Search Results
Results 251 - 300 of 1869
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Weiss William J - - 2012
The Penn State Infant Ventricular Assist Device (VAD) is a 12-14 ml stroke volume pneumatically actuated pump, with custom Björk-Shiley monostrut valves, developed under the National Heart, Lung, and Blood Institute Pediatric Circulatory Support program. In this report, we describe the seven most recent chronic animal studies of the Infant ...
Bamat Nicolas - - 2012
Conventional mechanical ventilation (CMV) of neonates has been used as a treatment of respiratory failure for over 30 years. While CMV facilitates gas exchange, it may simultaneously damage the lung. Positive end expiratory pressure (PEEP) has received less attention than other ventilation parameters when considering this balance of benefit and ...
Brehmer Felix - - 2012
Intrauterine infection and inflammation are major reasons for preterm birth. The switch from placenta-mediated to lung-mediated oxygen supply during birth is associated with a sudden rise of tissue oxygen tension that amounts to relative hyperoxia in preterm infants. Both infection/inflammation and hyperoxia have been shown to be involved in brain ...
Hill Kenneth - - 2012
Monitoring development indicators has become a central interest of international agencies and countries for tracking progress towards the Millennium Development Goals. In this review, which also provides an introduction to a collection of articles, we describe the methodology used by the United Nations Inter-agency Group for Child Mortality Estimation to ...
Ashish K C - - 2012
Reducing neonatal death has been an emerging challenge in low and middle income countries in the past decade. The development of the low cost interventions and their effective delivery are needed to reduce deaths from birth asphyxia. This study will assess the impact of a simplified neonatal resuscitation protocol provided ...
Bennet Laura - - 2012
Fetuses at risk of premature delivery are now routinely exposed to maternal treatment with synthetic glucocorticoids. In randomized clinical trials, these substantially reduce acute neonatal systemic morbidity, and mortality, after premature birth and reduce intraventricular hemorrhage. However, the overall neurodevelopmental impact is surprisingly unclear; worryingly, postnatal glucocorticoids are consistently associated ...
Jadcherla Sudarshan R - - 2012
In neonatal intensive care unit infants referred for home-tube feeding methods, we evaluated the effect of an innovative diagnostic and management approach on feeding outcomes at discharge and 1 year, by comparing data from historical controls; we hypothesized that clinical and aerodigestive motility characteristics at evaluation were predictive of feeding ...
Lauzon-Guillain Blandine de Bd Medical Research Council Epidemiology Unit, Cambridge, United - - 2012
To examine the relationship between breastfeeding and maternally-rated infant temperament at age 3 months, 316 infants in the prospective Cambridge Baby Growth Study, UK had infant temperament assessed at age 3 months by mothers using the Revised Infant Behavior Questionnaire, which produces scores for three main dimensions of temperament derived ...
Seaton Sarah E SE Department of Health Sciences, University of Leicester, Leicester, - - 2012
To assess time trends in socioeconomic inequalities in overall and cause-specific stillbirth rates in England. Population-based retrospective study. England. Stillbirths occurring among singleton infants born between 1 January 2000 and 31 December 2007. Cause-specific stillbirth rate per 10 000 births by deprivation tenth and year of birth. Deprivation measured using the ...
Likwela Joris L - - 2011
Objective  To assess the effect of intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) on birth weight in sites with varying degrees of drug resistance. Methods  Birth weight data from three regions in Democratic Republic of Congo with varying degrees of sulfadoxine-pyrimethamine (SP) resistance (1.6% in Mikalayi, 21.7% in Kisangani and 60.6% ...
Kang Huining - - 2012
Gene expression profiling was performed on 97 cases of infant ALL from Children's Oncology Group Trial P9407. Statistical modeling of an outcome predictor revealed 3 genes highly predictive of event-free survival (EFS), beyond age and MLL status: FLT3, IRX2, and TACC2. Low FLT3 expression was found in a group of ...
van Heugten Marieke - - 2011
PURPOSE: To examine the possibility that early signal-to-word form mapping capabilities are robust enough to handle substantial indexical variation in the realization of words. METHOD: 7.5-month-olds were tested using the Headturn Preference Procedure. Half of the infants were exposed to words embedded in passages spoken by their mother and tested ...
