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Chay O M - - 1990
We present 4 neonates with enteroviral meningitis. The cerebrospinal fluid findings were variable and posed a diagnostic problem. Immediate outcome was excellent and 3 of the 4 infants were normal at follow-up at 6 months of age. However long-term follow-up will be necessary to to determine any long-term sequelae.
Lisby-Sutch S M - - 1990
The epidemiology, pathogenesis, diagnosis, complications and sequelae, and therapy of otitis media are reviewed. Otitis media is one of the most common infections in infants and children. Epidemiologic studies have identified season of the year, bottle versus breast feeding, socioeconomic status, race, sex, and daycare attendance as factors associated with ...
Fujihara S - - 1989
Polyamines in various root nodule bacteria including Bradyrhizobium japonicum, Rhizobium fredii, R. leguminosarum, R. meliloti and R. loti were identified by capillary gas chromatography. Homospermidine was the polyamine present in highest concentration in all the rhizobia tested. In addition to putrescine and homospermidine, fast-growing type of rhizobial cells contained a ...
Coovadia Y M - - 1989
All cases of bacterial meningitis in the neonatal unit at King Edward VIII Hospital, Durban for the period 1 January 1981 to 31 December 1987 were reviewed. In particular, we looked at the impact of cefotaxime on mortality rates and amikacin on the incidence of hospital-acquired Gram-negative bacillary (GNB) meningitis. ...
Manjra A I AI Department of Paediatrics, University of Natal, - - 1989
Meningitis and ventriculitis in a 6-day-old neonate caused by a Gram-negative glucose-non-fermenting organism, Achromobacter xylosoxidans, was resistant to most antibiotics except ceftazidime and imipenem. The organism became resistant after 28 days treatment with ceftazidime. When the infant was 7 weeks old, imipenem became available but, in spite of 3 days ...
Lenoir P - - 1989
Candida albicans meningitis was found in an otherwise healthy 44-day-old premature infant whose birth weight was 1,860 gm. Almost no abnormal clinical or neurologic findings were present. The electroencephalogram, however, was abnormal. All previous body fluid cultures were negative. The combined use of amphotericin B and 5-fluorocytosine resulted in negative ...
Mustafa M M - - 1989
Intraventricular gentamicin therapy in infants with gram-negative enteric bacillary meningitis and ventriculitis is associated with increased mortality. Therefore, endotoxin, interleukin-1 beta, and cachectin (tumor necrosis factor) concentrations in ventricular cerebrospinal fluid from 21 infants (11 received intravenous antibiotics alone and 10 received intraventricular gentamicin also) were determined and correlated with ...
Bakheit A M - - 1989
A 69 year old female presented with eight discrete episodes of paraparesis over a period of six weeks. Each episode lasted between 10 and 30 minutes and resolved spontaneously. The cause of her symptoms was not established during life and at necropsy she was found to have granulomatous meningitis of ...
Platt M S - - 1989
We show that postmortem cerebrospinal fluid (CSF) pleocytosis is a common event. Postmortem cerebrospinal or ventricular fluid was obtained from children and adults. The cells were counted and morphologically characterized using several histochemical markers. Infants exhibit a brisk postmortem CSF pleocytosis. Sudden infant death cases have relatively high CSF counts. ...
Jacobs R F - - 1989
Pharmacokinetic studies on cefotaxime/desacetylcefotaxime were carried out in very low birth weight newborns (n = 18; 500-1500 g; 28.4 +/- 2.4 weeks gestational age) during the first week of life. We have previously reported that the elimination t 1/2 of cefotaxime (3.4-6.4 h) and desacetylcefotaxime (9.4 h) was longer than ...
Bonadio W A - - 1989
A retrospective study of 72 infants under four weeks of age with meningitis evaluated over almost four years was performed to determine the predictive value of the CBC differential ratio (% lymphocytes + % monocytes/% polymorphonuclear leukocytes + % band forms) profile in distinguishing those with bacterial from those with ...
Baker R C - - 1989
A prospective study of the effects of fever reduction on the clinical appearance of infants at risk for occult bacteremia was undertaken to study the hypothesis that infants with bacteremic illness fail to improve clinically following defervescence compared with infants with benign viral illness. A total of 154 children were ...
