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Dargaville Peter A - - 2014
It is now recognized that preterm infants <=28 weeks gestation can be effectively supported from the outset with nasal continuous positive airway pressure. However, this form of respiratory therapy may fail to adequately support those infants with significant surfactant deficiency, with the result that intubation and delayed surfactant therapy are ...
Snyder Christopher W CW Division of Pediatric Surgery, All Children's Hospital, John Hopkins University School of Medicine, St. Petersburg, FL, USA, - - 2014
Existing minimal-access surgical approaches for correction of symptomatic diaphragmatic eventration may be technically difficult in neonates and infants. We report technical details and initial outcomes of a novel, simple thoracoscopic repair technique. The technique uses one 3-mm camera port, a 3-mm instrument incision without a port, and an 18-gauge spinal ...
Oh Albert K - - 2014
Objective :  To analyze the hospital course of 100 consecutive infants after primary cleft lip repair (PCLR) and identify factors related to length of stay (LOS). Design :  Retrospective analysis of 100 consecutive infants who were routinely admitted after PCLR. Setting :  Tertiary care center. Patients :  One hundred consecutive ...
Moldenhauer Julie S JS Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, Pa., - - 2014
Background: Fetal myelomeningocele (fMMC) repair has become accepted as a standard of care option in selected circumstances. We reviewed our outcomes for fMMC repair from referral and evaluation through surgery, delivery and neonatal discharge. Material and Methods: All patients referred for potential fMMC repair were reviewed from January 1, 2011 ...
Skram Marius M Department of Pediatrics, Nordland Hospital, Bodø, Norway Department of Pediatrics, St. Olavs University Hospital, Trondheim, Norway Department of Medical Microbiology, St. Olavs University Hospital, Trondheim, Norway Department of Pediatrics, Ålesund Hospital, Ålesund, Norway Norwegian University of Science and Technology, Trondheim, - - 2014
Human parechovirus genotype 3 (HPeV-3) has been linked to meningoencephalitis and sepsis-like disease in infants younger than 3 months. We present clinical and phylogenetic characteristics of 15 infants who were admitted with HPeV-3 infections to 3 hospitals in Norway during a period of 7 months in 2011. Eleven patients had ...
Adanur Senol S Department of Urology, School of Medicine, Ataturk University, 25240, Erzurum, Turkey, - - 2014
We present the efficacy of shockwave lithotripsy (SWL) therapy administered with sedoanalgesia in infants with kidney stones. We enrolled 102 patients aged 5-24 months who had kidney stones and received SWL therapy under sedoanalgesia using a Siemens Lithostar Modularis device. Patient and stone characteristics, therapy parameters, pain score, complications, discharge time, ...
Arenas-Lopez S S Department of Pharmacy, Evelina London Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, King's Health Partners, Westminster Bridge Road, London SE1 7EH, - - 2014
Clonidine is a useful analgesic-sedative agent; however, few data exist regarding its use in infants after congenital heart disease surgery. We thus aimed to assess the absorption and safety of enterally administered clonidine in this setting. Sixteen infants (median age 6.7 months) received a single nasogastric dose of 3 μg ...
Riera Joan J Department of Neonatology, La Paz University Hospital, Madrid, Spain; Center for Biomedical Technology, Technical University, Madrid, Spain. Electronic address: - - 2014
To describe an alternative analysis in the frequency-domain of the temporal relationship between 2 biological signals and evaluate the method's predictive capacity for classifying infants at risk for an adverse outcome. We studied 54 infants (mean gestational age 27 weeks) with invasive mean arterial blood pressure monitoring. The bivariate autoregressive spectral ...
Wiland Emily L EL *Division of Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH †Division of Pediatric Radiology, Cincinnati Children's Hospital Medical Center ‡Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, - - 2014
We report our institution's 5-year experience with upper gastrointestinal study with small bowel follow through (UGI-SBFT) and contrast enema (CE) for the diagnosis of post-necrotizing enterocolitis (NEC) stricture. We hypothesized that sensitivity and specificity of UGI-SBFT and CE were < 85% in diagnosing post-NEC stricture. A retrospective observational cohort study was performed. ...
Kulkarni Abhaya V AV Hospital for Sick Children, University of Toronto, Ontario, - - 2014
Object The use of endoscopic third ventriculostomy (ETV) with choroid plexus cauterization (CPC) has been advocated as an alternative to CSF shunting in infants with hydrocephalus. There are limited reports of this procedure in the North American population, however. The authors provide a retrospective review of the experience with combined ...
