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Martin Richard M RM School of Social and Community Medicine, University of Bristol, Bristol, UK (R.M.M., R.P., Y.F., G.D.S.); Medical Research Council/University of Bristol Integrated Epidemiology Unit, University of Bristol, Bristol, UK (R.M.M., G.D.S.); National Institute for Health Research, Bristol Biomedical Research Unit in Nutrition, Bristol, UK (R.M.M.); Departments of Pediatrics and of Epidemiology, Biostatistics, and Occupational Health, McGill University Faculty of Medicine, Montreal, Canada (M.S.K.); National Research and Applied Medicine Mother and Child Centre, Minsk, Belarus (K.V., N.B., N.S., N.G.); Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK (T.P.); and Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA (J.T., M.W.G., - - 2014
The duration and exclusivity of breastfeeding in infancy have been inversely associated with future cardiometabolic risk. We investigated the effects of an experimental intervention to promote increased duration of exclusive breastfeeding on cardiometabolic risk factors in childhood. We followed-up children in the Promotion of Breastfeeding Intervention Trial, a cluster-randomized trial ...
Sankararaman Senthilkumar - - 2013
Studies documented that platelet activating factor (PAF) and the enzyme platelet activating factor acetylhydrolase (PAFAH) play a very important role in the pathogenesis of neonatal necrotizing enterocolitis (NEC). In this retrospective, case-controlled pilot study, the authors investigated the prevalence of single nucleotide polymorphisms (Ile198Thr and Ala379Val) of the PAFAH gene. ...
Boskabadi Hassan H Department of Pediatrics, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2013
Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific. We have evaluated serum IL-6, 8 and 10 as potential early diagnostic markers of neonatal infection and their relationship to mortality rate and poor prognosis. Materials and Methods : ...
Summer Suzanne S - - 2013
Sleeping Metabolic Rate (SMR) is used as a proxy for Basal Metabolic Rate in infants, when measurement while awake is not practical. Measuring SMR via indirect calorimetry (IC) can be useful for assessing feeding adequacy especially in compromised neonates. Standard IC equipment, including the hood placed over the head, is ...
Graves Steven W SW Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT. Electronic address: - - 2014
Endogenous digoxin-like factor (EDLF) has been linked to vasoconstriction, altered membrane transport, and apoptosis. Our objective was to determine whether increased EDLF in the cord sera of preterm infants was associated with an increased incidence of necrotizing enterocolitis (NEC). Cord sera from pregnant women enrolled in a randomized trial of ...
Matatyaho-Bullaro Dalit J - - 2013
This study assessed whether specific types of object motion, which predominate in maternal naming to preverbal infants, facilitate word mapping by infants. A total of 60 full-term 8-month-old infants were habituated to two spoken words, /bæf/ and /wem/, synchronous with the handheld motions of a toy dragonfly and a fish ...
Platts-Mills James A JA Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia; Haydom Lutheran Hospital, Haydom, Tanzania; Kilimanjaro Clinical Research Institute, Moshi, Tanzania; Fogarty International Center, National Institutes of Health, Bethesda, - - 2014
Etiologic studies of diarrhea are limited by uneven diagnostic methods and frequent asymptomatic detection of enteropathogens. Polymerase chain reaction-based stool pathogen quantification may help distinguish clinically significant infections. We performed a nested case-control study of diarrhea in infants from a community-based birth cohort in Tanzania. We tested 71 diarrheal samples ...
Hadders-Algra Mijna - - 2013
Successful reaching requires postural control, either by active regulation or by postural support. The present paper reviews literature on typical and atypical development of reaching and postural control during infancy. Typically, reaching movements end in grasping around 4 months of age. Initially, reaches are characterized by large variation, including many trajectory ...
Verspyck Eric - - 2013
To determine if preterm premature rupture of membranes (PPROM) before 24 weeks is an independent risk factor for poor outcome in preterm neonates. A retrospective comparative cohort study was conducted, including viable premature infants born between 25 and 34 weeks gestation. Each preterm case with early PPROM was matched with ...
Kumar Manoj - - 2013
Epidural analgesia is the commonest mode for providing pain relief in labour, with a combination of bupivacaine and fentanyl most often used in practice. To test whether late-preterm and term neonates exposed to opioids in epidural analgesia in labour are more likely to develop respiratory distress in the immediate neonatal ...
Hsu Jen-Fu - - 2013
We aimed to characterize the clinical manifestations and outcomes of patients with Acinetobacter baumannii bacteremia in the neonatal intensive care unit (NICU). All patients with A baumannii bacteremia in our NICU from 2004 to 2010 were reviewed. A matched case-control study was performed by comparing each case of A baumannii ...
