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Arnon Shmuel S Department of Neonatology, Meir Medical Center, Kfar Saba, Israel affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Kangaroo care (KC) and maternal singing benefit preterm infants and we investigated whether combining these benefitted infants and mothers. A prospective randomised, within-subject, crossover, repeated-measures study design was used, with participants acting as their own controls. We evaluated the heart rate variability (HRV) of stable preterm infants receiving KC, with ...
Caldwell Curtis D - - 2014
Many studies suggest the answer to this question is yes. A recent meta-analysis and updated systematic review of 11 randomized controlled trials involving 2,176 infants confirmed the benefits of probiotic supplementation. The incidence of necrotizing enterocolitis (NEC) in this study was reduced by 30 percent.1 The authors concluded that probiotics ...
Feinberg Mark E ME Prevention Research Center, Penn State University, 314 Biobehavioral Health, University Park, PA, 16802, USA, - - 2014
Although maternal stress and depression have been linked to adverse birth outcomes (ABOs), few studies have investigated preventive interventions targeting maternal mental health as a means of reducing ABOs. This randomized controlled study examines the impact of Family Foundations (FF)-a transition to parenthood program for couples focused on promoting coparenting ...
Counts Jennifer L JL Procter & Gamble, Cincinnati, OH, USA - - 2014
Disposable diapers today employ dramatically better fitting, less bulky, and more environmentally friendly features that deliver better performance and help provide protection for infant skin. Continuous innovations in technology and materials have resulted in new generations of disposable diapers that provide extended dryness and reduced leakage. Driven by studies on ...
Helmes C Tucker CT Center for Baby and Adult Hygiene Products, Washington, DC, - - 2014
Absorbency effectiveness in diapers has improved significantly in recent years with the advent of new ingredient combinations and advanced design features. With these features, many leading products maintain their dryness performance overnight. Considering the importance of holding liquid away from the skin, ongoing research in diaper construction focuses on strategies ...
Kiran Sai S Department of Pediatrics, Fernandez Hospital, Hyderabad, Andhra Pradesh, 500029, - - 2014
To evaluate the need for up-transfer after starting of nasal continuous positive airway pressure (n-CPAP) services in a Level II special newborn care unit (SNCU). Five hundred fifty infants admitted to Level II SNCU, 252 infants during one year prior to introduction of n-CPAP (retrospective data from case records and ...
Yilmaz Gonca G Department of Social and Developmental Pediatrics, Dr. Sami Ulus Children and Maternity Training Hospital, Birlik Mah. Kahire Cad. 451 Sokak, Zirvekent Mimoza Sitesi A2 Blok, No 54, Çankaya, Ankara, Turkey, - - 2014
Although the analgesic effect of sucrose on newborns is well established, little is known about whether these solutions are effective in reducing procedural pain in infants beyond the newborn period. The purpose of this study was to determine the effect of sucrose solution given orally on infant crying times and ...
Lohmann Pablo P Division of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, - - 2014
Background:Bronchopulmonary dysplasia (BPD) is associated with perinatal inflammatory triggers. Methods targeting bacterial rRNA may improve detection of microbial colonization in premature infants. Hypothesis: Respiratory microbiota differs between preterm infants who develop BPD and those unaffected, and correlates with inflammatory mediator concentrations.Methods:Twenty-five infants, born ≤32 weeks of gestation and intubated in ...
Lambon-Quayefio Monica P MP Economics, Clark University, 950 Main Street, Worcester, MA, 01610, USA, - - 2014
Many Sub-Saharan African countries may not achieve the Millennium Development goal of reducing child mortality by 2015 partly due to the stalled reduction in neonatal deaths, which constitute about 60 % of infant deaths. Although many studies have emphasized the importance of accessible maternal healthcare as a means of reducing maternal ...
- - 2014
A GROWING gap between the rich and poor and insufficient targeted health policies to reduce mortality mean that children in the UK have a higher risk of dying prematurely than those living in other Western European countries.