Ferdman Dina J DJ Division of Pediatric Cardiology, Department of Pediatrics, Columbia University Medical Center, College of Physicians and Surgeons, New York, New - - 2014
Pulmonary arterial hypertension (PAH) associated with chronic lung disease of infancy can be a life-threatening disease affecting an increasing number of former premature infants. There is a need for improved delivery of targeted PAH therapies for this subgroup of patients who have severe and persistent PAH despite standard respiratory care ...
Serna-Tamayo Cristian - - 2014
Acne may present in neonates, infants, and small children. Neonatal and infantile acne vulgaris are not considered to be rare. The presentation of acne in this patient population sometimes represents virilization and may portend later development of severe adolescent acne. Neonatal and infantile acne vulgaris must be distinguished from other ...
Msukwa Gerald G Department of Ophthalmology, University of Malawi College of Medicine, Lilongwe, - - 2014
Neonatal conjunctivitis is associated with poor prenatal care worldwide. Data on neonatal conjunctivitis is scarce in Malawi. This study describes risk factors associated with conjunctivitis in neonates born in a large tertiary care hospital in Blantyre, Malawi. Medical records of a retrospective cohort of 231 neonates diagnosed with conjunctivitis from ...
Luchsinger Vivian V Program of Virology of the Institute of Science in Biomedicine, Faculty of Medicine, University of Chile, Santiago, - - 2014
Respiratory syncytial virus (RSV) and rhinovirus (HRV) are the main cause of acute lower respiratory tract infections (ALRTIs) in infants. Viral and host-related risk factors for severe disease have also not been clearly established. To assess whether certain viral features of RSV and, or HRV are associated with severe ALRTI. ...
Kracer Bernardo B Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford, Palo Alto, CA. Electronic address: - - 2014
To characterize the implementation of hypothermia for neonatal hypoxic ischemic encephalopathy (HIE) in a population-based cohort. Using the California Perinatal Quality Care Collaborative and California Perinatal Transport System linked 2010-2012 datasets, we categorized infants ≥36 weeks' gestation with HIE as receiving hypothermia or normothermia. Sociodemographic and clinical factors were compared, and ...
Corey Kristin M KM Duke Clinical Research Institute, Durham, NC, - - 2014
Gastroschisis and omphalocele are the most common anterior abdominal wall defects affecting infants. There are few large cohort studies describing the frequency of associated anomalies in infants with these 2 conditions. We describe associated anomalies and outcomes in infants with these defects using a large, multi-center clinical database. We identified ...
Mery Carlos M CM Division of Congenital Heart Surgery, Texas Children's Hospital, and Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas. Electronic address: - - 2014
The optimal treatment for infants with aortic coarctation and hypoplastic aortic arch is controversial. The goal of this study was to report the short-term and mid-term outcomes of aortic arch advancement (AAA) in infants with hypoplastic aortic arch. All infants who underwent AAA at our institution from 1995 to 2012 ...
Wang Lai Shuan LS Departments of Neonatology and *Gynecology, Fudan University, Shanghai , China. Correspondence to: Wenhao Zhou, Department of Neonatology, Childrens Hospital of Fudan University, 399 Wanyuan Road, Shanghai, China. - - 2014
To investigate the clinical course and mid-term prognosis of neonates admitted with pleural effusion. Case records of 38 neonates admitted with pleural effusion were retrieved and analyzed. 16 (42%) patients had congenital and 22 (58%) patients had acquired causes of pleural effusion. The most common causes of congenital pleural effusion ...
Shumer Daniel E DE Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, - - 2014
Subcutaneous fat necrosis (SCFN) is a rare form of panniculitis in infants that generally occurs following birth trauma, meconium aspiration, or therapeutic cooling. Severe hypercalcaemia occurs in a subset of patients, but data on its presentation, management and outcomes are limited. This report details the clinical course and complications of ...
Manzoni Paolo P 1Neonatology and NICU, S. Anna Hospital, Turin, Italy; 2Astellas Pharma Global Development, Northbrook, IL, United States America; 3Astellas Pharma Europe Ltd, Chertsey, United Kingdom; 4Infectious Diseases Unit, 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Science, Hippokration Hospital, Thessaloniki, - - 2014
Invasive fungal infections cause excessive morbidity and mortality in premature neonates and severely ill infants. Safety and efficacy outcomes of micafungin were compared between prematurely and non-prematurely born infants<2-year-old. Data were obtained from all completed phase I-III clinical trials with micafungin that had enrolled infants (<2-year-old) that were listed in ...