Song Dongli - - 2013
Background:Stimulation of the nervous system plays a central role in brain development and neurodevelopmental outcome. Thalamocortical and corticocortical development is diminished in premature infants and correlated to electroencephalography (EEG) progression. The purpose of this study was to determine the effects of orocutaneous stimulation on the modulation of spectral edge frequency, ...
Aikio Outi - - 2013
Abstract Objectives. Persistent ductus arteriosus (PDA) delays the recovery of very preterm infants (VLGA, gestation <32 weeks). Indomethacin/ibuprofen treatment and ligation of PDA have complications. As a prostaglandin synthase inhibitor paracetamol may also promote the closure of ductus arteriosus. We studied retrospectively whether early paracetamol therapy was associated with decreased ...
Feldman Ruth - - 2013
Maternal-newborn contact enhances organization of the infant's physiological systems, including stress reactivity, autonomic functioning, and sleep patterns, and supports maturation of the prefrontal cortex and its ensuing effects on cognitive and behavioral control. Premature birth disrupts brain development and is associated with maternal separation and disturbances of contact-sensitive systems. However, ...
Fiscus Susan A - - 2013
The qualitative Roche HIV-1 DNA Amplicor assay has been used for the past 20 years to diagnose HIV infection in infants and young children, but is being phased out; hence, alternative assays must be found. The Gen-Probe Aptima qualitative HIV-1 RNA assay is currently the only FDA cleared HIV-1 nucleic ...
Li Qian Q Department of Epidemiology, Harvard School of Public Health, Boston, - - 2013
Several studies have reported an association between use of specific antihistamines in early pregnancy and certain specific birth defects. To test 16 previously hypothesized associations between specific antihistamines and specific birth defects, and to identify possible new associations. We used 1998-2010 data from the Slone Epidemiology Center Birth Defects Study, ...
Martinez-Biarge Miriam - - 2013
To determine whether antepartum factors alone, intrapartum factors alone, or both in combination, are associated with term neonatal hypoxic-ischemic encephalopathy (HIE).METHODS:A total of 405 infants ≥35 weeks' gestation with early encephalopathy, born between 1992 and 2007, were compared with 239 neurologically normal infants born between 1996 and 1997. All cases ...
Allen T - - 2013
Sudden Infant Death Syndrome (SIDS) remains the leading cause of infant mortality in Western societies. A prior study identified an association between hearing suppression on the newborn hearing test and subsequent death from SIDS. This is the first finding of an abnormality in SIDS cases prior to death. A following ...
Simpson Kathleen Rice - - 2013
To determine potential risks and/or benefits of underwater birth for mother and infant. The PubMed, Cochrane Library, EMBASE, and CINAHL online databases were searched for relevant English language articles related to research about underwater birth published from 1966 to April 2013. Reference lists of articles retrieved were reviewed to identify ...
Graça André M - - 2013
BackgroundReduced supratentorial brain growth has been shown in preterms by term-equivalent age (TEA), but cerebellar growth may be preserved in the absence of supratentorial injury. Our study aimed to compare cerebellar size assessed using cranial ultrasound (cUS) at TEA between preterm infants and term-born controls.Methods:Cerebellar dimensions (including transverse cerebellar diameter ...
Langlois Peter H - - 2013
The objective of this study was to compare results from four statistical approaches to describe the epidemiology of a birth defect. Cases of tracheoesophageal fistula and/or esophageal atresia were selected from the Texas Birth Defects Registry, and live births from Texas birth certificate data. All were delivered in 1999 through ...
Goyal Neera K NK Division of Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA. - - 2013
Home visiting is 1 strategy to improve child health and parenting. Since implementation of home visiting trials 2 decades ago, US preterm births (<37 weeks) have risen by 20%. The objective of this study was to review evidence regarding home visiting and outcomes of preterm infants Searches of Medline, Cumulative ...
Pettit Kate E - - 2013
Abstract Objective: While antenatal corticosteroids reduce the risk of neonatal morbidity and mortality, perhaps the maternal hyperglycemia they produce has other neonatal effects. Thus, we sought to examine the association between antenatal betamethasone exposure and neonatal hypoglycemia and hyperbilirubinemia. Methods: We designed a retrospective cohort study of all preterm deliveries ...
Henriksen Bradley S BS Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah 84132, - - 2013
Deposition of the macular pigment carotenoids lutein and zeaxanthin in the human retina occurs early in life. In this study, we examined the interrelationships of maternal carotenoid status and newborn infant macular pigment levels and systemic carotenoid status. As a secondary measure, we also evaluated the effects of intrauterine growth ...