Zhang Peiyin P Department of Pediatrics, Centre Mère-Enfant, - - 2014
Omega-3 long chain polyunsaturated fatty acid (LCPUFA) exposure can be associated with reduced neonatal morbidities. We systematically review the evidence for the benefits of omega-3 LCPUFAs for reducing neonatal morbidities in extremely preterm infants.METHODS: Data sources were PubMed, Embase, Center for Reviews and Dissemination, and the Cochrane Register of Controlled ...
Popova Antonia P AP University of Michigan Medical - - 2014
Animal studies have shown that platelet-derived growth factor (PDGF) signaling is required for normal alveolarization. Changes in PDGF receptor (PDGFR) expression in infants with bronchopulmonary dysplasia (BPD), a disease of hypoalveolarization, have not been examined. We hypothesized that PDGFR expression is reduced in neonatal lung mesenchymal stromal cells (MSCs) from ...
Khan Jehangir J Faculty of Medicine, Lund University, Jan Waldenströms gata, 205 02, Malmo, Sweden, - - 2014
The purpose of this study was to review the evidence on the effect of initiation of breastfeeding early after birth and of exclusive breastfeeding during the first month in reducing neonatal mortality and morbidity. We searched Cochrane and PubMed databases for all available papers addressing our review questions and identified ...
Smith Cl C Neonatal Unit, Simpson Centre for Reproductive Health, Royal Infirmary of Edinburgh, Edinburgh, - - 2014
Late onset Infection (LOI, infection after day 3 of postnatal life) is associated with neurodevelopmental impairment, bronchopulmonary dysplasia (BPD) and death among VLBW infants. The incidence of LOI varies widely between neonatal units and the optimal strategy for reducing LOI is uncertain. We aimed to evaluate the effect of a ...
Griffin Mj M Women's Health Academic Centre, King's College London, London, - - 2014
: The SGA infant is at increased risk of short and long-term health complications. Identifying the SGA fetus remains challenging. Placental insufficiency contributes to pathogenesis and it has been proposed that markers of placental function such as PlGF may improve prediction. PELICAN FGR, a large multicentre, prospective observational study measuring ...
Thankappen Ra R Luton and Dunstable Hospital, Luton, - - 2014
Unexpected term admissions represent a significant percentage of NICU admissions and are major contributors to work load. We audited all infants admitted over 3 months with the aim to Determine the pattern of potentially avoidable admissions. Determine the degree of support these infants required. Retrospective review of admissions >36+6/40 gestation ...
Krief Sabrina S UMR 7206 CNRS/MNHN/P7, Ecoathropologie et ethnobiologie, CP 135, Museum national d'histoire naturelle, Paris, France; Projet pour la conservation des grands singes (PCGS), UWA Sebitoli Station, Kibale National Park, Fort Portal, - - 2014
At least 10% of the Sebitoli chimpanzee community of the Kibale National Park (Uganda) present a characteristic facial phenotype with flattened nose, reduced nostrils, and concave mid-face. Affected individuals do not present skin lesions, and also young infants are affected. We suggest, therefore, a congenital origin of this defect.
Pergialiotis Vasileios V Laboratory of Experimental Surgery and Surgical Research N.S. Christeas, Athens University, Medical - - 2014
Abstract Objective: To evaluate the effectiveness double cervical cerclage in reducing antenatal complications and improve perinatal outcomes. Methods: We searched Medline, Scopus, Clinicaltrials.org, The Cochrane Central Register of Controlled Trials and Google Scholar search engines. Results: Six studies were included that involved 880 women. Double cerclage was significantly superior to ...
Jakus Zoltán Z Department of Medicine, 2 Cardiovascular Institute, and 3 Department of Dermatology, University of Pennsylvania, Philadelphia, PA - - 2014
Mammals must inflate their lungs and breathe within minutes of birth to survive. A key regulator of neonatal lung inflation is pulmonary surfactant, a lipoprotein complex which increases lung compliance by reducing alveolar surface tension (Morgan, 1971). Whether other developmental processes also alter lung mechanics in preparation for birth is ...
Stevens Jeni J School of Nursing and Midwifery, University of Western Sydney, Penrith, New South Wales, - - 2014
The World Health Organization and the United Nations International Children's Emergency Fund recommends that mothers and newborns have skin-to-skin contact immediately after a vaginal birth, and as soon as the mother is alert and responsive after a Caesarean section. Skin-to-skin contact can be defined as placing a naked infant onto ...