Gruskay J - - 1989
We identified 10 infants (mean +/- SD birth weight, 1000 +/- 500 g; gestation, 29 +/- 3 weeks; postnatal age, 24 +/- 19 days) who had Staphylococcus epidermidis meningitis despite unremarkable cerebrospinal fluid (CSF) blood cell counts and glucose and protein levels. Staphylococcus epidermidis meningitis was diagnosed if all the ...
Kaplan S L - - 1989
Bacterial interstrain variation for cochlear invasion was studied by intraperitoneal inoculation of infant rats with Haemophilus influenzae type b. Eight pairs of CSF isolates from children with or without deafness due to meningitis were injected into half of each litter in separate experiments. At 48 h, quantitative CSF culture results ...
Mirro R - - 1989
Lumbar CSF eicosanoids were measured in 11 neonates with perinatal asphyxia and 12 neonates with suspected sepsis. In the asphyxia group low levels of thromboxane B2 and prostaglandin F2a were detected in five neonates, all of which had had a lumbar puncture prior to 4 hours of age. In the ...
Riddell M G - - 1989
Fifty-three zona pellucida-intact ova were collected surgically from superovulated, Brucella -free mixed-breed ewes. Groups containing two to seven ova were incubated in medium containing Brucella abortus . All groups of ova were then washed 10 times, and ova and sequential washes were cultured for the isolation of B. abortus . ...
McCracken G H GH - - 1989
Concentrations of interleukin 1-beta and tumor necrosis factor in cerebrospinal fluid (CSF) of 42 neonates with Gram-negative enteric bacillary meningitis were determined and correlated with outcome and other CSF indices. At the time of diagnosis interleukin 1-beta was detected in CSF of 40 infants and peak concentrations correlated significantly with ...
Bennet R - - 1989
The outcome of neonatal septicemia in 320 infants seen during 1969-83 has been evaluated. Mortality decreased from 27% to 12%. The incidence of moderate to severe handicaps in survivors remained unchanged at around 20%. Sixty percent of these handicapped children had meningitis or osteomyelitis, and many of these were healthy ...
Ryczko B - - 1988
Spontaneous (congenital) cerebrospinal fluid (CSF) otorrhea is a rare occurrence with less than 100 cases being reported in the literature. In infants and children, it may present as otitis media with effusion. A 4-month-old infant, who was diagnosed with severe to profound sensorineural hearing impairment and spontaneous CSF otorrhea, initially ...
Kaplan S L - - 1988
The mechanism(s) by which the lipopolysaccharide (LPS) of Haemophilus influenzae type b may contribute to the virulence of this organism is unclear. Purified LPS of Haemophilus influenzae type b or phosphate buffered saline was administered intranasally to infant rats prior to the intranasal instillation of approximately 2-20 x 10(6) cfu ...
Mueller R A - - 1988
1. Examination of the cerebrospinal fluid (CSF) of head-injured patients reveals that the concentration of intraventricular xanthine is elevated and that of uridine is decreased relative to those of adult lumbar CSF. 2. No correlations were observed between CSF lactate and CSF hypoxanthine, xanthine, or uridine, suggesting that changes in ...
Shohat M - - 1988
We studied 25 infants aged less than 9 months who were diagnosed as having nonpolio enteroviral meningitis (EM) confirmed by virus isolation from cerebrospinal fluid (CSF). CSF protein, glucose and cellular content in these infants was compared with that of 125 age-matched febrile infants without cerebromeningeal illness. In order to ...
Greiner J - - 1988
To verify the reliability of secretor status for prenatal diagnosis of myotonic dystrophy (DM), 179 amniotic fluid samples were compared with saliva or urine samples of the infants by hemagglutination inhibition. While no discrepancies were observed, problems could arise with intermediate results. Additionally, secretor typing is only informative in 8.4% ...
Mochizuki H - - 1988
In vitro and in vivo antibacterial activities and pharmacokinetics of M14659 were investigated. In vitro activity of M14659 was superior to that of ceftazidime against Staphylococcus aureus. Against Gram-negative bacteria except Pseudomonas aeruginosa, its activity was almost equal to that of ceftazidime. M14659 was more active against P. aeruginosa including ...
Jacobs R F - - 1988
18 infants and children (1 week to 3 months of age) were treated with cefotaxime 200 mg/kg/day for Gram-negative enteric bacillary meningitis. 17 of these patients (94.4%) survived, with a complication rate of 23.5% (4/17 patients). The follow-up cerebrospinal fluid cultures at 24 hours were sterile in all patients. Cefotaxime ...