Kanburoglu Mehmet K MK Servicio de Pediatría, Fatih University Medical - - 2014
Conventional intubation for pulmonary management in children with a difficult airway may be very challenging even in skilled hands. Rapid advancements in respiratory care have reduced the incidence of difficult tracheal intubation and the incidence of complications have decreased accordingly. However, serious unexpected complications still occur in some patients today. ...
Lasheen Abeer E AE Department of Pediatrics, Security Forces Hospital, Riyadh, Kingdom of Saudi - - 2014
To determine the outcome of infants born to diabetic mothers at Security Forces Hospital, Riyadh, Saudi Arabia, and compare the complications seen in these infants with infants of non-diabetic mothers. This is a concurrent prospective cohort study of a population of newborn infants delivered at Security Forces Hospital, Riyadh, Saudi ...
Köse Doğan D Department of Pediatric Oncology, Selcuk University Faculty of Medicine, Konya, - - 2014
Synovial sarcoma is rarely detected in infants, with an annual incidence of 0.5 per million. Synovial sarcoma occurs more frequently in adolescents and young adults, with the majority of patients presenting between 15 and 40 years of age. It is extremely rare, however, in pediatric patients under 2 years of ...
Zinna S S Nottingham University Hospitals NHS Trust, Nottingham, - - 2014
There is very little data available on the impact that respiratory viral infections (RVI) have on neonatal morbidity and mortality in the UK. Define the epidemiology and impact of RVIs in a UK NICU population. We conducted a retrospective case review of all NICU patients, at two large tertiary centres, ...
Lee Ji Eun JE Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, - - 2014
Dilated cardiomyopathy (DCMP) remains a life threatening disease in young patients and is often difficult to differentiate from myocarditis. Early recognition and treatment of DCMP are crucial for good prognoses in this patient population. The clinical course of patients with DCMP that result in cardiogenic shock varies according to the ...
Kose Mehmet M Department of Pediatrics, Division of Pediatric Pulmonology Unit, Erciyes University. - - 2014
Plasma gelsolin is a circulating actin-binding protein that has a protective role against tissue injuries. Our aim was to compare the baseline levels of gelsolin in premature infants with neonatal outcomes. A total of 32 preterm neonates born at 23-32 weeks of gestation were enrolled to the study. Plasma gelsolin ...
Kamrath Clemens C Division of Pediatric Endocrinology and Diabetology, Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany; Steroid Research and Mass Spectrometry Unit, Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany. Electronic address: - - 2014
Patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) have an impaired cortisol synthesis, but it is unknown whether the metabolism of glucocorticoids differs between neonates and infants with and without 21OHD. The objective of this study was to compare the glucocorticoid metabolism between neonates and infants with and ...
Wallenius Marianne M National Service for Pregnancy and Rheumatic Diseases, Dept. of Rheumatology, Trondheim University Hospital, Trondheim, Norway; Dept. of Neuroscience, Norwegian University of Science and Technology, Trondheim, - - 2014
Objective: To examine associations between systemic lupus erythematosus (SLE) and outcomes in first and subsequent births. Methods: Data from the Medical Birth Registry of Norway in the period 1.12.1998 to 31.12 2009 were used to assess maternal and perinatal outcomes in women diagnosed with SLE compared with the general population. ...
Cheng Henry H HH Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts. Electronic address: - - 2014
Cerebral blood flow velocity (CBFV) measured by transcranial Doppler sonography has provided information on cerebral perfusion in patients undergoing infant heart surgery, but no studies have reported a relationship to early postoperative and long-term neurodevelopmental outcomes. CBFV was measured in infants undergoing biventricular repair without aortic arch reconstruction as part ...
Ikeda Sayako S Department of Obstetrics and Gynecology, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, - - 2014
Abstract Objective: To clarify the association between amniotic neutrophil elastase levels and the development of bronchopulmonary dysplasia (BPD). Methods: The database between July 2001 and December 2012 was reviewed for women with amniocentesis on admission for amniotic fluid neutrophil elastase levels and with singleton deliveries between 22+0 and 31+6 weeks ...
Bennett Kelly A KA Department of Obstetrics and - - 2014
Object As more pediatric neurosurgeons become involved with fetal myelomeningocele closure efforts, examining refined techniques in the overall surgical approach that could maximize beneficial outcomes becomes critical. The authors compared outcomes for patients who had undergone a modified technique with those for patients who had undergone fetal repair as part ...
