective(s): Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific. We have evaluated serum IL-6, 8 and 10 as potential early diagnostic markers of neonatal infection and their relationship to mortality rate and poor prognosis. Materials and Methods ...
Summer Suzanne S - - 2013
Sleeping Metabolic Rate (SMR) is used as a proxy for Basal Metabolic Rate in infants, when measurement while awake is not practical. Measuring SMR via indirect calorimetry (IC) can be useful for assessing feeding adequacy especially in compromised neonates. Standard IC equipment, including the hood placed over the head, is ...
Graves S W - - 2013
Endogenous digoxin-like factor (EDLF) has been linked to vasoconstriction, altered membrane transport and apoptosis. Our objective was to determine whether increased EDLF in the cord sera of preterm infants was associated with an increased incidence of necrotizing enterocolitis (NEC). Cord sera from pregnant women enrolled in a randomized trial of ...
Matatyaho-Bullaro Dalit J - - 2013
This study assessed whether specific types of object motion, which predominate in maternal naming to preverbal infants, facilitate word mapping by infants. A total of 60 full-term 8-month-old infants were habituated to two spoken words, /bæf/ and /wem/, synchronous with the handheld motions of a toy dragonfly and a fish ...
Platts-Mills James A JA Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia; Haydom Lutheran Hospital, Haydom, Tanzania; Kilimanjaro Clinical Research Institute, Moshi, Tanzania; Fogarty International Center, National Institutes of Health, Bethesda, - - 2014
Etiologic studies of diarrhea are limited by uneven diagnostic methods and frequent asymptomatic detection of enteropathogens. Polymerase chain reaction-based stool pathogen quantification may help distinguish clinically significant infections. We performed a nested case-control study of diarrhea in infants from a community-based birth cohort in Tanzania. We tested 71 diarrheal samples ...
Hadders-Algra Mijna - - 2013
Successful reaching requires postural control, either by active regulation or by postural support. The present paper reviews literature on typical and atypical development of reaching and postural control during infancy. Typically, reaching movements end in grasping around 4 months of age. Initially, reaches are characterized by large variation, including many trajectory ...
Verspyck Eric - - 2013
To determine if preterm premature rupture of membranes (PPROM) before 24 weeks is an independent risk factor for poor outcome in preterm neonates. A retrospective comparative cohort study was conducted, including viable premature infants born between 25 and 34 weeks gestation. Each preterm case with early PPROM was matched with ...
Kumar Manoj - - 2013
Epidural analgesia is the commonest mode for providing pain relief in labour, with a combination of bupivacaine and fentanyl most often used in practice. To test whether late-preterm and term neonates exposed to opioids in epidural analgesia in labour are more likely to develop respiratory distress in the immediate neonatal ...
Hsu Jen-Fu - - 2013
We aimed to characterize the clinical manifestations and outcomes of patients with Acinetobacter baumannii bacteremia in the neonatal intensive care unit (NICU). All patients with A baumannii bacteremia in our NICU from 2004 to 2010 were reviewed. A matched case-control study was performed by comparing each case of A baumannii ...
Song Dongli - - 2013
Background:Stimulation of the nervous system plays a central role in brain development and neurodevelopmental outcome. Thalamocortical and corticocortical development is diminished in premature infants and correlated to electroencephalography (EEG) progression. The purpose of this study was to determine the effects of orocutaneous stimulation on the modulation of spectral edge frequency, ...
Aikio Outi - - 2013
Abstract Objectives. Persistent ductus arteriosus (PDA) delays the recovery of very preterm infants (VLGA, gestation <32 weeks). Indomethacin/ibuprofen treatment and ligation of PDA have complications. As a prostaglandin synthase inhibitor paracetamol may also promote the closure of ductus arteriosus. We studied retrospectively whether early paracetamol therapy was associated with decreased ...
Feldman Ruth - - 2013
Maternal-newborn contact enhances organization of the infant's physiological systems, including stress reactivity, autonomic functioning, and sleep patterns, and supports maturation of the prefrontal cortex and its ensuing effects on cognitive and behavioral control. Premature birth disrupts brain development and is associated with maternal separation and disturbances of contact-sensitive systems. However, ...
Fiscus Susan A - - 2013
The qualitative Roche HIV-1 DNA Amplicor assay has been used for the past 20 years to diagnose HIV infection in infants and young children, but is being phased out; hence, alternative assays must be found. The Gen-Probe Aptima qualitative HIV-1 RNA assay is currently the only FDA cleared HIV-1 nucleic ...
Li Qian Q Department of Epidemiology, Harvard School of Public Health, Boston, - - 2013
Several studies have reported an association between use of specific antihistamines in early pregnancy and certain specific birth defects. To test 16 previously hypothesized associations between specific antihistamines and specific birth defects, and to identify possible new associations. We used 1998-2010 data from the Slone Epidemiology Center Birth Defects Study, ...
Martinez-Biarge Miriam - - 2013
To determine whether antepartum factors alone, intrapartum factors alone, or both in combination, are associated with term neonatal hypoxic-ischemic encephalopathy (HIE).METHODS:A total of 405 infants ≥35 weeks' gestation with early encephalopathy, born between 1992 and 2007, were compared with 239 neurologically normal infants born between 1996 and 1997. All cases ...