Van Kooij Britt J M - - 2011
Aim  To assess the relation between cerebellar volume and spectroscopy at term equivalent age, and neurodevelopment at 24 months corrected age in preterm infants. Methods  Magnetic resonance imaging of the brain was performed around term equivalent age in 112 preterm infants (mean gestational age 28wks 3d [SD 1wk 5d]; birthweight 1129g ...
Hahné Susan - - 2011
BACKGROUND: In the Netherlands, different hepatitis B vaccination schedules have been used for children born to HBV-infected mothers. All schedules included a birth dose of hepatitis B immunoglobuline (HBIg). We assessed determinants of perinatal HBV transmission and determinants of anti-HBs titers in infants born to HBsAg positive mothers. METHODS: We ...
Garcia Silvia - - 2011
INTRODUCTION: Febrile infants less than 3 months of age have a greater risk for serious bacterial infection (SBI). The risk is inversely correlated with age. Most protocols recommend admitting to hospital all febrile infants less than 28 days of age. However, as the prevalence of SBI is not homogenous in ...
Cohen Engler Anat - - 2012
Melatonin is secreted during the night in adults but not in infants. It has a hypnotic effect as well as a relaxing effect on the smooth muscle of the gastrointestinal tract. It is plausible that breast milk, which consists of melatonin, may have an effect on improving infants' sleep and ...
Murthy Vadivelam - - 2012
Data on the effects of a prolonged inflation time during the resuscitation of very prematurely born infants are limited; one study showed no effect, and in another, although lower bronchopulmonary dysplasia (BPD) rates were seen, that effect could have been due to the prolonged inflation time, the positive end expiratory ...
Paes B - - 2012
Palivizumab utilization, compliance, and outcomes were examined in infants with preexisting medical diseases within the Canadian Registry Database (CARESS) to aid in developing guidelines for potential "at-risk" infants in the future. Infants who received ≥1 dose of palivizumab during the 2006-2010 respiratory syncytial virus (RSV) seasons at 29 sites were ...
Zhang Bo B Section on Developmental Affective Neuroscience, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, - - 2012
The development of separation response behaviors in infant rhesus macaques across the first 6 months of life was assessed. Seventeen infants underwent a neonatal assessment at 7, 14, 21, and 30 days of age which included a brief period of social isolation. At 3 and 6 months of age these ...
Miller E Kathryn - - 2012
To assess incidence, burden of illness, and risk factors for human rhinoviruses (HRVs) in a cohort of very low birth weight (VLBW) infants. A 2-year prospective cohort study was conducted among VLBW premature infants in Buenos Aires, Argentina. Infants were enrolled in the NICU from June 1, 2003, to May ...
Yadav Sucheta - - 2011
OBJECTIVE: To compare the efficacy of bubble and conventional nasal continuous positive airway pressure (CPAP) in preventing extubation failure (EF) in preterm infants. METHODS: Infants of gestation ≤32 wk and birth weight <1500 g, ready for initial extubation within first wk of life were randomly allocated to either bubble (n = 16) or conventional ...
Eckert G U - - 2012
This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP. A prospective cohort of preterm ...
Kato Toru - - 2011
We report a preterm infant, who showed abnormal amplitude-integrated electroencephalogram (aEEG) findings 1h after birth and later developed cystic periventricular leukomalacia (PVL). The patient was a girl with a gestational age of 29weeks. She was delivered by emergency cesarean section because of placental abruption and intrauterine co-twin demise. Artificial ventilation ...
Ohman Anna - - 2011
Infants with congenital muscular torticollis (CMT) are at risk of developing skull asymmetry. The aim of this study was to investigate the inter-rater and intra-rater reliability of a modified "severity scale for assessment of plagiocephaly" among physical therapists (PT). Thirty-nine members of a network of PTs working with infants with ...
Saeedeh Tarvij Eslami - - 2011
Background/Objective:  To evaluate the characteristics and accuracy of cerebrospinal fluid (CSF) values of neonatal meningitis, we compared CSF values in newborns and infants until 2 months old with or without meningitis. Methods.  This case-control study was performed on 120 newborns and infants until 2 months old. 60 patients with meningitis ...