Cruz Ithier Mayra A MA Bayfront Health, St Petersburg, - - 2014
The objective of this study was to prove that the chronic use of indomethacin as a tocolytic agent does not affect neonatal outcomes. This is a retrospective cohort study of obstetrical patients from All Children's Perinatology Group diagnosed with preterm labor, cervical insufficiency, or both and exposed to prolonged indomethacin ...
Strand Eric A EA Washington University in St Louis, St Louis, - - 2014
The objective of this study was to examine maternal and neonatal outcomes for patients with previable and periviable preterm premature rupture of membranes (PPROM) who were expectantly managed. Retrospective cohort study of women with PPROM admitted to the hospital between January 1, 2007, and December 31, 2011. Pre- and periviable ...
Hilderman Courtney G E CG C.G.E. Hilderman, BScPT, Department of Physical Therapy, Faculty of Medicine, University of British Columbia, 212-2177 Wesbrook Mall, Vancouver, British Columbia, Canada V6T - - 2014
<LEAP> highlights the findings and application of Cochrane reviews and other evidence pertinent to the practice of physical therapy. The Cochrane Library is a respected source of reliable evidence related to health care. Cochrane systematic reviews explore the evidence for and against the effectiveness and appropriateness of interventions-medications, surgery, education, ...
Mohr Lynn D LD Lynn D. Mohr, MS, APN, PCNS-BC, CPN, Instructor, Rush University, Chicago, Illinois. Roxana Reyna, BSN, RN-NIC, WCC, Registered Nurse, Driscoll Children's Hospital, Corpus Christi, Texas. Rene Amaya, MD, FAAP, Specialist, Pediatric Infectious Disease, Houston, - - 2014
Treatment of the neonatal patient with clinically complex wounds creates a challenge due to the safety and efficacy issues associated with the use of many advanced wound care products. The purpose of this case series was to present outcomes of 3 neonates with wounds of differing etiologies managed by Active ...
Zahn Evan M EM The Divisions of Pediatric Cardiology and Neonatology, Department of Pediatrics and The Heart Institute, Cedars Sinai Medical - - 2014
Objectives: Describe a new technique for transcatheter patent ductus arteriosus (PDA) closure in extremely preterm infants using commercially available technology. Background: PDA in premature neonates continues to be a significant clinical problem contributing importantly to both morbidity and mortality. Surgical ligation and medical therapy both have their drawbacks. Material and ...
Cinel G G Pediatric Pulmonology Department, Faculty of Medicine, Hacettepe University, İhsan Doğramacı Children's Hospital, Ankara, - - 2014
Cytomegalovirus (CMV) pneumonitis in immunocompetent hosts is uncommon but is being recognized more frequently, particularly when presenting as severe viral pneumonia. The objective of this study was to examine lower respiratory tract CMV infection in immunocompetent wheezy infants, based on polymerase chain reaction (PCR) in bronchoalveolar lavage (BAL) fluid, to ...
Shitsama Sylvia S Division of Neurosurgery, Department of Surgery, Kijabe Hospital, Kijabe, - - 2014
Object Severe hydrocephalus and hydranencephaly are common congenital conditions in Kenya. In patients with these conditions, ventriculoperitoneal (VP) shunts are associated with appreciable complications and endoscopic third ventriculostomies (ETVs) have limited success. Endoscopic choroid plexus coagulation (CPC) to diminish CSF production is a potential treatment option. The purpose of this ...
Lobkova Nelya N Department of Orthopedics, Division of Podiatry, Mount Sinai Hospital, New York, New York (NL, - - 2014
The prevalence of breastfeeding among women in the United States is increasing along with the understanding of the importance of continually and exclusively breastfeeding an infant in the first half year of life. Modern necessities and problems evoke questions about what medications can be safely utilized by a breastfeeding mother ...
Khmour Ayman Y AY Department of Pediatrics, Kansas Mercy Children's - - 2014
Neonates with significant congenital diaphragmatic hernia (CDH) require cardiopulmonary support. Management has been characterized by progressive abandonment of hyperventilation. Ability to prognosticate outcomes using measures of ventilation and oxygenation with gentle ventilation remains unclear. We sought to determine whether assessment of gas exchange at the time of NICU admission is ...