Allen T - - 2013
Sudden Infant Death Syndrome (SIDS) remains the leading cause of infant mortality in Western societies. A prior study identified an association between hearing suppression on the newborn hearing test and subsequent death from SIDS. This is the first finding of an abnormality in SIDS cases prior to death. A following ...
Simpson Kathleen Rice - - 2013
To determine potential risks and/or benefits of underwater birth for mother and infant. The PubMed, Cochrane Library, EMBASE, and CINAHL online databases were searched for relevant English language articles related to research about underwater birth published from 1966 to April 2013. Reference lists of articles retrieved were reviewed to identify ...
Graça André M - - 2013
BackgroundReduced supratentorial brain growth has been shown in preterms by term-equivalent age (TEA), but cerebellar growth may be preserved in the absence of supratentorial injury. Our study aimed to compare cerebellar size assessed using cranial ultrasound (cUS) at TEA between preterm infants and term-born controls.Methods:Cerebellar dimensions (including transverse cerebellar diameter ...
Langlois Peter H - - 2013
The objective of this study was to compare results from four statistical approaches to describe the epidemiology of a birth defect. Cases of tracheoesophageal fistula and/or esophageal atresia were selected from the Texas Birth Defects Registry, and live births from Texas birth certificate data. All were delivered in 1999 through ...
Goyal Neera K NK Division of Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA. - - 2013
Home visiting is 1 strategy to improve child health and parenting. Since implementation of home visiting trials 2 decades ago, US preterm births (<37 weeks) have risen by 20%. The objective of this study was to review evidence regarding home visiting and outcomes of preterm infants Searches of Medline, Cumulative ...
Pettit Kate E - - 2013
Abstract Objective: While antenatal corticosteroids reduce the risk of neonatal morbidity and mortality, perhaps the maternal hyperglycemia they produce has other neonatal effects. Thus, we sought to examine the association between antenatal betamethasone exposure and neonatal hypoglycemia and hyperbilirubinemia. Methods: We designed a retrospective cohort study of all preterm deliveries ...
Henriksen Bradley S BS Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah 84132, - - 2013
Deposition of the macular pigment carotenoids lutein and zeaxanthin in the human retina occurs early in life. In this study, we examined the interrelationships of maternal carotenoid status and newborn infant macular pigment levels and systemic carotenoid status. As a secondary measure, we also evaluated the effects of intrauterine growth ...
Asante Kwaku Poku KP Kintampo Health Research Centre, Ghana Health Service, - - 2013
Whether the risk of malaria is increased in infants born to mothers who experience malaria during pregnancy is uncertain.  We investigated malaria incidence among an infant cohort born to 355 primigravidae and 1500 multigravidae with or without placental malaria (PM) in a high malaria transmission area of Ghana. PM was ...
Shakib Julie H - - 2013
To assess pregnancy and birth outcomes in infants born to women who did or did not receive tetanus, diphtheria, acellular pertussis (Tdap) vaccine during pregnancy. Retrospective cohort. Pregnant women 12-45 years of age who received Tdap at Intermountain Healthcare facilities and their infants were identified and compared with mother-infant pairs ...
Bates Melissa L - - 2013
Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, occurs in ∼30% of preterm infants (15,000 per year) and is associated with a clinical history of mechanical ventilation and/or high inspired oxygen at birth. Here, we describe changes in ventilatory control that exist in patients with BPD, including alterations in ...
Dani Carlo - - 2013
Abstract Objective: Maternal diabetes increases the risk of perinatal mortality and morbidity, but the maintenance of antenatal normal glucose serum prevents the majority of neonatal complications. The aim of our study is to compare the metabolomic profile of infants of gestational diabetic mothers (IGDMs) to that of infants of healthy ...
Yau Wai-Ping - - 2013
Previous studies suggested that early pregnancy exposure to specific oral decongestants increases the risks of several birth defects. Using January 1993-January 2010 data from the Slone Epidemiology Center Birth Defects Study, we tested those hypotheses among 12,734 infants with malformations (cases) and 7,606 nonmalformed control infants in the United States ...
Sannia Andrea - - 2013
Intraventricular hemorrhage (IVH) is the most common variety of cerebral hemorrhage and cause of neurologic disabilities in preterm newborns. We evaluated the usefulness of urine Activin A concentrations for the early detection of perinatal IVH. We conducted a case-control study on 100 preterm newborns (20 with IVH and 80 without ...
Colbourn Tim - - 2013
Maternal, perinatal and neonatal mortality remains high in low-income countries. We evaluated community and facility-based interventions to reduce deaths in three districts of Malawi. We evaluated a rural participatory women's group community intervention (CI) and a quality improvement intervention at health centres (FI) via a two-by-two factorial cluster randomized controlled ...
Paquette Alison G - - 2013
The serotonin receptor, HTR2A, exhibits placental expression and function and can be controlled through DNA methylation. The relationship between methylation of HTR2A in the placenta and neurodevelopmental outcomes, evaluated using the NICU Network Neurobehavioral Scales (NNNS), was assessed in newborn infants (n = 444). HTR2A methylation was significantly higher in ...
Tuncer Oguz - - 2013
We compared spectrophotometric analysis of the umbilical cords of infants with meconium aspiration syndrome (MAS) or with meconium-stained amniotic fluid (MSAF) and healthy infants. In a prospective study, 15 infants with MAS and 37 infants with MSAF were enrolled. Twenty healthy infants formed a control group. The absorption peak of ...
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