Savino A - - 2011
Purpose: Thyroidal hormones are important for bone development, and ultrasonographic (US) evaluation of the distal femoral epiphysis (DFE) has recently been suggested as a new method for the assessment of skeletal maturity in infants. A delayed bone maturation, expressed by a smaller or absent DFE nucleus (in terms of DFE ...
Chowdhury Olie - - 2011
ObjectivesTo determine the impact of different volume-targeted (VT) levels during volume-targeted ventilation (VTV) on the work of breathing (WOB) of infants born at or near term and to investigate whether a level of VT reduced the WOB below that experienced on respiratory support without VT.DesignProspective crossover study.PatientsSixteen infants, median gestational ...
van Pul C - - 2011
BACKGROUND AND PURPOSE:Signal-intensity abnormalities in the PLIC and thinning of the CC are often seen in preterm infants and associated with poor outcome. DTI is able to detect subtle abnormalities. We used FT to select bundles of interest (CC and PLIC) to acquire additional information on the WMI.MATERIALS AND METHODS:One ...
Igwegbe Anthony O - - 2011
OBJECTIVE: To evaluate the impact of the introduction of the Service Compact with all Nigerians (SERVICOM) contract on maternal health at Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria. METHODS: A retrospective and comparative study of maternal deaths between 2004 and 2010 was carried out. The main outcome measures were yearly ...
Coovadia Hoosen M - - 2012
Nevirapine given once-daily for the first 6, 14, or 28 weeks of life to infants exposed to HIV-1 via breastfeeding reduces transmission through this route compared with single-dose nevirapine at birth or neonatally. We aimed to assess incremental safety and efficacy of extension of such prophylaxis to 6 months. In ...
Imwong Mallika M Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, - - 2012
In a prospective infant cohort, 21 infants developed Plasmodium vivax malaria during their first year. Twelve of their mothers also had vivax malaria in the corresponding pregnancies or postpartum period. The genotypes of the maternal and infant infections were all different. Eight of the 12 mothers and 9 of the ...
Yin Jie - - 2011
Human breast milk samples collected from mothers (n=110) who lived in Chengdu, Sichuan Province, southwestern China in 2009 were analyzed to determine the concentrations of 13 musk compounds. Possible relationships between musk concentrations and some personal characteristics were also studied. Only five target analytes were detected in the milk samples ...
O'Shea Joyce E - - 2012
Introduction:To better understand whether preeclampsia (PE) increases the risk of bronchopulmonary dysplasia (BPD).Results:Of 753 infants alive at 36 wks, 138 (18.3%) were exposed to PE. BPD was not significantly related to exposure to PE either before (odds ratio (OR) 0.73; 95% confidence interval (CI) 0.50, 1.06) or after adjustment for ...
Payne Matthew S - - 2012
Multiplex, real-time PCR for the identification of Ureaplasma urealyticum and Ureaplasma parvum was performed on nucleic acids extracted from sequential endotracheal aspirates obtained from preterm neonates born at <29 weeks of gestation and ventilated for more than 48 h admitted to two level 3 neonatal intensive care units. Specimens were ...
Darmstadt Gary L - - 2011
We sought to determine the effects of maternal zinc supplementation on skin infections among infants in poor urban areas of Dhaka, Bangladesh. A double-blind, placebo-controlled, randomized trial was conducted among 199 and 221 Bangladeshi infants whose mothers were administered 30 mg daily of zinc or placebo, respectively. The mothers were ...
Shimi M Sami El - - 2011
Abstract Objective: Intraventricular haemorrhage (IVH) is a major problem in premature infants. Our objective is to assess the early predictive value of vascular endothelial growth factor (VEGF) for development of IVH and management of its squeal in preterm neonates. Methods:We prospectively studied 150 preterm neonates (PT) less than 34 weeks ...
Johnson Leigh F - - 2011
BACKGROUND:: Guidelines for treatment of pediatric HIV have recently changed to recommend that all infants who are identified as HIV-infected should start antiretroviral treatment (ART) immediately, regardless of their immunologic or clinical status. This study aims to assess the likely impact of this change in guideline in South Africa. METHODS:: ...
Doheny Laura - - 2011
Abstract Objective. Preterm infants experience frequent cardiorespiratory events (CREs) including multiple episodes of apnea and bradycardia per day. This physiological instability is due to their immature autonomic nervous system and limited capacity for self-regulation. This study examined whether systematic exposure to maternal sounds can reduce the frequency of CREs in ...