Karma P H - - 1987
The middle ear fluid (MEF) bacteriology of 107 attacks of acute otitis media (AOM) in 101 infants less than 3 months old was analyzed. A total of 108 bacteria were isolated from 85 attacks. Major AOM-pathogens, S. pneumoniae (19%), H. influenzae (9%) or B. catarrhalis (7%) were cultured in approximately ...
Arimoto S - - 1987
We have shown in our earlier reports (Arimoto et al., 1980a, b) that hemin and some other porphyrins can inhibit the mutagenicity in Salmonella of heterocyclic amines derived from cooking of proteins. A direct interaction between hemin and the mutagens was implicated on the basis of the observation that some ...
King J C JC - - 1987
We evaluated fever in 342 hospitalized infants less than 8 weeks of age. Sixteen infants (5%) had bacteremia or bacterial meningitis. Fifty-two percent of the infants were admitted during the months of July through September. We found no significant relationship between season, sex, height of fever, or erythrocyte sedimentation rate ...
Harrison C J - - 1987
The epidemiology, microbiology and clinical outcome of the conjunctivitis-otitis syndrome (CJ-AOM) was investigated in a rural private practice concurrent to a double blind placebo-controlled study of orally administered amoxicillin for prevention of acute otitis media (AOM) secondary to conjunctivitis. Bacterial pathogens were isolated when greater than 15 polymorphonuclear leukocytes/high power ...
Schlesinger L S - - 1987
In an effort to ascertain important epidemiologic and prognostic risk factors, we analyzed 33 cases of Staphylococcus aureus meningitis occurring over an 8-year period (1976 to 1984). Staphylococcus aureus caused 6% of all bacterial meningitis at our University Hospital. Fifty percent of cases were pediatric and included 7 newborn infants, ...
Bennhagen R - - 1987
A nationwide retrospective epidemiological survey of neonatal meningitis in Sweden was performed in order to estimate possible changes in incidence, etiology and mortality. The total number of newborns with meningitis was 137 and 40 (29%) were preterm (less than 37 gestational weeks) infants and 27 of these preterm boys (20%). ...
Lin F C - - 1987
Between February and June, 1983, four cases of Citrobacter diversus neonatal meningitis were identified at a suburban Baltimore hospital. One of the 4 infants died at age 13 months, 2 (both of whom had brain abscesses) have evidence of developmental delay and 1 appears to be normal after 33 months ...
Hall J E - - 1987
Amphotericin B (Amp-B) serum concentrations were determined in five infants with disseminated candidiasis. All patients had positive blood cultures for Candida and one patient had Candida albicans meningitis. Amp-B sterilized the blood and the cerebrospinal fluid within four to nine days. Total doses of Amp-B varied from 11.6-62.3 mg. There ...
Mushinsky R F - - 1986
Compatibility studies were conducted of sulbactam/ampicillin in infusion diluents that are reported to be compatible with ampicillin sodium. A high-performance liquid chromatographic system that simultaneously detects sulbactam and ampicillin was used to determine whether the infusion diluents and the conditions of use recommended for ampicillin sodium are applicable to sulbactam/ampicillin. ...
Loughran C F - - 1986
A comparative trial of ioxaglate sodium meglumine and iopamidol in excretory urography was undertaken. The study failed to demonstrate any statistically significant differences between the two media in terms of urographic quality. Diagnostically adequate urograms were obtained in 92.6% of patients receiving ioxaglate and 89.6% of patients receiving iopamidol. There ...
Ment L R - - 1986
Despite significant improvement in mortality rate, survivors of neonatal bacterial meningitis experience a significant incidence of neurodevelopmental sequelae. Neuropathologic studies have demonstrated vasculitis, arachnoiditis, and ventriculitis with secondary edema and encephalomalacia. Areas of cerebral infarction, most commonly thought to be venous in origin, have been reported as well. We performed ...
Javaheri S - - 1986
We hypothesized that, during isosmotic isonatremic HCl acidosis with maintained isocapnia in cisternal cerebrospinal fluid (CSF), acetazolamide, by inhibiting carbonic anhydrase (CA) in the central nervous system (CNS), should produce an isonatric hyperchloric metabolic acidosis in CSF. Blood and CSF ions and acid-base variables were measured in two groups of ...