Boyce Rogely W RW Amgen Inc.,One Amgen Center Drive, MS 29-2-A, Thousand Oaks, CA 91320, USA. Electronic address: - - 2014
RANKL is a key regulator of bone resorption and osteoclastogenesis. Denosumab is a fully human IgG2 monoclonal antibody that inhibits bone resorption by binding and inhibiting the activity of RANKL. To determine the effects of denosumab on pre-and postnatal skeletal growth and development, subcutaneous injections of 0 (control) or 50mg/kg/month ...
Loots Clara C *Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, AMC, Amsterdam, The Netherlands †School of Medicine, Flinders University, Adelaide, Australia ‡Pediatric Gastroenterology, Royal Children's Hospital Brisbane, Australia §Neonatal Intensive Care Unit, Women's and Children's Health Network, Australia ||North Western Academic Centre University of Melbourne, Australia ¶School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia #Gastroenterology Unit, Women's and Children's Health Network, Adelaide, - - 2014
Proton pump inhibitors (PPIs) reduce acid gastro-esophageal reflux (GER) and esophageal acid exposure in infants. However, they do not reduce total GER nor symptoms attributed to GER. Reflux is reduced in the left lateral position (LLP). We hypothesize that the effect of LLP in combination with acid suppression is most ...
Ghavam Sarvin - - 2014
Risks and benefits of increasing placental transfusion in extremely preterm infants (extremely low birthweight [ELBW], <1000 g) are ill defined. We performed a meta-analysis to compare long- and short-term outcomes of ELBW infants in trials of enhanced placental transfusion regimens. We conducted a meta-analysis of randomized controlled trials (RCTs) of ...
Alsafadi Tariq Rushdi Mohieldeen TR Department of Pediatric, Neonatal Intensive Care Unit, Aziziah Maternity and Children Hospital, Jeddah, Kingdom of Saudi - - 2014
Polycythemia (PC) is defined as venous hematocrit (hct) ≥65%.( ) Its incidence is high among certain risk factors (RFs). Its management is controversy. TO DETERMINE: (1) The incidence of PC in our neonatal intensive care unit (NICU). (2) Most common RF, symptoms, and laboratory abnormalities (LA) associated with PC and their ...
Bartholomew Julie J Department of Neonatology, Jewish General Hospital, McGill University, Montreal, Quebec, - - 2014
Antenatal and postnatal corticosteroids play an extremely important role in the management of premature infants. The antenatal administration of steroids has been universally implemented. They have not only been shown to reduce the incidence and severity of respiratory distress syndrome (RDS), but also have an impact on the incidence of ...
Lee A-R AR Department of Anesthesiology and Pain Medicine, Jeju National University Hospital, Jeju Special Self-governing Province, - - 2014
Catheterisation of the internal jugular vein (IJV) can be difficult in infants. We aimed to evaluate whether a simple manoeuvre, a slight caudo-lateral traction of the ipsilateral arm (CLTIA), could decrease the head rotation-induced overlap of the IJV to the carotid artery (CA) in infants. Twenty-five infants were included. The ...
Harsløf Laurine B S LB Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, 1958, Frederiksberg C, - - 2014
Long-chain n-3 fatty acids (n-3 LCPUFA) improve blood pressure (BP) and lipid profile in adults and improve insulin sensitivity in rodents. We have previously shown that n-3 LCPUFA reduces BP and plasma triacylglycerol (TAG) in infants. Few studies have found effects on glucose homeostasis in humans. We explored possible effect ...
Li Zhiwen Z Institute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, - - 2014
Folic acid-containing multivitamins have been associated with a reduced risk of preterm birth. We examined whether periconceptional use of folic acid alone reduced this risk. Data were derived from a large population-based cohort study conducted in China to evaluate the prevention of neural tube defects with folic acid supplementation. The ...
Gonzales Gustavo F GF Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Honorio Delgado 430, Lima 31, Peru, - - 2014
To determine if correction of cut-offs of haemoglobin levels to define anaemia at high altitudes affects rates of adverse perinatal outcomes. Data were obtained from 161,909 mothers and newborns whose births occurred between 1,000 and 4,500 m above sea level (masl). Anaemia was defined with or without correction of haemoglobin (Hb) ...