Asante Kwaku Poku KP Kintampo Health Research Centre, Ghana Health Service, - - 2013
Whether the risk of malaria is increased in infants born to mothers who experience malaria during pregnancy is uncertain.  We investigated malaria incidence among an infant cohort born to 355 primigravidae and 1500 multigravidae with or without placental malaria (PM) in a high malaria transmission area of Ghana. PM was ...
Shakib Julie H JH Department of Pediatrics, University of Utah, Salt Lake City, UT. Electronic address: - - 2013
To assess pregnancy and birth outcomes in infants born to women who did or did not receive tetanus, diphtheria, acellular pertussis (Tdap) vaccine during pregnancy. Retrospective cohort. Pregnant women 12-45 years of age who received Tdap at Intermountain Healthcare facilities and their infants were identified and compared with mother-infant pairs ...
Bates Melissa L - - 2013
Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, occurs in ∼30% of preterm infants (15,000 per year) and is associated with a clinical history of mechanical ventilation and/or high inspired oxygen at birth. Here, we describe changes in ventilatory control that exist in patients with BPD, including alterations in ...
Dani Carlo - - 2013
Abstract Objective: Maternal diabetes increases the risk of perinatal mortality and morbidity, but the maintenance of antenatal normal glucose serum prevents the majority of neonatal complications. The aim of our study is to compare the metabolomic profile of infants of gestational diabetic mothers (IGDMs) to that of infants of healthy ...
Yau Wai-Ping WP Department of Epidemiology, Harvard School of Public Health, Harvard University, Boston, MA, - - 2013
Previous studies suggested that early pregnancy exposure to specific oral decongestants increases the risks of several birth defects. Using January 1993-January 2010 data from the Slone Epidemiology Center Birth Defects Study, we tested those hypotheses among 12,734 infants with malformations (cases) and 7,606 nonmalformed control infants in the United States ...
Sannia Andrea - - 2013
Intraventricular hemorrhage (IVH) is the most common variety of cerebral hemorrhage and cause of neurologic disabilities in preterm newborns. We evaluated the usefulness of urine Activin A concentrations for the early detection of perinatal IVH. We conducted a case-control study on 100 preterm newborns (20 with IVH and 80 without ...
Colbourn Tim - - 2013
Maternal, perinatal and neonatal mortality remains high in low-income countries. We evaluated community and facility-based interventions to reduce deaths in three districts of Malawi. We evaluated a rural participatory women's group community intervention (CI) and a quality improvement intervention at health centres (FI) via a two-by-two factorial cluster randomized controlled ...
Paquette Alison G AG Department of Pharmacology and Toxicology; Geisel School of Medicine at Dartmouth; Dartmouth, NH - - 2013
The serotonin receptor, HTR2A, exhibits placental expression and function and can be controlled through DNA methylation. The relationship between methylation of HTR2A in the placenta and neurodevelopmental outcomes, evaluated using the NICU Network Neurobehavioral Scales (NNNS), was assessed in newborn infants (n = 444). HTR2A methylation was significantly higher in ...
Tuncer Oguz - - 2013
We compared spectrophotometric analysis of the umbilical cords of infants with meconium aspiration syndrome (MAS) or with meconium-stained amniotic fluid (MSAF) and healthy infants. In a prospective study, 15 infants with MAS and 37 infants with MSAF were enrolled. Twenty healthy infants formed a control group. The absorption peak of ...
Guzoglu Nilufer - - 2013
Abstract Background: Hemodynamically significant patent ductus arteriosus (PDA) is a common problem in preterm infants which often causes significant morbidities. Although PDA induces alterations in various tissue perfusion, there is scarce information about the effect of oral ibuprofen on hemodynamics of regional tissues. Objective: To investigate, using near-infrared spectroscopy, the ...
Parsons C E - - 2013
Infant vocalisations are amongst the most biologically salient sounds in the environment and can draw the listener to the infant rapidly in both times of distress and joy. A region of the midbrain, the periaqueductal gray (PAG), has long been implicated in the control of urgent, survival-related behaviours. To test ...
Simeone Regina M - - 2013
BACKGROUND: Congenital hydrocephalus is a condition characterized by accumulation of cerebrospinal fluid in the ventricles of the brain. Prenatal infections are risk factors for some birth defects. This pilot study investigated whether residual dried blood spots (DBS) could be used to assess infections as risk factors for birth defects by ...