Hespos Susan J - - 2011
Infants can track small groups of solid objects, and infants can respond when these quantities change. But earlier work is equivocal about whether infants can track continuous substances, such as piles of sand. Experiment 1 (N = 88) used a habituation paradigm to show infants can register changes in the size of ...
Samad L - - 2011
BACKGROUND: Intussusception is the most common cause of acute intestinal obstruction in infants. This study examined the clinical presentation, management and outcomes of intussusception in this age group. METHODS: Prospective surveillance of intussusception in infants was carried out between March 2008 and March 2009 in the UK and Ireland. Monthly ...
Nordhov S Marianne - - 2011
OBJECTIVES:The aim of this study was to examine the effectiveness of an early intervention program on behavioral outcomes at corrected age of 5 years for children with birth weights (BWs) of <2000 g.METHODS:A randomized controlled trial of a modified version of the Mother-Infant Transaction Program was performed. Outcomes were measured ...
Saraswat A - - 2011
Aim:  To identify the optimal sensor application method which gave the quickest display of accurate heart rate (HR) data using the Nellcor OxiMax N-600x pulse oximeter (PO). Methods:  Stable infants who were monitored with an electrocardiograph were included. Three sensor application techniques were studied: (1) sensor connected to cable, then ...
Chappé Céline - - 2011
Human Astrovirus (HAstV) is a causative agent in pediatric viral epidemic gastroenteritis but its role in neonatal pathology is not established. Aim:  To describe clinical signs associated with HAstV in stools in neonatal units. Methods:  During 2005-2006 all stool virology performed for isolated digestive symptoms or suspicion of neonatal infection ...
Manzoni Paolo - - 2011
BACKGROUND:Lactoferrin is a mammalian milk glycoprotein involved in innate immunity. Recent data show that bovine lactoferrin (bLF) prevents late-onset sepsis in preterm very low birth weight (VLBW) neonates.METHODS:This is a secondary analysis of data from a multicenter randomized controlled trial where preterm VLBW neonates randomly received bLF (100 mg/day; group ...
Wainer Stephen - - 2011
OBJECTIVES:Our goal was to assess the impact of programmatic and coordinated use of transcutaneous bilirubinometry (TcB) on the incidence of severe neonatal hyperbilirubinemia and measures of laboratory, hospital, and nursing resource utilization.METHODS:We compared the neonatal hyperbilirubinemia-related outcomes of 14 796 prospectively enrolled healthy infants ≥35 weeks gestation offered routine TcB ...
Séguéla Pierre-Emmanuel - - 2012
The association between long QT interval and sudden infant death syndrome has been clearly established. Several studies have been conducted to determine the evolution of the QT interval in childhood from birth, but only in full-term newborns. However, data on the QT interval in pre-term infants are extremely scarce. The ...
Engmann Cyril - - 2011
Objective  To calculate perinatal mortality (stillbirth and early neonatal death: END) rates in the Upper East region of Ghana and characterize community-based stillbirths and END in terms of timing, cause of death, and maternal and infant risk factors. Methods  Birth outcomes were obtained from the Navrongo Health and Demographic Surveillance ...
Xu Xijin - - 2011
To assess the impact of exposure to informal e-waste recycling on birth outcomes. We compared record-based birth outcomes (n=24,493) and levels of cord blood lead (CBPb) (n=531) in Guiyu and a control area in Xiamen. Guiyu births showed significantly higher rates of adverse birth outcomes including stillbirth (4.72% vs. 1.03%), ...
Dorum Sevil - - 2011
OBJECTIVE: To determine the level and distribution of Cystatin C values in full-term and preterm healthy neonates for the purpose of diagnosis and follow-up of renal diseases of the neonates. METHODS: Eighty-eight newborn infants, including 55 preterm and 33 term born in the authors' hospital having no urinary tract pathology, ...
Bettelheim K A - - 2011
Several studies have indicated a possible causative role of toxigenic bacteria in sudden infant death syndrome (SIDS). This study examined the effect of toxigenic E. coli on pregnant and infant mice to determine if these animals could be used as a model for SIDS pathogenesis. Strains of E. coli from ...
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