Vandenplas Y Y UZ Brussel, Department of Paediatrics, Vrije Universiteit Brussel, Brussels, - - 2014
Cow's milk protein allergy (CMPA) is treated using an elimination diet with an extensive protein hydrolysate. We explored whether a thickened or non-thickened version was best for infants with suspected CMPA, which commonly causes regurgitation/vomiting. Diagnosis of CMPA was based on a positive challenge test. We compared the efficacy of ...
Sherman Michael P MP aDepartment of Child Health bDepartment of Molecular Microbiology and Immunology, School of Medicine cSinclair School of Nursing, University of Missouri, Columbia, Missouri dDivision of Neonatal Medicine, Nemours Children's Hospital, Orlando, Florida, - - 2014
There is an intense interest among neonatal caregivers as to whether lactoferrin given enterally may reduce the incidence of necrotizing enterocolitis in preterm infants. This review presents scientific and clinical evidence that lactoferrin alleviates or prevents this life-threatening disease. Preclinical studies in neonatal rats showed that lactoferrin given orally before ...
McAdams Ryan M RM Department of Pediatrics, University of Washington, Seattle, - - 2014
Immediate umbilical cord clamping after delivery is routine in the United States despite little evidence to support this practice. Numerous trials in both term and preterm neonates have demonstrated the safety and benefit of delayed cord clamping. In premature neonates, delayed cord clamping has been shown to stabilize transitional circulation, ...
Kandasamy Y Y 1 Department of Neonatology, The Townsville Hospital, Queensland 4814, - - 2014
Rates of chronic kidney disease (CKD) among Indigenous groups in Australia exceed non-Indigenous rates eight-fold. Using kidney volume as a surrogate for nephron number, we carried out a study to determine if Indigenous neonates have a smaller kidney volume (and thus a reduced nephron number) from birth compared with non-Indigenous ...
Thach B T BT Department of Pediatrics, Washington University School of Medicine, Kirkwood, MO, - - 2014
Objective:Our aim was to evaluate programs promoting bed sharing on maternity wards and determining ways to reduce these risks.Study Design:Members of the National Association of Medical Examiners were contacted requesting information on deaths of healthy infants while bed sharing on maternity wards.Result:Fifteen deaths and three near deaths are reported. One ...
Janvier Annie A Centre Hospitalier Universitaire Sainte Justine, Montréal, Quebec, - - 2014
To determine whether routine probiotic administration to very preterm infants would reduce the incidence of necrotizing enterocolitis (NEC) without adverse consequences. Since the end of July 2011, we have administered a probiotic mixture to all admitted infants of <32 weeks' gestation. We give 0.5 g of a mixture of 4 ...
Thust Stefanie Catherine SC Department of Neuroradiology, The National Hospital for Neurology and Neurosurgery, London, - - 2014
An 11-week-old baby was brought to the paediatric emergency department by his mother with a 2-day history of inconsolable crying. On examination, clinical features of macrocephaly, separated sutures and 'sunsetting' of the eyes were noted. Abnormal head circumference measurements had been obtained on several occasions since birth, but were not ...
Bhutta Zulfiqar A ZA Division of Women and Child Health, The Aga Khan University, Karachi, - - 2014
The global burden of undernutrition remains high with little evidence of change in many countries. We reviewed the evidence of the potential nutritional interventions and estimated their effect on nutrition-related outcomes of women and children. Among the maternal interventions, daily iron supplementation results in a 69% reduction in incidence of ...
Roxby Alison C AC Department of Medicine, University of Washington, Seattle, Washington, United States of - - 2014
Studies in HIV-1-infected infants and HIV-1-exposed, uninfected infants link early cytomegalovirus (CMV) acquisition with growth delay and cognitive impairment. We investigated maternal valacyclovir to delay infant acquisition of CMV. Pregnant women with HIV-1, HSV-2 and CD4 count >250 cells/µl were randomized at 34 weeks gestation to 500 mg twice-daily valacyclovir ...