Goossens H - - 1986
In a nosocomial outbreak of Campylobacter jejuni infection 11 newborn infants (7 female, 4 male) had meningitis. The outbreak was caused by a single strain of C jejuni, as demonstrated by biotyping (biotype I), serotyping (LAU 7/PEN 18 on heat-stable antigens, a new serotype on heat-labile antigens), and the identical ...
Notterman D A - - 1986
In an 8-month-old infant with tuberculous meningitis treatment with isoniazid was unsuccessful and was associated with lower than expected plasma concentrations of isoniazid (measured concentration 0.1 microgram/mL). The infant had received isoniazid as a crushed tablet admixed with apple sauce. Oral administration of the parenteral solution of isoniazid (Nydrazid, Squibb) ...
Rennie J M - - 1986
6-Ketoprostaglandin F1 alpha determinations were made by radioimmunoassay on samples of cerebrospinal fluid from 41 neonates. Levels were below the smallest quantity detectable (50 pg/ml) in 29 and greater than 200 pg/ml in only 3 babies. These results suggest that 6-ketoprostaglandin F1 alpha is not a major prostaglandin in the ...
Kuramoto S - - 1986
Non-invasive measurement of the intracranial pressure (ICP) via the anterior fontanelle by using an applanation transducer has been performed. Recently, a new fontanometer using an applanation transducer has been developed in our department by improving the conventional Statham transducer, P-50 which is currently accepted for its high reliability. In this ...
Wynder S G - - 1986
Uvulitis and Hemophilus influenzae b (HIb) bacteremia occurred in two infants. Uvulitis may be associated with HIb bacteremia, with or without epiglottitis. An acutely inflamed uvula in a febrile infant should alert the physician to the possibility of HIb bacteremia and potentially serious sequelae. Hospitalization and parenteral antibiotic therapy are ...
Beckwith D G - - 1986
A 4-week-old female was hospitalized because of vomiting, irritability, and nuchal rigidity. A spinal fluid culture yielded Corynebacterium aquaticum. The diagnosis of C. aquaticum meningitis in this infant was supported by the following cerebrospinal fluid findings: Gram stain, elevated protein, hypoglycorrhachia, positive C-reactive protein, and polymorphonuclear leukocytosis. Antigen studies for ...
Costarino A - - 1986
In this article, the authors introduce the concept of a transitional physiology which governs fluid and electrolyte balance in the immediate postnatal period. The important impact of the extrauterine environment on fluid balance is also discussed. Finally, the pathophysiology of diuresis in RDS, and fluid shifts in the VLBW infant ...
Goodwin M A - - 1985
Brilliant pigment powder was used to measure minimum gastrointestinal transit times (GTT) in control and cloned-reovirus-inoculated turkey poults. Compared with controls, inoculated poults had longer GTT at 120 hr (P less than 0.05) but not at 24 and 72 hr after receiving a single oral dose of cloned reovirus. Reovirus ...
Tauxe R V - - 1985
After the Puerto Rico Department of Health received a report of salmonellosis in an infant who had contact with a pet turtle, we conducted a case-control study in two urban areas in Puerto Rico to measure the extent of pet turtle-associated salmonellosis there. Ten (17%) of 60 infants with salmonellosis ...
Rahbar F - - 1985
A two-day-old black male term infant developed meningitis due to Hemophilus para-influenzae, a rare cause of neonatal meningitis. The organism was sensitive to ampicillin and chloramphenicol. Of interest was that the mother had the same organism in her cervix. The need for prompt investigation and institution of appropriate antibiotic therapy ...
Omene J A - - 1985
In a prospective study of high-risk newborn infants, the specificity and sensitivity of CSF/blood glucose ratio were studied in 35 newborn infants with meningitis and 100 high-risk neonates without meningitis. High CSF/blood glucose ratios of 0.93 (0.17) (Mean (S.D.) ) for preterm infants and 0.96 (0.30) (Mean (S.D.) ) for ...
Meade R H RH - - 1985
Meningitis occurs more often in the neonatal period than at any other time of life. It is often the result of maternal infection and occurs more often in the prematurely born infant and in those born after prolonged rupture of the membranes. Even with early treatment, the chance for survival ...
Massaro A R - - 1985
It has previously been demonstrated that both Myelin Basic Protein (MBP) and S-100 are released in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients during acute phases of exacerbation of the disease. In order to investigate the pathobiological significance of the release of these two proteins into the CSF, ...
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