Mohammed Amal H - - 2013
BACKGROUND: Malaria, which frequently occurs in pregnant women in the tropics, is a leading cause of maternal anaemia and low birth weight (LBW) in infants. Few data exist concerning malaria infections that are present at submicroscopic levels during pregnancy and their LBW delivery in babies. METHODS: A case--control study (87 ...
Wan-Huen P - - 2013
Objective:To determine whether a temporal association exists between antecedent packed red blood cell (PRBC) transfusions and necrotizing enterocolitis (NEC) in premature infants.Study Design:This case-control study included inborn infants from a single center who developed NEC during a 2-year period. For every NEC infant, two matched controls from the same period ...
Amirthalingam Gayatri - - 2013
The UK is currently in the midst of a large outbreak of pertussis, with the highest morbidity and mortality occurring in young unimmunised infants. This review considers the potential strategies to optimise control of pertussis in infants, including vaccination of (1) adolescents, (2) close household contacts of newborn infants (cocooning), ...
Rachwani Jaya J Department of Human Physiology and Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA. - - 2013
This study explored the influence of an external support at the thoracic and pelvic level of the trunk on the success of reaching, postural stability and reaching kinematics while infants reached for a toy. Seventeen infants (4-6 months) were clustered into two groups according to their trunk control assessed with the ...
Abdelmoktader Ahmed Mahmoud - - 2013
Although the prevention of the neuropsychological consequences of congenital hypothyroidism (CH) through the use of replacement therapy represents an important public health success, knowledge about the modifiable risk factors could reduce the number of infants affected by this disease. This study was carried out to identify risk factors for CH ...
Hogan Cathy C SSM Cardinal Glennon Children's Medical Center, St. Louis, - - 2014
Though the Back to Sleep Campaign that began in 1994 caused an overall decrease in sudden infant death syndrome (SIDS) rates, racial disparity has continued to increase in St. Louis. Though researchers have analyzed and described various sociodemographic characteristics of SIDS and infant deaths by unintentional suffocation in St. Louis, ...
Starikov Roman - - 2013
This study aimed to determine whether poor glycemic control in early pregnancy is associated with an increased risk of congenital heart disease (CHD) for infants of women with preexisting diabetes. A retrospective review examined two tertiary care centers of diabetic pregnancies that recorded early hemoglobin A1c (HbA1c) values (<20 weeks). The ...
Saleemi M S - - 2013
Objective:To investigate myocardial velocities in anemic very low-birth weight (VLBW) preterm infants, pre and post red blood cells transfusion using tissue Doppler imaging echocardiography.Study design:Forty-eight VLBW preterm infants34 weeks and>2 weeks old were prospectively divided: Transfused symptomatic infants (Hematocrit (Hct)<0.30 (n=32)) and non transfused asymptomatic controls (control 1, Hct >0.30 ...
Abdullahi Hala - - 2013
BACKGROUND: Cerebral palsy (CP) is a major cause of childhood disability. There are various maternal and neonatal predictors associated with the development of CP, and they are variable across different populations. This case¿control study was designed to investigate maternal and neonatal predictors of CP at Khartoum pediatric neurology clinics. Data ...
Walker Karen - - 2013
AIM: To compare the developmental outcome of infants with oesophageal atresia with or without trachea-oesophageal fistula (OA/TOF) who underwent surgery in early infancy with healthy control infants in New South Wales, Australia. METHODS: Infants diagnosed with OA/TOF requiring surgical intervention were enrolled prospectively between 1 August 2006 and the 31 ...
Lima-Alvarez Carolina Daniel de - - 2013
ABSTRACT The authors investigated the effects of postural manipulation on head movement control in infants from birth to 4 months of age. Eighteen full-term infants were presented with a card, which was moved from side to side before their eyes in 3 positions: unsupported supine, supported supine, and supported reclined. ...
Jagannathan N - - 2013
We describe a four-step method for fibreoptic-guided, rapid-sequence tracheal intubation through the air-Q(®) intubating laryngeal airway in infants with severe airway obstruction. Our step-wise process provides an organised and controlled approach to safely securing the airway.
Sahin Orcun - - 2013
: The purpose of this study is to evaluate if there is any relationship between consanguineous marriages and idiopathic congenital talipes equinovarus (CTEV). : A case-control study on CTEV screening was conducted in a rural eastern city of Turkey between 2009 and 2011 and a total of 28 cases (infants ...
Horne Rosemary S C - - 2013
During the first year of life and particularly the first 6 months autonomic control of the cardio-respiratory system is still undergoing maturation and infants are at risk of cardio-respiratory instability. These instabilities are most marked during sleep, which is important as infants spend the majority of each 24hours in sleep. ...
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