Gizaw Muluken M Department of Preventive Medicine, School of Public Health, College of Health Sciences Addis Ababa University, Addis Ababa, Ethiopia. - - 2014
Child mortality is an important indicator of a country's developmental status. Neonatal mortality and stillbirth shared a higher proportion of child deaths. However, in developing countries where there is no civil registration and most deliveries occur at home, it is difficult to measure the magnitude of neonatal mortality. Data from ...
Yaya Yaliso Y Centre for International Health, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway; Arba Minch College of Health Sciences, Arba Minch, - - 2014
Ethiopia has achieved the fourth Millennium Development Goal by reducing under 5 mortality. Nevertheless, there are challenges in reducing maternal and neonatal mortality. The aim of this study was to estimate maternal and neonatal mortality and the socio-economic inequalities of these mortalities in rural south-west Ethiopia. We visited and enumerated ...
Lista G G "V. Buzzi" Ospedale dei Bambini Azienda ICP, Milano (Italy). - - 2014
Surfactant administration in spontaneous breathing with N-CPAP seems to be a promising approach in the management of neonatal RDS. Both recent RCTs and single centre experience have shown feasibility and good respiratory outcomes with this approach even in extremely preterm infants with respiratory failure. The results of these studies seem ...
Polin Richard A - - 2013
Respiratory failure secondary to surfactant deficiency is a major cause of morbidity and mortality in preterm infants. Surfactant therapy substantially reduces mortality and respiratory morbidity for this population. Secondary surfactant deficiency also contributes to acute respiratory morbidity in late-preterm and term neonates with meconium aspiration syndrome, pneumonia/sepsis, and perhaps pulmonary ...
Paudel Deepak - - 2013
Nepal has made substantial progress in reducing under-five mortality and is on track to achieve Millennium Development Goal 4, but advances in neonatal health are less encouraging. The objectives of this study were to assess relative and absolute inequalities in neonatal mortality over time, and to review experience with major ...
Miyazaki Ken - - 2013
To evaluate the effectiveness of antenatal corticosteroids (AC) therapy on outcomes of very low birthweight infants with histologic chorioamnionitis. We performed a retrospective analysis of 10,935 single infants born at a gestational age between 22 + 0 and 33 + 6 weeks and birth weight <1,500 g. Clinical data were obtained from the Neonatal Research Network ...
Wapner Ronald J - - 2013
Antenatal corticosteroids have been proven to accelerate fetal lung development and reduce neonatal morbidity and mortality when given between 28 and 34 weeks of gestation. However, there is only limited research to guide their use in the periviable period (22-26 weeks). Laboratory studies suggest that it is biologically plausible for ...
Donoghue Deborah - - 2013
To identify risk factors for preterm birth and determine if these vary by degree of prematurity. We used data from the state-wide mandatory surveillance system for all births in New South Wales, limiting analysis to the 836,292 live born, singleton infants without known birth anomaly born from 1994 to 2004 ...
Jacobs Susan E - - 2013
BACKGROUND AND OBJECTIVE:Late-onset sepsis frequently complicates prematurity, contributing to morbidity and mortality. Probiotics may reduce mortality and necrotizing enterocolitis (NEC) in preterm infants, with unclear effect on late-onset sepsis. This study aimed to determine the effect of administering a specific combination of probiotics to very preterm infants on culture-proven late-onset ...
Belizán Jose M - - 2013
Premature birth is the world's leading cause of neonatal mortality with worldwide estimates indicating 11.1% of all live births were preterm in 2010. Preterm birth rates are increasing in most countries with continual differences in survival rates amongst rich and poor countries. Preterm birth is currently an important unresolved global ...
de Almeida Maria Fernanda Branco - - 2013
To evaluate intervention practices associated with hypothermia at both 5 minutes after birth and at neonatal intensive care unit (NICU) admission and to determine whether hypothermia at NICU admission is associated with early neonatal death in preterm infants. This prospective cohort included 1764 inborn neonates of 22-33 weeks without malformations ...
Williams L Alison - - 2013
The review examines whether mode of feeding is associated with risk of hospitalisation for illness during infancy in developed countries. Databases were searched for published studies that included the terms "infant feeding" and "hospitalisation". Six studies were included. Breastfeeding was associated with a reduced risk of hospitalisation and adjusted analyses ...
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