McCuskee Sarah S 1Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom 2Division of Clinical Sciences, Northern Ontario School of Medicine, Sioux Lookout, ON, Canada 3Medical Records, Sioux Lookout Meno Ya Win Health Center, Sioux Lookout, ON, Canada 4Divison of Respirology, Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, - - 2014
High rates of lower respiratory tract infection (LRTI), including bronchiolitis and pneumonia, have been reported in Inuit infants living in arctic Canada. We examined rates of LRTI in First Nations Canadian infants living in the Sioux Lookout Zone, in northern Ontario. A retrospective review of hospital admissions for LRTI during ...
Garcia-Mata Serafin S Orthopedic Surgeon, Department of Orthopaedics, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain. Electronic address: - - 2014
Os vesalianum pedis is an accessory bone in the foot located proximal to the base of the fifth metatarsal within the peroneus brevis tendon, with a very low prevalence (0.1% to 1%), and is usually asymptomatic. Only 9 cases of symptomatic os vesalianum pedis have been reported. Other more common ...
Fischler Björn B Department of Pediatrics, CLINTEC, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. Electronic address: - - 2014
Neonatal cholestasis occurs in approximately 1 in 2500 term infants, the most common underlying disease being biliary atresia, viral infections and α1-antitrypsin deficiency. The incidence of cholestasis is much higher in extremely premature newborns. The etiology of biliary atresia remains unclear, which in turn makes the search for additional treatments ...
Pizarro Christian C Nemours Cardiac Center, Alfred I. duPont Hospital for Children, Wilmington, Delaware. Electronic address: - - 2014
Optimal perfusion strategies for neuroprotection during infant cardiac surgery remain undefined. Despite encouraging experimental data, neurodevelopmental (ND) outcomes after cardiac surgery in neonates and infants using deep hypothermic circulatory arrest (DHCA) with a period of intermittent perfusion have not been reported, and it is not known whether it can extend ...
Johnson Joyce T JT Division of Cardiology, Department of Pediatrics, University of Utah and Primary Children's Hospital, 100 N. Mario Capecchi Drive, Salt Lake City, UT, 84113, USA, - - 2014
Echocardiography provides adequate preoperative imaging for most young infants with congenital heart disease (CHD). When anatomic details require further clarification, cardiac magnetic resonance imaging (CMRI) may be useful but adds the risks of sedation or general anesthesia for a vulnerable population. This study aimed to determine the safety of CMRI ...
Vendettuoli V V NICU, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico-Università Degli Studi di Milano, Milan, - - 2014
The role of prone position in preterm infants has not been completely clarified. We investigated prone versus supine posture-related changes in respiratory system resistance (Rrs) and reactance (Xrs) measured by the Forced Oscillation Technique (FOT) in mechanically ventilated preterm newborns. Patients were studied in the supine versus prone positions in ...
Nelson Michelle A MA Duke University School of Nursing (Mss Nelson and Bradshaw) and Neonatal Nurse Practitioner Program, Duke University School of Nursing, Durham, North Carolina (Ms - - 2014
Few controlled trials exist to demonstrate the efficacy and the risks of pharmacologic agents used in treating pediatric, and more specifically neonatal patients. It is not different for the central nervous system altering class of drugs, benzodiazepines (BZDs). Little information is known about the long-term effects of BZDs use in ...
Bellamkonda-Athmaram V V Department of Pediatrics, Medical College of Wisconsin, Milwaukee, - - 2014
Alveolar capillary dysplasia is a rare and fatal disease of newborn infants. Here we describe a patient with alveolar capillary dysplasia, multiple congenital anomalies, a novel genetic mutation and previously undocumented airway findings on bronchoscopy. Knowledge of these associations may help diagnose this rare disorder in neonates with hypoxemic respiratory ...
Takeda Akiko A Department of Pediatrics, Okayama University Hospital, Okayama 700-8558, - - 2014
Acute megakaryocytic leukemia (AMKL) with t(1;22)(p13;q13) is a distinct category of myeloid leukemia by WHO classification and mainly reported in infants and young children. Accurate diagnosis of this type of AMKL can be difficult, because a subset of patients have a bone marrow (BM) blast percentage of less than 20% ...
Bhat Ramesh Y RY Department of Paediatrics, Kasturba Medical College, Manipal University, Manipal, Karnataka, - - 2014
Hypomelanosis of Ito (HI) is a neurocutaneous syndrome characterized by hypopigmented cutaneous lesions and extracutaneous manifestations frequently affecting the nervous system and the musculoskeletal system. Dysmorphic features, dental, ophthalmic, gastrointestinal, cardiac, and renal abnormalities are described in a minority of patients. The authors describe a 4-month-old infant having HI with ...
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